GnRH1 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 9.7 docs)

VERSION

2018-07-10

MAIN TEMPLATE

κ receptor (sequence similarity: 37%) PDB: 6B73

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 74.5 11.1 14.4
Side-chains 16.4 55.0 28.5

Number of backbone templates: 6
Number of rotamer templates: 44

NGL is a WebGL based 3D viewer powered by MMTF.

6B73
5WS3
4ZJ8
5VBL
3SN6
4UHR
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 31 - - - -
N-term 32 - - - -
N-term 33 κ receptor 6B73 κ receptor 6B73
N-term 34 κ receptor 6B73 κ receptor 6B73
N-term 35 κ receptor 6B73 κ receptor 6B73
TM1 36 1.33x33 κ receptor 6B73 S1P1 receptor 3V2Y
TM1 37 1.34x34 κ receptor 6B73 κ receptor 6B73
TM1 38 1.35x35 κ receptor 6B73 - -
TM1 39 1.36x36 κ receptor 6B73 5-HT1B receptor 6G79
TM1 40 1.37x37 κ receptor 6B73 A2A receptor 5G53
TM1 41 1.38x38 κ receptor 6B73 κ receptor 6B73
TM1 42 1.39x39 κ receptor 6B73 M3 receptor 4U15
TM1 43 1.40x40 κ receptor 6B73 Rhodopsin 5DYS
TM1 44 1.41x41 κ receptor 6B73 M3 receptor 4U15
TM1 45 1.42x42 κ receptor 6B73 NTS1 receptor 5T04
TM1 46 1.43x43 κ receptor 6B73 κ receptor 6B73
TM1 47 1.44x44 κ receptor 6B73 5-HT1B receptor 6G79
TM1 48 1.45x45 κ receptor 6B73 Rhodopsin 5DYS
TM1 49 1.46x46 κ receptor 6B73 A1 receptor 6D9H
TM1 50 1.47x47 κ receptor 6B73 CCR9 5LWE
TM1 51 1.48x48 κ receptor 6B73 apelin receptor 5VBL
TM1 52 1.49x49 κ receptor 6B73 - -
TM1 53 1.50x50 κ receptor 6B73 κ receptor 6B73
TM1 54 1.51x51 κ receptor 6B73 5-HT1B receptor 6G79
TM1 55 1.52x52 κ receptor 6B73 - -
TM1 56 1.53x53 κ receptor 6B73 - -
TM1 57 1.54x54 κ receptor 6B73 NTS1 receptor 5T04
TM1 58 1.55x55 κ receptor 6B73 5-HT2B receptor 5TUD
TM1 59 1.56x56 κ receptor 6B73 - -
TM1 60 1.57x57 κ receptor 6B73 CCR5 5UIW
TM1 61 1.58x58 κ receptor 6B73 - -
TM1 62 1.59x59 κ receptor 6B73 β2-adrenoceptor 3SN6
TM1 63 1.60x60 κ receptor 6B73 - -
ICL1 64 - - - -
ICL1 65 - - - -
ICL1 66 - - - -
ICL1 67 - - - -
ICL1 68 - - - -
ICL1 69 - - - -
ICL1 70 - - - -
ICL1 71 12.48x48 OX2 receptor 5WS3 Rhodopsin 5DYS
ICL1 72 12.49x49 OX2 receptor 5WS3 Rhodopsin 5DYS
ICL1 73 12.50x50 OX2 receptor 5WS3 5-HT1B receptor 6G79
ICL1 74 12.51x51 - - - -
TM2 75 2.38x38 κ receptor 6B73 - -
TM2 76 2.39x39 κ receptor 6B73 S1P1 receptor 3V2Y
TM2 77 2.40x40 κ receptor 6B73 PAF receptor 5ZKP
TM2 78 2.41x41 κ receptor 6B73 H1 receptor 3RZE
TM2 79 2.42x42 κ receptor 6B73 5-HT1B receptor 6G79
TM2 80 2.43x43 κ receptor 6B73 NTS1 receptor 5T04
TM2 81 2.44x44 κ receptor 6B73 P2Y12 receptor 4NTJ
TM2 82 2.45x45 κ receptor 6B73 PAR1 3VW7
TM2 83 2.46x46 κ receptor 6B73 κ receptor 6B73
TM2 84 2.47x47 κ receptor 6B73 PAF receptor 5ZKP
TM2 85 2.48x48 κ receptor 6B73 κ receptor 6B73
TM2 86 2.49x49 κ receptor 6B73 κ receptor 6B73
TM2 87 2.50x50 κ receptor 6B73 A2A receptor 5WF5
TM2 88 2.51x51 κ receptor 6B73 LPA6 receptor 5XSZ
TM2 89 2.52x52 κ receptor 6B73 κ receptor 6B73
TM2 90 2.53x53 κ receptor 6B73 - -
TM2 91 2.54x54 κ receptor 6B73 κ receptor 6B73
TM2 92 2.55x55 OX2 receptor 5WS3 LPA6 receptor 5XSZ
TM2 93 2.56x551 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM2 94 2.57x56 OX2 receptor 5WS3 5-HT1B receptor 6G79
TM2 95 2.58x57 κ receptor 6B73 κ receptor 6B73
TM2 96 2.59x58 κ receptor 6B73 κ receptor 6B73
TM2 97 2.60x59 κ receptor 6B73 LPA6 receptor 5XSZ
TM2 98 2.61x60 κ receptor 6B73 - -
TM2 99 2.62x61 κ receptor 6B73 NOP receptor 5DHG
TM2 100 2.63x62 κ receptor 6B73 5-HT1B receptor 4IAQ
TM2 101 2.64x63 κ receptor 6B73 - -
TM2 102 2.65x64 κ receptor 6B73 A1 receptor 6D9H
TM2 103 2.66x65 κ receptor 6B73 NTS1 receptor 5T04
ECL1 104 - - - -
ECL1 105 - - - -
ECL1 106 23.49x49 OX2 receptor 5WS3 CCR5 5UIW
ECL1 107 23.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL1 108 23.51x51 OX2 receptor 5WS3 CXCR4 3ODU
ECL1 109 23.52x52 - - - -
TM3 110 3.21x21 κ receptor 6B73 κ receptor 6B73
TM3 111 3.22x22 κ receptor 6B73 Y1 receptor 5ZBH
TM3 112 3.23x23 κ receptor 6B73 M3 receptor 4U15
TM3 113 3.24x24 κ receptor 6B73 κ receptor 6B73
TM3 114 3.25x25 κ receptor 6B73 κ receptor 6B73
TM3 115 3.26x26 κ receptor 6B73 κ receptor 6B73
TM3 116 3.27x27 κ receptor 6B73 AT2 receptor 5UNG
TM3 117 3.28x28 κ receptor 6B73 US28 4XT1
TM3 118 3.29x29 κ receptor 6B73 apelin receptor 5VBL
TM3 119 3.30x30 κ receptor 6B73 OX2 receptor 5WS3
TM3 120 3.31x31 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 121 3.32x32 κ receptor 6B73 - -
TM3 122 3.33x33 κ receptor 6B73 A2A receptor 5G53
TM3 123 3.34x34 κ receptor 6B73 AT1 receptor 4ZUD
TM3 124 3.35x35 κ receptor 6B73 CB1 receptor 5XRA
TM3 125 3.36x36 κ receptor 6B73 κ receptor 6B73
TM3 126 3.37x37 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 127 3.38x38 κ receptor 6B73 5-HT1B receptor 6G79
TM3 128 3.39x39 κ receptor 6B73 - -
TM3 129 3.40x40 κ receptor 6B73 NTS1 receptor 5T04
TM3 130 3.41x41 κ receptor 6B73 κ receptor 6B73
TM3 131 3.42x42 κ receptor 6B73 - -
TM3 132 3.43x43 κ receptor 6B73 PAR1 3VW7
TM3 133 3.44x44 κ receptor 6B73 Rhodopsin 5DYS
TM3 134 3.45x45 κ receptor 6B73 5-HT1B receptor 6G79
TM3 135 3.46x46 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 136 3.47x47 κ receptor 6B73 κ receptor 6B73
TM3 137 3.48x48 κ receptor 6B73 5-HT1B receptor 6G79
TM3 138 3.49x49 κ receptor 6B73 κ receptor 6B73
TM3 139 3.50x50 κ receptor 6B73 κ receptor 6B73
TM3 140 3.51x51 κ receptor 6B73 BLT1 receptor 5X33
TM3 141 3.52x52 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 142 3.53x53 κ receptor 6B73 κ receptor 6B73
TM3 143 3.54x54 κ receptor 6B73 LPA6 receptor 5XSZ
TM3 144 3.55x55 κ receptor 6B73 5-HT1B receptor 6G79
TM3 145 3.56x56 κ receptor 6B73 CB1 receptor 5XRA
ICL2 146 34.50x50 - - - -
ICL2 147 34.51x51 OX1 receptor 4ZJ8 OX1 receptor 4ZJ8
ICL2 148 34.52x52 OX1 receptor 4ZJ8 CB1 receptor 5XRA
ICL2 149 34.53x53 OX1 receptor 4ZJ8 - -
ICL2 150 OX1 receptor 4ZJ8 OX1 receptor 4ZJ8
ICL2 151 - - - -
TM4 152 4.38x38 κ receptor 6B73 Y1 receptor 5ZBH
TM4 153 4.39x39 κ receptor 6B73 NOP receptor 5DHG
TM4 154 4.40x40 κ receptor 6B73 5-HT1B receptor 6G79
TM4 155 4.41x41 κ receptor 6B73 AT1 receptor 4ZUD
TM4 156 4.42x42 κ receptor 6B73 apelin receptor 5VBL
TM4 157 4.43x43 κ receptor 6B73 NOP receptor 5DHG
TM4 158 4.44x44 κ receptor 6B73 PAF receptor 5ZKQ
TM4 159 4.45x45 κ receptor 6B73 5-HT1B receptor 6G79
TM4 160 4.46x46 κ receptor 6B73 Rhodopsin 5DYS
TM4 161 4.47x47 κ receptor 6B73 M3 receptor 4U15
TM4 162 4.48x48 κ receptor 6B73 5-HT1B receptor 6G79
TM4 163 4.49x49 κ receptor 6B73 M2 receptor 4MQT
TM4 164 4.50x50 κ receptor 6B73 κ receptor 6B73
TM4 165 4.51x51 κ receptor 6B73 μ receptor 5C1M
TM4 166 4.52x52 κ receptor 6B73 κ receptor 6B73
TM4 167 4.53x53 κ receptor 6B73 κ receptor 6B73
TM4 168 4.54x54 κ receptor 6B73 κ receptor 6B73
TM4 169 4.55x55 κ receptor 6B73 A1 receptor 6D9H
TM4 170 4.56x56 κ receptor 6B73 - -
TM4 171 4.57x57 OX2 receptor 5WS3 NTS1 receptor 5T04
TM4 172 4.58x59 OX2 receptor 5WS3 - -
TM4 173 4.59x60 κ receptor 6B73 NTS1 receptor 5T04
TM4 174 4.60x61 κ receptor 6B73 OX2 receptor 5WS3
TM4 175 4.61x62 κ receptor 6B73 NTS1 receptor 5T04
TM4 176 4.62x63 κ receptor 6B73 AT2 receptor 5UNG
TM4 177 4.63x64 κ receptor 6B73 - -
TM4 178 4.64x65 OX2 receptor 5WS3 ETB receptor 5X93
ECL2 179 - - - -
ECL2 180 - - - -
ECL2 181 - - - -
ECL2 182 - - - -
ECL2 183 - - - -
ECL2 184 - - - -
ECL2 185 - - - -
ECL2 186 - - - -
ECL2 187 - - - -
ECL2 188 - - - -
ECL2 189 - - - -
ECL2 190 - - - -
ECL2 191 - - - -
ECL2 192 - - - -
ECL2 193 - - - -
ECL2 194 - - - -
ECL2 195 - - - -
ECL2 196 - - - -
ECL2 197 - - - -
ECL2 198 - - - -
ECL2 199 - - - -
ECL2 200 45.50x50 κ receptor 6B73 κ receptor 6B73
ECL2 201 45.51x51 κ receptor 6B73 κ receptor 6B73
ECL2 202 45.52x52 κ receptor 6B73 β2-adrenoceptor 4LDE
TM5 203 5.30x31 apelin receptor 5VBL apelin receptor 5VBL
TM5 204 5.31x32 apelin receptor 5VBL NOP receptor 5DHG
TM5 205 5.32x33 apelin receptor 5VBL apelin receptor 5VBL
TM5 206 5.33x34 κ receptor 6B73 κ receptor 6B73
TM5 207 5.34x35 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 208 5.35x36 κ receptor 6B73 - -
TM5 209 5.36x37 κ receptor 6B73 M2 receptor 4MQT
TM5 210 5.37x38 κ receptor 6B73 κ receptor 6B73
TM5 211 5.38x39 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 212 5.39x40 κ receptor 6B73 US28 4XT1
TM5 213 5.40x41 κ receptor 6B73 M2 receptor 4MQT
TM5 214 5.41x42 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 215 5.42x43 κ receptor 6B73 M2 receptor 4MQT
TM5 216 5.43x44 κ receptor 6B73 κ receptor 6B73
TM5 217 5.44x45 κ receptor 6B73 ETB receptor 5X93
TM5 218 5.45x46 κ receptor 6B73 D4 receptor 5WIV
TM5 219 5.46x461 κ receptor 6B73 FFA1 receptor 5TZY
TM5 220 5.47x47 κ receptor 6B73 κ receptor 6B73
TM5 221 5.48x48 κ receptor 6B73 μ receptor 5C1M
TM5 222 5.49x49 κ receptor 6B73 κ receptor 6B73
TM5 223 5.50x50 κ receptor 6B73 κ receptor 6B73
TM5 224 5.51x51 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 225 5.52x52 κ receptor 6B73 PAR2 5NDD
TM5 226 5.53x53 κ receptor 6B73 κ receptor 6B73
TM5 227 5.54x54 κ receptor 6B73 β2-adrenoceptor 3SN6
TM5 228 5.55x55 κ receptor 6B73 PAF receptor 5ZKP
TM5 229 5.56x56 κ receptor 6B73 NTS1 receptor 5T04
TM5 230 5.57x57 κ receptor 6B73 κ receptor 6B73
TM5 231 5.58x58 κ receptor 6B73 NTS1 receptor 5T04
TM5 232 5.59x59 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 233 5.60x60 κ receptor 6B73 Y1 receptor 5ZBH
TM5 234 5.61x61 κ receptor 6B73 5-HT1B receptor 6G79
TM5 235 5.62x62 κ receptor 6B73 κ receptor 6B73
TM5 236 5.63x63 κ receptor 6B73 Rhodopsin 5DYS
TM5 237 5.64x64 κ receptor 6B73 LPA6 receptor 5XSZ
TM5 238 5.65x65 κ receptor 6B73 κ receptor 6B73
TM5 239 5.66x66 κ receptor 6B73 NTS1 receptor 5T04
TM5 240 5.67x67 κ receptor 6B73 5-HT2C receptor 6BQG
TM5 241 5.68x68 β2-adrenoceptor 3SN6 κ receptor 4DJH
TM5 242 5.69x69 β2-adrenoceptor 3SN6 β2-adrenoceptor 3SN6
TM5 243 5.70x70 β2-adrenoceptor 3SN6 NTS1 receptor 4BUO
TM5 244 5.71x71 β2-adrenoceptor 3SN6 Rhodopsin 5DYS
TM5 245 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 246 5.73x73 β2-adrenoceptor 3SN6 - -
TM5 247 5.74x74 β2-adrenoceptor 3SN6 - -
ICL3 248 κ receptor 6B73 - -
ICL3 249 - - - -
ICL3 250 - - - -
ICL3 251 - - - -
ICL3 252 - - - -
TM6 253 6.21x21 A2A receptor 4UHR - -
TM6 254 6.22x22 A2A receptor 4UHR - -
TM6 255 6.23x23 κ receptor 6B73 - -
TM6 256 6.24x24 κ receptor 6B73 - -
TM6 257 6.25x25 κ receptor 6B73 - -
TM6 258 6.26x26 κ receptor 6B73 - -
TM6 259 6.27x27 κ receptor 6B73 - -
TM6 260 6.28x28 κ receptor 6B73 μ receptor 6DDF
TM6 261 6.29x29 κ receptor 6B73 NTS1 receptor 5T04
TM6 262 6.30x30 κ receptor 6B73 AT2 receptor 5UNG
TM6 263 6.31x31 κ receptor 6B73 A1 receptor 6D9H
TM6 264 6.32x32 κ receptor 6B73 LPA6 receptor 5XSZ
TM6 265 6.33x33 κ receptor 6B73 OX2 receptor 5WS3
TM6 266 6.34x34 κ receptor 6B73 LPA6 receptor 5XSZ
TM6 267 6.35x35 κ receptor 6B73 5-HT1B receptor 6G79
TM6 268 6.36x36 κ receptor 6B73 μ receptor 5C1M
TM6 269 6.37x37 κ receptor 6B73 CCR9 5LWE
TM6 270 6.38x38 κ receptor 6B73 CB1 receptor 5XRA
TM6 271 6.39x39 κ receptor 6B73 NTS1 receptor 5T04
TM6 272 6.40x40 κ receptor 6B73 - -
TM6 273 6.41x41 κ receptor 6B73 D2 receptor 6CM4
TM6 274 6.42x42 κ receptor 6B73 CCR9 5LWE
TM6 275 6.43x43 κ receptor 6B73 C5a1 receptor 5O9H
TM6 276 6.44x44 κ receptor 6B73 κ receptor 6B73
TM6 277 6.45x45 κ receptor 6B73 β2-adrenoceptor 3SN6
TM6 278 6.46x46 κ receptor 6B73 κ receptor 6B73
TM6 279 6.47x47 κ receptor 6B73 κ receptor 6B73
TM6 280 6.48x48 κ receptor 6B73 κ receptor 6B73
TM6 281 6.49x49 κ receptor 6B73 κ receptor 6B73
TM6 282 6.50x50 κ receptor 6B73 κ receptor 6B73
TM6 283 6.51x51 κ receptor 6B73 LPA6 receptor 5XSZ
TM6 284 6.52x52 κ receptor 6B73 CXCR4 3ODU
TM6 285 6.53x53 κ receptor 6B73 LPA6 receptor 5XSZ
TM6 286 6.54x54 κ receptor 6B73 AT2 receptor 5UNG
TM6 287 6.55x55 κ receptor 6B73 C5a1 receptor 5O9H
TM6 288 6.56x56 κ receptor 6B73 μ receptor 5C1M
TM6 289 6.57x57 κ receptor 6B73 - -
TM6 290 6.58x58 κ receptor 6B73 LPA6 receptor 5XSZ
TM6 291 6.59x59 κ receptor 6B73 - -
TM6 292 6.60x60 κ receptor 6B73 M2 receptor 4MQT
TM6 293 6.61x61 κ receptor 6B73 - -
ECL3 294 - - - -
ECL3 295 κ receptor 6B73 - -
ECL3 296 κ receptor 6B73 - -
ECL3 297 κ receptor 6B73 - -
TM7 298 7.28x27 κ receptor 6B73 CB1 receptor 5XRA
TM7 299 7.29x28 κ receptor 6B73 US28 4XT1
TM7 300 7.30x29 κ receptor 6B73 5-HT2C receptor 6BQG
TM7 301 7.31x30 κ receptor 6B73 - -
TM7 302 7.32x31 κ receptor 6B73 AT2 receptor 5UNG
TM7 303 7.33x32 κ receptor 6B73 - -
TM7 304 7.34x33 κ receptor 6B73 β2-adrenoceptor 3SN6
TM7 305 7.35x34 κ receptor 6B73 - -
TM7 306 7.36x35 κ receptor 6B73 μ receptor 5C1M
TM7 307 7.37x36 κ receptor 6B73 κ receptor 6B73
TM7 308 7.38x37 κ receptor 6B73 5-HT1B receptor 6G79
TM7 309 7.39x38 κ receptor 6B73 - -
TM7 310 7.40x39 κ receptor 6B73 AT2 receptor 5UNG
TM7 311 7.41x40 κ receptor 6B73 Rhodopsin 5DYS
TM7 312 7.42x41 κ receptor 6B73 LPA6 receptor 5XSZ
TM7 313 7.43x42 κ receptor 6B73 AT2 receptor 5UNG
TM7 314 7.44x43 κ receptor 6B73 CB1 receptor 5XRA
TM7 315 7.45x45 κ receptor 6B73 κ receptor 6B73
TM7 316 7.46x46 κ receptor 6B73 - -
TM7 317 7.47x47 κ receptor 6B73 μ receptor 5C1M
TM7 318 7.48x48 κ receptor 6B73 LPA6 receptor 5XSZ
TM7 319 7.49x49 κ receptor 6B73 LPA6 receptor 5XSZ
TM7 320 7.50x50 κ receptor 6B73 κ receptor 6B73
TM7 321 7.51x51 κ receptor 6B73 β2-adrenoceptor 3SN6
TM7 322 7.52x52 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 323 7.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 324 7.54x54 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM7 325 7.55x55 OX2 receptor 5WS3 A2A receptor 5G53
TM7 326 7.56x56 OX2 receptor 5WS3 5-HT2C receptor 6BQG
C-term 327 - - - -
C-term 328 - - - -