GPR152 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 6.31 docs)

VERSION

2018-07-10

MAIN TEMPLATE

NTS1 receptor (sequence similarity: 38%) PDB: 5T04

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 73.9 16.9 9.2
Side-chains 17.6 53.6 28.8

Number of backbone templates: 6
Number of rotamer templates: 36

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5T04
4BUO
5O9H
5X33
3ODU
5UNG
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 21 NTS1 receptor 5T04 NTS1 receptor 5T04
N-term 22 NTS1 receptor 5T04 NTS1 receptor 5T04
N-term 23 NTS1 receptor 5T04 NTS1 receptor 5T04
N-term 24 NTS1 receptor 5T04 NTS1 receptor 5T04
N-term 25 NTS1 receptor 5T04 NTS1 receptor 5T04
TM1 26 1.29x29 NTS1 receptor 5T04 - -
TM1 27 1.30x30 NTS1 receptor 5T04 5-HT1B receptor 6G79
TM1 28 1.31x31 NTS1 receptor 5T04 Rhodopsin 5DYS
TM1 29 1.32x32 NTS1 receptor 5T04 D4 receptor 5WIV
TM1 30 1.33x33 NTS1 receptor 5T04 - -
TM1 31 1.34x34 NTS1 receptor 5T04 - -
TM1 32 1.35x35 NTS1 receptor 5T04 - -
TM1 33 1.36x36 NTS1 receptor 5T04 NTS1 receptor 5T04
TM1 34 1.37x37 NTS1 receptor 5T04 CB1 receptor 5XRA
TM1 35 1.38x38 NTS1 receptor 5T04 - -
TM1 36 1.39x39 NTS1 receptor 5T04 5-HT2B receptor 5TUD
TM1 37 1.40x40 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM1 38 1.41x41 NTS1 receptor 5T04 NTS1 receptor 5T04
TM1 39 1.42x42 NTS1 receptor 5T04 NTS1 receptor 5T04
TM1 40 1.43x43 NTS1 receptor 5T04 - -
TM1 41 1.44x44 NTS1 receptor 5T04 M2 receptor 4MQT
TM1 42 1.45x45 NTS1 receptor 5T04 Rhodopsin 5DYS
TM1 43 1.46x46 NTS1 receptor 5T04 NTS1 receptor 5T04
TM1 44 1.47x47 NTS1 receptor 5T04 μ receptor 5C1M
TM1 45 1.48x48 NTS1 receptor 5T04 Rhodopsin 5DYS
TM1 46 1.49x49 NTS1 receptor 5T04 PAF receptor 5ZKP
TM1 47 1.50x50 NTS1 receptor 5T04 NTS1 receptor 5T04
TM1 48 1.51x51 NTS1 receptor 5T04 PAF receptor 5ZKP
TM1 49 1.52x52 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM1 50 1.53x53 NTS1 receptor 5T04 - -
TM1 51 1.54x54 NTS1 receptor 5T04 - -
TM1 52 1.55x55 NTS1 receptor 5T04 PAF receptor 5ZKP
TM1 53 1.56x56 NTS1 receptor 5T04 AT2 receptor 5UNG
TM1 54 1.57x57 C5a1 receptor 5O9H FFA1 receptor 5TZY
TM1 55 1.58x58 C5a1 receptor 5O9H CXCR4 3ODU
TM1 56 1.59x59 C5a1 receptor 5O9H H1 receptor 3RZE
TM1 57 1.60x60 C5a1 receptor 5O9H AT2 receptor 5UNF
ICL1 58 - - - -
ICL1 59 - - - -
ICL1 60 - - - -
ICL1 61 - - - -
ICL1 62 - - - -
ICL1 63 - - - -
TM2 64 2.37x37 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 65 2.38x38 C5a1 receptor 5O9H - -
TM2 66 2.39x39 C5a1 receptor 5O9H Rhodopsin 5DYS
TM2 67 2.40x40 NTS1 receptor 5T04 C5a1 receptor 5O9H
TM2 68 2.41x41 NTS1 receptor 5T04 H1 receptor 3RZE
TM2 69 2.42x42 NTS1 receptor 5T04 5-HT1B receptor 6G79
TM2 70 2.43x43 NTS1 receptor 5T04 NTS1 receptor 5T04
TM2 71 2.44x44 NTS1 receptor 5T04 Rhodopsin 5DYS
TM2 72 2.45x45 NTS1 receptor 5T04 NTS1 receptor 5T04
TM2 73 2.46x46 NTS1 receptor 5T04 NTS1 receptor 5T04
TM2 74 2.47x47 NTS1 receptor 5T04 NTS1 receptor 5T04
TM2 75 2.48x48 NTS1 receptor 5T04 NTS1 receptor 5T04
TM2 76 2.49x49 NTS1 receptor 5T04 NTS1 receptor 5T04
TM2 77 2.50x50 NTS1 receptor 5T04 NTS1 receptor 5T04
TM2 78 2.51x51 NTS1 receptor 5T04 C5a1 receptor 5O9H
TM2 79 2.52x52 NTS1 receptor 5T04 NTS1 receptor 5T04
TM2 80 2.53x53 NTS1 receptor 5T04 LPA6 receptor 5XSZ
TM2 81 2.54x54 NTS1 receptor 5T04 NTS1 receptor 5T04
TM2 82 2.55x55 C5a1 receptor 5O9H AT2 receptor 5UNG
TM2 83 2.56x56 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 84 2.57x57 NTS1 receptor 5T04 BLT1 receptor 5X33
TM2 85 2.58x58 NTS1 receptor 5T04 - -
TM2 86 2.59x59 NTS1 receptor 5T04 μ receptor 5C1M
TM2 87 2.60x60 NTS1 receptor 5T04 μ receptor 5C1M
TM2 88 2.61x61 NTS1 receptor 5T04 PAF receptor 5ZKP
TM2 89 2.62x62 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM2 90 2.63x63 NTS1 receptor 5T04 FFA1 receptor 5TZY
TM2 91 2.64x64 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM2 92 2.65x65 NTS1 receptor 5T04 - -
TM2 93 2.66x66 NTS1 receptor 5T04 Rhodopsin 5DYS
TM2 94 2.67x67 NTS1 receptor 5T04 Rhodopsin 6FK6
ECL1 95 - - - -
ECL1 96 23.49x49 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 97 23.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 98 23.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 99 23.52x52 - - - -
TM3 100 3.21x21 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 101 3.22x22 NTS1 receptor 5T04 apelin receptor 5VBL
TM3 102 3.23x23 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 103 3.24x24 NTS1 receptor 5T04 C5a1 receptor 5O9H
TM3 104 3.25x25 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 105 3.26x26 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 106 3.27x27 NTS1 receptor 5T04 β2-adrenoceptor 3SN6
TM3 107 3.28x28 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 108 3.29x29 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 109 3.30x30 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 110 3.31x31 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 111 3.32x32 NTS1 receptor 5T04 - -
TM3 112 3.33x33 NTS1 receptor 5T04 BLT1 receptor 5X33
TM3 113 3.34x34 NTS1 receptor 5T04 M2 receptor 4MQT
TM3 114 3.35x35 NTS1 receptor 5T04 CB1 receptor 5XRA
TM3 115 3.36x36 NTS1 receptor 5T04 CCR2 5T1A
TM3 116 3.37x37 NTS1 receptor 5T04 OX2 receptor 5WS3
TM3 117 3.38x38 NTS1 receptor 5T04 A2A receptor 5G53
TM3 118 3.39x39 NTS1 receptor 5T04 CCR2 5T1A
TM3 119 3.40x40 NTS1 receptor 5T04 Rhodopsin 5DYS
TM3 120 3.41x41 NTS1 receptor 5T04 AT2 receptor 5UNG
TM3 121 3.42x42 NTS1 receptor 5T04 C5a1 receptor 5O9H
TM3 122 3.43x43 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM3 123 3.44x44 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 124 3.45x45 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM3 125 3.46x46 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 126 3.47x47 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 127 3.48x48 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM3 128 3.49x49 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM3 129 3.50x50 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 130 3.51x51 NTS1 receptor 5T04 - -
TM3 131 3.52x52 NTS1 receptor 5T04 NTS1 receptor 5T04
TM3 132 3.53x53 NTS1 receptor 5T04 C5a1 receptor 5O9H
TM3 133 3.54x54 NTS1 receptor 5T04 FFA1 receptor 5TZY
TM3 134 3.55x55 NTS1 receptor 5T04 - -
TM3 135 3.56x56 NTS1 receptor 5T04 - -
ICL2 136 34.50x50 - - - -
ICL2 137 34.51x51 C5a1 receptor 5O9H - -
ICL2 138 34.52x52 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 139 34.53x53 C5a1 receptor 5O9H M2 receptor 4MQT
ICL2 140 34.54x54 C5a1 receptor 5O9H M2 receptor 4MQT
ICL2 141 34.55x55 C5a1 receptor 5O9H LPA6 receptor 5XSZ
ICL2 142 34.56x56 C5a1 receptor 5O9H - -
ICL2 143 34.57x57 - - - -
TM4 144 4.38x38 NTS1 receptor 5T04 US28 4XT1
TM4 145 4.39x39 NTS1 receptor 5T04 US28 4XT1
TM4 146 4.40x40 NTS1 receptor 5T04 μ receptor 5C1M
TM4 147 4.41x41 NTS1 receptor 5T04 C5a1 receptor 5O9H
TM4 148 4.42x42 NTS1 receptor 5T04 - -
TM4 149 4.43x43 NTS1 receptor 5T04 D4 receptor 5WIV
TM4 150 4.44x44 NTS1 receptor 5T04 BLT1 receptor 5X33
TM4 151 4.45x45 NTS1 receptor 5T04 μ receptor 5C1M
TM4 152 4.46x46 NTS1 receptor 5T04 LPA6 receptor 5XSZ
TM4 153 4.47x47 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM4 154 4.48x48 NTS1 receptor 5T04 A1 receptor 6D9H
TM4 155 4.49x49 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM4 156 4.50x50 NTS1 receptor 5T04 NTS1 receptor 5T04
TM4 157 4.51x51 NTS1 receptor 5T04 Rhodopsin 5DYS
TM4 158 4.52x52 NTS1 receptor 5T04 μ receptor 5C1M
TM4 159 4.53x53 NTS1 receptor 5T04 AT2 receptor 5UNG
TM4 160 4.54x54 NTS1 receptor 5T04 - -
TM4 161 4.55x55 NTS1 receptor 5T04 NTS1 receptor 5T04
TM4 162 4.56x56 NTS1 receptor 5T04 - -
TM4 163 4.57x57 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM4 164 4.58x59 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM4 165 4.59x60 NTS1 receptor 5T04 NTS1 receptor 5T04
TM4 166 4.60x61 NTS1 receptor 5T04 - -
TM4 167 4.61x62 NTS1 receptor 5T04 NTS1 receptor 5T04
TM4 168 4.62x63 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM4 169 4.63x64 NTS1 receptor 5T04 AT2 receptor 5UNG
TM4 170 4.64x65 NTS1 receptor 5T04 - -
ECL2 171 - - - -
ECL2 172 BLT1 receptor 5X33 - -
ECL2 173 BLT1 receptor 5X33 - -
ECL2 174 BLT1 receptor 5X33 - -
ECL2 175 BLT1 receptor 5X33 - -
ECL2 176 BLT1 receptor 5X33 - -
ECL2 177 BLT1 receptor 5X33 - -
ECL2 178 BLT1 receptor 5X33 - -
ECL2 179 BLT1 receptor 5X33 - -
ECL2 180 BLT1 receptor 5X33 - -
ECL2 181 - - - -
ECL2 182 45.50x50 NTS1 receptor 5T04 NTS1 receptor 5T04
ECL2 183 45.51x51 NTS1 receptor 5T04 A2A receptor 5G53
ECL2 184 45.52x52 NTS1 receptor 5T04 PAR1 3VW7
ECL2 185 - - - -
ECL2 186 CXCR4 3ODU - -
ECL2 187 CXCR4 3ODU - -
ECL2 188 - - - -
TM5 189 5.35x36 NTS1 receptor 5T04 μ receptor 5C1M
TM5 190 5.36x37 NTS1 receptor 5T04 Rhodopsin 5DYS
TM5 191 5.37x38 NTS1 receptor 5T04 μ receptor 5C1M
TM5 192 5.38x39 NTS1 receptor 5T04 - -
TM5 193 5.39x40 NTS1 receptor 5T04 CB1 receptor 5XRA
TM5 194 5.40x41 NTS1 receptor 5T04 - -
TM5 195 5.41x42 NTS1 receptor 5T04 AT2 receptor 5UNG
TM5 196 5.42x43 NTS1 receptor 5T04 US28 4XT1
TM5 197 5.43x44 NTS1 receptor 5T04 LPA6 receptor 5XSZ
TM5 198 5.44x45 NTS1 receptor 5T04 Rhodopsin 5DYS
TM5 199 5.45x46 NTS1 receptor 5T04 AT2 receptor 5UNG
TM5 200 5.46x461 NTS1 receptor 5T04 AT2 receptor 5UNG
TM5 201 5.47x47 NTS1 receptor 5T04 - -
TM5 202 5.48x48 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM5 203 5.49x49 NTS1 receptor 5T04 PAF receptor 5ZKP
TM5 204 5.50x50 NTS1 receptor 5T04 NTS1 receptor 5T04
TM5 205 5.51x51 NTS1 receptor 5T04 PAF receptor 5ZKP
TM5 206 5.52x52 NTS1 receptor 5T04 NTS1 receptor 5T04
TM5 207 5.53x53 NTS1 receptor 5T04 LPA6 receptor 5XSZ
TM5 208 5.54x54 NTS1 receptor 5T04 5-HT1B receptor 6G79
TM5 209 5.55x55 NTS1 receptor 5T04 PAF receptor 5ZKP
TM5 210 5.56x56 NTS1 receptor 5T04 μ receptor 5C1M
TM5 211 5.57x57 NTS1 receptor 5T04 AT2 receptor 5UNG
TM5 212 5.58x58 NTS1 receptor 5T04 - -
TM5 213 5.59x59 NTS1 receptor 5T04 PAR1 3VW7
TM5 214 5.60x60 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM5 215 5.61x61 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM5 216 5.62x62 NTS1 receptor 5T04 - -
TM5 217 5.63x63 NTS1 receptor 5T04 A2A receptor 5IU4
TM5 218 5.64x64 NTS1 receptor 5T04 Rhodopsin 5DYS
TM5 219 5.65x65 NTS1 receptor 5T04 β2-adrenoceptor 3SN6
TM5 220 5.66x66 NTS1 receptor 5T04 - -
TM5 221 5.67x67 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM5 222 5.68x68 NTS1 receptor 5T04 AT2 receptor 5UNH
ICL3 223 - - - -
ICL3 224 AT2 receptor 5UNG - -
ICL3 225 - - - -
TM6 226 6.24x24 NTS1 receptor 5T04 A1 receptor 6D9H
TM6 227 6.25x25 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM6 228 6.26x26 NTS1 receptor 5T04 OX2 receptor 5WS3
TM6 229 6.27x27 NTS1 receptor 5T04 - -
TM6 230 6.28x28 NTS1 receptor 5T04 PAF receptor 5ZKP
TM6 231 6.29x29 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 232 6.30x30 NTS1 receptor 5T04 - -
TM6 233 6.31x31 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 234 6.32x32 NTS1 receptor 5T04 - -
TM6 235 6.33x33 NTS1 receptor 5T04 - -
TM6 236 6.34x34 NTS1 receptor 5T04 CB1 receptor 5XRA
TM6 237 6.35x35 NTS1 receptor 5T04 μ receptor 5C1M
TM6 238 6.36x36 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 239 6.37x37 NTS1 receptor 5T04 AT2 receptor 5UNG
TM6 240 6.38x38 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 241 6.39x39 NTS1 receptor 5T04 CCR9 5LWE
TM6 242 6.40x40 NTS1 receptor 5T04 M2 receptor 4MQT
TM6 243 6.41x41 NTS1 receptor 5T04 LPA6 receptor 5XSZ
TM6 244 6.42x42 NTS1 receptor 5T04 S1P1 receptor 3V2Y
TM6 245 6.43x43 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 246 6.44x44 NTS1 receptor 5T04 CCR2 5T1A
TM6 247 6.45x45 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 248 6.46x46 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 249 6.47x47 NTS1 receptor 5T04 - -
TM6 250 6.48x48 NTS1 receptor 5T04 - -
TM6 251 6.49x49 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 252 6.50x50 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 253 6.51x51 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 254 6.52x52 NTS1 receptor 5T04 C5a1 receptor 5O9H
TM6 255 6.53x53 NTS1 receptor 5T04 US28 4XT1
TM6 256 6.54x54 NTS1 receptor 5T04 P2Y12 receptor 4NTJ
TM6 257 6.55x55 NTS1 receptor 5T04 PAF receptor 5ZKP
TM6 258 6.56x56 NTS1 receptor 5T04 NTS1 receptor 5T04
TM6 259 6.57x57 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM6 260 6.58x58 NTS1 receptor 5T04 LPA6 receptor 5XSZ
TM6 261 6.59x59 NTS1 receptor 5T04 A1 receptor 6D9H
TM6 262 6.60x60 NTS1 receptor 5T04 - -
TM6 263 6.61x61 NTS1 receptor 5T04 OX1 receptor 4ZJ8
ECL3 264 - - - -
ECL3 265 - - - -
ECL3 266 - - - -
ECL3 267 - - - -
ECL3 268 - - - -
ECL3 269 - - - -
TM7 270 7.28x27 NTS1 receptor 5T04 - -
TM7 271 7.29x28 NTS1 receptor 5T04 - -
TM7 272 7.30x29 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM7 273 7.31x30 NTS1 receptor 5T04 5-HT2B receptor 5TUD
TM7 274 7.32x31 NTS1 receptor 5T04 - -
TM7 275 7.33x32 NTS1 receptor 5T04 β2-adrenoceptor 4LDE
TM7 276 7.34x33 NTS1 receptor 5T04 AT2 receptor 5UNG
TM7 277 7.35x34 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM7 278 7.36x35 NTS1 receptor 5T04 - -
TM7 279 7.37x36 NTS1 receptor 5T04 apelin receptor 5VBL
TM7 280 7.38x37 NTS1 receptor 5T04 OX2 receptor 5WS3
TM7 281 7.39x38 NTS1 receptor 5T04 - -
TM7 282 7.40x39 NTS1 receptor 5T04 - -
TM7 283 7.41x40 NTS1 receptor 5T04 NTS1 receptor 5T04
TM7 284 7.42x41 NTS1 receptor 5T04 - -
TM7 285 7.43x42 NTS1 receptor 5T04 CB1 receptor 5XRA
TM7 286 7.44x43 NTS1 receptor 5T04 CB1 receptor 5XRA
TM7 287 7.45x45 NTS1 receptor 5T04 5-HT2C receptor 6BQG
TM7 288 7.46x46 NTS1 receptor 5T04 NTS1 receptor 5T04
TM7 289 7.47x47 NTS1 receptor 5T04 AT2 receptor 5UNG
TM7 290 7.48x48 NTS1 receptor 5T04 μ receptor 5C1M
TM7 291 7.49x49 C5a1 receptor 5O9H - -
TM7 292 7.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 293 7.51x51 C5a1 receptor 5O9H AT2 receptor 5UNG
TM7 294 7.52x52 C5a1 receptor 5O9H AT2 receptor 5UNG
TM7 295 7.53x53 C5a1 receptor 5O9H - -
TM7 296 7.54x54 C5a1 receptor 5O9H - -
TM7 297 7.55x55 C5a1 receptor 5O9H Rhodopsin 5DYS
TM7 298 7.56x56 C5a1 receptor 5O9H C5a1 receptor 5O9H
H8 299 8.47x47 NTS1 receptor 4BUO NTS1 receptor 4BUO
H8 300 8.48x48 NTS1 receptor 4BUO NTS1 receptor 4BUO
H8 301 8.49x49 NTS1 receptor 4BUO β2-adrenoceptor 3SN6
H8 302 8.50x50 NTS1 receptor 4BUO CB1 receptor 5XRA
H8 303 8.51x51 NTS1 receptor 4BUO NTS1 receptor 4BUO
H8 304 8.52x52 NTS1 receptor 4BUO M3 receptor 4U15
H8 305 8.53x53 NTS1 receptor 4BUO - -
H8 306 8.54x54 NTS1 receptor 4BUO AT2 receptor 5UNG
H8 307 8.55x55 NTS1 receptor 4BUO CB1 receptor 5XRA
H8 308 8.56x56 NTS1 receptor 4BUO NTS1 receptor 4BUO
H8 309 8.57x57 NTS1 receptor 4BUO AT2 receptor 5UNG
H8 310 8.58x58 NTS1 receptor 4BUO NTS1 receptor 4BUO
C-term 311 - - - -
C-term 312 - - - -
C-term 313 - - - -
C-term 314 - - - -
C-term 315 - - - -