CCR2 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 5.84 docs)

VERSION

2018-07-10

MAIN TEMPLATE

AT2 receptor (sequence similarity: 50%) PDB: 5UNG

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 75.5 17.0 7.5
Side-chains 23.8 63.6 12.6

Number of backbone templates: 4
Number of rotamer templates: 20

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5T1A
5UNG
4ZUD
5UIW
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 32 - - - -
N-term 33 - - - -
N-term 34 - - - -
N-term 35 - - - -
N-term 36 - - - -
TM1 37 1.27x27 CCR2 5T1A CCR2 5T1A
TM1 38 1.28x28 CCR2 5T1A CCR5 5UIW
TM1 39 1.29x29 CCR2 5T1A CCR5 5UIW
TM1 40 1.30x30 CCR2 5T1A CCR2 5T1A
TM1 41 1.31x31 CCR2 5T1A CCR2 5T1A
TM1 42 1.32x32 CCR2 5T1A CCR2 5T1A
TM1 43 1.33x33 AT2 receptor 5UNG - -
TM1 44 1.34x34 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM1 45 1.35x35 AT2 receptor 5UNG Rhodopsin 5DYS
TM1 46 1.36x36 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 47 1.37x37 AT2 receptor 5UNG CCR2 5T1A
TM1 48 1.38x38 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 49 1.39x39 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 50 1.40x40 AT2 receptor 5UNG κ receptor 6B73
TM1 51 1.41x41 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM1 52 1.42x42 AT2 receptor 5UNG US28 4XT1
TM1 53 1.43x43 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 54 1.44x44 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM1 55 1.45x45 AT2 receptor 5UNG US28 4XT1
TM1 56 1.46x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 57 1.47x47 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 58 1.48x48 AT2 receptor 5UNG κ receptor 6B73
TM1 59 1.49x49 AT2 receptor 5UNG US28 4XT1
TM1 60 1.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 61 1.51x51 AT2 receptor 5UNG CCR2 5T1A
TM1 62 1.52x52 AT2 receptor 5UNG US28 4XT1
TM1 63 1.53x53 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 64 1.54x54 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 65 1.55x55 AT2 receptor 5UNG 5-HT2B receptor 5TUD
TM1 66 1.56x56 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM1 67 1.57x57 AT2 receptor 5UNG CCR2 5T1A
TM1 68 1.58x58 AT2 receptor 5UNG κ receptor 6B73
TM1 69 1.59x59 AT2 receptor 5UNG CCR2 5T1A
TM1 70 1.60x60 CCR2 5T1A CCR2 5T1A
ICL1 71 12.48x48 - - - -
ICL1 72 12.49x49 AT1 receptor 4ZUD 5-HT2C receptor 6BQG
ICL1 73 12.50x50 AT1 receptor 4ZUD AT1 receptor 4ZUD
ICL1 74 12.51x51 - - - -
TM2 75 2.37x37 CCR2 5T1A CCR2 5T1A
TM2 76 2.38x38 AT2 receptor 5UNG CCR2 5T1A
TM2 77 2.39x39 AT2 receptor 5UNG κ receptor 6B73
TM2 78 2.40x40 AT2 receptor 5UNG US28 4XT1
TM2 79 2.41x41 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 80 2.42x42 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 81 2.43x43 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM2 82 2.44x44 AT2 receptor 5UNG Rhodopsin 5DYS
TM2 83 2.45x45 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 84 2.46x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 85 2.47x47 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 86 2.48x48 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM2 87 2.49x49 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM2 88 2.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 89 2.51x51 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 90 2.52x52 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 91 2.53x53 AT2 receptor 5UNG US28 4XT1
TM2 92 2.54x54 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 93 2.55x55 AT2 receptor 5UNG PAF receptor 5ZKP
TM2 94 2.56x56 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 95 2.57x57 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 96 2.58x58 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 97 2.59x59 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 98 2.60x60 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 99 2.61x61 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 100 2.62x62 AT2 receptor 5UNG CCR2 5T1A
TM2 101 2.63x63 AT2 receptor 5UNG CCR2 5T1A
TM2 102 2.64x64 AT2 receptor 5UNG CCR2 5T1A
TM2 103 2.65x65 AT2 receptor 5UNG CCR2 5T1A
TM2 104 2.66x66 AT2 receptor 5UNG PAF receptor 5ZKP
ECL1 105 23.49x49 - - - -
ECL1 106 23.50x50 CCR2 5T1A CCR2 5T1A
ECL1 107 23.51x51 CCR2 5T1A CCR2 5T1A
ECL1 108 23.52x52 - - - -
TM3 109 3.21x21 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 110 3.22x22 AT2 receptor 5UNG μ receptor 5C1M
TM3 111 3.23x23 AT2 receptor 5UNG NTS1 receptor 5T04
TM3 112 3.24x24 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 113 3.25x25 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 114 3.26x26 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 115 3.27x27 AT2 receptor 5UNG US28 4XT1
TM3 116 3.28x28 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 117 3.29x29 AT2 receptor 5UNG US28 4XT1
TM3 118 3.30x30 AT2 receptor 5UNG CB1 receptor 5XRA
TM3 119 3.31x31 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM3 120 3.32x32 AT2 receptor 5UNG CCR2 5T1A
TM3 121 3.33x33 AT2 receptor 5UNG CCR2 5T1A
TM3 122 3.34x34 AT2 receptor 5UNG PAF receptor 5ZKP
TM3 123 3.35x35 AT2 receptor 5UNG Rhodopsin 5DYS
TM3 124 3.36x36 AT2 receptor 5UNG CCR2 5T1A
TM3 125 3.37x37 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 126 3.38x38 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM3 127 3.39x39 AT2 receptor 5UNG CCR2 5T1A
TM3 128 3.40x40 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 129 3.41x41 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 130 3.42x42 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 131 3.43x43 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 132 3.44x44 AT2 receptor 5UNG CCR2 5T1A
TM3 133 3.45x45 AT2 receptor 5UNG CB1 receptor 5XRA
TM3 134 3.46x46 AT2 receptor 5UNG Rhodopsin 5DYS
TM3 135 3.47x47 AT2 receptor 5UNG PAF receptor 5ZKP
TM3 136 3.48x48 AT2 receptor 5UNG Rhodopsin 5DYS
TM3 137 3.49x49 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 138 3.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 139 3.51x51 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 140 3.52x52 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM3 141 3.53x53 AT2 receptor 5UNG US28 4XT1
TM3 142 3.54x54 AT2 receptor 5UNG US28 4XT1
TM3 143 3.55x55 AT2 receptor 5UNG US28 4XT1
TM3 144 3.56x56 AT2 receptor 5UNG κ receptor 6B73
ICL2 145 34.50x50 - - - -
ICL2 146 34.51x51 CCR2 5T1A CCR2 5T1A
ICL2 147 34.52x52 CCR2 5T1A CCR2 5T1A
ICL2 148 34.53x53 CCR2 5T1A CCR2 5T1A
ICL2 149 34.54x54 CCR2 5T1A CCR2 5T1A
ICL2 150 34.55x55 CCR2 5T1A BLT1 receptor 5X33
ICL2 151 34.56x56 CCR2 5T1A CCR2 5T1A
ICL2 152 34.57x57 - - - -
TM4 153 4.38x38 CCR2 5T1A CCR2 5T1A
TM4 154 4.39x39 CCR2 5T1A CCR2 5T1A
TM4 155 4.40x40 CCR2 5T1A CCR2 5T1A
TM4 156 4.41x41 AT2 receptor 5UNG CCR2 5T1A
TM4 157 4.42x42 AT2 receptor 5UNG CCR2 5T1A
TM4 158 4.43x43 AT2 receptor 5UNG CB1 receptor 5XRA
TM4 159 4.44x44 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM4 160 4.45x45 AT2 receptor 5UNG CCR2 5T1A
TM4 161 4.46x46 AT2 receptor 5UNG US28 4XT1
TM4 162 4.47x47 AT2 receptor 5UNG μ receptor 5C1M
TM4 163 4.48x48 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM4 164 4.49x49 AT2 receptor 5UNG Rhodopsin 5DYS
TM4 165 4.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 166 4.51x51 AT2 receptor 5UNG κ receptor 6B73
TM4 167 4.52x52 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM4 168 4.53x53 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 169 4.54x54 AT2 receptor 5UNG US28 4XT1
TM4 170 4.55x55 AT2 receptor 5UNG CCR2 5T1A
TM4 171 4.56x56 AT2 receptor 5UNG PAF receptor 5ZKP
TM4 172 4.57x57 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 173 4.58x59 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM4 174 4.59x60 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 175 4.60x61 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM4 176 4.61x62 AT2 receptor 5UNG PAF receptor 5ZKP
TM4 177 4.62x63 AT2 receptor 5UNG 5-HT2B receptor 5TUD
TM4 178 4.63x64 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 179 4.64x65 AT2 receptor 5UNG CCR2 5T1A
ECL2 180 - - - -
ECL2 181 CCR5 5UIW - -
ECL2 182 CCR5 5UIW CCR5 5UIW
ECL2 183 CCR5 5UIW CCR5 5UIW
ECL2 184 CCR5 5UIW CCR5 5UIW
ECL2 185 CCR5 5UIW - -
ECL2 186 CCR5 5UIW - -
ECL2 187 CCR5 5UIW - -
ECL2 188 CCR5 5UIW CCR5 5UIW
ECL2 189 - - - -
ECL2 190 45.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
ECL2 191 45.51x51 AT2 receptor 5UNG Rhodopsin 5DYS
ECL2 192 45.52x52 AT2 receptor 5UNG NTS1 receptor 5T04
ECL2 193 - - - -
ECL2 194 - - - -
TM5 195 5.31x32 AT2 receptor 5UNG - -
TM5 196 5.32x33 AT2 receptor 5UNG - -
TM5 197 5.33x34 AT2 receptor 5UNG CCR2 5T1A
TM5 198 5.34x35 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 199 5.35x36 AT2 receptor 5UNG Rhodopsin 5DYS
TM5 200 5.36x37 AT2 receptor 5UNG μ receptor 5C1M
TM5 201 5.37x38 AT2 receptor 5UNG κ receptor 6B73
TM5 202 5.38x39 AT2 receptor 5UNG CCR2 5T1A
TM5 203 5.39x40 AT2 receptor 5UNG M2 receptor 4MQT
TM5 204 5.40x41 AT2 receptor 5UNG κ receptor 6B73
TM5 205 5.41x42 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 206 5.42x43 AT2 receptor 5UNG CCR2 5T1A
TM5 207 5.43x44 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 208 5.44x45 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 209 5.45x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 210 5.46x461 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 211 5.47x47 AT2 receptor 5UNG CCR2 5T1A
TM5 212 5.48x48 AT2 receptor 5UNG US28 4XT1
TM5 213 5.49x49 AT2 receptor 5UNG PAF receptor 5ZKP
TM5 214 5.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 215 5.51x51 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 216 5.52x52 AT2 receptor 5UNG κ receptor 6B73
TM5 217 5.53x53 AT2 receptor 5UNG κ receptor 6B73
TM5 218 5.54x54 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM5 219 5.55x55 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM5 220 5.56x56 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM5 221 5.57x57 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 222 5.58x58 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 223 5.59x59 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM5 224 5.60x60 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 225 5.61x61 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 226 5.62x62 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM5 227 5.63x63 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 228 5.64x64 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM5 229 5.65x65 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 230 5.66x66 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 231 5.67x67 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM5 232 5.68x68 AT2 receptor 5UNG - -
ICL3 233 AT2 receptor 5UNG - -
ICL3 234 AT2 receptor 5UNG - -
ICL3 235 AT2 receptor 5UNG - -
TM6 236 6.28x28 AT2 receptor 5UNG Rhodopsin 5DYS
TM6 237 6.29x29 AT2 receptor 5UNG β2-adrenoceptor 4LDE
TM6 238 6.30x30 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 239 6.31x31 AT2 receptor 5UNG β2-adrenoceptor 4LDE
TM6 240 6.32x32 AT2 receptor 5UNG US28 4XT1
TM6 241 6.33x33 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM6 242 6.34x34 AT2 receptor 5UNG US28 4XT1
TM6 243 6.35x35 AT2 receptor 5UNG US28 4XT1
TM6 244 6.36x36 AT2 receptor 5UNG US28 4XT1
TM6 245 6.37x37 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM6 246 6.38x38 AT2 receptor 5UNG CCR2 5T1A
TM6 247 6.39x39 AT2 receptor 5UNG CCR2 5T1A
TM6 248 6.40x40 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM6 249 6.41x41 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM6 250 6.42x42 AT2 receptor 5UNG Rhodopsin 5DYS
TM6 251 6.43x43 AT2 receptor 5UNG US28 4XT1
TM6 252 6.44x44 AT2 receptor 5UNG CCR2 5T1A
TM6 253 6.45x45 AT2 receptor 5UNG PAF receptor 5ZKP
TM6 254 6.46x46 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM6 255 6.47x47 AT2 receptor 5UNG US28 4XT1
TM6 256 6.48x48 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 257 6.49x49 AT2 receptor 5UNG κ receptor 6B73
TM6 258 6.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 259 6.51x51 AT2 receptor 5UNG US28 4XT1
TM6 260 6.52x52 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM6 261 6.53x53 AT2 receptor 5UNG κ receptor 6B73
TM6 262 6.54x54 AT2 receptor 5UNG PAF receptor 5ZKP
TM6 263 6.55x55 AT2 receptor 5UNG κ receptor 6B73
TM6 264 6.56x56 AT2 receptor 5UNG κ receptor 6B73
TM6 265 6.57x57 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 266 6.58x58 AT2 receptor 5UNG M2 receptor 4MQT
TM6 267 6.59x59 AT2 receptor 5UNG US28 4XT1
TM6 268 6.60x60 AT2 receptor 5UNG M2 receptor 4MQT
TM6 269 6.61x61 AT2 receptor 5UNG CCR2 5T1A
TM6 270 6.62x62 AT2 receptor 5UNG PAF receptor 5ZKP
TM6 271 6.63x63 AT2 receptor 5UNG - -
TM6 272 6.64x64 AT2 receptor 5UNG CCR2 5T1A
TM6 273 6.65x65 CCR2 5T1A CCR2 5T1A
ECL3 274 - - - -
ECL3 275 - - - -
TM7 276 7.24x23 AT2 receptor 5UNG CCR5 5UIW
TM7 277 7.25x24 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 278 7.26x25 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 279 7.27x26 AT2 receptor 5UNG CCR2 5T1A
TM7 280 7.28x27 AT2 receptor 5UNG CCR2 5T1A
TM7 281 7.29x28 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM7 282 7.30x29 AT2 receptor 5UNG CCR2 5T1A
TM7 283 7.31x30 AT2 receptor 5UNG US28 4XT1
TM7 284 7.32x31 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 285 7.33x32 AT2 receptor 5UNG CCR5 5UIW
TM7 286 7.34x33 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 287 7.35x34 AT2 receptor 5UNG A1 receptor 6D9H
TM7 288 7.36x35 AT2 receptor 5UNG PAF receptor 5ZKP
TM7 289 7.37x36 AT2 receptor 5UNG PAF receptor 5ZKP
TM7 290 7.38x37 AT2 receptor 5UNG US28 4XT1
TM7 291 7.39x38 AT2 receptor 5UNG US28 4XT1
TM7 292 7.40x39 AT2 receptor 5UNG CCR2 5T1A
TM7 293 7.41x40 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 294 7.42x41 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 295 7.43x42 AT2 receptor 5UNG CCR2 5T1A
TM7 296 7.44x43 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 297 7.45x45 AT2 receptor 5UNG US28 4XT1
TM7 298 7.46x46 AT2 receptor 5UNG US28 4XT1
TM7 299 7.47x47 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 300 7.48x48 AT2 receptor 5UNG 5-HT2C receptor 6BQG
TM7 301 7.49x49 CCR2 5T1A CCR2 5T1A
TM7 302 7.50x50 CCR2 5T1A CCR2 5T1A
TM7 303 7.51x51 CCR2 5T1A CCR2 5T1A
TM7 304 7.52x52 CCR2 5T1A CCR2 5T1A
TM7 305 7.53x53 CCR2 5T1A CCR2 5T1A
TM7 306 7.54x54 CCR2 5T1A CCR2 5T1A
TM7 307 7.55x55 CCR2 5T1A CCR2 5T1A
TM7 308 7.56x56 CCR2 5T1A CCR2 5T1A
H8 309 8.47x47 CCR2 5T1A CCR2 5T1A
H8 310 8.48x48 CCR2 5T1A CCR2 5T1A
H8 311 8.49x49 CCR2 5T1A CCR2 5T1A
H8 312 8.50x50 CCR2 5T1A CCR2 5T1A
H8 313 8.51x51 CCR2 5T1A US28 4XT1
H8 314 8.52x52 CCR2 5T1A - -
H8 315 8.53x53 CCR2 5T1A - -
H8 316 8.54x54 CCR2 5T1A β2-adrenoceptor 3SN6
H8 317 8.55x55 CCR2 5T1A US28 4XT1
H8 318 8.56x56 CCR2 5T1A - -
H8 319 8.57x57 CCR2 5T1A PAR2 5NDD
H8 320 8.58x58 CCR2 5T1A US28 4XT1
C-term 321 - - - -
C-term 322 - - - -
C-term 323 - - - -
C-term 324 - - - -
C-term 325 - - - -