GPR19 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): -1.14 docs)

VERSION

2018-07-10

MAIN TEMPLATE

OX2 receptor (sequence similarity: 49%) PDB: 5WS3

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 87.7 5.5 6.8
Side-chains 23.6 50.7 25.7

Number of backbone templates: 5
Number of rotamer templates: 37

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5WS3
4ZJ8
3SN6
4UHR
5WIV
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 59 OX2 receptor 5WS3 OX2 receptor 5WS3
N-term 60 OX2 receptor 5WS3 OX2 receptor 5WS3
N-term 61 OX2 receptor 5WS3 OX2 receptor 5WS3
N-term 62 OX2 receptor 5WS3 OX2 receptor 5WS3
N-term 63 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 64 1.31x31 OX2 receptor 5WS3 M4 receptor 5DSG
TM1 65 1.32x32 OX2 receptor 5WS3 M2 receptor 3UON
TM1 66 1.33x33 OX2 receptor 5WS3 D4 receptor 5WIV
TM1 67 1.34x34 OX2 receptor 5WS3 μ receptor 4DKL
TM1 68 1.35x35 OX2 receptor 5WS3 D4 receptor 5WIV
TM1 69 1.36x36 OX2 receptor 5WS3 S1P1 receptor 3V2Y
TM1 70 1.37x37 OX2 receptor 5WS3 β2-adrenoceptor 5JQH
TM1 71 1.38x38 OX2 receptor 5WS3 - -
TM1 72 1.39x39 OX2 receptor 5WS3 S1P1 receptor 3V2Y
TM1 73 1.40x40 OX2 receptor 5WS3 M2 receptor 3UON
TM1 74 1.41x41 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 75 1.42x42 OX2 receptor 5WS3 D2 receptor 6CM4
TM1 76 1.43x43 OX2 receptor 5WS3 - -
TM1 77 1.44x44 OX2 receptor 5WS3 D3 receptor 3PBL
TM1 78 1.45x45 OX2 receptor 5WS3 CCR5 5UIW
TM1 79 1.46x46 OX2 receptor 5WS3 A1 receptor 5UEN
TM1 80 1.47x47 OX2 receptor 5WS3 M2 receptor 3UON
TM1 81 1.48x48 OX2 receptor 5WS3 D2 receptor 6CM4
TM1 82 1.49x49 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 83 1.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 84 1.51x51 OX2 receptor 5WS3 D4 receptor 5WIV
TM1 85 1.52x52 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 86 1.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 87 1.54x54 OX2 receptor 5WS3 OX2 receptor 5WS3
TM1 88 1.55x55 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM1 89 1.56x56 OX2 receptor 5WS3 κ receptor 4DJH
TM1 90 1.57x57 OX2 receptor 5WS3 κ receptor 4DJH
TM1 91 1.58x58 OX2 receptor 5WS3 - -
TM1 92 1.59x59 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM1 93 1.60x60 OX2 receptor 5WS3 apelin receptor 5VBL
ICL1 94 12.48x48 OX2 receptor 5WS3 D3 receptor 3PBL
ICL1 95 12.49x49 OX2 receptor 5WS3 β2-adrenoceptor 5JQH
ICL1 96 12.50x50 OX2 receptor 5WS3 - -
ICL1 97 12.51x51 OX2 receptor 5WS3 D2 receptor 6CM4
TM2 98 2.37x37 OX2 receptor 5WS3 CCR5 5UIW
TM2 99 2.38x38 OX2 receptor 5WS3 D2 receptor 6CM4
TM2 100 2.39x39 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 101 2.40x40 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 102 2.41x41 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 103 2.42x42 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 104 2.43x43 OX2 receptor 5WS3 D3 receptor 3PBL
TM2 105 2.44x44 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 106 2.45x45 OX2 receptor 5WS3 D2 receptor 6CM4
TM2 107 2.46x46 OX2 receptor 5WS3 - -
TM2 108 2.47x47 OX2 receptor 5WS3 D2 receptor 6CM4
TM2 109 2.48x48 OX2 receptor 5WS3 M2 receptor 3UON
TM2 110 2.49x49 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 111 2.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 112 2.51x51 OX2 receptor 5WS3 D2 receptor 6CM4
TM2 113 2.52x52 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 114 2.53x53 OX2 receptor 5WS3 M2 receptor 3UON
TM2 115 2.54x54 OX2 receptor 5WS3 CB1 receptor 5TGZ
TM2 116 2.55x55 OX2 receptor 5WS3 M2 receptor 3UON
TM2 117 2.56x551 OX2 receptor 5WS3 β2-adrenoceptor 5JQH
TM2 118 2.57x56 OX2 receptor 5WS3 M2 receptor 3UON
TM2 119 2.58x57 OX2 receptor 5WS3 - -
TM2 120 2.59x58 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 121 2.60x59 OX2 receptor 5WS3 κ receptor 4DJH
TM2 122 2.61x60 OX2 receptor 5WS3 D2 receptor 6CM4
TM2 123 2.62x61 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 124 2.63x62 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM2 125 2.64x63 OX2 receptor 5WS3 - -
TM2 126 2.65x64 OX2 receptor 5WS3 NTS1 receptor 4BUO
TM2 127 2.66x65 OX2 receptor 5WS3 A2A receptor 3VG9
TM2 128 2.67x66 OX2 receptor 5WS3 OX2 receptor 5WS3
TM2 129 2.68x67 OX2 receptor 5WS3 D2 receptor 6CM4
ECL1 130 23.49x49 OX2 receptor 5WS3 AT1 receptor 4ZUD
ECL1 131 23.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL1 132 23.51x51 OX2 receptor 5WS3 β2-adrenoceptor 5JQH
ECL1 133 23.52x52 OX2 receptor 5WS3 M2 receptor 3UON
TM3 134 3.21x21 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 135 3.22x22 OX2 receptor 5WS3 LPA6 receptor 5XSZ
TM3 136 3.23x23 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM3 137 3.24x24 OX2 receptor 5WS3 A1 receptor 5UEN
TM3 138 3.25x25 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 139 3.26x26 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 140 3.27x27 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 141 3.28x28 OX2 receptor 5WS3 κ receptor 4DJH
TM3 142 3.29x29 OX2 receptor 5WS3 P2Y1 receptor 4XNW
TM3 143 3.30x30 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 144 3.31x31 OX2 receptor 5WS3 Rhodopsin 1GZM
TM3 145 3.32x32 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 146 3.33x33 OX2 receptor 5WS3 κ receptor 4DJH
TM3 147 3.34x34 OX2 receptor 5WS3 β2-adrenoceptor 5JQH
TM3 148 3.35x35 OX2 receptor 5WS3 P2Y12 receptor 4NTJ
TM3 149 3.36x36 OX2 receptor 5WS3 - -
TM3 150 3.37x37 OX2 receptor 5WS3 ETB receptor 5X93
TM3 151 3.38x38 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 152 3.39x39 OX2 receptor 5WS3 - -
TM3 153 3.40x40 OX2 receptor 5WS3 D3 receptor 3PBL
TM3 154 3.41x41 OX2 receptor 5WS3 - -
TM3 155 3.42x42 OX2 receptor 5WS3 - -
TM3 156 3.43x43 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 157 3.44x44 OX2 receptor 5WS3 M2 receptor 3UON
TM3 158 3.45x45 OX2 receptor 5WS3 NTS1 receptor 4BUO
TM3 159 3.46x46 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 160 3.47x47 OX2 receptor 5WS3 H1 receptor 3RZE
TM3 161 3.48x48 OX2 receptor 5WS3 D2 receptor 6CM4
TM3 162 3.49x49 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 163 3.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 164 3.51x51 OX2 receptor 5WS3 D4 receptor 5WIV
TM3 165 3.52x52 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 166 3.53x53 OX2 receptor 5WS3 S1P1 receptor 3V2Y
TM3 167 3.54x54 OX2 receptor 5WS3 OX2 receptor 5WS3
TM3 168 3.55x55 OX2 receptor 5WS3 D3 receptor 3PBL
TM3 169 3.56x56 OX2 receptor 5WS3 LPA6 receptor 5XSZ
ICL2 170 34.50x50 - - - -
ICL2 171 34.51x51 OX1 receptor 4ZJ8 OX1 receptor 4ZJ8
ICL2 172 34.52x52 OX1 receptor 4ZJ8 M1 receptor 5CXV
ICL2 173 34.53x53 OX1 receptor 4ZJ8 OX1 receptor 4ZJ8
ICL2 174 OX1 receptor 4ZJ8 OX1 receptor 4ZJ8
ICL2 175 - - - -
TM4 176 4.38x38 OX2 receptor 5WS3 D2 receptor 6CM4
TM4 177 4.39x39 OX2 receptor 5WS3 NTS1 receptor 4BUO
TM4 178 4.40x40 OX2 receptor 5WS3 - -
TM4 179 4.41x41 OX2 receptor 5WS3 κ receptor 4DJH
TM4 180 4.42x42 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 181 4.43x43 OX2 receptor 5WS3 κ receptor 4DJH
TM4 182 4.44x44 OX2 receptor 5WS3 NTS1 receptor 4BUO
TM4 183 4.45x45 OX2 receptor 5WS3 D2 receptor 6CM4
TM4 184 4.46x46 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 185 4.47x47 OX2 receptor 5WS3 M2 receptor 3UON
TM4 186 4.48x48 OX2 receptor 5WS3 D3 receptor 3PBL
TM4 187 4.49x49 OX2 receptor 5WS3 - -
TM4 188 4.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 189 4.51x51 OX2 receptor 5WS3 D2 receptor 6CM4
TM4 190 4.52x52 OX2 receptor 5WS3 5-HT1B receptor 4IAQ
TM4 191 4.53x53 OX2 receptor 5WS3 - -
TM4 192 4.54x54 OX2 receptor 5WS3 D4 receptor 5WIV
TM4 193 4.55x55 OX2 receptor 5WS3 δ receptor 4N6H
TM4 194 4.56x56 OX2 receptor 5WS3 - -
TM4 195 4.57x57 OX2 receptor 5WS3 PAR1 3VW7
TM4 196 4.58x59 OX2 receptor 5WS3 A2A receptor 3VG9
TM4 197 4.59x60 OX2 receptor 5WS3 OX2 receptor 5WS3
TM4 198 4.60x61 OX2 receptor 5WS3 D4 receptor 5WIV
TM4 199 4.61x62 OX2 receptor 5WS3 D2 receptor 6CM4
TM4 200 4.62x63 OX2 receptor 5WS3 D2 receptor 6CM4
TM4 201 4.63x64 OX2 receptor 5WS3 CCR5 5UIW
TM4 202 4.64x65 OX2 receptor 5WS3 - -
ECL2 203 - - - -
ECL2 204 - - - -
ECL2 205 - - - -
ECL2 206 - - - -
ECL2 207 - - - -
ECL2 208 - - - -
ECL2 209 - - - -
ECL2 210 45.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
ECL2 211 45.51x51 OX2 receptor 5WS3 - -
ECL2 212 45.52x52 OX2 receptor 5WS3 - -
ECL2 213 OX2 receptor 5WS3 - -
ECL2 214 OX2 receptor 5WS3 - -
ECL2 215 OX2 receptor 5WS3 - -
ECL2 216 OX2 receptor 5WS3 - -
ECL2 217 OX2 receptor 5WS3 - -
TM5 218 5.33x34 OX2 receptor 5WS3 κ receptor 4DJH
TM5 219 5.34x35 OX2 receptor 5WS3 - -
TM5 220 5.35x36 OX2 receptor 5WS3 NOP receptor 5DHG
TM5 221 5.36x37 OX2 receptor 5WS3 H1 receptor 3RZE
TM5 222 5.37x38 OX2 receptor 5WS3 D2 receptor 6CM4
TM5 223 5.38x39 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 224 5.39x40 OX2 receptor 5WS3 M2 receptor 3UON
TM5 225 5.40x41 OX2 receptor 5WS3 D2 receptor 6CM4
TM5 226 5.41x42 OX2 receptor 5WS3 5-HT2C receptor 6BQH
TM5 227 5.42x43 OX2 receptor 5WS3 CXCR4 3ODU
TM5 228 5.43x44 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 229 5.44x45 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 230 5.45x46 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 231 5.46x461 OX2 receptor 5WS3 CCR5 5UIW
TM5 232 5.47x47 OX2 receptor 5WS3 D2 receptor 6CM4
TM5 233 5.48x48 OX2 receptor 5WS3 κ receptor 4DJH
TM5 234 5.49x49 OX2 receptor 5WS3 κ receptor 4DJH
TM5 235 5.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 236 5.51x51 OX2 receptor 5WS3 - -
TM5 237 5.52x52 OX2 receptor 5WS3 M4 receptor 5DSG
TM5 238 5.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 239 5.54x54 OX2 receptor 5WS3 κ receptor 4DJH
TM5 240 5.55x55 OX2 receptor 5WS3 κ receptor 4DJH
TM5 241 5.56x56 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 242 5.57x57 OX2 receptor 5WS3 H1 receptor 3RZE
TM5 243 5.58x58 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 244 5.59x59 OX2 receptor 5WS3 - -
TM5 245 5.60x60 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM5 246 5.61x61 OX2 receptor 5WS3 β2-adrenoceptor 5JQH
TM5 247 5.62x62 OX2 receptor 5WS3 κ receptor 4DJH
TM5 248 5.63x63 OX2 receptor 5WS3 H1 receptor 3RZE
TM5 249 5.64x64 OX2 receptor 5WS3 LPA1 receptor 4Z35
TM5 250 5.65x65 OX2 receptor 5WS3 apelin receptor 5VBL
TM5 251 5.66x66 OX2 receptor 5WS3 OX2 receptor 5WS3
TM5 252 5.67x67 OX2 receptor 5WS3 D4 receptor 5WIV
TM5 253 5.68x68 β2-adrenoceptor 3SN6 - -
TM5 254 5.69x69 β2-adrenoceptor 3SN6 - -
TM5 255 5.70x70 β2-adrenoceptor 3SN6 - -
TM5 256 5.71x71 β2-adrenoceptor 3SN6 - -
TM5 257 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 258 5.73x73 β2-adrenoceptor 3SN6 - -
ICL3 259 - - - -
ICL3 260 - - - -
ICL3 261 - - - -
ICL3 262 - - - -
TM6 263 6.22x22 A2A receptor 4UHR - -
TM6 264 6.23x23 A2A receptor 4UHR - -
TM6 265 6.24x24 A2A receptor 4UHR - -
TM6 266 6.25x25 OX2 receptor 5WS3 - -
TM6 267 6.26x26 OX2 receptor 5WS3 - -
TM6 268 6.27x27 OX2 receptor 5WS3 - -
TM6 269 6.28x28 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 270 6.29x29 OX2 receptor 5WS3 LPA1 receptor 4Z35
TM6 271 6.30x30 OX2 receptor 5WS3 CCR9 5LWE
TM6 272 6.31x31 OX2 receptor 5WS3 A2A receptor 3VG9
TM6 273 6.32x32 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 274 6.33x33 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 275 6.34x34 OX2 receptor 5WS3 - -
TM6 276 6.35x35 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM6 277 6.36x36 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 278 6.37x37 OX2 receptor 5WS3 - -
TM6 279 6.38x38 OX2 receptor 5WS3 κ receptor 4DJH
TM6 280 6.39x39 OX2 receptor 5WS3 D2 receptor 6CM4
TM6 281 6.40x40 OX2 receptor 5WS3 apelin receptor 5VBL
TM6 282 6.41x41 OX2 receptor 5WS3 - -
TM6 283 6.42x42 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 284 6.43x43 OX2 receptor 5WS3 A2A receptor 3VG9
TM6 285 6.44x44 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 286 6.45x45 OX2 receptor 5WS3 D4 receptor 5WIV
TM6 287 6.46x46 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM6 288 6.47x47 OX2 receptor 5WS3 CCR9 5LWE
TM6 289 6.48x48 OX2 receptor 5WS3 D2 receptor 6CM4
TM6 290 6.49x49 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 291 6.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM6 292 6.51x51 OX2 receptor 5WS3 D2 receptor 6CM4
TM6 293 6.52x52 OX2 receptor 5WS3 κ receptor 4DJH
TM6 294 6.53x53 OX2 receptor 5WS3 OX1 receptor 4ZJ8
TM6 295 6.54x54 OX2 receptor 5WS3 ETB receptor 5X93
TM6 296 6.55x55 OX2 receptor 5WS3 PAF receptor 5ZKP
TM6 297 6.56x56 OX2 receptor 5WS3 κ receptor 4DJH
TM6 298 6.57x57 OX2 receptor 5WS3 - -
TM6 299 6.58x58 OX2 receptor 5WS3 β2-adrenoceptor 5JQH
TM6 300 6.59x59 OX2 receptor 5WS3 5-HT1B receptor 4IAQ
TM6 301 6.60x60 OX2 receptor 5WS3 - -
TM6 302 6.61x61 OX2 receptor 5WS3 - -
ECL3 303 - - - -
ECL3 304 D4 receptor 5WIV - -
ECL3 305 D4 receptor 5WIV - -
ECL3 306 D4 receptor 5WIV - -
ECL3 307 - - - -
TM7 308 7.31x30 OX2 receptor 5WS3 - -
TM7 309 7.32x31 OX2 receptor 5WS3 A1 receptor 5UEN
TM7 310 7.33x32 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM7 311 7.34x33 OX2 receptor 5WS3 M2 receptor 3UON
TM7 312 7.35x34 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 313 7.36x35 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 314 7.37x36 OX2 receptor 5WS3 D2 receptor 6CM4
TM7 315 7.38x37 OX2 receptor 5WS3 - -
TM7 316 7.39x38 OX2 receptor 5WS3 D2 receptor 6CM4
TM7 317 7.40x39 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 318 7.41x40 OX2 receptor 5WS3 β2-adrenoceptor 5JQH
TM7 319 7.42x41 OX2 receptor 5WS3 A2A receptor 3VG9
TM7 320 7.43x42 OX2 receptor 5WS3 CCR9 5LWE
TM7 321 7.44x43 OX2 receptor 5WS3 Rhodopsin 4ZWJ
TM7 322 7.45x45 OX2 receptor 5WS3 Y1 receptor 5ZBH
TM7 323 7.46x46 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 324 7.47x47 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 325 7.48x48 OX2 receptor 5WS3 - -
TM7 326 7.49x49 OX2 receptor 5WS3 - -
TM7 327 7.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 328 7.51x51 OX2 receptor 5WS3 - -
TM7 329 7.52x52 OX2 receptor 5WS3 κ receptor 4DJH
TM7 330 7.53x53 OX2 receptor 5WS3 OX2 receptor 5WS3
TM7 331 7.54x54 OX2 receptor 5WS3 LPA1 receptor 4Z35
TM7 332 7.55x55 OX2 receptor 5WS3 - -
TM7 333 7.56x56 OX2 receptor 5WS3 - -
H8 334 8.47x47 OX2 receptor 5WS3 D2 receptor 6CM4
H8 335 8.48x48 OX2 receptor 5WS3 D4 receptor 5WIV
H8 336 8.49x49 OX2 receptor 5WS3 κ receptor 4DJH
H8 337 8.50x50 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 338 8.51x51 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 339 8.52x52 OX2 receptor 5WS3 κ receptor 4DJH
H8 340 8.53x53 OX2 receptor 5WS3 - -
H8 341 8.54x54 OX2 receptor 5WS3 Rhodopsin 1GZM
H8 342 8.55x55 OX2 receptor 5WS3 OX2 receptor 5WS3
H8 343 8.56x56 OX2 receptor 5WS3 β2-adrenoceptor 2RH1
H8 344 8.57x57 OX2 receptor 5WS3 Rhodopsin 1GZM
H8 345 8.58x58 OX2 receptor 5WS3 OX2 receptor 5WS3
C-term 346 - - - -
C-term 347 - - - -
C-term 348 - - - -
C-term 349 - - - -
C-term 350 - - - -