CCK2 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 9.79 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 49%) PDB: 5C1M

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 79.9 13.0 7.1
Side-chains 22.1 55.2 22.7

Number of backbone templates: 4
Number of rotamer templates: 38

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5C1M
5WS3
3SN6
5ZBH
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 48 μ receptor 5C1M μ receptor 5C1M
N-term 49 μ receptor 5C1M μ receptor 5C1M
N-term 50 μ receptor 5C1M μ receptor 5C1M
N-term 51 μ receptor 5C1M μ receptor 5C1M
N-term 52 μ receptor 5C1M μ receptor 5C1M
TM1 53 1.31x31 μ receptor 5C1M M2 receptor 4MQT
TM1 54 1.32x32 μ receptor 5C1M - -
TM1 55 1.33x33 μ receptor 5C1M A1 receptor 6D9H
TM1 56 1.34x34 μ receptor 5C1M κ receptor 6B73
TM1 57 1.35x35 μ receptor 5C1M - -
TM1 58 1.36x36 μ receptor 5C1M A2A receptor 5G53
TM1 59 1.37x37 μ receptor 5C1M A2A receptor 5G53
TM1 60 1.38x38 μ receptor 5C1M μ receptor 5C1M
TM1 61 1.39x39 μ receptor 5C1M μ receptor 5C1M
TM1 62 1.40x40 μ receptor 5C1M 5-HT1B receptor 6G79
TM1 63 1.41x41 μ receptor 5C1M κ receptor 6B73
TM1 64 1.42x42 μ receptor 5C1M β2-adrenoceptor 3SN6
TM1 65 1.43x43 μ receptor 5C1M κ receptor 6B73
TM1 66 1.44x44 μ receptor 5C1M β2-adrenoceptor 3SN6
TM1 67 1.45x45 μ receptor 5C1M 5-HT2C receptor 6BQG
TM1 68 1.46x46 μ receptor 5C1M A1 receptor 6D9H
TM1 69 1.47x47 μ receptor 5C1M β2-adrenoceptor 3SN6
TM1 70 1.48x48 μ receptor 5C1M 5-HT2B receptor 5TUD
TM1 71 1.49x49 μ receptor 5C1M μ receptor 5C1M
TM1 72 1.50x50 μ receptor 5C1M μ receptor 5C1M
TM1 73 1.51x51 μ receptor 5C1M CCR5 5UIW
TM1 74 1.52x52 μ receptor 5C1M μ receptor 5C1M
TM1 75 1.53x53 μ receptor 5C1M - -
TM1 76 1.54x54 μ receptor 5C1M β2-adrenoceptor 3SN6
TM1 77 1.55x55 μ receptor 5C1M M2 receptor 4MQT
TM1 78 1.56x56 μ receptor 5C1M μ receptor 5C1M
TM1 79 1.57x57 μ receptor 5C1M NTS1 receptor 4XES
TM1 80 1.58x58 μ receptor 5C1M CXCR4 3ODU
TM1 81 1.59x59 μ receptor 5C1M 5-HT2B receptor 5TUD
TM1 82 1.60x60 μ receptor 5C1M CB1 receptor 5XRA
ICL1 83 12.48x48 - - - -
ICL1 84 12.49x49 OX2 receptor 5WS3 β2-adrenoceptor 4LDE
ICL1 85 12.50x50 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
ICL1 86 12.51x51 - - - -
TM2 87 2.37x37 μ receptor 5C1M μ receptor 5C1M
TM2 88 2.38x38 μ receptor 5C1M β2-adrenoceptor 3SN6
TM2 89 2.39x39 μ receptor 5C1M μ receptor 5C1M
TM2 90 2.40x40 μ receptor 5C1M μ receptor 5C1M
TM2 91 2.41x41 μ receptor 5C1M - -
TM2 92 2.42x42 μ receptor 5C1M β2-adrenoceptor 3SN6
TM2 93 2.43x43 μ receptor 5C1M 5-HT2B receptor 5TUD
TM2 94 2.44x44 μ receptor 5C1M Rhodopsin 4ZWJ
TM2 95 2.45x45 μ receptor 5C1M β2-adrenoceptor 3SN6
TM2 96 2.46x46 μ receptor 5C1M μ receptor 5C1M
TM2 97 2.47x47 μ receptor 5C1M μ receptor 5C1M
TM2 98 2.48x48 μ receptor 5C1M 5-HT2B receptor 5TUD
TM2 99 2.49x49 μ receptor 5C1M LPA6 receptor 5XSZ
TM2 100 2.50x50 μ receptor 5C1M μ receptor 5C1M
TM2 101 2.51x51 μ receptor 5C1M β2-adrenoceptor 3SN6
TM2 102 2.52x52 μ receptor 5C1M μ receptor 5C1M
TM2 103 2.53x53 μ receptor 5C1M AT2 receptor 5UNG
TM2 104 2.54x54 μ receptor 5C1M Y1 receptor 5ZBH
TM2 105 2.55x55 OX2 receptor 5WS3 M2 receptor 4MQT
TM2 106 2.56x551 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
TM2 107 2.57x56 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 108 2.58x57 μ receptor 5C1M κ receptor 6B73
TM2 109 2.59x58 μ receptor 5C1M μ receptor 5C1M
TM2 110 2.60x59 μ receptor 5C1M μ receptor 5C1M
TM2 111 2.61x60 μ receptor 5C1M Rhodopsin 4ZWJ
TM2 112 2.62x61 μ receptor 5C1M 5-HT2B receptor 5TUD
TM2 113 2.63x62 μ receptor 5C1M 5-HT2B receptor 5TUD
TM2 114 2.64x63 μ receptor 5C1M - -
TM2 115 2.65x64 μ receptor 5C1M A1 receptor 6D9H
TM2 116 2.66x65 μ receptor 5C1M μ receptor 5C1M
TM2 117 2.67x66 μ receptor 5C1M μ receptor 5C1M
TM2 118 2.68x67 OX2 receptor 5WS3 μ receptor 6DDF
ECL1 119 23.49x49 - - - -
ECL1 120 23.50x50 OX2 receptor 5WS3 Rhodopsin 4ZWJ
ECL1 121 23.51x51 OX2 receptor 5WS3 PAF receptor 5ZKP
ECL1 122 23.52x52 - - - -
TM3 123 3.21x21 μ receptor 5C1M μ receptor 5C1M
TM3 124 3.22x22 μ receptor 5C1M apelin receptor 5VBL
TM3 125 3.23x23 μ receptor 5C1M κ receptor 6B73
TM3 126 3.24x24 μ receptor 5C1M - -
TM3 127 3.25x25 μ receptor 5C1M μ receptor 5C1M
TM3 128 3.26x26 μ receptor 5C1M μ receptor 5C1M
TM3 129 3.27x27 μ receptor 5C1M 5-HT2B receptor 5TUD
TM3 130 3.28x28 μ receptor 5C1M μ receptor 5C1M
TM3 131 3.29x29 μ receptor 5C1M AT1 receptor 4ZUD
TM3 132 3.30x30 μ receptor 5C1M OX2 receptor 5WS3
TM3 133 3.31x31 μ receptor 5C1M 5-HT2B receptor 5TUD
TM3 134 3.32x32 μ receptor 5C1M S1P1 receptor 3V2Y
TM3 135 3.33x33 μ receptor 5C1M BLT1 receptor 5X33
TM3 136 3.34x34 μ receptor 5C1M M2 receptor 4MQT
TM3 137 3.35x35 μ receptor 5C1M CB1 receptor 5XRA
TM3 138 3.36x36 μ receptor 5C1M β2-adrenoceptor 3SN6
TM3 139 3.37x37 μ receptor 5C1M OX2 receptor 5WS3
TM3 140 3.38x38 μ receptor 5C1M OX2 receptor 5WS3
TM3 141 3.39x39 μ receptor 5C1M μ receptor 5C1M
TM3 142 3.40x40 μ receptor 5C1M NOP receptor 5DHG
TM3 143 3.41x41 μ receptor 5C1M LPA6 receptor 5XSZ
TM3 144 3.42x42 μ receptor 5C1M Rhodopsin 4ZWJ
TM3 145 3.43x43 μ receptor 5C1M μ receptor 5C1M
TM3 146 3.44x44 μ receptor 5C1M Rhodopsin 4ZWJ
TM3 147 3.45x45 μ receptor 5C1M 5-HT2B receptor 5TUD
TM3 148 3.46x46 μ receptor 5C1M β2-adrenoceptor 3SN6
TM3 149 3.47x47 μ receptor 5C1M β2-adrenoceptor 3SN6
TM3 150 3.48x48 μ receptor 5C1M 5-HT2C receptor 6BQG
TM3 151 3.49x49 μ receptor 5C1M Rhodopsin 4ZWJ
TM3 152 3.50x50 μ receptor 5C1M μ receptor 5C1M
TM3 153 3.51x51 μ receptor 5C1M μ receptor 5C1M
TM3 154 3.52x52 μ receptor 5C1M P2Y1 receptor 4XNW
TM3 155 3.53x53 μ receptor 5C1M μ receptor 5C1M
TM3 156 3.54x54 μ receptor 5C1M β2-adrenoceptor 3SN6
TM3 157 3.55x55 μ receptor 5C1M μ receptor 5C1M
TM3 158 3.56x56 μ receptor 5C1M CB1 receptor 5XRA
ICL2 159 34.50x50 μ receptor 5C1M μ receptor 5C1M
ICL2 160 34.51x51 μ receptor 5C1M M2 receptor 4MQT
ICL2 161 34.52x52 μ receptor 5C1M - -
ICL2 162 34.53x53 μ receptor 5C1M μ receptor 5C1M
ICL2 163 34.54x54 μ receptor 5C1M LPA6 receptor 5XSZ
ICL2 164 34.55x55 μ receptor 5C1M M2 receptor 4MQT
ICL2 165 34.56x56 μ receptor 5C1M CCR9 5LWE
ICL2 166 34.57x57 μ receptor 5C1M - -
TM4 167 4.38x38 μ receptor 5C1M μ receptor 5C1M
TM4 168 4.39x39 μ receptor 5C1M 5-HT2B receptor 5TUD
TM4 169 4.40x40 μ receptor 5C1M NTS1 receptor 5T04
TM4 170 4.41x41 μ receptor 5C1M Rhodopsin 4ZWJ
TM4 171 4.42x42 μ receptor 5C1M μ receptor 5C1M
TM4 172 4.43x43 μ receptor 5C1M 5-HT1B receptor 6G79
TM4 173 4.44x44 μ receptor 5C1M - -
TM4 174 4.45x45 μ receptor 5C1M μ receptor 5C1M
TM4 175 4.46x46 μ receptor 5C1M β2-adrenoceptor 3SN6
TM4 176 4.47x47 μ receptor 5C1M μ receptor 5C1M
TM4 177 4.48x48 μ receptor 5C1M M2 receptor 4MQT
TM4 178 4.49x49 μ receptor 5C1M Rhodopsin 4ZWJ
TM4 179 4.50x50 μ receptor 5C1M μ receptor 5C1M
TM4 180 4.51x51 μ receptor 5C1M κ receptor 6B73
TM4 181 4.52x52 μ receptor 5C1M μ receptor 5C1M
TM4 182 4.53x53 μ receptor 5C1M μ receptor 5C1M
TM4 183 4.54x54 μ receptor 5C1M β2-adrenoceptor 3SN6
TM4 184 4.55x55 μ receptor 5C1M β2-adrenoceptor 3SN6
TM4 185 4.56x56 μ receptor 5C1M M2 receptor 4MQT
TM4 186 4.57x57 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 187 4.58x59 OX2 receptor 5WS3 5-HT2C receptor 6BQG
TM4 188 4.59x60 μ receptor 5C1M β2-adrenoceptor 3SN6
TM4 189 4.60x61 μ receptor 5C1M - -
TM4 190 4.61x62 μ receptor 5C1M 5-HT2B receptor 5TUD
TM4 191 4.62x63 μ receptor 5C1M 5-HT2C receptor 6BQG
TM4 192 4.63x64 μ receptor 5C1M - -
TM4 193 4.64x65 OX2 receptor 5WS3 CCR5 5UIW
ECL2 194 μ receptor 5C1M - -
ECL2 195 μ receptor 5C1M - -
ECL2 196 μ receptor 5C1M - -
ECL2 197 μ receptor 5C1M - -
ECL2 198 μ receptor 5C1M - -
ECL2 199 μ receptor 5C1M - -
ECL2 200 μ receptor 5C1M - -
ECL2 201 μ receptor 5C1M - -
ECL2 202 μ receptor 5C1M - -
ECL2 203 μ receptor 5C1M - -
ECL2 204 - - - -
ECL2 205 45.50x50 μ receptor 5C1M μ receptor 5C1M
ECL2 206 45.51x51 μ receptor 5C1M 5-HT2B receptor 5TUD
ECL2 207 45.52x52 μ receptor 5C1M - -
ECL2 208 μ receptor 5C1M - -
ECL2 209 μ receptor 5C1M - -
ECL2 210 μ receptor 5C1M - -
ECL2 211 μ receptor 5C1M - -
ECL2 212 μ receptor 5C1M μ receptor 5C1M
TM5 213 5.33x34 μ receptor 5C1M C5a1 receptor 5O9H
TM5 214 5.34x35 μ receptor 5C1M - -
TM5 215 5.35x36 μ receptor 5C1M Y1 receptor 5ZBH
TM5 216 5.36x37 μ receptor 5C1M β2-adrenoceptor 3SN6
TM5 217 5.37x38 μ receptor 5C1M CB1 receptor 5XRA
TM5 218 5.38x39 μ receptor 5C1M - -
TM5 219 5.39x40 μ receptor 5C1M PAR1 3VW7
TM5 220 5.40x41 μ receptor 5C1M 5-HT1B receptor 6G79
TM5 221 5.41x42 μ receptor 5C1M Y1 receptor 5ZBH
TM5 222 5.42x43 μ receptor 5C1M US28 4XT1
TM5 223 5.43x44 μ receptor 5C1M Y1 receptor 5ZBH
TM5 224 5.44x45 μ receptor 5C1M 5-HT2B receptor 5TUD
TM5 225 5.45x46 μ receptor 5C1M AT2 receptor 5UNG
TM5 226 5.46x461 μ receptor 5C1M FFA1 receptor 5TZY
TM5 227 5.47x47 μ receptor 5C1M μ receptor 5C1M
TM5 228 5.48x48 μ receptor 5C1M 5-HT2B receptor 5TUD
TM5 229 5.49x49 μ receptor 5C1M κ receptor 6B73
TM5 230 5.50x50 μ receptor 5C1M μ receptor 5C1M
TM5 231 5.51x51 μ receptor 5C1M CXCR4 3ODU
TM5 232 5.52x52 μ receptor 5C1M β2-adrenoceptor 3SN6
TM5 233 5.53x53 μ receptor 5C1M Rhodopsin 5DYS
TM5 234 5.54x54 μ receptor 5C1M β2-adrenoceptor 3SN6
TM5 235 5.55x55 μ receptor 5C1M AT2 receptor 5UNG
TM5 236 5.56x56 μ receptor 5C1M μ receptor 5C1M
TM5 237 5.57x57 μ receptor 5C1M CB1 receptor 5XRA
TM5 238 5.58x58 μ receptor 5C1M μ receptor 5C1M
TM5 239 5.59x59 μ receptor 5C1M μ receptor 5C1M
TM5 240 5.60x60 μ receptor 5C1M μ receptor 5C1M
TM5 241 5.61x61 μ receptor 5C1M M2 receptor 4MQT
TM5 242 5.62x62 μ receptor 5C1M M2 receptor 4MQT
TM5 243 5.63x63 μ receptor 5C1M M2 receptor 4MQT
TM5 244 5.64x64 μ receptor 5C1M β2-adrenoceptor 3SN6
TM5 245 5.65x65 μ receptor 5C1M μ receptor 5C1M
TM5 246 5.66x66 μ receptor 5C1M P2Y12 receptor 4NTJ
TM5 247 5.67x67 μ receptor 5C1M - -
TM5 248 5.68x68 μ receptor 5C1M - -
TM5 249 5.69x69 β2-adrenoceptor 3SN6 β2-adrenoceptor 3SN6
TM5 250 5.70x70 β2-adrenoceptor 3SN6 - -
TM5 251 5.71x71 β2-adrenoceptor 3SN6 - -
TM5 252 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 253 5.73x73 β2-adrenoceptor 3SN6 - -
TM5 254 5.74x74 β2-adrenoceptor 3SN6 - -
TM5 255 5.75x75 β2-adrenoceptor 3SN6 β2-adrenoceptor 3SN6
TM5 256 5.76x76 β2-adrenoceptor 3SN6 - -
ICL3 257 - - - -
ICL3 258 - - - -
ICL3 259 - - - -
ICL3 260 - - - -
ICL3 261 - - - -
ICL3 317 - - - -
ICL3 318 - - - -
ICL3 319 - - - -
ICL3 320 - - - -
ICL3 321 - - - -
TM6 322 6.24x24 μ receptor 5C1M A1 receptor 6D9H
TM6 323 6.25x25 μ receptor 5C1M - -
TM6 324 6.26x26 μ receptor 5C1M μ receptor 5C1M
TM6 325 6.27x27 μ receptor 5C1M A2A receptor 5G53
TM6 326 6.28x28 μ receptor 5C1M β2-adrenoceptor 3SN6
TM6 327 6.29x29 μ receptor 5C1M Rhodopsin 4ZWJ
TM6 328 6.30x30 μ receptor 5C1M LPA6 receptor 5XSZ
TM6 329 6.31x31 μ receptor 5C1M Rhodopsin 4ZWJ
TM6 330 6.32x32 μ receptor 5C1M μ receptor 5C1M
TM6 331 6.33x33 μ receptor 5C1M Rhodopsin 4ZWJ
TM6 332 6.34x34 μ receptor 5C1M NTS1 receptor 5T04
TM6 333 6.35x35 μ receptor 5C1M μ receptor 5C1M
TM6 334 6.36x36 μ receptor 5C1M μ receptor 5C1M
TM6 335 6.37x37 μ receptor 5C1M β2-adrenoceptor 3SN6
TM6 336 6.38x38 μ receptor 5C1M μ receptor 5C1M
TM6 337 6.39x39 μ receptor 5C1M μ receptor 5C1M
TM6 338 6.40x40 μ receptor 5C1M β2-adrenoceptor 3SN6
TM6 339 6.41x41 μ receptor 5C1M μ receptor 5C1M
TM6 340 6.42x42 μ receptor 5C1M CB1 receptor 5XRA
TM6 341 6.43x43 μ receptor 5C1M 5-HT2B receptor 5TUD
TM6 342 6.44x44 μ receptor 5C1M μ receptor 5C1M
TM6 343 6.45x45 μ receptor 5C1M PAF receptor 5ZKP
TM6 344 6.46x46 μ receptor 5C1M β2-adrenoceptor 3SN6
TM6 345 6.47x47 μ receptor 5C1M μ receptor 5C1M
TM6 346 6.48x48 μ receptor 5C1M μ receptor 5C1M
TM6 347 6.49x49 μ receptor 5C1M β2-adrenoceptor 3SN6
TM6 348 6.50x50 μ receptor 5C1M μ receptor 5C1M
TM6 349 6.51x51 μ receptor 5C1M NOP receptor 5DHG
TM6 350 6.52x52 μ receptor 5C1M CXCR4 3ODU
TM6 351 6.53x53 μ receptor 5C1M Rhodopsin 4ZWJ
TM6 352 6.54x54 μ receptor 5C1M ETB receptor 5X93
TM6 353 6.55x55 μ receptor 5C1M β2-adrenoceptor 3SN6
TM6 354 6.56x56 μ receptor 5C1M Y1 receptor 5ZBH
TM6 355 6.57x57 μ receptor 5C1M - -
TM6 356 6.58x58 μ receptor 5C1M - -
TM6 357 6.59x59 μ receptor 5C1M μ receptor 5C1M
TM6 358 6.60x60 μ receptor 5C1M M2 receptor 4MQT
TM6 359 6.61x61 μ receptor 5C1M - -
ECL3 360 - - - -
ECL3 361 Y1 receptor 5ZBH - -
ECL3 362 Y1 receptor 5ZBH - -
ECL3 363 Y1 receptor 5ZBH - -
ECL3 364 - - - -
TM7 365 7.28x27 μ receptor 5C1M - -
TM7 366 7.29x28 μ receptor 5C1M AT2 receptor 5UNG
TM7 367 7.30x29 μ receptor 5C1M 5-HT2C receptor 6BQG
TM7 368 7.31x30 μ receptor 5C1M - -
TM7 369 7.32x31 μ receptor 5C1M FFA1 receptor 5TZY
TM7 370 7.33x32 μ receptor 5C1M 5-HT1B receptor 6G79
TM7 371 7.34x33 μ receptor 5C1M - -
TM7 372 7.35x34 μ receptor 5C1M CXCR4 3ODU
TM7 373 7.36x35 μ receptor 5C1M CXCR4 3ODU
TM7 374 7.37x36 μ receptor 5C1M μ receptor 5C1M
TM7 375 7.38x37 μ receptor 5C1M - -
TM7 376 7.39x38 μ receptor 5C1M OX2 receptor 5WS3
TM7 377 7.40x39 μ receptor 5C1M AT2 receptor 5UNG
TM7 378 7.41x40 μ receptor 5C1M μ receptor 5C1M
TM7 379 7.42x41 μ receptor 5C1M A2A receptor 5G53
TM7 380 7.43x42 μ receptor 5C1M μ receptor 5C1M
TM7 381 7.44x43 μ receptor 5C1M NTS1 receptor 5T04
TM7 382 7.45x45 μ receptor 5C1M 5-HT2B receptor 5TUD
TM7 383 7.46x46 μ receptor 5C1M Rhodopsin 4ZWJ
TM7 384 7.47x47 μ receptor 5C1M μ receptor 5C1M
TM7 385 7.48x48 μ receptor 5C1M 5-HT2B receptor 5TUD
TM7 386 7.49x49 μ receptor 5C1M μ receptor 5C1M
TM7 387 7.50x50 μ receptor 5C1M μ receptor 5C1M
TM7 388 7.51x51 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
TM7 389 7.52x52 OX2 receptor 5WS3 5-HT2B receptor 5TUD
TM7 390 7.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 391 7.54x54 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
TM7 392 7.55x55 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 393 7.56x56 OX2 receptor 5WS3 Rhodopsin 4ZWJ
H8 394 8.47x47 OX2 receptor 5WS3 - -
H8 395 8.48x48 OX2 receptor 5WS3 A2A receptor 4UHR
H8 396 8.49x49 OX2 receptor 5WS3 AT2 receptor 5UNG
H8 397 8.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 398 8.51x51 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 399 8.52x52 OX2 receptor 5WS3 AT2 receptor 5UNG
H8 400 8.53x53 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
H8 401 8.54x54 OX2 receptor 5WS3 apelin receptor 5VBL
H8 402 8.55x55 OX2 receptor 5WS3 Rhodopsin 4ZWJ
H8 403 8.56x56 OX2 receptor 5WS3 β2-adrenoceptor 3SN6
H8 404 8.57x57 OX2 receptor 5WS3 Rhodopsin 4ZWJ
H8 405 8.58x58 OX2 receptor 5WS3 μ receptor 4DKL
C-term 406 - - - -
C-term 407 - - - -
C-term 408 - - - -
C-term 409 - - - -
C-term 410 - - - -