CCR7 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): 0.97 docs)

VERSION

2018-07-10

MAIN TEMPLATE

CCR5 (sequence similarity: 60%) PDB: 5UIW

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 86.0 8.4 5.5
Side-chains 34.1 46.4 19.5

Number of backbone templates: 5
Number of rotamer templates: 35

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5UIW
4ZUD
5VBL
4XT1
5LWE
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 48 CCR5 5UIW CCR5 5UIW
N-term 49 CCR5 5UIW CCR5 5UIW
N-term 50 CCR5 5UIW CCR5 5UIW
N-term 51 CCR5 5UIW CCR5 5UIW
N-term 52 CCR5 5UIW CCR5 5UIW
TM1 53 1.27x27 CCR5 5UIW CCR5 5UIW
TM1 54 1.28x28 CCR5 5UIW CCR9 5LWE
TM1 55 1.29x29 CCR5 5UIW CXCR4 3ODU
TM1 56 1.30x30 CCR5 5UIW CCR9 5LWE
TM1 57 1.31x31 CCR5 5UIW - -
TM1 58 1.32x32 CCR5 5UIW CCR5 5UIW
TM1 59 1.33x33 CCR5 5UIW OX2 receptor 5WS3
TM1 60 1.34x34 CCR5 5UIW CCR9 5LWE
TM1 61 1.35x35 CCR5 5UIW CCR5 5UIW
TM1 62 1.36x36 CCR5 5UIW CCR5 5UIW
TM1 63 1.37x37 CCR5 5UIW BLT1 receptor 5X33
TM1 64 1.38x38 CCR5 5UIW - -
TM1 65 1.39x39 CCR5 5UIW CCR5 5UIW
TM1 66 1.40x40 CCR5 5UIW CCR5 5UIW
TM1 67 1.41x41 CCR5 5UIW CXCR4 3ODU
TM1 68 1.42x42 CCR5 5UIW CXCR4 3ODU
TM1 69 1.43x43 CCR5 5UIW μ receptor 4DKL
TM1 70 1.44x44 CCR5 5UIW P2Y12 receptor 4NTJ
TM1 71 1.45x45 CCR5 5UIW CCR9 5LWE
TM1 72 1.46x46 CCR5 5UIW CCR5 5UIW
TM1 73 1.47x47 CCR5 5UIW μ receptor 4DKL
TM1 74 1.48x48 CCR5 5UIW CCR9 5LWE
TM1 75 1.49x49 CCR5 5UIW CCR5 5UIW
TM1 76 1.50x50 CCR5 5UIW CCR5 5UIW
TM1 77 1.51x51 CCR5 5UIW CXCR4 3ODU
TM1 78 1.52x52 CCR5 5UIW CCR5 5UIW
TM1 79 1.53x53 CCR5 5UIW CCR5 5UIW
TM1 80 1.54x54 CCR5 5UIW CCR2 5T1A
TM1 81 1.55x55 CCR5 5UIW CCR5 5UIW
TM1 82 1.56x56 CCR5 5UIW apelin receptor 5VBL
TM1 83 1.57x57 CCR5 5UIW CCR9 5LWE
TM1 84 1.58x58 CCR5 5UIW CCR5 5UIW
TM1 85 1.59x59 CCR5 5UIW CCR9 5LWE
TM1 86 1.60x60 CCR5 5UIW - -
ICL1 87 12.48x48 - - - -
ICL1 88 12.49x49 AT1 receptor 4ZUD β2-adrenoceptor 5JQH
ICL1 89 12.50x50 AT1 receptor 4ZUD AT1 receptor 4ZUD
ICL1 90 12.51x51 - - - -
TM2 91 2.37x37 CCR5 5UIW CCR9 5LWE
TM2 92 2.38x38 CCR5 5UIW CCR5 5UIW
TM2 93 2.39x39 CCR5 5UIW CCR5 5UIW
TM2 94 2.40x40 CCR5 5UIW CCR5 5UIW
TM2 95 2.41x41 CCR5 5UIW LPA6 receptor 5XSZ
TM2 96 2.42x42 CCR5 5UIW CCR5 5UIW
TM2 97 2.43x43 CCR5 5UIW CCR5 5UIW
TM2 98 2.44x44 CCR5 5UIW CCR5 5UIW
TM2 99 2.45x45 CCR5 5UIW CCR5 5UIW
TM2 100 2.46x46 CCR5 5UIW CCR5 5UIW
TM2 101 2.47x47 CCR5 5UIW CCR5 5UIW
TM2 102 2.48x48 CCR5 5UIW CXCR4 3ODU
TM2 103 2.49x49 CCR5 5UIW CCR9 5LWE
TM2 104 2.50x50 CCR5 5UIW CCR5 5UIW
TM2 105 2.51x51 CCR5 5UIW A2A receptor 3VG9
TM2 106 2.52x52 CCR5 5UIW CCR9 5LWE
TM2 107 2.53x53 CCR5 5UIW CCR5 5UIW
TM2 108 2.54x54 CCR5 5UIW CCR5 5UIW
TM2 109 2.55x55 CCR5 5UIW CCR5 5UIW
TM2 110 2.56x56 CCR5 5UIW CCR5 5UIW
TM2 111 2.57x57 CCR5 5UIW CCR9 5LWE
TM2 112 2.58x58 CCR5 5UIW CCR5 5UIW
TM2 113 2.59x59 CCR5 5UIW CCR5 5UIW
TM2 114 2.60x60 CCR5 5UIW CCR5 5UIW
TM2 115 2.61x61 CCR5 5UIW CCR5 5UIW
TM2 116 2.62x62 CCR5 5UIW ETB receptor 5X93
TM2 117 2.63x63 CCR5 5UIW CCR2 5T1A
TM2 118 2.64x64 CCR5 5UIW CCR5 5UIW
TM2 119 2.65x65 CCR5 5UIW CCR5 5UIW
TM2 120 2.66x66 CCR5 5UIW M4 receptor 5DSG
ECL1 121 23.49x49 CCR5 5UIW κ receptor 4DJH
ECL1 122 23.50x50 CCR5 5UIW CCR5 5UIW
ECL1 123 23.51x51 CCR5 5UIW CCR2 5T1A
ECL1 124 23.52x52 CCR5 5UIW CCR5 5UIW
TM3 125 3.21x21 CCR5 5UIW CCR5 5UIW
TM3 126 3.22x22 CCR5 5UIW LPA1 receptor 4Z35
TM3 127 3.23x23 CCR5 5UIW A2A receptor 3VG9
TM3 128 3.24x24 CCR5 5UIW apelin receptor 5VBL
TM3 129 3.25x25 CCR5 5UIW CCR5 5UIW
TM3 130 3.26x26 CCR5 5UIW CCR9 5LWE
TM3 131 3.27x27 CCR5 5UIW CCR5 5UIW
TM3 132 3.28x28 CCR5 5UIW OX2 receptor 5WS3
TM3 133 3.29x29 CCR5 5UIW - -
TM3 134 3.30x30 CCR5 5UIW AT1 receptor 4ZUD
TM3 135 3.31x31 CCR5 5UIW CXCR4 3ODU
TM3 136 3.32x32 CCR5 5UIW CCR5 5UIW
TM3 137 3.33x33 CCR5 5UIW CCR9 5LWE
TM3 138 3.34x34 CCR5 5UIW CCR9 5LWE
TM3 139 3.35x35 CCR5 5UIW BLT1 receptor 5X33
TM3 140 3.36x36 CCR5 5UIW CCR5 5UIW
TM3 141 3.37x37 CCR5 5UIW CCR5 5UIW
TM3 142 3.38x38 CCR5 5UIW CCR5 5UIW
TM3 143 3.39x39 CCR5 5UIW CCR5 5UIW
TM3 144 3.40x40 CCR5 5UIW - -
TM3 145 3.41x41 CCR5 5UIW CCR9 5LWE
TM3 146 3.42x42 CCR5 5UIW CCR9 5LWE
TM3 147 3.43x43 CCR5 5UIW CXCR4 3ODU
TM3 148 3.44x44 CCR5 5UIW M3 receptor 4U15
TM3 149 3.45x45 CCR5 5UIW CCR9 5LWE
TM3 150 3.46x46 CCR5 5UIW CCR9 5LWE
TM3 151 3.47x47 CCR5 5UIW CXCR4 3ODU
TM3 152 3.48x48 CCR5 5UIW CCR5 5UIW
TM3 153 3.49x49 CCR5 5UIW CCR5 5UIW
TM3 154 3.50x50 CCR5 5UIW CCR5 5UIW
TM3 155 3.51x51 CCR5 5UIW CCR5 5UIW
TM3 156 3.52x52 CCR5 5UIW NOP receptor 5DHG
TM3 157 3.53x53 CCR5 5UIW CCR5 5UIW
TM3 158 3.54x54 CCR5 5UIW CCR9 5LWE
TM3 159 3.55x55 CCR5 5UIW CCR5 5UIW
TM3 160 3.56x56 CCR5 5UIW CCR9 5LWE
ICL2 161 34.50x50 CCR5 5UIW CCR5 5UIW
ICL2 162 34.51x51 CCR5 5UIW CCR2 5T1A
ICL2 163 34.52x52 CCR5 5UIW M1 receptor 5CXV
ICL2 164 34.53x53 CCR5 5UIW CCR5 5UIW
ICL2 165 34.54x54 CCR5 5UIW CCR9 5LWE
ICL2 166 34.55x55 CCR5 5UIW C5a1 receptor 5O9H
ICL2 167 34.56x56 CCR5 5UIW - -
ICL2 168 34.57x57 CCR5 5UIW CCR5 5UIW
ICL2 169 34.58x58 - - - -
ICL2 170 - - - -
TM4 171 4.38x38 CCR5 5UIW - -
TM4 172 4.39x39 CCR5 5UIW CCR9 5LWE
TM4 173 4.40x40 CCR5 5UIW CCR9 5LWE
TM4 174 4.41x41 CCR5 5UIW PAR2 5NDD
TM4 175 4.42x42 CCR5 5UIW CCR9 5LWE
TM4 176 4.43x43 CCR5 5UIW CCR9 5LWE
TM4 177 4.44x44 CCR5 5UIW δ receptor 4N6H
TM4 178 4.45x45 CCR5 5UIW OX2 receptor 5WS3
TM4 179 4.46x46 CCR5 5UIW CCR9 5LWE
TM4 180 4.47x47 CCR5 5UIW CCR5 5UIW
TM4 181 4.48x48 CCR5 5UIW CXCR4 3ODU
TM4 182 4.49x49 CCR5 5UIW CCR9 5LWE
TM4 183 4.50x50 CCR5 5UIW CCR5 5UIW
TM4 184 4.51x51 CCR5 5UIW CXCR4 3ODU
TM4 185 4.52x52 CCR5 5UIW CCR9 5LWE
TM4 186 4.53x53 CCR5 5UIW CCR5 5UIW
TM4 187 4.54x54 CCR5 5UIW - -
TM4 188 4.55x55 CCR5 5UIW NOP receptor 5DHG
TM4 189 4.56x56 CCR5 5UIW CCR9 5LWE
TM4 190 4.57x57 CCR5 5UIW CCR5 5UIW
TM4 191 4.58x59 CCR5 5UIW CCR9 5LWE
TM4 192 4.59x60 CCR5 5UIW CCR5 5UIW
TM4 193 4.60x61 CCR5 5UIW CCR9 5LWE
TM4 194 4.61x62 CCR5 5UIW BLT1 receptor 5X33
TM4 195 4.62x63 CCR5 5UIW C5a1 receptor 5O9H
TM4 196 4.63x64 CCR5 5UIW C5a1 receptor 5O9H
TM4 197 4.64x65 CCR5 5UIW - -
ECL2 198 - - - -
ECL2 199 apelin receptor 5VBL - -
ECL2 200 apelin receptor 5VBL - -
ECL2 201 apelin receptor 5VBL - -
ECL2 202 apelin receptor 5VBL - -
ECL2 203 apelin receptor 5VBL - -
ECL2 204 apelin receptor 5VBL - -
ECL2 205 apelin receptor 5VBL - -
ECL2 206 apelin receptor 5VBL - -
ECL2 207 apelin receptor 5VBL - -
ECL2 208 apelin receptor 5VBL - -
ECL2 209 - - - -
ECL2 210 45.50x50 CCR5 5UIW CCR5 5UIW
ECL2 211 45.51x51 CCR5 5UIW CCR5 5UIW
ECL2 212 45.52x52 CCR5 5UIW μ receptor 4DKL
ECL2 213 CCR5 5UIW - -
ECL2 214 CCR5 5UIW - -
ECL2 215 CCR5 5UIW - -
ECL2 216 CCR5 5UIW - -
ECL2 217 CCR5 5UIW - -
TM5 218 5.33x34 CCR5 5UIW - -
TM5 219 5.34x35 CCR5 5UIW - -
TM5 220 5.35x36 CCR5 5UIW 5-HT2B receptor 4IB4
TM5 221 5.36x37 CCR5 5UIW AT1 receptor 4ZUD
TM5 222 5.37x38 CCR5 5UIW M3 receptor 4U15
TM5 223 5.38x39 CCR5 5UIW M3 receptor 4U15
TM5 224 5.39x40 CCR5 5UIW CXCR4 3ODU
TM5 225 5.40x41 CCR5 5UIW apelin receptor 5VBL
TM5 226 5.41x42 CCR5 5UIW β2-adrenoceptor 5JQH
TM5 227 5.42x43 CCR5 5UIW - -
TM5 228 5.43x44 CCR5 5UIW US28 4XT1
TM5 229 5.44x45 CCR5 5UIW C5a1 receptor 5O9H
TM5 230 5.45x46 CCR5 5UIW H1 receptor 3RZE
TM5 231 5.46x461 CCR5 5UIW CCR5 5UIW
TM5 232 5.47x47 CCR5 5UIW AT1 receptor 4YAY
TM5 233 5.48x48 CCR5 5UIW AT1 receptor 4ZUD
TM5 234 5.49x49 CCR5 5UIW apelin receptor 5VBL
TM5 235 5.50x50 CCR5 5UIW CCR5 5UIW
TM5 236 5.51x51 CCR5 5UIW CCR5 5UIW
TM5 237 5.52x52 CCR5 5UIW CCR5 5UIW
TM5 238 5.53x53 CCR5 5UIW - -
TM5 239 5.54x54 CCR5 5UIW CCR5 5UIW
TM5 240 5.55x55 CCR5 5UIW NOP receptor 5DHG
TM5 241 5.56x56 CCR5 5UIW ETB receptor 5X93
TM5 242 5.57x57 CCR5 5UIW CCR5 5UIW
TM5 243 5.58x58 CCR5 5UIW CCR5 5UIW
TM5 244 5.59x59 CCR5 5UIW OX2 receptor 5WS3
TM5 245 5.60x60 CCR5 5UIW NTS1 receptor 4BUO
TM5 246 5.61x61 CCR5 5UIW CCR5 5UIW
TM5 247 5.62x62 CCR5 5UIW CXCR4 3ODU
TM5 248 5.63x63 CCR5 5UIW BLT1 receptor 5X33
TM5 249 5.64x64 CCR5 5UIW CCR5 5UIW
TM5 250 5.65x65 CCR5 5UIW CCR5 5UIW
TM5 251 5.66x66 CCR5 5UIW CCR5 5UIW
TM5 252 5.67x67 CCR5 5UIW - -
TM5 253 5.68x68 US28 4XT1 C5a1 receptor 5O9H
ICL3 254 - - - -
ICL3 255 - - - -
ICL3 256 - - - -
ICL3 257 - - - -
TM6 258 6.30x30 CCR5 5UIW CCR5 5UIW
TM6 259 6.31x31 CCR5 5UIW - -
TM6 260 6.32x32 CCR5 5UIW CCR9 5LWE
TM6 261 6.33x33 CCR5 5UIW CCR9 5LWE
TM6 262 6.34x34 CCR5 5UIW - -
TM6 263 6.35x35 CCR5 5UIW CCR9 5LWE
TM6 264 6.36x36 CCR5 5UIW CCR2 5T1A
TM6 265 6.37x37 CCR5 5UIW CCR5 5UIW
TM6 266 6.38x38 CCR5 5UIW CCR9 5LWE
TM6 267 6.39x39 CCR5 5UIW AT1 receptor 4ZUD
TM6 268 6.40x40 CCR5 5UIW CCR9 5LWE
TM6 269 6.41x41 CCR5 5UIW AT1 receptor 4ZUD
TM6 270 6.42x42 CCR5 5UIW apelin receptor 5VBL
TM6 271 6.43x43 CCR5 5UIW CCR5 5UIW
TM6 272 6.44x44 CCR5 5UIW CCR9 5LWE
TM6 273 6.45x45 CCR5 5UIW μ receptor 4DKL
TM6 274 6.46x46 CCR5 5UIW μ receptor 4DKL
TM6 275 6.47x47 CCR5 5UIW CCR5 5UIW
TM6 276 6.48x48 CCR5 5UIW CCR9 5LWE
TM6 277 6.49x49 CCR5 5UIW CXCR4 3ODU
TM6 278 6.50x50 CCR5 5UIW CCR5 5UIW
TM6 279 6.51x51 CCR5 5UIW CCR5 5UIW
TM6 280 6.52x52 CCR5 5UIW CCR5 5UIW
TM6 281 6.53x53 CCR5 5UIW Rhodopsin 1GZM
TM6 282 6.54x54 CCR5 5UIW CCR5 5UIW
TM6 283 6.55x55 CCR5 5UIW μ receptor 4DKL
TM6 284 6.56x56 CCR5 5UIW CCR5 5UIW
TM6 285 6.57x57 CCR5 5UIW NOP receptor 5DHG
TM6 286 6.58x58 CCR5 5UIW CCR9 5LWE
TM6 287 6.59x59 CCR5 5UIW CCR5 5UIW
TM6 288 6.60x60 CCR5 5UIW OX2 receptor 5WS3
TM6 289 6.61x61 CCR5 5UIW AT2 receptor 5UNG
TM6 290 6.62x62 CCR9 5LWE - -
TM6 291 6.63x63 CCR9 5LWE - -
TM6 292 6.64x64 CCR9 5LWE - -
TM6 293 6.65x65 CCR9 5LWE - -
ECL3 294 - - - -
ECL3 295 CCR9 5LWE - -
ECL3 296 - - - -
TM7 297 7.24x23 CCR5 5UIW NTS1 receptor 4BUO
TM7 298 7.25x24 CCR5 5UIW CCR5 5UIW
TM7 299 7.26x25 CCR5 5UIW CXCR4 3ODU
TM7 300 7.27x26 CCR5 5UIW ETB receptor 5X93
TM7 301 7.28x27 CCR5 5UIW CCR5 5UIW
TM7 302 7.29x28 CCR5 5UIW 5-HT2C receptor 6BQH
TM7 303 7.30x29 CCR5 5UIW CCR2 5T1A
TM7 304 7.31x30 CCR5 5UIW CCR5 5UIW
TM7 305 7.32x31 CCR5 5UIW M2 receptor 3UON
TM7 306 7.33x32 CCR5 5UIW CCR9 5LWE
TM7 307 7.34x33 CCR5 5UIW CCR5 5UIW
TM7 308 7.35x34 CCR5 5UIW κ receptor 4DJH
TM7 309 7.36x35 CCR5 5UIW 5-HT1B receptor 4IAQ
TM7 310 7.37x36 CCR5 5UIW CCR5 5UIW
TM7 311 7.38x37 CCR5 5UIW CCR5 5UIW
TM7 312 7.39x38 CCR5 5UIW M3 receptor 4U15
TM7 313 7.40x39 CCR5 5UIW C5a1 receptor 5O9H
TM7 314 7.41x40 CCR5 5UIW CCR5 5UIW
TM7 315 7.42x41 CCR5 5UIW CCR9 5LWE
TM7 316 7.43x42 CCR5 5UIW - -
TM7 317 7.44x43 CCR5 5UIW apelin receptor 5VBL
TM7 318 7.45x45 CCR5 5UIW - -
TM7 319 7.46x46 CCR5 5UIW CCR5 5UIW
TM7 320 7.47x47 CCR5 5UIW CCR5 5UIW
TM7 321 7.48x48 CCR5 5UIW M3 receptor 4U15
TM7 322 7.49x49 CCR5 5UIW CCR5 5UIW
TM7 323 7.50x50 CCR5 5UIW CCR5 5UIW
TM7 324 7.51x51 CCR5 5UIW apelin receptor 5VBL
TM7 325 7.52x52 CCR5 5UIW CCR9 5LWE
TM7 326 7.53x53 CCR5 5UIW CCR5 5UIW
TM7 327 7.54x54 CCR5 5UIW CCR5 5UIW
TM7 328 7.55x55 CCR5 5UIW CCR5 5UIW
TM7 329 7.56x56 CCR5 5UIW - -
H8 330 8.47x47 CCR5 5UIW CCR5 5UIW
H8 331 8.48x48 CCR5 5UIW - -
H8 332 8.49x49 CCR5 5UIW CCR2 5T1A
H8 333 8.50x50 CCR5 5UIW CCR5 5UIW
H8 334 8.51x51 CCR5 5UIW CCR5 5UIW
H8 335 8.52x52 CCR5 5UIW CCR5 5UIW
H8 336 8.53x53 CCR5 5UIW CCR9 5LWE
H8 337 8.54x54 CCR5 5UIW CCR5 5UIW
H8 338 8.55x55 CCR5 5UIW - -
H8 339 8.56x56 CCR5 5UIW CCR9 5LWE
H8 340 8.57x57 CCR5 5UIW δ receptor 4N6H
H8 341 8.58x58 CCR5 5UIW CCR5 5UIW
H8 342 8.59x59 CCR5 5UIW CCR9 5LWE
H8 343 8.60x60 CCR9 5LWE A1 receptor 5UEN
H8 344 8.61x61 CCR9 5LWE CCR9 5LWE
H8 345 8.62x62 CCR9 5LWE CCR9 5LWE
H8 346 8.63x63 CCR9 5LWE - -
H8 347 8.64x64 CCR9 5LWE - -
H8 348 8.65x65 CCR9 5LWE CCR9 5LWE
H8 349 8.66x66 CCR9 5LWE CCR9 5LWE
H8 350 8.67x67 CCR9 5LWE A2A receptor 2YDV
C-term 351 - - - -
C-term 352 - - - -
C-term 353 - - - -
C-term 354 - - - -
C-term 355 - - - -