GPR1 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 10.15 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 48%) PDB: 5C1M

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 78.1 10.4 11.4
Side-chains 27.3 48.5 24.2

Number of backbone templates: 4
Number of rotamer templates: 38

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5C1M
4DKL
5O9H
5VBL
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 31 μ receptor 5C1M μ receptor 5C1M
N-term 32 μ receptor 5C1M μ receptor 5C1M
N-term 33 μ receptor 5C1M μ receptor 5C1M
N-term 34 μ receptor 5C1M μ receptor 5C1M
N-term 35 μ receptor 5C1M μ receptor 5C1M
TM1 36 1.30x30 μ receptor 5C1M μ receptor 5C1M
TM1 37 1.31x31 μ receptor 5C1M LPA1 receptor 4Z35
TM1 38 1.32x32 μ receptor 5C1M - -
TM1 39 1.33x33 μ receptor 5C1M OX2 receptor 5WS3
TM1 40 1.34x34 μ receptor 5C1M US28 4XT1
TM1 41 1.35x35 μ receptor 5C1M FFA1 receptor 5TZY
TM1 42 1.36x36 μ receptor 5C1M US28 4XT1
TM1 43 1.37x37 μ receptor 5C1M CB1 receptor 5XRA
TM1 44 1.38x38 μ receptor 5C1M μ receptor 5C1M
TM1 45 1.39x39 μ receptor 5C1M μ receptor 5C1M
TM1 46 1.40x40 μ receptor 5C1M ETB receptor 5X93
TM1 47 1.41x41 μ receptor 5C1M Rhodopsin 5DYS
TM1 48 1.42x42 μ receptor 5C1M FFA1 receptor 5TZY
TM1 49 1.43x43 μ receptor 5C1M AT2 receptor 5UNG
TM1 50 1.44x44 μ receptor 5C1M μ receptor 5C1M
TM1 51 1.45x45 μ receptor 5C1M Rhodopsin 5DYS
TM1 52 1.46x46 μ receptor 5C1M μ receptor 5C1M
TM1 53 1.47x47 μ receptor 5C1M 5-HT2B receptor 5TUD
TM1 54 1.48x48 μ receptor 5C1M Rhodopsin 5DYS
TM1 55 1.49x49 μ receptor 5C1M μ receptor 5C1M
TM1 56 1.50x50 μ receptor 5C1M μ receptor 5C1M
TM1 57 1.51x51 μ receptor 5C1M 5-HT1B receptor 6G79
TM1 58 1.52x52 μ receptor 5C1M - -
TM1 59 1.53x53 μ receptor 5C1M μ receptor 5C1M
TM1 60 1.54x54 μ receptor 5C1M US28 4XT1
TM1 61 1.55x55 μ receptor 5C1M PAF receptor 5ZKP
TM1 62 1.56x56 μ receptor 5C1M - -
TM1 63 1.57x57 μ receptor 5C1M Rhodopsin 5DYS
TM1 64 1.58x58 μ receptor 5C1M CXCR4 3ODU
TM1 65 1.59x59 μ receptor 5C1M C5a1 receptor 5O9H
TM1 66 1.60x60 μ receptor 5C1M PAR1 3VW7
ICL1 67 - - - -
ICL1 68 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL1 69 - - - -
TM2 70 2.37x37 μ receptor 5C1M μ receptor 5C1M
TM2 71 2.38x38 μ receptor 5C1M AT2 receptor 5UNG
TM2 72 2.39x39 μ receptor 5C1M μ receptor 5C1M
TM2 73 2.40x40 μ receptor 5C1M LPA6 receptor 5XSZ
TM2 74 2.41x41 μ receptor 5C1M BLT1 receptor 5X33
TM2 75 2.42x42 μ receptor 5C1M C5a1 receptor 5O9H
TM2 76 2.43x43 μ receptor 5C1M US28 4XT1
TM2 77 2.44x44 μ receptor 5C1M Rhodopsin 5DYS
TM2 78 2.45x45 μ receptor 5C1M μ receptor 5C1M
TM2 79 2.46x46 μ receptor 5C1M μ receptor 5C1M
TM2 80 2.47x47 μ receptor 5C1M μ receptor 5C1M
TM2 81 2.48x48 μ receptor 5C1M 5-HT2C receptor 6BQG
TM2 82 2.49x49 μ receptor 5C1M μ receptor 5C1M
TM2 83 2.50x50 μ receptor 5C1M μ receptor 5C1M
TM2 84 2.51x51 μ receptor 5C1M C5a1 receptor 5O9H
TM2 85 2.52x52 μ receptor 5C1M M2 receptor 4MQT
TM2 86 2.53x53 μ receptor 5C1M LPA6 receptor 5XSZ
TM2 87 2.54x54 μ receptor 5C1M AT2 receptor 5UNG
TM2 88 2.55x55 μ receptor 5C1M LPA6 receptor 5XSZ
TM2 89 2.56x56 μ receptor 5C1M - -
TM2 90 2.57x57 μ receptor 5C1M μ receptor 5C1M
TM2 91 2.58x58 μ receptor 5C1M μ receptor 5C1M
TM2 92 2.59x59 μ receptor 5C1M AT2 receptor 5UNG
TM2 93 2.60x60 μ receptor 5C1M M2 receptor 4MQT
TM2 94 2.61x61 μ receptor 5C1M PAF receptor 5ZKP
TM2 95 2.62x62 μ receptor 5C1M PAR1 3VW7
TM2 96 2.63x63 μ receptor 5C1M AT2 receptor 5UNG
TM2 97 2.64x64 μ receptor 5C1M - -
TM2 98 2.65x65 μ receptor 5C1M AT1 receptor 4ZUD
TM2 99 2.66x66 μ receptor 5C1M μ receptor 5C1M
ECL1 100 - - - -
ECL1 101 - - - -
ECL1 102 23.49x49 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 103 23.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 104 23.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
ECL1 105 23.52x52 - - - -
TM3 106 3.21x21 μ receptor 5C1M μ receptor 5C1M
TM3 107 3.22x22 μ receptor 5C1M - -
TM3 108 3.23x23 μ receptor 5C1M - -
TM3 109 3.24x24 μ receptor 5C1M μ receptor 5C1M
TM3 110 3.25x25 μ receptor 5C1M μ receptor 5C1M
TM3 111 3.26x26 μ receptor 5C1M μ receptor 5C1M
TM3 112 3.27x27 μ receptor 5C1M 5-HT2B receptor 5TUD
TM3 113 3.28x28 μ receptor 5C1M Y1 receptor 5ZBH
TM3 114 3.29x29 μ receptor 5C1M AT1 receptor 4ZUD
TM3 115 3.30x30 μ receptor 5C1M Rhodopsin 5DYS
TM3 116 3.31x31 μ receptor 5C1M - -
TM3 117 3.32x32 μ receptor 5C1M Rhodopsin 5DYS
TM3 118 3.33x33 μ receptor 5C1M - -
TM3 119 3.34x34 μ receptor 5C1M AT2 receptor 5UNG
TM3 120 3.35x35 μ receptor 5C1M μ receptor 5C1M
TM3 121 3.36x36 μ receptor 5C1M μ receptor 5C1M
TM3 122 3.37x37 μ receptor 5C1M μ receptor 5C1M
TM3 123 3.38x38 μ receptor 5C1M AT2 receptor 5UNG
TM3 124 3.39x39 μ receptor 5C1M μ receptor 5C1M
TM3 125 3.40x40 μ receptor 5C1M M2 receptor 4MQT
TM3 126 3.41x41 μ receptor 5C1M μ receptor 5C1M
TM3 127 3.42x42 μ receptor 5C1M AT2 receptor 5UNG
TM3 128 3.43x43 μ receptor 5C1M μ receptor 5C1M
TM3 129 3.44x44 μ receptor 5C1M AT2 receptor 5UNG
TM3 130 3.45x45 μ receptor 5C1M Rhodopsin 5DYS
TM3 131 3.46x46 μ receptor 5C1M LPA6 receptor 5XSZ
TM3 132 3.47x47 μ receptor 5C1M μ receptor 5C1M
TM3 133 3.48x48 μ receptor 5C1M US28 4XT1
TM3 134 3.49x49 μ receptor 5C1M μ receptor 5C1M
TM3 135 3.50x50 μ receptor 5C1M - -
TM3 136 3.51x51 μ receptor 5C1M μ receptor 5C1M
TM3 137 3.52x52 μ receptor 5C1M μ receptor 5C1M
TM3 138 3.53x53 μ receptor 5C1M - -
TM3 139 3.54x54 μ receptor 5C1M - -
TM3 140 3.55x55 μ receptor 5C1M AT2 receptor 5UNG
TM3 141 3.56x56 μ receptor 5C1M μ receptor 5C1M
ICL2 142 34.50x50 - - - -
ICL2 143 34.51x51 C5a1 receptor 5O9H μ receptor 5C1M
ICL2 144 34.52x52 C5a1 receptor 5O9H BLT1 receptor 5X33
ICL2 145 34.53x53 C5a1 receptor 5O9H LPA6 receptor 5XSZ
ICL2 146 34.54x54 C5a1 receptor 5O9H CCR9 5LWE
ICL2 147 34.55x55 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 148 34.56x56 C5a1 receptor 5O9H - -
ICL2 149 34.57x57 - - - -
TM4 150 4.38x38 μ receptor 5C1M μ receptor 5C1M
TM4 151 4.39x39 μ receptor 5C1M CXCR4 3ODU
TM4 152 4.40x40 μ receptor 5C1M US28 4XT1
TM4 153 4.41x41 μ receptor 5C1M μ receptor 5C1M
TM4 154 4.42x42 μ receptor 5C1M CCR9 5LWE
TM4 155 4.43x43 μ receptor 5C1M D4 receptor 5WIV
TM4 156 4.44x44 μ receptor 5C1M μ receptor 5C1M
TM4 157 4.45x45 μ receptor 5C1M μ receptor 5C1M
TM4 158 4.46x46 μ receptor 5C1M 5-HT2B receptor 5TUD
TM4 159 4.47x47 μ receptor 5C1M κ receptor 6B73
TM4 160 4.48x48 μ receptor 5C1M US28 4XT1
TM4 161 4.49x49 μ receptor 5C1M κ receptor 6B73
TM4 162 4.50x50 μ receptor 5C1M μ receptor 5C1M
TM4 163 4.51x51 μ receptor 5C1M κ receptor 6B73
TM4 164 4.52x52 μ receptor 5C1M μ receptor 5C1M
TM4 165 4.53x53 μ receptor 5C1M AT2 receptor 5UNG
TM4 166 4.54x54 μ receptor 5C1M μ receptor 5C1M
TM4 167 4.55x55 μ receptor 5C1M AT2 receptor 5UNG
TM4 168 4.56x56 μ receptor 5C1M μ receptor 5C1M
TM4 169 4.57x57 μ receptor 5C1M μ receptor 5C1M
TM4 170 4.58x58 μ receptor 5C1M S1P1 receptor 3V2Y
TM4 171 4.59x59 μ receptor 5C1M μ receptor 5C1M
TM4 172 4.60x60 μ receptor 5C1M κ receptor 6B73
TM4 173 4.61x61 μ receptor 5C1M Rhodopsin 5DYS
TM4 174 4.62x62 μ receptor 5C1M PAR2 5NDD
TM4 175 4.63x63 μ receptor 5C1M NTS1 receptor 5T04
TM4 176 4.64x64 μ receptor 5C1M - -
ECL2 177 μ receptor 5C1M - -
ECL2 178 μ receptor 5C1M μ receptor 5C1M
ECL2 179 μ receptor 5C1M - -
ECL2 180 μ receptor 5C1M - -
ECL2 181 μ receptor 5C1M - -
ECL2 182 μ receptor 5C1M - -
ECL2 183 μ receptor 5C1M - -
ECL2 184 μ receptor 5C1M - -
ECL2 185 μ receptor 5C1M - -
ECL2 186 μ receptor 5C1M - -
ECL2 187 45.50x50 μ receptor 5C1M μ receptor 5C1M
ECL2 188 45.51x51 μ receptor 5C1M M2 receptor 4MQT
ECL2 189 45.52x52 μ receptor 5C1M - -
ECL2 190 - - - -
ECL2 191 - - - -
ECL2 192 - - - -
ECL2 193 - - - -
ECL2 194 - - - -
ECL2 195 - - - -
ECL2 196 - - - -
ECL2 197 - - - -
ECL2 198 - - - -
ECL2 199 - - - -
ECL2 200 - - - -
ECL2 201 - - - -
TM5 202 5.34x35 μ receptor 5C1M C5a1 receptor 5O9H
TM5 203 5.35x36 μ receptor 5C1M P2Y12 receptor 4NTJ
TM5 204 5.36x37 μ receptor 5C1M - -
TM5 205 5.37x38 μ receptor 5C1M NTS1 receptor 5T04
TM5 206 5.38x39 μ receptor 5C1M μ receptor 5C1M
TM5 207 5.39x40 μ receptor 5C1M M2 receptor 4MQT
TM5 208 5.40x41 μ receptor 5C1M ETB receptor 5X93
TM5 209 5.41x42 μ receptor 5C1M NTS1 receptor 5T04
TM5 210 5.42x43 μ receptor 5C1M AT2 receptor 5UNG
TM5 211 5.43x44 μ receptor 5C1M μ receptor 5C1M
TM5 212 5.44x45 μ receptor 5C1M μ receptor 5C1M
TM5 213 5.45x46 μ receptor 5C1M H1 receptor 3RZE
TM5 214 5.46x461 μ receptor 5C1M AT2 receptor 5UNG
TM5 215 5.47x47 μ receptor 5C1M OX2 receptor 5WS3
TM5 216 5.48x48 μ receptor 5C1M LPA6 receptor 5XSZ
TM5 217 5.49x49 μ receptor 5C1M NTS1 receptor 5T04
TM5 218 5.50x50 μ receptor 5C1M μ receptor 5C1M
TM5 219 5.51x51 μ receptor 5C1M AT2 receptor 5UNG
TM5 220 5.52x52 μ receptor 5C1M μ receptor 5C1M
TM5 221 5.53x53 μ receptor 5C1M C5a1 receptor 5O9H
TM5 222 5.54x54 μ receptor 5C1M 5-HT2B receptor 5TUD
TM5 223 5.55x55 μ receptor 5C1M US28 4XT1
TM5 224 5.56x56 μ receptor 5C1M 5-HT2C receptor 6BQG
TM5 225 5.57x57 μ receptor 5C1M μ receptor 5C1M
TM5 226 5.58x58 μ receptor 5C1M μ receptor 5C1M
TM5 227 5.59x59 μ receptor 5C1M PAF receptor 5ZKP
TM5 228 5.60x60 μ receptor 5C1M - -
TM5 229 5.61x61 μ receptor 5C1M Rhodopsin 5DYS
TM5 230 5.62x62 μ receptor 5C1M μ receptor 5C1M
TM5 231 5.63x63 μ receptor 5C1M Rhodopsin 5DYS
TM5 232 5.64x64 μ receptor 5C1M NTS1 receptor 5T04
TM5 233 5.65x65 μ receptor 5C1M US28 4XT1
TM5 234 5.66x66 μ receptor 5C1M μ receptor 5C1M
TM5 235 5.67x67 μ receptor 5C1M AT2 receptor 5UNG
TM5 236 5.68x68 μ receptor 5C1M C5a1 receptor 6C1R
ICL3 237 - - - -
ICL3 238 - - - -
ICL3 239 - - - -
ICL3 240 - - - -
TM6 241 6.30x30 μ receptor 5C1M C5a1 receptor 6C1R
TM6 242 6.31x31 μ receptor 5C1M - -
TM6 243 6.32x32 μ receptor 5C1M μ receptor 5C1M
TM6 244 6.33x33 μ receptor 5C1M - -
TM6 245 6.34x34 μ receptor 5C1M AT1 receptor 4ZUD
TM6 246 6.35x35 μ receptor 5C1M - -
TM6 247 6.36x36 μ receptor 5C1M β2-adrenoceptor 3SN6
TM6 248 6.37x37 μ receptor 5C1M LPA6 receptor 5XSZ
TM6 249 6.38x38 μ receptor 5C1M μ receptor 5C1M
TM6 250 6.39x39 μ receptor 5C1M μ receptor 5C1M
TM6 251 6.40x40 μ receptor 5C1M μ receptor 5C1M
TM6 252 6.41x41 μ receptor 5C1M μ receptor 5C1M
TM6 253 6.42x42 μ receptor 5C1M CB1 receptor 5XRA
TM6 254 6.43x43 μ receptor 5C1M AT2 receptor 5UNG
TM6 255 6.44x44 μ receptor 5C1M μ receptor 5C1M
TM6 256 6.45x45 μ receptor 5C1M κ receptor 6B73
TM6 257 6.46x46 μ receptor 5C1M μ receptor 5C1M
TM6 258 6.47x47 μ receptor 5C1M μ receptor 5C1M
TM6 259 6.48x48 μ receptor 5C1M μ receptor 5C1M
TM6 260 6.49x49 μ receptor 5C1M μ receptor 5C1M
TM6 261 6.50x50 μ receptor 5C1M μ receptor 5C1M
TM6 262 6.51x51 μ receptor 5C1M LPA6 receptor 5XSZ
TM6 263 6.52x52 μ receptor 5C1M μ receptor 5C1M
TM6 264 6.53x53 μ receptor 5C1M US28 4XT1
TM6 265 6.54x54 μ receptor 5C1M κ receptor 6B73
TM6 266 6.55x55 μ receptor 5C1M 5-HT1B receptor 6G79
TM6 267 6.56x56 μ receptor 5C1M μ receptor 5C1M
TM6 268 6.57x57 μ receptor 5C1M - -
TM6 269 6.58x58 μ receptor 5C1M κ receptor 4DJH
TM6 270 6.59x59 μ receptor 5C1M A1 receptor 6D9H
TM6 271 6.60x60 μ receptor 5C1M Rhodopsin 5DYS
TM6 272 6.61x61 μ receptor 5C1M μ receptor 5C1M
ECL3 273 - - - -
ECL3 274 - - - -
ECL3 275 - - - -
ECL3 276 - - - -
ECL3 277 - - - -
ECL3 278 - - - -
TM7 279 7.28x27 μ receptor 5C1M - -
TM7 280 7.29x28 μ receptor 5C1M - -
TM7 281 7.30x29 μ receptor 5C1M AT2 receptor 5UNG
TM7 282 7.31x30 μ receptor 5C1M 5-HT2C receptor 6BQG
TM7 283 7.32x31 μ receptor 5C1M 5-HT2B receptor 5TUD
TM7 284 7.33x32 μ receptor 5C1M 5-HT1B receptor 6G79
TM7 285 7.34x33 μ receptor 5C1M - -
TM7 286 7.35x34 μ receptor 5C1M CXCR4 3ODU
TM7 287 7.36x35 μ receptor 5C1M AT2 receptor 5UNG
TM7 288 7.37x36 μ receptor 5C1M US28 4XT1
TM7 289 7.38x37 μ receptor 5C1M OX2 receptor 5WS3
TM7 290 7.39x38 μ receptor 5C1M 5-HT1B receptor 6G79
TM7 291 7.40x39 μ receptor 5C1M P2Y1 receptor 4XNW
TM7 292 7.41x40 μ receptor 5C1M μ receptor 5C1M
TM7 293 7.42x41 μ receptor 5C1M LPA6 receptor 5XSZ
TM7 294 7.43x42 μ receptor 5C1M AT2 receptor 5UNG
TM7 295 7.44x43 μ receptor 5C1M CB1 receptor 5XRA
TM7 296 7.45x45 μ receptor 5C1M μ receptor 5C1M
TM7 297 7.46x46 μ receptor 5C1M μ receptor 5C1M
TM7 298 7.47x47 μ receptor 5C1M μ receptor 5C1M
TM7 299 7.48x48 μ receptor 5C1M μ receptor 5C1M
TM7 300 7.49x49 μ receptor 5C1M μ receptor 5C1M
TM7 301 7.50x50 μ receptor 5C1M μ receptor 5C1M
TM7 302 7.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 303 7.52x52 C5a1 receptor 5O9H AT2 receptor 5UNG
TM7 304 7.53x53 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 305 7.54x54 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 306 7.55x55 C5a1 receptor 5O9H 5-HT2B receptor 5TUD
TM7 307 7.56x56 C5a1 receptor 5O9H - -
H8 308 8.47x47 μ receptor 4DKL β2-adrenoceptor 3SN6
H8 309 8.48x48 μ receptor 4DKL Rhodopsin 5DYS
H8 310 8.49x49 μ receptor 4DKL A1 receptor 6D9H
H8 311 8.50x50 μ receptor 4DKL μ receptor 4DKL
H8 312 8.51x51 μ receptor 4DKL AT2 receptor 5UNF
H8 313 8.52x52 μ receptor 4DKL NOP receptor 5DHG
H8 314 8.53x53 μ receptor 4DKL - -
H8 315 8.54x54 μ receptor 4DKL μ receptor 4DKL
H8 316 8.55x55 μ receptor 4DKL A2A receptor 5G53
H8 317 8.56x56 μ receptor 4DKL AT2 receptor 5UNG
H8 318 8.57x57 μ receptor 4DKL - -
H8 319 8.58x58 μ receptor 4DKL - -
H8 320 8.59x59 μ receptor 4DKL US28 4XT1
H8 321 8.60x60 apelin receptor 5VBL US28 4XT1
H8 322 8.61x61 apelin receptor 5VBL - -
C-term 323 - - - -
C-term 324 - - - -
C-term 325 - - - -
C-term 326 - - - -
C-term 327 - - - -