FFA3 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 7.21 docs)

VERSION

2018-07-10

MAIN TEMPLATE

PAR2 (sequence similarity: 49%) PDB: 5NDD

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 86.1 6.5 7.5
Side-chains 25.9 52.7 21.4

Number of backbone templates: 5
Number of rotamer templates: 37

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5NDD
5NDZ
5VBL
5TZY
5LWE
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 6 PAR2 5NDD PAR2 5NDD
N-term 7 PAR2 5NDD PAR2 5NDD
N-term 8 PAR2 5NDD PAR2 5NDD
N-term 9 PAR2 5NDD PAR2 5NDD
N-term 10 PAR2 5NDD PAR2 5NDD
TM1 11 1.29x29 PAR2 5NDD PAR1 3VW7
TM1 12 1.30x30 PAR2 5NDD NOP receptor 5DHG
TM1 13 1.31x31 PAR2 5NDD CXCR4 3ODU
TM1 14 1.32x32 PAR2 5NDD - -
TM1 15 1.33x33 PAR2 5NDD OX2 receptor 5WS3
TM1 16 1.34x34 PAR2 5NDD PAR2 5NDD
TM1 17 1.35x35 PAR2 5NDD PAR1 3VW7
TM1 18 1.36x36 PAR2 5NDD FFA1 receptor 5TZY
TM1 19 1.37x37 PAR2 5NDD PAR1 3VW7
TM1 20 1.38x38 PAR2 5NDD PAR2 5NDD
TM1 21 1.39x39 PAR2 5NDD PAR2 5NDD
TM1 22 1.40x40 PAR2 5NDD NTS1 receptor 4XES
TM1 23 1.41x41 PAR2 5NDD P2Y1 receptor 4XNW
TM1 24 1.42x42 PAR2 5NDD - -
TM1 25 1.43x43 PAR2 5NDD PAR2 5NDD
TM1 26 1.44x44 PAR2 5NDD 5-HT1B receptor 4IAQ
TM1 27 1.45x45 PAR2 5NDD PAR2 5NDD
TM1 28 1.46x46 PAR2 5NDD FFA1 receptor 5TZY
TM1 29 1.47x47 PAR2 5NDD PAR2 5NDD
TM1 30 1.48x48 PAR2 5NDD PAR2 5NDD
TM1 31 1.49x49 PAR2 5NDD PAR1 3VW7
TM1 32 1.50x50 PAR2 5NDD PAR2 5NDD
TM1 33 1.51x51 PAR2 5NDD Y1 receptor 5ZBH
TM1 34 1.52x52 PAR2 5NDD FFA1 receptor 5TZY
TM1 35 1.53x53 PAR2 5NDD PAR2 5NDD
TM1 36 1.54x54 PAR2 5NDD PAR2 5NDD
TM1 37 1.55x55 PAR2 5NDD PAR1 3VW7
TM1 38 1.56x56 PAR2 5NDD PAR2 5NDD
TM1 39 1.57x57 PAR2 5NDD PAR2 5NDD
TM1 40 1.58x58 PAR2 5NDD P2Y1 receptor 4XNW
TM1 41 1.59x59 PAR2 5NDD - -
TM1 42 1.60x60 PAR2 5NDD PAR1 3VW7
ICL1 43 - - - -
ICL1 44 apelin receptor 5VBL - -
ICL1 45 apelin receptor 5VBL - -
ICL1 46 apelin receptor 5VBL - -
ICL1 47 - - - -
TM2 48 2.37x37 PAR2 5NDD - -
TM2 49 2.38x38 PAR2 5NDD μ receptor 6DDE
TM2 50 2.39x39 PAR2 5NDD NTS1 receptor 4XES
TM2 51 2.40x40 PAR2 5NDD CXCR4 3ODU
TM2 52 2.41x41 PAR2 5NDD PAR1 3VW7
TM2 53 2.42x42 PAR2 5NDD 5-HT1B receptor 4IAQ
TM2 54 2.43x43 PAR2 5NDD P2Y12 receptor 4NTJ
TM2 55 2.44x44 PAR2 5NDD PAR1 3VW7
TM2 56 2.45x45 PAR2 5NDD PAR2 5NDD
TM2 57 2.46x46 PAR2 5NDD PAR2 5NDD
TM2 58 2.47x47 PAR2 5NDD PAF receptor 5ZKQ
TM2 59 2.48x48 PAR2 5NDD A2A receptor 4UHR
TM2 60 2.49x49 PAR2 5NDD FFA1 receptor 5TZY
TM2 61 2.50x50 PAR2 5NDD PAR2 5NDD
TM2 62 2.51x51 PAR2 5NDD PAR2 5NDD
TM2 63 2.52x52 PAR2 5NDD PAR2 5NDD
TM2 64 2.53x53 PAR2 5NDD FFA1 receptor 5TZY
TM2 65 2.54x54 PAR2 5NDD PAF receptor 5ZKQ
TM2 66 2.55x55 PAR2 5NDD P2Y1 receptor 4XNW
TM2 67 2.56x56 PAR2 5NDD - -
TM2 68 2.57x57 PAR2 5NDD PAR1 3VW7
TM2 69 2.58x58 PAR2 5NDD PAR2 5NDD
TM2 70 2.59x59 PAR2 5NDD PAR1 3VW7
TM2 71 2.60x60 PAR2 5NDD LPA6 receptor 5XSZ
TM2 72 2.61x61 PAR2 5NDD US28 4XT1
TM2 73 2.62x62 PAR2 5NDD FFA1 receptor 5TZY
TM2 74 2.63x63 PAR2 5NDD FFA1 receptor 5TZY
TM2 75 2.64x64 PAR2 5NDD FFA1 receptor 5TZY
TM2 76 2.65x65 PAR2 5NDD P2Y12 receptor 4NTJ
TM2 77 2.66x66 PAR2 5NDD P2Y1 receptor 4XNW
ECL1 78 - - - -
ECL1 79 PAR2 5NDZ - -
ECL1 80 23.49x49 PAR2 5NDZ C5a1 receptor 5O9H
ECL1 81 23.50x50 PAR2 5NDZ PAR2 5NDZ
ECL1 82 23.51x51 PAR2 5NDZ FFA1 receptor 5TZY
ECL1 83 23.52x52 - - - -
TM3 84 3.21x21 PAR2 5NDD FFA1 receptor 5TZY
TM3 85 3.22x22 PAR2 5NDD A1 receptor 5UEN
TM3 86 3.23x23 PAR2 5NDD μ receptor 5C1M
TM3 87 3.24x24 PAR2 5NDD PAR2 5NDD
TM3 88 3.25x25 PAR2 5NDD PAR2 5NDD
TM3 89 3.26x26 PAR2 5NDD FFA1 receptor 5TZY
TM3 90 3.27x27 PAR2 5NDD P2Y1 receptor 4XNW
TM3 91 3.28x28 PAR2 5NDD LPA6 receptor 5XSZ
TM3 92 3.29x29 PAR2 5NDD PAF receptor 5ZKQ
TM3 93 3.30x30 PAR2 5NDD P2Y1 receptor 4XNW
TM3 94 3.31x31 PAR2 5NDD P2Y1 receptor 4XNW
TM3 95 3.32x32 PAR2 5NDD PAR2 5NDD
TM3 96 3.33x33 PAR2 5NDD FFA1 receptor 5TZY
TM3 97 3.34x34 PAR2 5NDD 5-HT1B receptor 4IAQ
TM3 98 3.35x35 PAR2 5NDD P2Y12 receptor 4NTJ
TM3 99 3.36x36 PAR2 5NDD Y1 receptor 5ZBH
TM3 100 3.37x37 PAR2 5NDD PAR2 5NDD
TM3 101 3.38x38 PAR2 5NDD - -
TM3 102 3.39x39 PAR2 5NDD NTS1 receptor 4XES
TM3 103 3.40x40 PAR2 5NDD NTS1 receptor 4XES
TM3 104 3.41x41 PAR2 5NDD PAR2 5NDD
TM3 105 3.42x42 PAR2 5NDD PAR2 5NDD
TM3 106 3.43x43 PAR2 5NDD PAR2 5NDD
TM3 107 3.44x44 PAR2 5NDD FFA1 receptor 5TZY
TM3 108 3.45x45 PAR2 5NDD FFA1 receptor 5TZY
TM3 109 3.46x46 PAR2 5NDD - -
TM3 110 3.47x47 PAR2 5NDD PAR2 5NDD
TM3 111 3.48x48 PAR2 5NDD PAR1 3VW7
TM3 112 3.49x49 PAR2 5NDD NTS1 receptor 4XEE
TM3 113 3.50x50 PAR2 5NDD PAR2 5NDD
TM3 114 3.51x51 PAR2 5NDD PAR1 3VW7
TM3 115 3.52x52 PAR2 5NDD PAR1 3VW7
TM3 116 3.53x53 PAR2 5NDD AT2 receptor 5UNG
TM3 117 3.54x54 PAR2 5NDD PAR1 3VW7
TM3 118 3.55x55 PAR2 5NDD FFA1 receptor 5TZY
TM3 119 3.56x56 PAR2 5NDD μ receptor 6DDE
ICL2 120 34.50x50 - - - -
ICL2 121 34.51x51 FFA1 receptor 5TZY FFA1 receptor 5TZY
ICL2 122 34.52x52 FFA1 receptor 5TZY C5a1 receptor 5O9H
ICL2 123 34.53x53 FFA1 receptor 5TZY FFA1 receptor 5TZY
ICL2 124 34.54x54 FFA1 receptor 5TZY NTS1 receptor 4XES
ICL2 125 34.55x55 FFA1 receptor 5TZY NTS1 receptor 4XES
ICL2 126 34.56x56 FFA1 receptor 5TZY P2Y1 receptor 4XNW
ICL2 127 34.57x57 - - - -
TM4 128 4.38x38 PAR2 5NDD CCR9 5LWE
TM4 129 4.39x39 PAR2 5NDD PAR1 3VW7
TM4 130 4.40x40 PAR2 5NDD PAR1 3VW7
TM4 131 4.41x41 PAR2 5NDD US28 4XT1
TM4 132 4.42x42 PAR2 5NDD PAR2 5NDD
TM4 133 4.43x43 PAR2 5NDD M2 receptor 3UON
TM4 134 4.44x44 PAR2 5NDD δ receptor 4N6H
TM4 135 4.45x45 PAR2 5NDD FFA1 receptor 5TZY
TM4 136 4.46x46 PAR2 5NDD PAR2 5NDD
TM4 137 4.47x47 PAR2 5NDD P2Y1 receptor 4XNW
TM4 138 4.48x48 PAR2 5NDD PAR2 5NDD
TM4 139 4.49x49 PAR2 5NDD A2A receptor 4UHR
TM4 140 4.50x50 PAR2 5NDD PAR2 5NDD
TM4 141 4.51x51 PAR2 5NDD PAR2 5NDD
TM4 142 4.52x52 PAR2 5NDD PAR2 5NDD
TM4 143 4.53x53 PAR2 5NDD PAR1 3VW7
TM4 144 4.54x54 PAR2 5NDD μ receptor 5C1M
TM4 145 4.55x55 PAR2 5NDD PAR1 3VW7
TM4 146 4.56x56 PAR2 5NDD FFA1 receptor 5TZY
TM4 147 4.57x57 FFA1 receptor 5TZY CCR9 5LWE
TM4 148 4.58x58 FFA1 receptor 5TZY P2Y1 receptor 4XNW
TM4 149 4.59x59 FFA1 receptor 5TZY PAR1 3VW7
TM4 150 4.60x60 PAR2 5NDD FFA1 receptor 5TZY
TM4 151 4.61x61 PAR2 5NDD - -
TM4 152 4.62x62 PAR2 5NDD κ receptor 4DJH
TM4 153 4.63x63 PAR2 5NDD 5-HT2B receptor 4IB4
ECL2 154 PAR2 5NDD - -
ECL2 155 PAR2 5NDD - -
ECL2 156 PAR2 5NDD - -
ECL2 157 PAR2 5NDD - -
ECL2 158 PAR2 5NDD - -
ECL2 159 PAR2 5NDD - -
ECL2 160 PAR2 5NDD - -
ECL2 161 PAR2 5NDD - -
ECL2 162 PAR2 5NDD - -
ECL2 163 PAR2 5NDD - -
ECL2 164 PAR2 5NDD - -
ECL2 165 PAR2 5NDD - -
ECL2 166 PAR2 5NDD - -
ECL2 167 PAR2 5NDD - -
ECL2 168 - - - -
ECL2 169 45.50x50 PAR2 5NDD PAR2 5NDD
ECL2 170 45.51x51 PAR2 5NDD - -
ECL2 171 45.52x52 PAR2 5NDD - -
ECL2 172 PAR2 5NDD - -
ECL2 173 PAR2 5NDD - -
ECL2 174 PAR2 5NDD - -
ECL2 175 PAR2 5NDD - -
ECL2 176 PAR2 5NDD - -
ECL2 177 PAR2 5NDD PAR2 5NDD
TM5 178 5.32x33 PAR2 5NDD P2Y1 receptor 4XNW
TM5 179 5.33x34 PAR2 5NDD FFA1 receptor 5TZY
TM5 180 5.34x35 PAR2 5NDD - -
TM5 181 5.35x36 PAR2 5NDD NTS1 receptor 4BUO
TM5 182 5.36x37 PAR2 5NDD PAF receptor 5ZKQ
TM5 183 5.37x38 PAR2 5NDD FFA1 receptor 5TZY
TM5 184 5.38x39 PAR2 5NDD P2Y12 receptor 4NTJ
TM5 185 5.39x40 PAR2 5NDD FFA1 receptor 5TZY
TM5 186 5.40x41 PAR2 5NDD PAR2 5NDD
TM5 187 5.41x42 PAR2 5NDD US28 4XT1
TM5 188 5.42x43 PAR2 5NDD Rhodopsin 5DYS
TM5 189 5.43x44 PAR2 5NDD PAR2 5NDD
TM5 190 5.44x45 PAR2 5NDD PAR1 3VW7
TM5 191 5.45x46 PAR2 5NDD LPA6 receptor 5XSZ
TM5 192 5.46x461 PAR2 5NDD FFA1 receptor 5TZY
TM5 193 5.47x47 PAR2 5NDD PAR2 5NDD
TM5 194 5.48x48 PAR2 5NDD κ receptor 4DJH
TM5 195 5.49x49 PAR2 5NDD PAR1 3VW7
TM5 196 5.50x50 PAR2 5NDD PAR2 5NDD
TM5 197 5.51x51 PAR2 5NDD PAR1 3VW7
TM5 198 5.52x52 PAR2 5NDD PAR1 3VW7
TM5 199 5.53x53 PAR2 5NDD PAR1 3VW7
TM5 200 5.54x54 PAR2 5NDD PAR2 5NDD
TM5 201 5.55x55 PAR2 5NDD NTS1 receptor 4XES
TM5 202 5.56x56 PAR2 5NDD US28 4XT1
TM5 203 5.57x57 PAR2 5NDD PAR1 3VW7
TM5 204 5.58x58 PAR2 5NDD PAR2 5NDD
TM5 205 5.59x59 PAR2 5NDD NOP receptor 5DHG
TM5 206 5.60x60 PAR2 5NDD 5-HT1B receptor 5V54
TM5 207 5.61x61 PAR2 5NDD Rhodopsin 5DYS
TM5 208 5.62x62 PAR2 5NDD P2Y1 receptor 4XNW
TM5 209 5.63x63 PAR2 5NDD CB1 receptor 5XRA
TM5 210 5.64x64 PAR2 5NDD US28 4XT1
TM5 211 5.65x65 PAR2 5NDD PAR2 5NDD
TM5 212 5.66x66 - - - -
TM5 213 5.67x67 - - - -
TM5 214 5.68x68 - - - -
ICL3 215 - - - -
ICL3 216 - - - -
ICL3 217 - - - -
TM6 218 6.28x29 PAR2 5NDD FFA1 receptor 5TZR
TM6 219 6.29x30 PAR2 5NDD FFA1 receptor 5TZY
TM6 220 6.30x31 PAR2 5NDD 5-HT2B receptor 4IB4
TM6 221 6.31x32 PAR2 5NDD P2Y1 receptor 4XNW
TM6 222 6.32x33 PAR2 5NDD PAR2 5NDD
TM6 223 6.33x34 PAR2 5NDD NTS1 receptor 4XES
TM6 224 6.34x35 PAR2 5NDD FFA1 receptor 5TZY
TM6 225 6.35x36 PAR2 5NDD - -
TM6 226 6.36x37 PAR2 5NDD PAR2 5NDD
TM6 227 6.37x38 PAR2 5NDD μ receptor 6DDE
TM6 228 6.38x39 PAR2 5NDD PAR1 3VW7
TM6 229 6.39x40 PAR2 5NDD PAR1 3VW7
TM6 230 6.40x41 PAR2 5NDD - -
TM6 231 6.41x42 PAR2 5NDD FFA1 receptor 5TZY
TM6 232 6.42x43 PAR2 5NDD FFA1 receptor 5TZY
TM6 233 6.43x44 PAR2 5NDD - -
TM6 234 6.44x45 PAR2 5NDD PAR1 3VW7
TM6 235 6.45x46 PAR2 5NDD PAR2 5NDD
TM6 236 6.46x461 PAR2 5NDD P2Y1 receptor 4XNW
TM6 237 6.47x47 PAR2 5NDD PAR2 5NDD
TM6 238 6.48x48 PAR2 5NDD PAR2 5NDD
TM6 239 6.49x49 PAR2 5NDD PAR1 3VW7
TM6 240 6.50x50 PAR2 5NDD PAR2 5NDD
TM6 241 6.51x51 PAR2 5NDD FFA1 receptor 5TZY
TM6 242 6.52x52 PAR2 5NDD PAR2 5NDD
TM6 243 6.53x53 PAR2 5NDD PAR1 3VW7
TM6 244 6.54x54 PAR2 5NDD FFA1 receptor 5TZY
TM6 245 6.55x55 PAR2 5NDD D2 receptor 6CM4
TM6 246 6.56x56 PAR2 5NDD PAR2 5NDD
TM6 247 6.57x57 PAR2 5NDD PAR2 5NDD
TM6 248 6.58x58 PAR2 5NDD - -
TM6 249 6.59x59 PAR2 5NDD PAR2 5NDD
TM6 250 6.60x60 PAR2 5NDD 5-HT1B receptor 4IAQ
TM6 251 6.61x61 PAR2 5NDD D2 receptor 6CM4
ECL3 252 - - - -
ECL3 253 - - - -
ECL3 254 - - - -
ECL3 255 - - - -
TM7 256 7.33x32 PAR2 5NDD PAR2 5NDD
TM7 257 7.34x33 PAR2 5NDD FFA1 receptor 5TZY
TM7 258 7.35x34 PAR2 5NDD FFA1 receptor 5TZY
TM7 259 7.36x35 PAR2 5NDD PAR2 5NDD
TM7 260 7.37x36 PAR2 5NDD apelin receptor 5VBL
TM7 261 7.38x37 PAR2 5NDD D4 receptor 5WIV
TM7 262 7.39x38 PAR2 5NDD 5-HT1B receptor 4IAQ
TM7 263 7.40x39 PAR2 5NDD AT2 receptor 5UNG
TM7 264 7.41x40 PAR2 5NDD PAR2 5NDD
TM7 265 7.42x41 PAR2 5NDD PAR2 5NDD
TM7 266 7.43x42 PAR2 5NDD PAR2 5NDD
TM7 267 7.44x43 PAR2 5NDD PAR2 5NDD
TM7 268 7.45x45 PAR2 5NDD PAR2 5NDD
TM7 269 7.46x46 PAR2 5NDD PAR2 5NDD
TM7 270 7.47x47 PAR2 5NDD PAR2 5NDD
TM7 271 7.48x48 PAR2 5NDD P2Y1 receptor 4XNW
TM7 272 7.49x49 PAR2 5NDD PAR2 5NDD
TM7 273 7.50x50 PAR2 5NDD PAR2 5NDD
TM7 274 7.51x51 PAR2 5NDD PAR2 5NDD
TM7 275 7.52x52 PAR2 5NDD PAR2 5NDD
TM7 276 7.53x53 PAR2 5NDD PAR2 5NDD
TM7 277 7.54x54 PAR2 5NDD PAR2 5NDD
TM7 278 7.55x55 PAR2 5NDD PAR2 5NDD
TM7 279 7.56x56 PAR2 5NDD 5-HT1B receptor 4IAQ
H8 280 8.47x47 PAR2 5NDD PAR2 5NDD
H8 281 8.48x48 PAR2 5NDD - -
H8 282 8.49x49 PAR2 5NDD - -
H8 283 8.50x50 PAR2 5NDD PAR2 5NDD
H8 284 8.51x51 PAR2 5NDD AT2 receptor 5UNF
H8 285 8.52x52 PAR2 5NDD NOP receptor 5DHG
H8 286 8.53x53 PAR2 5NDD CCR9 5LWE
H8 287 8.54x54 PAR2 5NDD 5-HT2B receptor 4IB4
H8 288 8.55x55 PAR2 5NDD 5-HT1B receptor 4IAQ
H8 289 8.56x56 PAR2 5NDD β2-adrenoceptor 3SN6
H8 290 8.57x57 PAR2 5NDD 5-HT1B receptor 4IAQ
H8 291 8.58x58 PAR2 5NDD PAR2 5NDD
H8 292 8.59x59 CCR9 5LWE A2A receptor 4UHR
H8 293 8.60x60 CCR9 5LWE - -
H8 294 8.61x61 CCR9 5LWE CCR9 5LWE
C-term 295 - - - -
C-term 296 - - - -
C-term 297 - - - -
C-term 298 - - - -
C-term 299 - - - -