C5a1 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 7.3 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 46%) PDB: 6DDE

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 74.8 17.6 7.6
Side-chains 21.4 67.9 10.7

Number of backbone templates: 4
Number of rotamer templates: 20

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5O9H
6DDE
4DKL
5UNH
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 29 - - - -
N-term 30 - - - -
N-term 31 - - - -
N-term 32 - - - -
N-term 33 - - - -
TM1 34 1.29x29 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 35 1.30x30 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 36 1.31x31 μ receptor 6DDE C5a1 receptor 5O9H
TM1 37 1.32x32 μ receptor 6DDE C5a1 receptor 5O9H
TM1 38 1.33x33 μ receptor 6DDE C5a1 receptor 5O9H
TM1 39 1.34x34 μ receptor 6DDE NTS1 receptor 4XES
TM1 40 1.35x35 μ receptor 6DDE C5a1 receptor 5O9H
TM1 41 1.36x36 μ receptor 6DDE C5a1 receptor 5O9H
TM1 42 1.37x37 μ receptor 6DDE C5a1 receptor 5O9H
TM1 43 1.38x38 μ receptor 6DDE NTS1 receptor 4XES
TM1 44 1.39x39 μ receptor 6DDE C5a1 receptor 5O9H
TM1 45 1.40x40 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 46 1.41x41 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 47 1.42x42 μ receptor 6DDE μ receptor 6DDE
TM1 48 1.43x43 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 49 1.44x44 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 50 1.45x45 μ receptor 6DDE μ receptor 6DDE
TM1 51 1.46x46 μ receptor 6DDE μ receptor 6DDE
TM1 52 1.47x47 μ receptor 6DDE PAF receptor 5ZKQ
TM1 53 1.48x48 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 54 1.49x49 μ receptor 6DDE μ receptor 6DDE
TM1 55 1.50x50 μ receptor 6DDE μ receptor 6DDE
TM1 56 1.51x51 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 57 1.52x52 μ receptor 6DDE μ receptor 6DDE
TM1 58 1.53x53 μ receptor 6DDE μ receptor 6DDE
TM1 59 1.54x54 μ receptor 6DDE C5a1 receptor 5O9H
TM1 60 1.55x55 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 61 1.56x56 μ receptor 6DDE μ receptor 6DDE
TM1 62 1.57x57 μ receptor 6DDE C5a1 receptor 5O9H
TM1 63 1.58x58 μ receptor 6DDE NTS1 receptor 4XES
TM1 64 1.59x59 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 65 1.60x60 μ receptor 6DDE C5a1 receptor 5O9H
ICL1 66 - - - -
ICL1 67 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL1 68 - - - -
TM2 69 2.37x37 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 70 2.38x38 μ receptor 6DDE C5a1 receptor 5O9H
TM2 71 2.39x39 μ receptor 6DDE C5a1 receptor 5O9H
TM2 72 2.40x40 μ receptor 6DDE FFA1 receptor 5TZY
TM2 73 2.41x41 μ receptor 6DDE μ receptor 6DDE
TM2 74 2.42x42 μ receptor 6DDE C5a1 receptor 5O9H
TM2 75 2.43x43 μ receptor 6DDE C5a1 receptor 5O9H
TM2 76 2.44x44 μ receptor 6DDE PAR1 3VW7
TM2 77 2.45x45 μ receptor 6DDE μ receptor 6DDE
TM2 78 2.46x46 μ receptor 6DDE μ receptor 6DDE
TM2 79 2.47x47 μ receptor 6DDE μ receptor 6DDE
TM2 80 2.48x48 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 81 2.49x49 μ receptor 6DDE μ receptor 6DDE
TM2 82 2.50x50 μ receptor 6DDE μ receptor 6DDE
TM2 83 2.51x51 μ receptor 6DDE P2Y1 receptor 4XNW
TM2 84 2.52x52 μ receptor 6DDE μ receptor 6DDE
TM2 85 2.53x53 μ receptor 6DDE PAR2 5NDD
TM2 86 2.54x54 μ receptor 6DDE C5a1 receptor 5O9H
TM2 87 2.55x55 μ receptor 6DDE P2Y1 receptor 4XNW
TM2 88 2.56x56 μ receptor 6DDE NTS1 receptor 4XES
TM2 89 2.57x57 μ receptor 6DDE μ receptor 6DDE
TM2 90 2.58x58 μ receptor 6DDE μ receptor 6DDE
TM2 91 2.59x59 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 92 2.60x60 μ receptor 6DDE P2Y1 receptor 4XNW
TM2 93 2.61x61 μ receptor 6DDE C5a1 receptor 5O9H
TM2 94 2.62x62 μ receptor 6DDE A2A receptor 3QAK
TM2 95 2.63x63 μ receptor 6DDE P2Y12 receptor 4NTJ
TM2 96 2.64x64 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 97 2.65x65 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM2 98 2.66x66 μ receptor 6DDE C5a1 receptor 5O9H
TM2 99 2.67x67 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 100 - - - -
ECL1 101 23.49x49 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 102 23.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 103 23.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 104 23.52x52 - - - -
TM3 105 3.21x21 μ receptor 6DDE μ receptor 6DDE
TM3 106 3.22x22 μ receptor 6DDE C5a1 receptor 5O9H
TM3 107 3.23x23 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 108 3.24x24 μ receptor 6DDE C5a1 receptor 5O9H
TM3 109 3.25x25 μ receptor 6DDE μ receptor 6DDE
TM3 110 3.26x26 μ receptor 6DDE C5a1 receptor 5O9H
TM3 111 3.27x27 μ receptor 6DDE μ receptor 6DDE
TM3 112 3.28x28 μ receptor 6DDE PAR2 5NDD
TM3 113 3.29x29 μ receptor 6DDE C5a1 receptor 5O9H
TM3 114 3.30x30 μ receptor 6DDE μ receptor 6DDE
TM3 115 3.31x31 μ receptor 6DDE NTS1 receptor 4XES
TM3 116 3.32x32 μ receptor 6DDE C5a1 receptor 5O9H
TM3 117 3.33x33 μ receptor 6DDE A2A receptor 4UHR
TM3 118 3.34x34 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 119 3.35x35 μ receptor 6DDE μ receptor 6DDE
TM3 120 3.36x36 μ receptor 6DDE μ receptor 6DDE
TM3 121 3.37x37 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 122 3.38x38 μ receptor 6DDE NTS1 receptor 4XES
TM3 123 3.39x39 μ receptor 6DDE μ receptor 6DDE
TM3 124 3.40x40 μ receptor 6DDE μ receptor 6DDE
TM3 125 3.41x41 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 126 3.42x42 μ receptor 6DDE PAR1 3VW7
TM3 127 3.43x43 μ receptor 6DDE μ receptor 6DDE
TM3 128 3.44x44 μ receptor 6DDE NTS1 receptor 4XES
TM3 129 3.45x45 μ receptor 6DDE μ receptor 6DDE
TM3 130 3.46x46 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 131 3.47x47 μ receptor 6DDE μ receptor 6DDE
TM3 132 3.48x48 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 133 3.49x49 μ receptor 6DDE μ receptor 6DDE
TM3 134 3.50x50 μ receptor 6DDE μ receptor 6DDE
TM3 135 3.51x51 μ receptor 6DDE PAR1 3VW7
TM3 136 3.52x52 μ receptor 6DDE NTS1 receptor 4XES
TM3 137 3.53x53 μ receptor 6DDE C5a1 receptor 5O9H
TM3 138 3.54x54 μ receptor 6DDE μ receptor 6DDE
TM3 139 3.55x55 μ receptor 6DDE C5a1 receptor 5O9H
TM3 140 3.56x56 μ receptor 6DDE 5-HT2B receptor 4IB4
ICL2 141 34.50x50 - - - -
ICL2 142 34.51x51 C5a1 receptor 5O9H C5a1 receptor 6C1R
ICL2 143 34.52x52 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 144 34.53x53 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 145 34.54x54 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 146 34.55x55 C5a1 receptor 5O9H C5a1 receptor 6C1R
ICL2 147 34.56x56 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 148 34.57x57 - - - -
TM4 149 4.38x38 μ receptor 6DDE C5a1 receptor 5O9H
TM4 150 4.39x39 μ receptor 6DDE PAR2 5NDD
TM4 151 4.40x40 μ receptor 6DDE PAR1 3VW7
TM4 152 4.41x41 μ receptor 6DDE C5a1 receptor 5O9H
TM4 153 4.42x42 μ receptor 6DDE μ receptor 6DDE
TM4 154 4.43x43 μ receptor 6DDE FFA1 receptor 5TZY
TM4 155 4.44x44 μ receptor 6DDE μ receptor 6DDE
TM4 156 4.45x45 μ receptor 6DDE C5a1 receptor 6C1R
TM4 157 4.46x46 μ receptor 6DDE PAR1 3VW7
TM4 158 4.47x47 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM4 159 4.48x48 μ receptor 6DDE 5-HT2B receptor 4IB4
TM4 160 4.49x49 μ receptor 6DDE C5a1 receptor 5O9H
TM4 161 4.50x50 μ receptor 6DDE μ receptor 6DDE
TM4 162 4.51x51 μ receptor 6DDE C5a1 receptor 5O9H
TM4 163 4.52x52 μ receptor 6DDE μ receptor 6DDE
TM4 164 4.53x53 μ receptor 6DDE PAR1 3VW7
TM4 165 4.54x54 μ receptor 6DDE PAR2 5NDD
TM4 166 4.55x55 μ receptor 6DDE PAR2 5NDD
TM4 167 4.56x56 μ receptor 6DDE NTS1 receptor 4XES
TM4 168 4.57x57 C5a1 receptor 5O9H PAR2 5NDD
TM4 169 4.58x59 C5a1 receptor 5O9H PAR2 5NDD
TM4 170 4.59x60 μ receptor 6DDE PAR2 5NDD
TM4 171 4.60x61 μ receptor 6DDE C5a1 receptor 5O9H
TM4 172 4.61x62 μ receptor 6DDE μ receptor 6DDE
TM4 173 4.62x63 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 174 4.63x64 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 175 4.64x65 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 176 - - - -
ECL2 177 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 178 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 179 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 180 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 181 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 182 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 183 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 184 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 185 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 186 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 187 - - - -
ECL2 188 45.50x50 μ receptor 6DDE μ receptor 6DDE
ECL2 189 45.51x51 μ receptor 6DDE C5a1 receptor 5O9H
ECL2 190 45.52x52 μ receptor 6DDE 5-HT1B receptor 4IAQ
ECL2 191 - - - -
ECL2 192 AT2 receptor 5UNH - -
ECL2 193 AT2 receptor 5UNH - -
ECL2 194 - - - -
TM5 195 5.31x32 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM5 196 5.32x33 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM5 197 5.33x34 μ receptor 6DDE P2Y1 receptor 4XNW
TM5 198 5.34x35 μ receptor 6DDE C5a1 receptor 5O9H
TM5 199 5.35x36 μ receptor 6DDE μ receptor 6DDE
TM5 200 5.36x37 μ receptor 6DDE C5a1 receptor 5O9H
TM5 201 5.37x38 μ receptor 6DDE C5a1 receptor 5O9H
TM5 202 5.38x39 μ receptor 6DDE NTS1 receptor 4XES
TM5 203 5.39x40 μ receptor 6DDE C5a1 receptor 5O9H
TM5 204 5.40x41 μ receptor 6DDE μ receptor 6DDE
TM5 205 5.41x42 μ receptor 6DDE NTS1 receptor 4XES
TM5 206 5.42x43 μ receptor 6DDE C5a1 receptor 5O9H
TM5 207 5.43x44 μ receptor 6DDE C5a1 receptor 5O9H
TM5 208 5.44x45 μ receptor 6DDE P2Y1 receptor 4XNW
TM5 209 5.45x46 μ receptor 6DDE FFA1 receptor 5TZY
TM5 210 5.46x461 μ receptor 6DDE C5a1 receptor 5O9H
TM5 211 5.47x47 μ receptor 6DDE μ receptor 6DDE
TM5 212 5.48x48 μ receptor 6DDE PAR2 5NDD
TM5 213 5.49x49 μ receptor 6DDE C5a1 receptor 5O9H
TM5 214 5.50x50 μ receptor 6DDE μ receptor 6DDE
TM5 215 5.51x51 μ receptor 6DDE P2Y1 receptor 4XNW
TM5 216 5.52x52 μ receptor 6DDE NTS1 receptor 4XES
TM5 217 5.53x53 μ receptor 6DDE C5a1 receptor 5O9H
TM5 218 5.54x54 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM5 219 5.55x55 μ receptor 6DDE μ receptor 6DDE
TM5 220 5.56x56 μ receptor 6DDE NTS1 receptor 4XES
TM5 221 5.57x57 μ receptor 6DDE μ receptor 6DDE
TM5 222 5.58x58 μ receptor 6DDE μ receptor 6DDE
TM5 223 5.59x59 μ receptor 6DDE NTS1 receptor 4XES
TM5 224 5.60x60 μ receptor 6DDE C5a1 receptor 5O9H
TM5 225 5.61x61 μ receptor 6DDE P2Y1 receptor 4XNW
TM5 226 5.62x62 μ receptor 6DDE FFA1 receptor 5TZY
TM5 227 5.63x63 μ receptor 6DDE μ receptor 6DDE
TM5 228 5.64x64 μ receptor 6DDE μ receptor 6DDE
TM5 229 5.65x65 μ receptor 6DDE C5a1 receptor 5O9H
TM5 230 5.66x66 μ receptor 6DDE C5a1 receptor 5O9H
TM5 231 5.67x67 μ receptor 6DDE μ receptor 6DDE
TM5 232 5.68x68 μ receptor 6DDE C5a1 receptor 6C1R
ICL3 233 μ receptor 6DDE μ receptor 6DDE
ICL3 234 μ receptor 6DDE - -
ICL3 235 μ receptor 6DDE - -
ICL3 236 μ receptor 6DDE - -
ICL3 237 μ receptor 6DDE - -
TM6 238 6.31x31 μ receptor 6DDE C5a1 receptor 6C1R
TM6 239 6.32x32 μ receptor 6DDE PAR2 5NDD
TM6 240 6.33x33 μ receptor 6DDE C5a1 receptor 5O9H
TM6 241 6.34x34 μ receptor 6DDE C5a1 receptor 5O9H
TM6 242 6.35x35 μ receptor 6DDE 5-HT1B receptor 5V54
TM6 243 6.36x36 μ receptor 6DDE NTS1 receptor 4XES
TM6 244 6.37x37 μ receptor 6DDE μ receptor 6DDE
TM6 245 6.38x38 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 246 6.39x39 μ receptor 6DDE NTS1 receptor 4XES
TM6 247 6.40x40 μ receptor 6DDE μ receptor 6DDE
TM6 248 6.41x41 μ receptor 6DDE μ receptor 6DDE
TM6 249 6.42x42 μ receptor 6DDE μ receptor 6DDE
TM6 250 6.43x43 μ receptor 6DDE C5a1 receptor 5O9H
TM6 251 6.44x44 μ receptor 6DDE μ receptor 6DDE
TM6 252 6.45x45 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 253 6.46x46 μ receptor 6DDE PAR1 3VW7
TM6 254 6.47x47 μ receptor 6DDE C5a1 receptor 5O9H
TM6 255 6.48x48 μ receptor 6DDE μ receptor 6DDE
TM6 256 6.49x49 μ receptor 6DDE NTS1 receptor 4XES
TM6 257 6.50x50 μ receptor 6DDE μ receptor 6DDE
TM6 258 6.51x51 μ receptor 6DDE NTS1 receptor 4XES
TM6 259 6.52x52 μ receptor 6DDE C5a1 receptor 5O9H
TM6 260 6.53x53 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 261 6.54x54 μ receptor 6DDE 5-HT2B receptor 4IB4
TM6 262 6.55x55 μ receptor 6DDE FFA1 receptor 5KW2
TM6 263 6.56x56 μ receptor 6DDE μ receptor 6DDE
TM6 264 6.57x57 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 265 6.58x58 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM6 266 6.59x59 μ receptor 6DDE C5a1 receptor 5O9H
TM6 267 6.60x60 μ receptor 6DDE PAR2 5NDD
TM6 268 6.61x61 μ receptor 6DDE C5a1 receptor 5O9H
ECL3 269 - - - -
ECL3 270 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL3 271 - - - -
TM7 272 7.25x24 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 273 7.26x25 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 274 7.27x26 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 275 7.28x27 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 276 7.29x28 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 277 7.30x29 μ receptor 6DDE C5a1 receptor 5O9H
TM7 278 7.31x30 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 279 7.32x31 μ receptor 6DDE C5a1 receptor 5O9H
TM7 280 7.33x32 μ receptor 6DDE C5a1 receptor 5O9H
TM7 281 7.34x33 μ receptor 6DDE PAR2 5NDD
TM7 282 7.35x34 μ receptor 6DDE C5a1 receptor 5O9H
TM7 283 7.36x35 μ receptor 6DDE C5a1 receptor 5O9H
TM7 284 7.37x36 μ receptor 6DDE NTS1 receptor 4XES
TM7 285 7.38x37 μ receptor 6DDE PAR1 3VW7
TM7 286 7.39x38 μ receptor 6DDE PAR1 3VW7
TM7 287 7.40x39 μ receptor 6DDE C5a1 receptor 5O9H
TM7 288 7.41x40 μ receptor 6DDE C5a1 receptor 5O9H
TM7 289 7.42x41 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 290 7.43x42 μ receptor 6DDE μ receptor 6DDE
TM7 291 7.44x43 μ receptor 6DDE PAR1 3VW7
TM7 292 7.45x45 μ receptor 6DDE μ receptor 6DDE
TM7 293 7.46x46 μ receptor 6DDE PAR1 3VW7
TM7 294 7.47x47 μ receptor 6DDE μ receptor 6DDE
TM7 295 7.48x48 μ receptor 6DDE PAR2 5NDD
TM7 296 7.49x49 μ receptor 6DDE μ receptor 6DDE
TM7 297 7.50x50 μ receptor 6DDE μ receptor 6DDE
TM7 298 7.51x51 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 299 7.52x52 μ receptor 6DDE PAR1 3VW7
TM7 300 7.53x53 μ receptor 6DDE μ receptor 6DDE
TM7 301 7.54x54 μ receptor 6DDE C5a1 receptor 5O9H
TM7 302 7.55x55 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 303 7.56x56 C5a1 receptor 5O9H C5a1 receptor 5O9H
H8 304 8.47x47 μ receptor 4DKL CCR2 5T1A
H8 305 8.48x48 μ receptor 4DKL A1 receptor 5UEN
H8 306 8.49x49 μ receptor 4DKL - -
H8 307 8.50x50 μ receptor 4DKL μ receptor 4DKL
H8 308 8.51x51 μ receptor 4DKL AT2 receptor 5UNF
H8 309 8.52x52 μ receptor 4DKL - -
H8 310 8.53x53 μ receptor 4DKL - -
H8 311 8.54x54 μ receptor 4DKL CCR2 5T1A
H8 312 8.55x55 μ receptor 4DKL A2A receptor 4UHR
H8 313 8.56x56 μ receptor 4DKL 5-HT1B receptor 4IAQ
C-term 314 - - - -
C-term 315 - - - -
C-term 316 - - - -
C-term 317 - - - -
C-term 318 - - - -