CCR4 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): 1.03 docs)

VERSION

2018-07-10

MAIN TEMPLATE

CCR5 (sequence similarity: 76%) PDB: 5UIW

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 92.0 2.3 5.7
Side-chains 48.0 37.7 14.3

Number of backbone templates: 4
Number of rotamer templates: 31

NGL is a WebGL based 3D viewer powered by MMTF.

5UIW
4MBS
4ZUD
4XT1
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 26 CCR5 5UIW CCR5 5UIW
N-term 27 CCR5 5UIW CCR5 5UIW
N-term 28 CCR5 5UIW CCR5 5UIW
N-term 29 CCR5 5UIW CCR5 5UIW
N-term 30 CCR5 5UIW CCR5 5UIW
TM1 31 1.24x24 CCR5 5UIW - -
TM1 32 1.25x25 CCR5 5UIW CXCR4 4RWS
TM1 33 1.26x26 CCR5 5UIW - -
TM1 34 1.27x27 CCR5 5UIW ETB receptor 5X93
TM1 35 1.28x28 CCR5 5UIW CCR5 5UIW
TM1 36 1.29x29 CCR5 5UIW - -
TM1 37 1.30x30 CCR5 5UIW CXCR4 3ODU
TM1 38 1.31x31 CCR5 5UIW CCR2 5T1A
TM1 39 1.32x32 CCR5 5UIW OX2 receptor 5WS3
TM1 40 1.33x33 CCR5 5UIW BLT1 receptor 5X33
TM1 41 1.34x34 CCR5 5UIW CXCR4 3ODU
TM1 42 1.35x35 CCR5 5UIW CCR5 5UIW
TM1 43 1.36x36 CCR5 5UIW CCR5 5UIW
TM1 44 1.37x37 CCR5 5UIW CCR5 5UIW
TM1 45 1.38x38 CCR5 5UIW CCR5 5UIW
TM1 46 1.39x39 CCR5 5UIW CCR5 5UIW
TM1 47 1.40x40 CCR5 5UIW CCR5 5UIW
TM1 48 1.41x41 CCR5 5UIW CCR5 5UIW
TM1 49 1.42x42 CCR5 5UIW CCR5 5UIW
TM1 50 1.43x43 CCR5 5UIW CCR5 5UIW
TM1 51 1.44x44 CCR5 5UIW AT1 receptor 4ZUD
TM1 52 1.45x45 CCR5 5UIW CCR5 5UIW
TM1 53 1.46x46 CCR5 5UIW CCR5 5UIW
TM1 54 1.47x47 CCR5 5UIW μ receptor 4DKL
TM1 55 1.48x48 CCR5 5UIW CCR9 5LWE
TM1 56 1.49x49 CCR5 5UIW CCR5 5UIW
TM1 57 1.50x50 CCR5 5UIW CCR5 5UIW
TM1 58 1.51x51 CCR5 5UIW CCR9 5LWE
TM1 59 1.52x52 CCR5 5UIW NTS1 receptor 4BUO
TM1 60 1.53x53 CCR5 5UIW CCR5 5UIW
TM1 61 1.54x54 CCR5 5UIW CCR2 5T1A
TM1 62 1.55x55 CCR5 5UIW CCR5 5UIW
TM1 63 1.56x56 CCR5 5UIW CXCR4 3ODU
TM1 64 1.57x57 CCR5 5UIW CCR5 5UIW
TM1 65 1.58x58 CCR5 5UIW apelin receptor 5VBL
TM1 66 1.59x59 CCR5 5UIW OX2 receptor 5WS3
TM1 67 1.60x60 CCR5 5UIW CCR5 5UIW
ICL1 68 12.48x48 - - - -
ICL1 69 12.49x49 AT1 receptor 4ZUD β2-adrenoceptor 5JQH
ICL1 70 12.50x50 AT1 receptor 4ZUD AT1 receptor 4ZUD
ICL1 71 12.51x51 - - - -
TM2 72 2.37x37 CCR5 5UIW CCR5 5UIW
TM2 73 2.38x38 CCR5 5UIW CCR5 5UIW
TM2 74 2.39x39 CCR5 5UIW CCR5 5UIW
TM2 75 2.40x40 CCR5 5UIW CCR5 5UIW
TM2 76 2.41x41 CCR5 5UIW AT1 receptor 4ZUD
TM2 77 2.42x42 CCR5 5UIW CCR5 5UIW
TM2 78 2.43x43 CCR5 5UIW CCR5 5UIW
TM2 79 2.44x44 CCR5 5UIW CCR5 5UIW
TM2 80 2.45x45 CCR5 5UIW CCR5 5UIW
TM2 81 2.46x46 CCR5 5UIW CCR5 5UIW
TM2 82 2.47x47 CCR5 5UIW CCR5 5UIW
TM2 83 2.48x48 CCR5 5UIW CCR5 5UIW
TM2 84 2.49x49 CCR5 5UIW CCR5 5UIW
TM2 85 2.50x50 CCR5 5UIW CCR5 5UIW
TM2 86 2.51x51 CCR5 5UIW CCR5 5UIW
TM2 87 2.52x52 CCR5 5UIW CCR2 5T1A
TM2 88 2.53x53 CCR5 5UIW CCR5 5UIW
TM2 89 2.54x54 CCR5 5UIW CXCR4 3ODU
TM2 90 2.55x55 CCR5 5UIW Rhodopsin 1GZM
TM2 91 2.56x56 CCR5 5UIW M1 receptor 5CXV
TM2 92 2.57x57 CCR5 5UIW CCR2 5T1A
TM2 93 2.58x58 CCR5 5UIW CCR5 5UIW
TM2 94 2.59x59 CCR5 5UIW CCR5 5UIW
TM2 95 2.60x60 CCR5 5UIW CCR5 5UIW
TM2 96 2.61x61 CCR5 5UIW NOP receptor 5DHG
TM2 97 2.62x62 CCR5 5UIW ETB receptor 5X93
TM2 98 2.63x63 CCR5 5UIW CCR5 5UIW
TM2 99 2.64x64 CCR5 5UIW CCR5 5UIW
TM2 100 2.65x65 CCR5 5UIW CCR5 5UIW
TM2 101 2.66x66 CCR5 5UIW US28 5WB1
ECL1 102 23.49x49 CCR5 5UIW CCR5 5UIW
ECL1 103 23.50x50 CCR5 5UIW CCR5 5UIW
ECL1 104 23.51x51 CCR5 5UIW CCR2 5T1A
ECL1 105 23.52x52 CCR5 5UIW CCR5 5UIW
TM3 106 3.21x21 CCR5 5UIW CCR5 5UIW
TM3 107 3.22x22 CCR5 5UIW BLT1 receptor 5X33
TM3 108 3.23x23 CCR5 5UIW - -
TM3 109 3.24x24 CCR5 5UIW CXCR4 3ODU
TM3 110 3.25x25 CCR5 5UIW CCR5 5UIW
TM3 111 3.26x26 CCR5 5UIW CCR2 5T1A
TM3 112 3.27x27 CCR5 5UIW A1 receptor 5UEN
TM3 113 3.28x28 CCR5 5UIW OX2 receptor 5WS3
TM3 114 3.29x29 CCR5 5UIW AT1 receptor 4ZUD
TM3 115 3.30x30 CCR5 5UIW - -
TM3 116 3.31x31 CCR5 5UIW CCR9 5LWE
TM3 117 3.32x32 CCR5 5UIW CCR5 5UIW
TM3 118 3.33x33 CCR5 5UIW C5a1 receptor 5O9H
TM3 119 3.34x34 CCR5 5UIW CXCR4 3ODU
TM3 120 3.35x35 CCR5 5UIW CCR5 5UIW
TM3 121 3.36x36 CCR5 5UIW CCR5 5UIW
TM3 122 3.37x37 CCR5 5UIW CXCR4 3ODU
TM3 123 3.38x38 CCR5 5UIW CCR5 5UIW
TM3 124 3.39x39 CCR5 5UIW CCR5 5UIW
TM3 125 3.40x40 CCR5 5UIW CCR5 5UIW
TM3 126 3.41x41 CCR5 5UIW CCR5 5UIW
TM3 127 3.42x42 CCR5 5UIW CCR5 5UIW
TM3 128 3.43x43 CCR5 5UIW H1 receptor 3RZE
TM3 129 3.44x44 CCR5 5UIW CCR9 5LWE
TM3 130 3.45x45 CCR5 5UIW CCR5 5UIW
TM3 131 3.46x46 CCR5 5UIW μ receptor 4DKL
TM3 132 3.47x47 CCR5 5UIW CXCR4 3ODU
TM3 133 3.48x48 CCR5 5UIW CCR5 5UIW
TM3 134 3.49x49 CCR5 5UIW CCR5 5UIW
TM3 135 3.50x50 CCR5 5UIW CCR5 5UIW
TM3 136 3.51x51 CCR5 5UIW CCR5 5UIW
TM3 137 3.52x52 CCR5 5UIW CCR5 5UIW
TM3 138 3.53x53 CCR5 5UIW CCR5 5UIW
TM3 139 3.54x54 CCR5 5UIW CCR2 5T1A
TM3 140 3.55x55 CCR5 5UIW CCR5 5UIW
TM3 141 3.56x56 CCR5 5UIW CCR5 5UIW
ICL2 142 34.50x50 CCR5 5UIW CCR5 5UIW
ICL2 143 34.51x51 CCR5 5UIW CCR5 4MBS
ICL2 144 34.52x52 CCR5 5UIW CCR5 5UIW
ICL2 145 34.53x53 CCR5 5UIW BLT1 receptor 5X33
ICL2 146 34.54x54 CCR5 5UIW CCR5 4MBS
ICL2 147 34.55x55 CCR5 5UIW C5a1 receptor 5O9H
ICL2 148 34.56x56 CCR5 5UIW CCR5 5UIW
ICL2 149 34.57x57 CCR5 5UIW CCR5 5UIW
TM4 150 4.38x38 CCR5 5UIW CCR5 5UIW
TM4 151 4.39x39 CCR5 5UIW CXCR4 3ODU
TM4 152 4.40x40 CCR5 5UIW CCR5 5UIW
TM4 153 4.41x41 CCR5 5UIW CCR9 5LWE
TM4 154 4.42x42 CCR5 5UIW CCR5 5UIW
TM4 155 4.43x43 CCR5 5UIW CCR5 5UIW
TM4 156 4.44x44 CCR5 5UIW μ receptor 4DKL
TM4 157 4.45x45 CCR5 5UIW CCR5 5UIW
TM4 158 4.46x46 CCR5 5UIW CCR5 5UIW
TM4 159 4.47x47 CCR5 5UIW OX1 receptor 4ZJ8
TM4 160 4.48x48 CCR5 5UIW NOP receptor 5DHG
TM4 161 4.49x49 CCR5 5UIW CCR5 5UIW
TM4 162 4.50x50 CCR5 5UIW CCR5 5UIW
TM4 163 4.51x51 CCR5 5UIW - -
TM4 164 4.52x52 CCR5 5UIW CCR5 5UIW
TM4 165 4.53x53 CCR5 5UIW CCR5 5UIW
TM4 166 4.54x54 CCR5 5UIW CCR5 5UIW
TM4 167 4.55x55 CCR5 5UIW CCR5 5UIW
TM4 168 4.56x56 CCR5 5UIW CCR5 5UIW
TM4 169 4.57x57 CCR5 5UIW CCR5 5UIW
TM4 170 4.58x59 CCR5 5UIW CCR5 5UIW
TM4 171 4.59x60 CCR5 5UIW CCR5 5UIW
TM4 172 4.60x61 CCR5 5UIW CCR2 5T1A
TM4 173 4.61x62 CCR5 5UIW CXCR4 3ODU
TM4 174 4.62x63 CCR5 5UIW κ receptor 4DJH
TM4 175 4.63x64 CCR5 5UIW CCR5 5UIW
TM4 176 4.64x65 CCR5 5UIW - -
ECL2 177 CCR5 5UIW - -
ECL2 178 CCR5 5UIW - -
ECL2 179 CCR5 5UIW - -
ECL2 180 CCR5 5UIW - -
ECL2 181 CCR5 5UIW CCR5 5UIW
ECL2 182 CCR5 5UIW - -
ECL2 183 CCR5 5UIW - -
ECL2 184 CCR5 5UIW - -
ECL2 185 CCR5 5UIW - -
ECL2 186 CCR5 5UIW - -
ECL2 187 45.50x50 CCR5 5UIW CCR5 5UIW
ECL2 188 45.51x51 CCR5 5UIW - -
ECL2 189 45.52x52 CCR5 5UIW US28 4XT1
ECL2 190 - - - -
ECL2 191 - - - -
ECL2 192 - - - -
ECL2 193 - - - -
TM5 194 5.30x31 CCR5 5UIW - -
TM5 195 5.31x32 CCR5 5UIW δ receptor 4N6H
TM5 196 5.32x33 CCR5 5UIW NTS1 receptor 4BUO
TM5 197 5.33x34 CCR5 5UIW - -
TM5 198 5.34x35 CCR5 5UIW CCR5 5UIW
TM5 199 5.35x36 CCR5 5UIW CCR5 5UIW
TM5 200 5.36x37 CCR5 5UIW CXCR4 3ODU
TM5 201 5.37x38 CCR5 5UIW μ receptor 4DKL
TM5 202 5.38x39 CCR5 5UIW - -
TM5 203 5.39x40 CCR5 5UIW P2Y1 receptor 4XNW
TM5 204 5.40x41 CCR5 5UIW CCR5 5UIW
TM5 205 5.41x42 CCR5 5UIW US28 4XT1
TM5 206 5.42x43 CCR5 5UIW CCR5 5UIW
TM5 207 5.43x44 CCR5 5UIW CCR2 5T1A
TM5 208 5.44x45 CCR5 5UIW CCR5 5UIW
TM5 209 5.45x46 CCR5 5UIW CCR5 5UIW
TM5 210 5.46x461 CCR5 5UIW CCR5 5UIW
TM5 211 5.47x47 CCR5 5UIW CCR5 5UIW
TM5 212 5.48x48 CCR5 5UIW CCR5 5UIW
TM5 213 5.49x49 CCR5 5UIW κ receptor 4DJH
TM5 214 5.50x50 CCR5 5UIW CCR5 5UIW
TM5 215 5.51x51 CCR5 5UIW CCR5 5UIW
TM5 216 5.52x52 CCR5 5UIW OX1 receptor 4ZJ8
TM5 217 5.53x53 CCR5 5UIW CCR2 5T1A
TM5 218 5.54x54 CCR5 5UIW CCR5 5UIW
TM5 219 5.55x55 CCR5 5UIW CXCR4 3ODU
TM5 220 5.56x56 CCR5 5UIW ETB receptor 5X93
TM5 221 5.57x57 CCR5 5UIW CCR5 5UIW
TM5 222 5.58x58 CCR5 5UIW CCR5 5UIW
TM5 223 5.59x59 CCR5 5UIW CCR5 5UIW
TM5 224 5.60x60 CCR5 5UIW LPA6 receptor 5XSZ
TM5 225 5.61x61 CCR5 5UIW CCR5 5UIW
TM5 226 5.62x62 CCR5 5UIW CXCR4 3ODU
TM5 227 5.63x63 CCR5 5UIW NOP receptor 5DHG
TM5 228 5.64x64 CCR5 5UIW CCR5 5UIW
TM5 229 5.65x65 CCR5 5UIW CCR5 5UIW
TM5 230 5.66x66 CCR5 5UIW D4 receptor 5WIV
TM5 231 5.67x67 CCR5 5UIW - -
TM5 232 5.68x68 US28 4XT1 - -
ICL3 233 - - - -
ICL3 234 - - - -
ICL3 235 - - - -
ICL3 236 - - - -
TM6 237 6.30x30 CCR5 5UIW CXCR4 3ODU
TM6 238 6.31x31 CCR5 5UIW - -
TM6 239 6.32x32 CCR5 5UIW CXCR4 3ODU
TM6 240 6.33x33 CCR5 5UIW CCR2 5T1A
TM6 241 6.34x34 CCR5 5UIW CCR5 5UIW
TM6 242 6.35x35 CCR5 5UIW CXCR4 3ODU
TM6 243 6.36x36 CCR5 5UIW μ receptor 4DKL
TM6 244 6.37x37 CCR5 5UIW CCR5 5UIW
TM6 245 6.38x38 CCR5 5UIW CCR5 5UIW
TM6 246 6.39x39 CCR5 5UIW AT1 receptor 4ZUD
TM6 247 6.40x40 CCR5 5UIW CCR9 5LWE
TM6 248 6.41x41 CCR5 5UIW AT1 receptor 4ZUD
TM6 249 6.42x42 CCR5 5UIW apelin receptor 5VBL
TM6 250 6.43x43 CCR5 5UIW A2A receptor 3VG9
TM6 251 6.44x44 CCR5 5UIW CXCR4 3ODU
TM6 252 6.45x45 CCR5 5UIW Rhodopsin 1GZM
TM6 253 6.46x46 CCR5 5UIW NOP receptor 5DHG
TM6 254 6.47x47 CCR5 5UIW CCR5 5UIW
TM6 255 6.48x48 CCR5 5UIW CCR5 5UIW
TM6 256 6.49x49 CCR5 5UIW CCR2 5T1A
TM6 257 6.50x50 CCR5 5UIW CCR5 5UIW
TM6 258 6.51x51 CCR5 5UIW CCR5 5UIW
TM6 259 6.52x52 CCR5 5UIW CCR5 5UIW
TM6 260 6.53x53 CCR5 5UIW CCR5 5UIW
TM6 261 6.54x54 CCR5 5UIW CCR5 5UIW
TM6 262 6.55x55 CCR5 5UIW CCR5 5UIW
TM6 263 6.56x56 CCR5 5UIW AT1 receptor 4ZUD
TM6 264 6.57x57 CCR5 5UIW CCR5 5UIW
TM6 265 6.58x58 CCR5 5UIW κ receptor 4DJH
TM6 266 6.59x59 CCR5 5UIW CCR5 5UIW
TM6 267 6.60x60 CCR5 5UIW AT1 receptor 4ZUD
TM6 268 6.61x61 CCR5 5UIW LPA6 receptor 5XSZ
TM6 269 6.62x62 CCR5 4MBS CCR2 5T1A
TM6 270 6.63x63 CCR5 4MBS CXCR4 3ODU
TM6 271 6.64x64 CCR5 4MBS CXCR4 3ODU
TM6 272 6.65x65 CCR5 4MBS - -
ECL3 273 - - - -
ECL3 274 - - - -
TM7 275 7.24x23 CCR5 5UIW AT1 receptor 4ZUD
TM7 276 7.25x24 CCR5 5UIW CCR5 5UIW
TM7 277 7.26x25 CCR5 5UIW P2Y12 receptor 4NTJ
TM7 278 7.27x26 CCR5 5UIW CXCR4 3ODU
TM7 279 7.28x27 CCR5 5UIW CXCR4 3ODU
TM7 280 7.29x28 CCR5 5UIW US28 4XT1
TM7 281 7.30x29 CCR5 5UIW - -
TM7 282 7.31x30 CCR5 5UIW CCR5 5UIW
TM7 283 7.32x31 CCR5 5UIW CCR5 5UIW
TM7 284 7.33x32 CCR5 5UIW NTS1 receptor 4BUO
TM7 285 7.34x33 CCR5 5UIW CCR5 5UIW
TM7 286 7.35x34 CCR5 5UIW CXCR4 3ODU
TM7 287 7.36x35 CCR5 5UIW CCR5 5UIW
TM7 288 7.37x36 CCR5 5UIW D4 receptor 5WIV
TM7 289 7.38x37 CCR5 5UIW CCR5 5UIW
TM7 290 7.39x38 CCR5 5UIW CCR5 5UIW
TM7 291 7.40x39 CCR5 5UIW CCR5 5UIW
TM7 292 7.41x40 CCR5 5UIW CCR5 5UIW
TM7 293 7.42x41 CCR5 5UIW CXCR4 3ODU
TM7 294 7.43x42 CCR5 5UIW CXCR4 3ODU
TM7 295 7.44x43 CCR5 5UIW NOP receptor 5DHG
TM7 296 7.45x45 CCR5 5UIW CCR5 5UIW
TM7 297 7.46x46 CCR5 5UIW CCR5 5UIW
TM7 298 7.47x47 CCR5 5UIW CCR5 5UIW
TM7 299 7.48x48 CCR5 5UIW CXCR4 3ODU
TM7 300 7.49x49 CCR5 5UIW CCR5 5UIW
TM7 301 7.50x50 CCR5 5UIW CCR5 5UIW
TM7 302 7.51x51 CCR5 5UIW CCR5 5UIW
TM7 303 7.52x52 CCR5 5UIW CCR5 5UIW
TM7 304 7.53x53 CCR5 5UIW CCR5 5UIW
TM7 305 7.54x54 CCR5 5UIW P2Y1 receptor 4XNW
TM7 306 7.55x55 CCR5 5UIW CCR5 5UIW
TM7 307 7.56x56 CCR5 5UIW μ receptor 4DKL
H8 308 8.47x47 CCR5 5UIW CCR5 5UIW
H8 309 8.48x48 CCR5 5UIW CCR5 4MBS
H8 310 8.49x49 CCR5 5UIW CCR2 5T1A
H8 311 8.50x50 CCR5 5UIW CCR5 5UIW
H8 312 8.51x51 CCR5 5UIW CCR5 5UIW
H8 313 8.52x52 CCR5 5UIW H1 receptor 3RZE
H8 314 8.53x53 CCR5 5UIW CCR5 5UIW
H8 315 8.54x54 CCR5 5UIW - -
H8 316 8.55x55 CCR5 5UIW CCR5 5UIW
H8 317 8.56x56 CCR5 5UIW LPA1 receptor 4Z36
H8 318 8.57x57 CCR5 5UIW δ receptor 4N6H
H8 319 8.58x58 CCR5 5UIW CCR5 5UIW
H8 320 8.59x59 CCR5 5UIW CCR9 5LWE
C-term 321 - - - -
C-term 322 - - - -
C-term 323 - - - -
C-term 324 - - - -
C-term 325 - - - -