GPR162 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): -1.83 docs)

VERSION

2018-07-10

MAIN TEMPLATE

D2 receptor (sequence similarity: 35%) PDB: 6CM4

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 74.1 15.7 10.2
Side-chains 10.5 50.8 38.7

Number of backbone templates: 10
Number of rotamer templates: 36

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5ZBH
6CM4
5UNG
3PBL
3UON
4XNW
5WS3
3V2Y
3SN6
6D9H
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 4 Y1 receptor 5ZBH Y1 receptor 5ZBH
N-term 5 Y1 receptor 5ZBH Y1 receptor 5ZBH
N-term 6 Y1 receptor 5ZBH Y1 receptor 5ZBH
N-term 7 Y1 receptor 5ZBH Y1 receptor 5ZBH
N-term 8 Y1 receptor 5ZBH Y1 receptor 5ZBH
TM1 9 1.28x28 Y1 receptor 5ZBH Rhodopsin 1GZM
TM1 10 1.29x29 Y1 receptor 5ZBH β2-adrenoceptor 2RH1
TM1 11 1.30x30 Y1 receptor 5ZBH Y1 receptor 5ZBH
TM1 12 1.31x31 Y1 receptor 5ZBH NTS1 receptor 4BUO
TM1 13 1.32x32 Y1 receptor 5ZBH - -
TM1 14 1.33x33 D2 receptor 6CM4 - -
TM1 15 1.34x34 D2 receptor 6CM4 - -
TM1 16 1.35x35 D2 receptor 6CM4 ETB receptor 5X93
TM1 17 1.36x36 D2 receptor 6CM4 D2 receptor 6CM4
TM1 18 1.37x37 D2 receptor 6CM4 Y1 receptor 5ZBH
TM1 19 1.38x38 D2 receptor 6CM4 D3 receptor 3PBL
TM1 20 1.39x39 D2 receptor 6CM4 - -
TM1 21 1.40x40 D2 receptor 6CM4 A2A receptor 3VG9
TM1 22 1.41x41 D2 receptor 6CM4 Y1 receptor 5ZBH
TM1 23 1.42x42 D2 receptor 6CM4 - -
TM1 24 1.43x43 D2 receptor 6CM4 CB1 receptor 5TGZ
TM1 25 1.44x44 D2 receptor 6CM4 D3 receptor 3PBL
TM1 26 1.45x45 D2 receptor 6CM4 Y1 receptor 5ZBH
TM1 27 1.46x46 D2 receptor 6CM4 OX2 receptor 5WS3
TM1 28 1.47x47 D2 receptor 6CM4 OX2 receptor 5WS3
TM1 29 1.48x48 D2 receptor 6CM4 A2A receptor 3VG9
TM1 30 1.49x49 D2 receptor 6CM4 LPA1 receptor 4Z35
TM1 31 1.50x50 D2 receptor 6CM4 D2 receptor 6CM4
TM1 32 1.51x51 D2 receptor 6CM4 C5a1 receptor 5O9H
TM1 33 1.52x52 D2 receptor 6CM4 - -
TM1 34 1.53x53 D2 receptor 6CM4 - -
TM1 35 1.54x54 D2 receptor 6CM4 Y1 receptor 5ZBH
TM1 36 1.55x55 D2 receptor 6CM4 M4 receptor 5DSG
TM1 37 1.56x56 D2 receptor 6CM4 M2 receptor 3UON
TM1 38 1.57x57 D2 receptor 6CM4 Y1 receptor 5ZBH
TM1 39 1.58x58 D2 receptor 6CM4 D2 receptor 6CM4
TM1 40 1.59x59 D2 receptor 6CM4 FFA1 receptor 5TZY
TM1 41 1.60x60 D2 receptor 6CM4 - -
ICL1 42 12.48x48 D2 receptor 6CM4 A1 receptor 5UEN
ICL1 43 12.49x49 D2 receptor 6CM4 M4 receptor 5DSG
ICL1 44 12.50x50 D2 receptor 6CM4 - -
ICL1 45 12.51x51 D2 receptor 6CM4 5-HT2C receptor 6BQH
TM2 46 2.38x38 D2 receptor 6CM4 - -
TM2 47 2.39x39 D2 receptor 6CM4 ETB receptor 5X93
TM2 48 2.40x40 D2 receptor 6CM4 - -
TM2 49 2.41x41 D2 receptor 6CM4 - -
TM2 50 2.42x42 D2 receptor 6CM4 D2 receptor 6CM4
TM2 51 2.43x43 D2 receptor 6CM4 5-HT2C receptor 6BQH
TM2 52 2.44x44 D2 receptor 6CM4 M3 receptor 4U15
TM2 53 2.45x45 D2 receptor 6CM4 - -
TM2 54 2.46x46 D2 receptor 6CM4 - -
TM2 55 2.47x47 D2 receptor 6CM4 - -
TM2 56 2.48x48 D2 receptor 6CM4 D4 receptor 5WIV
TM2 57 2.49x49 D2 receptor 6CM4 ETB receptor 5X93
TM2 58 2.50x50 D2 receptor 6CM4 - -
TM2 59 2.51x51 D2 receptor 6CM4 - -
TM2 60 2.52x52 D2 receptor 6CM4 M2 receptor 3UON
TM2 61 2.53x53 D2 receptor 6CM4 D4 receptor 5WIV
TM2 62 2.54x54 D2 receptor 6CM4 - -
TM2 63 2.55x55 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 64 2.56x56 AT2 receptor 5UNG A2A receptor 3VG9
TM2 65 2.57x57 D2 receptor 6CM4 β2-adrenoceptor 5JQH
TM2 66 2.58x58 D2 receptor 6CM4 D2 receptor 6CM4
TM2 67 2.59x59 D2 receptor 6CM4 5-HT2C receptor 6BQH
TM2 68 2.60x60 D2 receptor 6CM4 Y1 receptor 5ZBH
TM2 69 2.61x61 D2 receptor 6CM4 M2 receptor 3UON
TM2 70 2.62x62 D2 receptor 6CM4 LPA1 receptor 4Z35
TM2 71 2.63x63 D2 receptor 6CM4 5-HT2C receptor 6BQH
TM2 72 2.64x64 D2 receptor 6CM4 - -
TM2 73 2.65x65 D2 receptor 6CM4 D3 receptor 3PBL
TM2 74 2.66x66 D2 receptor 6CM4 D4 receptor 5WIV
TM2 75 2.67x67 D2 receptor 6CM4 - -
TM2 76 2.68x68 - - - -
ECL1 77 - - - -
ECL1 78 - - - -
ECL1 79 - - - -
ECL1 80 - - - -
ECL1 81 - - - -
ECL1 82 23.49x49 - - - -
ECL1 83 23.50x50 - - - -
ECL1 84 23.51x51 - - - -
ECL1 85 23.52x52 - - - -
TM3 86 3.21x21 D2 receptor 6CM4 - -
TM3 87 3.22x22 D2 receptor 6CM4 Y1 receptor 5ZBH
TM3 88 3.23x23 D2 receptor 6CM4 OX2 receptor 5WS3
TM3 89 3.24x24 D2 receptor 6CM4 - -
TM3 90 3.25x25 D2 receptor 6CM4 D2 receptor 6CM4
TM3 91 3.26x26 D2 receptor 6CM4 Y1 receptor 5ZBH
TM3 92 3.27x27 D2 receptor 6CM4 5-HT2C receptor 6BQH
TM3 93 3.28x28 D2 receptor 6CM4 D2 receptor 6CM4
TM3 94 3.29x29 D2 receptor 6CM4 D2 receptor 6CM4
TM3 95 3.30x30 D2 receptor 6CM4 5-HT2C receptor 6BQH
TM3 96 3.31x31 D2 receptor 6CM4 - -
TM3 97 3.32x32 D2 receptor 6CM4 CCR5 5UIW
TM3 98 3.33x33 D2 receptor 6CM4 M2 receptor 3UON
TM3 99 3.34x34 D2 receptor 6CM4 LPA1 receptor 4Z35
TM3 100 3.35x35 D2 receptor 6CM4 A1 receptor 5UEN
TM3 101 3.36x36 D2 receptor 6CM4 A1 receptor 5N2S
TM3 102 3.37x37 D2 receptor 6CM4 - -
TM3 103 3.38x38 D2 receptor 6CM4 D2 receptor 6CM4
TM3 104 3.39x39 D2 receptor 6CM4 NTS1 receptor 4BUO
TM3 105 3.40x40 D2 receptor 6CM4 - -
TM3 106 3.41x41 D2 receptor 6CM4 H1 receptor 3RZE
TM3 107 3.42x42 D2 receptor 6CM4 OX2 receptor 5WS3
TM3 108 3.43x43 D2 receptor 6CM4 H1 receptor 3RZE
TM3 109 3.44x44 D2 receptor 6CM4 C5a1 receptor 5O9H
TM3 110 3.45x45 D2 receptor 6CM4 NTS1 receptor 4BUO
TM3 111 3.46x46 D2 receptor 6CM4 H1 receptor 3RZE
TM3 112 3.47x47 D2 receptor 6CM4 D2 receptor 6CM4
TM3 113 3.48x48 D2 receptor 6CM4 PAF receptor 5ZKP
TM3 114 3.49x49 D2 receptor 6CM4 P2Y1 receptor 4XNW
TM3 115 3.50x50 D2 receptor 6CM4 D2 receptor 6CM4
TM3 116 3.51x51 D2 receptor 6CM4 - -
TM3 117 3.52x52 D2 receptor 6CM4 5-HT1B receptor 4IAQ
TM3 118 3.53x53 D2 receptor 6CM4 - -
TM3 119 3.54x54 D2 receptor 6CM4 D2 receptor 6CM4
TM3 120 3.55x55 D2 receptor 6CM4 A2A receptor 3VG9
TM3 121 3.56x56 D2 receptor 6CM4 - -
ICL2 122 34.50x50 - - - -
ICL2 123 34.51x51 D3 receptor 3PBL D3 receptor 3PBL
ICL2 124 34.52x52 D3 receptor 3PBL - -
ICL2 125 34.53x53 D3 receptor 3PBL D3 receptor 3PBL
ICL2 126 34.54x54 D3 receptor 3PBL M3 receptor 4U15
ICL2 127 34.55x55 D3 receptor 3PBL - -
ICL2 128 34.56x56 D3 receptor 3PBL - -
ICL2 129 34.57x57 - - - -
TM4 130 4.38x38 D2 receptor 6CM4 - -
TM4 131 4.39x39 D2 receptor 6CM4 H1 receptor 3RZE
TM4 132 4.40x40 D2 receptor 6CM4 M2 receptor 3UON
TM4 133 4.41x41 D2 receptor 6CM4 AT2 receptor 5UNG
TM4 134 4.42x42 D2 receptor 6CM4 Y1 receptor 5ZBH
TM4 135 4.43x43 D2 receptor 6CM4 D4 receptor 5WIV
TM4 136 4.44x44 D2 receptor 6CM4 - -
TM4 137 4.45x45 D2 receptor 6CM4 A1 receptor 5UEN
TM4 138 4.46x46 D2 receptor 6CM4 Rhodopsin 1GZM
TM4 139 4.47x47 D2 receptor 6CM4 - -
TM4 140 4.48x48 D2 receptor 6CM4 A1 receptor 5UEN
TM4 141 4.49x49 D2 receptor 6CM4 Y1 receptor 5ZBH
TM4 142 4.50x50 D2 receptor 6CM4 D2 receptor 6CM4
TM4 143 4.51x51 D2 receptor 6CM4 - -
TM4 144 4.52x52 D2 receptor 6CM4 OX2 receptor 5WS3
TM4 145 4.53x53 D2 receptor 6CM4 D2 receptor 6CM4
TM4 146 4.54x54 D2 receptor 6CM4 D2 receptor 6CM4
TM4 147 4.55x55 D2 receptor 6CM4 M2 receptor 3UON
TM4 148 4.56x56 D2 receptor 6CM4 M2 receptor 3UON
TM4 149 4.57x57 M2 receptor 3UON M2 receptor 3UON
TM4 150 4.58x58 M2 receptor 3UON - -
TM4 151 4.59x59 M2 receptor 3UON Y1 receptor 5ZBH
TM4 152 4.60x60 D2 receptor 6CM4 D2 receptor 6CM4
TM4 153 4.61x61 D2 receptor 6CM4 LPA1 receptor 4Z35
TM4 154 4.62x62 D2 receptor 6CM4 AT1 receptor 4ZUD
TM4 155 4.63x63 D2 receptor 6CM4 A1 receptor 5UEN
TM4 156 4.64x64 Y1 receptor 5ZBH M2 receptor 3UON
ECL2 157 - - - -
ECL2 158 P2Y1 receptor 4XNW - -
ECL2 159 P2Y1 receptor 4XNW - -
ECL2 160 P2Y1 receptor 4XNW - -
ECL2 161 P2Y1 receptor 4XNW - -
ECL2 162 P2Y1 receptor 4XNW - -
ECL2 163 P2Y1 receptor 4XNW - -
ECL2 164 P2Y1 receptor 4XNW - -
ECL2 165 P2Y1 receptor 4XNW - -
ECL2 166 P2Y1 receptor 4XNW - -
ECL2 167 - - - -
ECL2 168 45.50x50 D2 receptor 6CM4 D2 receptor 6CM4
ECL2 169 45.51x51 D2 receptor 6CM4 - -
ECL2 170 45.52x52 D2 receptor 6CM4 A1 receptor 5UEN
ECL2 171 - - - -
ECL2 172 OX2 receptor 5WS3 - -
ECL2 173 OX2 receptor 5WS3 - -
ECL2 174 OX2 receptor 5WS3 - -
ECL2 175 - - - -
TM5 176 5.35x35 Y1 receptor 5ZBH - -
TM5 177 5.36x36 Y1 receptor 5ZBH NTS1 receptor 4BUO
TM5 178 5.37x37 Y1 receptor 5ZBH 5-HT2B receptor 4IB4
TM5 179 5.38x38 D2 receptor 6CM4 CCR5 5UIW
TM5 180 5.39x39 D2 receptor 6CM4 - -
TM5 181 5.40x40 D2 receptor 6CM4 D2 receptor 6CM4
TM5 182 5.41x41 D2 receptor 6CM4 - -
TM5 183 5.42x42 D2 receptor 6CM4 A1 receptor 5UEN
TM5 184 5.43x43 D2 receptor 6CM4 D2 receptor 6CM4
TM5 185 5.44x44 D2 receptor 6CM4 Y1 receptor 5ZBH
TM5 186 5.45x45 D2 receptor 6CM4 OX2 receptor 5WS3
TM5 187 5.46x46 S1P1 receptor 3V2Y Y1 receptor 5ZBH
TM5 188 5.47x47 S1P1 receptor 3V2Y CCR5 5UIW
TM5 189 5.48x48 D2 receptor 6CM4 - -
TM5 190 5.49x49 D2 receptor 6CM4 Y1 receptor 5ZBH
TM5 191 5.50x50 D2 receptor 6CM4 - -
TM5 192 5.51x51 D2 receptor 6CM4 M2 receptor 3UON
TM5 193 5.52x52 D2 receptor 6CM4 - -
TM5 194 5.53x53 D2 receptor 6CM4 - -
TM5 195 5.54x54 D2 receptor 6CM4 C5a1 receptor 5O9H
TM5 196 5.55x55 D2 receptor 6CM4 5-HT2C receptor 6BQH
TM5 197 5.56x56 D2 receptor 6CM4 - -
TM5 198 5.57x57 D2 receptor 6CM4 D2 receptor 6CM4
TM5 199 5.58x58 D2 receptor 6CM4 - -
TM5 200 5.59x59 D2 receptor 6CM4 D2 receptor 6CM4
TM5 201 5.60x60 D2 receptor 6CM4 - -
TM5 202 5.61x61 D2 receptor 6CM4 - -
TM5 203 5.62x62 D2 receptor 6CM4 D2 receptor 6CM4
TM5 204 5.63x63 D2 receptor 6CM4 β2-adrenoceptor 2RH1
TM5 205 5.64x64 D2 receptor 6CM4 Rhodopsin 1GZM
TM5 206 5.65x65 D2 receptor 6CM4 D2 receptor 6CM4
TM5 207 5.66x66 D2 receptor 6CM4 OX2 receptor 5WS3
TM5 208 5.67x67 D2 receptor 6CM4 - -
TM5 209 5.68x68 D2 receptor 6CM4 D2 receptor 6CM4
TM5 210 5.69x69 D2 receptor 6CM4 - -
TM5 211 5.70x70 D2 receptor 6CM4 - -
TM5 212 5.71x71 D2 receptor 6CM4 P2Y12 receptor 4NTJ
TM5 213 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 214 5.73x73 β2-adrenoceptor 3SN6 - -
TM5 215 5.74x74 β2-adrenoceptor 3SN6 - -
ICL3 216 - - - -
ICL3 217 - - - -
ICL3 218 - - - -
ICL3 219 - - - -
ICL3 220 - - - -
ICL3 256 - - - -
ICL3 257 - - - -
ICL3 258 - - - -
ICL3 259 - - - -
ICL3 260 - - - -
TM6 261 6.24x24 A1 receptor 6D9H - -
TM6 262 6.25x25 A1 receptor 6D9H A2A receptor 3VG9
TM6 263 6.26x26 A1 receptor 6D9H 5-HT2C receptor 6BQH
TM6 264 6.27x27 A1 receptor 6D9H - -
TM6 265 6.28x28 A1 receptor 6D9H - -
TM6 266 6.29x29 A1 receptor 6D9H δ receptor 4N6H
TM6 267 6.30x30 D2 receptor 6CM4 NTS1 receptor 4BUO
TM6 268 6.31x31 D2 receptor 6CM4 5-HT2B receptor 4IB4
TM6 269 6.32x32 D2 receptor 6CM4 - -
TM6 270 6.33x33 D2 receptor 6CM4 OX2 receptor 5WS3
TM6 271 6.34x34 D2 receptor 6CM4 Y1 receptor 5ZBH
TM6 272 6.35x35 D2 receptor 6CM4 NTS1 receptor 4BUO
TM6 273 6.36x36 D2 receptor 6CM4 5-HT2C receptor 6BQH
TM6 274 6.37x37 D2 receptor 6CM4 - -
TM6 275 6.38x38 D2 receptor 6CM4 D2 receptor 6CM4
TM6 276 6.39x39 D2 receptor 6CM4 D2 receptor 6CM4
TM6 277 6.40x40 D2 receptor 6CM4 D2 receptor 6CM4
TM6 278 6.41x41 D2 receptor 6CM4 5-HT2C receptor 6BQH
TM6 279 6.42x42 D2 receptor 6CM4 M2 receptor 3UON
TM6 280 6.43x43 D2 receptor 6CM4 - -
TM6 281 6.44x44 D2 receptor 6CM4 - -
TM6 282 6.45x45 D2 receptor 6CM4 - -
TM6 283 6.46x46 D2 receptor 6CM4 A1 receptor 5UEN
TM6 284 6.47x47 D2 receptor 6CM4 M2 receptor 3UON
TM6 285 6.48x48 D2 receptor 6CM4 FFA1 receptor 5KW2
TM6 286 6.49x49 D2 receptor 6CM4 Rhodopsin 4ZWJ
TM6 287 6.50x50 D2 receptor 6CM4 D2 receptor 6CM4
TM6 288 6.51x51 D2 receptor 6CM4 OX2 receptor 5WS3
TM6 289 6.52x52 D2 receptor 6CM4 CB1 receptor 5TGZ
TM6 290 6.53x53 D2 receptor 6CM4 M2 receptor 3UON
TM6 291 6.54x54 D2 receptor 6CM4 D4 receptor 5WIV
TM6 292 6.55x55 D2 receptor 6CM4 5-HT1B receptor 4IAQ
TM6 293 6.56x56 D2 receptor 6CM4 Rhodopsin 1GZM
TM6 294 6.57x57 D2 receptor 6CM4 A2A receptor 3VG9
TM6 295 6.58x58 D2 receptor 6CM4 5-HT2C receptor 6BQH
TM6 296 6.59x59 D2 receptor 6CM4 A1 receptor 5UEN
TM6 297 6.60x60 D2 receptor 6CM4 FFA1 receptor 5KW2
TM6 298 6.61x61 D2 receptor 6CM4 P2Y12 receptor 4PXZ
ECL3 299 D2 receptor 6CM4 - -
ECL3 300 D2 receptor 6CM4 - -
ECL3 301 D2 receptor 6CM4 - -
ECL3 302 D2 receptor 6CM4 - -
TM7 303 7.32x31 D2 receptor 6CM4 D2 receptor 6CM4
TM7 304 7.33x32 D2 receptor 6CM4 A2A receptor 3VG9
TM7 305 7.34x33 D2 receptor 6CM4 - -
TM7 306 7.35x34 D2 receptor 6CM4 D4 receptor 5WIV
TM7 307 7.36x35 D2 receptor 6CM4 Y1 receptor 5ZBH
TM7 308 7.37x36 D2 receptor 6CM4 D2 receptor 6CM4
TM7 309 7.38x37 D2 receptor 6CM4 D4 receptor 5WIV
TM7 310 7.39x38 D2 receptor 6CM4 S1P1 receptor 3V2Y
TM7 311 7.40x39 D2 receptor 6CM4 D2 receptor 6CM4
TM7 312 7.41x40 D2 receptor 6CM4 - -
TM7 313 7.42x41 D2 receptor 6CM4 A2A receptor 3VG9
TM7 314 7.43x42 D2 receptor 6CM4 Y1 receptor 5ZBH
TM7 315 7.44x43 D2 receptor 6CM4 OX2 receptor 5WS3
TM7 316 7.45x45 D2 receptor 6CM4 - -
TM7 317 7.46x46 D2 receptor 6CM4 Y1 receptor 5ZBH
TM7 318 7.47x47 D2 receptor 6CM4 5-HT1B receptor 4IAQ
TM7 319 7.48x48 D2 receptor 6CM4 D3 receptor 3PBL
TM7 320 7.49x49 D2 receptor 6CM4 - -
TM7 321 7.50x50 D2 receptor 6CM4 D2 receptor 6CM4
TM7 322 7.51x51 D2 receptor 6CM4 - -
TM7 323 7.52x52 D2 receptor 6CM4 Y1 receptor 5ZBH
TM7 324 7.53x53 D2 receptor 6CM4 - -
TM7 325 7.54x54 D2 receptor 6CM4 - -
TM7 326 7.55x55 D2 receptor 6CM4 - -
H8 327 8.47x47 D2 receptor 6CM4 P2Y12 receptor 4NTJ
H8 328 8.48x48 D2 receptor 6CM4 H1 receptor 3RZE
H8 329 8.49x49 D2 receptor 6CM4 ETB receptor 5GLI
H8 330 8.50x50 D2 receptor 6CM4 5-HT2C receptor 6BQH
H8 331 8.51x51 D2 receptor 6CM4 5-HT2C receptor 6BQH
H8 332 8.52x52 D2 receptor 6CM4 LPA1 receptor 4Z35
H8 333 8.53x53 D2 receptor 6CM4 Y1 receptor 5ZBH
H8 334 8.54x54 D2 receptor 6CM4 - -
H8 335 8.55x55 D2 receptor 6CM4 M4 receptor 5DSG
H8 336 8.56x56 D2 receptor 6CM4 M3 receptor 4U15
H8 337 8.57x57 D2 receptor 6CM4 AT2 receptor 5UNG
H8 338 8.58x58 D2 receptor 6CM4 A1 receptor 5UEN
C-term 339 - - - -
C-term 340 - - - -
C-term 341 - - - -
C-term 342 - - - -
C-term 343 - - - -