Structure information

M3 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

4U14

SPECIES

Rattus norvegicus

RESOLUTION

3.570

PREFERRED CHAIN

A

PUBLICATION DATE

Nov. 26, 2014

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Tiotropium Y148 3.33x33 TM3 hydrophobic
Tiotropium W199 4.57x57 TM4 hydrophobic
Tiotropium W503 6.48x48 TM6 hydrophobic
Tiotropium Y506 6.51x51 TM6 aromatic (edge-to-face)
Tiotropium N507 6.52x52 TM6 polar (hydrogen bond)
Tiotropium N507 6.52x52 TM6 polar (hydrogen bond)
Tiotropium N507 6.52x52 TM6 polar (hydrogen bond)
Tiotropium Y529 7.39x38 TM7 hydrophobic
Tiotropium C532 7.42x41 TM7 hydrophobic

Ligands

Tiotropium

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.

2D interaction plot

PoseView coming soon.

Residue Diagrams

I N G I I T V L A L F G T L F A I F V V 1 L S L A C A D L I I G I V S M N L F T T Y 2 V L L N M V S A N S A V Y D I S L W L D 3 A G V M I G L A W V I S F V L W A P A I 4 Y L I T M I T V P M Y F A A I A T G F T I 5 S A I L L A F I I T W T P Y N I M V L V 6 V P N V T S N I Y C L W Y G L N W Y T 7
Download: PNG | SVG
K Q L K ICL1ECL1 N R W A L ECL1 P L T Y R A K R ICL2ECL2 K R T V P P G E C F I Q F L S ECL2ICL3 Q A S G T E A E A E N F V H P T G S S R S C S S Y E L Q Q Q G V K R S S R R K Y G R C H F W F T T K S W K P S A E Q M D Q D H S S S D S W N N N D A A A S L E N S A S S D E E D I G S E T R A I Y S I V L K L P G H S S I L N S T K L P S S D N L Q V S N E D L G T V D V E R N A H K L Q A Q K S M G D G D N C Q K D F T K L P I Q L E S A V D T G K T S D T N S S A D K T T A T L P L S F K E A T L A K R F A L K T R S Q I T K R K ICL3ECL3 D S C I ECL3N-term M T L H S N S T T S P L F P N I S S S W V H S P S E A G L P L G T V T Q L G S Y N I S Q E T G N F S S N D T S S D P L G G H T N-termC-term L C Q C D K R K R R K Q Q Y Q Q R Q S V I F H K R V P E Q A L C-term I W Q V V F I A F L T G F L A L V T I I G N I L V I V A F K V N T V N N Y F L L S L A C A D L I I G V I S M N L F T T Y I I M G N L A C D L W L S I D Y V A S N A S V M N L L V I S F D R Y F S I T R T T K R A G V M I G L A W V I S F V L W A P A I L F W Q Y F V G E P T I T F G T A I A A F Y M P V T I M T I L Y W R I Y K E T E K R T K E L A G L R M S L I K E K K A A Q T L S A I L L A F I I T W T P Y N I M V L V N T F C P K T Y W N L G Y W L C Y I N S T V N P V C Y A L C N K T F K T F R T T L L
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
M3 receptor
TM3
3x33 3.33x33 Y148
TM4
4x57 4.57x57 W199
TM6
6x48 6.48x48 W503
6x51 6.51x51 Y506
6x52 6.52x52 N507
TM7
7x38 7.39x38 Y529
7x41 7.42x41 C532