GPR35 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 9.9 docs)

VERSION

2018-07-10

MAIN TEMPLATE

LPA6 receptor (sequence similarity: 47%) PDB: 5XSZ

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 77.7 10.5 11.8
Side-chains 26.1 51.6 22.3

Number of backbone templates: 6
Number of rotamer templates: 40

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5T1A
5XSZ
4DJH
6B73
5WIV
5X33
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 10 - - - -
N-term 11 - - - -
N-term 12 - - - -
N-term 13 - - - -
N-term 14 - - - -
TM1 15 1.27x27 CCR2 5T1A - -
TM1 16 1.28x28 CCR2 5T1A A2A receptor 5IU4
TM1 17 1.29x29 CCR2 5T1A Rhodopsin 5DYS
TM1 18 1.30x30 CCR2 5T1A κ receptor 6B73
TM1 19 1.31x31 LPA6 receptor 5XSZ κ receptor 6B73
TM1 20 1.32x32 LPA6 receptor 5XSZ US28 4XT1
TM1 21 1.33x33 LPA6 receptor 5XSZ CB1 receptor 5XRA
TM1 22 1.34x34 LPA6 receptor 5XSZ β2-adrenoceptor 3SN6
TM1 23 1.35x35 LPA6 receptor 5XSZ PAF receptor 5ZKP
TM1 24 1.36x36 LPA6 receptor 5XSZ - -
TM1 25 1.37x37 LPA6 receptor 5XSZ κ receptor 6B73
TM1 26 1.38x38 LPA6 receptor 5XSZ Rhodopsin 5DYS
TM1 27 1.39x39 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM1 28 1.40x40 LPA6 receptor 5XSZ US28 4XT1
TM1 29 1.41x41 LPA6 receptor 5XSZ κ receptor 6B73
TM1 30 1.42x42 LPA6 receptor 5XSZ Rhodopsin 5DYS
TM1 31 1.43x43 LPA6 receptor 5XSZ - -
TM1 32 1.44x44 LPA6 receptor 5XSZ κ receptor 6B73
TM1 33 1.45x45 LPA6 receptor 5XSZ PAF receptor 5ZKP
TM1 34 1.46x46 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM1 35 1.47x47 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM1 36 1.48x48 LPA6 receptor 5XSZ AT2 receptor 5UNG
TM1 37 1.49x49 LPA6 receptor 5XSZ PAR1 3VW7
TM1 38 1.50x50 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM1 39 1.51x51 LPA6 receptor 5XSZ κ receptor 6B73
TM1 40 1.52x52 LPA6 receptor 5XSZ κ receptor 6B73
TM1 41 1.53x53 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM1 42 1.54x54 LPA6 receptor 5XSZ PAF receptor 5ZKP
TM1 43 1.55x55 LPA6 receptor 5XSZ PAF receptor 5ZKP
TM1 44 1.56x56 LPA6 receptor 5XSZ κ receptor 6B73
TM1 45 1.57x57 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM1 46 1.58x58 LPA6 receptor 5XSZ AT2 receptor 5UNG
TM1 47 1.59x59 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM1 48 1.60x60 LPA6 receptor 5XSZ - -
ICL1 49 12.48x48 - - - -
ICL1 50 12.49x49 κ receptor 4DJH M3 receptor 4U15
ICL1 51 12.50x50 κ receptor 4DJH - -
ICL1 52 12.51x51 - - - -
TM2 53 2.37x37 LPA6 receptor 5XSZ κ receptor 6B73
TM2 54 2.38x38 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 55 2.39x39 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 56 2.40x40 LPA6 receptor 5XSZ - -
TM2 57 2.41x41 LPA6 receptor 5XSZ κ receptor 6B73
TM2 58 2.42x42 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 59 2.43x43 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 60 2.44x44 LPA6 receptor 5XSZ β2-adrenoceptor 3SN6
TM2 61 2.45x45 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 62 2.46x46 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 63 2.47x47 LPA6 receptor 5XSZ κ receptor 6B73
TM2 64 2.48x48 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 65 2.49x49 LPA6 receptor 5XSZ κ receptor 6B73
TM2 66 2.50x50 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 67 2.51x51 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 68 2.52x52 LPA6 receptor 5XSZ AT1 receptor 4ZUD
TM2 69 2.53x53 LPA6 receptor 5XSZ AT2 receptor 5UNG
TM2 70 2.54x54 LPA6 receptor 5XSZ AT2 receptor 5UNG
TM2 71 2.55x55 LPA6 receptor 5XSZ US28 4XT1
TM2 72 2.56x56 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 73 2.57x57 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 74 2.58x58 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM2 75 2.59x59 LPA6 receptor 5XSZ κ receptor 6B73
TM2 76 2.60x60 LPA6 receptor 5XSZ D2 receptor 6CM4
TM2 77 2.61x61 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM2 78 2.62x62 LPA6 receptor 5XSZ CCR2 5T1A
TM2 79 2.63x63 LPA6 receptor 5XSZ CCR2 5T1A
TM2 80 2.64x64 LPA6 receptor 5XSZ US28 4XT1
TM2 81 2.65x65 LPA6 receptor 5XSZ - -
TM2 82 2.66x66 LPA6 receptor 5XSZ US28 4XT1
ECL1 83 - - - -
ECL1 84 - - - -
ECL1 85 - - - -
ECL1 86 - - - -
ECL1 87 - - - -
TM3 88 3.24x24 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 89 3.25x25 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 90 3.26x26 LPA6 receptor 5XSZ CCR5 5UIW
TM3 91 3.27x27 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 92 3.28x28 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 93 3.29x29 LPA6 receptor 5XSZ LPA1 receptor 4Z35
TM3 94 3.30x30 LPA6 receptor 5XSZ CB1 receptor 5XRA
TM3 95 3.31x31 LPA6 receptor 5XSZ κ receptor 6B73
TM3 96 3.32x32 LPA6 receptor 5XSZ CCR2 5T1A
TM3 97 3.33x33 LPA6 receptor 5XSZ A2A receptor 5G53
TM3 98 3.34x34 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 99 3.35x35 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 100 3.36x36 LPA6 receptor 5XSZ - -
TM3 101 3.37x37 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 102 3.38x38 LPA6 receptor 5XSZ - -
TM3 103 3.39x39 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 104 3.40x40 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 105 3.41x41 LPA6 receptor 5XSZ P2Y12 receptor 4NTJ
TM3 106 3.42x42 LPA6 receptor 5XSZ PAR1 3VW7
TM3 107 3.43x43 LPA6 receptor 5XSZ NTS1 receptor 5T04
TM3 108 3.44x44 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 109 3.45x45 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM3 110 3.46x46 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 111 3.47x47 LPA6 receptor 5XSZ US28 4XT1
TM3 112 3.48x48 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 113 3.49x49 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 114 3.50x50 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 115 3.51x51 LPA6 receptor 5XSZ κ receptor 6B73
TM3 116 3.52x52 LPA6 receptor 5XSZ 5-HT2C receptor 6BQG
TM3 117 3.53x53 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM3 118 3.54x54 LPA6 receptor 5XSZ κ receptor 6B73
TM3 119 3.55x55 LPA6 receptor 5XSZ 5-HT2C receptor 6BQG
TM3 120 3.56x56 LPA6 receptor 5XSZ κ receptor 6B73
ICL2 121 34.50x50 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 122 34.51x51 LPA6 receptor 5XSZ A2A receptor 5G53
ICL2 123 34.52x52 LPA6 receptor 5XSZ A2A receptor 5G53
ICL2 124 34.53x53 LPA6 receptor 5XSZ κ receptor 6B73
ICL2 125 34.54x54 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 126 34.55x55 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 127 34.56x56 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 128 34.57x57 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM4 129 4.38x38 LPA6 receptor 5XSZ NTS1 receptor 5T04
TM4 130 4.39x39 LPA6 receptor 5XSZ κ receptor 6B73
TM4 131 4.40x40 LPA6 receptor 5XSZ μ receptor 5C1M
TM4 132 4.41x41 LPA6 receptor 5XSZ US28 4XT1
TM4 133 4.42x42 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM4 134 4.43x43 LPA6 receptor 5XSZ A1 receptor 6D9H
TM4 135 4.44x44 LPA6 receptor 5XSZ NOP receptor 5DHG
TM4 136 4.45x45 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM4 137 4.46x46 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM4 138 4.47x47 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM4 139 4.48x48 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM4 140 4.49x49 LPA6 receptor 5XSZ apelin receptor 5VBL
TM4 141 4.50x50 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM4 142 4.51x51 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM4 143 4.52x52 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM4 144 4.53x53 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM4 145 4.54x54 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM4 146 4.55x55 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM4 147 4.56x56 LPA6 receptor 5XSZ AT2 receptor 5UNG
TM4 148 4.57x57 LPA6 receptor 5XSZ FFA1 receptor 5TZY
TM4 149 4.58x58 LPA6 receptor 5XSZ CB1 receptor 5XRA
TM4 150 4.59x59 LPA6 receptor 5XSZ D4 receptor 5WIV
TM4 151 4.60x60 LPA6 receptor 5XSZ - -
TM4 152 4.61x61 LPA6 receptor 5XSZ - -
TM4 153 4.62x62 LPA6 receptor 5XSZ NTS1 receptor 5T04
TM4 154 4.63x63 LPA6 receptor 5XSZ κ receptor 6B73
TM4 155 4.64x64 LPA6 receptor 5XSZ ETB receptor 5X93
ECL2 156 - - - -
ECL2 157 D4 receptor 5WIV - -
ECL2 158 D4 receptor 5WIV - -
ECL2 159 - - - -
ECL2 160 - - - -
ECL2 161 - - - -
ECL2 162 45.50x50 κ receptor 4DJH κ receptor 4DJH
ECL2 163 45.51x51 κ receptor 4DJH Y1 receptor 5ZBH
ECL2 164 45.52x52 κ receptor 4DJH CXCR4 3ODU
ECL2 165 - - - -
ECL2 166 BLT1 receptor 5X33 - -
ECL2 167 - - - -
TM5 168 5.35x36 LPA6 receptor 5XSZ P2Y12 receptor 4NTJ
TM5 169 5.36x37 LPA6 receptor 5XSZ μ receptor 5C1M
TM5 170 5.37x38 LPA6 receptor 5XSZ κ receptor 6B73
TM5 171 5.38x39 LPA6 receptor 5XSZ - -
TM5 172 5.39x40 LPA6 receptor 5XSZ PAR1 3VW7
TM5 173 5.40x41 LPA6 receptor 5XSZ CB1 receptor 5XRA
TM5 174 5.41x42 LPA6 receptor 5XSZ β2-adrenoceptor 3SN6
TM5 175 5.42x43 LPA6 receptor 5XSZ OX2 receptor 5WS3
TM5 176 5.43x44 LPA6 receptor 5XSZ - -
TM5 177 5.44x45 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM5 178 5.45x46 LPA6 receptor 5XSZ AT2 receptor 5UNG
TM5 179 5.46x461 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM5 180 5.47x47 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM5 181 5.48x48 LPA6 receptor 5XSZ β2-adrenoceptor 3SN6
TM5 182 5.49x49 LPA6 receptor 5XSZ PAF receptor 5ZKP
TM5 183 5.50x50 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM5 184 5.51x51 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM5 185 5.52x52 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM5 186 5.53x53 LPA6 receptor 5XSZ US28 4XT1
TM5 187 5.54x54 LPA6 receptor 5XSZ BLT1 receptor 5X33
TM5 188 5.55x55 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM5 189 5.56x56 LPA6 receptor 5XSZ PAF receptor 5ZKP
TM5 190 5.57x57 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM5 191 5.58x58 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM5 192 5.59x59 LPA6 receptor 5XSZ PAF receptor 5ZKP
TM5 193 5.60x60 LPA6 receptor 5XSZ Y1 receptor 5ZBH
TM5 194 5.61x61 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM5 195 5.62x62 LPA6 receptor 5XSZ Rhodopsin 5DYS
TM5 196 5.63x63 LPA6 receptor 5XSZ - -
TM5 197 5.64x64 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM5 198 5.65x65 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM5 199 5.66x66 LPA6 receptor 5XSZ US28 4XT1
TM5 200 5.67x67 LPA6 receptor 5XSZ - -
TM5 201 5.68x68 κ receptor 4DJH 5-HT1B receptor 6G79
ICL3 202 - - - -
ICL3 203 - - - -
ICL3 204 - - - -
ICL3 205 - - - -
TM6 206 6.24x24 κ receptor 6B73 5-HT2B receptor 5TVN
TM6 207 6.25x25 κ receptor 6B73 NTS1 receptor 5T04
TM6 208 6.26x26 κ receptor 6B73 OX2 receptor 5WS3
TM6 209 6.27x27 κ receptor 6B73 5-HT1B receptor 6G79
TM6 210 6.28x28 κ receptor 6B73 PAR2 5NDD
TM6 211 6.29x29 LPA6 receptor 5XSZ - -
TM6 212 6.30x30 LPA6 receptor 5XSZ Y1 receptor 5ZBH
TM6 213 6.31x31 LPA6 receptor 5XSZ μ receptor 5C1M
TM6 214 6.32x32 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM6 215 6.33x33 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM6 216 6.34x34 LPA6 receptor 5XSZ A2A receptor 5G53
TM6 217 6.35x35 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM6 218 6.36x36 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM6 219 6.37x37 LPA6 receptor 5XSZ κ receptor 6B73
TM6 220 6.38x38 LPA6 receptor 5XSZ - -
TM6 221 6.39x39 LPA6 receptor 5XSZ US28 4XT1
TM6 222 6.40x40 LPA6 receptor 5XSZ - -
TM6 223 6.41x41 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM6 224 6.42x42 LPA6 receptor 5XSZ US28 4XT1
TM6 225 6.43x43 LPA6 receptor 5XSZ κ receptor 6B73
TM6 226 6.44x44 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM6 227 6.45x45 LPA6 receptor 5XSZ κ receptor 6B73
TM6 228 6.46x46 LPA6 receptor 5XSZ κ receptor 6B73
TM6 229 6.47x47 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM6 230 6.48x48 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM6 231 6.49x49 LPA6 receptor 5XSZ US28 4XT1
TM6 232 6.50x50 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM6 233 6.51x51 LPA6 receptor 5XSZ A2A receptor 5G53
TM6 234 6.52x52 LPA6 receptor 5XSZ κ receptor 6B73
TM6 235 6.53x53 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM6 236 6.54x54 LPA6 receptor 5XSZ CXCR4 3ODU
TM6 237 6.55x55 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM6 238 6.56x56 LPA6 receptor 5XSZ P2Y1 receptor 4XNW
TM6 239 6.57x57 LPA6 receptor 5XSZ κ receptor 6B73
TM6 240 6.58x58 LPA6 receptor 5XSZ - -
TM6 241 6.59x59 LPA6 receptor 5XSZ A1 receptor 6D9H
TM6 242 6.60x60 LPA6 receptor 5XSZ - -
TM6 243 6.61x61 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ECL3 244 - - - -
ECL3 245 - - - -
ECL3 246 - - - -
ECL3 247 - - - -
ECL3 248 - - - -
ECL3 249 - - - -
ECL3 250 - - - -
TM7 251 7.28x27 LPA6 receptor 5XSZ ETB receptor 5X93
TM7 252 7.29x28 LPA6 receptor 5XSZ PAR1 3VW7
TM7 253 7.30x29 LPA6 receptor 5XSZ NOP receptor 5DHG
TM7 254 7.31x30 LPA6 receptor 5XSZ AT2 receptor 5UNG
TM7 255 7.32x31 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM7 256 7.33x32 LPA6 receptor 5XSZ US28 4XT1
TM7 257 7.34x33 LPA6 receptor 5XSZ US28 4XT1
TM7 258 7.35x34 LPA6 receptor 5XSZ 5-HT2B receptor 5TUD
TM7 259 7.36x35 LPA6 receptor 5XSZ κ receptor 6B73
TM7 260 7.37x36 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM7 261 7.38x37 LPA6 receptor 5XSZ US28 4XT1
TM7 262 7.39x38 LPA6 receptor 5XSZ CB1 receptor 5XRA
TM7 263 7.40x39 LPA6 receptor 5XSZ - -
TM7 264 7.41x40 LPA6 receptor 5XSZ κ receptor 6B73
TM7 265 7.42x41 LPA6 receptor 5XSZ A2A receptor 5G53
TM7 266 7.43x42 LPA6 receptor 5XSZ - -
TM7 267 7.44x43 LPA6 receptor 5XSZ NTS1 receptor 5T04
TM7 268 7.45x45 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM7 269 7.46x46 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM7 270 7.47x47 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM7 271 7.48x48 LPA6 receptor 5XSZ κ receptor 6B73
TM7 272 7.49x49 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM7 273 7.50x50 LPA6 receptor 5XSZ - -
TM7 274 7.51x51 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM7 275 7.52x52 LPA6 receptor 5XSZ M2 receptor 4MQT
TM7 276 7.53x53 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM7 277 7.54x54 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM7 278 7.55x55 LPA6 receptor 5XSZ A2A receptor 5G53
TM7 279 7.56x56 LPA6 receptor 5XSZ Rhodopsin 5DYS
H8 280 8.47x47 κ receptor 4DJH - -
H8 281 8.48x48 κ receptor 4DJH 5-HT2C receptor 6BQG
H8 282 8.49x49 κ receptor 4DJH CCR5 5UIW
H8 283 8.50x50 κ receptor 4DJH κ receptor 4DJH
H8 284 8.51x51 κ receptor 4DJH AT2 receptor 5UNF
H8 285 8.52x52 κ receptor 4DJH OX2 receptor 5WS3
H8 286 8.53x53 κ receptor 4DJH 5-HT2B receptor 5TUD
H8 287 8.54x54 κ receptor 4DJH - -
H8 288 8.55x55 κ receptor 4DJH - -
H8 289 8.56x56 κ receptor 4DJH M1 receptor 5CXV
H8 290 8.57x57 κ receptor 4DJH OX2 receptor 5WS3
H8 291 8.58x58 κ receptor 4DJH - -
C-term 292 - - - -
C-term 293 - - - -
C-term 294 - - - -
C-term 295 - - - -
C-term 296 - - - -