CX3CR1 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): 1.04 docs)

VERSION

2018-07-10

MAIN TEMPLATE

CCR5 (sequence similarity: 60%) PDB: 5UIW

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 86.7 3.8 9.6
Side-chains 39.2 43.0 17.7

Number of backbone templates: 5
Number of rotamer templates: 36

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5UIW
4ZUD
5UNF
4XT1
5T1A
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 21 CCR5 5UIW CCR5 5UIW
N-term 22 CCR5 5UIW CCR5 5UIW
N-term 23 CCR5 5UIW CCR5 5UIW
N-term 24 CCR5 5UIW CCR5 5UIW
N-term 25 CCR5 5UIW CCR5 5UIW
TM1 26 1.27x27 CCR5 5UIW ETB receptor 5X93
TM1 27 1.28x28 CCR5 5UIW - -
TM1 28 1.29x29 CCR5 5UIW - -
TM1 29 1.30x30 CCR5 5UIW CXCR4 3ODU
TM1 30 1.31x31 CCR5 5UIW CCR2 5T1A
TM1 31 1.32x32 CCR5 5UIW PAR1 3VW7
TM1 32 1.33x33 CCR5 5UIW AT1 receptor 4ZUD
TM1 33 1.34x34 CCR5 5UIW CXCR4 3ODU
TM1 34 1.35x35 CCR5 5UIW CCR5 5UIW
TM1 35 1.36x36 CCR5 5UIW S1P1 receptor 3V2Y
TM1 36 1.37x37 CCR5 5UIW BLT1 receptor 5X33
TM1 37 1.38x38 CCR5 5UIW - -
TM1 38 1.39x39 CCR5 5UIW CCR5 5UIW
TM1 39 1.40x40 CCR5 5UIW CCR5 5UIW
TM1 40 1.41x41 CCR5 5UIW κ receptor 4DJH
TM1 41 1.42x42 CCR5 5UIW CXCR4 3ODU
TM1 42 1.43x43 CCR5 5UIW CCR5 5UIW
TM1 43 1.44x44 CCR5 5UIW δ receptor 4N6H
TM1 44 1.45x45 CCR5 5UIW AT2 receptor 5UNG
TM1 45 1.46x46 CCR5 5UIW CCR5 5UIW
TM1 46 1.47x47 CCR5 5UIW δ receptor 4N6H
TM1 47 1.48x48 CCR5 5UIW CCR5 5UIW
TM1 48 1.49x49 CCR5 5UIW CCR5 5UIW
TM1 49 1.50x50 CCR5 5UIW CCR5 5UIW
TM1 50 1.51x51 CCR5 5UIW M1 receptor 5CXV
TM1 51 1.52x52 CCR5 5UIW CCR5 5UIW
TM1 52 1.53x53 CCR5 5UIW CCR5 5UIW
TM1 53 1.54x54 CCR5 5UIW CCR2 5T1A
TM1 54 1.55x55 CCR5 5UIW δ receptor 4N6H
TM1 55 1.56x56 CCR5 5UIW OX1 receptor 4ZJ8
TM1 56 1.57x57 CCR5 5UIW CCR5 5UIW
TM1 57 1.58x58 CCR5 5UIW US28 4XT1
TM1 58 1.59x59 CCR5 5UIW CCR2 5T1A
TM1 59 1.60x60 CCR5 5UIW CB1 receptor 5XRA
ICL1 60 12.48x48 - - - -
ICL1 61 12.49x49 AT1 receptor 4ZUD AT1 receptor 4YAY
ICL1 62 12.50x50 AT1 receptor 4ZUD - -
ICL1 63 12.51x51 - - - -
TM2 64 2.37x37 CCR5 5UIW CCR5 5UIW
TM2 65 2.38x38 CCR5 5UIW AT1 receptor 4ZUD
TM2 66 2.39x39 CCR5 5UIW CCR5 5UIW
TM2 67 2.40x40 CCR5 5UIW CCR5 5UIW
TM2 68 2.41x41 CCR5 5UIW CCR5 5UIW
TM2 69 2.42x42 CCR5 5UIW CCR5 5UIW
TM2 70 2.43x43 CCR5 5UIW CCR5 5UIW
TM2 71 2.44x44 CCR5 5UIW CCR5 5UIW
TM2 72 2.45x45 CCR5 5UIW CCR5 5UIW
TM2 73 2.46x46 CCR5 5UIW CCR5 5UIW
TM2 74 2.47x47 CCR5 5UIW CCR5 5UIW
TM2 75 2.48x48 CCR5 5UIW AT1 receptor 4ZUD
TM2 76 2.49x49 CCR5 5UIW CCR5 5UIW
TM2 77 2.50x50 CCR5 5UIW CCR5 5UIW
TM2 78 2.51x51 CCR5 5UIW CCR5 5UIW
TM2 79 2.52x52 CCR5 5UIW CCR2 5T1A
TM2 80 2.53x53 CCR5 5UIW CCR5 5UIW
TM2 81 2.54x54 CCR5 5UIW CXCR4 3ODU
TM2 82 2.55x55 CCR5 5UIW OX1 receptor 4ZJ8
TM2 83 2.56x56 CCR5 5UIW CCR5 5UIW
TM2 84 2.57x57 CCR5 5UIW CCR2 5T1A
TM2 85 2.58x58 CCR5 5UIW CCR5 5UIW
TM2 86 2.59x59 CCR5 5UIW CCR5 5UIW
TM2 87 2.60x60 CCR5 5UIW CCR5 5UIW
TM2 88 2.61x61 CCR5 5UIW M3 receptor 4U15
TM2 89 2.62x62 CCR5 5UIW CCR5 5UIW
TM2 90 2.63x63 CCR5 5UIW CCR5 5UIW
TM2 91 2.64x64 CCR5 5UIW BLT1 receptor 5X33
TM2 92 2.65x65 CCR5 5UIW OX1 receptor 4ZJ8
TM2 93 2.66x66 CCR5 5UIW CCR2 5T1A
ECL1 94 - - - -
ECL1 95 - - - -
ECL1 96 - - - -
ECL1 97 - - - -
ECL1 98 - - - -
ECL1 99 - - - -
ECL1 100 - - - -
TM3 101 3.24x24 CCR5 5UIW CCR5 5UIW
TM3 102 3.25x25 CCR5 5UIW CCR5 5UIW
TM3 103 3.26x26 CCR5 5UIW CCR2 5T1A
TM3 104 3.27x27 CCR5 5UIW β2-adrenoceptor 5JQH
TM3 105 3.28x28 CCR5 5UIW P2Y12 receptor 4NTJ
TM3 106 3.29x29 CCR5 5UIW CCR5 5UIW
TM3 107 3.30x30 CCR5 5UIW AT1 receptor 4ZUD
TM3 108 3.31x31 CCR5 5UIW Rhodopsin 1GZM
TM3 109 3.32x32 CCR5 5UIW US28 4XT1
TM3 110 3.33x33 CCR5 5UIW CCR5 5UIW
TM3 111 3.34x34 CCR5 5UIW CCR5 5UIW
TM3 112 3.35x35 CCR5 5UIW CCR5 5UIW
TM3 113 3.36x36 CCR5 5UIW CCR5 5UIW
TM3 114 3.37x37 CCR5 5UIW CCR5 5UIW
TM3 115 3.38x38 CCR5 5UIW CCR2 5T1A
TM3 116 3.39x39 CCR5 5UIW CXCR4 3ODU
TM3 117 3.40x40 CCR5 5UIW CCR5 5UIW
TM3 118 3.41x41 CCR5 5UIW CCR5 5UIW
TM3 119 3.42x42 CCR5 5UIW CCR5 5UIW
TM3 120 3.43x43 CCR5 5UIW CCR5 5UIW
TM3 121 3.44x44 CCR5 5UIW AT1 receptor 4ZUD
TM3 122 3.45x45 CCR5 5UIW M3 receptor 4U15
TM3 123 3.46x46 CCR5 5UIW CXCR4 3ODU
TM3 124 3.47x47 CCR5 5UIW CXCR4 3ODU
TM3 125 3.48x48 CCR5 5UIW CCR5 5UIW
TM3 126 3.49x49 CCR5 5UIW CCR5 5UIW
TM3 127 3.50x50 CCR5 5UIW CCR5 5UIW
TM3 128 3.51x51 CCR5 5UIW CCR5 5UIW
TM3 129 3.52x52 CCR5 5UIW CCR5 5UIW
TM3 130 3.53x53 CCR5 5UIW CCR5 5UIW
TM3 131 3.54x54 CCR5 5UIW CCR2 5T1A
TM3 132 3.55x55 CCR5 5UIW CCR5 5UIW
TM3 133 3.56x56 CCR5 5UIW - -
ICL2 134 34.50x50 CCR5 5UIW CCR5 5UIW
ICL2 135 34.51x51 CCR5 5UIW C5a1 receptor 5O9H
ICL2 136 34.52x52 CCR5 5UIW - -
ICL2 137 34.53x53 CCR5 5UIW BLT1 receptor 5X33
ICL2 138 34.54x54 CCR5 5UIW - -
ICL2 139 34.55x55 CCR5 5UIW C5a1 receptor 6C1R
ICL2 140 34.56x56 CCR5 5UIW - -
ICL2 141 34.57x57 CCR5 5UIW CCR5 5UIW
TM4 142 4.38x38 CCR5 5UIW CCR5 5UIW
TM4 143 4.39x39 CCR5 5UIW CCR5 5UIW
TM4 144 4.40x40 CCR5 5UIW - -
TM4 145 4.41x41 CCR5 5UIW Rhodopsin 1GZM
TM4 146 4.42x42 CCR5 5UIW CCR5 5UIW
TM4 147 4.43x43 CCR5 5UIW CCR5 5UIW
TM4 148 4.44x44 CCR5 5UIW - -
TM4 149 4.45x45 CCR5 5UIW δ receptor 4N6H
TM4 150 4.46x46 CCR5 5UIW CCR5 5UIW
TM4 151 4.47x47 CCR5 5UIW OX1 receptor 4ZJ8
TM4 152 4.48x48 CCR5 5UIW CXCR4 3ODU
TM4 153 4.49x49 CCR5 5UIW CXCR4 3ODU
TM4 154 4.50x50 CCR5 5UIW CCR5 5UIW
TM4 155 4.51x51 CCR5 5UIW NOP receptor 5DHG
TM4 156 4.52x52 CCR5 5UIW BLT1 receptor 5X33
TM4 157 4.53x53 CCR5 5UIW CCR5 5UIW
TM4 158 4.54x54 CCR5 5UIW 5-HT2C receptor 6BQH
TM4 159 4.55x55 CCR5 5UIW CXCR4 3ODU
TM4 160 4.56x56 CCR5 5UIW δ receptor 4N6H
TM4 161 4.57x57 CCR5 5UIW apelin receptor 5VBL
TM4 162 4.58x59 CCR5 5UIW D4 receptor 5WIV
TM4 163 4.59x60 CCR5 5UIW CCR5 5UIW
TM4 164 4.60x61 CCR5 5UIW OX1 receptor 4ZJ8
TM4 165 4.61x62 CCR5 5UIW CXCR4 3ODU
TM4 166 4.62x63 CCR5 5UIW δ receptor 4N6H
TM4 167 4.63x64 CCR5 5UIW CCR5 5UIW
TM4 168 4.64x65 CCR5 5UIW CCR5 5UIW
ECL2 169 - - - -
ECL2 170 - - - -
ECL2 171 - - - -
ECL2 172 - - - -
ECL2 173 - - - -
ECL2 174 - - - -
ECL2 175 45.50x50 CCR5 5UIW CCR5 5UIW
ECL2 176 45.51x51 CCR5 5UIW BLT1 receptor 5X33
ECL2 177 45.52x52 CCR5 5UIW - -
ECL2 178 - - - -
ECL2 179 AT2 receptor 5UNF - -
ECL2 180 AT2 receptor 5UNF AT2 receptor 5UNF
ECL2 181 AT2 receptor 5UNF - -
ECL2 182 AT2 receptor 5UNF - -
ECL2 183 - - - -
TM5 184 5.31x32 CCR5 5UIW NOP receptor 5DHG
TM5 185 5.32x33 CCR5 5UIW - -
TM5 186 5.33x34 CCR5 5UIW OX2 receptor 5WS3
TM5 187 5.34x35 CCR5 5UIW CCR5 5UIW
TM5 188 5.35x36 CCR5 5UIW AT1 receptor 4ZUD
TM5 189 5.36x37 CCR5 5UIW CXCR4 3ODU
TM5 190 5.37x38 CCR5 5UIW μ receptor 4DKL
TM5 191 5.38x39 CCR5 5UIW - -
TM5 192 5.39x40 CCR5 5UIW US28 4XT1
TM5 193 5.40x41 CCR5 5UIW apelin receptor 5VBL
TM5 194 5.41x42 CCR5 5UIW US28 4XT1
TM5 195 5.42x43 CCR5 5UIW M3 receptor 4U15
TM5 196 5.43x44 CCR5 5UIW CCR2 5T1A
TM5 197 5.44x45 CCR5 5UIW BLT1 receptor 5X33
TM5 198 5.45x46 CCR5 5UIW CCR5 5UIW
TM5 199 5.46x461 CCR5 5UIW CCR5 5UIW
TM5 200 5.47x47 CCR5 5UIW AT1 receptor 4YAY
TM5 201 5.48x48 CCR5 5UIW AT1 receptor 4ZUD
TM5 202 5.49x49 CCR5 5UIW CCR5 5UIW
TM5 203 5.50x50 CCR5 5UIW CCR5 5UIW
TM5 204 5.51x51 CCR5 5UIW CCR5 5UIW
TM5 205 5.52x52 CCR5 5UIW CCR5 5UIW
TM5 206 5.53x53 CCR5 5UIW CCR2 5T1A
TM5 207 5.54x54 CCR5 5UIW CCR5 5UIW
TM5 208 5.55x55 CCR5 5UIW NOP receptor 5DHG
TM5 209 5.56x56 CCR5 5UIW CB1 receptor 5TGZ
TM5 210 5.57x57 CCR5 5UIW CCR5 5UIW
TM5 211 5.58x58 CCR5 5UIW CCR5 5UIW
TM5 212 5.59x59 CCR5 5UIW apelin receptor 5VBL
TM5 213 5.60x60 CCR5 5UIW M3 receptor 4U15
TM5 214 5.61x61 CCR5 5UIW CCR5 5UIW
TM5 215 5.62x62 CCR5 5UIW CXCR4 3ODU
TM5 216 5.63x63 CCR5 5UIW apelin receptor 5VBL
TM5 217 5.64x64 CCR5 5UIW CCR5 5UIW
TM5 218 5.65x65 CCR5 5UIW CCR5 5UIW
TM5 219 5.66x66 CCR5 5UIW - -
TM5 220 5.67x67 CCR5 5UIW PAR1 3VW7
TM5 221 5.68x68 US28 4XT1 - -
ICL3 222 - - - -
ICL3 223 - - - -
ICL3 224 - - - -
ICL3 225 - - - -
TM6 226 6.30x30 CCR5 5UIW CXCR4 3ODU
TM6 227 6.31x31 CCR5 5UIW - -
TM6 228 6.32x32 CCR5 5UIW CXCR4 3ODU
TM6 229 6.33x33 CCR5 5UIW CCR2 5T1A
TM6 230 6.34x34 CCR5 5UIW - -
TM6 231 6.35x35 CCR5 5UIW CXCR4 3ODU
TM6 232 6.36x36 CCR5 5UIW CCR5 5UIW
TM6 233 6.37x37 CCR5 5UIW CCR5 5UIW
TM6 234 6.38x38 CCR5 5UIW δ receptor 4N6H
TM6 235 6.39x39 CCR5 5UIW CB1 receptor 5TGZ
TM6 236 6.40x40 CCR5 5UIW CCR9 5LWE
TM6 237 6.41x41 CCR5 5UIW AT1 receptor 4ZUD
TM6 238 6.42x42 CCR5 5UIW CCR5 5UIW
TM6 239 6.43x43 CCR5 5UIW CCR5 5UIW
TM6 240 6.44x44 CCR5 5UIW CXCR4 3ODU
TM6 241 6.45x45 CCR5 5UIW CCR5 5UIW
TM6 242 6.46x46 CCR5 5UIW CCR5 5UIW
TM6 243 6.47x47 CCR5 5UIW CCR5 5UIW
TM6 244 6.48x48 CCR5 5UIW CCR5 5UIW
TM6 245 6.49x49 CCR5 5UIW CCR2 5T1A
TM6 246 6.50x50 CCR5 5UIW CCR5 5UIW
TM6 247 6.51x51 CCR5 5UIW CCR5 5UIW
TM6 248 6.52x52 CCR5 5UIW CCR5 5UIW
TM6 249 6.53x53 CCR5 5UIW BLT1 receptor 5X33
TM6 250 6.54x54 CCR5 5UIW M3 receptor 4U15
TM6 251 6.55x55 CCR5 5UIW CCR2 5T1A
TM6 252 6.56x56 CCR5 5UIW AT1 receptor 4ZUD
TM6 253 6.57x57 CCR5 5UIW CCR5 5UIW
TM6 254 6.58x58 CCR5 5UIW κ receptor 4DJH
TM6 255 6.59x59 CCR5 5UIW CCR5 5UIW
TM6 256 6.60x60 CCR5 5UIW AT1 receptor 4ZUD
TM6 257 6.61x61 CCR5 5UIW US28 4XT1
TM6 258 6.62x62 CCR2 5T1A CXCR4 3ODU
TM6 259 6.63x63 CCR2 5T1A CCR9 5LWE
TM6 260 6.64x64 CCR2 5T1A P2Y1 receptor 4XNW
ECL3 261 - - - -
ECL3 262 AT1 receptor 4ZUD - -
ECL3 263 - - - -
TM7 264 7.24x23 CCR5 5UIW US28 5WB1
TM7 265 7.25x24 CCR5 5UIW CCR5 5UIW
TM7 266 7.26x25 CCR5 5UIW apelin receptor 5VBL
TM7 267 7.27x26 CCR5 5UIW - -
TM7 268 7.28x27 CCR5 5UIW OX1 receptor 4ZJ8
TM7 269 7.29x28 CCR5 5UIW 5-HT2C receptor 6BQH
TM7 270 7.30x29 CCR5 5UIW S1P1 receptor 3V2Y
TM7 271 7.31x30 CCR5 5UIW CCR5 5UIW
TM7 272 7.32x31 CCR5 5UIW BLT1 receptor 5X33
TM7 273 7.33x32 CCR5 5UIW Y1 receptor 5ZBH
TM7 274 7.34x33 CCR5 5UIW CCR5 5UIW
TM7 275 7.35x34 CCR5 5UIW δ receptor 4N6H
TM7 276 7.36x35 CCR5 5UIW CXCR4 3ODU
TM7 277 7.37x36 CCR5 5UIW CCR5 5UIW
TM7 278 7.38x37 CCR5 5UIW CCR5 5UIW
TM7 279 7.39x38 CCR5 5UIW CCR5 5UIW
TM7 280 7.40x39 CCR5 5UIW CCR5 5UIW
TM7 281 7.41x40 CCR5 5UIW PAR1 3VW7
TM7 282 7.42x41 CCR5 5UIW CXCR4 3ODU
TM7 283 7.43x42 CCR5 5UIW CXCR4 3ODU
TM7 284 7.44x43 CCR5 5UIW LPA6 receptor 5XSZ
TM7 285 7.45x45 CCR5 5UIW CCR5 5UIW
TM7 286 7.46x46 CCR5 5UIW CCR5 5UIW
TM7 287 7.47x47 CCR5 5UIW CCR5 5UIW
TM7 288 7.48x48 CCR5 5UIW CXCR4 3ODU
TM7 289 7.49x49 CCR5 5UIW CCR5 5UIW
TM7 290 7.50x50 CCR5 5UIW CCR5 5UIW
TM7 291 7.51x51 CCR5 5UIW AT1 receptor 4ZUD
TM7 292 7.52x52 CCR5 5UIW CCR5 5UIW
TM7 293 7.53x53 CCR5 5UIW CCR5 5UIW
TM7 294 7.54x54 CCR5 5UIW CCR5 5UIW
TM7 295 7.55x55 CCR5 5UIW CCR5 5UIW
TM7 296 7.56x56 CCR5 5UIW C5a1 receptor 5O9H
H8 297 8.47x47 CCR5 5UIW CCR5 5UIW
H8 298 8.48x48 CCR5 5UIW CCR2 5T1A
H8 299 8.49x49 CCR5 5UIW CCR2 5T1A
H8 300 8.50x50 CCR5 5UIW CCR5 5UIW
H8 301 8.51x51 CCR5 5UIW CCR5 5UIW
H8 302 8.52x52 CCR5 5UIW CCR2 5T1A
H8 303 8.53x53 CCR5 5UIW CCR5 5UIW
H8 304 8.54x54 CCR5 5UIW CCR5 5UIW
H8 305 8.55x55 CCR5 5UIW - -
H8 306 8.56x56 CCR5 5UIW M4 receptor 5DSG
H8 307 8.57x57 CCR5 5UIW δ receptor 4N6H
H8 308 8.58x58 CCR5 5UIW - -
C-term 309 - - - -
C-term 310 - - - -
C-term 311 - - - -
C-term 312 - - - -
C-term 313 - - - -