FFA4 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 9.54 docs)

VERSION

2018-07-10

MAIN TEMPLATE

κ receptor (sequence similarity: 40%) PDB: 6B73

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 73.3 18.0 8.7
Side-chains 17.0 51.4 31.5

Number of backbone templates: 7
Number of rotamer templates: 36

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6B73
5O9H
5WS3
4XES
3SN6
4XNW
4N6H
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 34 - - - -
N-term 35 - - - -
N-term 36 κ receptor 6B73 κ receptor 6B73
N-term 37 κ receptor 6B73 κ receptor 6B73
N-term 38 κ receptor 6B73 κ receptor 6B73
TM1 39 1.31x31 κ receptor 6B73 δ receptor 4N6H
TM1 40 1.32x32 κ receptor 6B73 μ receptor 5C1M
TM1 41 1.33x33 κ receptor 6B73 A1 receptor 6D9H
TM1 42 1.34x34 κ receptor 6B73 A2A receptor 5G53
TM1 43 1.35x35 κ receptor 6B73 - -
TM1 44 1.36x36 κ receptor 6B73 κ receptor 6B73
TM1 45 1.37x37 κ receptor 6B73 A2A receptor 5G53
TM1 46 1.38x38 κ receptor 6B73 κ receptor 6B73
TM1 47 1.39x39 κ receptor 6B73 5-HT2B receptor 5TUD
TM1 48 1.40x40 κ receptor 6B73 5-HT2C receptor 6BQG
TM1 49 1.41x41 κ receptor 6B73 5-HT2B receptor 5TUD
TM1 50 1.42x42 κ receptor 6B73 β2-adrenoceptor 3SN6
TM1 51 1.43x43 κ receptor 6B73 κ receptor 6B73
TM1 52 1.44x44 κ receptor 6B73 D2 receptor 6CM4
TM1 53 1.45x45 κ receptor 6B73 κ receptor 6B73
TM1 54 1.46x46 κ receptor 6B73 A1 receptor 6D9H
TM1 55 1.47x47 κ receptor 6B73 κ receptor 6B73
TM1 56 1.48x48 κ receptor 6B73 AT2 receptor 5UNG
TM1 57 1.49x49 κ receptor 6B73 κ receptor 6B73
TM1 58 1.50x50 κ receptor 6B73 κ receptor 6B73
TM1 59 1.51x51 κ receptor 6B73 β2-adrenoceptor 3SN6
TM1 60 1.52x52 κ receptor 6B73 - -
TM1 61 1.53x53 κ receptor 6B73 LPA6 receptor 5XSZ
TM1 62 1.54x54 κ receptor 6B73 NTS1 receptor 5T04
TM1 63 1.55x55 κ receptor 6B73 M2 receptor 4MQT
TM1 64 1.56x56 κ receptor 6B73 AT2 receptor 5UNG
TM1 65 1.57x57 κ receptor 6B73 5-HT2B receptor 5TUD
TM1 66 1.58x58 κ receptor 6B73 β2-adrenoceptor 3SN6
TM1 67 1.59x59 κ receptor 6B73 μ receptor 5C1M
TM1 68 1.60x60 κ receptor 6B73 US28 4XT1
ICL1 69 - - - -
ICL1 70 C5a1 receptor 5O9H - -
ICL1 71 - - - -
TM2 72 2.37x37 κ receptor 6B73 - -
TM2 73 2.38x38 κ receptor 6B73 κ receptor 6B73
TM2 74 2.39x39 κ receptor 6B73 κ receptor 6B73
TM2 75 2.40x40 κ receptor 6B73 C5a1 receptor 5O9H
TM2 76 2.41x41 κ receptor 6B73 A1 receptor 6D9H
TM2 77 2.42x42 κ receptor 6B73 5-HT1B receptor 6G79
TM2 78 2.43x43 κ receptor 6B73 A2A receptor 5G53
TM2 79 2.44x44 κ receptor 6B73 Rhodopsin 5DYS
TM2 80 2.45x45 κ receptor 6B73 κ receptor 6B73
TM2 81 2.46x46 κ receptor 6B73 κ receptor 6B73
TM2 82 2.47x47 κ receptor 6B73 - -
TM2 83 2.48x48 κ receptor 6B73 β2-adrenoceptor 3SN6
TM2 84 2.49x49 κ receptor 6B73 κ receptor 6B73
TM2 85 2.50x50 κ receptor 6B73 κ receptor 6B73
TM2 86 2.51x51 κ receptor 6B73 5-HT2B receptor 5TUD
TM2 87 2.52x52 κ receptor 6B73 κ receptor 6B73
TM2 88 2.53x53 κ receptor 6B73 LPA6 receptor 5XSZ
TM2 89 2.54x54 κ receptor 6B73 ETB receptor 5X93
TM2 90 2.55x55 κ receptor 6B73 μ receptor 5C1M
TM2 91 2.56x56 κ receptor 6B73 NTS1 receptor 5T04
TM2 92 2.57x57 κ receptor 6B73 A1 receptor 6D9H
TM2 93 2.58x58 κ receptor 6B73 κ receptor 6B73
TM2 94 2.59x59 κ receptor 6B73 5-HT2C receptor 6BQG
TM2 95 2.60x60 κ receptor 6B73 D2 receptor 6CM4
TM2 96 2.61x61 κ receptor 6B73 5-HT2B receptor 5TUD
TM2 97 2.62x62 κ receptor 6B73 β2-adrenoceptor 3SN6
TM2 98 2.63x63 κ receptor 6B73 κ receptor 6B73
TM2 99 2.64x64 κ receptor 6B73 - -
TM2 100 2.65x65 κ receptor 6B73 - -
TM2 101 2.66x66 κ receptor 6B73 β2-adrenoceptor 3SN6
ECL1 102 - - - -
ECL1 103 23.49x49 OX2 receptor 5WS3 D4 receptor 5WIV
ECL1 104 23.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL1 105 23.51x51 OX2 receptor 5WS3 AT2 receptor 5UNG
ECL1 106 23.52x52 - - - -
TM3 107 3.21x21 κ receptor 6B73 κ receptor 6B73
TM3 108 3.22x22 κ receptor 6B73 AT2 receptor 5UNG
TM3 109 3.23x23 κ receptor 6B73 κ receptor 6B73
TM3 110 3.24x24 κ receptor 6B73 C5a1 receptor 5O9H
TM3 111 3.25x25 κ receptor 6B73 κ receptor 6B73
TM3 112 3.26x26 κ receptor 6B73 - -
TM3 113 3.27x27 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 114 3.28x28 κ receptor 6B73 US28 4XT1
TM3 115 3.29x29 κ receptor 6B73 - -
TM3 116 3.30x30 κ receptor 6B73 OX2 receptor 5WS3
TM3 117 3.31x31 κ receptor 6B73 Y1 receptor 5ZBH
TM3 118 3.32x32 κ receptor 6B73 S1P1 receptor 3V2Y
TM3 119 3.33x33 κ receptor 6B73 AT2 receptor 5UNG
TM3 120 3.34x34 κ receptor 6B73 5-HT2B receptor 5TUD
TM3 121 3.35x35 κ receptor 6B73 CB1 receptor 5XRA
TM3 122 3.36x36 κ receptor 6B73 Rhodopsin 5DYS
TM3 123 3.37x37 κ receptor 6B73 OX2 receptor 5WS3
TM3 124 3.38x38 κ receptor 6B73 OX2 receptor 5WS3
TM3 125 3.39x39 κ receptor 6B73 NTS1 receptor 5T04
TM3 126 3.40x40 κ receptor 6B73 κ receptor 6B73
TM3 127 3.41x41 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 128 3.42x42 κ receptor 6B73 κ receptor 6B73
TM3 129 3.43x43 κ receptor 6B73 κ receptor 6B73
TM3 130 3.44x44 κ receptor 6B73 NTS1 receptor 5T04
TM3 131 3.45x45 κ receptor 6B73 5-HT2B receptor 5TUD
TM3 132 3.46x46 κ receptor 6B73 - -
TM3 133 3.47x47 κ receptor 6B73 κ receptor 6B73
TM3 134 3.48x48 κ receptor 6B73 5-HT2C receptor 6BQG
TM3 135 3.49x49 κ receptor 6B73 NTS1 receptor 5T04
TM3 136 3.50x50 κ receptor 6B73 κ receptor 6B73
TM3 137 3.51x51 κ receptor 6B73 - -
TM3 138 3.52x52 κ receptor 6B73 5-HT2C receptor 6BQG
TM3 139 3.53x53 κ receptor 6B73 M2 receptor 4MQT
TM3 140 3.54x54 κ receptor 6B73 5-HT2B receptor 5TUD
TM3 141 3.55x55 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 142 3.56x56 κ receptor 6B73 κ receptor 6B73
ICL2 143 34.50x50 κ receptor 6B73 - -
ICL2 144 34.51x51 κ receptor 6B73 - -
ICL2 145 34.52x52 κ receptor 6B73 A1 receptor 6D9H
ICL2 146 34.53x53 κ receptor 6B73 - -
ICL2 147 34.54x54 κ receptor 6B73 - -
ICL2 148 34.55x55 κ receptor 6B73 Rhodopsin 4ZWJ
ICL2 149 34.56x56 κ receptor 6B73 D3 receptor 3PBL
ICL2 150 34.57x57 κ receptor 6B73 - -
TM4 151 4.38x38 κ receptor 6B73 Rhodopsin 5DYS
TM4 152 4.39x39 κ receptor 6B73 5-HT2B receptor 5TUD
TM4 153 4.40x40 κ receptor 6B73 μ receptor 5C1M
TM4 154 4.41x41 κ receptor 6B73 CXCR4 3ODU
TM4 155 4.42x42 κ receptor 6B73 - -
TM4 156 4.43x43 κ receptor 6B73 A1 receptor 6D9H
TM4 157 4.44x44 κ receptor 6B73 β2-adrenoceptor 3SN6
TM4 158 4.45x45 κ receptor 6B73 C5a1 receptor 5O9H
TM4 159 4.46x46 κ receptor 6B73 BLT1 receptor 5X33
TM4 160 4.47x47 κ receptor 6B73 5-HT2C receptor 6BQG
TM4 161 4.48x48 κ receptor 6B73 AT2 receptor 5UNG
TM4 162 4.49x49 κ receptor 6B73 κ receptor 6B73
TM4 163 4.50x50 κ receptor 6B73 κ receptor 6B73
TM4 164 4.51x51 κ receptor 6B73 C5a1 receptor 5O9H
TM4 165 4.52x52 κ receptor 6B73 - -
TM4 166 4.53x53 κ receptor 6B73 κ receptor 6B73
TM4 167 4.54x54 κ receptor 6B73 NTS1 receptor 5T04
TM4 168 4.55x55 κ receptor 6B73 A1 receptor 6D9H
TM4 169 4.56x56 κ receptor 6B73 PAF receptor 5ZKP
TM4 170 4.57x57 OX2 receptor 5WS3 5-HT2B receptor 5TUD
TM4 171 4.58x59 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
TM4 172 4.59x60 κ receptor 6B73 5-HT2B receptor 5TUD
TM4 173 4.60x61 κ receptor 6B73 Rhodopsin 5DYS
TM4 174 4.61x62 κ receptor 6B73 - -
TM4 175 4.62x63 κ receptor 6B73 5-HT2C receptor 6BQG
TM4 176 4.63x64 κ receptor 6B73 - -
TM4 177 4.64x65 OX2 receptor 5WS3 ETB receptor 5X93
ECL2 178 - - - -
ECL2 179 NTS1 receptor 4XES - -
ECL2 180 NTS1 receptor 4XES - -
ECL2 181 NTS1 receptor 4XES - -
ECL2 182 NTS1 receptor 4XES - -
ECL2 183 NTS1 receptor 4XES - -
ECL2 184 NTS1 receptor 4XES - -
ECL2 185 NTS1 receptor 4XES - -
ECL2 186 NTS1 receptor 4XES NTS1 receptor 4XES
ECL2 187 NTS1 receptor 4XES - -
ECL2 188 NTS1 receptor 4XES - -
ECL2 189 NTS1 receptor 4XES - -
ECL2 190 NTS1 receptor 4XES - -
ECL2 191 NTS1 receptor 4XES - -
ECL2 192 NTS1 receptor 4XES - -
ECL2 193 - - - -
ECL2 194 45.50x50 κ receptor 6B73 κ receptor 6B73
ECL2 195 45.51x51 κ receptor 6B73 NTS1 receptor 5T04
ECL2 196 45.52x52 κ receptor 6B73 κ receptor 6B73
ECL2 197 - - - -
ECL2 198 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL2 199 OX2 receptor 5WS3 - -
ECL2 200 OX2 receptor 5WS3 - -
ECL2 201 - - - -
TM5 202 5.33x34 κ receptor 6B73 - -
TM5 203 5.34x35 κ receptor 6B73 - -
TM5 204 5.35x36 κ receptor 6B73 μ receptor 5C1M
TM5 205 5.36x37 κ receptor 6B73 US28 4XT1
TM5 206 5.37x38 κ receptor 6B73 Rhodopsin 5DYS
TM5 207 5.38x39 κ receptor 6B73 - -
TM5 208 5.39x40 κ receptor 6B73 ETB receptor 5X93
TM5 209 5.40x41 κ receptor 6B73 A1 receptor 6D9H
TM5 210 5.41x42 κ receptor 6B73 apelin receptor 5VBL
TM5 211 5.42x43 κ receptor 6B73 OX2 receptor 5WS3
TM5 212 5.43x44 κ receptor 6B73 PAF receptor 5ZKP
TM5 213 5.44x45 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 214 5.45x46 κ receptor 6B73 AT2 receptor 5UNG
TM5 215 5.46x461 κ receptor 6B73 H1 receptor 3RZE
TM5 216 5.47x47 κ receptor 6B73 κ receptor 6B73
TM5 217 5.48x48 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 218 5.49x49 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 219 5.50x50 κ receptor 6B73 κ receptor 6B73
TM5 220 5.51x51 κ receptor 6B73 CXCR4 3ODU
TM5 221 5.52x52 κ receptor 6B73 κ receptor 6B73
TM5 222 5.53x53 κ receptor 6B73 NTS1 receptor 5T04
TM5 223 5.54x54 κ receptor 6B73 κ receptor 6B73
TM5 224 5.55x55 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 225 5.56x56 κ receptor 6B73 5-HT2C receptor 6BQG
TM5 226 5.57x57 κ receptor 6B73 AT1 receptor 4ZUD
TM5 227 5.58x58 κ receptor 6B73 κ receptor 6B73
TM5 228 5.59x59 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 229 5.60x60 κ receptor 6B73 H1 receptor 3RZE
TM5 230 5.61x61 κ receptor 6B73 AT2 receptor 5UNG
TM5 231 5.62x62 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 232 5.63x63 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 233 5.64x64 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 234 5.65x65 κ receptor 6B73 M2 receptor 4MQT
TM5 235 5.66x66 κ receptor 6B73 - -
TM5 236 5.67x67 κ receptor 6B73 CXCR4 3OE0
TM5 237 5.68x68 β2-adrenoceptor 3SN6 - -
TM5 238 5.69x69 β2-adrenoceptor 3SN6 β2-adrenoceptor 3SN6
TM5 239 5.70x70 β2-adrenoceptor 3SN6 - -
TM5 240 5.71x71 β2-adrenoceptor 3SN6 - -
TM5 241 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 242 5.73x73 β2-adrenoceptor 3SN6 - -
TM5 243 5.74x74 β2-adrenoceptor 3SN6 - -
TM5 244 5.75x75 β2-adrenoceptor 3SN6 - -
TM5 245 5.76x76 β2-adrenoceptor 3SN6 - -
ICL3 246 - - - -
ICL3 247 - - - -
ICL3 248 - - - -
ICL3 249 - - - -
ICL3 250 - - - -
ICL3 264 - - - -
ICL3 265 - - - -
ICL3 266 - - - -
ICL3 267 - - - -
ICL3 268 - - - -
TM6 269 6.24x25 κ receptor 6B73 - -
TM6 270 6.25x26 κ receptor 6B73 NTS1 receptor 5T04
TM6 271 6.26x27 κ receptor 6B73 NTS1 receptor 5T04
TM6 272 6.27x28 κ receptor 6B73 5-HT2B receptor 5TUD
TM6 273 6.28x29 κ receptor 6B73 ETB receptor 5X93
TM6 274 6.29x30 κ receptor 6B73 - -
TM6 275 6.30x31 κ receptor 6B73 AT2 receptor 5UNG
TM6 276 6.31x32 κ receptor 6B73 - -
TM6 277 6.32x33 κ receptor 6B73 PAF receptor 5ZKP
TM6 278 6.33x34 κ receptor 6B73 β2-adrenoceptor 4LDE
TM6 279 6.34x35 κ receptor 6B73 - -
TM6 280 6.35x36 κ receptor 6B73 - -
TM6 281 6.36x37 κ receptor 6B73 CXCR4 3ODU
TM6 282 6.37x38 κ receptor 6B73 κ receptor 6B73
TM6 283 6.38x39 κ receptor 6B73 H1 receptor 3RZE
TM6 284 6.39x40 κ receptor 6B73 apelin receptor 5VBL
TM6 285 6.40x41 κ receptor 6B73 LPA6 receptor 5XSZ
TM6 286 6.41x42 κ receptor 6B73 - -
TM6 287 6.42x43 κ receptor 6B73 κ receptor 6B73
TM6 288 6.43x44 κ receptor 6B73 - -
TM6 289 6.44x45 κ receptor 6B73 PAF receptor 5ZKP
TM6 290 6.45x46 P2Y1 receptor 4XNW LPA6 receptor 5XSZ
TM6 291 6.46x461 P2Y1 receptor 4XNW PAF receptor 5ZKP
TM6 292 6.47x47 P2Y1 receptor 4XNW 5-HT2B receptor 5TUD
TM6 293 6.48x48 κ receptor 6B73 κ receptor 6B73
TM6 294 6.49x49 κ receptor 6B73 - -
TM6 295 6.50x50 κ receptor 6B73 κ receptor 6B73
TM6 296 6.51x51 κ receptor 6B73 κ receptor 6B73
TM6 297 6.52x52 κ receptor 6B73 - -
TM6 298 6.53x53 κ receptor 6B73 κ receptor 6B73
TM6 299 6.54x54 κ receptor 6B73 5-HT2B receptor 5TUD
TM6 300 6.55x55 κ receptor 6B73 κ receptor 6B73
TM6 301 6.56x56 κ receptor 6B73 κ receptor 6B73
TM6 302 6.57x57 κ receptor 6B73 5-HT2C receptor 6BQG
TM6 303 6.58x58 κ receptor 6B73 Rhodopsin 5DYS
TM6 304 6.59x59 κ receptor 6B73 A1 receptor 6D9H
TM6 305 6.60x60 κ receptor 6B73 β2-adrenoceptor 3SN6
TM6 306 6.61x61 κ receptor 6B73 β2-adrenoceptor 4LDE
ECL3 307 - - - -
ECL3 308 δ receptor 4N6H - -
ECL3 309 δ receptor 4N6H - -
ECL3 310 δ receptor 4N6H - -
ECL3 311 - - - -
TM7 312 7.28x27 κ receptor 6B73 - -
TM7 313 7.29x28 κ receptor 6B73 - -
TM7 314 7.30x29 κ receptor 6B73 AT1 receptor 4ZUD
TM7 315 7.31x30 κ receptor 6B73 - -
TM7 316 7.32x31 κ receptor 6B73 Rhodopsin 5DYS
TM7 317 7.33x32 κ receptor 6B73 κ receptor 6B73
TM7 318 7.34x33 κ receptor 6B73 5-HT2B receptor 5TUD
TM7 319 7.35x34 κ receptor 6B73 5-HT1B receptor 6G79
TM7 320 7.36x35 κ receptor 6B73 - -
TM7 321 7.37x36 κ receptor 6B73 - -
TM7 322 7.38x37 κ receptor 6B73 D4 receptor 5WIV
TM7 323 7.39x38 κ receptor 6B73 5-HT2B receptor 5TUD
TM7 324 7.40x39 κ receptor 6B73 κ receptor 6B73
TM7 325 7.41x40 κ receptor 6B73 Rhodopsin 5DYS
TM7 326 7.42x41 κ receptor 6B73 A1 receptor 6D9H
TM7 327 7.43x42 κ receptor 6B73 AT2 receptor 5UNG
TM7 328 7.44x43 κ receptor 6B73 NTS1 receptor 5T04
TM7 329 7.45x45 κ receptor 6B73 κ receptor 6B73
TM7 330 7.46x46 κ receptor 6B73 κ receptor 6B73
TM7 331 7.47x47 κ receptor 6B73 NTS1 receptor 5T04
TM7 332 7.48x48 κ receptor 6B73 κ receptor 6B73
TM7 333 7.49x49 κ receptor 6B73 κ receptor 6B73
TM7 334 7.50x50 κ receptor 6B73 κ receptor 6B73
TM7 335 7.51x51 κ receptor 6B73 LPA6 receptor 5XSZ
TM7 336 7.52x52 OX2 receptor 5WS3 AT2 receptor 5UNG
TM7 337 7.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 338 7.54x54 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 339 7.55x55 OX2 receptor 5WS3 Rhodopsin 5DYS
TM7 340 7.56x56 OX2 receptor 5WS3 LPA6 receptor 5XSZ
H8 341 8.47x47 OX2 receptor 5WS3 - -
H8 342 8.48x48 OX2 receptor 5WS3 - -
H8 343 8.49x49 OX2 receptor 5WS3 AT2 receptor 5UNG
H8 344 8.50x50 OX2 receptor 5WS3 - -
H8 345 8.51x51 OX2 receptor 5WS3 - -
H8 346 8.52x52 OX2 receptor 5WS3 - -
H8 347 8.53x53 OX2 receptor 5WS3 AT2 receptor 5UNG
H8 348 8.54x54 OX2 receptor 5WS3 - -
H8 349 8.55x55 OX2 receptor 5WS3 S1P1 receptor 3V2Y
H8 350 8.56x56 OX2 receptor 5WS3 Y1 receptor 5ZBQ
H8 351 8.57x57 OX2 receptor 5WS3 - -
H8 352 8.58x58 OX2 receptor 5WS3 κ receptor 4DJH
C-term 353 - - - -
C-term 354 - - - -
C-term 355 - - - -
C-term 356 - - - -
C-term 357 - - - -