C5a2 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 7.1 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 39%) PDB: 6DDE

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 73.5 18.0 8.5
Side-chains 17.3 60.8 21.9

Number of backbone templates: 4
Number of rotamer templates: 36

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5O9H
6DDE
5UNH
5LWE
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 27 - - - -
N-term 28 - - - -
N-term 29 - - - -
N-term 30 - - - -
N-term 31 - - - -
TM1 32 1.29x29 C5a1 receptor 5O9H - -
TM1 33 1.30x30 C5a1 receptor 5O9H 5-HT1B receptor 4IAQ
TM1 34 1.31x31 μ receptor 6DDE PAR1 3VW7
TM1 35 1.32x32 μ receptor 6DDE - -
TM1 36 1.33x33 μ receptor 6DDE PAR2 5NDD
TM1 37 1.34x34 μ receptor 6DDE AT2 receptor 5UNG
TM1 38 1.35x35 μ receptor 6DDE - -
TM1 39 1.36x36 μ receptor 6DDE C5a1 receptor 5O9H
TM1 40 1.37x37 μ receptor 6DDE CCR9 5LWE
TM1 41 1.38x38 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 42 1.39x39 μ receptor 6DDE μ receptor 6DDE
TM1 43 1.40x40 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 44 1.41x41 μ receptor 6DDE NTS1 receptor 4XES
TM1 45 1.42x42 μ receptor 6DDE PAF receptor 5ZKQ
TM1 46 1.43x43 μ receptor 6DDE PAR1 3VW7
TM1 47 1.44x44 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 48 1.45x45 μ receptor 6DDE μ receptor 6DDE
TM1 49 1.46x46 μ receptor 6DDE μ receptor 6DDE
TM1 50 1.47x47 μ receptor 6DDE PAF receptor 5ZKQ
TM1 51 1.48x48 μ receptor 6DDE PAR1 3VW7
TM1 52 1.49x49 μ receptor 6DDE μ receptor 6DDE
TM1 53 1.50x50 μ receptor 6DDE μ receptor 6DDE
TM1 54 1.51x51 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 55 1.52x52 μ receptor 6DDE PAR1 3VW7
TM1 56 1.53x53 μ receptor 6DDE μ receptor 6DDE
TM1 57 1.54x54 μ receptor 6DDE - -
TM1 58 1.55x55 μ receptor 6DDE PAR2 5NDD
TM1 59 1.56x56 μ receptor 6DDE μ receptor 6DDE
TM1 60 1.57x57 μ receptor 6DDE FFA1 receptor 5TZY
TM1 61 1.58x58 μ receptor 6DDE CXCR4 3ODU
TM1 62 1.59x59 μ receptor 6DDE ETB receptor 5X93
TM1 63 1.60x60 μ receptor 6DDE - -
ICL1 64 - - - -
ICL1 65 C5a1 receptor 5O9H - -
ICL1 66 - - - -
TM2 67 2.37x37 C5a1 receptor 5O9H apelin receptor 5VBL
TM2 68 2.38x38 μ receptor 6DDE A2A receptor 4UHR
TM2 69 2.39x39 μ receptor 6DDE US28 4XT1
TM2 70 2.40x40 μ receptor 6DDE FFA1 receptor 5TZY
TM2 71 2.41x41 μ receptor 6DDE LPA6 receptor 5XSZ
TM2 72 2.42x42 μ receptor 6DDE C5a1 receptor 5O9H
TM2 73 2.43x43 μ receptor 6DDE NTS1 receptor 4XES
TM2 74 2.44x44 μ receptor 6DDE PAR1 3VW7
TM2 75 2.45x45 μ receptor 6DDE PAR1 3VW7
TM2 76 2.46x46 μ receptor 6DDE μ receptor 6DDE
TM2 77 2.47x47 μ receptor 6DDE μ receptor 6DDE
TM2 78 2.48x48 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 79 2.49x49 μ receptor 6DDE μ receptor 6DDE
TM2 80 2.50x50 μ receptor 6DDE μ receptor 6DDE
TM2 81 2.51x51 μ receptor 6DDE PAR2 5NDD
TM2 82 2.52x52 μ receptor 6DDE μ receptor 6DDE
TM2 83 2.53x53 μ receptor 6DDE - -
TM2 84 2.54x54 μ receptor 6DDE C5a1 receptor 5O9H
TM2 85 2.55x55 μ receptor 6DDE NTS1 receptor 4XES
TM2 86 2.56x56 μ receptor 6DDE FFA1 receptor 5TZY
TM2 87 2.57x57 μ receptor 6DDE μ receptor 6DDE
TM2 88 2.58x58 μ receptor 6DDE μ receptor 6DDE
TM2 89 2.59x59 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 90 2.60x60 μ receptor 6DDE P2Y1 receptor 4XNW
TM2 91 2.61x61 μ receptor 6DDE FFA1 receptor 5TZY
TM2 92 2.62x62 μ receptor 6DDE μ receptor 6DDE
TM2 93 2.63x63 μ receptor 6DDE - -
TM2 94 2.64x64 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 95 2.65x65 μ receptor 6DDE P2Y12 receptor 4NTJ
TM2 96 2.66x66 μ receptor 6DDE apelin receptor 5VBL
TM2 97 2.67x67 C5a1 receptor 5O9H μ receptor 6DDE
ECL1 98 - - - -
ECL1 99 23.49x49 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 100 23.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 101 23.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 102 23.52x52 - - - -
TM3 103 3.21x21 μ receptor 6DDE μ receptor 6DDE
TM3 104 3.22x22 μ receptor 6DDE FFA1 receptor 5TZY
TM3 105 3.23x23 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM3 106 3.24x24 μ receptor 6DDE NTS1 receptor 4XES
TM3 107 3.25x25 μ receptor 6DDE μ receptor 6DDE
TM3 108 3.26x26 μ receptor 6DDE PAR1 3VW7
TM3 109 3.27x27 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 110 3.28x28 μ receptor 6DDE PAR2 5NDD
TM3 111 3.29x29 μ receptor 6DDE C5a1 receptor 5O9H
TM3 112 3.30x30 μ receptor 6DDE μ receptor 6DDE
TM3 113 3.31x31 μ receptor 6DDE μ receptor 6DDE
TM3 114 3.32x32 μ receptor 6DDE C5a1 receptor 5O9H
TM3 115 3.33x33 μ receptor 6DDE A2A receptor 4UHR
TM3 116 3.34x34 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 117 3.35x35 μ receptor 6DDE P2Y12 receptor 4NTJ
TM3 118 3.36x36 μ receptor 6DDE μ receptor 6DDE
TM3 119 3.37x37 μ receptor 6DDE PAR1 3VW7
TM3 120 3.38x38 μ receptor 6DDE PAR1 3VW7
TM3 121 3.39x39 μ receptor 6DDE μ receptor 6DDE
TM3 122 3.40x40 μ receptor 6DDE PAF receptor 5ZKQ
TM3 123 3.41x41 μ receptor 6DDE PAR1 3VW7
TM3 124 3.42x42 μ receptor 6DDE PAR1 3VW7
TM3 125 3.43x43 μ receptor 6DDE μ receptor 6DDE
TM3 126 3.44x44 μ receptor 6DDE NTS1 receptor 4XES
TM3 127 3.45x45 μ receptor 6DDE FFA1 receptor 5TZY
TM3 128 3.46x46 μ receptor 6DDE PAR2 5NDD
TM3 129 3.47x47 μ receptor 6DDE μ receptor 6DDE
TM3 130 3.48x48 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 131 3.49x49 μ receptor 6DDE μ receptor 6DDE
TM3 132 3.50x50 μ receptor 6DDE NTS1 receptor 4BUO
TM3 133 3.51x51 μ receptor 6DDE - -
TM3 134 3.52x52 μ receptor 6DDE M4 receptor 5DSG
TM3 135 3.53x53 μ receptor 6DDE C5a1 receptor 5O9H
TM3 136 3.54x54 μ receptor 6DDE FFA1 receptor 5TZY
TM3 137 3.55x55 μ receptor 6DDE - -
TM3 138 3.56x56 μ receptor 6DDE - -
ICL2 139 34.50x50 - - - -
ICL2 140 34.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 141 34.52x52 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 142 34.53x53 C5a1 receptor 5O9H - -
ICL2 143 34.54x54 C5a1 receptor 5O9H 5-HT1B receptor 4IAQ
ICL2 144 34.55x55 C5a1 receptor 5O9H NTS1 receptor 4XES
ICL2 145 34.56x56 C5a1 receptor 5O9H BLT1 receptor 5X33
ICL2 146 34.57x57 - - - -
TM4 147 4.38x38 μ receptor 6DDE FFA1 receptor 5TZY
TM4 148 4.39x39 μ receptor 6DDE PAR2 5NDD
TM4 149 4.40x40 μ receptor 6DDE FFA1 receptor 5TZY
TM4 150 4.41x41 μ receptor 6DDE P2Y12 receptor 4NTJ
TM4 151 4.42x42 μ receptor 6DDE D2 receptor 6CM4
TM4 152 4.43x43 μ receptor 6DDE NOP receptor 5DHG
TM4 153 4.44x44 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM4 154 4.45x45 μ receptor 6DDE C5a1 receptor 6C1R
TM4 155 4.46x46 μ receptor 6DDE PAR1 3VW7
TM4 156 4.47x47 μ receptor 6DDE M1 receptor 5CXV
TM4 157 4.48x48 μ receptor 6DDE PAR1 3VW7
TM4 158 4.49x49 μ receptor 6DDE C5a1 receptor 5O9H
TM4 159 4.50x50 μ receptor 6DDE μ receptor 6DDE
TM4 160 4.51x51 μ receptor 6DDE LPA1 receptor 4Z35
TM4 161 4.52x52 μ receptor 6DDE μ receptor 6DDE
TM4 162 4.53x53 μ receptor 6DDE PAR1 3VW7
TM4 163 4.54x54 μ receptor 6DDE PAR2 5NDD
TM4 164 4.55x55 μ receptor 6DDE PAR2 5NDD
TM4 165 4.56x56 μ receptor 6DDE NTS1 receptor 4XES
TM4 166 4.57x57 C5a1 receptor 5O9H PAR2 5NDD
TM4 167 4.58x59 C5a1 receptor 5O9H PAR1 3VW7
TM4 168 4.59x60 μ receptor 6DDE PAR1 3VW7
TM4 169 4.60x61 μ receptor 6DDE C5a1 receptor 5O9H
TM4 170 4.61x62 μ receptor 6DDE C5a1 receptor 5O9H
TM4 171 4.62x63 C5a1 receptor 5O9H 5-HT2B receptor 4IB4
TM4 172 4.63x64 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 173 4.64x65 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 174 - - - -
ECL2 175 C5a1 receptor 5O9H - -
ECL2 176 C5a1 receptor 5O9H - -
ECL2 177 C5a1 receptor 5O9H - -
ECL2 178 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 179 C5a1 receptor 5O9H - -
ECL2 180 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 181 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL2 182 C5a1 receptor 5O9H - -
ECL2 183 C5a1 receptor 5O9H - -
ECL2 184 C5a1 receptor 5O9H - -
ECL2 185 - - - -
ECL2 186 45.50x50 μ receptor 6DDE μ receptor 6DDE
ECL2 187 45.51x51 μ receptor 6DDE 5-HT2B receptor 4IB4
ECL2 188 45.52x52 μ receptor 6DDE 5-HT1B receptor 4IAQ
ECL2 189 - - - -
ECL2 190 AT2 receptor 5UNH - -
ECL2 191 AT2 receptor 5UNH - -
ECL2 192 - - - -
TM5 193 5.31x32 C5a1 receptor 5O9H BLT1 receptor 5X33
TM5 194 5.32x33 C5a1 receptor 5O9H κ receptor 4DJH
TM5 195 5.33x34 μ receptor 6DDE LPA6 receptor 5XSZ
TM5 196 5.34x35 μ receptor 6DDE NTS1 receptor 4XES
TM5 197 5.35x36 μ receptor 6DDE μ receptor 6DDE
TM5 198 5.36x37 μ receptor 6DDE μ receptor 6DDE
TM5 199 5.37x38 μ receptor 6DDE C5a1 receptor 5O9H
TM5 200 5.38x39 μ receptor 6DDE NTS1 receptor 4XES
TM5 201 5.39x40 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM5 202 5.40x41 μ receptor 6DDE PAR1 3VW7
TM5 203 5.41x42 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 204 5.42x43 μ receptor 6DDE C5a1 receptor 5O9H
TM5 205 5.43x44 μ receptor 6DDE μ receptor 6DDE
TM5 206 5.44x45 μ receptor 6DDE FFA1 receptor 5TZY
TM5 207 5.45x46 μ receptor 6DDE μ receptor 6DDE
TM5 208 5.46x461 μ receptor 6DDE C5a1 receptor 5O9H
TM5 209 5.47x47 μ receptor 6DDE μ receptor 6DDE
TM5 210 5.48x48 μ receptor 6DDE PAR2 5NDD
TM5 211 5.49x49 μ receptor 6DDE Y1 receptor 5ZBH
TM5 212 5.50x50 μ receptor 6DDE μ receptor 6DDE
TM5 213 5.51x51 μ receptor 6DDE PAR1 3VW7
TM5 214 5.52x52 μ receptor 6DDE P2Y1 receptor 4XNW
TM5 215 5.53x53 μ receptor 6DDE - -
TM5 216 5.54x54 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 217 5.55x55 μ receptor 6DDE PAR2 5NDD
TM5 218 5.56x56 μ receptor 6DDE PAR2 5NDD
TM5 219 5.57x57 μ receptor 6DDE μ receptor 6DDE
TM5 220 5.58x58 μ receptor 6DDE - -
TM5 221 5.59x59 μ receptor 6DDE CCR5 5UIW
TM5 222 5.60x60 μ receptor 6DDE D4 receptor 5WIV
TM5 223 5.61x61 μ receptor 6DDE Rhodopsin 4ZWJ
TM5 224 5.62x62 μ receptor 6DDE FFA1 receptor 5TZY
TM5 225 5.63x63 μ receptor 6DDE ETB receptor 5X93
TM5 226 5.64x64 μ receptor 6DDE - -
ICL3 227 - - - -
ICL3 228 - - - -
TM6 229 6.31x31 μ receptor 6DDE μ receptor 6DDE
TM6 230 6.32x32 μ receptor 6DDE μ receptor 6DDE
TM6 231 6.33x33 μ receptor 6DDE - -
TM6 232 6.34x34 μ receptor 6DDE FFA1 receptor 5KW2
TM6 233 6.35x35 μ receptor 6DDE - -
TM6 234 6.36x36 μ receptor 6DDE CCR5 5UIW
TM6 235 6.37x37 μ receptor 6DDE - -
TM6 236 6.38x38 μ receptor 6DDE - -
TM6 237 6.39x39 μ receptor 6DDE PAR1 3VW7
TM6 238 6.40x40 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 239 6.41x41 μ receptor 6DDE μ receptor 6DDE
TM6 240 6.42x42 μ receptor 6DDE apelin receptor 5VBL
TM6 241 6.43x43 μ receptor 6DDE - -
TM6 242 6.44x44 μ receptor 6DDE μ receptor 6DDE
TM6 243 6.45x45 μ receptor 6DDE PAR1 3VW7
TM6 244 6.46x46 μ receptor 6DDE NTS1 receptor 4XES
TM6 245 6.47x47 μ receptor 6DDE PAR1 3VW7
TM6 246 6.48x48 μ receptor 6DDE μ receptor 6DDE
TM6 247 6.49x49 μ receptor 6DDE CCR5 5UIW
TM6 248 6.50x50 μ receptor 6DDE μ receptor 6DDE
TM6 249 6.51x51 μ receptor 6DDE NTS1 receptor 4XES
TM6 250 6.52x52 μ receptor 6DDE μ receptor 6DDE
TM6 251 6.53x53 μ receptor 6DDE PAR2 5NDD
TM6 252 6.54x54 μ receptor 6DDE PAR1 3VW7
TM6 253 6.55x55 μ receptor 6DDE FFA1 receptor 5KW2
TM6 254 6.56x56 μ receptor 6DDE NTS1 receptor 4XES
TM6 255 6.57x57 μ receptor 6DDE PAR2 5NDD
TM6 256 6.58x58 μ receptor 6DDE FFA1 receptor 5KW2
TM6 257 6.59x59 μ receptor 6DDE P2Y12 receptor 4NTJ
TM6 258 6.60x60 μ receptor 6DDE OX1 receptor 4ZJ8
TM6 259 6.61x61 μ receptor 6DDE - -
ECL3 260 - - - -
ECL3 261 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL3 262 - - - -
TM7 263 7.25x24 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 264 7.26x25 C5a1 receptor 5O9H P2Y1 receptor 4XNW
TM7 265 7.27x26 C5a1 receptor 5O9H NTS1 receptor 4XES
TM7 266 7.28x27 C5a1 receptor 5O9H ETB receptor 5X93
TM7 267 7.29x28 C5a1 receptor 5O9H AT2 receptor 5UNG
TM7 268 7.30x29 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 269 7.31x30 μ receptor 6DDE PAR1 3VW7
TM7 270 7.32x31 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM7 271 7.33x32 μ receptor 6DDE US28 4XT1
TM7 272 7.34x33 μ receptor 6DDE PAR1 3VW7
TM7 273 7.35x34 μ receptor 6DDE LPA1 receptor 4Z35
TM7 274 7.36x35 μ receptor 6DDE AT1 receptor 4ZUD
TM7 275 7.37x36 μ receptor 6DDE PAR1 3VW7
TM7 276 7.38x37 μ receptor 6DDE - -
TM7 277 7.39x38 μ receptor 6DDE PAR1 3VW7
TM7 278 7.40x39 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 279 7.41x40 μ receptor 6DDE μ receptor 6DDE
TM7 280 7.42x41 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 281 7.43x42 μ receptor 6DDE CB1 receptor 5XRA
TM7 282 7.44x43 μ receptor 6DDE NTS1 receptor 4XES
TM7 283 7.45x45 μ receptor 6DDE CXCR4 3ODU
TM7 284 7.46x46 μ receptor 6DDE μ receptor 6DDE
TM7 285 7.47x47 μ receptor 6DDE μ receptor 6DDE
TM7 286 7.48x48 μ receptor 6DDE μ receptor 6DDE
TM7 287 7.49x49 μ receptor 6DDE μ receptor 6DDE
TM7 288 7.50x50 μ receptor 6DDE μ receptor 6DDE
TM7 289 7.51x51 μ receptor 6DDE M1 receptor 5CXV
TM7 290 7.52x52 μ receptor 6DDE μ receptor 6DDE
TM7 291 7.53x53 μ receptor 6DDE - -
TM7 292 7.54x54 μ receptor 6DDE - -
TM7 293 7.55x55 C5a1 receptor 5O9H A2A receptor 4UHR
TM7 294 7.56x56 C5a1 receptor 5O9H 5-HT2B receptor 4IB4
H8 295 8.47x47 CCR9 5LWE CCR9 5LWE
H8 296 8.48x48 CCR9 5LWE A2A receptor 4UHR
H8 297 8.49x49 CCR9 5LWE M1 receptor 5CXV
H8 298 8.50x50 CCR9 5LWE - -
H8 299 8.51x51 CCR9 5LWE - -
H8 300 8.52x52 CCR9 5LWE CCR9 5LWE
H8 301 8.53x53 CCR9 5LWE - -
H8 302 8.54x54 CCR9 5LWE - -
H8 303 8.55x55 CCR9 5LWE CCR5 5UIW
H8 304 8.56x56 CCR9 5LWE - -
C-term 305 - - - -
C-term 306 - - - -
C-term 307 - - - -
C-term 308 - - - -
C-term 309 - - - -