GHRH receptor homology model

PROTEIN CLASS

Class B1 (Secretin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 4.86 docs)

VERSION

2018-07-10

MAIN TEMPLATE

GLP-1 receptor (sequence similarity: 53%) PDB: 5NX2

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 75.8 10.8 13.5
Side-chains 35.4 18.9 45.8

Number of backbone templates: 5
Number of rotamer templates: 8

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5XEZ
5EE7
4L6R
5NX2
4Z9G
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 114 glucagon receptor 5XEZ glucagon receptor 5XEZ
N-term 115 glucagon receptor 5XEZ glucagon receptor 5XEZ
N-term 116 glucagon receptor 5XEZ glucagon receptor 5XEZ
N-term 117 glucagon receptor 5XEZ glucagon receptor 5XEZ
N-term 118 glucagon receptor 5XEZ glucagon receptor 5XEZ
TM1 119 1.29x29 glucagon receptor 5XEZ - -
TM1 120 1.30x30 glucagon receptor 5XEZ - -
TM1 121 1.31x31 glucagon receptor 5XEZ glucagon receptor 5XEZ
TM1 122 1.32x32 glucagon receptor 5XEZ - -
TM1 123 1.33x33 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 124 1.34x34 GLP-1 receptor 5NX2 - -
TM1 125 1.35x35 GLP-1 receptor 5NX2 - -
TM1 126 1.36x36 GLP-1 receptor 5NX2 - -
TM1 127 1.37x37 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM1 128 1.38x38 GLP-1 receptor 5NX2 - -
TM1 129 1.39x39 GLP-1 receptor 5NX2 - -
TM1 130 1.40x40 GLP-1 receptor 5NX2 - -
TM1 131 1.41x41 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 132 1.42x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 133 1.43x43 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 134 1.44x44 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 135 1.45x45 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 136 1.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 137 1.47x47 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM1 138 1.48x48 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM1 139 1.49x49 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM1 140 1.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 141 1.51x51 GLP-1 receptor 5NX2 CT receptor 5UZ7
TM1 142 1.52x52 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM1 143 1.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 144 1.54x54 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 145 1.55x55 GLP-1 receptor 5NX2 - -
TM1 146 1.56x56 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM1 147 1.57x57 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 148 1.58x58 GLP-1 receptor 5NX2 - -
TM1 149 1.59x59 GLP-1 receptor 5NX2 - -
TM1 150 1.60x60 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 151 1.61x61 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 152 1.62x62 GLP-1 receptor 5NX2 CT receptor 5UZ7
TM1 153 1.63x63 GLP-1 receptor 5NX2 - -
TM1 154 1.64x64 GLP-1 receptor 5NX2 glucagon receptor 5EE7
ICL1 155 12.48x48 - - - -
ICL1 156 12.49x49 glucagon receptor 5EE7 - -
ICL1 157 12.50x50 glucagon receptor 5EE7 glucagon receptor 5EE7
ICL1 158 12.51x51 - - - -
TM2 159 2.44x44 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 160 2.45x45 GLP-1 receptor 5NX2 - -
TM2 161 2.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 162 2.47x47 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 163 2.48x48 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 164 2.49x49 GLP-1 receptor 5NX2 - -
TM2 165 2.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 166 2.51x51 GLP-1 receptor 5NX2 - -
TM2 167 2.52x52 GLP-1 receptor 5NX2 - -
TM2 168 2.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 169 2.54x54 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 170 2.55x55 GLP-1 receptor 5NX2 - -
TM2 171 2.56x56 GLP-1 receptor 5NX2 CT receptor 5UZ7
TM2 172 2.57x57 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 173 2.58x58 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 174 2.59x59 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 175 2.60x60 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM2 176 2.61x61 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 177 2.62x62 GLP-1 receptor 5NX2 - -
TM2 178 2.63x63 GLP-1 receptor 5NX2 glucagon receptor 5EE7
TM2 179 2.64x64 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 180 2.65x65 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 181 2.66x66 GLP-1 receptor 5NX2 - -
TM2 182 2.67x67 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 183 2.68x68 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 184 2.69x69 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 185 2.70x70 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 186 2.71x71 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL1 187 - - - -
ECL1 188 - - - -
ECL1 189 - - - -
ECL1 190 - - - -
ECL1 191 - - - -
ECL1 192 - - - -
ECL1 193 - - - -
ECL1 194 - - - -
ECL1 195 - - - -
ECL1 196 - - - -
ECL1 197 - - - -
TM3 198 3.25x25 glucagon receptor 5XEZ - -
TM3 199 3.26x26 glucagon receptor 5XEZ - -
TM3 200 3.27x27 GLP-1 receptor 5NX2 CT receptor 5UZ7
TM3 201 3.28x28 GLP-1 receptor 5NX2 - -
TM3 202 3.29x29 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 203 3.30x30 GLP-1 receptor 5NX2 CT receptor 5UZ7
TM3 204 3.31x31 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM3 205 3.32x32 GLP-1 receptor 5NX2 - -
TM3 206 3.33x33 GLP-1 receptor 5NX2 - -
TM3 207 3.34x34 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM3 208 3.35x35 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM3 209 3.36x36 GLP-1 receptor 5NX2 - -
TM3 210 3.37x37 GLP-1 receptor 5NX2 - -
TM3 211 3.38x38 GLP-1 receptor 5NX2 - -
TM3 212 3.39x39 GLP-1 receptor 5NX2 - -
TM3 213 3.40x40 GLP-1 receptor 5NX2 - -
TM3 214 3.41x41 GLP-1 receptor 5NX2 - -
TM3 215 3.42x42 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM3 216 3.43x43 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 217 3.44x44 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM3 218 3.45x45 GLP-1 receptor 5NX2 - -
TM3 219 3.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 220 3.47x47 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 221 3.48x48 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 222 3.49x49 GLP-1 receptor 5NX2 - -
TM3 223 3.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 224 3.51x51 GLP-1 receptor 5NX2 - -
TM3 225 3.52x52 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 226 3.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 227 3.54x54 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 228 3.55x55 GLP-1 receptor 5NX2 - -
TM3 229 3.56x56 GLP-1 receptor 5NX2 - -
TM3 230 3.57x57 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 231 3.58x58 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 232 3.59x59 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 233 3.60x60 GLP-1 receptor 5NX2 - -
ICL2 234 - - - -
ICL2 235 - - - -
ICL2 236 - - - -
ICL2 237 - - - -
ICL2 238 - - - -
ICL2 239 - - - -
TM4 240 4.40x41 GLP-1 receptor 5NX2 - -
TM4 241 4.41x42 GLP-1 receptor 5NX2 - -
TM4 242 4.42x43 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 243 4.43x44 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM4 244 4.44x45 GLP-1 receptor 5NX2 CT receptor 5UZ7
TM4 245 4.45x46 GLP-1 receptor 5NX2 - -
TM4 246 4.46x47 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 247 4.47x48 GLP-1 receptor 5NX2 CT receptor 5UZ7
TM4 248 4.48x49 GLP-1 receptor 5NX2 - -
TM4 249 4.49x491 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 250 4.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 251 4.51x51 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 252 4.52x52 GLP-1 receptor 5NX2 - -
TM4 253 4.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 254 4.54x54 GLP-1 receptor 5NX2 - -
TM4 255 4.55x55 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 256 4.56x56 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 257 4.57x57 GLP-1 receptor 5NX2 CT receptor 5UZ7
TM4 258 4.58x58 GLP-1 receptor 5NX2 - -
TM4 259 4.59x59 GLP-1 receptor 5NX2 - -
TM4 260 4.60x60 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 261 4.61x61 GLP-1 receptor 5NX2 - -
TM4 262 4.62x62 GLP-1 receptor 5NX2 - -
TM4 263 4.63x63 GLP-1 receptor 5NX2 - -
TM4 264 4.64x64 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 265 4.65x65 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM4 266 4.66x66 GLP-1 receptor 5NX2 - -
TM4 267 4.67x67 GLP-1 receptor 5NX2 - -
TM4 268 4.68x68 glucagon receptor 5XEZ glucagon receptor 5XEZ
ECL2 269 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL2 270 GLP-1 receptor 5NX2 - -
ECL2 271 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL2 272 45.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL2 273 45.51x51 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL2 274 45.52x52 GLP-1 receptor 5NX2 - -
ECL2 275 - - - -
ECL2 276 - - - -
ECL2 277 - - - -
ECL2 278 GLP-1 receptor 5NX2 - -
ECL2 279 GLP-1 receptor 5NX2 - -
ECL2 280 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 281 5.35x36 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 282 5.36x37 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 283 5.37x38 GLP-1 receptor 5NX2 glucagon receptor 5YQZ
TM5 284 5.38x381 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 285 5.39x39 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 286 5.40x40 GLP-1 receptor 5NX2 - -
TM5 287 5.41x41 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM5 288 5.42x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 289 5.43x43 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 290 5.44x44 GLP-1 receptor 5NX2 - -
TM5 291 5.45x45 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM5 292 5.46x46 GLP-1 receptor 5NX2 - -
TM5 293 5.47x47 GLP-1 receptor 5NX2 - -
TM5 294 5.48x48 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 295 5.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 296 5.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 297 5.51x51 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 298 5.52x52 GLP-1 receptor 5NX2 - -
TM5 299 5.53x53 GLP-1 receptor 5NX2 - -
TM5 300 5.54x54 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 301 5.55x55 GLP-1 receptor 5NX2 CT receptor 5UZ7
TM5 302 5.56x56 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM5 303 5.57x57 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM5 304 5.58x58 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 305 5.59x59 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM5 306 5.60x60 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 307 5.61x61 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM5 308 5.62x62 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 309 5.63x63 GLP-1 receptor 5NX2 - -
TM5 310 5.64x64 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 311 5.65x65 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ICL3 312 - - - -
ICL3 313 - - - -
ICL3 314 - - - -
ICL3 315 - - - -
ICL3 316 - - - -
ICL3 317 - - - -
ICL3 318 - - - -
TM6 319 6.30x30 CRF1 receptor 4Z9G - -
TM6 320 6.31x31 CRF1 receptor 4Z9G - -
TM6 321 6.32x32 CRF1 receptor 4Z9G - -
TM6 322 6.33x33 GLP-1 receptor 5NX2 - -
TM6 323 6.34x34 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM6 324 6.35x35 GLP-1 receptor 5NX2 CT receptor 5UZ7
TM6 325 6.36x36 GLP-1 receptor 5NX2 - -
TM6 326 6.37x37 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 327 6.38x38 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 328 6.39x39 GLP-1 receptor 5NX2 - -
TM6 329 6.40x40 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 330 6.41x41 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 331 6.42x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 332 6.43x43 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 333 6.44x44 GLP-1 receptor 5NX2 - -
TM6 334 6.45x45 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 335 6.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 336 6.47x47 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM6 337 6.48x48 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 338 6.49x49 GLP-1 receptor 5NX2 - -
TM6 339 6.50x50 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM6 340 6.51x51 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM6 341 6.52x52 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM6 342 6.53x53 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM6 343 6.54x54 GLP-1 receptor 5NX2 - -
TM6 344 6.55x55 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 345 6.56x56 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 346 6.57x57 GLP-1 receptor 5NX2 - -
TM6 347 6.58x58 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL3 348 - - - -
ECL3 349 - - - -
ECL3 350 - - - -
ECL3 351 - - - -
ECL3 352 - - - -
ECL3 353 - - - -
TM7 354 7.35x34 GLP-1 receptor 5NX2 - -
TM7 355 7.36x35 GLP-1 receptor 5NX2 - -
TM7 356 7.37x36 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 357 7.38x37 GLP-1 receptor 5NX2 - -
TM7 358 7.39x38 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 359 7.40x39 GLP-1 receptor 5NX2 - -
TM7 360 7.41x40 GLP-1 receptor 5NX2 - -
TM7 361 7.42x41 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 362 7.43x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 363 7.44x43 GLP-1 receptor 5NX2 - -
TM7 364 7.45x44 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM7 365 7.46x45 GLP-1 receptor 5NX2 - -
TM7 366 7.47x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 367 7.48x47 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 368 7.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 369 7.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 370 7.51x51 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM7 371 7.52x52 GLP-1 receptor 5NX2 - -
TM7 372 7.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 373 7.54x54 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 374 7.55x55 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 375 7.56x56 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 376 7.57x57 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 377 7.58x58 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 378 7.59x59 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 379 7.60x60 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
H8 380 8.47x47 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 381 8.48x48 GLP-1 receptor 5NX2 - -
H8 382 8.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 383 8.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 384 8.51x51 GLP-1 receptor 5NX2 - -
H8 385 8.52x52 GLP-1 receptor 5NX2 CT receptor 5UZ7
H8 386 8.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 387 8.54x54 GLP-1 receptor 5NX2 - -
H8 388 8.55x55 GLP-1 receptor 5NX2 - -
H8 389 8.56x56 GLP-1 receptor 5NX2 glucagon receptor 5EE7
H8 390 8.57x57 GLP-1 receptor 5NX2 - -
H8 391 8.58x58 glucagon receptor 4L6R glucagon receptor 4L6R
H8 392 8.59x59 glucagon receptor 4L6R glucagon receptor 4L6R
H8 393 8.60x60 glucagon receptor 4L6R - -
H8 394 8.61x61 glucagon receptor 4L6R - -
H8 395 8.62x62 glucagon receptor 4L6R - -
H8 396 8.63x63 glucagon receptor 4L6R - -
H8 397 8.64x64 glucagon receptor 4L6R GLP-1 receptor 6B3J
H8 398 8.65x65 glucagon receptor 4L6R - -
H8 399 8.66x66 glucagon receptor 4L6R - -
H8 400 8.67x67 glucagon receptor 4L6R - -
H8 401 8.68x68 glucagon receptor 4L6R - -
H8 402 8.69x69 glucagon receptor 4L6R CT receptor 5UZ7
H8 403 8.70x70 glucagon receptor 4L6R - -
H8 404 8.71x71 glucagon receptor 4L6R - -
H8 405 8.72x72 glucagon receptor 4L6R - -
C-term 406 - - - -
C-term 407 - - - -
C-term 408 - - - -
C-term 409 - - - -
C-term 410 - - - -