CX3CR1 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 7.21 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 47%) PDB: 6DDE

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 71.7 18.1 10.2
Side-chains 19.8 61.4 18.8

Number of backbone templates: 5
Number of rotamer templates: 37

NGL is a WebGL based 3D viewer powered by MMTF.

5UIW
6DDE
4ZUD
5UNF
5T1A
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 21 CCR5 5UIW CCR5 5UIW
N-term 22 CCR5 5UIW CCR5 5UIW
N-term 23 CCR5 5UIW CCR5 5UIW
N-term 24 CCR5 5UIW CCR5 5UIW
N-term 25 CCR5 5UIW CCR5 5UIW
TM1 26 1.27x27 CCR5 5UIW ETB receptor 5X93
TM1 27 1.28x28 CCR5 5UIW - -
TM1 28 1.29x29 CCR5 5UIW - -
TM1 29 1.30x30 CCR5 5UIW P2Y1 receptor 4XNW
TM1 30 1.31x31 μ receptor 6DDE A2A receptor 5WF5
TM1 31 1.32x32 μ receptor 6DDE PAR1 3VW7
TM1 32 1.33x33 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 33 1.34x34 μ receptor 6DDE PAR1 3VW7
TM1 34 1.35x35 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 35 1.36x36 μ receptor 6DDE LPA6 receptor 5XSZ
TM1 36 1.37x37 μ receptor 6DDE PAF receptor 5ZKQ
TM1 37 1.38x38 μ receptor 6DDE - -
TM1 38 1.39x39 μ receptor 6DDE μ receptor 6DDE
TM1 39 1.40x40 μ receptor 6DDE μ receptor 6DDE
TM1 40 1.41x41 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 41 1.42x42 μ receptor 6DDE PAF receptor 5ZKQ
TM1 42 1.43x43 μ receptor 6DDE PAR1 3VW7
TM1 43 1.44x44 μ receptor 6DDE FFA1 receptor 5TZY
TM1 44 1.45x45 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 45 1.46x46 μ receptor 6DDE μ receptor 6DDE
TM1 46 1.47x47 μ receptor 6DDE PAR1 3VW7
TM1 47 1.48x48 μ receptor 6DDE NTS1 receptor 4XES
TM1 48 1.49x49 μ receptor 6DDE μ receptor 6DDE
TM1 49 1.50x50 μ receptor 6DDE μ receptor 6DDE
TM1 50 1.51x51 μ receptor 6DDE M1 receptor 5CXV
TM1 51 1.52x52 μ receptor 6DDE μ receptor 6DDE
TM1 52 1.53x53 μ receptor 6DDE μ receptor 6DDE
TM1 53 1.54x54 μ receptor 6DDE CCR2 5T1A
TM1 54 1.55x55 μ receptor 6DDE NTS1 receptor 4XES
TM1 55 1.56x56 μ receptor 6DDE 5-HT2B receptor 4IB4
TM1 56 1.57x57 μ receptor 6DDE NTS1 receptor 4XES
TM1 57 1.58x58 μ receptor 6DDE FFA1 receptor 5TZY
TM1 58 1.59x59 μ receptor 6DDE CCR2 5T1A
TM1 59 1.60x60 μ receptor 6DDE apelin receptor 5VBL
ICL1 60 12.48x48 - - - -
ICL1 61 12.49x49 AT1 receptor 4ZUD 5-HT1B receptor 4IAQ
ICL1 62 12.50x50 AT1 receptor 4ZUD - -
ICL1 63 12.51x51 - - - -
TM2 64 2.37x37 CCR5 5UIW CCR5 5UIW
TM2 65 2.38x38 μ receptor 6DDE A2A receptor 4UHR
TM2 66 2.39x39 μ receptor 6DDE μ receptor 6DDE
TM2 67 2.40x40 μ receptor 6DDE CCR5 5UIW
TM2 68 2.41x41 μ receptor 6DDE μ receptor 6DDE
TM2 69 2.42x42 μ receptor 6DDE μ receptor 6DDE
TM2 70 2.43x43 μ receptor 6DDE P2Y12 receptor 4NTJ
TM2 71 2.44x44 μ receptor 6DDE PAR1 3VW7
TM2 72 2.45x45 μ receptor 6DDE μ receptor 6DDE
TM2 73 2.46x46 μ receptor 6DDE μ receptor 6DDE
TM2 74 2.47x47 μ receptor 6DDE μ receptor 6DDE
TM2 75 2.48x48 μ receptor 6DDE μ receptor 6DDE
TM2 76 2.49x49 μ receptor 6DDE P2Y12 receptor 4NTJ
TM2 77 2.50x50 μ receptor 6DDE μ receptor 6DDE
TM2 78 2.51x51 μ receptor 6DDE P2Y12 receptor 4NTJ
TM2 79 2.52x52 μ receptor 6DDE μ receptor 6DDE
TM2 80 2.53x53 μ receptor 6DDE PAR1 3VW7
TM2 81 2.54x54 μ receptor 6DDE PAR1 3VW7
TM2 82 2.55x55 μ receptor 6DDE AT2 receptor 5UNG
TM2 83 2.56x56 μ receptor 6DDE μ receptor 6DDE
TM2 84 2.57x57 μ receptor 6DDE μ receptor 6DDE
TM2 85 2.58x58 μ receptor 6DDE μ receptor 6DDE
TM2 86 2.59x59 μ receptor 6DDE μ receptor 6DDE
TM2 87 2.60x60 μ receptor 6DDE PAF receptor 5ZKQ
TM2 88 2.61x61 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM2 89 2.62x62 μ receptor 6DDE CCR5 5UIW
TM2 90 2.63x63 μ receptor 6DDE PAR1 3VW7
TM2 91 2.64x64 μ receptor 6DDE US28 4XT1
TM2 92 2.65x65 μ receptor 6DDE PAR2 5NDD
TM2 93 2.66x66 μ receptor 6DDE P2Y1 receptor 4XNW
ECL1 94 - - - -
ECL1 95 - - - -
ECL1 96 - - - -
ECL1 97 - - - -
ECL1 98 - - - -
ECL1 99 - - - -
ECL1 100 - - - -
TM3 101 3.24x24 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 102 3.25x25 μ receptor 6DDE μ receptor 6DDE
TM3 103 3.26x26 μ receptor 6DDE μ receptor 6DDE
TM3 104 3.27x27 μ receptor 6DDE PAR1 3VW7
TM3 105 3.28x28 μ receptor 6DDE P2Y12 receptor 4NTJ
TM3 106 3.29x29 μ receptor 6DDE PAR1 3VW7
TM3 107 3.30x30 μ receptor 6DDE PAR1 3VW7
TM3 108 3.31x31 μ receptor 6DDE PAR2 5NDD
TM3 109 3.32x32 μ receptor 6DDE PAR1 3VW7
TM3 110 3.33x33 μ receptor 6DDE PAF receptor 5ZKQ
TM3 111 3.34x34 μ receptor 6DDE PAF receptor 5ZKQ
TM3 112 3.35x35 μ receptor 6DDE CCR5 5UIW
TM3 113 3.36x36 μ receptor 6DDE CCR5 5UIW
TM3 114 3.37x37 μ receptor 6DDE μ receptor 6DDE
TM3 115 3.38x38 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 116 3.39x39 μ receptor 6DDE μ receptor 6DDE
TM3 117 3.40x40 μ receptor 6DDE μ receptor 6DDE
TM3 118 3.41x41 μ receptor 6DDE μ receptor 6DDE
TM3 119 3.42x42 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 120 3.43x43 μ receptor 6DDE CCR5 5UIW
TM3 121 3.44x44 μ receptor 6DDE PAR1 3VW7
TM3 122 3.45x45 μ receptor 6DDE PAR1 3VW7
TM3 123 3.46x46 μ receptor 6DDE PAR1 3VW7
TM3 124 3.47x47 μ receptor 6DDE μ receptor 6DDE
TM3 125 3.48x48 μ receptor 6DDE PAR1 3VW7
TM3 126 3.49x49 μ receptor 6DDE μ receptor 6DDE
TM3 127 3.50x50 μ receptor 6DDE μ receptor 6DDE
TM3 128 3.51x51 μ receptor 6DDE μ receptor 6DDE
TM3 129 3.52x52 μ receptor 6DDE PAR1 3VW7
TM3 130 3.53x53 μ receptor 6DDE μ receptor 6DDE
TM3 131 3.54x54 μ receptor 6DDE PAR2 5NDD
TM3 132 3.55x55 μ receptor 6DDE PAR1 3VW7
TM3 133 3.56x56 μ receptor 6DDE - -
ICL2 134 34.50x50 - - - -
ICL2 135 34.51x51 CCR5 5UIW C5a1 receptor 5O9H
ICL2 136 34.52x52 CCR5 5UIW - -
ICL2 137 34.53x53 CCR5 5UIW P2Y1 receptor 4XNW
ICL2 138 34.54x54 CCR5 5UIW - -
ICL2 139 34.55x55 CCR5 5UIW C5a1 receptor 6C1R
ICL2 140 34.56x56 CCR5 5UIW - -
ICL2 141 34.57x57 - - - -
TM4 142 4.38x38 μ receptor 6DDE μ receptor 6DDE
TM4 143 4.39x39 μ receptor 6DDE CCR5 5UIW
TM4 144 4.40x40 μ receptor 6DDE - -
TM4 145 4.41x41 μ receptor 6DDE Rhodopsin 5DYS
TM4 146 4.42x42 μ receptor 6DDE PAF receptor 5ZKQ
TM4 147 4.43x43 μ receptor 6DDE CCR5 5UIW
TM4 148 4.44x44 μ receptor 6DDE - -
TM4 149 4.45x45 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 150 4.46x46 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 151 4.47x47 μ receptor 6DDE PAR1 3VW7
TM4 152 4.48x48 μ receptor 6DDE CXCR4 3ODU
TM4 153 4.49x49 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 154 4.50x50 μ receptor 6DDE μ receptor 6DDE
TM4 155 4.51x51 μ receptor 6DDE PAR1 3VW7
TM4 156 4.52x52 μ receptor 6DDE PAF receptor 5ZKQ
TM4 157 4.53x53 μ receptor 6DDE PAR1 3VW7
TM4 158 4.54x54 μ receptor 6DDE PAR1 3VW7
TM4 159 4.55x55 μ receptor 6DDE P2Y12 receptor 4NTJ
TM4 160 4.56x56 μ receptor 6DDE PAR2 5NDD
TM4 161 4.57x57 CCR5 5UIW PAF receptor 5ZKQ
TM4 162 4.58x59 CCR5 5UIW D4 receptor 5WIV
TM4 163 4.59x60 μ receptor 6DDE PAR1 3VW7
TM4 164 4.60x61 μ receptor 6DDE OX1 receptor 4ZJ8
TM4 165 4.61x62 μ receptor 6DDE μ receptor 6DDE
TM4 166 4.62x63 CCR5 5UIW US28 4XT1
TM4 167 4.63x64 CCR5 5UIW CCR5 5UIW
TM4 168 4.64x65 CCR5 5UIW CCR5 5UIW
ECL2 169 - - - -
ECL2 170 - - - -
ECL2 171 - - - -
ECL2 172 - - - -
ECL2 173 - - - -
ECL2 174 - - - -
ECL2 175 45.50x50 μ receptor 6DDE μ receptor 6DDE
ECL2 176 45.51x51 μ receptor 6DDE A2A receptor 4UHR
ECL2 177 45.52x52 μ receptor 6DDE - -
ECL2 178 - - - -
ECL2 179 AT2 receptor 5UNF - -
ECL2 180 AT2 receptor 5UNF AT2 receptor 5UNF
ECL2 181 AT2 receptor 5UNF - -
ECL2 182 AT2 receptor 5UNF - -
ECL2 183 - - - -
TM5 184 5.31x32 CCR5 5UIW NOP receptor 5DHG
TM5 185 5.32x33 CCR5 5UIW - -
TM5 186 5.33x34 μ receptor 6DDE OX2 receptor 5WS3
TM5 187 5.34x35 μ receptor 6DDE μ receptor 6DDE
TM5 188 5.35x36 μ receptor 6DDE US28 4XT1
TM5 189 5.36x37 μ receptor 6DDE CXCR4 3ODU
TM5 190 5.37x38 μ receptor 6DDE μ receptor 6DDE
TM5 191 5.38x39 μ receptor 6DDE - -
TM5 192 5.39x40 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 193 5.40x41 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM5 194 5.41x42 μ receptor 6DDE US28 4XT1
TM5 195 5.42x43 μ receptor 6DDE P2Y1 receptor 4XNW
TM5 196 5.43x44 μ receptor 6DDE CCR2 5T1A
TM5 197 5.44x45 μ receptor 6DDE PAF receptor 5ZKQ
TM5 198 5.45x46 μ receptor 6DDE FFA1 receptor 5TZY
TM5 199 5.46x461 μ receptor 6DDE CCR5 5UIW
TM5 200 5.47x47 μ receptor 6DDE μ receptor 6DDE
TM5 201 5.48x48 μ receptor 6DDE PAR2 5NDD
TM5 202 5.49x49 μ receptor 6DDE PAF receptor 5ZKQ
TM5 203 5.50x50 μ receptor 6DDE μ receptor 6DDE
TM5 204 5.51x51 μ receptor 6DDE PAR1 3VW7
TM5 205 5.52x52 μ receptor 6DDE PAF receptor 5ZKQ
TM5 206 5.53x53 μ receptor 6DDE μ receptor 6DDE
TM5 207 5.54x54 μ receptor 6DDE 5-HT2B receptor 4IB4
TM5 208 5.55x55 μ receptor 6DDE NTS1 receptor 4XES
TM5 209 5.56x56 μ receptor 6DDE US28 4XT1
TM5 210 5.57x57 μ receptor 6DDE μ receptor 6DDE
TM5 211 5.58x58 μ receptor 6DDE μ receptor 6DDE
TM5 212 5.59x59 μ receptor 6DDE 5-HT2B receptor 4IB4
TM5 213 5.60x60 μ receptor 6DDE 5-HT1B receptor 5V54
TM5 214 5.61x61 μ receptor 6DDE PAR1 3VW7
TM5 215 5.62x62 μ receptor 6DDE μ receptor 6DDE
TM5 216 5.63x63 μ receptor 6DDE apelin receptor 5VBL
TM5 217 5.64x64 μ receptor 6DDE PAF receptor 5ZKQ
TM5 218 5.65x65 μ receptor 6DDE μ receptor 6DDE
TM5 219 5.66x66 μ receptor 6DDE - -
TM5 220 5.67x67 μ receptor 6DDE μ receptor 6DDE
TM5 221 5.68x68 μ receptor 6DDE - -
ICL3 222 - - - -
ICL3 223 - - - -
ICL3 224 - - - -
ICL3 225 - - - -
TM6 226 6.30x30 μ receptor 6DDE PAR1 3VW7
TM6 227 6.31x31 μ receptor 6DDE - -
TM6 228 6.32x32 μ receptor 6DDE PAR2 5NDD
TM6 229 6.33x33 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM6 230 6.34x34 μ receptor 6DDE - -
TM6 231 6.35x35 μ receptor 6DDE 5-HT1B receptor 5V54
TM6 232 6.36x36 μ receptor 6DDE CCR5 5UIW
TM6 233 6.37x37 μ receptor 6DDE CCR5 5UIW
TM6 234 6.38x38 μ receptor 6DDE μ receptor 6DDE
TM6 235 6.39x39 μ receptor 6DDE CB1 receptor 5XRA
TM6 236 6.40x40 μ receptor 6DDE μ receptor 6DDE
TM6 237 6.41x41 μ receptor 6DDE μ receptor 6DDE
TM6 238 6.42x42 μ receptor 6DDE P2Y12 receptor 4NTJ
TM6 239 6.43x43 μ receptor 6DDE μ receptor 6DDE
TM6 240 6.44x44 μ receptor 6DDE μ receptor 6DDE
TM6 241 6.45x45 μ receptor 6DDE PAR1 3VW7
TM6 242 6.46x46 μ receptor 6DDE PAR2 5NDD
TM6 243 6.47x47 μ receptor 6DDE CCR5 5UIW
TM6 244 6.48x48 μ receptor 6DDE μ receptor 6DDE
TM6 245 6.49x49 μ receptor 6DDE PAR2 5NDD
TM6 246 6.50x50 μ receptor 6DDE μ receptor 6DDE
TM6 247 6.51x51 μ receptor 6DDE NTS1 receptor 4XES
TM6 248 6.52x52 μ receptor 6DDE PAR1 3VW7
TM6 249 6.53x53 μ receptor 6DDE PAR1 3VW7
TM6 250 6.54x54 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 251 6.55x55 μ receptor 6DDE CCR2 5T1A
TM6 252 6.56x56 μ receptor 6DDE US28 4XT1
TM6 253 6.57x57 μ receptor 6DDE CCR5 5UIW
TM6 254 6.58x58 μ receptor 6DDE κ receptor 4DJH
TM6 255 6.59x59 μ receptor 6DDE PAF receptor 5ZKQ
TM6 256 6.60x60 μ receptor 6DDE PAF receptor 5ZKQ
TM6 257 6.61x61 μ receptor 6DDE - -
TM6 258 6.62x62 CCR2 5T1A PAR1 3VW7
TM6 259 6.63x63 CCR2 5T1A CCR9 5LWE
TM6 260 6.64x64 CCR2 5T1A P2Y1 receptor 4XNW
ECL3 261 - - - -
ECL3 262 AT1 receptor 4ZUD - -
ECL3 263 - - - -
TM7 264 7.24x23 CCR5 5UIW US28 5WB1
TM7 265 7.25x24 CCR5 5UIW CCR5 5UIW
TM7 266 7.26x25 CCR5 5UIW apelin receptor 5VBL
TM7 267 7.27x26 CCR5 5UIW - -
TM7 268 7.28x27 CCR5 5UIW OX1 receptor 4ZJ8
TM7 269 7.29x28 CCR5 5UIW 5-HT2C receptor 6BQH
TM7 270 7.30x29 μ receptor 6DDE S1P1 receptor 3V2Y
TM7 271 7.31x30 μ receptor 6DDE P2Y12 receptor 4NTJ
TM7 272 7.32x31 μ receptor 6DDE LPA6 receptor 5XSZ
TM7 273 7.33x32 μ receptor 6DDE AT2 receptor 5UNG
TM7 274 7.34x33 μ receptor 6DDE PAR1 3VW7
TM7 275 7.35x34 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 276 7.36x35 μ receptor 6DDE CXCR4 3ODU
TM7 277 7.37x36 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 278 7.38x37 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 279 7.39x38 μ receptor 6DDE CCR5 5UIW
TM7 280 7.40x39 μ receptor 6DDE CCR5 5UIW
TM7 281 7.41x40 μ receptor 6DDE PAR1 3VW7
TM7 282 7.42x41 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 283 7.43x42 μ receptor 6DDE US28 4XT1
TM7 284 7.44x43 μ receptor 6DDE LPA6 receptor 5XSZ
TM7 285 7.45x45 μ receptor 6DDE CCR5 5UIW
TM7 286 7.46x46 μ receptor 6DDE PAR1 3VW7
TM7 287 7.47x47 μ receptor 6DDE μ receptor 6DDE
TM7 288 7.48x48 μ receptor 6DDE μ receptor 6DDE
TM7 289 7.49x49 μ receptor 6DDE μ receptor 6DDE
TM7 290 7.50x50 μ receptor 6DDE μ receptor 6DDE
TM7 291 7.51x51 μ receptor 6DDE PAR1 3VW7
TM7 292 7.52x52 μ receptor 6DDE PAR1 3VW7
TM7 293 7.53x53 μ receptor 6DDE μ receptor 6DDE
TM7 294 7.54x54 μ receptor 6DDE μ receptor 6DDE
TM7 295 7.55x55 CCR5 5UIW CCR5 5UIW
TM7 296 7.56x56 CCR5 5UIW C5a1 receptor 5O9H
H8 297 8.47x47 CCR5 5UIW CCR5 5UIW
H8 298 8.48x48 CCR5 5UIW 5-HT1B receptor 4IAQ
H8 299 8.49x49 CCR5 5UIW CCR2 5T1A
H8 300 8.50x50 CCR5 5UIW P2Y12 receptor 4NTJ
H8 301 8.51x51 CCR5 5UIW P2Y12 receptor 4NTJ
H8 302 8.52x52 CCR5 5UIW CCR2 5T1A
H8 303 8.53x53 CCR5 5UIW CCR5 5UIW
H8 304 8.54x54 CCR5 5UIW CCR5 5UIW
H8 305 8.55x55 CCR5 5UIW - -
H8 306 8.56x56 CCR5 5UIW M4 receptor 5DSG
H8 307 8.57x57 CCR5 5UIW 5-HT1B receptor 4IAQ
H8 308 8.58x58 CCR5 5UIW - -
C-term 309 - - - -
C-term 310 - - - -
C-term 311 - - - -
C-term 312 - - - -
C-term 313 - - - -