GPR182 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 4.92 docs)

VERSION

2018-07-10

MAIN TEMPLATE

NTS1 receptor (sequence similarity: 45%) PDB: 4XES

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 75.3 15.3 9.5
Side-chains 22.7 52.2 25.1

Number of backbone templates: 5
Number of rotamer templates: 37

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4XES
5VBL
5XSZ
5UNG
4ZUD
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 49 NTS1 receptor 4XES NTS1 receptor 4XES
N-term 50 NTS1 receptor 4XES NTS1 receptor 4XES
N-term 51 NTS1 receptor 4XES NTS1 receptor 4XES
N-term 52 NTS1 receptor 4XES NTS1 receptor 4XES
N-term 53 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 54 1.33x33 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 55 1.34x34 NTS1 receptor 4XES A2A receptor 4UHR
TM1 56 1.35x35 NTS1 receptor 4XES PAR2 5NDD
TM1 57 1.36x36 NTS1 receptor 4XES FFA1 receptor 5TZY
TM1 58 1.37x37 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 59 1.38x38 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM1 60 1.39x39 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 61 1.40x40 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 62 1.41x41 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 63 1.42x42 NTS1 receptor 4XES - -
TM1 64 1.43x43 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 65 1.44x44 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 66 1.45x45 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 67 1.46x46 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 68 1.47x47 NTS1 receptor 4XES PAR2 5NDD
TM1 69 1.48x48 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 70 1.49x49 NTS1 receptor 4XES S1P1 receptor 3V2Y
TM1 71 1.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 72 1.51x51 NTS1 receptor 4XES Y1 receptor 5ZBH
TM1 73 1.52x52 NTS1 receptor 4XES μ receptor 6DDE
TM1 74 1.53x53 NTS1 receptor 4XES μ receptor 6DDE
TM1 75 1.54x54 NTS1 receptor 4XES PAR1 3VW7
TM1 76 1.55x55 NTS1 receptor 4XES CB1 receptor 5XRA
TM1 77 1.56x56 NTS1 receptor 4XES μ receptor 6DDE
TM1 78 1.57x57 NTS1 receptor 4XES - -
TM1 79 1.58x58 NTS1 receptor 4XES A2A receptor 4UHR
TM1 80 1.59x59 NTS1 receptor 4XES NTS1 receptor 4XES
TM1 81 1.60x60 NTS1 receptor 4XES - -
ICL1 82 12.48x48 - - - -
ICL1 83 12.49x49 apelin receptor 5VBL - -
ICL1 84 12.50x50 apelin receptor 5VBL - -
ICL1 85 12.51x51 - - - -
TM2 86 2.37x37 NTS1 receptor 4XES - -
TM2 87 2.38x38 NTS1 receptor 4XES CCR2 5T1A
TM2 88 2.39x39 NTS1 receptor 4XES S1P1 receptor 3V2Y
TM2 89 2.40x40 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM2 90 2.41x41 NTS1 receptor 4XES BLT1 receptor 5X33
TM2 91 2.42x42 NTS1 receptor 4XES μ receptor 6DDE
TM2 92 2.43x43 NTS1 receptor 4XES μ receptor 6DDE
TM2 93 2.44x44 NTS1 receptor 4XES PAR1 3VW7
TM2 94 2.45x45 NTS1 receptor 4XES μ receptor 6DDE
TM2 95 2.46x46 NTS1 receptor 4XES - -
TM2 96 2.47x47 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 97 2.48x48 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM2 98 2.49x49 NTS1 receptor 4XES μ receptor 6DDE
TM2 99 2.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 100 2.51x51 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 101 2.52x52 NTS1 receptor 4XES - -
TM2 102 2.53x53 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 103 2.54x54 NTS1 receptor 4XES PAR2 5NDD
TM2 104 2.55x55 apelin receptor 5VBL NTS1 receptor 4XES
TM2 105 2.56x56 apelin receptor 5VBL FFA1 receptor 5TZY
TM2 106 2.57x57 NTS1 receptor 4XES μ receptor 6DDE
TM2 107 2.58x58 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 108 2.59x59 NTS1 receptor 4XES NTS1 receptor 4XES
TM2 109 2.60x60 NTS1 receptor 4XES PAF receptor 5ZKQ
TM2 110 2.61x61 NTS1 receptor 4XES US28 4XT1
TM2 111 2.62x62 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM2 112 2.63x63 NTS1 receptor 4XES FFA1 receptor 5TZY
TM2 113 2.64x64 NTS1 receptor 4XES - -
TM2 114 2.65x65 NTS1 receptor 4XES A2A receptor 4UHR
TM2 115 2.66x66 NTS1 receptor 4XES NOP receptor 5DHG
TM2 116 2.67x67 NTS1 receptor 4XES apelin receptor 5VBL
ECL1 117 - - - -
ECL1 118 23.49x49 apelin receptor 5VBL μ receptor 5C1M
ECL1 119 23.50x50 apelin receptor 5VBL apelin receptor 5VBL
ECL1 120 23.51x51 apelin receptor 5VBL AT2 receptor 5UNG
ECL1 121 23.52x52 - - - -
TM3 122 3.21x21 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 123 3.22x22 NTS1 receptor 4XES PAR1 3VW7
TM3 124 3.23x23 NTS1 receptor 4XES PAF receptor 5ZKQ
TM3 125 3.24x24 NTS1 receptor 4XES - -
TM3 126 3.25x25 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 127 3.26x26 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 128 3.27x27 NTS1 receptor 4XES PAR1 3VW7
TM3 129 3.28x28 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM3 130 3.29x29 NTS1 receptor 4XES CXCR4 3ODU
TM3 131 3.30x30 NTS1 receptor 4XES apelin receptor 5VBL
TM3 132 3.31x31 NTS1 receptor 4XES PAR2 5NDD
TM3 133 3.32x32 NTS1 receptor 4XES CXCR4 3ODU
TM3 134 3.33x33 NTS1 receptor 4XES PAF receptor 5ZKQ
TM3 135 3.34x34 NTS1 receptor 4XES P2Y1 receptor 4XNW
TM3 136 3.35x35 NTS1 receptor 4XES μ receptor 6DDE
TM3 137 3.36x36 NTS1 receptor 4XES μ receptor 6DDE
TM3 138 3.37x37 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 139 3.38x38 NTS1 receptor 4XES A2A receptor 4UHR
TM3 140 3.39x39 NTS1 receptor 4XES μ receptor 6DDE
TM3 141 3.40x40 NTS1 receptor 4XES μ receptor 6DDE
TM3 142 3.41x41 NTS1 receptor 4XES μ receptor 6DDE
TM3 143 3.42x42 NTS1 receptor 4XES PAR2 5NDD
TM3 144 3.43x43 NTS1 receptor 4XES μ receptor 6DDE
TM3 145 3.44x44 NTS1 receptor 4XES NTS1 receptor 4BUO
TM3 146 3.45x45 NTS1 receptor 4XES PAR2 5NDD
TM3 147 3.46x46 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 148 3.47x47 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 149 3.48x48 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 150 3.49x49 NTS1 receptor 4XES μ receptor 6DDE
TM3 151 3.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 152 3.51x51 NTS1 receptor 4XES NTS1 receptor 4XES
TM3 153 3.52x52 NTS1 receptor 4XES NOP receptor 5DHG
TM3 154 3.53x53 NTS1 receptor 4XES S1P1 receptor 3V2Y
TM3 155 3.54x54 NTS1 receptor 4XES - -
TM3 156 3.55x55 NTS1 receptor 4XES PAF receptor 5ZKQ
TM3 157 3.56x56 NTS1 receptor 4XES BLT1 receptor 5X33
ICL2 158 34.50x50 - - - -
ICL2 159 34.51x51 LPA6 receptor 5XSZ - -
ICL2 160 34.52x52 LPA6 receptor 5XSZ - -
ICL2 161 34.53x53 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 162 34.54x54 LPA6 receptor 5XSZ - -
ICL2 163 34.55x55 LPA6 receptor 5XSZ - -
ICL2 164 34.56x56 LPA6 receptor 5XSZ P2Y1 receptor 4XNW
ICL2 165 34.57x57 - - - -
TM4 166 4.38x38 NTS1 receptor 4XES - -
TM4 167 4.39x39 NTS1 receptor 4XES - -
TM4 168 4.40x40 NTS1 receptor 4XES μ receptor 6DDE
TM4 169 4.41x41 NTS1 receptor 4XES AT1 receptor 4ZUD
TM4 170 4.42x42 NTS1 receptor 4XES - -
TM4 171 4.43x43 NTS1 receptor 4XES OX2 receptor 5WS3
TM4 172 4.44x44 NTS1 receptor 4XES NOP receptor 5DHG
TM4 173 4.45x45 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM4 174 4.46x46 NTS1 receptor 4XES PAR1 3VW7
TM4 175 4.47x47 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM4 176 4.48x48 NTS1 receptor 4XES CXCR4 3ODU
TM4 177 4.49x49 NTS1 receptor 4XES NTS1 receptor 4XES
TM4 178 4.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM4 179 4.51x51 NTS1 receptor 4XES PAF receptor 5ZKQ
TM4 180 4.52x52 NTS1 receptor 4XES μ receptor 6DDE
TM4 181 4.53x53 NTS1 receptor 4XES NTS1 receptor 4XES
TM4 182 4.54x54 NTS1 receptor 4XES NTS1 receptor 4XES
TM4 183 4.55x55 NTS1 receptor 4XES OX2 receptor 5WS3
TM4 184 4.56x56 NTS1 receptor 4XES μ receptor 6DDE
TM4 185 4.57x57 NTS1 receptor 4XES - -
TM4 186 4.58x59 NTS1 receptor 4XES FFA1 receptor 5TZY
TM4 187 4.59x60 NTS1 receptor 4XES NTS1 receptor 4XES
TM4 188 4.60x61 NTS1 receptor 4XES CCR9 5LWE
TM4 189 4.61x62 NTS1 receptor 4XES κ receptor 4DJH
TM4 190 4.62x63 NTS1 receptor 4XES PAR2 5NDD
TM4 191 4.63x64 NTS1 receptor 4XES AT1 receptor 4ZUD
TM4 192 4.64x65 NTS1 receptor 4XES - -
ECL2 193 - - - -
ECL2 194 - - - -
ECL2 195 - - - -
ECL2 196 - - - -
ECL2 197 - - - -
ECL2 198 - - - -
ECL2 199 - - - -
ECL2 200 - - - -
ECL2 201 - - - -
ECL2 202 45.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
ECL2 203 45.51x51 NTS1 receptor 4XES A2A receptor 4UHR
ECL2 204 45.52x52 NTS1 receptor 4XES AT1 receptor 4ZUD
ECL2 205 - - - -
ECL2 206 AT2 receptor 5UNG - -
ECL2 207 AT2 receptor 5UNG AT2 receptor 5UNG
ECL2 208 AT2 receptor 5UNG - -
ECL2 209 - - - -
TM5 210 5.30x31 apelin receptor 5VBL - -
TM5 211 5.31x32 apelin receptor 5VBL AT2 receptor 5UNG
TM5 212 5.32x33 NTS1 receptor 4XES κ receptor 4DJH
TM5 213 5.33x34 NTS1 receptor 4XES - -
TM5 214 5.34x35 NTS1 receptor 4XES μ receptor 6DDE
TM5 215 5.35x36 NTS1 receptor 4XES PAR1 3VW7
TM5 216 5.36x37 NTS1 receptor 4XES PAF receptor 5ZKQ
TM5 217 5.37x38 NTS1 receptor 4XES C5a1 receptor 5O9H
TM5 218 5.38x39 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 219 5.39x40 NTS1 receptor 4XES AT2 receptor 5UNG
TM5 220 5.40x41 NTS1 receptor 4XES PAR2 5NDD
TM5 221 5.41x42 NTS1 receptor 4XES PAR2 5NDD
TM5 222 5.42x43 NTS1 receptor 4XES P2Y1 receptor 4XNW
TM5 223 5.43x44 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 224 5.44x45 NTS1 receptor 4XES PAR2 5NDD
TM5 225 5.45x46 NTS1 receptor 4XES FFA1 receptor 5TZY
TM5 226 5.46x461 NTS1 receptor 4XES apelin receptor 5VBL
TM5 227 5.47x47 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 228 5.48x48 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 229 5.49x49 NTS1 receptor 4XES PAF receptor 5ZKQ
TM5 230 5.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 231 5.51x51 NTS1 receptor 4XES PAF receptor 5ZKQ
TM5 232 5.52x52 NTS1 receptor 4XES D4 receptor 5WIV
TM5 233 5.53x53 NTS1 receptor 4XES PAR2 5NDD
TM5 234 5.54x54 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 235 5.55x55 NTS1 receptor 4XES μ receptor 6DDE
TM5 236 5.56x56 NTS1 receptor 4XES μ receptor 6DDE
TM5 237 5.57x57 NTS1 receptor 4XES ETB receptor 5X93
TM5 238 5.58x58 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 239 5.59x59 NTS1 receptor 4XES PAR2 5NDD
TM5 240 5.60x60 NTS1 receptor 4XES μ receptor 6DDE
TM5 241 5.61x61 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM5 242 5.62x62 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 243 5.63x63 NTS1 receptor 4XES ETB receptor 5X93
TM5 244 5.64x64 NTS1 receptor 4XES μ receptor 6DDE
TM5 245 5.65x65 NTS1 receptor 4XES NTS1 receptor 4XES
TM5 246 5.66x66 NTS1 receptor 4XES 5-HT1B receptor 4IAR
TM5 247 5.67x67 NTS1 receptor 4XES - -
TM5 248 5.68x68 NTS1 receptor 4XES - -
ICL3 249 - - - -
ICL3 250 - - - -
ICL3 251 - - - -
ICL3 252 - - - -
TM6 253 6.30x30 NTS1 receptor 4XES C5a1 receptor 6C1R
TM6 254 6.31x31 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 255 6.32x32 NTS1 receptor 4XES μ receptor 6DDE
TM6 256 6.33x33 NTS1 receptor 4XES - -
TM6 257 6.34x34 NTS1 receptor 4XES - -
TM6 258 6.35x35 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 259 6.36x36 NTS1 receptor 4XES CCR5 5UIW
TM6 260 6.37x37 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 261 6.38x38 NTS1 receptor 4XES - -
TM6 262 6.39x39 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 263 6.40x40 NTS1 receptor 4XES Rhodopsin 4ZWJ
TM6 264 6.41x41 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 265 6.42x42 NTS1 receptor 4XES μ receptor 6DDE
TM6 266 6.43x43 NTS1 receptor 4XES μ receptor 6DDE
TM6 267 6.44x44 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 268 6.45x45 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 269 6.46x46 NTS1 receptor 4XES - -
TM6 270 6.47x47 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 271 6.48x48 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 272 6.49x49 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 273 6.50x50 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 274 6.51x51 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 275 6.52x52 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 276 6.53x53 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 277 6.54x54 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM6 278 6.55x55 NTS1 receptor 4XES PAR2 5NDD
TM6 279 6.56x56 NTS1 receptor 4XES NTS1 receptor 4XES
TM6 280 6.57x57 NTS1 receptor 4XES apelin receptor 5VBL
TM6 281 6.58x58 NTS1 receptor 4XES 5-HT2B receptor 4IB4
TM6 282 6.59x59 NTS1 receptor 4XES PAF receptor 5ZKQ
TM6 283 6.60x60 NTS1 receptor 4XES PAF receptor 5ZKQ
TM6 284 6.61x61 NTS1 receptor 4XES Rhodopsin 5DYS
TM6 285 6.62x62 AT1 receptor 4ZUD - -
TM6 286 6.63x63 AT1 receptor 4ZUD P2Y12 receptor 4PXZ
TM6 287 6.64x64 AT1 receptor 4ZUD - -
ECL3 288 - - - -
ECL3 289 AT1 receptor 4ZUD - -
ECL3 290 - - - -
TM7 291 7.24x23 NTS1 receptor 4XES - -
TM7 292 7.25x24 NTS1 receptor 4XES P2Y1 receptor 4XNW
TM7 293 7.26x25 NTS1 receptor 4XES - -
TM7 294 7.27x26 NTS1 receptor 4XES NTS1 receptor 4XES
TM7 295 7.28x27 NTS1 receptor 4XES - -
TM7 296 7.29x28 NTS1 receptor 4XES - -
TM7 297 7.30x29 NTS1 receptor 4XES C5a1 receptor 5O9H
TM7 298 7.31x30 NTS1 receptor 4XES P2Y12 receptor 4NTJ
TM7 299 7.32x31 NTS1 receptor 4XES PAR2 5NDD
TM7 300 7.33x32 NTS1 receptor 4XES PAR1 3VW7
TM7 301 7.34x33 NTS1 receptor 4XES NTS1 receptor 4XES
TM7 302 7.35x34 NTS1 receptor 4XES NTS1 receptor 4XES
TM7 303 7.36x35 NTS1 receptor 4XES 5-HT1B receptor 4IAQ
TM7 304 7.37x36 NTS1 receptor 4XES PAR2 5NDD
TM7 305 7.38x37 NTS1 receptor 4XES - -
TM7 306 7.39x38 NTS1 receptor 4XES - -
TM7 307 7.40x39 NTS1 receptor 4XES PAR2 5NDD
TM7 308 7.41x40 NTS1 receptor 4XES C5a1 receptor 5O9H
TM7 309 7.42x41 NTS1 receptor 4XES PAR2 5NDD
TM7 310 7.43x42 NTS1 receptor 4XES CCR5 5UIW
TM7 311 7.44x43 NTS1 receptor 4XES PAR2 5NDD
TM7 312 7.45x45 NTS1 receptor 4XES CXCR4 3ODU
TM7 313 7.46x46 NTS1 receptor 4XES PAR1 3VW7
TM7 314 7.47x47 NTS1 receptor 4XES PAF receptor 5ZKQ
TM7 315 7.48x48 NTS1 receptor 4XES NTS1 receptor 4XES
TM7 316 7.49x49 apelin receptor 5VBL apelin receptor 5VBL
TM7 317 7.50x50 apelin receptor 5VBL apelin receptor 5VBL
TM7 318 7.51x51 apelin receptor 5VBL P2Y1 receptor 4XNW
TM7 319 7.52x52 apelin receptor 5VBL apelin receptor 5VBL
TM7 320 7.53x53 apelin receptor 5VBL apelin receptor 5VBL
TM7 321 7.54x54 apelin receptor 5VBL NTS1 receptor 4BUO
TM7 322 7.55x55 apelin receptor 5VBL apelin receptor 5VBL
TM7 323 7.56x56 apelin receptor 5VBL PAF receptor 5ZKQ
H8 324 8.47x47 apelin receptor 5VBL PAR2 5NDD
H8 325 8.48x48 apelin receptor 5VBL apelin receptor 5VBL
H8 326 8.49x49 apelin receptor 5VBL - -
H8 327 8.50x50 apelin receptor 5VBL apelin receptor 5VBL
H8 328 8.51x51 apelin receptor 5VBL apelin receptor 5VBL
H8 329 8.52x52 apelin receptor 5VBL - -
H8 330 8.53x53 apelin receptor 5VBL - -
H8 331 8.54x54 apelin receptor 5VBL CCR9 5LWE
H8 332 8.55x55 apelin receptor 5VBL NTS1 receptor 4BUO
H8 333 8.56x56 apelin receptor 5VBL PAR2 5NDD
H8 334 8.57x57 apelin receptor 5VBL PAR2 5NDD
H8 335 8.58x58 apelin receptor 5VBL - -
H8 336 8.59x59 apelin receptor 5VBL - -
H8 337 8.60x60 apelin receptor 5VBL - -
H8 338 8.61x61 apelin receptor 5VBL - -
C-term 339 - - - -
C-term 340 - - - -
C-term 341 - - - -
C-term 342 - - - -
C-term 343 - - - -