CCR3 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 7.25 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 51%) PDB: 6DDE

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 75.5 18.9 5.6
Side-chains 20.5 61.6 17.9

Number of backbone templates: 4
Number of rotamer templates: 34

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5UIW
4MBS
6DDE
4ZUD
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 21 CCR5 5UIW CCR5 5UIW
N-term 22 CCR5 5UIW CCR5 5UIW
N-term 23 CCR5 5UIW CCR5 5UIW
N-term 24 CCR5 5UIW CCR5 5UIW
N-term 25 CCR5 5UIW CCR5 5UIW
TM1 26 1.24x24 CCR5 5UIW - -
TM1 27 1.25x25 CCR5 5UIW - -
TM1 28 1.26x26 CCR5 5UIW US28 4XT1
TM1 29 1.27x27 CCR5 5UIW - -
TM1 30 1.28x28 CCR5 5UIW CCR9 5LWE
TM1 31 1.29x29 CCR5 5UIW - -
TM1 32 1.30x30 CCR5 5UIW PAR2 5NDD
TM1 33 1.31x31 μ receptor 6DDE Y1 receptor 5ZBH
TM1 34 1.32x32 μ receptor 6DDE μ receptor 6DDE
TM1 35 1.33x33 μ receptor 6DDE FFA1 receptor 5TZR
TM1 36 1.34x34 μ receptor 6DDE PAR1 3VW7
TM1 37 1.35x35 μ receptor 6DDE PAR1 3VW7
TM1 38 1.36x36 μ receptor 6DDE PAR1 3VW7
TM1 39 1.37x37 μ receptor 6DDE CCR5 5UIW
TM1 40 1.38x38 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 41 1.39x39 μ receptor 6DDE μ receptor 6DDE
TM1 42 1.40x40 μ receptor 6DDE μ receptor 6DDE
TM1 43 1.41x41 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 44 1.42x42 μ receptor 6DDE μ receptor 6DDE
TM1 45 1.43x43 μ receptor 6DDE PAR1 3VW7
TM1 46 1.44x44 μ receptor 6DDE CB1 receptor 5XRA
TM1 47 1.45x45 μ receptor 6DDE μ receptor 6DDE
TM1 48 1.46x46 μ receptor 6DDE μ receptor 6DDE
TM1 49 1.47x47 μ receptor 6DDE PAR1 3VW7
TM1 50 1.48x48 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 51 1.49x49 μ receptor 6DDE μ receptor 6DDE
TM1 52 1.50x50 μ receptor 6DDE μ receptor 6DDE
TM1 53 1.51x51 μ receptor 6DDE A2A receptor 4UHR
TM1 54 1.52x52 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 55 1.53x53 μ receptor 6DDE μ receptor 6DDE
TM1 56 1.54x54 μ receptor 6DDE CCR2 5T1A
TM1 57 1.55x55 μ receptor 6DDE 5-HT2C receptor 6BQH
TM1 58 1.56x56 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 59 1.57x57 μ receptor 6DDE NTS1 receptor 4XES
TM1 60 1.58x58 μ receptor 6DDE PAR1 3VW7
TM1 61 1.59x59 μ receptor 6DDE ETB receptor 5X93
TM1 62 1.60x60 μ receptor 6DDE μ receptor 6DDE
ICL1 63 12.48x48 - - - -
ICL1 64 12.49x49 AT1 receptor 4ZUD β2-adrenoceptor 5JQH
ICL1 65 12.50x50 AT1 receptor 4ZUD AT1 receptor 4ZUD
ICL1 66 12.51x51 - - - -
TM2 67 2.37x37 CCR5 5UIW - -
TM2 68 2.38x38 μ receptor 6DDE CCR5 5UIW
TM2 69 2.39x39 μ receptor 6DDE μ receptor 6DDE
TM2 70 2.40x40 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 71 2.41x41 μ receptor 6DDE μ receptor 6DDE
TM2 72 2.42x42 μ receptor 6DDE μ receptor 6DDE
TM2 73 2.43x43 μ receptor 6DDE P2Y12 receptor 4NTJ
TM2 74 2.44x44 μ receptor 6DDE PAR1 3VW7
TM2 75 2.45x45 μ receptor 6DDE μ receptor 6DDE
TM2 76 2.46x46 μ receptor 6DDE μ receptor 6DDE
TM2 77 2.47x47 μ receptor 6DDE μ receptor 6DDE
TM2 78 2.48x48 μ receptor 6DDE P2Y12 receptor 4NTJ
TM2 79 2.49x49 μ receptor 6DDE P2Y12 receptor 4NTJ
TM2 80 2.50x50 μ receptor 6DDE μ receptor 6DDE
TM2 81 2.51x51 μ receptor 6DDE PAR2 5NDD
TM2 82 2.52x52 μ receptor 6DDE μ receptor 6DDE
TM2 83 2.53x53 μ receptor 6DDE PAR1 3VW7
TM2 84 2.54x54 μ receptor 6DDE PAF receptor 5ZKQ
TM2 85 2.55x55 μ receptor 6DDE A2A receptor 4UHR
TM2 86 2.56x56 μ receptor 6DDE μ receptor 6DDE
TM2 87 2.57x57 μ receptor 6DDE μ receptor 6DDE
TM2 88 2.58x58 μ receptor 6DDE μ receptor 6DDE
TM2 89 2.59x59 μ receptor 6DDE μ receptor 6DDE
TM2 90 2.60x60 μ receptor 6DDE PAF receptor 5ZKQ
TM2 91 2.61x61 μ receptor 6DDE PAR1 3VW7
TM2 92 2.62x62 μ receptor 6DDE CCR5 5UIW
TM2 93 2.63x63 μ receptor 6DDE PAR1 3VW7
TM2 94 2.64x64 μ receptor 6DDE - -
TM2 95 2.65x65 μ receptor 6DDE - -
TM2 96 2.66x66 μ receptor 6DDE A2A receptor 4UHR
ECL1 97 - - - -
ECL1 98 23.49x49 CCR5 5UIW PAR2 5NDD
ECL1 99 23.50x50 CCR5 5UIW CCR5 5UIW
ECL1 100 23.51x51 CCR5 5UIW CCR2 5T1A
ECL1 101 23.52x52 - - - -
TM3 102 3.21x21 μ receptor 6DDE μ receptor 6DDE
TM3 103 3.22x22 μ receptor 6DDE OX1 receptor 4ZJ8
TM3 104 3.23x23 μ receptor 6DDE - -
TM3 105 3.24x24 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 106 3.25x25 μ receptor 6DDE μ receptor 6DDE
TM3 107 3.26x26 μ receptor 6DDE μ receptor 6DDE
TM3 108 3.27x27 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 109 3.28x28 μ receptor 6DDE PAR2 5NDD
TM3 110 3.29x29 μ receptor 6DDE P2Y12 receptor 4NTJ
TM3 111 3.30x30 μ receptor 6DDE PAR2 5NDD
TM3 112 3.31x31 μ receptor 6DDE PAR2 5NDD
TM3 113 3.32x32 μ receptor 6DDE CCR5 5UIW
TM3 114 3.33x33 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 115 3.34x34 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM3 116 3.35x35 μ receptor 6DDE CCR5 5UIW
TM3 117 3.36x36 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 118 3.37x37 μ receptor 6DDE PAR1 3VW7
TM3 119 3.38x38 μ receptor 6DDE A2A receptor 4UHR
TM3 120 3.39x39 μ receptor 6DDE - -
TM3 121 3.40x40 μ receptor 6DDE μ receptor 6DDE
TM3 122 3.41x41 μ receptor 6DDE μ receptor 6DDE
TM3 123 3.42x42 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 124 3.43x43 μ receptor 6DDE CCR5 5UIW
TM3 125 3.44x44 μ receptor 6DDE CCR5 5UIW
TM3 126 3.45x45 μ receptor 6DDE P2Y12 receptor 4NTJ
TM3 127 3.46x46 μ receptor 6DDE PAR2 5NDD
TM3 128 3.47x47 μ receptor 6DDE PAF receptor 5ZKQ
TM3 129 3.48x48 μ receptor 6DDE PAR1 3VW7
TM3 130 3.49x49 μ receptor 6DDE μ receptor 6DDE
TM3 131 3.50x50 μ receptor 6DDE μ receptor 6DDE
TM3 132 3.51x51 μ receptor 6DDE μ receptor 6DDE
TM3 133 3.52x52 μ receptor 6DDE PAR1 3VW7
TM3 134 3.53x53 μ receptor 6DDE μ receptor 6DDE
TM3 135 3.54x54 μ receptor 6DDE PAR2 5NDD
TM3 136 3.55x55 μ receptor 6DDE PAR1 3VW7
TM3 137 3.56x56 μ receptor 6DDE μ receptor 6DDE
ICL2 138 34.50x50 - - - -
ICL2 139 34.51x51 CCR5 5UIW μ receptor 6DDE
ICL2 140 34.52x52 CCR5 5UIW CCR5 5UIW
ICL2 141 34.53x53 CCR5 5UIW CCR5 5UIW
ICL2 142 34.54x54 CCR5 5UIW μ receptor 6DDE
ICL2 143 34.55x55 CCR5 5UIW C5a1 receptor 5O9H
ICL2 144 34.56x56 CCR5 5UIW CCR5 5UIW
ICL2 145 34.57x57 - - - -
TM4 146 4.38x38 μ receptor 6DDE μ receptor 6DDE
TM4 147 4.39x39 μ receptor 6DDE CCR5 5UIW
TM4 148 4.40x40 μ receptor 6DDE A2A receptor 4UHR
TM4 149 4.41x41 μ receptor 6DDE CCR5 5UIW
TM4 150 4.42x42 μ receptor 6DDE PAF receptor 5ZKQ
TM4 151 4.43x43 μ receptor 6DDE CCR5 5UIW
TM4 152 4.44x44 μ receptor 6DDE μ receptor 6DDE
TM4 153 4.45x45 μ receptor 6DDE PAR1 3VW7
TM4 154 4.46x46 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 155 4.47x47 μ receptor 6DDE AT1 receptor 4ZUD
TM4 156 4.48x48 μ receptor 6DDE PAF receptor 5ZKQ
TM4 157 4.49x49 μ receptor 6DDE CCR5 5UIW
TM4 158 4.50x50 μ receptor 6DDE μ receptor 6DDE
TM4 159 4.51x51 μ receptor 6DDE C5a1 receptor 5O9H
TM4 160 4.52x52 μ receptor 6DDE μ receptor 6DDE
TM4 161 4.53x53 μ receptor 6DDE PAR1 3VW7
TM4 162 4.54x54 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 163 4.55x55 μ receptor 6DDE PAR2 5NDD
TM4 164 4.56x56 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 165 4.57x57 CCR5 5UIW PAF receptor 5ZKQ
TM4 166 4.58x59 CCR5 5UIW FFA1 receptor 5TZY
TM4 167 4.59x60 μ receptor 6DDE PAR1 3VW7
TM4 168 4.60x61 μ receptor 6DDE CCR9 5LWE
TM4 169 4.61x62 μ receptor 6DDE μ receptor 6DDE
TM4 170 4.62x63 CCR5 5UIW CCR5 5UIW
TM4 171 4.63x64 CCR5 5UIW CCR5 5UIW
TM4 172 4.64x65 CCR5 5UIW - -
ECL2 173 μ receptor 6DDE - -
ECL2 174 μ receptor 6DDE μ receptor 6DDE
ECL2 175 μ receptor 6DDE - -
ECL2 176 μ receptor 6DDE - -
ECL2 177 μ receptor 6DDE - -
ECL2 178 μ receptor 6DDE - -
ECL2 179 μ receptor 6DDE - -
ECL2 180 μ receptor 6DDE - -
ECL2 181 μ receptor 6DDE - -
ECL2 182 μ receptor 6DDE - -
ECL2 183 45.50x50 μ receptor 6DDE μ receptor 6DDE
ECL2 184 45.51x51 μ receptor 6DDE CCR5 5UIW
ECL2 185 45.52x52 μ receptor 6DDE BLT1 receptor 5X33
ECL2 186 μ receptor 6DDE - -
ECL2 187 μ receptor 6DDE - -
ECL2 188 μ receptor 6DDE - -
ECL2 189 μ receptor 6DDE - -
ECL2 190 μ receptor 6DDE - -
TM5 191 5.30x31 CCR5 5UIW - -
TM5 192 5.31x32 CCR5 5UIW - -
TM5 193 5.32x33 CCR5 5UIW - -
TM5 194 5.33x34 μ receptor 6DDE US28 4XT1
TM5 195 5.34x35 μ receptor 6DDE μ receptor 6DDE
TM5 196 5.35x36 μ receptor 6DDE Y1 receptor 5ZBH
TM5 197 5.36x37 μ receptor 6DDE - -
TM5 198 5.37x38 μ receptor 6DDE CCR5 5UIW
TM5 199 5.38x39 μ receptor 6DDE CCR2 5T1A
TM5 200 5.39x40 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM5 201 5.40x41 μ receptor 6DDE PAR2 5NDD
TM5 202 5.41x42 μ receptor 6DDE - -
TM5 203 5.42x43 μ receptor 6DDE Rhodopsin 5DYS
TM5 204 5.43x44 μ receptor 6DDE P2Y1 receptor 4XNW
TM5 205 5.44x45 μ receptor 6DDE PAR2 5NDD
TM5 206 5.45x46 μ receptor 6DDE μ receptor 6DDE
TM5 207 5.46x461 μ receptor 6DDE A2A receptor 4UHR
TM5 208 5.47x47 μ receptor 6DDE CCR5 5UIW
TM5 209 5.48x48 μ receptor 6DDE CCR5 5UIW
TM5 210 5.49x49 μ receptor 6DDE PAF receptor 5ZKQ
TM5 211 5.50x50 μ receptor 6DDE μ receptor 6DDE
TM5 212 5.51x51 μ receptor 6DDE PAR1 3VW7
TM5 213 5.52x52 μ receptor 6DDE PAF receptor 5ZKQ
TM5 214 5.53x53 μ receptor 6DDE NTS1 receptor 4XES
TM5 215 5.54x54 μ receptor 6DDE 5-HT2B receptor 4IB4
TM5 216 5.55x55 μ receptor 6DDE PAR2 5NDD
TM5 217 5.56x56 μ receptor 6DDE NTS1 receptor 4XES
TM5 218 5.57x57 μ receptor 6DDE μ receptor 6DDE
TM5 219 5.58x58 μ receptor 6DDE μ receptor 6DDE
TM5 220 5.59x59 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 221 5.60x60 μ receptor 6DDE FFA1 receptor 5TZY
TM5 222 5.61x61 μ receptor 6DDE PAR1 3VW7
TM5 223 5.62x62 μ receptor 6DDE μ receptor 6DDE
TM5 224 5.63x63 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 225 5.64x64 μ receptor 6DDE PAF receptor 5ZKQ
TM5 226 5.65x65 μ receptor 6DDE μ receptor 6DDE
TM5 227 5.66x66 μ receptor 6DDE PAF receptor 5ZKQ
TM5 228 5.67x67 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 229 5.68x68 μ receptor 6DDE - -
ICL3 230 - - - -
ICL3 231 - - - -
ICL3 232 - - - -
ICL3 233 - - - -
TM6 234 6.30x30 μ receptor 6DDE PAR1 3VW7
TM6 235 6.31x31 μ receptor 6DDE - -
TM6 236 6.32x32 μ receptor 6DDE PAR2 5NDD
TM6 237 6.33x33 μ receptor 6DDE 5-HT2B receptor 4IB4
TM6 238 6.34x34 μ receptor 6DDE - -
TM6 239 6.35x35 μ receptor 6DDE μ receptor 6DDE
TM6 240 6.36x36 μ receptor 6DDE CCR5 5UIW
TM6 241 6.37x37 μ receptor 6DDE CCR5 5UIW
TM6 242 6.38x38 μ receptor 6DDE CCR5 5UIW
TM6 243 6.39x39 μ receptor 6DDE μ receptor 6DDE
TM6 244 6.40x40 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 245 6.41x41 μ receptor 6DDE CCR5 5UIW
TM6 246 6.42x42 μ receptor 6DDE μ receptor 6DDE
TM6 247 6.43x43 μ receptor 6DDE μ receptor 6DDE
TM6 248 6.44x44 μ receptor 6DDE μ receptor 6DDE
TM6 249 6.45x45 μ receptor 6DDE PAR1 3VW7
TM6 250 6.46x46 μ receptor 6DDE PAR1 3VW7
TM6 251 6.47x47 μ receptor 6DDE CCR5 5UIW
TM6 252 6.48x48 μ receptor 6DDE μ receptor 6DDE
TM6 253 6.49x49 μ receptor 6DDE PAR2 5NDD
TM6 254 6.50x50 μ receptor 6DDE μ receptor 6DDE
TM6 255 6.51x51 μ receptor 6DDE NTS1 receptor 4XES
TM6 256 6.52x52 μ receptor 6DDE PAR1 3VW7
TM6 257 6.53x53 μ receptor 6DDE PAR1 3VW7
TM6 258 6.54x54 μ receptor 6DDE P2Y12 receptor 4NTJ
TM6 259 6.55x55 μ receptor 6DDE CCR2 5T1A
TM6 260 6.56x56 μ receptor 6DDE PAF receptor 5ZKQ
TM6 261 6.57x57 μ receptor 6DDE CCR5 5UIW
TM6 262 6.58x58 μ receptor 6DDE FFA1 receptor 5TZY
TM6 263 6.59x59 μ receptor 6DDE CXCR4 3ODU
TM6 264 6.60x60 μ receptor 6DDE NTS1 receptor 4XES
TM6 265 6.61x61 μ receptor 6DDE β2-adrenoceptor 2RH1
TM6 266 6.62x62 CCR5 4MBS apelin receptor 5VBL
TM6 267 6.63x63 CCR5 4MBS - -
TM6 268 6.64x64 CCR5 4MBS - -
TM6 269 6.65x65 CCR5 4MBS - -
ECL3 270 - - - -
ECL3 271 - - - -
TM7 272 7.24x23 CCR5 5UIW PAF receptor 5ZKQ
TM7 273 7.25x24 CCR5 5UIW CCR5 5UIW
TM7 274 7.26x25 CCR5 5UIW CXCR4 3ODU
TM7 275 7.27x26 CCR5 5UIW - -
TM7 276 7.28x27 CCR5 5UIW CCR5 5UIW
TM7 277 7.29x28 CCR5 5UIW 5-HT2C receptor 6BQH
TM7 278 7.30x29 μ receptor 6DDE - -
TM7 279 7.31x30 μ receptor 6DDE P2Y12 receptor 4NTJ
TM7 280 7.32x31 μ receptor 6DDE CCR5 5UIW
TM7 281 7.33x32 μ receptor 6DDE AT2 receptor 5UNG
TM7 282 7.34x33 μ receptor 6DDE P2Y12 receptor 4NTJ
TM7 283 7.35x34 μ receptor 6DDE A2A receptor 4UHR
TM7 284 7.36x35 μ receptor 6DDE PAR1 3VW7
TM7 285 7.37x36 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 286 7.38x37 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 287 7.39x38 μ receptor 6DDE CCR5 5UIW
TM7 288 7.40x39 μ receptor 6DDE A2A receptor 4UHR
TM7 289 7.41x40 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 290 7.42x41 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 291 7.43x42 μ receptor 6DDE μ receptor 6DDE
TM7 292 7.44x43 μ receptor 6DDE LPA6 receptor 5XSZ
TM7 293 7.45x45 μ receptor 6DDE CCR5 5UIW
TM7 294 7.46x46 μ receptor 6DDE PAR1 3VW7
TM7 295 7.47x47 μ receptor 6DDE μ receptor 6DDE
TM7 296 7.48x48 μ receptor 6DDE A1 receptor 5UEN
TM7 297 7.49x49 μ receptor 6DDE μ receptor 6DDE
TM7 298 7.50x50 μ receptor 6DDE μ receptor 6DDE
TM7 299 7.51x51 μ receptor 6DDE μ receptor 6DDE
TM7 300 7.52x52 μ receptor 6DDE PAR1 3VW7
TM7 301 7.53x53 μ receptor 6DDE μ receptor 6DDE
TM7 302 7.54x54 μ receptor 6DDE μ receptor 6DDE
TM7 303 7.55x55 CCR5 5UIW CCR5 5UIW
TM7 304 7.56x56 CCR5 5UIW CCR5 5UIW
H8 305 8.47x47 CCR5 5UIW CCR5 5UIW
H8 306 8.48x48 CCR5 5UIW 5-HT1B receptor 4IAQ
H8 307 8.49x49 CCR5 5UIW CCR9 5LWE
H8 308 8.50x50 CCR5 5UIW PAR2 5NDD
H8 309 8.51x51 CCR5 5UIW PAR2 5NDD
H8 310 8.52x52 CCR5 5UIW H1 receptor 3RZE
H8 311 8.53x53 CCR5 5UIW CCR5 5UIW
H8 312 8.54x54 CCR5 5UIW CCR5 5UIW
H8 313 8.55x55 CCR5 5UIW A2A receptor 4UHR
H8 314 8.56x56 CCR5 5UIW M4 receptor 5DSG
H8 315 8.57x57 CCR5 5UIW CCR5 5UIW
H8 316 8.58x58 CCR5 5UIW CCR5 5UIW
H8 317 8.59x59 CCR5 5UIW H1 receptor 3RZE
C-term 318 - - - -
C-term 319 - - - -
C-term 320 - - - -
C-term 321 - - - -
C-term 322 - - - -