GPR160 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 7.54 docs)

VERSION

2018-07-10

MAIN TEMPLATE

Rhodopsin (sequence similarity: 29%) PDB: 5DYS

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 87.7 6.7 5.7
Side-chains 16.7 43.7 39.7

Number of backbone templates: 6
Number of rotamer templates: 35

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5DYS
4NTJ
4PXZ
3UON
4YAY
3SN6
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 12 Rhodopsin 5DYS Rhodopsin 5DYS
N-term 13 Rhodopsin 5DYS Rhodopsin 5DYS
N-term 14 Rhodopsin 5DYS Rhodopsin 5DYS
N-term 15 Rhodopsin 5DYS Rhodopsin 5DYS
N-term 16 Rhodopsin 5DYS Rhodopsin 5DYS
TM1 17 1.28x28 Rhodopsin 5DYS - -
TM1 18 1.29x29 Rhodopsin 5DYS M2 receptor 4MQT
TM1 19 1.30x30 Rhodopsin 5DYS - -
TM1 20 1.31x31 Rhodopsin 5DYS Rhodopsin 5DYS
TM1 21 1.32x32 Rhodopsin 5DYS κ receptor 6B73
TM1 22 1.33x33 Rhodopsin 5DYS CB1 receptor 5XRA
TM1 23 1.34x34 Rhodopsin 5DYS - -
TM1 24 1.35x35 Rhodopsin 5DYS NTS1 receptor 5T04
TM1 25 1.36x36 Rhodopsin 5DYS - -
TM1 26 1.37x37 Rhodopsin 5DYS - -
TM1 27 1.38x38 Rhodopsin 5DYS 5-HT2B receptor 5TUD
TM1 28 1.39x39 Rhodopsin 5DYS 5-HT2B receptor 5TUD
TM1 29 1.40x40 Rhodopsin 5DYS Rhodopsin 5DYS
TM1 30 1.41x41 Rhodopsin 5DYS Rhodopsin 5DYS
TM1 31 1.42x42 Rhodopsin 5DYS PAF receptor 5ZKP
TM1 32 1.43x43 Rhodopsin 5DYS Rhodopsin 5DYS
TM1 33 1.44x44 Rhodopsin 5DYS M2 receptor 4MQT
TM1 34 1.45x45 Rhodopsin 5DYS NOP receptor 5DHG
TM1 35 1.46x46 Rhodopsin 5DYS - -
TM1 36 1.47x47 Rhodopsin 5DYS M2 receptor 4MQT
TM1 37 1.48x48 Rhodopsin 5DYS AT2 receptor 5UNG
TM1 38 1.49x49 Rhodopsin 5DYS PAR1 3VW7
TM1 39 1.50x50 Rhodopsin 5DYS Rhodopsin 5DYS
TM1 40 1.51x51 Rhodopsin 5DYS M2 receptor 4MQT
TM1 41 1.52x52 Rhodopsin 5DYS Rhodopsin 5DYS
TM1 42 1.53x53 Rhodopsin 5DYS Rhodopsin 5DYS
TM1 43 1.54x54 Rhodopsin 5DYS Rhodopsin 5DYS
TM1 44 1.55x55 Rhodopsin 5DYS - -
TM1 45 1.56x56 Rhodopsin 5DYS P2Y1 receptor 4XNW
TM1 46 1.57x57 Rhodopsin 5DYS - -
TM1 47 1.58x58 Rhodopsin 5DYS H1 receptor 3RZE
TM1 48 1.59x59 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM1 49 1.60x60 Rhodopsin 5DYS M2 receptor 4MQT
ICL1 50 - - - -
ICL1 51 P2Y12 receptor 4NTJ - -
ICL1 52 - - - -
TM2 53 2.37x37 Rhodopsin 5DYS LPA6 receptor 5XSZ
TM2 54 2.38x38 Rhodopsin 5DYS - -
TM2 55 2.39x39 Rhodopsin 5DYS S1P1 receptor 3V2Y
TM2 56 2.40x40 Rhodopsin 5DYS - -
TM2 57 2.41x41 Rhodopsin 5DYS Rhodopsin 5DYS
TM2 58 2.42x42 Rhodopsin 5DYS M2 receptor 4MQT
TM2 59 2.43x43 Rhodopsin 5DYS - -
TM2 60 2.44x44 Rhodopsin 5DYS US28 4XT1
TM2 61 2.45x45 Rhodopsin 5DYS M2 receptor 4MQT
TM2 62 2.46x46 Rhodopsin 5DYS Rhodopsin 5DYS
TM2 63 2.47x47 Rhodopsin 5DYS Rhodopsin 5DYS
TM2 64 2.48x48 Rhodopsin 5DYS Y1 receptor 5ZBH
TM2 65 2.49x49 Rhodopsin 5DYS - -
TM2 66 2.50x50 Rhodopsin 5DYS Rhodopsin 5DYS
TM2 67 2.51x51 Rhodopsin 5DYS Rhodopsin 5DYS
TM2 68 2.52x52 Rhodopsin 5DYS PAF receptor 5ZKP
TM2 69 2.53x53 Rhodopsin 5DYS AT2 receptor 5UNG
TM2 70 2.54x54 Rhodopsin 5DYS PAF receptor 5ZKP
TM2 71 2.55x55 P2Y12 receptor 4NTJ M2 receptor 4MQT
TM2 72 2.56x56 P2Y12 receptor 4NTJ - -
TM2 73 2.57x57 Rhodopsin 5DYS A1 receptor 6D9H
TM2 74 2.58x58 Rhodopsin 5DYS - -
TM2 75 2.59x59 Rhodopsin 5DYS 5-HT2B receptor 5TUD
TM2 76 2.60x60 Rhodopsin 5DYS Rhodopsin 5DYS
TM2 77 2.61x61 Rhodopsin 5DYS Rhodopsin 5DYS
TM2 78 2.62x62 Rhodopsin 5DYS Rhodopsin 5DYS
TM2 79 2.63x63 Rhodopsin 5DYS BLT1 receptor 5X33
TM2 80 2.64x64 Rhodopsin 5DYS - -
TM2 81 2.65x65 Rhodopsin 5DYS - -
TM2 82 2.66x66 Rhodopsin 5DYS 5-HT2B receptor 4NC3
ECL1 83 Rhodopsin 5DYS - -
ECL1 84 Rhodopsin 5DYS Rhodopsin 5DYS
ECL1 85 Rhodopsin 5DYS Rhodopsin 5DYS
ECL1 86 Rhodopsin 5DYS Rhodopsin 5DYS
ECL1 87 Rhodopsin 5DYS Rhodopsin 5DYS
TM3 88 3.18x18 P2Y12 receptor 4PXZ - -
TM3 89 3.19x19 P2Y12 receptor 4PXZ - -
TM3 90 3.20x20 P2Y12 receptor 4PXZ - -
TM3 91 3.21x21 Rhodopsin 5DYS - -
TM3 92 3.22x22 Rhodopsin 5DYS - -
TM3 93 3.23x23 Rhodopsin 5DYS A1 receptor 6D9H
TM3 94 3.24x24 Rhodopsin 5DYS - -
TM3 95 3.25x25 Rhodopsin 5DYS Rhodopsin 5DYS
TM3 96 3.26x26 Rhodopsin 5DYS A1 receptor 6D9H
TM3 97 3.27x27 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM3 98 3.28x28 Rhodopsin 5DYS P2Y12 receptor 4NTJ
TM3 99 3.29x29 Rhodopsin 5DYS LPA1 receptor 4Z35
TM3 100 3.30x30 Rhodopsin 5DYS - -
TM3 101 3.31x31 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM3 102 3.32x32 Rhodopsin 5DYS - -
TM3 103 3.33x33 Rhodopsin 5DYS PAF receptor 5ZKP
TM3 104 3.34x34 Rhodopsin 5DYS LPA6 receptor 5XSZ
TM3 105 3.35x35 Rhodopsin 5DYS - -
TM3 106 3.36x36 Rhodopsin 5DYS Rhodopsin 5DYS
TM3 107 3.37x37 Rhodopsin 5DYS AT2 receptor 5UNG
TM3 108 3.38x38 Rhodopsin 5DYS - -
TM3 109 3.39x39 Rhodopsin 5DYS - -
TM3 110 3.40x40 Rhodopsin 5DYS - -
TM3 111 3.41x41 Rhodopsin 5DYS - -
TM3 112 3.42x42 Rhodopsin 5DYS - -
TM3 113 3.43x43 Rhodopsin 5DYS - -
TM3 114 3.44x44 Rhodopsin 5DYS M2 receptor 4MQT
TM3 115 3.45x45 Rhodopsin 5DYS μ receptor 5C1M
TM3 116 3.46x46 Rhodopsin 5DYS CB1 receptor 5XRA
TM3 117 3.47x47 Rhodopsin 5DYS H1 receptor 3RZE
TM3 118 3.48x48 Rhodopsin 5DYS Rhodopsin 5DYS
TM3 119 3.49x49 Rhodopsin 5DYS M2 receptor 4MQT
TM3 120 3.50x50 Rhodopsin 5DYS - -
TM3 121 3.51x51 Rhodopsin 5DYS - -
TM3 122 3.52x52 Rhodopsin 5DYS LPA6 receptor 5XSZ
TM3 123 3.53x53 Rhodopsin 5DYS - -
TM3 124 3.54x54 Rhodopsin 5DYS - -
TM3 125 3.55x55 Rhodopsin 5DYS - -
TM3 126 3.56x56 Rhodopsin 5DYS Rhodopsin 5DYS
ICL2 127 - - - -
ICL2 128 M2 receptor 3UON - -
ICL2 129 M2 receptor 3UON - -
ICL2 130 M2 receptor 3UON - -
ICL2 131 M2 receptor 3UON - -
ICL2 132 M2 receptor 3UON - -
ICL2 133 M2 receptor 3UON M2 receptor 3UON
ICL2 134 - - - -
TM4 135 4.38x38 Rhodopsin 5DYS - -
TM4 136 4.39x39 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM4 137 4.40x40 Rhodopsin 5DYS κ receptor 6B73
TM4 138 4.41x41 Rhodopsin 5DYS CCR5 5UIW
TM4 139 4.42x42 Rhodopsin 5DYS - -
TM4 140 4.43x43 Rhodopsin 5DYS 5-HT2B receptor 5TUD
TM4 141 4.44x44 Rhodopsin 5DYS PAR1 3VW7
TM4 142 4.45x45 Rhodopsin 5DYS PAR1 3VW7
TM4 143 4.46x46 Rhodopsin 5DYS Rhodopsin 5DYS
TM4 144 4.47x47 Rhodopsin 5DYS US28 4XT1
TM4 145 4.48x48 Rhodopsin 5DYS 5-HT1B receptor 6G79
TM4 146 4.49x49 Rhodopsin 5DYS PAF receptor 5ZKP
TM4 147 4.50x50 Rhodopsin 5DYS Rhodopsin 5DYS
TM4 148 4.51x51 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM4 149 4.52x52 Rhodopsin 5DYS - -
TM4 150 4.53x53 Rhodopsin 5DYS LPA6 receptor 5XSZ
TM4 151 4.54x54 Rhodopsin 5DYS Rhodopsin 5DYS
TM4 152 4.55x55 Rhodopsin 5DYS Rhodopsin 5DYS
TM4 153 4.56x56 Rhodopsin 5DYS - -
TM4 154 4.57x57 Rhodopsin 5DYS PAR1 3VW7
TM4 155 4.58x58 Rhodopsin 5DYS LPA6 receptor 5XSZ
TM4 156 4.59x59 Rhodopsin 5DYS - -
TM4 157 4.60x60 Rhodopsin 5DYS - -
TM4 158 4.61x61 Rhodopsin 5DYS - -
TM4 159 4.62x62 Rhodopsin 5DYS Rhodopsin 4ZWJ
TM4 160 4.63x63 P2Y12 receptor 4PXZ 5-HT2B receptor 5TUD
ECL2 161 Rhodopsin 5DYS - -
ECL2 162 Rhodopsin 5DYS - -
ECL2 163 Rhodopsin 5DYS Rhodopsin 5DYS
ECL2 164 Rhodopsin 5DYS - -
ECL2 165 Rhodopsin 5DYS - -
ECL2 166 Rhodopsin 5DYS - -
ECL2 167 Rhodopsin 5DYS - -
ECL2 168 Rhodopsin 5DYS - -
ECL2 169 Rhodopsin 5DYS - -
ECL2 170 Rhodopsin 5DYS - -
ECL2 171 Rhodopsin 5DYS - -
ECL2 172 Rhodopsin 5DYS - -
ECL2 173 Rhodopsin 5DYS - -
ECL2 174 45.50x50 Rhodopsin 5DYS Rhodopsin 5DYS
ECL2 175 45.51x51 Rhodopsin 5DYS - -
ECL2 176 45.52x52 Rhodopsin 5DYS β2-adrenoceptor 4LDE
ECL2 177 - - - -
ECL2 178 AT1 receptor 4YAY - -
ECL2 179 AT1 receptor 4YAY - -
ECL2 180 - - - -
TM5 181 5.35x35 Rhodopsin 5DYS - -
TM5 182 5.36x36 Rhodopsin 5DYS AT2 receptor 5UNG
TM5 183 5.37x37 Rhodopsin 5DYS PAR1 3VW7
TM5 184 5.38x38 Rhodopsin 5DYS H1 receptor 3RZE
TM5 185 5.39x39 Rhodopsin 5DYS US28 4XT1
TM5 186 5.40x40 Rhodopsin 5DYS PAR1 3VW7
TM5 187 5.41x41 Rhodopsin 5DYS M2 receptor 4MQT
TM5 188 5.42x42 Rhodopsin 5DYS PAF receptor 5ZKP
TM5 189 5.43x43 Rhodopsin 5DYS Rhodopsin 5DYS
TM5 190 5.44x44 Rhodopsin 5DYS PAF receptor 5ZKP
TM5 191 5.45x45 Rhodopsin 5DYS M1 receptor 5CXV
TM5 192 5.46x46 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
TM5 193 5.47x47 P2Y12 receptor 4NTJ CCR5 5UIW
TM5 194 5.48x48 Rhodopsin 5DYS PAF receptor 5ZKP
TM5 195 5.49x49 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM5 196 5.50x50 Rhodopsin 5DYS - -
TM5 197 5.51x51 Rhodopsin 5DYS PAF receptor 5ZKP
TM5 198 5.52x52 Rhodopsin 5DYS Rhodopsin 5DYS
TM5 199 5.53x53 Rhodopsin 5DYS C5a1 receptor 5O9H
TM5 200 5.54x54 Rhodopsin 5DYS - -
TM5 201 5.55x55 Rhodopsin 5DYS - -
TM5 202 5.56x56 Rhodopsin 5DYS - -
TM5 203 5.57x57 Rhodopsin 5DYS - -
TM5 204 5.58x58 Rhodopsin 5DYS - -
TM5 205 5.59x59 Rhodopsin 5DYS NTS1 receptor 5T04
TM5 206 5.60x60 Rhodopsin 5DYS - -
TM5 207 5.61x61 Rhodopsin 5DYS Rhodopsin 5DYS
TM5 208 5.62x62 Rhodopsin 5DYS Rhodopsin 5DYS
TM5 209 5.63x63 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM5 210 5.64x64 Rhodopsin 5DYS M2 receptor 4MQT
TM5 211 5.65x65 Rhodopsin 5DYS A1 receptor 6D9H
TM5 212 5.66x66 Rhodopsin 5DYS 5-HT1B receptor 6G79
TM5 213 5.67x67 Rhodopsin 5DYS - -
TM5 214 5.68x68 Rhodopsin 5DYS AT2 receptor 5UNH
TM5 215 5.69x69 Rhodopsin 5DYS - -
TM5 216 5.70x70 Rhodopsin 5DYS - -
TM5 217 5.71x71 Rhodopsin 5DYS - -
TM5 218 5.72x72 Rhodopsin 5DYS - -
TM5 219 5.73x73 β2-adrenoceptor 3SN6 A2A receptor 4UHR
ICL3 220 - - - -
ICL3 221 - - - -
ICL3 222 - - - -
ICL3 223 - - - -
ICL3 224 - - - -
ICL3 225 - - - -
ICL3 226 - - - -
ICL3 227 - - - -
TM6 228 6.24x24 Rhodopsin 5DYS - -
TM6 229 6.25x25 Rhodopsin 5DYS - -
TM6 230 6.26x26 Rhodopsin 5DYS - -
TM6 231 6.27x27 Rhodopsin 5DYS PAR2 5NDD
TM6 232 6.28x28 Rhodopsin 5DYS - -
TM6 233 6.29x29 Rhodopsin 5DYS AT2 receptor 5UNG
TM6 234 6.30x30 Rhodopsin 5DYS PAF receptor 5ZKP
TM6 235 6.31x31 Rhodopsin 5DYS NTS1 receptor 5T04
TM6 236 6.32x32 Rhodopsin 5DYS PAR1 3VW7
TM6 237 6.33x33 Rhodopsin 5DYS P2Y1 receptor 4XNW
TM6 238 6.34x34 Rhodopsin 5DYS - -
TM6 239 6.35x35 Rhodopsin 5DYS P2Y1 receptor 4XNW
TM6 240 6.36x36 Rhodopsin 5DYS PAR1 3VW7
TM6 241 6.37x37 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM6 242 6.38x38 Rhodopsin 5DYS PAR1 3VW7
TM6 243 6.39x39 Rhodopsin 5DYS - -
TM6 244 6.40x40 Rhodopsin 5DYS ETB receptor 5X93
TM6 245 6.41x41 Rhodopsin 5DYS P2Y12 receptor 4NTJ
TM6 246 6.42x42 Rhodopsin 5DYS CB1 receptor 5XRA
TM6 247 6.43x43 Rhodopsin 5DYS PAR1 3VW7
TM6 248 6.44x44 Rhodopsin 5DYS Rhodopsin 5DYS
TM6 249 6.45x45 Rhodopsin 5DYS Rhodopsin 5DYS
TM6 250 6.46x46 Rhodopsin 5DYS - -
TM6 251 6.47x47 Rhodopsin 5DYS M2 receptor 4MQT
TM6 252 6.48x48 Rhodopsin 5DYS Rhodopsin 5DYS
TM6 253 6.49x49 Rhodopsin 5DYS Rhodopsin 5DYS
TM6 254 6.50x50 Rhodopsin 5DYS Rhodopsin 5DYS
TM6 255 6.51x51 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM6 256 6.52x52 Rhodopsin 5DYS - -
TM6 257 6.53x53 Rhodopsin 5DYS US28 4XT1
TM6 258 6.54x54 Rhodopsin 5DYS AT2 receptor 5UNG
TM6 259 6.55x55 Rhodopsin 5DYS PAF receptor 5ZKP
TM6 260 6.56x56 Rhodopsin 5DYS LPA6 receptor 5XSZ
TM6 261 6.57x57 Rhodopsin 5DYS M2 receptor 4MQT
TM6 262 6.58x58 Rhodopsin 5DYS Rhodopsin 5DYS
TM6 263 6.59x59 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM6 264 6.60x60 Rhodopsin 5DYS PAF receptor 5ZKP
TM6 265 6.61x61 Rhodopsin 5DYS PAR2 5NDD
ECL3 266 - - - -
ECL3 267 M2 receptor 3UON - -
ECL3 268 M2 receptor 3UON - -
ECL3 269 - - - -
TM7 270 7.31x30 Rhodopsin 5DYS M2 receptor 4MQT
TM7 271 7.32x31 Rhodopsin 5DYS FFA1 receptor 5KW2
TM7 272 7.33x32 Rhodopsin 5DYS NTS1 receptor 5T04
TM7 273 7.34x33 Rhodopsin 5DYS LPA6 receptor 5XSZ
TM7 274 7.35x34 Rhodopsin 5DYS LPA1 receptor 4Z35
TM7 275 7.36x35 Rhodopsin 5DYS NTS1 receptor 5T04
TM7 276 7.37x36 Rhodopsin 5DYS - -
TM7 277 7.38x37 Rhodopsin 5DYS - -
TM7 278 7.39x38 Rhodopsin 5DYS - -
TM7 279 7.40x39 Rhodopsin 5DYS M2 receptor 4MQT
TM7 280 7.41x40 Rhodopsin 5DYS M2 receptor 4MQT
TM7 281 7.42x41 Rhodopsin 5DYS - -
TM7 282 7.43x42 Rhodopsin 5DYS AT2 receptor 5UNG
TM7 283 7.44x43 Rhodopsin 5DYS β2-adrenoceptor 3SN6
TM7 284 7.45x45 Rhodopsin 5DYS M2 receptor 4MQT
TM7 285 7.46x46 Rhodopsin 5DYS M2 receptor 4MQT
TM7 286 7.47x47 Rhodopsin 5DYS - -
TM7 287 7.48x48 Rhodopsin 5DYS PAF receptor 5ZKP
TM7 288 7.49x49 Rhodopsin 5DYS - -
TM7 289 7.50x50 Rhodopsin 5DYS - -
TM7 290 7.51x51 Rhodopsin 5DYS - -
TM7 291 7.52x52 Rhodopsin 5DYS 5-HT2B receptor 5TUD
TM7 292 7.53x53 Rhodopsin 5DYS Rhodopsin 5DYS
TM7 293 7.54x54 Rhodopsin 5DYS - -
TM7 294 7.55x55 Rhodopsin 5DYS PAF receptor 5ZKP
TM7 295 7.56x56 Rhodopsin 5DYS - -
H8 296 8.47x47 Rhodopsin 5DYS P2Y12 receptor 4NTJ
H8 297 8.48x48 Rhodopsin 5DYS PAR2 5NDD
H8 298 8.49x49 Rhodopsin 5DYS A1 receptor 6D9H
H8 299 8.50x50 Rhodopsin 5DYS CB1 receptor 5XRA
H8 300 8.51x51 Rhodopsin 5DYS - -
H8 301 8.52x52 Rhodopsin 5DYS - -
H8 302 8.53x53 Rhodopsin 5DYS AT2 receptor 5UNG
H8 303 8.54x54 Rhodopsin 5DYS - -
H8 304 8.55x55 Rhodopsin 5DYS S1P1 receptor 3V2Y
H8 305 8.56x56 Rhodopsin 5DYS - -
H8 306 8.57x57 Rhodopsin 5DYS M2 receptor 4MQT
C-term 307 Rhodopsin 5DYS Rhodopsin 5DYS
C-term 308 Rhodopsin 5DYS Rhodopsin 5DYS
C-term 309 Rhodopsin 5DYS Rhodopsin 5DYS
C-term 310 Rhodopsin 5DYS Rhodopsin 5DYS
C-term 311 - - - -