GPR119 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 9.13 docs)

VERSION

2018-07-10

MAIN TEMPLATE

A1 receptor (sequence similarity: 40%) PDB: 6D9H

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 78.7 11.7 9.7
Side-chains 21.0 52.7 26.3

Number of backbone templates: 9
Number of rotamer templates: 41

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6D9H
5UEN
5VBL
4Z35
4PXZ
5CXV
6BQH
3SN6
4UHR
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
TM1 1 1.29x29 A1 receptor 6D9H μ receptor 5C1M
TM1 2 1.30x30 A1 receptor 6D9H - -
TM1 3 1.31x31 A1 receptor 6D9H NTS1 receptor 5T04
TM1 4 1.32x32 A1 receptor 6D9H LPA1 receptor 4Z35
TM1 5 1.33x33 A1 receptor 6D9H Y1 receptor 5ZBH
TM1 6 1.34x34 A1 receptor 6D9H - -
TM1 7 1.35x35 A1 receptor 6D9H PAF receptor 5ZKP
TM1 8 1.36x36 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM1 9 1.37x37 A1 receptor 6D9H CB1 receptor 5XRA
TM1 10 1.38x38 A1 receptor 6D9H A1 receptor 6D9H
TM1 11 1.39x39 A1 receptor 6D9H 5-HT2B receptor 5TUD
TM1 12 1.40x40 A1 receptor 6D9H 5-HT1B receptor 6G79
TM1 13 1.41x41 A1 receptor 6D9H κ receptor 6B73
TM1 14 1.42x42 A1 receptor 6D9H M2 receptor 4MQT
TM1 15 1.43x43 A1 receptor 6D9H A1 receptor 6D9H
TM1 16 1.44x44 A1 receptor 6D9H - -
TM1 17 1.45x45 A1 receptor 6D9H A2A receptor 5G53
TM1 18 1.46x46 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM1 19 1.47x47 A1 receptor 6D9H M2 receptor 4MQT
TM1 20 1.48x48 A1 receptor 6D9H D4 receptor 5WIV
TM1 21 1.49x49 A1 receptor 6D9H LPA6 receptor 5XSZ
TM1 22 1.50x50 A1 receptor 6D9H A1 receptor 6D9H
TM1 23 1.51x51 A1 receptor 6D9H 5-HT2B receptor 5TUD
TM1 24 1.52x52 A1 receptor 6D9H A1 receptor 6D9H
TM1 25 1.53x53 A1 receptor 6D9H A1 receptor 6D9H
TM1 26 1.54x54 A1 receptor 6D9H - -
TM1 27 1.55x55 A1 receptor 6D9H M2 receptor 4MQT
TM1 28 1.56x56 A1 receptor 6D9H A1 receptor 6D9H
TM1 29 1.57x57 A1 receptor 6D9H A1 receptor 6D9H
TM1 30 1.58x58 A1 receptor 6D9H CB1 receptor 5XRA
TM1 31 1.59x59 A1 receptor 6D9H 5-HT2B receptor 5TUD
TM1 32 1.60x60 A1 receptor 6D9H PAF receptor 5ZKQ
ICL1 33 - - - -
ICL1 34 apelin receptor 5VBL - -
ICL1 35 apelin receptor 5VBL - -
ICL1 36 apelin receptor 5VBL - -
ICL1 37 - - - -
TM2 38 2.37x37 A1 receptor 6D9H - -
TM2 39 2.38x38 A1 receptor 6D9H M2 receptor 4MQT
TM2 40 2.39x39 A1 receptor 6D9H AT2 receptor 5UNG
TM2 41 2.40x40 A1 receptor 6D9H - -
TM2 42 2.41x41 A1 receptor 6D9H A1 receptor 6D9H
TM2 43 2.42x42 A1 receptor 6D9H A1 receptor 6D9H
TM2 44 2.43x43 A1 receptor 6D9H - -
TM2 45 2.44x44 A1 receptor 6D9H Rhodopsin 4ZWJ
TM2 46 2.45x45 A1 receptor 6D9H μ receptor 5C1M
TM2 47 2.46x46 A1 receptor 6D9H A1 receptor 6D9H
TM2 48 2.47x47 A1 receptor 6D9H A1 receptor 6D9H
TM2 49 2.48x48 A1 receptor 6D9H A1 receptor 6D9H
TM2 50 2.49x49 A1 receptor 6D9H A1 receptor 6D9H
TM2 51 2.50x50 A1 receptor 6D9H A1 receptor 6D9H
TM2 52 2.51x51 A1 receptor 6D9H NOP receptor 5DHG
TM2 53 2.52x52 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM2 54 2.53x53 A1 receptor 6D9H M2 receptor 4MQT
TM2 55 2.54x54 A1 receptor 6D9H A1 receptor 6D9H
TM2 56 2.55x55 LPA1 receptor 4Z35 M2 receptor 4MQT
TM2 57 2.56x56 LPA1 receptor 4Z35 LPA1 receptor 4Z35
TM2 58 2.57x57 A1 receptor 6D9H A1 receptor 6D9H
TM2 59 2.58x58 A1 receptor 6D9H - -
TM2 60 2.59x59 A1 receptor 6D9H - -
TM2 61 2.60x60 A1 receptor 6D9H LPA1 receptor 4Z35
TM2 62 2.61x61 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM2 63 2.62x62 A1 receptor 6D9H A2A receptor 5G53
TM2 64 2.63x63 A1 receptor 6D9H CB1 receptor 5XRA
TM2 65 2.64x64 A1 receptor 6D9H - -
TM2 66 2.65x65 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM2 67 2.66x66 A1 receptor 6D9H PAR1 3VW7
ECL1 68 A1 receptor 6D9H A1 receptor 6D9H
ECL1 69 A1 receptor 6D9H A1 receptor 6D9H
ECL1 70 A1 receptor 6D9H A1 receptor 6D9H
TM3 71 3.18x18 P2Y12 receptor 4PXZ - -
TM3 72 3.19x19 P2Y12 receptor 4PXZ P2Y12 receptor 4PXZ
TM3 73 3.20x20 P2Y12 receptor 4PXZ - -
TM3 74 3.21x21 A1 receptor 6D9H - -
TM3 75 3.22x22 A1 receptor 6D9H PAF receptor 5ZKP
TM3 76 3.23x23 A1 receptor 6D9H Rhodopsin 4ZWJ
TM3 77 3.24x24 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM3 78 3.25x25 A1 receptor 6D9H A1 receptor 6D9H
TM3 79 3.26x26 A1 receptor 6D9H C5a1 receptor 5O9H
TM3 80 3.27x27 A1 receptor 6D9H M2 receptor 4MQT
TM3 81 3.28x28 A1 receptor 6D9H LPA1 receptor 4Z35
TM3 82 3.29x29 A1 receptor 6D9H D4 receptor 5WIV
TM3 83 3.30x30 A1 receptor 6D9H M2 receptor 4MQT
TM3 84 3.31x31 A1 receptor 6D9H A2A receptor 5G53
TM3 85 3.32x32 A1 receptor 6D9H A1 receptor 6D9H
TM3 86 3.33x33 A1 receptor 6D9H CB1 receptor 5XRA
TM3 87 3.34x34 A1 receptor 6D9H - -
TM3 88 3.35x35 A1 receptor 6D9H CB1 receptor 5XRA
TM3 89 3.36x36 A1 receptor 6D9H A1 receptor 5N2S
TM3 90 3.37x37 A1 receptor 6D9H A2A receptor 4UHR
TM3 91 3.38x38 A1 receptor 6D9H M2 receptor 4MQT
TM3 92 3.39x39 A1 receptor 6D9H A1 receptor 6D9H
TM3 93 3.40x40 A1 receptor 6D9H M2 receptor 4MQT
TM3 94 3.41x41 A1 receptor 6D9H A1 receptor 6D9H
TM3 95 3.42x42 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM3 96 3.43x43 A1 receptor 6D9H NTS1 receptor 5T04
TM3 97 3.44x44 A1 receptor 6D9H CCR9 5LWE
TM3 98 3.45x45 A1 receptor 6D9H CB1 receptor 5XRA
TM3 99 3.46x46 A1 receptor 6D9H A1 receptor 6D9H
TM3 100 3.47x47 A1 receptor 6D9H PAF receptor 5ZKP
TM3 101 3.48x48 A1 receptor 6D9H M2 receptor 4MQT
TM3 102 3.49x49 A1 receptor 6D9H A1 receptor 6D9H
TM3 103 3.50x50 A1 receptor 6D9H A1 receptor 6D9H
TM3 104 3.51x51 A1 receptor 6D9H A1 receptor 6D9H
TM3 105 3.52x52 A1 receptor 6D9H A1 receptor 6D9H
TM3 106 3.53x53 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM3 107 3.54x54 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM3 108 3.55x55 A1 receptor 6D9H A1 receptor 6D9H
TM3 109 3.56x56 A1 receptor 6D9H H1 receptor 3RZE
ICL2 110 34.50x50 - - - -
ICL2 111 34.51x51 M1 receptor 5CXV β2-adrenoceptor 3SN6
ICL2 112 34.52x52 M1 receptor 5CXV A1 receptor 6D9H
ICL2 113 34.53x53 M1 receptor 5CXV M1 receptor 5CXV
ICL2 114 34.54x54 M1 receptor 5CXV μ receptor 5C1M
ICL2 115 34.55x55 M1 receptor 5CXV BLT1 receptor 5X33
ICL2 116 34.56x56 M1 receptor 5CXV CB1 receptor 5XRA
ICL2 117 34.57x57 - - - -
TM4 118 4.38x38 A1 receptor 6D9H NTS1 receptor 5T04
TM4 119 4.39x39 A1 receptor 6D9H A2A receptor 5G53
TM4 120 4.40x40 A1 receptor 6D9H S1P1 receptor 3V2Y
TM4 121 4.41x41 A1 receptor 6D9H AT1 receptor 4ZUD
TM4 122 4.42x42 A1 receptor 6D9H A1 receptor 6D9H
TM4 123 4.43x43 A1 receptor 6D9H M2 receptor 4MQT
TM4 124 4.44x44 A1 receptor 6D9H H1 receptor 3RZE
TM4 125 4.45x45 A1 receptor 6D9H - -
TM4 126 4.46x46 A1 receptor 6D9H A1 receptor 6D9H
TM4 127 4.47x47 A1 receptor 6D9H A1 receptor 6D9H
TM4 128 4.48x48 A1 receptor 6D9H A1 receptor 6D9H
TM4 129 4.49x49 A1 receptor 6D9H apelin receptor 5VBL
TM4 130 4.50x50 A1 receptor 6D9H A1 receptor 6D9H
TM4 131 4.51x51 A1 receptor 6D9H 5-HT2B receptor 5TUD
TM4 132 4.52x52 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM4 133 4.53x53 A1 receptor 6D9H A1 receptor 6D9H
TM4 134 4.54x54 A1 receptor 6D9H - -
TM4 135 4.55x55 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM4 136 4.56x56 A1 receptor 6D9H 5-HT2B receptor 5TUD
TM4 137 4.57x57 A1 receptor 6D9H A1 receptor 6D9H
TM4 138 4.58x58 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM4 139 4.59x59 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM4 140 4.60x60 A1 receptor 6D9H A1 receptor 6D9H
TM4 141 4.61x61 A1 receptor 6D9H CB1 receptor 5XRA
TM4 142 4.62x62 A1 receptor 6D9H FFA1 receptor 5TZY
TM4 143 4.63x63 A1 receptor 6D9H 5-HT2B receptor 5TUD
TM4 144 4.64x64 M1 receptor 5CXV - -
TM4 145 4.65x65 M1 receptor 5CXV - -
TM4 146 4.66x66 M1 receptor 5CXV M2 receptor 4MQT
TM4 147 4.67x67 M1 receptor 5CXV - -
TM4 148 4.68x68 M1 receptor 5CXV - -
TM4 149 4.69x69 M1 receptor 5CXV - -
ECL2 150 - - - -
ECL2 151 - - - -
ECL2 152 - - - -
ECL2 153 - - - -
ECL2 154 - - - -
ECL2 155 45.50x50 A1 receptor 6D9H A1 receptor 6D9H
ECL2 156 45.51x51 A1 receptor 6D9H κ receptor 6B73
ECL2 157 45.52x52 A1 receptor 6D9H A1 receptor 6D9H
ECL2 158 - - - -
ECL2 159 - - - -
ECL2 160 - - - -
TM5 161 5.35x36 A1 receptor 6D9H 5-HT2B receptor 5TUD
TM5 162 5.36x37 A1 receptor 6D9H - -
TM5 163 5.37x38 A1 receptor 6D9H FFA1 receptor 5TZY
TM5 164 5.38x39 A1 receptor 6D9H BLT1 receptor 5X33
TM5 165 5.39x40 A1 receptor 6D9H PAR2 5NDD
TM5 166 5.40x41 5-HT2C receptor 6BQH A1 receptor 6D9H
TM5 167 5.41x42 5-HT2C receptor 6BQH Y1 receptor 5ZBH
TM5 168 5.42x43 A1 receptor 6D9H M2 receptor 4MQT
TM5 169 5.43x44 A1 receptor 6D9H C5a1 receptor 5O9H
TM5 170 5.44x45 A1 receptor 6D9H ETB receptor 5X93
TM5 171 5.45x46 A1 receptor 6D9H D4 receptor 5WIV
TM5 172 5.46x461 A1 receptor 6D9H PAR2 5NDD
TM5 173 5.47x47 A1 receptor 6D9H - -
TM5 174 5.48x48 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM5 175 5.49x49 A1 receptor 6D9H 5-HT1B receptor 6G79
TM5 176 5.50x50 A1 receptor 6D9H A1 receptor 6D9H
TM5 177 5.51x51 A1 receptor 6D9H PAR2 5NDD
TM5 178 5.52x52 A1 receptor 6D9H - -
TM5 179 5.53x53 A1 receptor 6D9H A1 receptor 6D9H
TM5 180 5.54x54 A1 receptor 6D9H 5-HT1B receptor 6G79
TM5 181 5.55x55 A1 receptor 6D9H Rhodopsin 4ZWJ
TM5 182 5.56x56 A1 receptor 6D9H M2 receptor 4MQT
TM5 183 5.57x57 A1 receptor 6D9H H1 receptor 3RZE
TM5 184 5.58x58 A1 receptor 6D9H FFA1 receptor 5TZY
TM5 185 5.59x59 A1 receptor 6D9H US28 4XT1
TM5 186 5.60x60 A1 receptor 6D9H - -
TM5 187 5.61x61 A1 receptor 6D9H - -
TM5 188 5.62x62 A1 receptor 6D9H - -
TM5 189 5.63x63 A1 receptor 6D9H A2A receptor 5G53
TM5 190 5.64x64 A1 receptor 6D9H CB1 receptor 5XRA
TM5 191 5.65x65 A1 receptor 6D9H A1 receptor 6D9H
TM5 192 5.66x66 A1 receptor 6D9H US28 4XT1
TM5 193 5.67x67 A1 receptor 6D9H 5-HT1B receptor 6G79
TM5 194 5.68x68 A1 receptor 6D9H NTS1 receptor 5T04
TM5 195 5.69x69 A1 receptor 6D9H - -
TM5 196 5.70x70 A1 receptor 6D9H - -
TM5 197 5.71x71 A1 receptor 6D9H Rhodopsin 4ZWJ
TM5 198 5.72x72 β2-adrenoceptor 3SN6 Rhodopsin 6CMO
TM5 199 5.73x73 β2-adrenoceptor 3SN6 - -
TM5 200 5.74x74 β2-adrenoceptor 3SN6 - -
ICL3 201 - - - -
ICL3 202 - - - -
ICL3 203 - - - -
ICL3 204 - - - -
ICL3 205 - - - -
ICL3 206 - - - -
ICL3 207 - - - -
ICL3 208 - - - -
ICL3 209 - - - -
ICL3 210 - - - -
TM6 211 6.21x21 A2A receptor 4UHR - -
TM6 212 6.22x22 A2A receptor 4UHR - -
TM6 213 6.23x23 A2A receptor 4UHR - -
TM6 214 6.24x24 A1 receptor 6D9H - -
TM6 215 6.25x25 A1 receptor 6D9H - -
TM6 216 6.26x26 A1 receptor 6D9H NTS1 receptor 5T04
TM6 217 6.27x27 A1 receptor 6D9H FFA1 receptor 5TZY
TM6 218 6.28x28 A1 receptor 6D9H - -
TM6 219 6.29x29 A1 receptor 6D9H δ receptor 4N6H
TM6 220 6.30x30 A1 receptor 6D9H CB1 receptor 5XRA
TM6 221 6.31x31 A1 receptor 6D9H - -
TM6 222 6.32x32 A1 receptor 6D9H A1 receptor 6D9H
TM6 223 6.33x33 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM6 224 6.34x34 A1 receptor 6D9H β2-adrenoceptor 4LDE
TM6 225 6.35x35 A1 receptor 6D9H M2 receptor 4MQT
TM6 226 6.36x36 A1 receptor 6D9H M2 receptor 4MQT
TM6 227 6.37x37 A1 receptor 6D9H μ receptor 5C1M
TM6 228 6.38x38 A1 receptor 6D9H M1 receptor 5CXV
TM6 229 6.39x39 A1 receptor 6D9H μ receptor 5C1M
TM6 230 6.40x40 A1 receptor 6D9H apelin receptor 5VBL
TM6 231 6.41x41 A1 receptor 6D9H BLT1 receptor 5X33
TM6 232 6.42x42 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM6 233 6.43x43 A1 receptor 6D9H C5a1 receptor 5O9H
TM6 234 6.44x44 A1 receptor 6D9H A1 receptor 6D9H
TM6 235 6.45x45 A1 receptor 6D9H A1 receptor 6D9H
TM6 236 6.46x46 A1 receptor 6D9H A1 receptor 6D9H
TM6 237 6.47x47 A1 receptor 6D9H A1 receptor 6D9H
TM6 238 6.48x48 A1 receptor 6D9H A1 receptor 6D9H
TM6 239 6.49x49 A1 receptor 6D9H μ receptor 5C1M
TM6 240 6.50x50 A1 receptor 6D9H A1 receptor 6D9H
TM6 241 6.51x51 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM6 242 6.52x52 A1 receptor 6D9H CB1 receptor 5XRA
TM6 243 6.53x53 A1 receptor 6D9H A1 receptor 6D9H
TM6 244 6.54x54 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM6 245 6.55x55 A1 receptor 6D9H C5a1 receptor 5O9H
TM6 246 6.56x56 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM6 247 6.57x57 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM6 248 6.58x58 A1 receptor 6D9H D4 receptor 5WIV
TM6 249 6.59x59 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM6 250 6.60x60 A1 receptor 6D9H - -
TM6 251 6.61x61 A1 receptor 6D9H A1 receptor 6D9H
ECL3 252 - - - -
ECL3 253 A1 receptor 5UEN - -
ECL3 254 A1 receptor 5UEN A1 receptor 5UEN
ECL3 255 A1 receptor 5UEN A1 receptor 5UEN
ECL3 256 - - - -
TM7 257 7.31x30 5-HT2C receptor 6BQH NTS1 receptor 5T04
TM7 258 7.32x31 A1 receptor 6D9H A2A receptor 5G53
TM7 259 7.33x32 A1 receptor 6D9H μ receptor 5C1M
TM7 260 7.34x33 A1 receptor 6D9H A1 receptor 6D9H
TM7 261 7.35x34 A1 receptor 6D9H LPA1 receptor 4Z35
TM7 262 7.36x35 A1 receptor 6D9H NOP receptor 5DHG
TM7 263 7.37x36 A1 receptor 6D9H S1P1 receptor 3V2Y
TM7 264 7.38x37 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM7 265 7.39x38 A1 receptor 6D9H - -
TM7 266 7.40x39 A1 receptor 6D9H AT2 receptor 5UNG
TM7 267 7.41x40 A1 receptor 6D9H A1 receptor 6D9H
TM7 268 7.42x41 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM7 269 7.43x42 A1 receptor 6D9H LPA6 receptor 5XSZ
TM7 270 7.44x43 A1 receptor 6D9H A1 receptor 6D9H
TM7 271 7.45x45 A1 receptor 6D9H A1 receptor 6D9H
TM7 272 7.46x46 A1 receptor 6D9H A1 receptor 6D9H
TM7 273 7.47x47 A1 receptor 6D9H 5-HT1B receptor 6G79
TM7 274 7.48x48 A1 receptor 6D9H μ receptor 5C1M
TM7 275 7.49x49 A1 receptor 6D9H A1 receptor 6D9H
TM7 276 7.50x50 A1 receptor 6D9H A1 receptor 6D9H
TM7 277 7.51x51 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM7 278 7.52x52 A1 receptor 6D9H β2-adrenoceptor 3SN6
TM7 279 7.53x53 A1 receptor 6D9H A1 receptor 6D9H
TM7 280 7.54x54 A1 receptor 6D9H A1 receptor 6D9H
TM7 281 7.55x55 A1 receptor 6D9H A2A receptor 5G53
TM7 282 7.56x56 A1 receptor 6D9H - -
H8 283 8.47x47 A1 receptor 6D9H - -
H8 284 8.48x48 A1 receptor 6D9H 5-HT2C receptor 6BQG
H8 285 8.49x49 A1 receptor 6D9H A2A receptor 4UHR
H8 286 8.50x50 A1 receptor 6D9H - -
H8 287 8.51x51 A1 receptor 6D9H A1 receptor 6D9H
H8 288 8.52x52 A1 receptor 6D9H - -
H8 289 8.53x53 A1 receptor 6D9H OX1 receptor 4ZJ8
H8 290 8.54x54 A1 receptor 6D9H AT2 receptor 5UNG
H8 291 8.55x55 A1 receptor 6D9H - -
H8 292 8.56x56 A1 receptor 6D9H M2 receptor 4MQT
H8 293 8.57x57 5-HT2C receptor 6BQH CB1 receptor 5XRA
H8 294 8.58x58 5-HT2C receptor 6BQH - -
H8 295 8.59x59 5-HT2C receptor 6BQH M1 receptor 5CXV
C-term 296 - - - -
C-term 297 - - - -
C-term 298 - - - -
C-term 299 - - - -
C-term 300 - - - -