GPR33 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate (Δ distance (Å): 7.2 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 44%) PDB: 6DDE

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 73.4 14.3 12.3
Side-chains 17.6 56.5 25.9

Number of backbone templates: 6
Number of rotamer templates: 36

NGL is a WebGL based 3D viewer powered by MMTF.

4ZUD
6DDE
4DKL
5O9H
5DYS
5VBL
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 22 AT1 receptor 4ZUD AT1 receptor 4ZUD
N-term 23 AT1 receptor 4ZUD AT1 receptor 4ZUD
N-term 24 AT1 receptor 4ZUD AT1 receptor 4ZUD
N-term 25 AT1 receptor 4ZUD AT1 receptor 4ZUD
N-term 26 AT1 receptor 4ZUD AT1 receptor 4ZUD
TM1 27 1.30x30 AT1 receptor 4ZUD κ receptor 4DJH
TM1 28 1.31x31 μ receptor 6DDE NTS1 receptor 4XES
TM1 29 1.32x32 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 30 1.33x33 μ receptor 6DDE - -
TM1 31 1.34x34 μ receptor 6DDE κ receptor 4DJH
TM1 32 1.35x35 μ receptor 6DDE AT1 receptor 4ZUD
TM1 33 1.36x36 μ receptor 6DDE 5-HT2B receptor 4IB4
TM1 34 1.37x37 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 35 1.38x38 μ receptor 6DDE D3 receptor 3PBL
TM1 36 1.39x39 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 37 1.40x40 μ receptor 6DDE AT2 receptor 5UNG
TM1 38 1.41x41 μ receptor 6DDE μ receptor 6DDE
TM1 39 1.42x42 μ receptor 6DDE BLT1 receptor 5X33
TM1 40 1.43x43 μ receptor 6DDE M4 receptor 5DSG
TM1 41 1.44x44 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 42 1.45x45 μ receptor 6DDE P2Y1 receptor 4XNW
TM1 43 1.46x46 μ receptor 6DDE μ receptor 6DDE
TM1 44 1.47x47 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM1 45 1.48x48 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 46 1.49x49 μ receptor 6DDE P2Y12 receptor 4NTJ
TM1 47 1.50x50 μ receptor 6DDE μ receptor 6DDE
TM1 48 1.51x51 μ receptor 6DDE PAR2 5NDD
TM1 49 1.52x52 μ receptor 6DDE μ receptor 6DDE
TM1 50 1.53x53 μ receptor 6DDE - -
TM1 51 1.54x54 μ receptor 6DDE PAR2 5NDD
TM1 52 1.55x55 μ receptor 6DDE PAR2 5NDD
TM1 53 1.56x56 μ receptor 6DDE μ receptor 6DDE
TM1 54 1.57x57 μ receptor 6DDE NTS1 receptor 4XES
TM1 55 1.58x58 μ receptor 6DDE H1 receptor 3RZE
TM1 56 1.59x59 μ receptor 6DDE PAR2 5NDD
TM1 57 1.60x60 μ receptor 6DDE NTS1 receptor 4XES
ICL1 58 - - - -
ICL1 59 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL1 60 - - - -
TM2 61 2.37x37 AT1 receptor 4ZUD AT1 receptor 4ZUD
TM2 62 2.38x38 μ receptor 6DDE A2A receptor 4UHR
TM2 63 2.39x39 μ receptor 6DDE C5a1 receptor 5O9H
TM2 64 2.40x40 μ receptor 6DDE LPA6 receptor 5XSZ
TM2 65 2.41x41 μ receptor 6DDE BLT1 receptor 5X33
TM2 66 2.42x42 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM2 67 2.43x43 μ receptor 6DDE C5a1 receptor 5O9H
TM2 68 2.44x44 μ receptor 6DDE μ receptor 6DDE
TM2 69 2.45x45 μ receptor 6DDE PAR1 3VW7
TM2 70 2.46x46 μ receptor 6DDE μ receptor 6DDE
TM2 71 2.47x47 μ receptor 6DDE - -
TM2 72 2.48x48 μ receptor 6DDE μ receptor 6DDE
TM2 73 2.49x49 μ receptor 6DDE NTS1 receptor 4XES
TM2 74 2.50x50 μ receptor 6DDE - -
TM2 75 2.51x51 μ receptor 6DDE P2Y1 receptor 4XNW
TM2 76 2.52x52 μ receptor 6DDE H1 receptor 3RZE
TM2 77 2.53x53 μ receptor 6DDE PAR2 5NDD
TM2 78 2.54x54 μ receptor 6DDE FFA1 receptor 5TZY
TM2 79 2.55x55 μ receptor 6DDE - -
TM2 80 2.56x56 μ receptor 6DDE CB1 receptor 5XRA
TM2 81 2.57x57 μ receptor 6DDE μ receptor 6DDE
TM2 82 2.58x58 μ receptor 6DDE μ receptor 6DDE
TM2 83 2.59x59 μ receptor 6DDE μ receptor 6DDE
TM2 84 2.60x60 μ receptor 6DDE - -
TM2 85 2.61x61 μ receptor 6DDE FFA1 receptor 5TZY
TM2 86 2.62x62 μ receptor 6DDE A2A receptor 3QAK
TM2 87 2.63x63 μ receptor 6DDE P2Y12 receptor 4NTJ
TM2 88 2.64x64 μ receptor 6DDE - -
TM2 89 2.65x65 μ receptor 6DDE FFA1 receptor 5TZY
TM2 90 2.66x66 μ receptor 6DDE C5a1 receptor 5O9H
ECL1 91 - - - -
ECL1 92 AT1 receptor 4ZUD - -
ECL1 93 23.49x49 AT1 receptor 4ZUD C5a1 receptor 5O9H
ECL1 94 23.50x50 AT1 receptor 4ZUD AT1 receptor 4ZUD
ECL1 95 23.51x51 AT1 receptor 4ZUD D3 receptor 3PBL
ECL1 96 23.52x52 - - - -
TM3 97 3.21x21 μ receptor 6DDE μ receptor 6DDE
TM3 98 3.22x22 μ receptor 6DDE P2Y12 receptor 4NTJ
TM3 99 3.23x23 μ receptor 6DDE PAR2 5NDD
TM3 100 3.24x24 μ receptor 6DDE μ receptor 6DDE
TM3 101 3.25x25 μ receptor 6DDE μ receptor 6DDE
TM3 102 3.26x26 μ receptor 6DDE μ receptor 6DDE
TM3 103 3.27x27 μ receptor 6DDE PAR2 5NDD
TM3 104 3.28x28 μ receptor 6DDE FFA1 receptor 5TZY
TM3 105 3.29x29 μ receptor 6DDE CCR9 5LWE
TM3 106 3.30x30 μ receptor 6DDE PAR2 5NDD
TM3 107 3.31x31 μ receptor 6DDE - -
TM3 108 3.32x32 μ receptor 6DDE AT2 receptor 5UNG
TM3 109 3.33x33 μ receptor 6DDE AT1 receptor 4ZUD
TM3 110 3.34x34 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 111 3.35x35 μ receptor 6DDE CCR2 5T1A
TM3 112 3.36x36 μ receptor 6DDE μ receptor 6DDE
TM3 113 3.37x37 μ receptor 6DDE μ receptor 6DDE
TM3 114 3.38x38 μ receptor 6DDE μ receptor 6DDE
TM3 115 3.39x39 μ receptor 6DDE μ receptor 6DDE
TM3 116 3.40x40 μ receptor 6DDE PAF receptor 5ZKQ
TM3 117 3.41x41 μ receptor 6DDE μ receptor 6DDE
TM3 118 3.42x42 μ receptor 6DDE PAR2 5NDD
TM3 119 3.43x43 μ receptor 6DDE μ receptor 6DDE
TM3 120 3.44x44 μ receptor 6DDE OX2 receptor 5WS3
TM3 121 3.45x45 μ receptor 6DDE 5-HT2B receptor 4IB4
TM3 122 3.46x46 μ receptor 6DDE P2Y1 receptor 4XNW
TM3 123 3.47x47 μ receptor 6DDE - -
TM3 124 3.48x48 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM3 125 3.49x49 μ receptor 6DDE μ receptor 6DDE
TM3 126 3.50x50 μ receptor 6DDE μ receptor 6DDE
TM3 127 3.51x51 μ receptor 6DDE μ receptor 6DDE
TM3 128 3.52x52 μ receptor 6DDE NTS1 receptor 4XES
TM3 129 3.53x53 μ receptor 6DDE C5a1 receptor 5O9H
TM3 130 3.54x54 μ receptor 6DDE P2Y12 receptor 4NTJ
TM3 131 3.55x55 μ receptor 6DDE - -
TM3 132 3.56x56 μ receptor 6DDE μ receptor 6DDE
ICL2 133 34.50x50 - - - -
ICL2 134 34.51x51 C5a1 receptor 5O9H μ receptor 6DDE
ICL2 135 34.52x52 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 136 34.53x53 C5a1 receptor 5O9H P2Y1 receptor 4XNW
ICL2 137 34.54x54 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 138 34.55x55 C5a1 receptor 5O9H - -
ICL2 139 34.56x56 C5a1 receptor 5O9H - -
ICL2 140 34.57x57 - - - -
TM4 141 4.38x38 μ receptor 6DDE μ receptor 6DDE
TM4 142 4.39x39 μ receptor 6DDE μ receptor 6DDE
TM4 143 4.40x40 μ receptor 6DDE μ receptor 6DDE
TM4 144 4.41x41 μ receptor 6DDE ETB receptor 5X93
TM4 145 4.42x42 μ receptor 6DDE μ receptor 6DDE
TM4 146 4.43x43 μ receptor 6DDE PAR1 3VW7
TM4 147 4.44x44 μ receptor 6DDE PAF receptor 5ZKQ
TM4 148 4.45x45 μ receptor 6DDE PAR2 5NDD
TM4 149 4.46x46 μ receptor 6DDE AT2 receptor 5UNG
TM4 150 4.47x47 μ receptor 6DDE PAR2 5NDD
TM4 151 4.48x48 μ receptor 6DDE CXCR4 3ODU
TM4 152 4.49x49 μ receptor 6DDE P2Y1 receptor 4XNW
TM4 153 4.50x50 μ receptor 6DDE μ receptor 6DDE
TM4 154 4.51x51 μ receptor 6DDE μ receptor 6DDE
TM4 155 4.52x52 μ receptor 6DDE - -
TM4 156 4.53x53 μ receptor 6DDE PAR1 3VW7
TM4 157 4.54x54 μ receptor 6DDE NTS1 receptor 4XES
TM4 158 4.55x55 μ receptor 6DDE μ receptor 6DDE
TM4 159 4.56x56 μ receptor 6DDE NTS1 receptor 4XES
TM4 160 4.57x57 AT1 receptor 4ZUD 5-HT1B receptor 4IAQ
TM4 161 4.58x59 AT1 receptor 4ZUD PAR2 5NDD
TM4 162 4.59x60 μ receptor 6DDE PAR2 5NDD
TM4 163 4.60x61 μ receptor 6DDE - -
TM4 164 4.61x62 μ receptor 6DDE NTS1 receptor 4XES
TM4 165 4.62x63 AT1 receptor 4ZUD AT1 receptor 4ZUD
TM4 166 4.63x64 AT1 receptor 4ZUD CXCR4 3ODU
TM4 167 4.64x65 AT1 receptor 4ZUD AT1 receptor 4ZUD
ECL2 168 μ receptor 6DDE - -
ECL2 169 μ receptor 6DDE μ receptor 6DDE
ECL2 170 μ receptor 6DDE - -
ECL2 171 μ receptor 6DDE - -
ECL2 172 μ receptor 6DDE - -
ECL2 173 μ receptor 6DDE - -
ECL2 174 μ receptor 6DDE - -
ECL2 175 μ receptor 6DDE - -
ECL2 176 μ receptor 6DDE - -
ECL2 177 μ receptor 6DDE - -
ECL2 178 - - - -
ECL2 179 45.50x50 μ receptor 6DDE μ receptor 6DDE
ECL2 180 45.51x51 μ receptor 6DDE - -
ECL2 181 45.52x52 μ receptor 6DDE - -
ECL2 182 - - - -
ECL2 183 - - - -
ECL2 184 - - - -
ECL2 185 - - - -
ECL2 186 - - - -
ECL2 187 - - - -
ECL2 188 - - - -
ECL2 189 - - - -
ECL2 190 - - - -
ECL2 191 - - - -
ECL2 192 - - - -
ECL2 193 - - - -
ECL2 194 - - - -
ECL2 195 - - - -
ECL2 196 - - - -
ECL2 197 - - - -
ECL2 198 - - - -
ECL2 199 - - - -
ECL2 200 - - - -
TM5 201 5.34x35 μ receptor 6DDE - -
TM5 202 5.35x36 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 203 5.36x37 μ receptor 6DDE CXCR4 3ODU
TM5 204 5.37x38 μ receptor 6DDE C5a1 receptor 5O9H
TM5 205 5.38x39 μ receptor 6DDE - -
TM5 206 5.39x40 μ receptor 6DDE PAR2 5NDD
TM5 207 5.40x41 μ receptor 6DDE μ receptor 6DDE
TM5 208 5.41x42 μ receptor 6DDE PAR2 5NDD
TM5 209 5.42x43 μ receptor 6DDE C5a1 receptor 5O9H
TM5 210 5.43x44 μ receptor 6DDE μ receptor 6DDE
TM5 211 5.44x45 μ receptor 6DDE 5-HT2B receptor 4IB4
TM5 212 5.45x46 μ receptor 6DDE FFA1 receptor 5TZY
TM5 213 5.46x461 μ receptor 6DDE AT1 receptor 4ZUD
TM5 214 5.47x47 μ receptor 6DDE μ receptor 6DDE
TM5 215 5.48x48 μ receptor 6DDE PAR2 5NDD
TM5 216 5.49x49 μ receptor 6DDE PAF receptor 5ZKQ
TM5 217 5.50x50 μ receptor 6DDE μ receptor 6DDE
TM5 218 5.51x51 μ receptor 6DDE P2Y12 receptor 4NTJ
TM5 219 5.52x52 μ receptor 6DDE PAR2 5NDD
TM5 220 5.53x53 μ receptor 6DDE μ receptor 6DDE
TM5 221 5.54x54 μ receptor 6DDE μ receptor 6DDE
TM5 222 5.55x55 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM5 223 5.56x56 μ receptor 6DDE PAF receptor 5ZKQ
TM5 224 5.57x57 μ receptor 6DDE μ receptor 6DDE
TM5 225 5.58x58 μ receptor 6DDE μ receptor 6DDE
TM5 226 5.59x59 μ receptor 6DDE - -
TM5 227 5.60x60 μ receptor 6DDE 5-HT1B receptor 5V54
TM5 228 5.61x61 μ receptor 6DDE β2-adrenoceptor 3SN6
TM5 229 5.62x62 μ receptor 6DDE NTS1 receptor 4XES
TM5 230 5.63x63 μ receptor 6DDE CXCR4 3ODU
TM5 231 5.64x64 μ receptor 6DDE NTS1 receptor 4XES
TM5 232 5.65x65 μ receptor 6DDE Rhodopsin 5DYS
TM5 233 5.66x66 μ receptor 6DDE μ receptor 6DDE
TM5 234 5.67x67 μ receptor 6DDE Rhodopsin 5DYS
TM5 235 5.68x68 μ receptor 6DDE C5a1 receptor 6C1R
ICL3 236 - - - -
ICL3 237 - - - -
ICL3 238 - - - -
ICL3 239 - - - -
TM6 240 6.30x30 μ receptor 6DDE C5a1 receptor 6C1R
TM6 241 6.31x31 μ receptor 6DDE - -
TM6 242 6.32x32 μ receptor 6DDE PAR2 5NDD
TM6 243 6.33x33 μ receptor 6DDE - -
TM6 244 6.34x34 μ receptor 6DDE AT1 receptor 4ZUD
TM6 245 6.35x35 μ receptor 6DDE 5-HT1B receptor 5V54
TM6 246 6.36x36 μ receptor 6DDE NTS1 receptor 4XES
TM6 247 6.37x37 μ receptor 6DDE PAF receptor 5ZKQ
TM6 248 6.38x38 μ receptor 6DDE AT1 receptor 4ZUD
TM6 249 6.39x39 μ receptor 6DDE CCR2 5T1A
TM6 250 6.40x40 μ receptor 6DDE PAR1 3VW7
TM6 251 6.41x41 μ receptor 6DDE P2Y12 receptor 4NTJ
TM6 252 6.42x42 μ receptor 6DDE NTS1 receptor 4XES
TM6 253 6.43x43 μ receptor 6DDE C5a1 receptor 5O9H
TM6 254 6.44x44 μ receptor 6DDE μ receptor 6DDE
TM6 255 6.45x45 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 256 6.46x46 μ receptor 6DDE 5-HT1B receptor 4IAQ
TM6 257 6.47x47 μ receptor 6DDE PAR2 5NDD
TM6 258 6.48x48 μ receptor 6DDE μ receptor 6DDE
TM6 259 6.49x49 μ receptor 6DDE apelin receptor 5VBL
TM6 260 6.50x50 μ receptor 6DDE μ receptor 6DDE
TM6 261 6.51x51 μ receptor 6DDE NTS1 receptor 4XES
TM6 262 6.52x52 μ receptor 6DDE μ receptor 6DDE
TM6 263 6.53x53 μ receptor 6DDE μ receptor 6DDE
TM6 264 6.54x54 μ receptor 6DDE - -
TM6 265 6.55x55 μ receptor 6DDE PAF receptor 5ZKQ
TM6 266 6.56x56 μ receptor 6DDE - -
TM6 267 6.57x57 μ receptor 6DDE AT1 receptor 4ZUD
TM6 268 6.58x58 μ receptor 6DDE 5-HT2B receptor 4IB4
TM6 269 6.59x59 μ receptor 6DDE P2Y1 receptor 4XNW
TM6 270 6.60x60 μ receptor 6DDE Rhodopsin 5DYS
TM6 271 6.61x61 μ receptor 6DDE - -
ECL3 272 - - - -
ECL3 273 Rhodopsin 5DYS - -
ECL3 274 Rhodopsin 5DYS Rhodopsin 5DYS
ECL3 275 Rhodopsin 5DYS - -
ECL3 276 - - - -
TM7 277 7.31x30 μ receptor 6DDE P2Y12 receptor 4NTJ
TM7 278 7.32x31 μ receptor 6DDE H1 receptor 3RZE
TM7 279 7.33x32 μ receptor 6DDE AT2 receptor 5UNG
TM7 280 7.34x33 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 281 7.35x34 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 282 7.36x35 μ receptor 6DDE PAR2 5NDD
TM7 283 7.37x36 μ receptor 6DDE NTS1 receptor 4XES
TM7 284 7.38x37 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 285 7.39x38 μ receptor 6DDE 5-HT2B receptor 4IB4
TM7 286 7.40x39 μ receptor 6DDE AT2 receptor 5UNG
TM7 287 7.41x40 μ receptor 6DDE FFA1 receptor 5TZY
TM7 288 7.42x41 μ receptor 6DDE P2Y12 receptor 4NTJ
TM7 289 7.43x42 μ receptor 6DDE P2Y1 receptor 4XNW
TM7 290 7.44x43 μ receptor 6DDE AT1 receptor 4ZUD
TM7 291 7.45x45 μ receptor 6DDE μ receptor 6DDE
TM7 292 7.46x46 μ receptor 6DDE Y1 receptor 5ZBH
TM7 293 7.47x47 μ receptor 6DDE Rhodopsin 4ZWJ
TM7 294 7.48x48 μ receptor 6DDE β2-adrenoceptor 3SN6
TM7 295 7.49x49 μ receptor 6DDE - -
TM7 296 7.50x50 μ receptor 6DDE μ receptor 6DDE
TM7 297 7.51x51 μ receptor 6DDE - -
TM7 298 7.52x52 μ receptor 6DDE μ receptor 6DDE
TM7 299 7.53x53 μ receptor 6DDE μ receptor 6DDE
TM7 300 7.54x54 μ receptor 6DDE - -
TM7 301 7.55x55 C5a1 receptor 5O9H PAR2 5NDD
TM7 302 7.56x56 C5a1 receptor 5O9H PAR2 5NDD
H8 303 8.47x47 μ receptor 4DKL CCR2 5T1A
H8 304 8.48x48 μ receptor 4DKL μ receptor 4DKL
H8 305 8.49x49 μ receptor 4DKL μ receptor 4DKL
H8 306 8.50x50 μ receptor 4DKL μ receptor 4DKL
H8 307 8.51x51 μ receptor 4DKL μ receptor 4DKL
H8 308 8.52x52 μ receptor 4DKL H1 receptor 3RZE
H8 309 8.53x53 μ receptor 4DKL NTS1 receptor 4BUO
H8 310 8.54x54 μ receptor 4DKL μ receptor 4DKL
H8 311 8.55x55 μ receptor 4DKL PAR2 5NDD
H8 312 8.56x56 μ receptor 4DKL 5-HT1B receptor 4IAQ
H8 313 8.57x57 μ receptor 4DKL - -
H8 314 8.58x58 μ receptor 4DKL 5-HT1B receptor 4IAQ
H8 315 8.59x59 μ receptor 4DKL apelin receptor 5VBL
H8 316 8.60x60 apelin receptor 5VBL - -
H8 317 8.61x61 apelin receptor 5VBL CCR9 5LWE
C-term 318 - - - -
C-term 319 - - - -
C-term 320 - - - -
C-term 321 - - - -
C-term 322 - - - -