CCR6 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): 0.96 docs)

VERSION

2018-07-10

MAIN TEMPLATE

CCR5 (sequence similarity: 57%) PDB: 5UIW

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 86.1 8.1 5.8
Side-chains 32.3 49.4 18.4

Number of backbone templates: 6
Number of rotamer templates: 38

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5UIW
4ZUD
5C1M
5VBL
4XT1
5LWE
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 36 CCR5 5UIW CCR5 5UIW
N-term 37 CCR5 5UIW CCR5 5UIW
N-term 38 CCR5 5UIW CCR5 5UIW
N-term 39 CCR5 5UIW CCR5 5UIW
N-term 40 CCR5 5UIW CCR5 5UIW
TM1 41 1.27x27 CCR5 5UIW CCR5 5UIW
TM1 42 1.28x28 CCR5 5UIW CCR9 5LWE
TM1 43 1.29x29 CCR5 5UIW CCR5 5UIW
TM1 44 1.30x30 CCR5 5UIW CCR9 5LWE
TM1 45 1.31x31 CCR5 5UIW NTS1 receptor 4BUO
TM1 46 1.32x32 CCR5 5UIW - -
TM1 47 1.33x33 CCR5 5UIW BLT1 receptor 5X33
TM1 48 1.34x34 CCR5 5UIW CCR9 5LWE
TM1 49 1.35x35 CCR5 5UIW NTS1 receptor 4BUO
TM1 50 1.36x36 CCR5 5UIW CCR5 5UIW
TM1 51 1.37x37 CCR5 5UIW BLT1 receptor 5X33
TM1 52 1.38x38 CCR5 5UIW OX1 receptor 4ZJ8
TM1 53 1.39x39 CCR5 5UIW CCR5 5UIW
TM1 54 1.40x40 CCR5 5UIW CCR5 5UIW
TM1 55 1.41x41 CCR5 5UIW CCR5 5UIW
TM1 56 1.42x42 CCR5 5UIW CXCR4 3ODU
TM1 57 1.43x43 CCR5 5UIW μ receptor 4DKL
TM1 58 1.44x44 CCR5 5UIW AT1 receptor 4ZUD
TM1 59 1.45x45 CCR5 5UIW CCR5 5UIW
TM1 60 1.46x46 CCR5 5UIW CCR5 5UIW
TM1 61 1.47x47 CCR5 5UIW BLT1 receptor 5X33
TM1 62 1.48x48 CCR5 5UIW CCR9 5LWE
TM1 63 1.49x49 CCR5 5UIW CCR5 5UIW
TM1 64 1.50x50 CCR5 5UIW CCR5 5UIW
TM1 65 1.51x51 CCR5 5UIW M3 receptor 4U15
TM1 66 1.52x52 CCR5 5UIW CCR5 5UIW
TM1 67 1.53x53 CCR5 5UIW CCR5 5UIW
TM1 68 1.54x54 CCR5 5UIW CCR2 5T1A
TM1 69 1.55x55 CCR5 5UIW AT1 receptor 4ZUD
TM1 70 1.56x56 CCR5 5UIW apelin receptor 5VBL
TM1 71 1.57x57 CCR5 5UIW M1 receptor 5CXV
TM1 72 1.58x58 CCR5 5UIW C5a1 receptor 5O9H
TM1 73 1.59x59 CCR5 5UIW AT1 receptor 4ZUD
TM1 74 1.60x60 CCR5 5UIW CCR5 5UIW
ICL1 75 12.48x48 - - - -
ICL1 76 12.49x49 AT1 receptor 4ZUD AT1 receptor 4YAY
ICL1 77 12.50x50 AT1 receptor 4ZUD - -
ICL1 78 12.51x51 - - - -
TM2 79 2.37x37 CCR5 5UIW CCR5 5UIW
TM2 80 2.38x38 CCR5 5UIW CCR5 5UIW
TM2 81 2.39x39 CCR5 5UIW CCR5 5UIW
TM2 82 2.40x40 CCR5 5UIW CCR5 5UIW
TM2 83 2.41x41 CCR5 5UIW AT1 receptor 4ZUD
TM2 84 2.42x42 CCR5 5UIW CCR5 5UIW
TM2 85 2.43x43 CCR5 5UIW CCR5 5UIW
TM2 86 2.44x44 CCR5 5UIW CCR5 5UIW
TM2 87 2.45x45 CCR5 5UIW CCR5 5UIW
TM2 88 2.46x46 CCR5 5UIW - -
TM2 89 2.47x47 CCR5 5UIW CCR5 5UIW
TM2 90 2.48x48 CCR5 5UIW CCR5 5UIW
TM2 91 2.49x49 CCR5 5UIW CCR9 5LWE
TM2 92 2.50x50 CCR5 5UIW CCR5 5UIW
TM2 93 2.51x51 CCR5 5UIW A2A receptor 3VG9
TM2 94 2.52x52 CCR5 5UIW CCR9 5LWE
TM2 95 2.53x53 CCR5 5UIW CCR5 5UIW
TM2 96 2.54x54 CCR5 5UIW CXCR4 3ODU
TM2 97 2.55x55 CCR5 5UIW CCR5 5UIW
TM2 98 2.56x56 CCR5 5UIW CCR5 5UIW
TM2 99 2.57x57 CCR5 5UIW CCR9 5LWE
TM2 100 2.58x58 CCR5 5UIW CCR5 5UIW
TM2 101 2.59x59 CCR5 5UIW CCR5 5UIW
TM2 102 2.60x60 CCR5 5UIW CCR5 5UIW
TM2 103 2.61x61 CCR5 5UIW CCR5 5UIW
TM2 104 2.62x62 CCR5 5UIW CXCR4 3ODU
TM2 105 2.63x63 CCR5 5UIW CCR2 5T1A
TM2 106 2.64x64 CCR5 5UIW PAR2 5NDD
TM2 107 2.65x65 CCR5 5UIW CCR5 5UIW
TM2 108 2.66x66 CCR5 5UIW OX2 receptor 5WS3
ECL1 109 - - - -
ECL1 110 23.49x49 CCR5 5UIW D4 receptor 5WIV
ECL1 111 23.50x50 CCR5 5UIW CCR5 5UIW
ECL1 112 23.51x51 CCR5 5UIW CCR2 5T1A
ECL1 113 23.52x52 CCR5 5UIW CCR5 5UIW
TM3 114 3.21x21 CCR5 5UIW D4 receptor 5WIV
TM3 115 3.22x22 CCR5 5UIW CCR5 5UIW
TM3 116 3.23x23 CCR5 5UIW CCR2 5T1A
TM3 117 3.24x24 CCR5 5UIW LPA1 receptor 4Z35
TM3 118 3.25x25 CCR5 5UIW CCR5 5UIW
TM3 119 3.26x26 CCR5 5UIW CCR9 5LWE
TM3 120 3.27x27 CCR5 5UIW CCR5 5UIW
TM3 121 3.28x28 CCR5 5UIW CCR5 5UIW
TM3 122 3.29x29 CCR5 5UIW - -
TM3 123 3.30x30 CCR5 5UIW CCR5 5UIW
TM3 124 3.31x31 CCR5 5UIW CXCR4 3ODU
TM3 125 3.32x32 CCR5 5UIW CCR5 5UIW
TM3 126 3.33x33 CCR5 5UIW OX1 receptor 4ZJ8
TM3 127 3.34x34 CCR5 5UIW CCR5 5UIW
TM3 128 3.35x35 CCR5 5UIW CCR9 5LWE
TM3 129 3.36x36 CCR5 5UIW CCR5 5UIW
TM3 130 3.37x37 CCR5 5UIW M3 receptor 4U15
TM3 131 3.38x38 CCR5 5UIW PAF receptor 5ZKP
TM3 132 3.39x39 CCR5 5UIW CCR5 5UIW
TM3 133 3.40x40 CCR5 5UIW - -
TM3 134 3.41x41 CCR5 5UIW CCR9 5LWE
TM3 135 3.42x42 CCR5 5UIW CCR9 5LWE
TM3 136 3.43x43 CCR5 5UIW CXCR4 3ODU
TM3 137 3.44x44 CCR5 5UIW AT1 receptor 4ZUD
TM3 138 3.45x45 CCR5 5UIW CCR9 5LWE
TM3 139 3.46x46 CCR5 5UIW CCR9 5LWE
TM3 140 3.47x47 CCR5 5UIW CXCR4 3ODU
TM3 141 3.48x48 CCR5 5UIW - -
TM3 142 3.49x49 CCR5 5UIW CCR5 5UIW
TM3 143 3.50x50 CCR5 5UIW CCR5 5UIW
TM3 144 3.51x51 CCR5 5UIW CCR5 5UIW
TM3 145 3.52x52 CCR5 5UIW CCR9 5LWE
TM3 146 3.53x53 CCR5 5UIW CCR5 5UIW
TM3 147 3.54x54 CCR5 5UIW CCR9 5LWE
TM3 148 3.55x55 CCR5 5UIW CCR5 5UIW
TM3 149 3.56x56 CCR5 5UIW CCR9 5LWE
ICL2 150 34.50x50 CCR5 5UIW CCR5 5UIW
ICL2 151 34.51x51 CCR5 5UIW - -
ICL2 152 34.52x52 CCR5 5UIW μ receptor 4DKL
ICL2 153 34.53x53 CCR5 5UIW BLT1 receptor 5X33
ICL2 154 34.54x54 CCR5 5UIW Rhodopsin 4ZWJ
ICL2 155 34.55x55 CCR5 5UIW C5a1 receptor 5O9H
ICL2 156 34.56x56 CCR5 5UIW A2A receptor 3VG9
ICL2 157 34.57x57 CCR5 5UIW CCR5 5UIW
ICL2 158 34.58x58 - - - -
ICL2 159 - - - -
TM4 160 4.38x38 CCR5 5UIW CCR5 5UIW
TM4 161 4.39x39 CCR5 5UIW CCR9 5LWE
TM4 162 4.40x40 CCR5 5UIW CB1 receptor 5TGZ
TM4 163 4.41x41 CCR5 5UIW OX2 receptor 5WS3
TM4 164 4.42x42 CCR5 5UIW CCR9 5LWE
TM4 165 4.43x43 CCR5 5UIW CCR9 5LWE
TM4 166 4.44x44 CCR5 5UIW μ receptor 4DKL
TM4 167 4.45x45 CCR5 5UIW κ receptor 4DJH
TM4 168 4.46x46 CCR5 5UIW CCR9 5LWE
TM4 169 4.47x47 CCR5 5UIW OX1 receptor 4ZJ8
TM4 170 4.48x48 CCR5 5UIW C5a1 receptor 5O9H
TM4 171 4.49x49 CCR5 5UIW CXCR4 3ODU
TM4 172 4.50x50 CCR5 5UIW CCR5 5UIW
TM4 173 4.51x51 CCR5 5UIW BLT1 receptor 5X33
TM4 174 4.52x52 CCR5 5UIW CCR9 5LWE
TM4 175 4.53x53 CCR5 5UIW BLT1 receptor 5X33
TM4 176 4.54x54 CCR5 5UIW CCR5 5UIW
TM4 177 4.55x55 CCR5 5UIW OX2 receptor 5WS3
TM4 178 4.56x56 CCR5 5UIW μ receptor 4DKL
TM4 179 4.57x57 μ receptor 5C1M μ receptor 5C1M
TM4 180 4.58x58 μ receptor 5C1M P2Y1 receptor 4XNW
TM4 181 4.59x59 μ receptor 5C1M κ receptor 4DJH
TM4 182 4.60x60 CCR5 5UIW LPA6 receptor 5XSZ
TM4 183 4.61x61 CCR5 5UIW Y1 receptor 5ZBH
TM4 184 4.62x62 CCR5 5UIW κ receptor 4DJH
TM4 185 4.63x63 CCR5 5UIW M1 receptor 5CXV
TM4 186 4.64x64 CCR5 5UIW - -
ECL2 187 CCR5 5UIW - -
ECL2 188 CCR5 5UIW - -
ECL2 189 CCR5 5UIW - -
ECL2 190 CCR5 5UIW - -
ECL2 191 CCR5 5UIW - -
ECL2 192 CCR5 5UIW - -
ECL2 193 CCR5 5UIW - -
ECL2 194 CCR5 5UIW - -
ECL2 195 CCR5 5UIW - -
ECL2 196 CCR5 5UIW - -
ECL2 197 45.50x50 CCR5 5UIW CCR5 5UIW
ECL2 198 45.51x51 CCR5 5UIW H1 receptor 3RZE
ECL2 199 45.52x52 CCR5 5UIW CCR2 5T1A
ECL2 200 - - - -
ECL2 201 apelin receptor 5VBL apelin receptor 5VBL
ECL2 202 apelin receptor 5VBL - -
ECL2 203 apelin receptor 5VBL - -
ECL2 204 apelin receptor 5VBL apelin receptor 5VBL
ECL2 205 apelin receptor 5VBL - -
ECL2 206 apelin receptor 5VBL - -
ECL2 207 apelin receptor 5VBL - -
ECL2 208 - - - -
TM5 209 5.33x34 CCR5 5UIW BLT1 receptor 5X33
TM5 210 5.34x35 CCR5 5UIW CCR5 5UIW
TM5 211 5.35x36 CCR5 5UIW CCR5 5UIW
TM5 212 5.36x37 CCR5 5UIW κ receptor 4DJH
TM5 213 5.37x38 CCR5 5UIW μ receptor 4DKL
TM5 214 5.38x39 CCR5 5UIW κ receptor 4DJH
TM5 215 5.39x40 CCR5 5UIW BLT1 receptor 5X33
TM5 216 5.40x41 CCR5 5UIW - -
TM5 217 5.41x42 CCR5 5UIW Y1 receptor 5ZBH
TM5 218 5.42x43 CCR5 5UIW BLT1 receptor 5X33
TM5 219 5.43x44 CCR5 5UIW C5a1 receptor 5O9H
TM5 220 5.44x45 CCR5 5UIW NOP receptor 5DHG
TM5 221 5.45x46 CCR5 5UIW μ receptor 4DKL
TM5 222 5.46x461 CCR5 5UIW CCR5 5UIW
TM5 223 5.47x47 CCR5 5UIW AT1 receptor 4YAY
TM5 224 5.48x48 CCR5 5UIW 5-HT2C receptor 6BQH
TM5 225 5.49x49 CCR5 5UIW κ receptor 4DJH
TM5 226 5.50x50 CCR5 5UIW CCR5 5UIW
TM5 227 5.51x51 CCR5 5UIW CCR5 5UIW
TM5 228 5.52x52 CCR5 5UIW - -
TM5 229 5.53x53 CCR5 5UIW Y1 receptor 5ZBH
TM5 230 5.54x54 CCR5 5UIW CCR5 5UIW
TM5 231 5.55x55 CCR5 5UIW κ receptor 4DJH
TM5 232 5.56x56 CCR5 5UIW β2-adrenoceptor 5JQH
TM5 233 5.57x57 CCR5 5UIW CCR5 5UIW
TM5 234 5.58x58 CCR5 5UIW CCR5 5UIW
TM5 235 5.59x59 CCR5 5UIW AT1 receptor 4ZUD
TM5 236 5.60x60 CCR5 5UIW C5a1 receptor 5O9H
TM5 237 5.61x61 CCR5 5UIW CCR5 5UIW
TM5 238 5.62x62 CCR5 5UIW Rhodopsin 1GZM
TM5 239 5.63x63 CCR5 5UIW CCR5 5UIW
TM5 240 5.64x64 CCR5 5UIW CCR5 5UIW
TM5 241 5.65x65 CCR5 5UIW CCR5 5UIW
TM5 242 5.66x66 CCR5 5UIW - -
TM5 243 5.67x67 CCR5 5UIW - -
TM5 244 5.68x68 US28 4XT1 C5a1 receptor 5O9H
ICL3 245 - - - -
ICL3 246 - - - -
ICL3 247 - - - -
ICL3 248 - - - -
TM6 249 6.30x30 CCR5 5UIW CCR5 5UIW
TM6 250 6.31x31 CCR5 5UIW CCR9 5LWE
TM6 251 6.32x32 CCR5 5UIW CCR9 5LWE
TM6 252 6.33x33 CCR5 5UIW CCR9 5LWE
TM6 253 6.34x34 CCR5 5UIW - -
TM6 254 6.35x35 CCR5 5UIW CCR5 5UIW
TM6 255 6.36x36 CCR5 5UIW CCR2 5T1A
TM6 256 6.37x37 CCR5 5UIW CCR5 5UIW
TM6 257 6.38x38 CCR5 5UIW CCR9 5LWE
TM6 258 6.39x39 CCR5 5UIW AT1 receptor 4ZUD
TM6 259 6.40x40 CCR5 5UIW CCR9 5LWE
TM6 260 6.41x41 CCR5 5UIW AT1 receptor 4ZUD
TM6 261 6.42x42 CCR5 5UIW CXCR4 3ODU
TM6 262 6.43x43 CCR5 5UIW CCR5 5UIW
TM6 263 6.44x44 CCR5 5UIW CCR9 5LWE
TM6 264 6.45x45 CCR5 5UIW 5-HT2C receptor 6BQH
TM6 265 6.46x46 CCR5 5UIW CXCR4 3ODU
TM6 266 6.47x47 CCR5 5UIW CXCR4 3ODU
TM6 267 6.48x48 CCR5 5UIW CCR9 5LWE
TM6 268 6.49x49 CCR5 5UIW AT1 receptor 4ZUD
TM6 269 6.50x50 CCR5 5UIW CCR5 5UIW
TM6 270 6.51x51 CCR5 5UIW AT1 receptor 4ZUD
TM6 271 6.52x52 CCR5 5UIW CCR5 5UIW
TM6 272 6.53x53 CCR5 5UIW - -
TM6 273 6.54x54 CCR5 5UIW CCR5 5UIW
TM6 274 6.55x55 CCR5 5UIW CCR5 5UIW
TM6 275 6.56x56 CCR5 5UIW CCR5 5UIW
TM6 276 6.57x57 CCR5 5UIW CCR9 5LWE
TM6 277 6.58x58 CCR5 5UIW A2A receptor 3VG9
TM6 278 6.59x59 CCR5 5UIW μ receptor 4DKL
TM6 279 6.60x60 CCR5 5UIW - -
TM6 280 6.61x61 CCR5 5UIW Y1 receptor 5ZBH
TM6 281 6.62x62 CCR9 5LWE CXCR4 3ODU
TM6 282 6.63x63 CCR9 5LWE - -
TM6 283 6.64x64 CCR9 5LWE US28 4XT1
TM6 284 6.65x65 CCR9 5LWE CCR9 5LWE
ECL3 285 - - - -
ECL3 286 - - - -
TM7 287 7.24x23 CCR5 5UIW US28 5WB1
TM7 288 7.25x24 CCR5 5UIW CCR5 5UIW
TM7 289 7.26x25 CCR5 5UIW - -
TM7 290 7.27x26 CCR5 5UIW CCR5 5UIW
TM7 291 7.28x27 CCR5 5UIW CXCR4 3ODU
TM7 292 7.29x28 CCR5 5UIW 5-HT2C receptor 6BQH
TM7 293 7.30x29 CCR5 5UIW C5a1 receptor 5O9H
TM7 294 7.31x30 CCR5 5UIW CCR9 5LWE
TM7 295 7.32x31 CCR5 5UIW FFA1 receptor 5TZY
TM7 296 7.33x32 CCR5 5UIW NTS1 receptor 4BUO
TM7 297 7.34x33 CCR5 5UIW P2Y1 receptor 4XNW
TM7 298 7.35x34 CCR5 5UIW P2Y12 receptor 4NTJ
TM7 299 7.36x35 CCR5 5UIW OX2 receptor 5WS3
TM7 300 7.37x36 CCR5 5UIW CCR5 5UIW
TM7 301 7.38x37 CCR5 5UIW CCR5 5UIW
TM7 302 7.39x38 CCR5 5UIW CCR5 5UIW
TM7 303 7.40x39 CCR5 5UIW A2A receptor 3VG9
TM7 304 7.41x40 CCR5 5UIW CCR5 5UIW
TM7 305 7.42x41 CCR5 5UIW CCR9 5LWE
TM7 306 7.43x42 CCR5 5UIW CCR9 5LWE
TM7 307 7.44x43 CCR5 5UIW BLT1 receptor 5X33
TM7 308 7.45x45 CCR5 5UIW CCR5 5UIW
TM7 309 7.46x46 CCR5 5UIW CCR5 5UIW
TM7 310 7.47x47 CCR5 5UIW CCR5 5UIW
TM7 311 7.48x48 CCR5 5UIW CCR9 5LWE
TM7 312 7.49x49 CCR5 5UIW CCR5 5UIW
TM7 313 7.50x50 CCR5 5UIW CCR5 5UIW
TM7 314 7.51x51 CCR5 5UIW CCR9 5LWE
TM7 315 7.52x52 CCR5 5UIW CCR9 5LWE
TM7 316 7.53x53 CCR5 5UIW CCR5 5UIW
TM7 317 7.54x54 CCR5 5UIW CCR5 5UIW
TM7 318 7.55x55 CCR5 5UIW CCR5 5UIW
TM7 319 7.56x56 CCR5 5UIW - -
H8 320 8.47x47 CCR5 5UIW CCR5 5UIW
H8 321 8.48x48 CCR5 5UIW A1 receptor 5UEN
H8 322 8.49x49 CCR5 5UIW CCR2 5T1A
H8 323 8.50x50 CCR5 5UIW CCR5 5UIW
H8 324 8.51x51 CCR5 5UIW CCR5 5UIW
H8 325 8.52x52 CCR5 5UIW CCR5 5UIW
H8 326 8.53x53 CCR5 5UIW CCR5 5UIW
H8 327 8.54x54 CCR5 5UIW μ receptor 4DKL
H8 328 8.55x55 CCR5 5UIW CCR5 5UIW
H8 329 8.56x56 CCR5 5UIW CCR9 5LWE
H8 330 8.57x57 CCR5 5UIW D2 receptor 6CM4
H8 331 8.58x58 CCR5 5UIW CCR9 5LWE
H8 332 8.59x59 CCR5 5UIW CCR9 5LWE
H8 333 8.60x60 CCR9 5LWE A1 receptor 5UEN
H8 334 8.61x61 CCR9 5LWE CCR9 5LWE
H8 335 8.62x62 CCR9 5LWE - -
H8 336 8.63x63 CCR9 5LWE - -
H8 337 8.64x64 CCR9 5LWE - -
H8 338 8.65x65 CCR9 5LWE - -
H8 339 8.66x66 CCR9 5LWE - -
H8 340 8.67x67 CCR9 5LWE - -
C-term 341 - - - -
C-term 342 - - - -
C-term 343 - - - -
C-term 344 - - - -
C-term 345 - - - -