Variation Browser

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Receptor Position GPCRdb Segment Variant Mutation type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
Receptor Position GPCRdb Segment Variant Mutation Type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
drd5_human 2 N-term L => P missense 0.0001198 1 8348 0 nan 0.998
drd5_human 4 N-term P => R missense 9.737e-05 1 10270 0 nan 0.041
drd5_human 11 N-term Y => H missense 5.399e-05 1 18522 0 nan 0.0
drd5_human 15 N-term F => L missense 4.137e-05 1 24172 0 nan 0.001
drd5_human 16 N-term A => P missense 7.649e-05 2 26148 0 nan 0.001
drd5_human 16 N-term A => T missense 3.824e-05 1 26148 0 nan 0.011
drd5_human 17 N-term L => V missense 3.59e-05 1 27854 0 nan 0.0
drd5_human 18 N-term Y => D missense 6.893e-05 2 29014 0 nan 0.002
drd5_human 21 N-term L => Q missense 6.005e-05 2 33306 0 nan 0.154
drd5_human 23 N-term Q => H missense 5.442e-05 2 36752 0 nan 0.188
drd5_human 24 N-term G => R missense 2.685e-05 1 37240 0 nan 0.0
drd5_human 25 N-term N => S missense 2.581e-05 1 38750 0 nan 0.004
drd5_human 27 N-term V => L missense 9.833e-05 4 40678 0 1.0 0.001
drd5_human 28 N-term G => E missense 9.717e-05 4 41166 0 nan 0.028
drd5_human 32 N-term G => E missense 2.299e-05 1 43506 0 0.53 0.028
drd5_human 33 1.25x25 TM1 A => T missense 2.283e-05 1 43808 0 0.55 0.003
drd5_human 33 1.25x25 TM1 A => E missense 2.375e-05 1 42100 0 1.0 0.003
drd5_human 34 1.26x26 TM1 P => Q missense 2.193e-05 1 45600 0 0.08 0.001
drd5_human 34 1.26x26 TM1 P => R missense 2.193e-05 1 45600 0 0.05 0.028
drd5_human 37 1.29x29 TM1 G => R missense 1.985e-05 1 50366 0 0.13 0.999
drd5_human 41 1.33x33 TM1 V => A missense 0.0001727 10 57914 0 0.31 0.015
drd5_human 46 1.38x38 TM1 L => P missense 1.26e-05 1 79334 0 0.0 0.962
drd5_human 47 1.39x39 TM1 L => V missense 0.00011 9 81834 0 0.02 0.997
drd5_human 52 1.44x44 TM1 I => T missense 1.031e-05 1 96982 0 0.0 0.034
drd5_human 53 1.45x45 TM1 W => R missense 1.021e-05 1 97956 0 0.22 0.668
drd5_human 54 1.46x46 TM1 T => N missense 9.955e-06 1 100456 0 0.0 0.999
drd5_human 57 1.49x49 TM1 G => D missense 2.815e-05 3 106570 0 0.0 1.0
drd5_human 58 1.50x50 TM1 N => K missense 9.234e-06 1 108292 0 0.0 0.985
drd5_human 61 1.53x53 TM1 V => M missense 0.0001178 13 110388 0 0.0 0.99
drd5_human 62 1.54x54 TM1 C => S missense 0.0001169 13 111192 0 0.0 0.812
drd5_human 63 1.55x55 TM1 A => V missense 1.765e-05 2 113310 0 0.43 0.03
drd5_human 68 1.60x60 TM1 S => R missense 1.712e-05 2 116806 0 0.02 0.864
drd5_human 69 12.48x48 ICL1 R => G missense 8.548e-06 1 116984 0 0.01 0.964
drd5_human 72 12.51x51 ICL1 R => C missense 8.456e-06 1 118258 0 0.0 0.998
drd5_human 75 2.38x38 TM2 M => V missense 1.671e-05 2 119678 0 1.0 0.016
drd5_human 75 2.38x38 TM2 M => T missense 0.00111 133 119798 1 0.07 0.02
drd5_human 76 2.39x39 TM2 T => I missense 8.33e-06 1 120044 0 0.0 0.998
drd5_human 78 2.41x41 TM2 V => I missense 1.662e-05 2 120326 0 0.63 0.021
drd5_human 78 2.41x41 TM2 V => G missense 9.968e-05 12 120386 0 0.04 0.493
drd5_human 83 2.46x46 TM2 L => P missense 3.311e-05 4 120818 0 0.0 1.0
drd5_human 85 2.48x48 TM2 V => A missense 1.651e-05 2 121158 0 0.0 0.863
drd5_human 88 2.51x51 TM2 L => F missense 0.004521 548 121200 1 0.0 1.0
drd5_human 89 2.52x52 TM2 F => S missense 1.65e-05 2 121214 0 0.05 0.857
drd5_human 91 2.54x54 TM2 A => P missense 3.3e-05 4 121214 0 0.0 1.0
drd5_human 91 2.54x54 TM2 A => E missense 8.25e-06 1 121218 0 0.0 1.0
drd5_human 101 2.64x63 TM2 A => T missense 1.649e-05 2 121254 0 0.67 0.08
drd5_human 103 2.66x65 TM2 V => M missense 8.246e-06 1 121266 0 0.0 0.997
drd5_human 106 23.49x49 ECL1 Y => H missense 0.0001731 21 121284 0 0.16 0.071
drd5_human 108 23.51x51 ECL1 P => T missense 3.299e-05 4 121260 0 0.05 0.904
drd5_human 108 23.51x51 ECL1 P => L missense 7.421e-05 9 121272 0 0.42 0.107
drd5_human 110 3.22x22 TM3 G => E missense 7.431e-05 9 121118 0 0.01 0.873
drd5_human 111 3.23x23 TM3 A => V missense 4.124e-05 5 121254 0 0.03 0.223
drd5_human 111 3.23x23 TM3 A => E missense 8.247e-06 1 121254 0 0.13 0.564
drd5_human 113 3.25x25 TM3 C => S missense 8.247e-06 1 121258 0 0.0 0.992
drd5_human 114 3.26x26 TM3 D => N missense 8.247e-06 1 121258 0 0.56 0.055
drd5_human 115 3.27x27 TM3 V => I missense 8.247e-06 1 121254 0 0.64 0.05
drd5_human 115 3.27x27 TM3 V => F missense 2.474e-05 3 121254 0 0.0 0.915
drd5_human 123 3.35x35 TM3 C => Y missense 3.3e-05 4 121230 0 0.0 1.0
drd5_human 125 3.37x37 TM3 T => A missense 8.249e-06 1 121224 0 0.0 1.0
drd5_human 126 3.38x38 TM3 A => V missense 8.25e-06 1 121214 0 0.0 1.0
drd5_human 127 3.39x39 TM3 S => F missense 4.125e-05 5 121200 0 0.0 1.0
drd5_human 131 3.43x43 TM3 L => P missense 8.252e-06 1 121190 0 0.0 1.0
drd5_human 133 3.45x45 TM3 V => I missense 8.259e-06 1 121082 0 0.83 0.037
drd5_human 135 3.47x47 TM3 S => T missense 8.255e-06 1 121146 0 0.0 1.0
drd5_human 138 3.50x50 TM3 R => C missense 2.477e-05 3 121104 0 0.01 1.0 SodiumPocket MicroSwitch GP (contact)
drd5_human 138 3.50x50 TM3 R => L missense 2.477e-05 3 121108 0 0.0 0.999 SodiumPocket MicroSwitch GP (contact)
drd5_human 141 3.53x53 TM3 A => S missense 8.26e-06 1 121072 0 0.0 0.999 GP (contact)
drd5_human 149 34.54x54 ICL2 K => E missense 4.961e-05 6 120952 0 1.0 0.001 GP (contact)
drd5_human 150 34.55x55 ICL2 R => C missense 8.266e-06 1 120972 0 0.01 0.262 GP (contact)
drd5_human 152 34.57x57 ICL2 M => I missense 8.268e-06 1 120942 0 0.0 0.999 GP (contact)
drd5_human 155 4.40x40 TM4 R => H missense 8.275e-06 1 120840 0 0.06 0.126
drd5_human 157 4.42x42 TM4 A => D missense 8.274e-06 1 120858 0 0.0 0.997
drd5_human 158 4.43x43 TM4 L => F missense 1.655e-05 2 120822 0 1.0 0.03
drd5_human 162 4.47x47 TM4 G => R missense 8.282e-06 1 120746 0 0.0 0.762
drd5_human 170 4.55x55 TM4 L => P missense 8.305e-06 1 120406 0 0.0 0.995
drd5_human 171 4.56x56 TM4 I => V missense 8.304e-06 1 120418 0 0.06 0.341
drd5_human 173 4.58x58 TM4 F => L missense 1.665e-05 2 120136 0 0.04 0.914
drd5_human 175 4.60x60 TM4 P => L missense 2.5e-05 3 119978 0 0.0 1.0
drd5_human 176 4.61x61 TM4 V => A missense 7.501e-05 9 119992 0 0.0 0.999
drd5_human 177 4.62x62 TM4 Q => H missense 8.339e-06 1 119920 0 0.08 0.33
drd5_human 179 4.64x64 TM4 N => S missense 1.669e-05 2 119840 0 0.17 0.057
drd5_human 179 4.64x64 TM4 N => T missense 8.344e-06 1 119840 0 0.01 0.392
drd5_human 183 ECL2 D => H missense 8.358e-06 1 119640 0 0.12 0.806
drd5_human 184 ECL2 Q => E missense 8.365e-06 1 119546 0 0.87 0.002
drd5_human 184 ECL2 Q => P missense 8.362e-06 1 119584 0 0.23 0.18
drd5_human 185 ECL2 A => V missense 8.364e-06 1 119558 0 0.31 0.014
drd5_human 188 ECL2 W => L missense 1.672e-05 2 119598 0 0.65 0.003
drd5_human 190 ECL2 G => W missense 1.671e-05 2 119678 0 0.0 0.917
drd5_human 190 ECL2 G => V missense 8.355e-06 1 119694 0 0.03 0.243
drd5_human 191 ECL2 L => P missense 8.353e-06 1 119724 0 0.25 0.0
drd5_human 192 ECL2 D => Y missense 8.35e-06 1 119754 0 0.02 0.328
drd5_human 192 ECL2 D => G missense 1.67e-05 2 119758 0 0.3 0.003
drd5_human 195 ECL2 N => K missense 8.342e-06 1 119872 0 0.39 0.05
drd5_human 196 ECL2 N => H missense 8.34e-06 1 119904 0 0.14 0.004
drd5_human 197 ECL2 L => V missense 1.668e-05 2 119904 0 0.49 0.257
drd5_human 198 ECL2 A => D missense 0.0002084 25 119942 0 0.14 0.016
drd5_human 198 ECL2 A => V missense 1.667e-05 2 119942 0 0.14 0.016
drd5_human 200 ECL2 W => R missense 8.336e-06 1 119966 0 0.35 0.0
drd5_human 201 ECL2 T => A missense 8.331e-06 1 120038 0 0.1 0.869
drd5_human 205 ECL2 E => D missense 8.313e-06 1 120300 0 0.13 0.006
drd5_human 211 ECL2 D => N missense 0.0005554 67 120628 0 0.26 0.005
drd5_human 215 ECL2 E => G missense 8.271e-06 1 120902 0 0.35 0.03
drd5_human 219 45.52x52 ECL2 S => F missense 4.959e-05 6 120996 0 0.1 0.997
drd5_human 226 5.39x40 TM5 A => S missense 8.255e-06 1 121140 0 0.01 1.0
drd5_human 228 5.41x42 TM5 S => P missense 8.252e-06 1 121178 0 0.0 0.984
drd5_human 233 5.46x461 TM5 S => T missense 8.248e-06 1 121238 0 0.0 1.0
drd5_human 234 5.47x47 TM5 F => Y missense 1.65e-05 2 121234 0 0.0 1.0 SodiumPocket MicroSwitch
drd5_human 236 5.49x49 TM5 I => F missense 1.65e-05 2 121228 0 0.0 0.973
drd5_human 238 5.51x51 TM5 V => G missense 4.126e-05 5 121192 0 0.0 0.993
drd5_human 239 5.52x52 TM5 A => V missense 8.253e-06 1 121174 0 0.15 0.042
drd5_human 241 5.54x54 TM5 M => I missense 4.954e-05 6 121122 0 0.06 0.999
drd5_human 241 5.54x54 TM5 M => I missense 6.605e-05 8 121122 0 0.06 0.999
drd5_human 242 5.55x55 TM5 I => V missense 0.0001239 15 121104 0 0.19 0.075
drd5_human 247 5.60x60 TM5 R => C missense 8.295e-06 1 120558 0 0.08 0.908
drd5_human 247 5.60x60 TM5 R => G missense 8.295e-06 1 120558 0 0.0 0.999
drd5_human 247 5.60x60 TM5 R => L missense 2.489e-05 3 120538 0 0.01 0.998
drd5_human 250 5.63x63 TM5 R => C missense 8.305e-06 1 120406 0 0.04 0.998
drd5_human 252 5.65x65 TM5 A => S missense 8.325e-06 1 120116 0 0.0 0.998 GP (contact)
drd5_human 257 5.70x70 TM5 R => H missense 1.674e-05 2 119494 0 0.01 0.351
drd5_human 258 5.71x71 TM5 R => K missense 1.675e-05 2 119438 0 0.04 0.999 GP (contact)
drd5_human 258 5.71x71 TM5 R => S missense 8.376e-06 1 119392 0 0.03 1.0 GP (contact)
drd5_human 259 5.72x72 TM5 I => V missense 0.0001927 23 119342 0 0.01 0.889 GP (contact)
drd5_human 263 5.76x76 TM5 E => G missense 1.689e-05 2 118448 0 0.04 1.0
drd5_human 266 ICL3 A => S missense 8.476e-06 1 117978 0 0.02 0.767
drd5_human 267 ICL3 E => Q missense 8.471e-06 1 118044 0 0.16 0.159
drd5_human 268 ICL3 H => Q missense 0.0003736 44 117760 0 0.13 0.303
drd5_human 268 ICL3 H => Q missense 2.548e-05 3 117760 0 0.13 0.303
drd5_human 269 ICL3 A => T missense 1.702e-05 2 117528 0 0.04 0.532
drd5_human 269 ICL3 A => V missense 0.000179 21 117314 0 0.05 0.127
drd5_human 273 ICL3 R => G missense 8.575e-06 1 116624 0 0.07 0.089
drd5_human 273 ICL3 R => W missense 6.002e-05 7 116624 0 0.02 0.954
drd5_human 273 ICL3 R => Q missense 2.571e-05 3 116682 0 0.4 0.055
drd5_human 275 ICL3 S => T missense 1.741e-05 2 114892 0 0.47 0.139
drd5_human 275 ICL3 S => R missense 8.824e-05 10 113326 0 0.6 0.004
drd5_human 279 ICL3 A => V missense 8.711e-06 1 114796 0 0.23 0.024
drd5_human 285 6.24x24 TM6 R => C missense 8.564e-06 1 116774 0 0.0 0.954
drd5_human 285 6.24x24 TM6 R => S missense 8.564e-06 1 116774 0 0.0 0.664
drd5_human 286 6.25x25 TM6 A => T missense 4.278e-05 5 116866 0 0.78 0.004 GP (contact)
drd5_human 289 6.28x28 TM6 K => R missense 2.56e-05 3 117196 0 0.67 0.052 GP (contact)
drd5_human 290 6.29x29 TM6 K => T missense 8.528e-06 1 117258 0 0.0 0.991 GP (contact)
drd5_human 292 6.31x31 TM6 T => S missense 6.813e-05 8 117414 0 0.01 0.936
drd5_human 293 6.32x32 TM6 K => E missense 1.703e-05 2 117440 0 0.03 0.558 GP (contact)
drd5_human 294 6.33x33 TM6 V => I missense 8.507e-06 1 117546 0 0.03 0.999 GP (contact)
drd5_human 297 6.36x36 TM6 T => S missense 8.429e-06 1 118640 0 0.0 1.0 GP (contact)
drd5_human 299 6.38x38 TM6 S => P missense 8.431e-06 1 118612 0 0.0 0.99
drd5_human 302 6.41x41 TM6 M => T missense 8.423e-05 10 118728 0 0.0 0.904
drd5_human 304 6.43x43 TM6 V => F missense 8.422e-06 1 118734 0 0.0 0.988
drd5_human 306 6.45x45 TM6 V => L missense 8.418e-06 1 118800 0 0.04 1.0
drd5_human 312 6.51x51 TM6 F => L missense 1.679e-05 2 119124 0 0.01 1.0
drd5_human 314 6.53x53 TM6 I => N missense 8.387e-06 1 119234 0 0.0 0.88
drd5_human 314 6.53x53 TM6 I => T missense 1.677e-05 2 119234 0 0.0 0.426
drd5_human 315 6.54x54 TM6 L => P missense 5.867e-05 7 119304 0 0.0 0.999
drd5_human 319 6.58x58 TM6 V => I missense 8.349e-06 1 119770 0 0.07 0.856
drd5_human 320 6.59x59 TM6 P => R missense 8.341e-06 1 119896 0 0.0 1.0
drd5_human 322 6.61x61 TM6 C => F missense 1.665e-05 2 120128 0 0.01 1.0
drd5_human 323 6.62x62 TM6 S => N missense 4.159e-05 5 120214 0 0.36 0.008
drd5_human 325 6.64x64 TM6 H => Y missense 1.662e-05 2 120338 0 0.04 0.063
drd5_human 328 ECL3 G => D missense 8.248e-06 1 121240 0 0.61 0.006
drd5_human 330 7.24x23 TM7 P => Q missense 0.01211 1468 121242 33 0.64 0.016
drd5_human 330 7.24x23 TM7 P => L missense 4.949e-05 6 121242 0 0.3 0.002
drd5_human 331 7.25x24 TM7 A => T missense 8.246e-06 1 121272 0 0.15 0.033
drd5_human 336 7.30x29 TM7 V => I missense 1.649e-05 2 121314 0 0.25 0.981
drd5_human 337 7.31x30 TM7 S => C missense 1.648e-05 2 121332 0 0.0 0.988
drd5_human 337 7.31x30 TM7 S => G missense 8.242e-06 1 121332 0 0.14 0.248
drd5_human 337 7.31x30 TM7 S => T missense 8.242e-06 1 121332 0 0.01 0.633
drd5_human 338 7.32x31 TM7 E => D missense 8.241e-06 1 121340 0 0.41 0.042
drd5_human 339 7.33x32 TM7 T => N missense 8.241e-06 1 121346 0 0.01 0.987
drd5_human 345 7.39x38 TM7 V => I missense 5.767e-05 7 121374 0 0.03 0.573
drd5_human 346 7.40x39 TM7 W => C missense 8.239e-06 1 121374 0 0.0 0.942
drd5_human 347 7.41x40 TM7 F => I missense 8.239e-06 1 121376 0 0.07 0.603
drd5_human 347 7.41x40 TM7 F => L missense 8.238e-06 1 121382 0 0.3 0.052
drd5_human 348 7.42x41 TM7 G => S missense 1.648e-05 2 121382 0 0.0 0.996
drd5_human 348 7.42x41 TM7 G => R missense 8.238e-06 1 121382 0 0.01 0.999
drd5_human 350 7.44x43 TM7 A => P missense 8.238e-06 1 121384 0 0.0 0.983 SodiumPocket MicroSwitch
drd5_human 352 7.46x46 TM7 S => P missense 6.59e-05 8 121390 0 0.0 1.0
drd5_human 352 7.46x46 TM7 S => F missense 8.238e-06 1 121392 0 0.0 1.0
drd5_human 354 7.48x48 TM7 L => V missense 8.238e-06 1 121392 0 0.1 1.0
drd5_human 357 7.51x51 TM7 V => L missense 2.471e-05 3 121392 0 0.05 0.281
drd5_human 357 7.51x51 TM7 V => F missense 8.238e-06 1 121392 0 0.05 0.866
drd5_human 358 7.52x52 TM7 I => T missense 8.238e-06 1 121388 0 0.0 0.978
drd5_human 359 7.53x53 TM7 Y => S missense 1.648e-05 2 121394 0 0.0 1.0 SodiumPocket MicroSwitch
drd5_human 360 7.54x54 TM7 A => T missense 8.238e-06 1 121392 0 0.01 1.0
drd5_human 361 7.55x55 TM7 F => V missense 4.943e-05 6 121394 0 0.0 0.839 GP (contact)
drd5_human 362 7.56x56 TM7 N => K missense 1.648e-05 2 121396 0 0.0 0.973 GP (contact)
drd5_human 364 8.48x48 H8 D => G missense 6.59e-05 8 121398 0 0.0 0.977 GP (contact)
drd5_human 365 8.49x49 H8 F => C missense 8.238e-06 1 121392 0 0.0 1.0 GP (contact)
drd5_human 366 8.50x50 H8 Q => R missense 0.0001565 19 121390 0 1.0 0.0
drd5_human 374 8.58x58 H8 G => R missense 3.295e-05 4 121382 0 0.04 0.555
drd5_human 374 8.58x58 H8 G => R missense 8.238e-06 1 121382 0 0.04 0.555
drd5_human 375 8.59x59 H8 C => Y missense 8.255e-06 1 121146 0 0.0 0.885
drd5_human 381 C-term R => C missense 8.24e-06 1 121366 0 0.03 0.772
drd5_human 382 C-term T => M missense 8.239e-06 1 121378 0 0.0 0.886
drd5_human 387 C-term V => E missense 8.239e-06 1 121378 0 0.0 0.846
drd5_human 388 C-term N => Y missense 8.239e-06 1 121380 0 0.0 0.903
drd5_human 394 C-term I => F missense 1.648e-05 2 121386 0 0.04 0.128
drd5_human 394 C-term I => T missense 1.648e-05 2 121386 0 0.05 0.06
drd5_human 395 C-term S => F missense 0.0002389 29 121382 0 0.01 0.999
drd5_human 397 C-term N => H missense 8.238e-06 1 121384 0 1.0 0.005
drd5_human 399 C-term D => Y missense 8.238e-06 1 121386 0 0.0 0.949
drd5_human 401 C-term V => I missense 8.239e-06 1 121380 0 0.19 0.002
drd5_human 407 C-term A => T missense 8.238e-06 1 121394 0 0.21 0.003
drd5_human 407 C-term A => V missense 8.238e-06 1 121396 0 0.66 0.002
drd5_human 413 C-term M => V missense 1.648e-05 2 121392 0 0.63 0.001
drd5_human 413 C-term M => L missense 8.238e-06 1 121392 0 1.0 0.011
drd5_human 413 C-term M => R missense 8.238e-06 1 121394 0 0.21 0.004
drd5_human 418 C-term V => I missense 0.0001318 16 121396 1 0.3 0.06
drd5_human 418 C-term V => F missense 8.238e-06 1 121396 0 0.01 0.897
drd5_human 423 C-term R => Q missense 2.471e-05 3 121386 0 0.57 0.053
drd5_human 427 C-term N => K missense 8.238e-06 1 121388 0 1.0 0.0
drd5_human 428 C-term D => N missense 8.238e-06 1 121388 0 0.38 0.004
drd5_human 433 C-term P => R missense 8.239e-06 1 121378 0 0.12 0.005
drd5_human 438 C-term F => S missense 6.592e-05 8 121356 0 1.0 0.0
drd5_human 438 C-term F => L missense 8.24e-06 1 121354 0 0.17 0.0
drd5_human 446 C-term D => G missense 5.773e-05 7 121258 0 0.4 0.002
drd5_human 447 C-term G => S missense 4.124e-05 5 121250 0 0.85 0.101
drd5_human 453 C-term S => T missense 8.255e-06 1 121132 0 0.04 0.254
drd5_human 453 C-term S => C missense 0.0001321 16 121126 1 0.01 0.765
drd5_human 460 C-term E => D missense 8.304e-06 1 120424 0 0.3 0.032
drd5_human 461 C-term G => R missense 3.323e-05 4 120362 0 0.08 0.021
drd5_human 461 C-term G => V missense 8.311e-06 1 120322 0 0.14 0.015
drd5_human 462 C-term E => D missense 8.344e-06 1 119848 0 0.42 0.011
drd5_human 465 C-term L => S missense 3.354e-05 4 119260 0 0.01 0.191
drd5_human 469 C-term T => A missense 5.958e-05 7 117484 0 0.12 0.005
drd5_human 475 C-term G => V missense 8.8e-06 1 113632 0 0.0 0.796
drd5_human 477 C-term H => R missense 2.703e-05 3 111002 0 0.07 0.448
drd5_human 23 N-term Q => Ter stop gained 2.802e-05 1 35686 0 None None
drd5_human 62 1.54x54 TM1 C => Ter stop gained 0.0009874 111 112420 0 None None
drd5_human 113 3.25x25 TM3 C => Ter stop gained 8.247e-06 1 121250 0 None None
drd5_human 116 3.28x28 TM3 W => Ter stop gained 5.773e-05 7 121252 0 None None
drd5_human 165 4.50x50 TM4 W => Ter stop gained 8.288e-06 1 120660 0 None None
drd5_human 197 ECL2 L => TrpfsTer16 frameshift 8.34e-06 1 119910 0 None None
drd5_human 204 ECL2 E => Ter stop gained 4.16e-05 5 120180 0 None None
drd5_human 223 5.36x37 TM5 R => Ter stop gained 1.652e-05 2 121076 0 None None
drd5_human 252 5.65x65 TM5 A => ProfsTer49 frameshift 8.323e-06 1 120152 0 None None GP (contact)
drd5_human 255 5.68x68 TM5 Q => Ter stop gained 8.348e-06 1 119796 0 None None GP (contact)
drd5_human 278 ICL3 C => Ter stop gained 3.496e-05 4 114422 0 None None
drd5_human 291 6.30x30 TM6 E => GlyfsTer26 frameshift 2.558e-05 3 117258 0 None None SodiumPocket MicroSwitch
drd5_human 312 6.51x51 TM6 F => LeufsTer5 frameshift 8.401e-06 1 119036 0 None None
drd5_human 335 7.29x28 TM7 C => Ter stop gained 0.001748 212 121312 1 None None
drd5_human 338 7.32x31 TM7 E => AspfsTer13 frameshift 2.473e-05 3 121334 0 None None
drd5_human 366 8.50x50 H8 Q => ArgfsTer22 frameshift 1.648e-05 2 121394 0 None None
drd5_human 366 8.50x50 H8 Q => Ter stop gained 1.648e-05 2 121392 0 None None
drd5_human 371 8.55x55 H8 Q => Ter stop gained 8.239e-06 1 121380 0 None None
drd5_human 375 8.59x59 H8 C => Ter stop gained 4.943e-05 6 121382 0 None None
drd5_human 396 C-term Y => Ter stop gained 8.238e-06 1 121384 0 None None
drd5_human 413 C-term M => AspfsTer35 frameshift 8.238e-06 1 121394 0 None None
drd5_human 429 C-term E => Ter stop gained 1.648e-05 2 121386 0 None None
drd5_human 441 C-term Y => Ter stop gained 8.243e-06 1 121320 0 None None
drd5_human 455 C-term W => Ter stop gained 8.262e-06 1 121040 0 None None
drd5_human 462 C-term E => GlyfsTer4 frameshift 8.32e-06 1 120196 0 None None
drd5_human 477 C-term H => IlefsTer5 frameshift 1.771e-05 2 112920 0 None None


Residue

Diagrams

R H L R ICL1ECL1 A G Y W P F ECL1 P F R Y K R K M ICL2ECL2 W H R D Q A A S W G G L D L P N N L A N W T P W E E D F W E P D V N A E N C D S S L ECL2ICL3 R A A E H A Q S C R S S A A C A P D T S L ICL3ECL3 P E G P ECL3N-term M L P P G S N G T A Y P G Q F A L Y Q Q L A Q G N A V G G S A G N-termC-term S H F C S R T P V E T V N I S N E L I S Y N Q D I V F H K E I A A A Y I H M M P N A V T P G N R E V D N D E E E G P F D R M F Q I Y Q T S P D G D P V A E S V W E L D C E G E I S L D K I T P F T P N G F H C-term A P P L G P S Q V V T A C L L T L L I I W T L L G N V L V C A A I V R S A N M T N V F I V S L A V S D L F V A L L V M P W K A V A E V G A F C D V W V A F D I M C S T A S I L N L C V I S V D R Y W A I S R T Q R M A L V M V G L A W T L S I L I S F I P V Q L N N R T Y A I S S S L I S F Y I P V A I M I V T Y T R I Y R I A Q V Q I R R I S S L E R A S I K K E T K V L K T L S V I M G V F V C C W L P F F I L N C M V P F C S G H P A G F P C V S E T T F D V F V W F G W A N S S L N P V I Y A F N A D F A Q L Q K V F L G C
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