GPR173 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 7.28 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 39%) PDB: 6DDE

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 67.0 12.6 20.5
Side-chains 13.5 45.9 40.6

Number of backbone templates: 6
Number of rotamer templates: 41

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6DDE
5C1M
5WIV
3SN6
4UHR
6BQH
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 17 - - - -
N-term 18 - - - -
N-term 19 - - - -
N-term 20 μ receptor 6DDE μ receptor 6DDE
N-term 21 μ receptor 6DDE μ receptor 6DDE
TM1 22 1.32x32 μ receptor 6DDE μ receptor 6DDE
TM1 23 1.33x33 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 24 1.34x34 μ receptor 6DDE A2A receptor 4UHR
TM1 25 1.35x35 μ receptor 6DDE - -
TM1 26 1.36x36 μ receptor 6DDE D4 receptor 5WIV
TM1 27 1.37x37 μ receptor 6DDE D4 receptor 5WIV
TM1 28 1.38x38 μ receptor 6DDE 5-HT2B receptor 4IB4
TM1 29 1.39x39 μ receptor 6DDE 5-HT2B receptor 4IB4
TM1 30 1.40x40 μ receptor 6DDE M4 receptor 5DSG
TM1 31 1.41x41 μ receptor 6DDE 5-HT2B receptor 4IB4
TM1 32 1.42x42 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 33 1.43x43 μ receptor 6DDE BLT1 receptor 5X33
TM1 34 1.44x44 μ receptor 6DDE S1P1 receptor 3V2Y
TM1 35 1.45x45 μ receptor 6DDE μ receptor 6DDE
TM1 36 1.46x46 μ receptor 6DDE PAR1 3VW7
TM1 37 1.47x47 μ receptor 6DDE PAR2 5NDD
TM1 38 1.48x48 μ receptor 6DDE D4 receptor 5WIV
TM1 39 1.49x49 μ receptor 6DDE μ receptor 6DDE
TM1 40 1.50x50 μ receptor 6DDE μ receptor 6DDE
TM1 41 1.51x51 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 42 1.52x52 μ receptor 6DDE - -
TM1 43 1.53x53 μ receptor 6DDE ETB receptor 5X93
TM1 44 1.54x54 μ receptor 6DDE - -
TM1 45 1.55x55 μ receptor 6DDE 5-HT2B receptor 4IB4
TM1 46 1.56x56 μ receptor 6DDE AT2 receptor 5UNG
TM1 47 1.57x57 μ receptor 6DDE 5-HT2B receptor 4IB4
TM1 48 1.58x58 μ receptor 6DDE PAR2 5NDD
TM1 49 1.59x59 μ receptor 6DDE OX2 receptor 5WS3
TM1 50 1.60x60 μ receptor 6DDE C5a1 receptor 5O9H
ICL1 51 12.48x48 - - - -
ICL1 52 12.49x49 D4 receptor 5WIV D4 receptor 5WIV
ICL1 53 12.50x50 D4 receptor 5WIV D4 receptor 5WIV
ICL1 54 12.51x51 - - - -
TM2 55 2.37x37 D4 receptor 5WIV PAR1 3VW7
TM2 56 2.38x38 μ receptor 6DDE μ receptor 6DDE
TM2 57 2.39x39 μ receptor 6DDE ETB receptor 5X93
TM2 58 2.40x40 μ receptor 6DDE CB1 receptor 5XRA
TM2 59 2.41x41 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 60 2.42x42 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 61 2.43x43 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 62 2.44x44 μ receptor 6DDE PAR1 3VW7
TM2 63 2.45x45 μ receptor 6DDE - -
TM2 64 2.46x46 μ receptor 6DDE μ receptor 6DDE
TM2 65 2.47x47 μ receptor 6DDE - -
TM2 66 2.48x48 μ receptor 6DDE μ receptor 6DDE
TM2 67 2.49x49 μ receptor 6DDE μ receptor 6DDE
TM2 68 2.50x50 μ receptor 6DDE μ receptor 6DDE
TM2 69 2.51x51 μ receptor 6DDE - -
TM2 70 2.52x52 μ receptor 6DDE H1 receptor 3RZE
TM2 71 2.53x53 μ receptor 6DDE - -
TM2 72 2.54x54 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM2 73 2.55x55 D4 receptor 5WIV OX1 receptor 4ZJ8
TM2 74 2.56x551 D4 receptor 5WIV H1 receptor 3RZE
TM2 75 2.57x56 D4 receptor 5WIV OX1 receptor 4ZJ8
TM2 76 2.58x57 μ receptor 6DDE PAR2 5NDD
TM2 77 2.59x58 μ receptor 6DDE μ receptor 6DDE
TM2 78 2.60x59 μ receptor 6DDE μ receptor 6DDE
TM2 79 2.61x60 μ receptor 6DDE D2 receptor 6CM4
TM2 80 2.62x61 μ receptor 6DDE 5-HT2B receptor 4IB4
TM2 81 2.63x62 μ receptor 6DDE A2A receptor 4UHR
TM2 82 2.64x63 μ receptor 6DDE P2Y12 receptor 4NTJ
TM2 83 2.65x64 μ receptor 6DDE - -
TM2 84 2.66x65 μ receptor 6DDE - -
TM2 85 2.67x66 μ receptor 6DDE PAR2 5NDD
ECL1 86 - - - -
ECL1 87 D4 receptor 5WIV - -
ECL1 88 23.49x49 D4 receptor 5WIV OX1 receptor 4ZJ8
ECL1 89 23.50x50 D4 receptor 5WIV D4 receptor 5WIV
ECL1 90 23.51x51 D4 receptor 5WIV 5-HT1B receptor 4IAQ
ECL1 91 23.52x52 - - - -
TM3 92 3.21x21 μ receptor 6DDE D4 receptor 5WIV
TM3 93 3.22x22 μ receptor 6DDE FFA1 receptor 5TZY
TM3 94 3.23x23 μ receptor 6DDE δ receptor 4N6H
TM3 95 3.24x24 μ receptor 6DDE - -
TM3 96 3.25x25 μ receptor 6DDE μ receptor 6DDE
TM3 97 3.26x26 μ receptor 6DDE μ receptor 6DDE
TM3 98 3.27x27 μ receptor 6DDE μ receptor 6DDE
TM3 99 3.28x28 μ receptor 6DDE μ receptor 6DDE
TM3 100 3.29x29 μ receptor 6DDE A2A receptor 4UHR
TM3 101 3.30x30 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 102 3.31x31 μ receptor 6DDE D4 receptor 5WIV
TM3 103 3.32x32 μ receptor 6DDE Rhodopsin 5DYS
TM3 104 3.33x33 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 105 3.34x34 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 106 3.35x35 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 107 3.36x36 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM3 108 3.37x37 μ receptor 6DDE μ receptor 6DDE
TM3 109 3.38x38 μ receptor 6DDE - -
TM3 110 3.39x39 μ receptor 6DDE A2A receptor 5WF6
TM3 111 3.40x40 μ receptor 6DDE NTS1 receptor 4XES
TM3 112 3.41x41 μ receptor 6DDE μ receptor 6DDE
TM3 113 3.42x42 μ receptor 6DDE - -
TM3 114 3.43x43 μ receptor 6DDE μ receptor 6DDE
TM3 115 3.44x44 μ receptor 6DDE H1 receptor 3RZE
TM3 116 3.45x45 μ receptor 6DDE PAR2 5NDD
TM3 117 3.46x46 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 118 3.47x47 μ receptor 6DDE μ receptor 6DDE
TM3 119 3.48x48 μ receptor 6DDE μ receptor 6DDE
TM3 120 3.49x49 μ receptor 6DDE - -
TM3 121 3.50x50 μ receptor 6DDE μ receptor 6DDE
TM3 122 3.51x51 μ receptor 6DDE μ receptor 6DDE
TM3 123 3.52x52 μ receptor 6DDE - -
TM3 124 3.53x53 μ receptor 6DDE μ receptor 6DDE
TM3 125 3.54x54 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 126 3.55x55 μ receptor 6DDE FFA1 receptor 5TZY
TM3 127 3.56x56 μ receptor 6DDE μ receptor 6DDE
ICL2 128 34.50x50 - - - -
ICL2 129 34.51x51 μ receptor 5C1M - -
ICL2 130 34.52x52 μ receptor 5C1M CCR2 5T1A
ICL2 131 34.53x53 μ receptor 5C1M 5-HT1B receptor 4IAQ
ICL2 132 34.54x54 μ receptor 5C1M - -
ICL2 133 34.55x55 μ receptor 5C1M BLT1 receptor 5X33
ICL2 134 34.56x56 μ receptor 5C1M P2Y1 receptor 4XNW
ICL2 135 34.57x57 - - - -
TM4 136 4.38x38 μ receptor 6DDE μ receptor 6DDE
TM4 137 4.39x39 μ receptor 6DDE PAR1 3VW7
TM4 138 4.40x40 μ receptor 6DDE AT2 receptor 5UNF
TM4 139 4.41x41 μ receptor 6DDE 5-HT2B receptor 4IB4
TM4 140 4.42x42 μ receptor 6DDE - -
TM4 141 4.43x43 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM4 142 4.44x44 μ receptor 6DDE H1 receptor 3RZE
TM4 143 4.45x45 μ receptor 6DDE μ receptor 6DDE
TM4 144 4.46x46 μ receptor 6DDE 5-HT2B receptor 4IB4
TM4 145 4.47x47 μ receptor 6DDE CB1 receptor 5XRA
TM4 146 4.48x48 μ receptor 6DDE β2-adrenoceptor 3SN6
TM4 147 4.49x49 μ receptor 6DDE H1 receptor 3RZE
TM4 148 4.50x50 μ receptor 6DDE μ receptor 6DDE
TM4 149 4.51x51 μ receptor 6DDE CB1 receptor 5XRA
TM4 150 4.52x52 μ receptor 6DDE μ receptor 6DDE
TM4 151 4.53x53 μ receptor 6DDE μ receptor 6DDE
TM4 152 4.54x54 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 153 4.55x55 μ receptor 6DDE μ receptor 6DDE
TM4 154 4.56x56 μ receptor 6DDE LPA1 receptor 4Z35
TM4 155 4.57x57 μ receptor 6DDE 5-HT2B receptor 4IB4
TM4 156 4.58x58 μ receptor 6DDE β2-adrenoceptor 3SN6
TM4 157 4.59x59 μ receptor 6DDE μ receptor 6DDE
TM4 158 4.60x60 μ receptor 6DDE 5-HT2B receptor 4IB4
TM4 159 4.61x61 μ receptor 6DDE 5-HT2B receptor 4IB4
TM4 160 4.62x62 μ receptor 6DDE μ receptor 6DDE
TM4 161 4.63x63 D4 receptor 5WIV - -
TM4 162 4.64x64 D4 receptor 5WIV - -
ECL2 163 μ receptor 6DDE - -
ECL2 164 μ receptor 6DDE μ receptor 6DDE
ECL2 165 μ receptor 6DDE - -
ECL2 166 μ receptor 6DDE - -
ECL2 167 μ receptor 6DDE - -
ECL2 168 μ receptor 6DDE - -
ECL2 169 μ receptor 6DDE - -
ECL2 170 μ receptor 6DDE - -
ECL2 171 μ receptor 6DDE - -
ECL2 172 μ receptor 6DDE μ receptor 6DDE
ECL2 173 - - - -
ECL2 174 45.50x50 μ receptor 6DDE μ receptor 6DDE
ECL2 175 45.51x51 μ receptor 6DDE AT2 receptor 5UNG
ECL2 176 45.52x52 μ receptor 6DDE β2-adrenoceptor 5JQH
ECL2 177 - - - -
ECL2 178 - - - -
ECL2 179 - - - -
ECL2 180 - - - -
ECL2 181 - - - -
ECL2 182 - - - -
ECL2 183 - - - -
ECL2 184 - - - -
ECL2 185 - - - -
ECL2 186 - - - -
ECL2 187 - - - -
ECL2 188 - - - -
ECL2 189 - - - -
ECL2 190 - - - -
ECL2 191 - - - -
ECL2 192 - - - -
ECL2 193 - - - -
ECL2 194 - - - -
ECL2 195 - - - -
ECL2 196 - - - -
ECL2 197 - - - -
ECL2 198 - - - -
ECL2 199 - - - -
ECL2 200 - - - -
ECL2 201 - - - -
ECL2 202 - - - -
ECL2 203 - - - -
ECL2 204 - - - -
ECL2 205 - - - -
ECL2 206 - - - -
ECL2 207 - - - -
ECL2 208 - - - -
ECL2 209 - - - -
ECL2 210 - - - -
ECL2 211 - - - -
ECL2 212 - - - -
ECL2 213 - - - -
ECL2 214 - - - -
ECL2 215 - - - -
ECL2 216 - - - -
ECL2 217 - - - -
ECL2 218 - - - -
ECL2 219 - - - -
TM5 220 5.35x36 μ receptor 6DDE NTS1 receptor 4XES
TM5 221 5.36x37 μ receptor 6DDE β2-adrenoceptor 3SN6
TM5 222 5.37x38 μ receptor 6DDE OX2 receptor 5WS3
TM5 223 5.38x39 μ receptor 6DDE NTS1 receptor 4XES
TM5 224 5.39x40 μ receptor 6DDE - -
TM5 225 5.40x41 μ receptor 6DDE PAR1 3VW7
TM5 226 5.41x42 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 227 5.42x43 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM5 228 5.43x44 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 229 5.44x45 μ receptor 6DDE - -
TM5 230 5.45x46 μ receptor 6DDE - -
TM5 231 5.46x461 μ receptor 6DDE OX1 receptor 4ZJ8
TM5 232 5.47x47 μ receptor 6DDE μ receptor 6DDE
TM5 233 5.48x48 μ receptor 6DDE - -
TM5 234 5.49x49 μ receptor 6DDE Y1 receptor 5ZBH
TM5 235 5.50x50 μ receptor 6DDE μ receptor 6DDE
TM5 236 5.51x51 μ receptor 6DDE CXCR4 3ODU
TM5 237 5.52x52 μ receptor 6DDE 5-HT2B receptor 4IB4
TM5 238 5.53x53 μ receptor 6DDE C5a1 receptor 5O9H
TM5 239 5.54x54 μ receptor 6DDE - -
TM5 240 5.55x55 μ receptor 6DDE - -
TM5 241 5.56x56 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM5 242 5.57x57 μ receptor 6DDE PAR2 5NDD
TM5 243 5.58x58 μ receptor 6DDE - -
TM5 244 5.59x59 μ receptor 6DDE - -
TM5 245 5.60x60 μ receptor 6DDE - -
TM5 246 5.61x61 μ receptor 6DDE NTS1 receptor 4XES
TM5 247 5.62x62 μ receptor 6DDE NTS1 receptor 4XES
TM5 248 5.63x63 μ receptor 6DDE LPA1 receptor 4Z35
TM5 249 5.64x64 μ receptor 6DDE - -
TM5 250 5.65x65 μ receptor 6DDE - -
TM5 251 5.66x66 μ receptor 6DDE 5-HT1B receptor 4IAR
TM5 252 5.67x67 μ receptor 6DDE - -
TM5 253 5.68x68 μ receptor 6DDE - -
TM5 254 5.69x69 β2-adrenoceptor 3SN6 - -
TM5 255 5.70x70 β2-adrenoceptor 3SN6 - -
TM5 256 5.71x71 β2-adrenoceptor 3SN6 - -
TM5 257 5.72x72 β2-adrenoceptor 3SN6 P2Y12 receptor 4NTJ
TM5 258 5.73x73 β2-adrenoceptor 3SN6 - -
TM5 259 5.74x74 β2-adrenoceptor 3SN6 - -
ICL3 260 - - - -
ICL3 261 - - - -
ICL3 262 - - - -
ICL3 263 - - - -
ICL3 264 - - - -
ICL3 267 - - - -
ICL3 268 - - - -
ICL3 269 - - - -
ICL3 270 - - - -
ICL3 271 - - - -
TM6 272 6.21x21 A2A receptor 4UHR - -
TM6 273 6.22x22 A2A receptor 4UHR - -
TM6 274 6.23x23 μ receptor 6DDE - -
TM6 275 6.24x24 μ receptor 6DDE - -
TM6 276 6.25x25 μ receptor 6DDE ETB receptor 5X93
TM6 277 6.26x26 μ receptor 6DDE - -
TM6 278 6.27x27 μ receptor 6DDE NTS1 receptor 4BUO
TM6 279 6.28x28 μ receptor 6DDE Rhodopsin 5DYS
TM6 280 6.29x29 μ receptor 6DDE - -
TM6 281 6.30x30 μ receptor 6DDE 5-HT2B receptor 4IB4
TM6 282 6.31x31 μ receptor 6DDE PAR1 3VW7
TM6 283 6.32x32 μ receptor 6DDE AT2 receptor 5UNG
TM6 284 6.33x33 μ receptor 6DDE FFA1 receptor 5KW2
TM6 285 6.34x34 μ receptor 6DDE - -
TM6 286 6.35x35 μ receptor 6DDE μ receptor 6DDE
TM6 287 6.36x36 μ receptor 6DDE μ receptor 6DDE
TM6 288 6.37x37 μ receptor 6DDE - -
TM6 289 6.38x38 μ receptor 6DDE - -
TM6 290 6.39x39 μ receptor 6DDE NTS1 receptor 4XES
TM6 291 6.40x40 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM6 292 6.41x41 μ receptor 6DDE - -
TM6 293 6.42x42 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 294 6.43x43 μ receptor 6DDE 5-HT2B receptor 4IB4
TM6 295 6.44x44 μ receptor 6DDE μ receptor 6DDE
TM6 296 6.45x45 μ receptor 6DDE 5-HT2B receptor 4IB4
TM6 297 6.46x46 μ receptor 6DDE 5-HT2B receptor 4IB4
TM6 298 6.47x47 μ receptor 6DDE - -
TM6 299 6.48x48 μ receptor 6DDE μ receptor 6DDE
TM6 300 6.49x49 μ receptor 6DDE - -
TM6 301 6.50x50 μ receptor 6DDE μ receptor 6DDE
TM6 302 6.51x51 μ receptor 6DDE NTS1 receptor 4XES
TM6 303 6.52x52 μ receptor 6DDE - -
TM6 304 6.53x53 μ receptor 6DDE NTS1 receptor 4XES
TM6 305 6.54x54 μ receptor 6DDE P2Y12 receptor 4NTJ
TM6 306 6.55x55 μ receptor 6DDE - -
TM6 307 6.56x56 μ receptor 6DDE - -
TM6 308 6.57x57 μ receptor 6DDE - -
TM6 309 6.58x58 μ receptor 6DDE - -
TM6 310 6.59x59 μ receptor 6DDE 5-HT2B receptor 4IB4
TM6 311 6.60x60 μ receptor 6DDE A2A receptor 4UHR
TM6 312 6.61x61 μ receptor 6DDE δ receptor 4N6H
ECL3 313 - - - -
ECL3 314 D4 receptor 5WIV D4 receptor 5WIV
ECL3 315 D4 receptor 5WIV D4 receptor 5WIV
ECL3 316 D4 receptor 5WIV - -
ECL3 317 - - - -
TM7 318 7.31x30 μ receptor 6DDE M2 receptor 4MQT
TM7 319 7.32x31 μ receptor 6DDE NTS1 receptor 4XES
TM7 320 7.33x32 μ receptor 6DDE D4 receptor 5WIU
TM7 321 7.34x33 μ receptor 6DDE M3 receptor 4U15
TM7 322 7.35x34 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 323 7.36x35 μ receptor 6DDE CB1 receptor 5XRA
TM7 324 7.37x36 μ receptor 6DDE - -
TM7 325 7.38x37 μ receptor 6DDE A2A receptor 4UHR
TM7 326 7.39x38 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 327 7.40x39 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 328 7.41x40 μ receptor 6DDE ETB receptor 5X93
TM7 329 7.42x41 μ receptor 6DDE A2A receptor 4UHR
TM7 330 7.43x42 μ receptor 6DDE AT2 receptor 5UNG
TM7 331 7.44x43 μ receptor 6DDE NTS1 receptor 4XES
TM7 332 7.45x45 μ receptor 6DDE - -
TM7 333 7.46x46 μ receptor 6DDE P2Y12 receptor 4NTJ
TM7 334 7.47x47 μ receptor 6DDE NTS1 receptor 4XES
TM7 335 7.48x48 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 336 7.49x49 μ receptor 6DDE μ receptor 6DDE
TM7 337 7.50x50 μ receptor 6DDE μ receptor 6DDE
TM7 338 7.51x51 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM7 339 7.52x52 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 340 7.53x53 μ receptor 6DDE - -
TM7 341 7.54x54 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 342 7.55x55 D4 receptor 5WIV 5-HT2B receptor 4IB4
TM7 343 7.56x56 D4 receptor 5WIV P2Y12 receptor 4NTJ
H8 344 8.47x47 D4 receptor 5WIV 5-HT2B receptor 4IB4
H8 345 8.48x48 D4 receptor 5WIV 5-HT2B receptor 5TVN
H8 346 8.49x49 D4 receptor 5WIV 5-HT1B receptor 4IAQ
H8 347 8.50x50 D4 receptor 5WIV CB1 receptor 5XRA
H8 348 8.51x51 D4 receptor 5WIV 5-HT1B receptor 4IAQ
H8 349 8.52x52 D4 receptor 5WIV D3 receptor 3PBL
H8 350 8.53x53 D4 receptor 5WIV μ receptor 4DKL
H8 351 8.54x54 D4 receptor 5WIV Y1 receptor 5ZBH
H8 352 8.55x55 D4 receptor 5WIV A2A receptor 4UHR
H8 353 8.56x56 D4 receptor 5WIV Rhodopsin 5DYS
H8 354 8.57x57 D4 receptor 5WIV - -
H8 355 8.58x58 5-HT2C receptor 6BQH - -
C-term 356 - - - -
C-term 357 - - - -
C-term 358 - - - -
C-term 359 - - - -
C-term 360 - - - -