GPR139 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 7.16 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 37%) PDB: 6DDE

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 75.9 14.0 10.1
Side-chains 14.3 57.7 28.0

Number of backbone templates: 7
Number of rotamer templates: 42

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6DDE
5C1M
5VBL
6BQH
4PXZ
5UNG
4N6H
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 22 - - - -
N-term 23 - - - -
N-term 24 - - - -
N-term 25 μ receptor 6DDE μ receptor 6DDE
N-term 26 μ receptor 6DDE μ receptor 6DDE
TM1 27 1.33x33 μ receptor 6DDE Y1 receptor 5ZBH
TM1 28 1.34x34 μ receptor 6DDE A2A receptor 4UHR
TM1 29 1.35x35 μ receptor 6DDE - -
TM1 30 1.36x36 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 31 1.37x37 μ receptor 6DDE D4 receptor 5WIV
TM1 32 1.38x38 μ receptor 6DDE Rhodopsin 5DYS
TM1 33 1.39x39 μ receptor 6DDE μ receptor 6DDE
TM1 34 1.40x40 μ receptor 6DDE μ receptor 6DDE
TM1 35 1.41x41 μ receptor 6DDE 5-HT2B receptor 4IB4
TM1 36 1.42x42 μ receptor 6DDE NTS1 receptor 4XES
TM1 37 1.43x43 μ receptor 6DDE - -
TM1 38 1.44x44 μ receptor 6DDE S1P1 receptor 3V2Y
TM1 39 1.45x45 μ receptor 6DDE A2A receptor 4UHR
TM1 40 1.46x46 μ receptor 6DDE μ receptor 6DDE
TM1 41 1.47x47 μ receptor 6DDE PAR2 5NDD
TM1 42 1.48x48 μ receptor 6DDE PAR2 5NDD
TM1 43 1.49x49 μ receptor 6DDE PAF receptor 5ZKQ
TM1 44 1.50x50 μ receptor 6DDE μ receptor 6DDE
TM1 45 1.51x51 μ receptor 6DDE PAR1 3VW7
TM1 46 1.52x52 μ receptor 6DDE μ receptor 6DDE
TM1 47 1.53x53 μ receptor 6DDE NTS1 receptor 4XES
TM1 48 1.54x54 μ receptor 6DDE CCR2 5T1A
TM1 49 1.55x55 μ receptor 6DDE Y1 receptor 5ZBH
TM1 50 1.56x56 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 51 1.57x57 μ receptor 6DDE NTS1 receptor 4XES
TM1 52 1.58x58 μ receptor 6DDE 5-HT2B receptor 4IB4
TM1 53 1.59x59 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 54 1.60x60 μ receptor 6DDE PAF receptor 5ZKQ
ICL1 55 - - - -
ICL1 56 apelin receptor 5VBL - -
ICL1 57 apelin receptor 5VBL - -
ICL1 58 apelin receptor 5VBL - -
ICL1 59 - - - -
TM2 60 2.37x37 5-HT2C receptor 6BQH PAR1 3VW7
TM2 61 2.38x38 μ receptor 6DDE apelin receptor 5VBL
TM2 62 2.39x39 μ receptor 6DDE FFA1 receptor 5TZY
TM2 63 2.40x40 μ receptor 6DDE S1P1 receptor 3V2Y
TM2 64 2.41x41 μ receptor 6DDE - -
TM2 65 2.42x42 μ receptor 6DDE μ receptor 6DDE
TM2 66 2.43x43 μ receptor 6DDE NTS1 receptor 4XES
TM2 67 2.44x44 μ receptor 6DDE PAR1 3VW7
TM2 68 2.45x45 μ receptor 6DDE - -
TM2 69 2.46x46 μ receptor 6DDE μ receptor 6DDE
TM2 70 2.47x47 μ receptor 6DDE μ receptor 6DDE
TM2 71 2.48x48 μ receptor 6DDE A2A receptor 4UHR
TM2 72 2.49x49 μ receptor 6DDE μ receptor 6DDE
TM2 73 2.50x50 μ receptor 6DDE μ receptor 6DDE
TM2 74 2.51x51 μ receptor 6DDE A2A receptor 4UHR
TM2 75 2.52x52 μ receptor 6DDE μ receptor 6DDE
TM2 76 2.53x53 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 77 2.54x54 μ receptor 6DDE NTS1 receptor 4XES
TM2 78 2.55x55 μ receptor 6DDE Rhodopsin 5DYS
TM2 79 2.56x56 μ receptor 6DDE - -
TM2 80 2.57x57 μ receptor 6DDE A2A receptor 4UHR
TM2 81 2.58x58 μ receptor 6DDE CB1 receptor 5XRA
TM2 82 2.59x59 μ receptor 6DDE μ receptor 6DDE
TM2 83 2.60x60 μ receptor 6DDE D2 receptor 6CM4
TM2 84 2.61x61 μ receptor 6DDE - -
TM2 85 2.62x62 μ receptor 6DDE P2Y1 receptor 4XNW
TM2 86 2.63x63 μ receptor 6DDE D2 receptor 6CM4
TM2 87 2.64x64 μ receptor 6DDE ETB receptor 5X93
TM2 88 2.65x65 μ receptor 6DDE - -
TM2 89 2.66x66 μ receptor 6DDE US28 4XT1
TM2 90 2.67x67 5-HT2C receptor 6BQH CB1 receptor 5XRA
ECL1 91 - - - -
ECL1 92 - - - -
ECL1 93 - - - -
TM3 94 3.18x18 P2Y12 receptor 4PXZ - -
TM3 95 3.19x19 P2Y12 receptor 4PXZ - -
TM3 96 3.20x20 P2Y12 receptor 4PXZ - -
TM3 97 3.21x21 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 98 3.22x22 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM3 99 3.23x23 μ receptor 6DDE 5-HT2B receptor 4NC3
TM3 100 3.24x24 μ receptor 6DDE US28 5WB1
TM3 101 3.25x25 μ receptor 6DDE - -
TM3 102 3.26x26 μ receptor 6DDE μ receptor 6DDE
TM3 103 3.27x27 μ receptor 6DDE μ receptor 6DDE
TM3 104 3.28x28 μ receptor 6DDE A2A receptor 4UHR
TM3 105 3.29x29 μ receptor 6DDE S1P1 receptor 3V2Y
TM3 106 3.30x30 μ receptor 6DDE P2Y12 receptor 4NTJ
TM3 107 3.31x31 μ receptor 6DDE NTS1 receptor 4XES
TM3 108 3.32x32 μ receptor 6DDE - -
TM3 109 3.33x33 μ receptor 6DDE PAF receptor 5ZKQ
TM3 110 3.34x34 μ receptor 6DDE - -
TM3 111 3.35x35 μ receptor 6DDE OX2 receptor 5WS3
TM3 112 3.36x36 μ receptor 6DDE Y1 receptor 5ZBH
TM3 113 3.37x37 μ receptor 6DDE - -
TM3 114 3.38x38 μ receptor 6DDE μ receptor 6DDE
TM3 115 3.39x39 μ receptor 6DDE μ receptor 6DDE
TM3 116 3.40x40 μ receptor 6DDE μ receptor 6DDE
TM3 117 3.41x41 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 118 3.42x42 μ receptor 6DDE CXCR4 3ODU
TM3 119 3.43x43 μ receptor 6DDE - -
TM3 120 3.44x44 μ receptor 6DDE NTS1 receptor 4BUO
TM3 121 3.45x45 μ receptor 6DDE - -
TM3 122 3.46x46 μ receptor 6DDE NTS1 receptor 4XES
TM3 123 3.47x47 μ receptor 6DDE P2Y12 receptor 4NTJ
TM3 124 3.48x48 μ receptor 6DDE A2A receptor 4UHR
TM3 125 3.49x49 μ receptor 6DDE μ receptor 6DDE
TM3 126 3.50x50 μ receptor 6DDE μ receptor 6DDE
TM3 127 3.51x51 μ receptor 6DDE μ receptor 6DDE
TM3 128 3.52x52 μ receptor 6DDE μ receptor 6DDE
TM3 129 3.53x53 μ receptor 6DDE μ receptor 6DDE
TM3 130 3.54x54 μ receptor 6DDE μ receptor 6DDE
TM3 131 3.55x55 μ receptor 6DDE μ receptor 6DDE
TM3 132 3.56x56 μ receptor 6DDE μ receptor 6DDE
ICL2 133 34.50x50 - - - -
ICL2 134 34.51x51 μ receptor 5C1M A2A receptor 4UHR
ICL2 135 34.52x52 μ receptor 5C1M μ receptor 5C1M
ICL2 136 34.53x53 μ receptor 5C1M A2A receptor 4UHR
ICL2 137 34.54x54 μ receptor 5C1M CCR9 5LWE
ICL2 138 34.55x55 μ receptor 5C1M NTS1 receptor 4XES
ICL2 139 34.56x56 - - - -
TM4 140 4.38x38 μ receptor 6DDE NTS1 receptor 4XES
TM4 141 4.39x39 μ receptor 6DDE - -
TM4 142 4.40x40 μ receptor 6DDE CB1 receptor 5XRA
TM4 143 4.41x41 μ receptor 6DDE BLT1 receptor 5X33
TM4 144 4.42x42 μ receptor 6DDE - -
TM4 145 4.43x43 μ receptor 6DDE D2 receptor 6CM4
TM4 146 4.44x44 μ receptor 6DDE - -
TM4 147 4.45x45 μ receptor 6DDE 5-HT2B receptor 4IB4
TM4 148 4.46x46 μ receptor 6DDE AT2 receptor 5UNG
TM4 149 4.47x47 μ receptor 6DDE κ receptor 4DJH
TM4 150 4.48x48 μ receptor 6DDE 5-HT2B receptor 4IB4
TM4 151 4.49x49 μ receptor 6DDE - -
TM4 152 4.50x50 μ receptor 6DDE - -
TM4 153 4.51x51 μ receptor 6DDE - -
TM4 154 4.52x52 μ receptor 6DDE 5-HT2B receptor 4IB4
TM4 155 4.53x53 μ receptor 6DDE - -
TM4 156 4.54x54 μ receptor 6DDE OX2 receptor 5WS3
TM4 157 4.55x55 μ receptor 6DDE CCR2 5T1A
TM4 158 4.56x56 μ receptor 6DDE NTS1 receptor 4XES
TM4 159 4.57x57 μ receptor 6DDE PAR2 5NDD
TM4 160 4.58x58 μ receptor 6DDE PAF receptor 5ZKQ
TM4 161 4.59x59 μ receptor 6DDE NTS1 receptor 4XES
TM4 162 4.60x60 μ receptor 6DDE NTS1 receptor 4XES
TM4 163 4.61x61 μ receptor 6DDE - -
TM4 164 4.62x62 μ receptor 6DDE PAR2 5NDD
TM4 165 4.63x63 5-HT2C receptor 6BQH - -
TM4 166 4.64x64 5-HT2C receptor 6BQH M1 receptor 5CXV
TM4 167 4.65x65 5-HT2C receptor 6BQH - -
TM4 168 4.66x66 5-HT2C receptor 6BQH - -
TM4 169 4.67x67 5-HT2C receptor 6BQH M2 receptor 3UON
ECL2 170 - - - -
ECL2 171 - - - -
ECL2 172 - - - -
ECL2 173 - - - -
ECL2 174 - - - -
ECL2 175 - - - -
ECL2 176 - - - -
ECL2 177 - - - -
ECL2 178 - - - -
ECL2 179 - - - -
TM5 180 5.35x36 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 181 5.36x37 μ receptor 6DDE - -
TM5 182 5.37x38 μ receptor 6DDE NTS1 receptor 4XES
TM5 183 5.38x39 μ receptor 6DDE μ receptor 6DDE
TM5 184 5.39x40 μ receptor 6DDE NTS1 receptor 4XES
TM5 185 5.40x41 μ receptor 6DDE ETB receptor 5X93
TM5 186 5.41x42 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 187 5.42x43 μ receptor 6DDE CXCR4 3ODU
TM5 188 5.43x44 μ receptor 6DDE - -
TM5 189 5.44x45 μ receptor 6DDE NTS1 receptor 4XES
TM5 190 5.45x46 μ receptor 6DDE BLT1 receptor 5X33
TM5 191 5.46x461 μ receptor 6DDE PAR2 5NDD
TM5 192 5.47x47 μ receptor 6DDE OX2 receptor 5WS3
TM5 193 5.48x48 μ receptor 6DDE NTS1 receptor 4XES
TM5 194 5.49x49 μ receptor 6DDE A2A receptor 4UHR
TM5 195 5.50x50 μ receptor 6DDE μ receptor 6DDE
TM5 196 5.51x51 μ receptor 6DDE D4 receptor 5WIV
TM5 197 5.52x52 μ receptor 6DDE US28 4XT1
TM5 198 5.53x53 μ receptor 6DDE μ receptor 6DDE
TM5 199 5.54x54 μ receptor 6DDE - -
TM5 200 5.55x55 μ receptor 6DDE Y1 receptor 5ZBH
TM5 201 5.56x56 μ receptor 6DDE NTS1 receptor 4XES
TM5 202 5.57x57 μ receptor 6DDE NTS1 receptor 4XES
TM5 203 5.58x58 μ receptor 6DDE NTS1 receptor 4XES
TM5 204 5.59x59 μ receptor 6DDE NOP receptor 5DHG
TM5 205 5.60x60 μ receptor 6DDE CXCR4 3ODU
TM5 206 5.61x61 μ receptor 6DDE NTS1 receptor 4XES
TM5 207 5.62x62 μ receptor 6DDE P2Y1 receptor 4XNW
TM5 208 5.63x63 μ receptor 6DDE 5-HT2C receptor 6BQH
TM5 209 5.64x64 μ receptor 6DDE NTS1 receptor 4XES
TM5 210 5.65x65 μ receptor 6DDE μ receptor 6DDE
TM5 211 5.66x66 μ receptor 6DDE A2A receptor 4UHR
TM5 212 5.67x67 μ receptor 6DDE A2A receptor 4UHR
TM5 213 5.68x68 μ receptor 6DDE P2Y1 receptor 4XNW
ICL3 214 - - - -
ICL3 215 AT2 receptor 5UNG - -
ICL3 216 - - - -
TM6 217 6.24x24 μ receptor 6DDE A2A receptor 4UHR
TM6 218 6.25x25 μ receptor 6DDE - -
TM6 219 6.26x26 μ receptor 6DDE NTS1 receptor 4BUO
TM6 220 6.27x27 μ receptor 6DDE CXCR4 3ODU
TM6 221 6.28x28 μ receptor 6DDE - -
TM6 222 6.29x29 μ receptor 6DDE PAR1 3VW7
TM6 223 6.30x30 μ receptor 6DDE Y1 receptor 5ZBH
TM6 224 6.31x31 μ receptor 6DDE US28 4XT1
TM6 225 6.32x32 μ receptor 6DDE PAR2 5NDD
TM6 226 6.33x33 μ receptor 6DDE OX2 receptor 5WS3
TM6 227 6.34x34 μ receptor 6DDE μ receptor 6DDE
TM6 228 6.35x35 μ receptor 6DDE FFA1 receptor 5TZY
TM6 229 6.36x36 μ receptor 6DDE AT1 receptor 4ZUD
TM6 230 6.37x37 μ receptor 6DDE NTS1 receptor 4XES
TM6 231 6.38x38 μ receptor 6DDE CCR2 5T1A
TM6 232 6.39x39 μ receptor 6DDE CCR2 5T1A
TM6 233 6.40x40 μ receptor 6DDE A2A receptor 4UHR
TM6 234 6.41x41 μ receptor 6DDE - -
TM6 235 6.42x42 μ receptor 6DDE S1P1 receptor 3V2Y
TM6 236 6.43x43 μ receptor 6DDE LPA6 receptor 5XSZ
TM6 237 6.44x44 μ receptor 6DDE μ receptor 6DDE
TM6 238 6.45x45 μ receptor 6DDE A2A receptor 4UHR
TM6 239 6.46x46 μ receptor 6DDE - -
TM6 240 6.47x47 μ receptor 6DDE - -
TM6 241 6.48x48 μ receptor 6DDE μ receptor 6DDE
TM6 242 6.49x49 μ receptor 6DDE δ receptor 4N6H
TM6 243 6.50x50 μ receptor 6DDE μ receptor 6DDE
TM6 244 6.51x51 μ receptor 6DDE - -
TM6 245 6.52x52 μ receptor 6DDE - -
TM6 246 6.53x53 μ receptor 6DDE μ receptor 6DDE
TM6 247 6.54x54 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 248 6.55x55 μ receptor 6DDE κ receptor 4DJH
TM6 249 6.56x56 μ receptor 6DDE NTS1 receptor 4XES
TM6 250 6.57x57 μ receptor 6DDE CB1 receptor 5XRA
TM6 251 6.58x58 μ receptor 6DDE PAR2 5NDD
TM6 252 6.59x59 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 253 6.60x60 μ receptor 6DDE NTS1 receptor 4XES
TM6 254 6.61x61 μ receptor 6DDE κ receptor 4DJH
ECL3 255 - - - -
ECL3 256 δ receptor 4N6H - -
ECL3 257 δ receptor 4N6H - -
ECL3 258 δ receptor 4N6H - -
ECL3 259 - - - -
TM7 260 7.28x27 5-HT2C receptor 6BQH OX2 receptor 5WS3
TM7 261 7.29x28 5-HT2C receptor 6BQH - -
TM7 262 7.30x29 μ receptor 6DDE 5-HT2C receptor 6BQH
TM7 263 7.31x30 μ receptor 6DDE PAR2 5NDD
TM7 264 7.32x31 μ receptor 6DDE NTS1 receptor 4XES
TM7 265 7.33x32 μ receptor 6DDE CCR9 5LWE
TM7 266 7.34x33 μ receptor 6DDE - -
TM7 267 7.35x34 μ receptor 6DDE FFA1 receptor 5KW2
TM7 268 7.36x35 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM7 269 7.37x36 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 270 7.38x37 μ receptor 6DDE PAR2 5NDD
TM7 271 7.39x38 μ receptor 6DDE NTS1 receptor 4XES
TM7 272 7.40x39 μ receptor 6DDE CB1 receptor 5XRA
TM7 273 7.41x40 μ receptor 6DDE μ receptor 6DDE
TM7 274 7.42x41 μ receptor 6DDE NTS1 receptor 4GRV
TM7 275 7.43x42 μ receptor 6DDE CB1 receptor 5XRA
TM7 276 7.44x43 μ receptor 6DDE PAR2 5NDD
TM7 277 7.45x45 μ receptor 6DDE μ receptor 6DDE
TM7 278 7.46x46 μ receptor 6DDE Y1 receptor 5ZBH
TM7 279 7.47x47 μ receptor 6DDE NTS1 receptor 4XES
TM7 280 7.48x48 μ receptor 6DDE NTS1 receptor 4XES
TM7 281 7.49x49 μ receptor 6DDE μ receptor 6DDE
TM7 282 7.50x50 μ receptor 6DDE - -
TM7 283 7.51x51 μ receptor 6DDE PAR2 5NDD
TM7 284 7.52x52 μ receptor 6DDE μ receptor 6DDE
TM7 285 7.53x53 μ receptor 6DDE μ receptor 6DDE
TM7 286 7.54x54 μ receptor 6DDE PAF receptor 5ZKQ
TM7 287 7.55x55 5-HT2C receptor 6BQH PAR2 5NDD
TM7 288 7.56x56 5-HT2C receptor 6BQH - -
H8 289 8.47x47 5-HT2C receptor 6BQH PAR2 5NDD
H8 290 8.48x48 5-HT2C receptor 6BQH 5-HT2B receptor 5TVN
H8 291 8.49x49 5-HT2C receptor 6BQH AT2 receptor 5UNG
H8 292 8.50x50 5-HT2C receptor 6BQH 5-HT2B receptor 4IB4
H8 293 8.51x51 5-HT2C receptor 6BQH 5-HT2B receptor 4IB4
H8 294 8.52x52 5-HT2C receptor 6BQH M3 receptor 4U15
H8 295 8.53x53 5-HT2C receptor 6BQH - -
H8 296 8.54x54 5-HT2C receptor 6BQH PAR2 5NDD
H8 297 8.55x55 5-HT2C receptor 6BQH - -
H8 298 8.56x56 5-HT2C receptor 6BQH OX2 receptor 5WS3
H8 299 8.57x57 5-HT2C receptor 6BQH NTS1 receptor 4BUO
H8 300 8.58x58 5-HT2C receptor 6BQH PAR2 5NDD
H8 301 8.59x59 5-HT2C receptor 6BQH CCR9 5LWE
H8 302 8.60x60 5-HT2C receptor 6BQH - -
C-term 303 - - - -
C-term 304 - - - -
C-term 305 - - - -
C-term 306 - - - -
C-term 307 - - - -