GPR35 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): -1.18 docs)

VERSION

2018-07-10

MAIN TEMPLATE

κ receptor (sequence similarity: 45%) PDB: 4DJH

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 81.9 6.6 11.5
Side-chains 23.0 55.1 22.0

Number of backbone templates: 6
Number of rotamer templates: 40

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5T1A
4DJH
6B73
5XSZ
5WIV
5X33
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 10 - - - -
N-term 11 - - - -
N-term 12 - - - -
N-term 13 - - - -
N-term 14 - - - -
TM1 15 1.27x27 CCR2 5T1A - -
TM1 16 1.28x28 CCR2 5T1A A2A receptor 5IU4
TM1 17 1.29x29 CCR2 5T1A Rhodopsin 1GZM
TM1 18 1.30x30 κ receptor 4DJH κ receptor 4DJH
TM1 19 1.31x31 κ receptor 4DJH κ receptor 4DJH
TM1 20 1.32x32 κ receptor 4DJH NOP receptor 5DHG
TM1 21 1.33x33 κ receptor 4DJH BLT1 receptor 5X33
TM1 22 1.34x34 κ receptor 4DJH β2-adrenoceptor 5JQH
TM1 23 1.35x35 κ receptor 4DJH PAF receptor 5ZKP
TM1 24 1.36x36 κ receptor 4DJH - -
TM1 25 1.37x37 κ receptor 4DJH κ receptor 4DJH
TM1 26 1.38x38 κ receptor 4DJH Rhodopsin 1GZM
TM1 27 1.39x39 κ receptor 4DJH BLT1 receptor 5X33
TM1 28 1.40x40 κ receptor 4DJH Y1 receptor 5ZBH
TM1 29 1.41x41 κ receptor 4DJH κ receptor 4DJH
TM1 30 1.42x42 κ receptor 4DJH Rhodopsin 1GZM
TM1 31 1.43x43 κ receptor 4DJH - -
TM1 32 1.44x44 κ receptor 4DJH κ receptor 4DJH
TM1 33 1.45x45 κ receptor 4DJH ETB receptor 5X93
TM1 34 1.46x46 κ receptor 4DJH κ receptor 4DJH
TM1 35 1.47x47 κ receptor 4DJH κ receptor 4DJH
TM1 36 1.48x48 κ receptor 4DJH NOP receptor 5DHG
TM1 37 1.49x49 κ receptor 4DJH H1 receptor 3RZE
TM1 38 1.50x50 κ receptor 4DJH κ receptor 4DJH
TM1 39 1.51x51 κ receptor 4DJH κ receptor 4DJH
TM1 40 1.52x52 κ receptor 4DJH κ receptor 4DJH
TM1 41 1.53x53 κ receptor 4DJH LPA6 receptor 5XSZ
TM1 42 1.54x54 κ receptor 4DJH ETB receptor 5X93
TM1 43 1.55x55 κ receptor 4DJH BLT1 receptor 5X33
TM1 44 1.56x56 κ receptor 4DJH κ receptor 4DJH
TM1 45 1.57x57 κ receptor 4DJH M1 receptor 5CXV
TM1 46 1.58x58 κ receptor 4DJH AT2 receptor 5UNG
TM1 47 1.59x59 κ receptor 4DJH LPA6 receptor 5XSZ
TM1 48 1.60x60 κ receptor 4DJH - -
ICL1 49 12.48x48 κ receptor 4DJH AT1 receptor 4YAY
ICL1 50 12.49x49 κ receptor 4DJH M3 receptor 4U15
ICL1 51 12.50x50 κ receptor 4DJH - -
ICL1 52 12.51x51 κ receptor 4DJH - -
TM2 53 2.37x37 κ receptor 4DJH κ receptor 4DJH
TM2 54 2.38x38 κ receptor 4DJH LPA6 receptor 5XSZ
TM2 55 2.39x39 κ receptor 4DJH κ receptor 4DJH
TM2 56 2.40x40 κ receptor 4DJH - -
TM2 57 2.41x41 κ receptor 4DJH κ receptor 4DJH
TM2 58 2.42x42 κ receptor 4DJH κ receptor 4DJH
TM2 59 2.43x43 κ receptor 4DJH LPA1 receptor 4Z35
TM2 60 2.44x44 κ receptor 4DJH β2-adrenoceptor 5JQH
TM2 61 2.45x45 κ receptor 4DJH κ receptor 4DJH
TM2 62 2.46x46 κ receptor 4DJH κ receptor 4DJH
TM2 63 2.47x47 κ receptor 4DJH κ receptor 4DJH
TM2 64 2.48x48 κ receptor 4DJH CXCR4 3ODU
TM2 65 2.49x49 κ receptor 4DJH κ receptor 4DJH
TM2 66 2.50x50 κ receptor 4DJH κ receptor 4DJH
TM2 67 2.51x51 κ receptor 4DJH AT1 receptor 4ZUD
TM2 68 2.52x52 κ receptor 4DJH AT1 receptor 4ZUD
TM2 69 2.53x53 κ receptor 4DJH D4 receptor 5WIV
TM2 70 2.54x54 κ receptor 4DJH AT1 receptor 4ZUD
TM2 71 2.55x55 κ receptor 4DJH US28 4XT1
TM2 72 2.56x56 κ receptor 4DJH κ receptor 4DJH
TM2 73 2.57x57 κ receptor 4DJH AT1 receptor 4ZUD
TM2 74 2.58x58 κ receptor 4DJH κ receptor 4DJH
TM2 75 2.59x59 κ receptor 4DJH κ receptor 4DJH
TM2 76 2.60x60 κ receptor 4DJH D2 receptor 6CM4
TM2 77 2.61x61 κ receptor 4DJH OX2 receptor 5WS3
TM2 78 2.62x62 κ receptor 4DJH CCR2 5T1A
TM2 79 2.63x63 κ receptor 4DJH CCR2 5T1A
TM2 80 2.64x64 κ receptor 4DJH BLT1 receptor 5X33
TM2 81 2.65x65 κ receptor 4DJH - -
TM2 82 2.66x66 κ receptor 4DJH US28 4XT1
ECL1 83 - - - -
ECL1 84 - - - -
ECL1 85 - - - -
ECL1 86 - - - -
ECL1 87 - - - -
TM3 88 3.24x24 κ receptor 4DJH κ receptor 4DJH
TM3 89 3.25x25 κ receptor 4DJH κ receptor 4DJH
TM3 90 3.26x26 κ receptor 4DJH CCR5 5UIW
TM3 91 3.27x27 κ receptor 4DJH CCR2 5T1A
TM3 92 3.28x28 κ receptor 4DJH apelin receptor 5VBL
TM3 93 3.29x29 κ receptor 4DJH LPA1 receptor 4Z35
TM3 94 3.30x30 κ receptor 4DJH CCR2 5T1A
TM3 95 3.31x31 κ receptor 4DJH κ receptor 4DJH
TM3 96 3.32x32 κ receptor 4DJH CCR2 5T1A
TM3 97 3.33x33 κ receptor 4DJH C5a1 receptor 5O9H
TM3 98 3.34x34 κ receptor 4DJH LPA1 receptor 4Z35
TM3 99 3.35x35 κ receptor 4DJH κ receptor 4DJH
TM3 100 3.36x36 κ receptor 4DJH - -
TM3 101 3.37x37 κ receptor 4DJH AT1 receptor 4ZUD
TM3 102 3.38x38 κ receptor 4DJH - -
TM3 103 3.39x39 κ receptor 4DJH κ receptor 4DJH
TM3 104 3.40x40 κ receptor 4DJH κ receptor 4DJH
TM3 105 3.41x41 κ receptor 4DJH P2Y12 receptor 4NTJ
TM3 106 3.42x42 κ receptor 4DJH AT1 receptor 4ZUD
TM3 107 3.43x43 κ receptor 4DJH NTS1 receptor 4BUO
TM3 108 3.44x44 κ receptor 4DJH κ receptor 4DJH
TM3 109 3.45x45 κ receptor 4DJH NOP receptor 5DHG
TM3 110 3.46x46 κ receptor 4DJH CXCR4 3ODU
TM3 111 3.47x47 κ receptor 4DJH OX2 receptor 5WS3
TM3 112 3.48x48 κ receptor 4DJH κ receptor 4DJH
TM3 113 3.49x49 κ receptor 4DJH κ receptor 4DJH
TM3 114 3.50x50 κ receptor 4DJH κ receptor 4DJH
TM3 115 3.51x51 κ receptor 4DJH κ receptor 4DJH
TM3 116 3.52x52 κ receptor 4DJH NOP receptor 5DHG
TM3 117 3.53x53 κ receptor 4DJH κ receptor 4DJH
TM3 118 3.54x54 κ receptor 4DJH κ receptor 4DJH
TM3 119 3.55x55 κ receptor 4DJH A2A receptor 3VG9
TM3 120 3.56x56 κ receptor 4DJH κ receptor 4DJH
ICL2 121 34.50x50 - - - -
ICL2 122 34.51x51 LPA6 receptor 5XSZ OX1 receptor 4ZJ8
ICL2 123 34.52x52 LPA6 receptor 5XSZ CCR9 5LWE
ICL2 124 34.53x53 LPA6 receptor 5XSZ CCR2 5T1A
ICL2 125 34.54x54 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 126 34.55x55 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 127 34.56x56 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 128 34.57x57 - - - -
TM4 129 4.38x38 κ receptor 4DJH 5-HT2C receptor 6BQH
TM4 130 4.39x39 κ receptor 4DJH κ receptor 4DJH
TM4 131 4.40x40 κ receptor 4DJH μ receptor 4DKL
TM4 132 4.41x41 κ receptor 4DJH US28 4XT1
TM4 133 4.42x42 κ receptor 4DJH κ receptor 4DJH
TM4 134 4.43x43 κ receptor 4DJH ETB receptor 5X93
TM4 135 4.44x44 κ receptor 4DJH NOP receptor 5DHG
TM4 136 4.45x45 κ receptor 4DJH NOP receptor 5DHG
TM4 137 4.46x46 κ receptor 4DJH AT1 receptor 4ZUD
TM4 138 4.47x47 κ receptor 4DJH 5-HT2C receptor 6BQH
TM4 139 4.48x48 κ receptor 4DJH Y1 receptor 5ZBH
TM4 140 4.49x49 κ receptor 4DJH apelin receptor 5VBL
TM4 141 4.50x50 κ receptor 4DJH κ receptor 4DJH
TM4 142 4.51x51 κ receptor 4DJH δ receptor 4N6H
TM4 143 4.52x52 κ receptor 4DJH κ receptor 4DJH
TM4 144 4.53x53 κ receptor 4DJH LPA6 receptor 5XSZ
TM4 145 4.54x54 κ receptor 4DJH 5-HT2C receptor 6BQH
TM4 146 4.55x55 κ receptor 4DJH δ receptor 4N6H
TM4 147 4.56x56 κ receptor 4DJH Y1 receptor 5ZBH
TM4 148 4.57x57 κ receptor 4DJH FFA1 receptor 5TZY
TM4 149 4.58x58 κ receptor 4DJH NOP receptor 5DHG
TM4 150 4.59x59 κ receptor 4DJH D4 receptor 5WIV
TM4 151 4.60x60 κ receptor 4DJH - -
TM4 152 4.61x61 κ receptor 4DJH - -
TM4 153 4.62x62 κ receptor 4DJH BLT1 receptor 5X33
TM4 154 4.63x63 κ receptor 4DJH κ receptor 4DJH
TM4 155 4.64x64 κ receptor 4DJH κ receptor 4DJH
ECL2 156 - - - -
ECL2 157 D4 receptor 5WIV - -
ECL2 158 D4 receptor 5WIV - -
ECL2 159 - - - -
ECL2 160 - - - -
ECL2 161 - - - -
ECL2 162 45.50x50 κ receptor 4DJH κ receptor 4DJH
ECL2 163 45.51x51 κ receptor 4DJH Y1 receptor 5ZBH
ECL2 164 45.52x52 κ receptor 4DJH CXCR4 3ODU
ECL2 165 - - - -
ECL2 166 BLT1 receptor 5X33 - -
ECL2 167 - - - -
TM5 168 5.35x36 κ receptor 4DJH P2Y12 receptor 4NTJ
TM5 169 5.36x37 κ receptor 4DJH CCR2 5T1A
TM5 170 5.37x38 κ receptor 4DJH κ receptor 4DJH
TM5 171 5.38x39 κ receptor 4DJH - -
TM5 172 5.39x40 κ receptor 4DJH PAR1 3VW7
TM5 173 5.40x41 κ receptor 4DJH CB1 receptor 5TGZ
TM5 174 5.41x42 κ receptor 4DJH β2-adrenoceptor 5JQH
TM5 175 5.42x43 κ receptor 4DJH OX2 receptor 5WS3
TM5 176 5.43x44 κ receptor 4DJH - -
TM5 177 5.44x45 κ receptor 4DJH NOP receptor 5DHG
TM5 178 5.45x46 κ receptor 4DJH CCR2 5T1A
TM5 179 5.46x461 κ receptor 4DJH AT1 receptor 4ZUD
TM5 180 5.47x47 κ receptor 4DJH κ receptor 4DJH
TM5 181 5.48x48 κ receptor 4DJH D2 receptor 6CM4
TM5 182 5.49x49 κ receptor 4DJH CCR2 5T1A
TM5 183 5.50x50 κ receptor 4DJH κ receptor 4DJH
TM5 184 5.51x51 κ receptor 4DJH CCR2 5T1A
TM5 185 5.52x52 κ receptor 4DJH ETB receptor 5X93
TM5 186 5.53x53 κ receptor 4DJH NOP receptor 5DHG
TM5 187 5.54x54 κ receptor 4DJH BLT1 receptor 5X33
TM5 188 5.55x55 κ receptor 4DJH CCR2 5T1A
TM5 189 5.56x56 κ receptor 4DJH ETB receptor 5X93
TM5 190 5.57x57 κ receptor 4DJH κ receptor 4DJH
TM5 191 5.58x58 κ receptor 4DJH LPA6 receptor 5XSZ
TM5 192 5.59x59 κ receptor 4DJH OX2 receptor 5WS3
TM5 193 5.60x60 κ receptor 4DJH Y1 receptor 5ZBH
TM5 194 5.61x61 κ receptor 4DJH β2-adrenoceptor 5JQH
TM5 195 5.62x62 κ receptor 4DJH Rhodopsin 1GZM
TM5 196 5.63x63 κ receptor 4DJH - -
TM5 197 5.64x64 κ receptor 4DJH AT1 receptor 4ZUD
TM5 198 5.65x65 κ receptor 4DJH κ receptor 4DJH
TM5 199 5.66x66 κ receptor 4DJH apelin receptor 5VBL
TM5 200 5.67x67 κ receptor 4DJH - -
TM5 201 5.68x68 κ receptor 4DJH BLT1 receptor 5X33
ICL3 202 - - - -
ICL3 203 - - - -
ICL3 204 - - - -
ICL3 205 - - - -
TM6 206 6.24x24 κ receptor 6B73 5-HT2B receptor 5TVN
TM6 207 6.25x25 κ receptor 6B73 NTS1 receptor 4BUO
TM6 208 6.26x26 κ receptor 6B73 OX2 receptor 5WS3
TM6 209 6.27x27 κ receptor 6B73 CB1 receptor 5TGZ
TM6 210 6.28x28 κ receptor 4DJH PAR2 5NDD
TM6 211 6.29x29 κ receptor 4DJH OX2 receptor 5WS3
TM6 212 6.30x30 κ receptor 4DJH Y1 receptor 5ZBH
TM6 213 6.31x31 κ receptor 4DJH NOP receptor 5DHG
TM6 214 6.32x32 κ receptor 4DJH CXCR4 3ODU
TM6 215 6.33x33 κ receptor 4DJH CCR2 5T1A
TM6 216 6.34x34 κ receptor 4DJH OX2 receptor 5WS3
TM6 217 6.35x35 κ receptor 4DJH κ receptor 4DJH
TM6 218 6.36x36 κ receptor 4DJH δ receptor 4N6H
TM6 219 6.37x37 κ receptor 4DJH κ receptor 4DJH
TM6 220 6.38x38 κ receptor 4DJH - -
TM6 221 6.39x39 κ receptor 4DJH AT1 receptor 4ZUD
TM6 222 6.40x40 κ receptor 4DJH - -
TM6 223 6.41x41 κ receptor 4DJH OX2 receptor 5WS3
TM6 224 6.42x42 κ receptor 4DJH AT1 receptor 4ZUD
TM6 225 6.43x43 κ receptor 4DJH κ receptor 4DJH
TM6 226 6.44x44 κ receptor 4DJH κ receptor 4DJH
TM6 227 6.45x45 κ receptor 4DJH κ receptor 4DJH
TM6 228 6.46x46 κ receptor 4DJH κ receptor 4DJH
TM6 229 6.47x47 κ receptor 4DJH κ receptor 4DJH
TM6 230 6.48x48 κ receptor 4DJH LPA6 receptor 5XSZ
TM6 231 6.49x49 κ receptor 4DJH CXCR4 3ODU
TM6 232 6.50x50 κ receptor 4DJH κ receptor 4DJH
TM6 233 6.51x51 κ receptor 4DJH ETB receptor 5X93
TM6 234 6.52x52 κ receptor 4DJH κ receptor 4DJH
TM6 235 6.53x53 κ receptor 4DJH NOP receptor 5DHG
TM6 236 6.54x54 κ receptor 4DJH CXCR4 3ODU
TM6 237 6.55x55 κ receptor 4DJH CCR5 5UIW
TM6 238 6.56x56 κ receptor 4DJH Y1 receptor 5ZBH
TM6 239 6.57x57 κ receptor 4DJH δ receptor 4N6H
TM6 240 6.58x58 κ receptor 4DJH - -
TM6 241 6.59x59 κ receptor 4DJH ETB receptor 5X93
TM6 242 6.60x60 κ receptor 4DJH - -
TM6 243 6.61x61 κ receptor 4DJH δ receptor 4N6H
ECL3 244 - - - -
ECL3 245 - - - -
ECL3 246 - - - -
ECL3 247 - - - -
ECL3 248 - - - -
ECL3 249 - - - -
ECL3 250 - - - -
TM7 251 7.28x27 LPA6 receptor 5XSZ ETB receptor 5X93
TM7 252 7.29x28 LPA6 receptor 5XSZ NOP receptor 5DHG
TM7 253 7.30x29 LPA6 receptor 5XSZ NOP receptor 5DHG
TM7 254 7.31x30 κ receptor 4DJH CCR9 5LWE
TM7 255 7.32x31 κ receptor 4DJH BLT1 receptor 5X33
TM7 256 7.33x32 κ receptor 4DJH D4 receptor 5WIU
TM7 257 7.34x33 κ receptor 4DJH AT1 receptor 4ZUD
TM7 258 7.35x34 κ receptor 4DJH NOP receptor 5DHG
TM7 259 7.36x35 κ receptor 4DJH κ receptor 4DJH
TM7 260 7.37x36 κ receptor 4DJH AT1 receptor 4ZUD
TM7 261 7.38x37 κ receptor 4DJH AT1 receptor 4ZUD
TM7 262 7.39x38 κ receptor 4DJH CB1 receptor 5TGZ
TM7 263 7.40x39 κ receptor 4DJH - -
TM7 264 7.41x40 κ receptor 4DJH κ receptor 4DJH
TM7 265 7.42x41 κ receptor 4DJH apelin receptor 5VBL
TM7 266 7.43x42 κ receptor 4DJH - -
TM7 267 7.44x43 κ receptor 4DJH δ receptor 4N6H
TM7 268 7.45x45 κ receptor 4DJH κ receptor 4DJH
TM7 269 7.46x46 κ receptor 4DJH CCR2 5T1A
TM7 270 7.47x47 κ receptor 4DJH AT1 receptor 4ZUD
TM7 271 7.48x48 κ receptor 4DJH κ receptor 4DJH
TM7 272 7.49x49 κ receptor 4DJH LPA6 receptor 5XSZ
TM7 273 7.50x50 κ receptor 4DJH - -
TM7 274 7.51x51 κ receptor 4DJH κ receptor 4DJH
TM7 275 7.52x52 κ receptor 4DJH M1 receptor 5CXV
TM7 276 7.53x53 κ receptor 4DJH κ receptor 4DJH
TM7 277 7.54x54 κ receptor 4DJH ETB receptor 5X93
TM7 278 7.55x55 κ receptor 4DJH A2A receptor 3VG9
TM7 279 7.56x56 κ receptor 4DJH Rhodopsin 1GZM
H8 280 8.47x47 κ receptor 4DJH - -
H8 281 8.48x48 κ receptor 4DJH ETB receptor 5X93
H8 282 8.49x49 κ receptor 4DJH CCR5 5UIW
H8 283 8.50x50 κ receptor 4DJH κ receptor 4DJH
H8 284 8.51x51 κ receptor 4DJH Y1 receptor 5ZBH
H8 285 8.52x52 κ receptor 4DJH OX2 receptor 5WS3
H8 286 8.53x53 κ receptor 4DJH ETB receptor 5X93
H8 287 8.54x54 κ receptor 4DJH - -
H8 288 8.55x55 κ receptor 4DJH - -
H8 289 8.56x56 κ receptor 4DJH M1 receptor 5CXV
H8 290 8.57x57 κ receptor 4DJH OX2 receptor 5WS3
H8 291 8.58x58 κ receptor 4DJH - -
C-term 292 κ receptor 4DJH κ receptor 4DJH
C-term 293 - - - -
C-term 294 - - - -
C-term 295 - - - -
C-term 296 - - - -