GPR87 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): -1.56 docs)

VERSION

2018-07-10

MAIN TEMPLATE

CXCR4 (sequence similarity: 46%) PDB: 3ODU

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 78.7 14.0 7.3
Side-chains 24.6 56.5 18.9

Number of backbone templates: 5
Number of rotamer templates: 38

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3ODU
4NTJ
4PXZ
5XSZ
5UNG
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 33 CXCR4 3ODU CXCR4 3ODU
N-term 34 CXCR4 3ODU CXCR4 3ODU
N-term 35 CXCR4 3ODU CXCR4 3ODU
N-term 36 CXCR4 3ODU CXCR4 3ODU
N-term 37 CXCR4 3ODU CXCR4 3ODU
TM1 38 1.28x28 CXCR4 3ODU - -
TM1 39 1.29x29 CXCR4 3ODU ETB receptor 5X93
TM1 40 1.30x30 CXCR4 3ODU CXCR4 3ODU
TM1 41 1.31x31 CXCR4 3ODU - -
TM1 42 1.32x32 CXCR4 3ODU PAR2 5NDD
TM1 43 1.33x33 CXCR4 3ODU CXCR4 3ODU
TM1 44 1.34x34 CXCR4 3ODU OX2 receptor 5WS3
TM1 45 1.35x35 CXCR4 3ODU CXCR4 3ODU
TM1 46 1.36x36 CXCR4 3ODU CXCR4 3ODU
TM1 47 1.37x37 CXCR4 3ODU C5a1 receptor 5O9H
TM1 48 1.38x38 CXCR4 3ODU CCR5 5UIW
TM1 49 1.39x39 CXCR4 3ODU CXCR4 3ODU
TM1 50 1.40x40 CXCR4 3ODU NTS1 receptor 4BUO
TM1 51 1.41x41 CXCR4 3ODU CXCR4 3ODU
TM1 52 1.42x42 CXCR4 3ODU CXCR4 3ODU
TM1 53 1.43x43 CXCR4 3ODU CXCR4 3ODU
TM1 54 1.44x44 CXCR4 3ODU AT1 receptor 4ZUD
TM1 55 1.45x45 CXCR4 3ODU β2-adrenoceptor 5JQH
TM1 56 1.46x46 CXCR4 3ODU A1 receptor 5UEN
TM1 57 1.47x47 CXCR4 3ODU CXCR4 3ODU
TM1 58 1.48x48 CXCR4 3ODU CCR9 5LWE
TM1 59 1.49x49 CXCR4 3ODU H1 receptor 3RZE
TM1 60 1.50x50 CXCR4 3ODU CXCR4 3ODU
TM1 61 1.51x51 CXCR4 3ODU CXCR4 3ODU
TM1 62 1.52x52 CXCR4 3ODU CXCR4 3ODU
TM1 63 1.53x53 CXCR4 3ODU P2Y12 receptor 4NTJ
TM1 64 1.54x54 CXCR4 3ODU CCR2 5T1A
TM1 65 1.55x55 CXCR4 3ODU apelin receptor 5VBL
TM1 66 1.56x56 CXCR4 3ODU CCR5 5UIW
TM1 67 1.57x57 CXCR4 3ODU M3 receptor 4U15
TM1 68 1.58x58 CXCR4 3ODU apelin receptor 5VBL
TM1 69 1.59x59 CXCR4 3ODU CB1 receptor 5TGZ
TM1 70 1.60x60 CXCR4 3ODU - -
ICL1 71 - - - -
ICL1 72 P2Y12 receptor 4NTJ - -
ICL1 73 - - - -
TM2 74 2.37x37 CXCR4 3ODU CCR9 5LWE
TM2 75 2.38x38 CXCR4 3ODU apelin receptor 5VBL
TM2 76 2.39x39 CXCR4 3ODU P2Y12 receptor 4NTJ
TM2 77 2.40x40 CXCR4 3ODU P2Y12 receptor 4NTJ
TM2 78 2.41x41 CXCR4 3ODU - -
TM2 79 2.42x42 CXCR4 3ODU CXCR4 3ODU
TM2 80 2.43x43 CXCR4 3ODU CCR5 5UIW
TM2 81 2.44x44 CXCR4 3ODU P2Y12 receptor 4NTJ
TM2 82 2.45x45 CXCR4 3ODU CCR5 5UIW
TM2 83 2.46x46 CXCR4 3ODU - -
TM2 84 2.47x47 CXCR4 3ODU P2Y12 receptor 4NTJ
TM2 85 2.48x48 CXCR4 3ODU CXCR4 3ODU
TM2 86 2.49x49 CXCR4 3ODU CXCR4 3ODU
TM2 87 2.50x50 CXCR4 3ODU CXCR4 3ODU
TM2 88 2.51x51 CXCR4 3ODU CXCR4 3ODU
TM2 89 2.52x52 CXCR4 3ODU H1 receptor 3RZE
TM2 90 2.53x53 CXCR4 3ODU β2-adrenoceptor 5JQH
TM2 91 2.54x54 CXCR4 3ODU κ receptor 4DJH
TM2 92 2.55x55 CXCR4 3ODU CCR5 5UIW
TM2 93 2.56x56 CXCR4 3ODU CXCR4 3ODU
TM2 94 2.57x57 CXCR4 3ODU CB1 receptor 5TGZ
TM2 95 2.58x58 CXCR4 3ODU CXCR4 3ODU
TM2 96 2.59x59 CXCR4 3ODU CXCR4 3ODU
TM2 97 2.60x60 CXCR4 3ODU LPA6 receptor 5XSZ
TM2 98 2.61x61 CXCR4 3ODU H1 receptor 3RZE
TM2 99 2.62x62 CXCR4 3ODU CXCR4 3ODU
TM2 100 2.63x63 CXCR4 3ODU β2-adrenoceptor 5JQH
TM2 101 2.64x64 CXCR4 3ODU OX2 receptor 5WS3
TM2 102 2.65x65 CXCR4 3ODU CCR5 5UIW
TM2 103 2.66x66 CXCR4 3ODU A2A receptor 5IU4
ECL1 104 - - - -
ECL1 105 - - - -
ECL1 106 23.49x49 LPA6 receptor 5XSZ NTS1 receptor 4BUO
ECL1 107 23.50x50 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ECL1 108 23.51x51 LPA6 receptor 5XSZ CXCR4 3ODU
ECL1 109 23.52x52 - - - -
TM3 110 3.21x21 CXCR4 3ODU - -
TM3 111 3.22x22 CXCR4 3ODU A1 receptor 5UEN
TM3 112 3.23x23 CXCR4 3ODU μ receptor 4DKL
TM3 113 3.24x24 CXCR4 3ODU CXCR4 3ODU
TM3 114 3.25x25 CXCR4 3ODU CXCR4 3ODU
TM3 115 3.26x26 CXCR4 3ODU NTS1 receptor 4BUO
TM3 116 3.27x27 CXCR4 3ODU - -
TM3 117 3.28x28 CXCR4 3ODU P2Y12 receptor 4NTJ
TM3 118 3.29x29 CXCR4 3ODU apelin receptor 5VBL
TM3 119 3.30x30 CXCR4 3ODU CXCR4 3ODU
TM3 120 3.31x31 CXCR4 3ODU CCR5 5UIW
TM3 121 3.32x32 CXCR4 3ODU P2Y12 receptor 4NTJ
TM3 122 3.33x33 CXCR4 3ODU κ receptor 4DJH
TM3 123 3.34x34 CXCR4 3ODU NTS1 receptor 4BUO
TM3 124 3.35x35 CXCR4 3ODU CXCR4 3ODU
TM3 125 3.36x36 CXCR4 3ODU apelin receptor 5VBL
TM3 126 3.37x37 CXCR4 3ODU CXCR4 3ODU
TM3 127 3.38x38 CXCR4 3ODU κ receptor 4DJH
TM3 128 3.39x39 CXCR4 3ODU CXCR4 3ODU
TM3 129 3.40x40 CXCR4 3ODU CCR5 5UIW
TM3 130 3.41x41 CXCR4 3ODU - -
TM3 131 3.42x42 CXCR4 3ODU CCR5 5UIW
TM3 132 3.43x43 CXCR4 3ODU CXCR4 3ODU
TM3 133 3.44x44 CXCR4 3ODU P2Y12 receptor 4NTJ
TM3 134 3.45x45 CXCR4 3ODU CCR5 5UIW
TM3 135 3.46x46 CXCR4 3ODU CXCR4 3ODU
TM3 136 3.47x47 CXCR4 3ODU CXCR4 3ODU
TM3 137 3.48x48 CXCR4 3ODU CCR5 5UIW
TM3 138 3.49x49 CXCR4 3ODU CXCR4 3ODU
TM3 139 3.50x50 CXCR4 3ODU CXCR4 3ODU
TM3 140 3.51x51 CXCR4 3ODU CXCR4 3ODU
TM3 141 3.52x52 CXCR4 3ODU CXCR4 3ODU
TM3 142 3.53x53 CXCR4 3ODU P2Y12 receptor 4NTJ
TM3 143 3.54x54 CXCR4 3ODU CCR5 5UIW
TM3 144 3.55x55 CXCR4 3ODU CXCR4 3ODU
TM3 145 3.56x56 CXCR4 3ODU C5a1 receptor 5O9H
ICL2 146 34.50x50 - - - -
ICL2 147 34.51x51 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 148 34.52x52 LPA6 receptor 5XSZ FFA1 receptor 5TZY
ICL2 149 34.53x53 LPA6 receptor 5XSZ - -
ICL2 150 34.54x54 LPA6 receptor 5XSZ 5-HT1B receptor 4IAQ
ICL2 151 34.55x55 LPA6 receptor 5XSZ C5a1 receptor 5O9H
ICL2 152 34.56x56 LPA6 receptor 5XSZ - -
ICL2 153 34.57x57 - - - -
TM4 154 4.38x38 CXCR4 3ODU 5-HT2C receptor 6BQH
TM4 155 4.39x39 CXCR4 3ODU - -
TM4 156 4.40x40 CXCR4 3ODU CCR5 5UIW
TM4 157 4.41x41 CXCR4 3ODU CCR5 5UIW
TM4 158 4.42x42 CXCR4 3ODU NTS1 receptor 4BUO
TM4 159 4.43x43 CXCR4 3ODU CXCR4 3ODU
TM4 160 4.44x44 CXCR4 3ODU CXCR4 3ODU
TM4 161 4.45x45 CXCR4 3ODU BLT1 receptor 5X33
TM4 162 4.46x46 CXCR4 3ODU CCR5 5UIW
TM4 163 4.47x47 CXCR4 3ODU CXCR4 3ODU
TM4 164 4.48x48 CXCR4 3ODU κ receptor 4DJH
TM4 165 4.49x49 CXCR4 3ODU CXCR4 3ODU
TM4 166 4.50x50 CXCR4 3ODU CXCR4 3ODU
TM4 167 4.51x51 CXCR4 3ODU CCR5 5UIW
TM4 168 4.52x52 CXCR4 3ODU 5-HT2C receptor 6BQH
TM4 169 4.53x53 CXCR4 3ODU P2Y12 receptor 4NTJ
TM4 170 4.54x54 CXCR4 3ODU CCR9 5LWE
TM4 171 4.55x55 CXCR4 3ODU NOP receptor 5DHG
TM4 172 4.56x56 CXCR4 3ODU CXCR4 3ODU
TM4 173 4.57x57 CXCR4 3ODU CCR5 5UIW
TM4 174 4.58x59 CXCR4 3ODU CCR5 5UIW
TM4 175 4.59x60 CXCR4 3ODU CXCR4 3ODU
TM4 176 4.60x61 CXCR4 3ODU CCR5 5UIW
TM4 177 4.61x62 CXCR4 3ODU CCR5 5UIW
TM4 178 4.62x63 CXCR4 3ODU CXCR4 3ODU
TM4 179 4.63x64 CXCR4 3ODU apelin receptor 5VBL
TM4 180 4.64x65 CXCR4 3ODU CCR5 5UIW
ECL2 181 CXCR4 3ODU CXCR4 3ODU
ECL2 182 CXCR4 3ODU - -
ECL2 183 CXCR4 3ODU - -
ECL2 184 CXCR4 3ODU - -
ECL2 185 CXCR4 3ODU - -
ECL2 186 CXCR4 3ODU - -
ECL2 187 CXCR4 3ODU CXCR4 3ODU
ECL2 188 CXCR4 3ODU - -
ECL2 189 CXCR4 3ODU - -
ECL2 190 CXCR4 3ODU - -
ECL2 191 - - - -
ECL2 192 45.50x50 CXCR4 3ODU CXCR4 3ODU
ECL2 193 45.51x51 CXCR4 3ODU CCR5 5UIW
ECL2 194 45.52x52 CXCR4 3ODU - -
ECL2 195 - - - -
ECL2 196 - - - -
ECL2 197 - - - -
TM5 198 5.30x30 P2Y12 receptor 4NTJ - -
TM5 199 5.31x31 P2Y12 receptor 4NTJ - -
TM5 200 5.32x32 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
TM5 201 5.33x33 CXCR4 3ODU PAR2 5NDD
TM5 202 5.34x34 CXCR4 3ODU - -
TM5 203 5.35x35 CXCR4 3ODU CXCR4 3ODU
TM5 204 5.36x36 CXCR4 3ODU P2Y12 receptor 4NTJ
TM5 205 5.37x37 CXCR4 3ODU δ receptor 4N6H
TM5 206 5.38x38 CXCR4 3ODU C5a1 receptor 5O9H
TM5 207 5.39x39 CXCR4 3ODU NTS1 receptor 4BUO
TM5 208 5.40x40 CXCR4 3ODU CCR5 5UIW
TM5 209 5.41x41 CXCR4 3ODU P2Y12 receptor 4NTJ
TM5 210 5.42x42 CXCR4 3ODU NTS1 receptor 4BUO
TM5 211 5.43x43 CXCR4 3ODU NTS1 receptor 4BUO
TM5 212 5.44x44 CXCR4 3ODU β2-adrenoceptor 5JQH
TM5 213 5.45x45 CXCR4 3ODU - -
TM5 214 5.46x46 P2Y12 receptor 4NTJ CCR5 5UIW
TM5 215 5.47x47 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
TM5 216 5.48x48 CXCR4 3ODU CCR5 5UIW
TM5 217 5.49x49 CXCR4 3ODU OX2 receptor 5WS3
TM5 218 5.50x50 CXCR4 3ODU PAF receptor 5ZKP
TM5 219 5.51x51 CXCR4 3ODU CCR5 5UIW
TM5 220 5.52x52 CXCR4 3ODU β2-adrenoceptor 5JQH
TM5 221 5.53x53 CXCR4 3ODU CCR2 5T1A
TM5 222 5.54x54 CXCR4 3ODU C5a1 receptor 5O9H
TM5 223 5.55x55 CXCR4 3ODU κ receptor 4DJH
TM5 224 5.56x56 CXCR4 3ODU A2A receptor 3VG9
TM5 225 5.57x57 CXCR4 3ODU CXCR4 3ODU
TM5 226 5.58x58 CXCR4 3ODU CXCR4 3ODU
TM5 227 5.59x59 CXCR4 3ODU M4 receptor 5DSG
TM5 228 5.60x60 CXCR4 3ODU D4 receptor 5WIV
TM5 229 5.61x61 CXCR4 3ODU CXCR4 3ODU
TM5 230 5.62x62 CXCR4 3ODU BLT1 receptor 5X33
TM5 231 5.63x63 CXCR4 3ODU OX2 receptor 5WS3
TM5 232 5.64x64 CXCR4 3ODU LPA1 receptor 4Z35
TM5 233 5.65x65 P2Y12 receptor 4NTJ apelin receptor 5VBL
TM5 234 5.66x66 P2Y12 receptor 4NTJ CB1 receptor 5TGZ
TM5 235 5.67x67 P2Y12 receptor 4NTJ A1 receptor 5UEN
TM5 236 5.68x68 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
ICL3 237 - - - -
ICL3 238 - - - -
ICL3 239 - - - -
ICL3 240 - - - -
TM6 241 6.24x24 AT2 receptor 5UNG - -
TM6 242 6.25x25 AT2 receptor 5UNG A2A receptor 3VG9
TM6 243 6.26x26 AT2 receptor 5UNG OX2 receptor 5WS3
TM6 244 6.27x27 AT2 receptor 5UNG Y1 receptor 5ZBH
TM6 245 6.28x28 AT2 receptor 5UNG CCR9 5LWE
TM6 246 6.29x29 AT2 receptor 5UNG H1 receptor 3RZE
TM6 247 6.30x30 CXCR4 3ODU CXCR4 3ODU
TM6 248 6.31x31 CXCR4 3ODU CXCR4 3ODU
TM6 249 6.32x32 CXCR4 3ODU CXCR4 3ODU
TM6 250 6.33x33 CXCR4 3ODU - -
TM6 251 6.34x34 CXCR4 3ODU Y1 receptor 5ZBH
TM6 252 6.35x35 CXCR4 3ODU M3 receptor 4U15
TM6 253 6.36x36 CXCR4 3ODU A2A receptor 3VG9
TM6 254 6.37x37 CXCR4 3ODU CCR5 5UIW
TM6 255 6.38x38 CXCR4 3ODU NTS1 receptor 4BUO
TM6 256 6.39x39 CXCR4 3ODU apelin receptor 5VBL
TM6 257 6.40x40 CXCR4 3ODU CCR9 5LWE
TM6 258 6.41x41 CXCR4 3ODU apelin receptor 5VBL
TM6 259 6.42x42 CXCR4 3ODU κ receptor 4DJH
TM6 260 6.43x43 CXCR4 3ODU CCR5 5UIW
TM6 261 6.44x44 CXCR4 3ODU CXCR4 3ODU
TM6 262 6.45x45 CXCR4 3ODU CXCR4 3ODU
TM6 263 6.46x46 CXCR4 3ODU - -
TM6 264 6.47x47 CXCR4 3ODU CXCR4 3ODU
TM6 265 6.48x48 CXCR4 3ODU P2Y12 receptor 4NTJ
TM6 266 6.49x49 CXCR4 3ODU CXCR4 3ODU
TM6 267 6.50x50 CXCR4 3ODU CXCR4 3ODU
TM6 268 6.51x51 CXCR4 3ODU CXCR4 3ODU
TM6 269 6.52x52 CXCR4 3ODU apelin receptor 5VBL
TM6 270 6.53x53 CXCR4 3ODU apelin receptor 5VBL
TM6 271 6.54x54 CXCR4 3ODU - -
TM6 272 6.55x55 CXCR4 3ODU NTS1 receptor 4BUO
TM6 273 6.56x56 CXCR4 3ODU μ receptor 4DKL
TM6 274 6.57x57 CXCR4 3ODU P2Y12 receptor 4NTJ
TM6 275 6.58x58 CXCR4 3ODU NTS1 receptor 4BUO
TM6 276 6.59x59 CXCR4 3ODU CCR5 5UIW
TM6 277 6.60x60 CXCR4 3ODU CXCR4 3ODU
TM6 278 6.61x61 CXCR4 3ODU P2Y12 receptor 4PXZ
TM6 279 6.62x62 CXCR4 3ODU - -
TM6 280 6.63x63 CXCR4 3ODU CXCR4 3ODU
TM6 281 6.64x64 CXCR4 3ODU P2Y1 receptor 4XNW
ECL3 282 - - - -
ECL3 283 P2Y12 receptor 4PXZ - -
ECL3 284 - - - -
TM7 285 7.24x23 CXCR4 3ODU AT1 receptor 4ZUD
TM7 286 7.25x24 CXCR4 3ODU - -
TM7 287 7.26x25 CXCR4 3ODU CCR5 5UIW
TM7 288 7.27x26 CXCR4 3ODU P2Y12 receptor 4NTJ
TM7 289 7.28x27 CXCR4 3ODU 5-HT2C receptor 6BQH
TM7 290 7.29x28 CXCR4 3ODU 5-HT2C receptor 6BQH
TM7 291 7.30x29 CXCR4 3ODU AT1 receptor 4ZUD
TM7 292 7.31x30 CXCR4 3ODU CCR5 5UIW
TM7 293 7.32x31 CXCR4 3ODU OX2 receptor 5WS3
TM7 294 7.33x32 CXCR4 3ODU NTS1 receptor 4BUO
TM7 295 7.34x33 CXCR4 3ODU CCR9 5LWE
TM7 296 7.35x34 CXCR4 3ODU P2Y12 receptor 4NTJ
TM7 297 7.36x35 CXCR4 3ODU S1P1 receptor 3V2Y
TM7 298 7.37x36 CXCR4 3ODU CXCR4 3ODU
TM7 299 7.38x37 CXCR4 3ODU CXCR4 3ODU
TM7 300 7.39x38 CXCR4 3ODU S1P1 receptor 3V2Y
TM7 301 7.40x39 CXCR4 3ODU A1 receptor 5UEN
TM7 302 7.41x40 CXCR4 3ODU CXCR4 3ODU
TM7 303 7.42x41 CXCR4 3ODU apelin receptor 5VBL
TM7 304 7.43x42 CXCR4 3ODU FFA1 receptor 5TZY
TM7 305 7.44x43 CXCR4 3ODU US28 4XT1
TM7 306 7.45x45 CXCR4 3ODU apelin receptor 5VBL
TM7 307 7.46x46 CXCR4 3ODU FFA1 receptor 5TZY
TM7 308 7.47x47 CXCR4 3ODU CXCR4 3ODU
TM7 309 7.48x48 CXCR4 3ODU CXCR4 3ODU
TM7 310 7.49x49 CXCR4 3ODU LPA6 receptor 5XSZ
TM7 311 7.50x50 CXCR4 3ODU CXCR4 3ODU
TM7 312 7.51x51 CXCR4 3ODU CXCR4 3ODU
TM7 313 7.52x52 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
TM7 314 7.53x53 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
TM7 315 7.54x54 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
TM7 316 7.55x55 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
TM7 317 7.56x56 P2Y12 receptor 4NTJ Rhodopsin 1GZM
H8 318 8.47x47 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
H8 319 8.48x48 P2Y12 receptor 4NTJ A2A receptor 3VG9
H8 320 8.49x49 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
H8 321 8.50x50 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
H8 322 8.51x51 P2Y12 receptor 4NTJ LPA1 receptor 4Z35
H8 323 8.52x52 P2Y12 receptor 4NTJ CCR2 5T1A
H8 324 8.53x53 P2Y12 receptor 4NTJ - -
H8 325 8.54x54 P2Y12 receptor 4NTJ CCR5 5UIW
H8 326 8.55x55 P2Y12 receptor 4NTJ - -
H8 327 8.56x56 P2Y12 receptor 4NTJ CCR9 5LWE
H8 328 8.57x57 P2Y12 receptor 4NTJ - -
C-term 329 - - - -
C-term 330 - - - -
C-term 331 - - - -
C-term 332 - - - -
C-term 333 - - - -