CXCR6 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 7.2 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 48%) PDB: 6DDE

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 77.4 16.5 6.1
Side-chains 20.9 58.6 20.5

Number of backbone templates: 6
Number of rotamer templates: 33

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5LWE
6DDE
4ZUD
3ODU
5X33
4N6H
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 21 CCR9 5LWE CCR9 5LWE
N-term 22 CCR9 5LWE CCR9 5LWE
N-term 23 CCR9 5LWE CCR9 5LWE
N-term 24 CCR9 5LWE CCR9 5LWE
N-term 25 CCR9 5LWE CCR9 5LWE
TM1 26 1.27x27 CCR9 5LWE - -
TM1 27 1.28x28 CCR9 5LWE US28 4XT1
TM1 28 1.29x29 CCR9 5LWE CCR9 5LWE
TM1 29 1.30x30 CCR9 5LWE CCR9 5LWE
TM1 30 1.31x31 μ receptor 6DDE NTS1 receptor 4XES
TM1 31 1.32x32 μ receptor 6DDE NTS1 receptor 4XES
TM1 32 1.33x33 μ receptor 6DDE PAR2 5NDD
TM1 33 1.34x34 μ receptor 6DDE PAR1 3VW7
TM1 34 1.35x35 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 35 1.36x36 μ receptor 6DDE PAR1 3VW7
TM1 36 1.37x37 μ receptor 6DDE - -
TM1 37 1.38x38 μ receptor 6DDE - -
TM1 38 1.39x39 μ receptor 6DDE μ receptor 6DDE
TM1 39 1.40x40 μ receptor 6DDE NTS1 receptor 4XES
TM1 40 1.41x41 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 41 1.42x42 μ receptor 6DDE μ receptor 6DDE
TM1 42 1.43x43 μ receptor 6DDE PAR1 3VW7
TM1 43 1.44x44 μ receptor 6DDE PAR1 3VW7
TM1 44 1.45x45 μ receptor 6DDE - -
TM1 45 1.46x46 μ receptor 6DDE μ receptor 6DDE
TM1 46 1.47x47 μ receptor 6DDE PAR1 3VW7
TM1 47 1.48x48 μ receptor 6DDE NTS1 receptor 4XES
TM1 48 1.49x49 μ receptor 6DDE μ receptor 6DDE
TM1 49 1.50x50 μ receptor 6DDE μ receptor 6DDE
TM1 50 1.51x51 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 51 1.52x52 μ receptor 6DDE μ receptor 6DDE
TM1 52 1.53x53 μ receptor 6DDE μ receptor 6DDE
TM1 53 1.54x54 μ receptor 6DDE PAR2 5NDD
TM1 54 1.55x55 μ receptor 6DDE PAR1 3VW7
TM1 55 1.56x56 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 56 1.57x57 μ receptor 6DDE - -
TM1 57 1.58x58 μ receptor 6DDE PAR1 3VW7
TM1 58 1.59x59 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 59 1.60x60 μ receptor 6DDE μ receptor 6DDE
ICL1 60 12.48x48 - - - -
ICL1 61 12.49x49 AT1 receptor 4ZUD 5-HT2B receptor 4NC3
ICL1 62 12.50x50 AT1 receptor 4ZUD AT1 receptor 4ZUD
ICL1 63 12.51x51 - - - -
TM2 64 2.37x37 CCR9 5LWE P2Y1 receptor 4XNW
TM2 65 2.38x38 μ receptor 6DDE CCR2 5T1A
TM2 66 2.39x39 μ receptor 6DDE μ receptor 6DDE
TM2 67 2.40x40 μ receptor 6DDE CCR9 5LWE
TM2 68 2.41x41 μ receptor 6DDE PAR1 3VW7
TM2 69 2.42x42 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 70 2.43x43 μ receptor 6DDE NTS1 receptor 4XES
TM2 71 2.44x44 μ receptor 6DDE PAF receptor 5ZKQ
TM2 72 2.45x45 μ receptor 6DDE μ receptor 6DDE
TM2 73 2.46x46 μ receptor 6DDE μ receptor 6DDE
TM2 74 2.47x47 μ receptor 6DDE - -
TM2 75 2.48x48 μ receptor 6DDE μ receptor 6DDE
TM2 76 2.49x49 μ receptor 6DDE μ receptor 6DDE
TM2 77 2.50x50 μ receptor 6DDE μ receptor 6DDE
TM2 78 2.51x51 μ receptor 6DDE PAR2 5NDD
TM2 79 2.52x52 μ receptor 6DDE β2-adrenoceptor 3SN6
TM2 80 2.53x53 μ receptor 6DDE PAR1 3VW7
TM2 81 2.54x54 μ receptor 6DDE PAR1 3VW7
TM2 82 2.55x55 μ receptor 6DDE US28 4XT1
TM2 83 2.56x56 μ receptor 6DDE μ receptor 6DDE
TM2 84 2.57x57 μ receptor 6DDE μ receptor 6DDE
TM2 85 2.58x58 μ receptor 6DDE μ receptor 6DDE
TM2 86 2.59x59 μ receptor 6DDE μ receptor 6DDE
TM2 87 2.60x60 μ receptor 6DDE PAF receptor 5ZKQ
TM2 88 2.61x61 μ receptor 6DDE FFA1 receptor 5TZY
TM2 89 2.62x62 μ receptor 6DDE NTS1 receptor 4XES
TM2 90 2.63x63 μ receptor 6DDE CCR9 5LWE
TM2 91 2.64x64 μ receptor 6DDE - -
TM2 92 2.65x65 μ receptor 6DDE PAR2 5NDD
TM2 93 2.66x66 μ receptor 6DDE PAR2 5NDD
ECL1 94 23.49x49 - - - -
ECL1 95 23.50x50 CXCR4 3ODU CXCR4 3ODU
ECL1 96 23.51x51 CXCR4 3ODU CCR2 5T1A
ECL1 97 23.52x52 - - - -
TM3 98 3.21x21 μ receptor 6DDE μ receptor 6DDE
TM3 99 3.22x22 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM3 100 3.23x23 μ receptor 6DDE 5-HT2B receptor 4NC3
TM3 101 3.24x24 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 102 3.25x25 μ receptor 6DDE μ receptor 6DDE
TM3 103 3.26x26 μ receptor 6DDE μ receptor 6DDE
TM3 104 3.27x27 μ receptor 6DDE - -
TM3 105 3.28x28 μ receptor 6DDE PAR2 5NDD
TM3 106 3.29x29 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 107 3.30x30 μ receptor 6DDE PAR2 5NDD
TM3 108 3.31x31 μ receptor 6DDE μ receptor 6DDE
TM3 109 3.32x32 μ receptor 6DDE CCR9 5LWE
TM3 110 3.33x33 μ receptor 6DDE CXCR4 3ODU
TM3 111 3.34x34 μ receptor 6DDE PAF receptor 5ZKQ
TM3 112 3.35x35 μ receptor 6DDE μ receptor 6DDE
TM3 113 3.36x36 μ receptor 6DDE CCR9 5LWE
TM3 114 3.37x37 μ receptor 6DDE PAR1 3VW7
TM3 115 3.38x38 μ receptor 6DDE μ receptor 6DDE
TM3 116 3.39x39 μ receptor 6DDE μ receptor 6DDE
TM3 117 3.40x40 μ receptor 6DDE - -
TM3 118 3.41x41 μ receptor 6DDE PAR1 3VW7
TM3 119 3.42x42 μ receptor 6DDE CXCR4 3ODU
TM3 120 3.43x43 μ receptor 6DDE μ receptor 6DDE
TM3 121 3.44x44 μ receptor 6DDE PAR1 3VW7
TM3 122 3.45x45 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 123 3.46x46 μ receptor 6DDE PAR1 3VW7
TM3 124 3.47x47 μ receptor 6DDE PAF receptor 5ZKQ
TM3 125 3.48x48 μ receptor 6DDE μ receptor 6DDE
TM3 126 3.49x49 μ receptor 6DDE μ receptor 6DDE
TM3 127 3.50x50 μ receptor 6DDE μ receptor 6DDE
TM3 128 3.51x51 μ receptor 6DDE PAR1 3VW7
TM3 129 3.52x52 μ receptor 6DDE μ receptor 6DDE
TM3 130 3.53x53 μ receptor 6DDE Rhodopsin 5DYS
TM3 131 3.54x54 μ receptor 6DDE μ receptor 6DDE
TM3 132 3.55x55 μ receptor 6DDE PAR1 3VW7
TM3 133 3.56x56 μ receptor 6DDE 5-HT2B receptor 4IB4
ICL2 134 34.50x50 μ receptor 6DDE 5-HT1B receptor 4IAQ
ICL2 135 34.51x51 μ receptor 6DDE - -
ICL2 136 34.52x52 μ receptor 6DDE μ receptor 6DDE
ICL2 137 34.53x53 μ receptor 6DDE μ receptor 6DDE
ICL2 138 34.54x54 μ receptor 6DDE - -
ICL2 139 34.55x55 μ receptor 6DDE C5a1 receptor 6C1R
ICL2 140 34.56x56 μ receptor 6DDE - -
ICL2 141 34.57x57 μ receptor 6DDE - -
ICL2 142 34.58x58 - - - -
ICL2 143 - - - -
TM4 144 4.38x38 μ receptor 6DDE FFA1 receptor 5TZY
TM4 145 4.39x39 μ receptor 6DDE AT1 receptor 4ZUD
TM4 146 4.40x40 μ receptor 6DDE A2A receptor 4UHR
TM4 147 4.41x41 μ receptor 6DDE ETB receptor 5X93
TM4 148 4.42x42 μ receptor 6DDE PAF receptor 5ZKQ
TM4 149 4.43x43 μ receptor 6DDE μ receptor 6DDE
TM4 150 4.44x44 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM4 151 4.45x45 μ receptor 6DDE PAR1 3VW7
TM4 152 4.46x46 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 153 4.47x47 μ receptor 6DDE PAR1 3VW7
TM4 154 4.48x48 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 155 4.49x49 μ receptor 6DDE PAR1 3VW7
TM4 156 4.50x50 μ receptor 6DDE μ receptor 6DDE
TM4 157 4.51x51 μ receptor 6DDE PAF receptor 5ZKQ
TM4 158 4.52x52 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 159 4.53x53 μ receptor 6DDE μ receptor 6DDE
TM4 160 4.54x54 μ receptor 6DDE PAR2 5NDD
TM4 161 4.55x55 μ receptor 6DDE PAR2 5NDD
TM4 162 4.56x56 μ receptor 6DDE PAR2 5NDD
TM4 163 4.57x57 CCR9 5LWE P2Y12 receptor 4NTJ
TM4 164 4.58x59 CCR9 5LWE FFA1 receptor 5TZY
TM4 165 4.59x60 μ receptor 6DDE PAR1 3VW7
TM4 166 4.60x61 μ receptor 6DDE OX2 receptor 5WS3
TM4 167 4.61x62 μ receptor 6DDE PAF receptor 5ZKQ
TM4 168 4.62x63 CXCR4 3ODU CXCR4 3ODU
TM4 169 4.63x64 CXCR4 3ODU C5a1 receptor 5O9H
TM4 170 4.64x65 CXCR4 3ODU 5-HT2B receptor 4IB4
ECL2 171 μ receptor 6DDE - -
ECL2 172 μ receptor 6DDE - -
ECL2 173 μ receptor 6DDE - -
ECL2 174 μ receptor 6DDE - -
ECL2 175 μ receptor 6DDE - -
ECL2 176 μ receptor 6DDE - -
ECL2 177 μ receptor 6DDE - -
ECL2 178 μ receptor 6DDE - -
ECL2 179 μ receptor 6DDE μ receptor 6DDE
ECL2 180 45.50x50 μ receptor 6DDE μ receptor 6DDE
ECL2 181 45.51x51 μ receptor 6DDE CCR2 5T1A
ECL2 182 45.52x52 μ receptor 6DDE - -
ECL2 183 BLT1 receptor 5X33 BLT1 receptor 5X33
ECL2 184 - - - -
ECL2 185 BLT1 receptor 5X33 - -
TM5 186 5.33x34 μ receptor 6DDE NTS1 receptor 4XES
TM5 187 5.34x35 μ receptor 6DDE - -
TM5 188 5.35x36 μ receptor 6DDE AT2 receptor 5UNG
TM5 189 5.36x37 μ receptor 6DDE δ receptor 4N6H
TM5 190 5.37x38 μ receptor 6DDE NTS1 receptor 4XES
TM5 191 5.38x39 μ receptor 6DDE NTS1 receptor 4XES
TM5 192 5.39x40 μ receptor 6DDE BLT1 receptor 5X33
TM5 193 5.40x41 μ receptor 6DDE PAR1 3VW7
TM5 194 5.41x42 μ receptor 6DDE AT1 receptor 4ZUD
TM5 195 5.42x43 μ receptor 6DDE - -
TM5 196 5.43x44 μ receptor 6DDE US28 4XT1
TM5 197 5.44x45 μ receptor 6DDE apelin receptor 5VBL
TM5 198 5.45x46 μ receptor 6DDE FFA1 receptor 5TZY
TM5 199 5.46x461 μ receptor 6DDE CXCR4 3ODU
TM5 200 5.47x47 μ receptor 6DDE μ receptor 6DDE
TM5 201 5.48x48 μ receptor 6DDE PAR1 3VW7
TM5 202 5.49x49 μ receptor 6DDE PAF receptor 5ZKQ
TM5 203 5.50x50 μ receptor 6DDE μ receptor 6DDE
TM5 204 5.51x51 μ receptor 6DDE PAR1 3VW7
TM5 205 5.52x52 μ receptor 6DDE NTS1 receptor 4XES
TM5 206 5.53x53 μ receptor 6DDE C5a1 receptor 5O9H
TM5 207 5.54x54 μ receptor 6DDE 5-HT2B receptor 4IB4
TM5 208 5.55x55 μ receptor 6DDE 5-HT2B receptor 4IB4
TM5 209 5.56x56 μ receptor 6DDE μ receptor 6DDE
TM5 210 5.57x57 μ receptor 6DDE μ receptor 6DDE
TM5 211 5.58x58 μ receptor 6DDE μ receptor 6DDE
TM5 212 5.59x59 μ receptor 6DDE CCR5 5UIW
TM5 213 5.60x60 μ receptor 6DDE NTS1 receptor 4XES
TM5 214 5.61x61 μ receptor 6DDE PAR1 3VW7
TM5 215 5.62x62 μ receptor 6DDE μ receptor 6DDE
TM5 216 5.63x63 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 217 5.64x64 μ receptor 6DDE PAF receptor 5ZKQ
TM5 218 5.65x65 μ receptor 6DDE μ receptor 6DDE
TM5 219 5.66x66 μ receptor 6DDE PAF receptor 5ZKQ
TM5 220 5.67x67 μ receptor 6DDE CXCR4 3OE0
TM5 221 5.68x68 μ receptor 6DDE C5a1 receptor 5O9H
ICL3 222 - - - -
ICL3 223 - - - -
ICL3 224 - - - -
ICL3 225 - - - -
TM6 226 6.30x30 μ receptor 6DDE PAR1 3VW7
TM6 227 6.31x31 μ receptor 6DDE CCR9 5LWE
TM6 228 6.32x32 μ receptor 6DDE μ receptor 6DDE
TM6 229 6.33x33 μ receptor 6DDE - -
TM6 230 6.34x34 μ receptor 6DDE CCR9 5LWE
TM6 231 6.35x35 μ receptor 6DDE 5-HT1B receptor 5V54
TM6 232 6.36x36 μ receptor 6DDE AT1 receptor 4ZUD
TM6 233 6.37x37 μ receptor 6DDE CCR2 5T1A
TM6 234 6.38x38 μ receptor 6DDE CCR2 5T1A
TM6 235 6.39x39 μ receptor 6DDE A1 receptor 5UEN
TM6 236 6.40x40 μ receptor 6DDE μ receptor 6DDE
TM6 237 6.41x41 μ receptor 6DDE CCR2 5T1A
TM6 238 6.42x42 μ receptor 6DDE μ receptor 6DDE
TM6 239 6.43x43 μ receptor 6DDE μ receptor 6DDE
TM6 240 6.44x44 μ receptor 6DDE μ receptor 6DDE
TM6 241 6.45x45 μ receptor 6DDE 5-HT2B receptor 4IB4
TM6 242 6.46x46 μ receptor 6DDE PAR2 5NDD
TM6 243 6.47x47 μ receptor 6DDE M4 receptor 5DSG
TM6 244 6.48x48 μ receptor 6DDE CCR9 5LWE
TM6 245 6.49x49 μ receptor 6DDE apelin receptor 5VBL
TM6 246 6.50x50 μ receptor 6DDE μ receptor 6DDE
TM6 247 6.51x51 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 248 6.52x52 μ receptor 6DDE PAR1 3VW7
TM6 249 6.53x53 μ receptor 6DDE PAR2 5NDD
TM6 250 6.54x54 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 251 6.55x55 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 252 6.56x56 μ receptor 6DDE AT1 receptor 4ZUD
TM6 253 6.57x57 μ receptor 6DDE μ receptor 6DDE
TM6 254 6.58x58 μ receptor 6DDE - -
TM6 255 6.59x59 μ receptor 6DDE CXCR4 3ODU
TM6 256 6.60x60 μ receptor 6DDE ETB receptor 5X93
TM6 257 6.61x61 μ receptor 6DDE Rhodopsin 5DYS
ECL3 258 - - - -
ECL3 259 δ receptor 4N6H - -
ECL3 260 δ receptor 4N6H - -
ECL3 261 δ receptor 4N6H - -
ECL3 262 - - - -
TM7 263 7.28x27 CCR9 5LWE - -
TM7 264 7.29x28 CCR9 5LWE CCR9 5LWE
TM7 265 7.30x29 μ receptor 6DDE US28 4XT1
TM7 266 7.31x30 μ receptor 6DDE - -
TM7 267 7.32x31 μ receptor 6DDE NTS1 receptor 4XES
TM7 268 7.33x32 μ receptor 6DDE NTS1 receptor 4XES
TM7 269 7.34x33 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 270 7.35x34 μ receptor 6DDE CXCR4 3ODU
TM7 271 7.36x35 μ receptor 6DDE NTS1 receptor 4XES
TM7 272 7.37x36 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 273 7.38x37 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 274 7.39x38 μ receptor 6DDE CXCR4 3ODU
TM7 275 7.40x39 μ receptor 6DDE μ receptor 6DDE
TM7 276 7.41x40 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 277 7.42x41 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 278 7.43x42 μ receptor 6DDE μ receptor 6DDE
TM7 279 7.44x43 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 280 7.45x45 μ receptor 6DDE - -
TM7 281 7.46x46 μ receptor 6DDE P2Y12 receptor 4NTJ
TM7 282 7.47x47 μ receptor 6DDE μ receptor 6DDE
TM7 283 7.48x48 μ receptor 6DDE μ receptor 6DDE
TM7 284 7.49x49 μ receptor 6DDE μ receptor 6DDE
TM7 285 7.50x50 μ receptor 6DDE μ receptor 6DDE
TM7 286 7.51x51 μ receptor 6DDE μ receptor 6DDE
TM7 287 7.52x52 μ receptor 6DDE μ receptor 6DDE
TM7 288 7.53x53 μ receptor 6DDE μ receptor 6DDE
TM7 289 7.54x54 μ receptor 6DDE μ receptor 6DDE
TM7 290 7.55x55 CCR9 5LWE CCR9 5LWE
TM7 291 7.56x56 CCR9 5LWE CCR9 5LWE
H8 292 8.47x47 CCR9 5LWE PAR2 5NDD
H8 293 8.48x48 CCR9 5LWE - -
H8 294 8.49x49 CCR9 5LWE CCR2 5T1A
H8 295 8.50x50 CCR9 5LWE PAR2 5NDD
H8 296 8.51x51 CCR9 5LWE PAR2 5NDD
H8 297 8.52x52 CCR9 5LWE D3 receptor 3PBL
H8 298 8.53x53 CCR9 5LWE - -
H8 299 8.54x54 CCR9 5LWE 5-HT2B receptor 4IB4
H8 300 8.55x55 CCR9 5LWE - -
H8 301 8.56x56 CCR9 5LWE 5-HT1B receptor 4IAQ
H8 302 8.57x57 CCR9 5LWE 5-HT1B receptor 4IAQ
H8 303 8.58x58 CCR9 5LWE - -
H8 304 8.59x59 CCR9 5LWE CCR9 5LWE
H8 305 8.60x60 CCR9 5LWE A1 receptor 5UEN
H8 306 8.61x61 CCR9 5LWE - -
H8 307 8.62x62 CCR9 5LWE CCR9 5LWE
H8 308 8.63x63 CCR9 5LWE - -
H8 309 8.64x64 CCR9 5LWE - -
H8 310 8.65x65 CCR9 5LWE - -
H8 311 8.66x66 CCR9 5LWE - -
H8 312 8.67x67 CCR9 5LWE - -
C-term 313 - - - -
C-term 314 - - - -
C-term 315 - - - -
C-term 316 - - - -
C-term 317 - - - -