GPR4 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): 1.63 docs)

VERSION

2018-07-10

MAIN TEMPLATE

CCR2 (sequence similarity: 44%) PDB: 5T1A

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 74.4 15.1 10.5
Side-chains 19.7 54.8 25.6

Number of backbone templates: 6
Number of rotamer templates: 38

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5T1A
5ZKP
5ZKQ
4XNW
5UNG
5XSZ
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 7 - - - -
N-term 8 - - - -
N-term 9 - - - -
N-term 10 - - - -
N-term 11 - - - -
TM1 12 1.27x27 CCR2 5T1A - -
TM1 13 1.28x28 CCR2 5T1A δ receptor 4N6H
TM1 14 1.29x29 CCR2 5T1A - -
TM1 15 1.30x30 CCR2 5T1A μ receptor 4DKL
TM1 16 1.31x31 CCR2 5T1A - -
TM1 17 1.32x32 CCR2 5T1A - -
TM1 18 1.33x33 CCR2 5T1A BLT1 receptor 5X33
TM1 19 1.34x34 CCR2 5T1A CXCR4 3ODU
TM1 20 1.35x35 CCR2 5T1A - -
TM1 21 1.36x36 CCR2 5T1A CCR2 5T1A
TM1 22 1.37x37 CCR2 5T1A PAR1 3VW7
TM1 23 1.38x38 CCR2 5T1A CCR2 5T1A
TM1 24 1.39x39 CCR2 5T1A CCR2 5T1A
TM1 25 1.40x40 CCR2 5T1A OX2 receptor 5WS3
TM1 26 1.41x41 CCR2 5T1A M3 receptor 4U15
TM1 27 1.42x42 CCR2 5T1A CCR2 5T1A
TM1 28 1.43x43 CCR2 5T1A 5-HT2C receptor 6BQH
TM1 29 1.44x44 CCR2 5T1A D4 receptor 5WIV
TM1 30 1.45x45 CCR2 5T1A AT1 receptor 4ZUD
TM1 31 1.46x46 CCR2 5T1A CCR2 5T1A
TM1 32 1.47x47 CCR2 5T1A μ receptor 4DKL
TM1 33 1.48x48 CCR2 5T1A BLT1 receptor 5X33
TM1 34 1.49x49 CCR2 5T1A LPA6 receptor 5XSZ
TM1 35 1.50x50 CCR2 5T1A CCR2 5T1A
TM1 36 1.51x51 CCR2 5T1A NOP receptor 5DHG
TM1 37 1.52x52 CCR2 5T1A CCR2 5T1A
TM1 38 1.53x53 CCR2 5T1A PAR2 5NDD
TM1 39 1.54x54 CCR2 5T1A apelin receptor 5VBL
TM1 40 1.55x55 CCR2 5T1A apelin receptor 5VBL
TM1 41 1.56x56 CCR2 5T1A OX2 receptor 5WS3
TM1 42 1.57x57 CCR2 5T1A FFA1 receptor 5TZY
TM1 43 1.58x58 CCR2 5T1A AT1 receptor 4YAY
TM1 44 1.59x59 CCR2 5T1A apelin receptor 5VBL
TM1 45 1.60x60 CCR2 5T1A CXCR4 3ODU
TM1 46 1.61x61 PAF receptor 5ZKP - -
ICL1 47 - - - -
ICL1 48 - - - -
ICL1 49 - - - -
TM2 50 2.37x37 CCR2 5T1A 5-HT2C receptor 6BQH
TM2 51 2.38x38 CCR2 5T1A PAF receptor 5ZKP
TM2 52 2.39x39 CCR2 5T1A Rhodopsin 1GZM
TM2 53 2.40x40 CCR2 5T1A - -
TM2 54 2.41x41 CCR2 5T1A AT1 receptor 4ZUD
TM2 55 2.42x42 CCR2 5T1A CCR2 5T1A
TM2 56 2.43x43 CCR2 5T1A CCR2 5T1A
TM2 57 2.44x44 CCR2 5T1A 5-HT2C receptor 6BQH
TM2 58 2.45x45 CCR2 5T1A CCR2 5T1A
TM2 59 2.46x46 CCR2 5T1A CCR2 5T1A
TM2 60 2.47x47 CCR2 5T1A CXCR4 3ODU
TM2 61 2.48x48 CCR2 5T1A CCR2 5T1A
TM2 62 2.49x49 CCR2 5T1A AT1 receptor 4ZUD
TM2 63 2.50x50 CCR2 5T1A CCR2 5T1A
TM2 64 2.51x51 CCR2 5T1A CCR2 5T1A
TM2 65 2.52x52 CCR2 5T1A CCR2 5T1A
TM2 66 2.53x53 CCR2 5T1A P2Y1 receptor 4XNW
TM2 67 2.54x54 CCR2 5T1A ETB receptor 5X93
TM2 68 2.55x55 CCR2 5T1A US28 4XT1
TM2 69 2.56x56 CCR2 5T1A CCR2 5T1A
TM2 70 2.57x57 CCR2 5T1A CCR2 5T1A
TM2 71 2.58x58 CCR2 5T1A CCR2 5T1A
TM2 72 2.59x59 CCR2 5T1A CCR2 5T1A
TM2 73 2.60x60 CCR2 5T1A CCR2 5T1A
TM2 74 2.61x61 CCR2 5T1A D2 receptor 6CM4
TM2 75 2.62x62 CCR2 5T1A - -
TM2 76 2.63x63 CCR2 5T1A AT1 receptor 4ZUD
TM2 77 2.64x64 CCR2 5T1A NTS1 receptor 4BUO
TM2 78 2.65x65 CCR2 5T1A μ receptor 4DKL
TM2 79 2.66x66 CCR2 5T1A Rhodopsin 1GZM
TM2 80 2.67x67 PAF receptor 5ZKP C5a1 receptor 5O9H
ECL1 81 - - - -
ECL1 82 23.49x49 PAF receptor 5ZKP PAF receptor 5ZKP
ECL1 83 23.50x50 PAF receptor 5ZKP PAF receptor 5ZKP
ECL1 84 23.51x51 PAF receptor 5ZKP PAF receptor 5ZKP
ECL1 85 23.52x52 - - - -
TM3 86 3.21x21 CCR2 5T1A CCR2 5T1A
TM3 87 3.22x22 CCR2 5T1A D4 receptor 5WIV
TM3 88 3.23x23 CCR2 5T1A - -
TM3 89 3.24x24 CCR2 5T1A - -
TM3 90 3.25x25 CCR2 5T1A CCR2 5T1A
TM3 91 3.26x26 CCR2 5T1A CCR2 5T1A
TM3 92 3.27x27 CCR2 5T1A CCR2 5T1A
TM3 93 3.28x28 CCR2 5T1A CCR2 5T1A
TM3 94 3.29x29 CCR2 5T1A Rhodopsin 1GZM
TM3 95 3.30x30 CCR2 5T1A Rhodopsin 1GZM
TM3 96 3.31x31 CCR2 5T1A CXCR4 3ODU
TM3 97 3.32x32 CCR2 5T1A PAF receptor 5ZKP
TM3 98 3.33x33 CCR2 5T1A μ receptor 4DKL
TM3 99 3.34x34 CCR2 5T1A LPA1 receptor 4Z35
TM3 100 3.35x35 CCR2 5T1A AT1 receptor 4ZUD
TM3 101 3.36x36 CCR2 5T1A Y1 receptor 5ZBH
TM3 102 3.37x37 CCR2 5T1A AT1 receptor 4ZUD
TM3 103 3.38x38 CCR2 5T1A Rhodopsin 1GZM
TM3 104 3.39x39 CCR2 5T1A AT1 receptor 4ZUD
TM3 105 3.40x40 CCR2 5T1A CCR2 5T1A
TM3 106 3.41x41 CCR2 5T1A LPA1 receptor 4Z35
TM3 107 3.42x42 CCR2 5T1A CCR2 5T1A
TM3 108 3.43x43 CCR2 5T1A AT1 receptor 4ZUD
TM3 109 3.44x44 CCR2 5T1A μ receptor 4DKL
TM3 110 3.45x45 CCR2 5T1A AT1 receptor 4ZUD
TM3 111 3.46x46 CCR2 5T1A CXCR4 3ODU
TM3 112 3.47x47 CCR2 5T1A AT1 receptor 4ZUD
TM3 113 3.48x48 CCR2 5T1A μ receptor 4DKL
TM3 114 3.49x49 CCR2 5T1A CCR2 5T1A
TM3 115 3.50x50 CCR2 5T1A CCR2 5T1A
TM3 116 3.51x51 CCR2 5T1A CCR2 5T1A
TM3 117 3.52x52 CCR2 5T1A CCR2 5T1A
TM3 118 3.53x53 CCR2 5T1A CCR2 5T1A
TM3 119 3.54x54 CCR2 5T1A CCR5 5UIW
TM3 120 3.55x55 CCR2 5T1A CCR9 5LWE
TM3 121 3.56x56 CCR2 5T1A CCR2 5T1A
ICL2 122 34.50x50 - - - -
ICL2 123 34.51x51 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
ICL2 124 34.52x52 P2Y1 receptor 4XNW CCR9 5LWE
ICL2 125 34.53x53 P2Y1 receptor 4XNW - -
ICL2 126 34.54x54 P2Y1 receptor 4XNW - -
ICL2 127 34.55x55 P2Y1 receptor 4XNW C5a1 receptor 5O9H
ICL2 128 34.56x56 P2Y1 receptor 4XNW A2A receptor 3VG9
ICL2 129 34.57x57 - - - -
TM4 130 4.38x38 CCR2 5T1A FFA1 receptor 5TZY
TM4 131 4.39x39 CCR2 5T1A CCR2 5T1A
TM4 132 4.40x40 CCR2 5T1A OX2 receptor 5WS3
TM4 133 4.41x41 CCR2 5T1A 5-HT2B receptor 4IB4
TM4 134 4.42x42 CCR2 5T1A AT1 receptor 4ZUD
TM4 135 4.43x43 CCR2 5T1A CCR2 5T1A
TM4 136 4.44x44 CCR2 5T1A NOP receptor 5DHG
TM4 137 4.45x45 CCR2 5T1A CXCR4 3ODU
TM4 138 4.46x46 CCR2 5T1A CCR2 5T1A
TM4 139 4.47x47 CCR2 5T1A D2 receptor 6CM4
TM4 140 4.48x48 CCR2 5T1A apelin receptor 5VBL
TM4 141 4.49x49 CCR2 5T1A CXCR4 3ODU
TM4 142 4.50x50 CCR2 5T1A CCR2 5T1A
TM4 143 4.51x51 CCR2 5T1A NOP receptor 5DHG
TM4 144 4.52x52 CCR2 5T1A - -
TM4 145 4.53x53 CCR2 5T1A - -
TM4 146 4.54x54 CCR2 5T1A CXCR4 3ODU
TM4 147 4.55x55 CCR2 5T1A δ receptor 4N6H
TM4 148 4.56x56 CCR2 5T1A CCR2 5T1A
TM4 149 4.57x57 PAF receptor 5ZKP - -
TM4 150 4.58x58 PAF receptor 5ZKP PAF receptor 5ZKP
TM4 151 4.59x59 PAF receptor 5ZKP D4 receptor 5WIV
TM4 152 4.60x60 CCR2 5T1A CCR2 5T1A
TM4 153 4.61x61 CCR2 5T1A D2 receptor 6CM4
TM4 154 4.62x62 CCR2 5T1A CXCR4 3ODU
TM4 155 4.63x63 CCR2 5T1A - -
ECL2 156 - - - -
ECL2 157 AT2 receptor 5UNG - -
ECL2 158 AT2 receptor 5UNG - -
ECL2 159 AT2 receptor 5UNG - -
ECL2 160 AT2 receptor 5UNG - -
ECL2 161 AT2 receptor 5UNG - -
ECL2 162 AT2 receptor 5UNG - -
ECL2 163 AT2 receptor 5UNG - -
ECL2 164 AT2 receptor 5UNG - -
ECL2 165 AT2 receptor 5UNG - -
ECL2 166 AT2 receptor 5UNG - -
ECL2 167 - - - -
ECL2 168 45.50x50 CCR2 5T1A CCR2 5T1A
ECL2 169 45.51x51 CCR2 5T1A M3 receptor 4U15
ECL2 170 45.52x52 CCR2 5T1A OX2 receptor 5WS3
ECL2 171 - - - -
ECL2 172 AT2 receptor 5UNG AT2 receptor 5UNG
ECL2 173 AT2 receptor 5UNG AT2 receptor 5UNG
ECL2 174 AT2 receptor 5UNG - -
ECL2 175 - - - -
TM5 176 5.33x34 CCR2 5T1A CCR2 5T1A
TM5 177 5.34x35 CCR2 5T1A CCR2 5T1A
TM5 178 5.35x36 CCR2 5T1A CXCR4 3ODU
TM5 179 5.36x37 CCR2 5T1A BLT1 receptor 5X33
TM5 180 5.37x38 CCR2 5T1A H1 receptor 3RZE
TM5 181 5.38x39 CCR2 5T1A κ receptor 4DJH
TM5 182 5.39x40 CCR2 5T1A P2Y12 receptor 4NTJ
TM5 183 5.40x41 CCR2 5T1A AT1 receptor 4ZUD
TM5 184 5.41x42 CCR2 5T1A D2 receptor 6CM4
TM5 185 5.42x43 CCR2 5T1A CCR2 5T1A
TM5 186 5.43x44 CCR2 5T1A CCR5 5UIW
TM5 187 5.44x45 CCR2 5T1A BLT1 receptor 5X33
TM5 188 5.45x46 CCR2 5T1A CXCR4 3ODU
TM5 189 5.46x461 CCR2 5T1A CCR2 5T1A
TM5 190 5.47x47 CCR2 5T1A AT1 receptor 4YAY
TM5 191 5.48x48 CCR2 5T1A AT1 receptor 4ZUD
TM5 192 5.49x49 CCR2 5T1A NTS1 receptor 4BUO
TM5 193 5.50x50 CCR2 5T1A CCR2 5T1A
TM5 194 5.51x51 CCR2 5T1A - -
TM5 195 5.52x52 CCR2 5T1A ETB receptor 5X93
TM5 196 5.53x53 CCR2 5T1A OX2 receptor 5WS3
TM5 197 5.54x54 CCR2 5T1A CCR2 5T1A
TM5 198 5.55x55 CCR2 5T1A AT1 receptor 4ZUD
TM5 199 5.56x56 CCR2 5T1A OX2 receptor 5WS3
TM5 200 5.57x57 CCR2 5T1A AT1 receptor 4ZUD
TM5 201 5.58x58 CCR2 5T1A CCR2 5T1A
TM5 202 5.59x59 CCR2 5T1A - -
TM5 203 5.60x60 CCR2 5T1A CCR2 5T1A
TM5 204 5.61x61 CCR2 5T1A CCR2 5T1A
TM5 205 5.62x62 PAF receptor 5ZKQ CCR5 5UIW
TM5 206 5.63x63 PAF receptor 5ZKQ PAF receptor 5ZKQ
TM5 207 5.64x64 PAF receptor 5ZKQ AT1 receptor 4ZUD
TM5 208 5.65x65 PAF receptor 5ZKQ Rhodopsin 1GZM
TM5 209 5.66x66 PAF receptor 5ZKQ δ receptor 4N6H
TM5 210 5.67x67 PAF receptor 5ZKQ - -
ICL3 211 - - - -
ICL3 212 - - - -
ICL3 213 - - - -
ICL3 214 - - - -
TM6 215 6.26x26 AT2 receptor 5UNG - -
TM6 216 6.27x27 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 217 6.28x28 AT2 receptor 5UNG NTS1 receptor 4BUO
TM6 218 6.29x29 AT2 receptor 5UNG Y1 receptor 5ZBH
TM6 219 6.30x30 AT2 receptor 5UNG CXCR4 3ODU
TM6 220 6.31x31 AT2 receptor 5UNG - -
TM6 221 6.32x32 AT2 receptor 5UNG CXCR4 3ODU
TM6 222 6.33x33 CCR2 5T1A AT1 receptor 4ZUD
TM6 223 6.34x34 CCR2 5T1A - -
TM6 224 6.35x35 CCR2 5T1A CCR2 5T1A
TM6 225 6.36x36 CCR2 5T1A CCR5 5UIW
TM6 226 6.37x37 CCR2 5T1A D2 receptor 6CM4
TM6 227 6.38x38 CCR2 5T1A μ receptor 4DKL
TM6 228 6.39x39 CCR2 5T1A Y1 receptor 5ZBH
TM6 229 6.40x40 CCR2 5T1A CXCR4 3ODU
TM6 230 6.41x41 CCR2 5T1A CXCR4 3ODU
TM6 231 6.42x42 CCR2 5T1A μ receptor 4DKL
TM6 232 6.43x43 CCR2 5T1A LPA6 receptor 5XSZ
TM6 233 6.44x44 CCR2 5T1A PAF receptor 5ZKP
TM6 234 6.45x45 CCR2 5T1A 5-HT2C receptor 6BQH
TM6 235 6.46x46 CCR2 5T1A μ receptor 4DKL
TM6 236 6.47x47 CCR2 5T1A CXCR4 3ODU
TM6 237 6.48x48 CCR2 5T1A PAF receptor 5ZKP
TM6 238 6.49x49 CCR2 5T1A CCR5 5UIW
TM6 239 6.50x50 CCR2 5T1A CCR2 5T1A
TM6 240 6.51x51 CCR2 5T1A CCR2 5T1A
TM6 241 6.52x52 CCR2 5T1A apelin receptor 5VBL
TM6 242 6.53x53 CCR2 5T1A BLT1 receptor 5X33
TM6 243 6.54x54 CCR2 5T1A OX2 receptor 5WS3
TM6 244 6.55x55 CCR2 5T1A CCR5 5UIW
TM6 245 6.56x56 CCR2 5T1A CCR2 5T1A
TM6 246 6.57x57 CCR2 5T1A - -
TM6 247 6.58x58 CCR2 5T1A - -
TM6 248 6.59x59 CCR2 5T1A CXCR4 3ODU
TM6 249 6.60x60 CCR2 5T1A - -
TM6 250 6.61x61 CCR2 5T1A AT1 receptor 4ZUD
TM6 251 6.62x62 CCR2 5T1A - -
TM6 252 6.63x63 CCR2 5T1A AT1 receptor 4YAY
TM6 253 6.64x64 CCR2 5T1A AT1 receptor 4ZUD
ECL3 254 - - - -
ECL3 255 LPA6 receptor 5XSZ - -
ECL3 256 - - - -
TM7 257 7.24x23 PAF receptor 5ZKP AT1 receptor 4ZUD
TM7 258 7.25x24 PAF receptor 5ZKP AT1 receptor 4ZUD
TM7 259 7.26x25 CCR2 5T1A - -
TM7 260 7.27x26 CCR2 5T1A CXCR4 3ODU
TM7 261 7.28x27 CCR2 5T1A CXCR4 3ODU
TM7 262 7.29x28 CCR2 5T1A NOP receptor 5DHG
TM7 263 7.30x29 CCR2 5T1A CCR5 5UIW
TM7 264 7.31x30 CCR2 5T1A AT1 receptor 4ZUD
TM7 265 7.32x31 CCR2 5T1A P2Y12 receptor 4NTJ
TM7 266 7.33x32 CCR2 5T1A κ receptor 4DJH
TM7 267 7.34x33 CCR2 5T1A CCR2 5T1A
TM7 268 7.35x34 CCR2 5T1A κ receptor 4DJH
TM7 269 7.36x35 CCR2 5T1A μ receptor 4DKL
TM7 270 7.37x36 CCR2 5T1A P2Y12 receptor 4NTJ
TM7 271 7.38x37 CCR2 5T1A OX2 receptor 5WS3
TM7 272 7.39x38 CCR2 5T1A LPA1 receptor 4Z35
TM7 273 7.40x39 CCR2 5T1A CXCR4 3ODU
TM7 274 7.41x40 CCR2 5T1A C5a1 receptor 5O9H
TM7 275 7.42x41 CCR2 5T1A A1 receptor 5UEN
TM7 276 7.43x42 CCR2 5T1A ETB receptor 5X93
TM7 277 7.44x43 CCR2 5T1A BLT1 receptor 5X33
TM7 278 7.45x45 CCR2 5T1A AT1 receptor 4ZUD
TM7 279 7.46x46 CCR2 5T1A CCR2 5T1A
TM7 280 7.47x47 CCR2 5T1A Rhodopsin 1GZM
TM7 281 7.48x48 CCR2 5T1A OX2 receptor 5WS3
TM7 282 7.49x49 CCR2 5T1A PAR2 5NDD
TM7 283 7.50x50 CCR2 5T1A CCR2 5T1A
TM7 284 7.51x51 CCR2 5T1A CCR2 5T1A
TM7 285 7.52x52 CCR2 5T1A apelin receptor 5VBL
TM7 286 7.53x53 CCR2 5T1A CCR2 5T1A
TM7 287 7.54x54 CCR2 5T1A β2-adrenoceptor 5JQH
TM7 288 7.55x55 CCR2 5T1A 5-HT2C receptor 6BQH
TM7 289 7.56x56 CCR2 5T1A CCR2 5T1A
TM7 290 7.57x57 PAF receptor 5ZKP - -
TM7 291 7.58x58 PAF receptor 5ZKP - -
TM7 292 7.59x59 PAF receptor 5ZKP - -
H8 293 8.50x50 CCR2 5T1A - -
H8 294 8.51x51 CCR2 5T1A CCR2 5T1A
H8 295 8.52x52 CCR2 5T1A - -
H8 296 8.53x53 CCR2 5T1A CCR9 5LWE
H8 297 8.54x54 CCR2 5T1A - -
H8 298 8.55x55 CCR2 5T1A - -
H8 299 8.56x56 CCR2 5T1A CCR9 5LWE
H8 300 8.57x57 CCR2 5T1A OX2 receptor 5WS3
H8 301 8.58x58 CCR2 5T1A apelin receptor 5VBL
H8 302 8.59x59 - - - -
H8 303 8.60x60 - - - -
H8 304 8.61x61 - - - -
H8 305 8.62x62 - - - -
H8 306 8.63x63 - - - -
C-term 307 - - - -
C-term 308 - - - -
C-term 309 - - - -
C-term 310 - - - -
C-term 311 - - - -