GPR148 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 8.81 docs)

VERSION

2018-07-10

MAIN TEMPLATE

5-HT1B receptor (sequence similarity: 36%) PDB: 6G79

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 77.2 9.3 13.5
Side-chains 11.8 50.2 38.1

Number of backbone templates: 8
Number of rotamer templates: 42

NGL is a WebGL based 3D viewer powered by MMTF.

6G79
4IAQ
4XES
3V2Y
5DSG
3SN6
6D9H
5ZKP
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 40 - - - -
N-term 41 - - - -
N-term 42 - - - -
N-term 43 - - - -
N-term 44 - - - -
TM1 45 1.28x28 5-HT1B receptor 6G79 Y1 receptor 5ZBH
TM1 46 1.29x29 5-HT1B receptor 6G79 A1 receptor 5UEN
TM1 47 1.30x30 5-HT1B receptor 6G79 CB1 receptor 5XRA
TM1 48 1.31x31 5-HT1B receptor 6G79 Y1 receptor 5ZBH
TM1 49 1.32x32 5-HT1B receptor 6G79 - -
TM1 50 1.33x33 5-HT1B receptor 6G79 ETB receptor 5X93
TM1 51 1.34x34 5-HT1B receptor 6G79 - -
TM1 52 1.35x35 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM1 53 1.36x36 5-HT1B receptor 6G79 FFA1 receptor 5TZY
TM1 54 1.37x37 5-HT1B receptor 6G79 M2 receptor 4MQT
TM1 55 1.38x38 5-HT1B receptor 6G79 - -
TM1 56 1.39x39 5-HT1B receptor 6G79 CB1 receptor 5XRA
TM1 57 1.40x40 5-HT1B receptor 6G79 β2-adrenoceptor 3SN6
TM1 58 1.41x41 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM1 59 1.42x42 5-HT1B receptor 6G79 M2 receptor 4MQT
TM1 60 1.43x43 5-HT1B receptor 6G79 A1 receptor 6D9H
TM1 61 1.44x44 5-HT1B receptor 6G79 D2 receptor 6CM4
TM1 62 1.45x45 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM1 63 1.46x46 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM1 64 1.47x47 5-HT1B receptor 6G79 κ receptor 6B73
TM1 65 1.48x48 5-HT1B receptor 6G79 D4 receptor 5WIV
TM1 66 1.49x49 5-HT1B receptor 6G79 AT2 receptor 5UNG
TM1 67 1.50x50 5-HT1B receptor 6G79 - -
TM1 68 1.51x51 5-HT1B receptor 6G79 - -
TM1 69 1.52x52 5-HT1B receptor 6G79 β2-adrenoceptor 3SN6
TM1 70 1.53x53 5-HT1B receptor 6G79 Y1 receptor 5ZBH
TM1 71 1.54x54 5-HT1B receptor 6G79 NTS1 receptor 5T04
TM1 72 1.55x55 5-HT1B receptor 6G79 M2 receptor 4MQT
TM1 73 1.56x56 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM1 74 1.57x57 5-HT1B receptor 6G79 β2-adrenoceptor 3SN6
TM1 75 1.58x58 5-HT1B receptor 6G79 CB1 receptor 5XRA
TM1 76 1.59x59 5-HT1B receptor 6G79 μ receptor 5C1M
TM1 77 1.60x60 5-HT1B receptor 6G79 A1 receptor 6D9H
ICL1 78 12.48x48 - - - -
ICL1 79 12.49x49 5-HT1B receptor 4IAQ β2-adrenoceptor 4LDE
ICL1 80 12.50x50 5-HT1B receptor 4IAQ 5-HT1B receptor 4IAQ
ICL1 81 12.51x51 - - - -
TM2 82 2.36x36 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 83 2.37x37 5-HT1B receptor 6G79 - -
TM2 84 2.38x38 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM2 85 2.39x39 5-HT1B receptor 6G79 - -
TM2 86 2.40x40 5-HT1B receptor 6G79 CB1 receptor 5XRA
TM2 87 2.41x41 5-HT1B receptor 6G79 H1 receptor 3RZE
TM2 88 2.42x42 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM2 89 2.43x43 5-HT1B receptor 6G79 - -
TM2 90 2.44x44 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM2 91 2.45x45 5-HT1B receptor 6G79 κ receptor 6B73
TM2 92 2.46x46 5-HT1B receptor 6G79 - -
TM2 93 2.47x47 5-HT1B receptor 6G79 - -
TM2 94 2.48x48 5-HT1B receptor 6G79 κ receptor 6B73
TM2 95 2.49x49 5-HT1B receptor 6G79 NTS1 receptor 5T04
TM2 96 2.50x50 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM2 97 2.51x51 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM2 98 2.52x52 5-HT1B receptor 6G79 A1 receptor 6D9H
TM2 99 2.53x53 5-HT1B receptor 6G79 P2Y1 receptor 4XNW
TM2 100 2.54x54 5-HT1B receptor 6G79 ETB receptor 5X93
TM2 101 2.55x55 S1P1 receptor 3V2Y β2-adrenoceptor 3SN6
TM2 102 2.56x56 S1P1 receptor 3V2Y - -
TM2 103 2.57x57 5-HT1B receptor 6G79 - -
TM2 104 2.58x58 5-HT1B receptor 6G79 - -
TM2 105 2.59x59 5-HT1B receptor 6G79 A1 receptor 6D9H
TM2 106 2.60x60 5-HT1B receptor 6G79 Rhodopsin 5DYS
TM2 107 2.61x61 5-HT1B receptor 6G79 κ receptor 6B73
TM2 108 2.62x62 5-HT1B receptor 6G79 PAR1 3VW7
TM2 109 2.63x63 5-HT1B receptor 6G79 D4 receptor 5WIV
TM2 110 2.64x64 5-HT1B receptor 6G79 A2A receptor 5G53
TM2 111 2.65x65 5-HT1B receptor 6G79 β2-adrenoceptor 3SN6
TM2 112 2.66x66 5-HT1B receptor 6G79 A2A receptor 5G53
ECL1 113 23.49x49 - - - -
ECL1 114 23.50x50 5-HT1B receptor 4IAQ 5-HT1B receptor 4IAQ
ECL1 115 23.51x51 5-HT1B receptor 4IAQ - -
ECL1 116 23.52x52 - - - -
TM3 117 3.21x21 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM3 118 3.22x22 5-HT1B receptor 6G79 5-HT2C receptor 6BQG
TM3 119 3.23x23 5-HT1B receptor 6G79 - -
TM3 120 3.24x24 5-HT1B receptor 6G79 M1 receptor 5CXV
TM3 121 3.25x25 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM3 122 3.26x26 5-HT1B receptor 6G79 - -
TM3 123 3.27x27 5-HT1B receptor 6G79 κ receptor 6B73
TM3 124 3.28x28 5-HT1B receptor 6G79 US28 4XT1
TM3 125 3.29x29 5-HT1B receptor 6G79 β2-adrenoceptor 3SN6
TM3 126 3.30x30 5-HT1B receptor 6G79 - -
TM3 127 3.31x31 5-HT1B receptor 6G79 PAR1 3VW7
TM3 128 3.32x32 5-HT1B receptor 6G79 A1 receptor 6D9H
TM3 129 3.33x33 5-HT1B receptor 6G79 PAF receptor 5ZKP
TM3 130 3.34x34 5-HT1B receptor 6G79 NTS1 receptor 5T04
TM3 131 3.35x35 5-HT1B receptor 6G79 US28 4XT1
TM3 132 3.36x36 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM3 133 3.37x37 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM3 134 3.38x38 5-HT1B receptor 6G79 A1 receptor 6D9H
TM3 135 3.39x39 5-HT1B receptor 6G79 NTS1 receptor 5T04
TM3 136 3.40x40 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM3 137 3.41x41 5-HT1B receptor 6G79 A1 receptor 6D9H
TM3 138 3.42x42 5-HT1B receptor 6G79 CB1 receptor 5XRA
TM3 139 3.43x43 5-HT1B receptor 6G79 - -
TM3 140 3.44x44 5-HT1B receptor 6G79 κ receptor 6B73
TM3 141 3.45x45 5-HT1B receptor 6G79 A1 receptor 6D9H
TM3 142 3.46x46 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM3 143 3.47x47 5-HT1B receptor 6G79 - -
TM3 144 3.48x48 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM3 145 3.49x49 5-HT1B receptor 6G79 P2Y1 receptor 4XNW
TM3 146 3.50x50 5-HT1B receptor 6G79 - -
TM3 147 3.51x51 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM3 148 3.52x52 5-HT1B receptor 6G79 A1 receptor 6D9H
TM3 149 3.53x53 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM3 150 3.54x54 5-HT1B receptor 6G79 A1 receptor 6D9H
TM3 151 3.55x55 5-HT1B receptor 6G79 AT2 receptor 5UNG
TM3 152 3.56x56 5-HT1B receptor 6G79 CCR2 5T1A
ICL2 153 34.50x50 - - - -
ICL2 154 34.51x51 5-HT1B receptor 4IAQ A1 receptor 6D9H
ICL2 155 34.52x52 5-HT1B receptor 4IAQ A1 receptor 6D9H
ICL2 156 34.53x53 5-HT1B receptor 4IAQ 5-HT1B receptor 4IAQ
ICL2 157 34.54x54 5-HT1B receptor 4IAQ κ receptor 6B73
ICL2 158 34.55x55 5-HT1B receptor 4IAQ β2-adrenoceptor 3SN6
ICL2 159 34.56x56 5-HT1B receptor 4IAQ κ receptor 6B73
ICL2 160 34.57x57 - - - -
TM4 161 4.38x38 5-HT1B receptor 6G79 NTS1 receptor 5T04
TM4 162 4.39x39 5-HT1B receptor 6G79 - -
TM4 163 4.40x40 5-HT1B receptor 6G79 PAR1 3VW7
TM4 164 4.41x41 5-HT1B receptor 6G79 CXCR4 3ODU
TM4 165 4.42x42 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM4 166 4.43x43 5-HT1B receptor 6G79 C5a1 receptor 5O9H
TM4 167 4.44x44 5-HT1B receptor 6G79 NTS1 receptor 5T04
TM4 168 4.45x45 5-HT1B receptor 6G79 A1 receptor 6D9H
TM4 169 4.46x46 5-HT1B receptor 6G79 AT2 receptor 5UNG
TM4 170 4.47x47 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM4 171 4.48x48 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM4 172 4.49x49 5-HT1B receptor 6G79 κ receptor 6B73
TM4 173 4.50x50 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM4 174 4.51x51 5-HT1B receptor 6G79 κ receptor 6B73
TM4 175 4.52x52 5-HT1B receptor 6G79 β2-adrenoceptor 3SN6
TM4 176 4.53x53 5-HT1B receptor 6G79 CB1 receptor 5XRA
TM4 177 4.54x54 5-HT1B receptor 6G79 AT2 receptor 5UNG
TM4 178 4.55x55 5-HT1B receptor 6G79 FFA1 receptor 5TZY
TM4 179 4.56x56 5-HT1B receptor 6G79 - -
TM4 180 4.57x57 5-HT1B receptor 6G79 - -
TM4 181 4.58x58 5-HT1B receptor 6G79 - -
TM4 182 4.59x59 5-HT1B receptor 6G79 - -
TM4 183 4.60x60 M4 receptor 5DSG - -
TM4 184 4.61x61 M4 receptor 5DSG M4 receptor 5DSG
TM4 185 4.62x62 M4 receptor 5DSG - -
TM4 186 4.63x63 M4 receptor 5DSG κ receptor 6B73
ECL2 187 - - - -
ECL2 188 - - - -
ECL2 189 - - - -
ECL2 190 - - - -
ECL2 191 - - - -
ECL2 192 - - - -
ECL2 193 - - - -
ECL2 194 - - - -
ECL2 195 - - - -
TM5 196 5.35x36 5-HT1B receptor 6G79 M3 receptor 4U15
TM5 197 5.36x37 5-HT1B receptor 6G79 β2-adrenoceptor 3SN6
TM5 198 5.37x38 5-HT1B receptor 6G79 AT2 receptor 5UNG
TM5 199 5.38x39 5-HT1B receptor 6G79 FFA1 receptor 5TZY
TM5 200 5.39x40 5-HT1B receptor 6G79 PAR1 3VW7
TM5 201 5.40x41 5-HT1B receptor 6G79 P2Y12 receptor 4NTJ
TM5 202 5.41x42 5-HT1B receptor 6G79 5-HT2C receptor 6BQG
TM5 203 5.42x43 5-HT1B receptor 6G79 US28 4XT1
TM5 204 5.43x44 5-HT1B receptor 6G79 - -
TM5 205 5.44x45 5-HT1B receptor 6G79 - -
TM5 206 5.45x46 5-HT1B receptor 6G79 PAF receptor 5ZKP
TM5 207 5.46x461 5-HT1B receptor 6G79 P2Y1 receptor 4XNW
TM5 208 5.47x47 5-HT1B receptor 6G79 - -
TM5 209 5.48x48 5-HT1B receptor 6G79 Rhodopsin 4ZWJ
TM5 210 5.49x49 5-HT1B receptor 6G79 - -
TM5 211 5.50x50 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM5 212 5.51x51 5-HT1B receptor 6G79 CXCR4 3ODU
TM5 213 5.52x52 5-HT1B receptor 6G79 OX2 receptor 5WS3
TM5 214 5.53x53 5-HT1B receptor 6G79 - -
TM5 215 5.54x54 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM5 216 5.55x55 5-HT1B receptor 6G79 A2A receptor 5G53
TM5 217 5.56x56 5-HT1B receptor 6G79 M2 receptor 4MQT
TM5 218 5.57x57 5-HT1B receptor 6G79 A1 receptor 6D9H
TM5 219 5.58x58 5-HT1B receptor 6G79 - -
TM5 220 5.59x59 5-HT1B receptor 6G79 κ receptor 6B73
TM5 221 5.60x60 5-HT1B receptor 6G79 CB1 receptor 5XRA
TM5 222 5.61x61 5-HT1B receptor 6G79 5-HT2C receptor 6BQG
TM5 223 5.62x62 5-HT1B receptor 6G79 M2 receptor 4MQT
TM5 224 5.63x63 5-HT1B receptor 6G79 D2 receptor 6CM4
TM5 225 5.64x64 5-HT1B receptor 6G79 A1 receptor 6D9H
TM5 226 5.65x65 5-HT1B receptor 6G79 - -
TM5 227 5.66x66 5-HT1B receptor 6G79 - -
TM5 228 5.67x67 5-HT1B receptor 6G79 - -
TM5 229 5.68x68 5-HT1B receptor 6G79 - -
TM5 230 5.69x69 5-HT1B receptor 6G79 β2-adrenoceptor 3SN6
TM5 231 5.70x70 β2-adrenoceptor 3SN6 - -
TM5 232 5.71x71 β2-adrenoceptor 3SN6 - -
TM5 233 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 234 5.73x73 β2-adrenoceptor 3SN6 - -
TM5 235 5.74x74 β2-adrenoceptor 3SN6 - -
TM5 236 5.75x75 β2-adrenoceptor 3SN6 - -
TM5 237 5.76x76 β2-adrenoceptor 3SN6 - -
ICL3 238 - - - -
ICL3 239 - - - -
ICL3 240 - - - -
ICL3 241 - - - -
ICL3 242 - - - -
ICL3 248 - - - -
ICL3 249 - - - -
ICL3 250 - - - -
ICL3 251 - - - -
ICL3 252 - - - -
TM6 253 6.24x24 A1 receptor 6D9H AT2 receptor 5UNG
TM6 254 6.25x25 A1 receptor 6D9H 5-HT2C receptor 6BQG
TM6 255 6.26x26 5-HT1B receptor 6G79 - -
TM6 256 6.27x27 5-HT1B receptor 6G79 A1 receptor 6D9H
TM6 257 6.28x28 5-HT1B receptor 6G79 M2 receptor 4MQT
TM6 258 6.29x29 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM6 259 6.30x30 5-HT1B receptor 6G79 - -
TM6 260 6.31x31 5-HT1B receptor 6G79 5-HT2C receptor 6BQG
TM6 261 6.32x32 5-HT1B receptor 6G79 - -
TM6 262 6.33x33 5-HT1B receptor 6G79 OX2 receptor 5WS3
TM6 263 6.34x34 5-HT1B receptor 6G79 β2-adrenoceptor 4LDE
TM6 264 6.35x35 5-HT1B receptor 6G79 NTS1 receptor 5T04
TM6 265 6.36x36 5-HT1B receptor 6G79 apelin receptor 5VBL
TM6 266 6.37x37 5-HT1B receptor 6G79 - -
TM6 267 6.38x38 5-HT1B receptor 6G79 M1 receptor 5CXV
TM6 268 6.39x39 5-HT1B receptor 6G79 κ receptor 6B73
TM6 269 6.40x40 5-HT1B receptor 6G79 apelin receptor 5VBL
TM6 270 6.41x41 5-HT1B receptor 6G79 CXCR4 3ODU
TM6 271 6.42x42 5-HT1B receptor 6G79 CCR9 5LWE
TM6 272 6.43x43 5-HT1B receptor 6G79 A1 receptor 6D9H
TM6 273 6.44x44 5-HT1B receptor 6G79 CCR5 5UIW
TM6 274 6.45x45 5-HT1B receptor 6G79 κ receptor 6B73
TM6 275 6.46x46 5-HT1B receptor 6G79 - -
TM6 276 6.47x47 5-HT1B receptor 6G79 M2 receptor 4MQT
TM6 277 6.48x48 5-HT1B receptor 6G79 FFA1 receptor 5KW2
TM6 278 6.49x49 5-HT1B receptor 6G79 Rhodopsin 4ZWJ
TM6 279 6.50x50 5-HT1B receptor 6G79 - -
TM6 280 6.51x51 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM6 281 6.52x52 5-HT1B receptor 6G79 OX2 receptor 5WS3
TM6 282 6.53x53 5-HT1B receptor 6G79 US28 4XT1
TM6 283 6.54x54 5-HT1B receptor 6G79 - -
TM6 284 6.55x55 5-HT1B receptor 6G79 CB1 receptor 5XRA
TM6 285 6.56x56 5-HT1B receptor 6G79 CB1 receptor 5XRA
TM6 286 6.57x57 5-HT1B receptor 6G79 5-HT2C receptor 6BQG
TM6 287 6.58x58 5-HT1B receptor 6G79 - -
ECL3 288 - - - -
ECL3 289 - - - -
ECL3 290 - - - -
ECL3 291 - - - -
ECL3 292 - - - -
ECL3 293 5-HT1B receptor 6G79 - -
ECL3 294 5-HT1B receptor 6G79 - -
TM7 295 7.36x35 5-HT1B receptor 6G79 - -
TM7 296 7.37x36 5-HT1B receptor 6G79 - -
TM7 297 7.38x37 5-HT1B receptor 6G79 - -
TM7 298 7.39x38 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM7 299 7.40x39 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM7 300 7.41x40 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM7 301 7.42x41 5-HT1B receptor 6G79 PAF receptor 5ZKP
TM7 302 7.43x42 5-HT1B receptor 6G79 FFA1 receptor 5TZY
TM7 303 7.44x43 5-HT1B receptor 6G79 NTS1 receptor 5T04
TM7 304 7.45x45 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM7 305 7.46x46 5-HT1B receptor 6G79 5-HT1B receptor 6G79
TM7 306 7.47x47 5-HT1B receptor 6G79 - -
TM7 307 7.48x48 5-HT1B receptor 6G79 5-HT2B receptor 5TUD
TM7 308 7.49x49 5-HT1B receptor 6G79 - -
TM7 309 7.50x50 5-HT1B receptor 6G79 - -
TM7 310 7.51x51 5-HT1B receptor 6G79 M1 receptor 5CXV
TM7 311 7.52x52 5-HT1B receptor 6G79 μ receptor 6DDF
TM7 312 7.53x53 5-HT1B receptor 6G79 - -
TM7 313 7.54x54 5-HT1B receptor 6G79 - -
TM7 314 7.55x55 5-HT1B receptor 6G79 - -
TM7 315 7.56x56 5-HT1B receptor 6G79 Rhodopsin 4ZWJ
TM7 316 7.57x57 PAF receptor 5ZKP - -
H8 317 8.47x47 5-HT1B receptor 6G79 - -
H8 318 8.48x48 5-HT1B receptor 6G79 - -
H8 319 8.49x49 5-HT1B receptor 6G79 - -
H8 320 8.50x50 5-HT1B receptor 6G79 5-HT2C receptor 6BQG
H8 321 8.51x51 5-HT1B receptor 6G79 - -
H8 322 8.52x52 5-HT1B receptor 6G79 - -
H8 323 8.53x53 5-HT1B receptor 6G79 - -
H8 324 8.54x54 5-HT1B receptor 6G79 - -
H8 325 8.55x55 5-HT1B receptor 6G79 CB1 receptor 5XRA
H8 326 8.56x56 5-HT1B receptor 6G79 LPA1 receptor 4Z36
H8 327 8.57x57 5-HT1B receptor 6G79 5-HT1B receptor 6G79
H8 328 8.58x58 5-HT1B receptor 6G79 β2-adrenoceptor 3SN6
C-term 329 5-HT1B receptor 6G79 5-HT1B receptor 6G79
C-term 330 - - - -
C-term 331 - - - -
C-term 332 - - - -
C-term 333 - - - -