GPR176 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 5.46 docs)

VERSION

2018-07-10

MAIN TEMPLATE

NTS1 receptor (sequence similarity: 40%) PDB: 4XES

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 73.8 17.4 8.9
Side-chains 14.4 57.4 28.2

Number of backbone templates: 6
Number of rotamer templates: 41

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4XES
5WS3
4NTJ
3ODU
4ZJ8
4UHR
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 36 NTS1 receptor 4XES NTS1 receptor 4XES
N-term 37 NTS1 receptor 4XES NTS1 receptor 4XES
N-term 38 NTS1 receptor 4XES NTS1 receptor 4XES
N-term 39 NTS1 receptor 4XES NTS1 receptor 4XES
N-term 40 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 41 1.32x32 NTS1 receptor 4XES - -
TM1 42 1.33x33 NTS1 receptor 4XES FFA1 receptor 5TZR
TM1 43 1.34x34 NTS1 receptor 4XES PAR1 3VW7
TM1 44 1.35x35 NTS1 receptor 4XES S1P1 receptor 3V2Y
TM1 45 1.36x36 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 46 1.37x37 NTS1 receptor 4XES A2A receptor 4UHR
TM1 47 1.38x38 NTS1 receptor 4XES A2A receptor 4UHR
TM1 48 1.39x39 NTS1 receptor 4XES - -
TM1 49 1.40x40 NTS1 receptor 4XES FFA1 receptor 5TZY
TM1 50 1.41x41 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM1 51 1.42x42 NTS1 receptor 4XES A2A receptor 4UHR
TM1 52 1.43x43 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 53 1.44x44 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM1 54 1.45x45 NTS1 receptor 4XES NOP receptor 5DHG
TM1 55 1.46x46 NTS1 receptor 4XES PAR1 3VW7
TM1 56 1.47x47 NTS1 receptor 4XES PAR1 3VW7
TM1 57 1.48x48 NTS1 receptor 4XES A2A receptor 4UHR
TM1 58 1.49x49 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 59 1.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 60 1.51x51 NTS1 receptor 4XES μ receptor 6DDE
TM1 61 1.52x52 NTS1 receptor 4XES PAR1 3VW7
TM1 62 1.53x53 NTS1 receptor 4XES A2A receptor 4UHR
TM1 63 1.54x54 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 64 1.55x55 NTS1 receptor 4XES A2A receptor 4UHR
TM1 65 1.56x56 NTS1 receptor 4XES D4 receptor 5WIV
TM1 66 1.57x57 NTS1 receptor 4XES Rhodopsin 4ZWJ
TM1 67 1.58x58 NTS1 receptor 4XES AT2 receptor 5UNG
TM1 68 1.59x59 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 69 1.60x60 NTS1 receptor 4XES - -
ICL1 70 12.48x48 - - - -
ICL1 71 12.49x49 OX2 receptor 5WS3 - -
ICL1 72 12.50x50 OX2 receptor 5WS3 S1P1 receptor 3V2Y
ICL1 73 12.51x51 - - - -
TM2 74 2.37x37 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 75 2.38x38 NTS1 receptor 4XES A2A receptor 4UHR
TM2 76 2.39x39 NTS1 receptor 4XES A2A receptor 4UHR
TM2 77 2.40x40 NTS1 receptor 4XES A2A receptor 4UHR
TM2 78 2.41x41 NTS1 receptor 4XES - -
TM2 79 2.42x42 NTS1 receptor 4XES A2A receptor 4UHR
TM2 80 2.43x43 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM2 81 2.44x44 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM2 82 2.45x45 NTS1 receptor 4XES μ receptor 6DDE
TM2 83 2.46x46 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 84 2.47x47 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 85 2.48x48 NTS1 receptor 4XES FFA1 receptor 5TZY
TM2 86 2.49x49 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 87 2.50x50 NTS1 receptor 4XES - -
TM2 88 2.51x51 NTS1 receptor 4XES A2A receptor 4UHR
TM2 89 2.52x52 NTS1 receptor 4XES AT1 receptor 4ZUD
TM2 90 2.53x53 NTS1 receptor 4XES μ receptor 6DDE
TM2 91 2.54x54 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM2 92 2.55x55 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 93 2.56x551 NTS1 receptor 4XES H1 receptor 3RZE
TM2 94 2.57x56 NTS1 receptor 4XES OX2 receptor 5WS3
TM2 95 2.58x57 NTS1 receptor 4XES β2-adrenoceptor 3SN6
TM2 96 2.59x58 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 97 2.60x59 NTS1 receptor 4XES A2A receptor 4UHR
TM2 98 2.61x60 NTS1 receptor 4XES - -
TM2 99 2.62x61 NTS1 receptor 4XES A2A receptor 4UHR
TM2 100 2.63x62 NTS1 receptor 4XES CCR9 5LWE
TM2 101 2.64x63 NTS1 receptor 4XES D3 receptor 3PBL
TM2 102 2.65x64 NTS1 receptor 4XES A2A receptor 4UHR
TM2 103 2.66x65 NTS1 receptor 4XES A2A receptor 4UHR
TM2 104 2.67x66 NTS1 receptor 4XES PAR1 3VW7
ECL1 105 - - - -
ECL1 106 - - - -
ECL1 107 - - - -
ECL1 108 23.49x49 OX2 receptor 5WS3 - -
ECL1 109 23.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL1 110 23.51x51 OX2 receptor 5WS3 - -
ECL1 111 23.52x52 - - - -
TM3 112 3.20x20 P2Y12 receptor 4NTJ - -
TM3 113 3.21x21 NTS1 receptor 4XES S1P1 receptor 3V2Y
TM3 114 3.22x22 NTS1 receptor 4XES - -
TM3 115 3.23x23 NTS1 receptor 4XES δ receptor 4N6H
TM3 116 3.24x24 NTS1 receptor 4XES apelin receptor 5VBL
TM3 117 3.25x25 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 118 3.26x26 NTS1 receptor 4XES μ receptor 6DDE
TM3 119 3.27x27 NTS1 receptor 4XES PAR2 5NDD
TM3 120 3.28x28 NTS1 receptor 4XES μ receptor 6DDE
TM3 121 3.29x29 NTS1 receptor 4XES - -
TM3 122 3.30x30 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 123 3.31x31 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 124 3.32x32 NTS1 receptor 4XES FFA1 receptor 5TZY
TM3 125 3.33x33 NTS1 receptor 4XES ETB receptor 5X93
TM3 126 3.34x34 NTS1 receptor 4XES A2A receptor 4UHR
TM3 127 3.35x35 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM3 128 3.36x36 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM3 129 3.37x37 NTS1 receptor 4XES OX2 receptor 5WS3
TM3 130 3.38x38 NTS1 receptor 4XES OX2 receptor 5WS3
TM3 131 3.39x39 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 132 3.40x40 NTS1 receptor 4XES A2A receptor 4UHR
TM3 133 3.41x41 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 134 3.42x42 NTS1 receptor 4XES A2A receptor 4UHR
TM3 135 3.43x43 NTS1 receptor 4XES - -
TM3 136 3.44x44 NTS1 receptor 4XES - -
TM3 137 3.45x45 NTS1 receptor 4XES A2A receptor 4UHR
TM3 138 3.46x46 NTS1 receptor 4XES A2A receptor 4UHR
TM3 139 3.47x47 NTS1 receptor 4XES A2A receptor 4UHR
TM3 140 3.48x48 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM3 141 3.49x49 NTS1 receptor 4XES A2A receptor 4UHR
TM3 142 3.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 143 3.51x51 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 144 3.52x52 NTS1 receptor 4XES OX2 receptor 5WS3
TM3 145 3.53x53 NTS1 receptor 4XES H1 receptor 3RZE
TM3 146 3.54x54 NTS1 receptor 4XES μ receptor 6DDE
TM3 147 3.55x55 NTS1 receptor 4XES - -
TM3 148 3.56x56 NTS1 receptor 4XES PAR1 3VW7
ICL2 149 - - - -
ICL2 150 OX2 receptor 5WS3 OX2 receptor 5WS3
ICL2 151 OX2 receptor 5WS3 - -
ICL2 152 OX2 receptor 5WS3 - -
ICL2 153 OX2 receptor 5WS3 OX2 receptor 5WS3
ICL2 154 - - - -
TM4 155 4.38x38 NTS1 receptor 4XES NTS1 receptor 4XES
TM4 156 4.39x39 NTS1 receptor 4XES - -
TM4 157 4.40x40 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM4 158 4.41x41 NTS1 receptor 4XES κ receptor 4DJH
TM4 159 4.42x42 NTS1 receptor 4XES FFA1 receptor 5TZY
TM4 160 4.43x43 NTS1 receptor 4XES OX2 receptor 5WS3
TM4 161 4.44x44 NTS1 receptor 4XES - -
TM4 162 4.45x45 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM4 163 4.46x46 NTS1 receptor 4XES Rhodopsin 4ZWJ
TM4 164 4.47x47 NTS1 receptor 4XES - -
TM4 165 4.48x48 NTS1 receptor 4XES - -
TM4 166 4.49x49 NTS1 receptor 4XES NTS1 receptor 4XES
TM4 167 4.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM4 168 4.51x51 NTS1 receptor 4XES PAR1 3VW7
TM4 169 4.52x52 NTS1 receptor 4XES - -
TM4 170 4.53x53 NTS1 receptor 4XES PAR1 3VW7
TM4 171 4.54x54 NTS1 receptor 4XES P2Y1 receptor 4XNW
TM4 172 4.55x55 NTS1 receptor 4XES P2Y1 receptor 4XNW
TM4 173 4.56x56 NTS1 receptor 4XES P2Y1 receptor 4XNW
TM4 174 4.57x57 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM4 175 4.58x59 NTS1 receptor 4XES PAR1 3VW7
TM4 176 4.59x60 NTS1 receptor 4XES NTS1 receptor 4XES
TM4 177 4.60x61 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM4 178 4.61x62 NTS1 receptor 4XES μ receptor 6DDE
TM4 179 4.62x63 NTS1 receptor 4XES OX1 receptor 4ZJ8
TM4 180 4.63x64 NTS1 receptor 4XES OX2 receptor 5WS3
TM4 181 4.64x65 NTS1 receptor 4XES CCR5 5UIW
ECL2 182 - - - -
ECL2 183 CXCR4 3ODU CXCR4 3ODU
ECL2 184 CXCR4 3ODU - -
ECL2 185 CXCR4 3ODU - -
ECL2 186 CXCR4 3ODU - -
ECL2 187 CXCR4 3ODU - -
ECL2 188 CXCR4 3ODU - -
ECL2 189 CXCR4 3ODU - -
ECL2 190 CXCR4 3ODU - -
ECL2 191 - - - -
ECL2 192 45.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
ECL2 193 45.51x51 NTS1 receptor 4XES NTS1 receptor 4XES
ECL2 194 45.52x52 NTS1 receptor 4XES OX2 receptor 5WS3
ECL2 195 - - - -
ECL2 196 OX1 receptor 4ZJ8 OX1 receptor 4ZJ8
ECL2 197 OX1 receptor 4ZJ8 - -
ECL2 198 - - - -
TM5 199 5.32x33 NTS1 receptor 4XES κ receptor 4DJH
TM5 200 5.33x34 NTS1 receptor 4XES OX1 receptor 4ZJ8
TM5 201 5.34x35 NTS1 receptor 4XES - -
TM5 202 5.35x36 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM5 203 5.36x37 NTS1 receptor 4XES PAF receptor 5ZKQ
TM5 204 5.37x38 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 205 5.38x39 NTS1 receptor 4XES A2A receptor 4UHR
TM5 206 5.39x40 NTS1 receptor 4XES D3 receptor 3PBL
TM5 207 5.40x41 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM5 208 5.41x42 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 209 5.42x43 NTS1 receptor 4XES - -
TM5 210 5.43x44 NTS1 receptor 4XES AT1 receptor 4ZUD
TM5 211 5.44x45 NTS1 receptor 4XES PAR2 5NDD
TM5 212 5.45x46 NTS1 receptor 4XES BLT1 receptor 5X33
TM5 213 5.46x461 NTS1 receptor 4XES OX2 receptor 5WS3
TM5 214 5.47x47 NTS1 receptor 4XES A2A receptor 4UHR
TM5 215 5.48x48 NTS1 receptor 4XES μ receptor 6DDE
TM5 216 5.49x49 NTS1 receptor 4XES A2A receptor 4UHR
TM5 217 5.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 218 5.51x51 NTS1 receptor 4XES μ receptor 6DDE
TM5 219 5.52x52 NTS1 receptor 4XES P2Y1 receptor 4XNW
TM5 220 5.53x53 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 221 5.54x54 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM5 222 5.55x55 NTS1 receptor 4XES Y1 receptor 5ZBH
TM5 223 5.56x56 NTS1 receptor 4XES OX2 receptor 5WS3
TM5 224 5.57x57 NTS1 receptor 4XES H1 receptor 3RZE
TM5 225 5.58x58 NTS1 receptor 4XES - -
TM5 226 5.59x59 NTS1 receptor 4XES D2 receptor 6CM4
TM5 227 5.60x60 NTS1 receptor 4XES μ receptor 6DDE
TM5 228 5.61x61 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 229 5.62x62 NTS1 receptor 4XES AT2 receptor 5UNG
TM5 230 5.63x63 NTS1 receptor 4XES PAR1 3VW7
TM5 231 5.64x64 NTS1 receptor 4XES A2A receptor 4UHR
TM5 232 5.65x65 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 233 5.66x66 NTS1 receptor 4XES PAR1 3VW7
TM5 234 5.67x67 NTS1 receptor 4XES - -
TM5 235 5.68x68 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM5 236 5.69x69 NTS1 receptor 4XES - -
TM5 237 5.70x70 A2A receptor 4UHR A2A receptor 4UHR
TM5 238 5.71x71 A2A receptor 4UHR β2-adrenoceptor 3SN6
TM5 239 5.72x72 A2A receptor 4UHR - -
TM5 240 5.73x73 A2A receptor 4UHR - -
TM5 241 5.74x74 A2A receptor 4UHR - -
ICL3 242 - - - -
ICL3 243 - - - -
ICL3 244 - - - -
ICL3 245 - - - -
ICL3 246 - - - -
ICL3 247 - - - -
ICL3 248 - - - -
ICL3 249 - - - -
ICL3 250 - - - -
ICL3 251 - - - -
TM6 252 6.21x21 A2A receptor 4UHR - -
TM6 253 6.22x22 A2A receptor 4UHR - -
TM6 254 6.23x23 A2A receptor 4UHR - -
TM6 255 6.24x24 A2A receptor 4UHR NTS1 receptor 5T04
TM6 256 6.25x25 A2A receptor 4UHR Y1 receptor 5ZBH
TM6 257 6.26x26 A2A receptor 4UHR 5-HT2C receptor 6BQH
TM6 258 6.27x27 A2A receptor 4UHR PAR2 5NDD
TM6 259 6.28x28 A2A receptor 4UHR A2A receptor 4UHR
TM6 260 6.29x29 NTS1 receptor 4XES 5-HT1B receptor 5V54
TM6 261 6.30x30 NTS1 receptor 4XES A2A receptor 4UHR
TM6 262 6.31x31 NTS1 receptor 4XES - -
TM6 263 6.32x32 NTS1 receptor 4XES Rhodopsin 4ZWJ
TM6 264 6.33x33 NTS1 receptor 4XES FFA1 receptor 5KW2
TM6 265 6.34x34 NTS1 receptor 4XES - -
TM6 266 6.35x35 NTS1 receptor 4XES FFA1 receptor 5TZY
TM6 267 6.36x36 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM6 268 6.37x37 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 269 6.38x38 NTS1 receptor 4XES μ receptor 6DDE
TM6 270 6.39x39 NTS1 receptor 4XES Y1 receptor 5ZBH
TM6 271 6.40x40 NTS1 receptor 4XES Rhodopsin 5DYS
TM6 272 6.41x41 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 273 6.42x42 NTS1 receptor 4XES - -
TM6 274 6.43x43 NTS1 receptor 4XES μ receptor 6DDE
TM6 275 6.44x44 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 276 6.45x45 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM6 277 6.46x46 NTS1 receptor 4XES A2A receptor 4UHR
TM6 278 6.47x47 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 279 6.48x48 NTS1 receptor 4XES - -
TM6 280 6.49x49 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM6 281 6.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 282 6.51x51 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 283 6.52x52 NTS1 receptor 4XES Rhodopsin 4ZWJ
TM6 284 6.53x53 NTS1 receptor 4XES - -
TM6 285 6.54x54 NTS1 receptor 4XES PAR1 3VW7
TM6 286 6.55x55 NTS1 receptor 4XES μ receptor 6DDE
TM6 287 6.56x56 NTS1 receptor 4XES PAR2 5NDD
TM6 288 6.57x57 NTS1 receptor 4XES Rhodopsin 4ZWJ
TM6 289 6.58x58 NTS1 receptor 4XES NOP receptor 5DHG
TM6 290 6.59x59 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM6 291 6.60x60 NTS1 receptor 4XES OX2 receptor 5WS3
TM6 292 6.61x61 NTS1 receptor 4XES ETB receptor 5XPR
ECL3 293 NTS1 receptor 4XES - -
ECL3 294 NTS1 receptor 4XES - -
ECL3 295 NTS1 receptor 4XES - -
ECL3 296 NTS1 receptor 4XES - -
ECL3 297 NTS1 receptor 4XES - -
TM7 298 7.31x30 NTS1 receptor 4XES - -
TM7 299 7.32x31 NTS1 receptor 4XES NOP receptor 5DHG
TM7 300 7.33x32 NTS1 receptor 4XES PAR1 3VW7
TM7 301 7.34x33 NTS1 receptor 4XES A2A receptor 4UHR
TM7 302 7.35x34 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM7 303 7.36x35 NTS1 receptor 4XES PAR1 3VW7
TM7 304 7.37x36 NTS1 receptor 4XES - -
TM7 305 7.38x37 NTS1 receptor 4XES A2A receptor 4UHR
TM7 306 7.39x38 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM7 307 7.40x39 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM7 308 7.41x40 NTS1 receptor 4XES NTS1 receptor 4XES
TM7 309 7.42x41 NTS1 receptor 4XES - -
TM7 310 7.43x42 NTS1 receptor 4XES Rhodopsin 4ZWJ
TM7 311 7.44x43 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM7 312 7.45x45 NTS1 receptor 4XES NTS1 receptor 4XES
TM7 313 7.46x46 NTS1 receptor 4XES - -
TM7 314 7.47x47 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM7 315 7.48x48 NTS1 receptor 4XES OX2 receptor 5WS3
TM7 316 7.49x49 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 317 7.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 318 7.51x51 OX2 receptor 5WS3 μ receptor 6DDE
TM7 319 7.52x52 OX2 receptor 5WS3 μ receptor 6DDE
TM7 320 7.53x53 OX2 receptor 5WS3 - -
TM7 321 7.54x54 OX2 receptor 5WS3 - -
TM7 322 7.55x55 OX2 receptor 5WS3 D3 receptor 3PBL
TM7 323 7.56x56 OX2 receptor 5WS3 PAR2 5NDD
H8 324 8.47x47 OX2 receptor 5WS3 5-HT1B receptor 4IAQ
H8 325 8.48x48 OX2 receptor 5WS3 5-HT2B receptor 5TVN
H8 326 8.49x49 OX2 receptor 5WS3 P2Y12 receptor 4NTJ
H8 327 8.50x50 OX2 receptor 5WS3 - -
H8 328 8.51x51 OX2 receptor 5WS3 A2A receptor 4UHR
H8 329 8.52x52 OX2 receptor 5WS3 D3 receptor 3PBL
H8 330 8.53x53 OX2 receptor 5WS3 κ receptor 4DJH
H8 331 8.54x54 OX2 receptor 5WS3 Y1 receptor 5ZBH
H8 332 8.55x55 OX2 receptor 5WS3 S1P1 receptor 3V2Y
H8 333 8.56x56 OX2 receptor 5WS3 - -
H8 334 8.57x57 OX2 receptor 5WS3 NTS1 receptor 4BUO
H8 335 8.58x58 OX2 receptor 5WS3 PAR2 5NDD
C-term 336 - - - -
C-term 337 - - - -
C-term 338 - - - -
C-term 339 - - - -
C-term 340 - - - -