kisspeptin receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): -1.36 docs)

VERSION

2018-07-10

MAIN TEMPLATE

κ receptor (sequence similarity: 54%) PDB: 4DJH

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 79.0 11.0 10.0
Side-chains 28.1 50.3 21.6

Number of backbone templates: 5
Number of rotamer templates: 37

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4DJH
6B73
4ZJ8
3SN6
4UHR
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 35 - - - -
N-term 36 - - - -
N-term 37 - - - -
N-term 38 κ receptor 4DJH κ receptor 4DJH
N-term 39 κ receptor 4DJH κ receptor 4DJH
TM1 40 1.30x30 κ receptor 4DJH μ receptor 4DKL
TM1 41 1.31x31 κ receptor 4DJH - -
TM1 42 1.32x32 κ receptor 4DJH μ receptor 4DKL
TM1 43 1.33x33 κ receptor 4DJH OX1 receptor 4ZJ8
TM1 44 1.34x34 κ receptor 4DJH CCR5 5UIW
TM1 45 1.35x35 κ receptor 4DJH NTS1 receptor 4BUO
TM1 46 1.36x36 κ receptor 4DJH AT1 receptor 4ZUD
TM1 47 1.37x37 κ receptor 4DJH Y1 receptor 5ZBH
TM1 48 1.38x38 κ receptor 4DJH - -
TM1 49 1.39x39 κ receptor 4DJH C5a1 receptor 5O9H
TM1 50 1.40x40 κ receptor 4DJH C5a1 receptor 5O9H
TM1 51 1.41x41 κ receptor 4DJH NOP receptor 5DHG
TM1 52 1.42x42 κ receptor 4DJH D4 receptor 5WIV
TM1 53 1.43x43 κ receptor 4DJH BLT1 receptor 5X33
TM1 54 1.44x44 κ receptor 4DJH CXCR4 3ODU
TM1 55 1.45x45 κ receptor 4DJH Y1 receptor 5ZBH
TM1 56 1.46x46 κ receptor 4DJH κ receptor 4DJH
TM1 57 1.47x47 κ receptor 4DJH κ receptor 4DJH
TM1 58 1.48x48 κ receptor 4DJH κ receptor 4DJH
TM1 59 1.49x49 κ receptor 4DJH κ receptor 4DJH
TM1 60 1.50x50 κ receptor 4DJH κ receptor 4DJH
TM1 61 1.51x51 κ receptor 4DJH κ receptor 4DJH
TM1 62 1.52x52 κ receptor 4DJH κ receptor 4DJH
TM1 63 1.53x53 κ receptor 4DJH κ receptor 4DJH
TM1 64 1.54x54 κ receptor 4DJH Y1 receptor 5ZBH
TM1 65 1.55x55 κ receptor 4DJH NOP receptor 5DHG
TM1 66 1.56x56 κ receptor 4DJH κ receptor 4DJH
TM1 67 1.57x57 κ receptor 4DJH κ receptor 4DJH
TM1 68 1.58x58 κ receptor 4DJH AT2 receptor 5UNG
TM1 69 1.59x59 κ receptor 4DJH κ receptor 4DJH
TM1 70 1.60x60 κ receptor 4DJH Rhodopsin 1GZM
ICL1 71 12.48x48 κ receptor 4DJH ETB receptor 5X93
ICL1 72 12.49x49 κ receptor 4DJH - -
ICL1 73 12.50x50 κ receptor 4DJH κ receptor 4DJH
ICL1 74 12.51x51 κ receptor 4DJH OX1 receptor 4ZJ8
TM2 75 2.37x37 κ receptor 4DJH κ receptor 4DJH
TM2 76 2.38x38 κ receptor 4DJH OX1 receptor 4ZJ8
TM2 77 2.39x39 κ receptor 4DJH κ receptor 4DJH
TM2 78 2.40x40 κ receptor 4DJH κ receptor 4DJH
TM2 79 2.41x41 κ receptor 4DJH - -
TM2 80 2.42x42 κ receptor 4DJH κ receptor 4DJH
TM2 81 2.43x43 κ receptor 4DJH κ receptor 4DJH
TM2 82 2.44x44 κ receptor 4DJH apelin receptor 5VBL
TM2 83 2.45x45 κ receptor 4DJH κ receptor 4DJH
TM2 84 2.46x46 κ receptor 4DJH κ receptor 4DJH
TM2 85 2.47x47 κ receptor 4DJH κ receptor 4DJH
TM2 86 2.48x48 κ receptor 4DJH D4 receptor 5WIV
TM2 87 2.49x49 κ receptor 4DJH 5-HT1B receptor 4IAQ
TM2 88 2.50x50 κ receptor 4DJH κ receptor 4DJH
TM2 89 2.51x51 κ receptor 4DJH OX1 receptor 4ZJ8
TM2 90 2.52x52 κ receptor 4DJH apelin receptor 5VBL
TM2 91 2.53x53 κ receptor 4DJH AT1 receptor 4ZUD
TM2 92 2.54x54 κ receptor 4DJH NOP receptor 5DHG
TM2 93 2.55x55 OX1 receptor 4ZJ8 NOP receptor 5DHG
TM2 94 2.56x551 OX1 receptor 4ZJ8 - -
TM2 95 2.57x56 OX1 receptor 4ZJ8 OX1 receptor 4ZJ8
TM2 96 2.58x57 κ receptor 4DJH CCR5 5UIW
TM2 97 2.59x58 κ receptor 4DJH κ receptor 4DJH
TM2 98 2.60x59 κ receptor 4DJH κ receptor 4DJH
TM2 99 2.61x60 κ receptor 4DJH OX2 receptor 5WS3
TM2 100 2.62x61 κ receptor 4DJH AT1 receptor 4ZUD
TM2 101 2.63x62 κ receptor 4DJH OX1 receptor 4ZJ8
TM2 102 2.64x63 κ receptor 4DJH D2 receptor 6CM4
TM2 103 2.65x64 κ receptor 4DJH κ receptor 4DJH
TM2 104 2.66x65 κ receptor 4DJH - -
TM2 105 2.67x66 κ receptor 4DJH NOP receptor 5DHG
ECL1 106 - - - -
ECL1 107 23.49x49 κ receptor 4DJH - -
ECL1 108 23.50x50 κ receptor 4DJH κ receptor 4DJH
ECL1 109 23.51x51 κ receptor 4DJH Y1 receptor 5ZBH
ECL1 110 23.52x52 κ receptor 4DJH M2 receptor 3UON
TM3 111 3.21x21 κ receptor 4DJH κ receptor 4DJH
TM3 112 3.22x22 κ receptor 4DJH κ receptor 4DJH
TM3 113 3.23x23 κ receptor 4DJH CXCR4 3ODU
TM3 114 3.24x24 κ receptor 4DJH Y1 receptor 5ZBH
TM3 115 3.25x25 κ receptor 4DJH κ receptor 4DJH
TM3 116 3.26x26 κ receptor 4DJH κ receptor 4DJH
TM3 117 3.27x27 κ receptor 4DJH β2-adrenoceptor 5JQH
TM3 118 3.28x28 κ receptor 4DJH κ receptor 4DJH
TM3 119 3.29x29 κ receptor 4DJH CCR9 5LWE
TM3 120 3.30x30 κ receptor 4DJH OX1 receptor 4ZJ8
TM3 121 3.31x31 κ receptor 4DJH κ receptor 4DJH
TM3 122 3.32x32 κ receptor 4DJH OX1 receptor 4ZJ8
TM3 123 3.33x33 κ receptor 4DJH - -
TM3 124 3.34x34 κ receptor 4DJH OX1 receptor 4ZJ8
TM3 125 3.35x35 κ receptor 4DJH OX1 receptor 4ZJ8
TM3 126 3.36x36 κ receptor 4DJH OX1 receptor 4ZJ8
TM3 127 3.37x37 κ receptor 4DJH A2A receptor 3VG9
TM3 128 3.38x38 κ receptor 4DJH AT1 receptor 4ZUD
TM3 129 3.39x39 κ receptor 4DJH NTS1 receptor 4BUO
TM3 130 3.40x40 κ receptor 4DJH - -
TM3 131 3.41x41 κ receptor 4DJH LPA1 receptor 4Z35
TM3 132 3.42x42 κ receptor 4DJH κ receptor 4DJH
TM3 133 3.43x43 κ receptor 4DJH κ receptor 4DJH
TM3 134 3.44x44 κ receptor 4DJH κ receptor 4DJH
TM3 135 3.45x45 κ receptor 4DJH NOP receptor 5DHG
TM3 136 3.46x46 κ receptor 4DJH κ receptor 4DJH
TM3 137 3.47x47 κ receptor 4DJH κ receptor 4DJH
TM3 138 3.48x48 κ receptor 4DJH κ receptor 4DJH
TM3 139 3.49x49 κ receptor 4DJH κ receptor 4DJH
TM3 140 3.50x50 κ receptor 4DJH κ receptor 4DJH
TM3 141 3.51x51 κ receptor 4DJH OX1 receptor 4ZJ8
TM3 142 3.52x52 κ receptor 4DJH OX1 receptor 4ZJ8
TM3 143 3.53x53 κ receptor 4DJH Rhodopsin 1GZM
TM3 144 3.54x54 κ receptor 4DJH P2Y12 receptor 4NTJ
TM3 145 3.55x55 κ receptor 4DJH AT1 receptor 4ZUD
TM3 146 3.56x56 κ receptor 4DJH FFA1 receptor 5TZY
ICL2 147 34.50x50 - - - -
ICL2 148 34.51x51 κ receptor 6B73 OX1 receptor 4ZJ8
ICL2 149 34.52x52 κ receptor 6B73 A2A receptor 3VG9
ICL2 150 34.53x53 κ receptor 6B73 κ receptor 6B73
ICL2 151 34.54x54 κ receptor 6B73 κ receptor 6B73
ICL2 152 34.55x55 κ receptor 6B73 D3 receptor 3PBL
ICL2 153 34.56x56 κ receptor 6B73 P2Y1 receptor 4XNW
ICL2 154 34.57x57 - - - -
TM4 155 4.38x38 κ receptor 4DJH κ receptor 4DJH
TM4 156 4.39x39 κ receptor 4DJH κ receptor 4DJH
TM4 157 4.40x40 κ receptor 4DJH μ receptor 4DKL
TM4 158 4.41x41 κ receptor 4DJH C5a1 receptor 5O9H
TM4 159 4.42x42 κ receptor 4DJH κ receptor 4DJH
TM4 160 4.43x43 κ receptor 4DJH D4 receptor 5WIV
TM4 161 4.44x44 κ receptor 4DJH NOP receptor 5DHG
TM4 162 4.45x45 κ receptor 4DJH NOP receptor 5DHG
TM4 163 4.46x46 κ receptor 4DJH CCR5 5UIW
TM4 164 4.47x47 κ receptor 4DJH OX1 receptor 4ZJ8
TM4 165 4.48x48 κ receptor 4DJH - -
TM4 166 4.49x49 κ receptor 4DJH κ receptor 4DJH
TM4 167 4.50x50 κ receptor 4DJH κ receptor 4DJH
TM4 168 4.51x51 κ receptor 4DJH δ receptor 4N6H
TM4 169 4.52x52 κ receptor 4DJH - -
TM4 170 4.53x53 κ receptor 4DJH κ receptor 4DJH
TM4 171 4.54x54 κ receptor 4DJH apelin receptor 5VBL
TM4 172 4.55x55 κ receptor 4DJH μ receptor 4DKL
TM4 173 4.56x56 κ receptor 4DJH κ receptor 4DJH
TM4 174 4.57x57 OX1 receptor 4ZJ8 AT1 receptor 4ZUD
TM4 175 4.58x59 OX1 receptor 4ZJ8 D4 receptor 5WIV
TM4 176 4.59x60 κ receptor 4DJH OX1 receptor 4ZJ8
TM4 177 4.60x61 κ receptor 4DJH apelin receptor 5VBL
TM4 178 4.61x62 κ receptor 4DJH Y1 receptor 5ZBH
TM4 179 4.62x63 κ receptor 4DJH OX1 receptor 4ZJ8
TM4 180 4.63x64 κ receptor 4DJH - -
TM4 181 4.64x65 OX1 receptor 4ZJ8 - -
ECL2 182 - - - -
ECL2 183 - - - -
ECL2 184 - - - -
ECL2 185 - - - -
ECL2 186 - - - -
ECL2 187 - - - -
ECL2 188 - - - -
ECL2 189 - - - -
ECL2 190 - - - -
ECL2 191 45.50x50 κ receptor 4DJH κ receptor 4DJH
ECL2 192 45.51x51 κ receptor 4DJH κ receptor 4DJH
ECL2 193 45.52x52 κ receptor 4DJH OX1 receptor 4ZJ8
ECL2 194 - - - -
ECL2 195 - - - -
TM5 196 5.30x31 κ receptor 4DJH - -
TM5 197 5.31x32 κ receptor 4DJH δ receptor 4N6H
TM5 198 5.32x33 κ receptor 4DJH - -
TM5 199 5.33x34 κ receptor 4DJH apelin receptor 5VBL
TM5 200 5.34x35 κ receptor 4DJH AT1 receptor 4ZUD
TM5 201 5.35x36 κ receptor 4DJH μ receptor 4DKL
TM5 202 5.36x37 κ receptor 4DJH D4 receptor 5WIV
TM5 203 5.37x38 κ receptor 4DJH β2-adrenoceptor 5JQH
TM5 204 5.38x39 κ receptor 4DJH NOP receptor 5DHG
TM5 205 5.39x40 κ receptor 4DJH NOP receptor 5DHG
TM5 206 5.40x41 κ receptor 4DJH AT1 receptor 4ZUD
TM5 207 5.41x42 κ receptor 4DJH D4 receptor 5WIV
TM5 208 5.42x43 κ receptor 4DJH A2A receptor 3VG9
TM5 209 5.43x44 κ receptor 4DJH Y1 receptor 5ZBH
TM5 210 5.44x45 κ receptor 4DJH NOP receptor 5DHG
TM5 211 5.45x46 κ receptor 4DJH A2A receptor 3VG9
TM5 212 5.46x461 κ receptor 4DJH FFA1 receptor 5TZY
TM5 213 5.47x47 κ receptor 4DJH OX1 receptor 4ZJ8
TM5 214 5.48x48 κ receptor 4DJH OX1 receptor 4ZJ8
TM5 215 5.49x49 κ receptor 4DJH CCR5 5UIW
TM5 216 5.50x50 κ receptor 4DJH κ receptor 4DJH
TM5 217 5.51x51 κ receptor 4DJH OX1 receptor 4ZJ8
TM5 218 5.52x52 κ receptor 4DJH κ receptor 4DJH
TM5 219 5.53x53 κ receptor 4DJH - -
TM5 220 5.54x54 κ receptor 4DJH D2 receptor 6CM4
TM5 221 5.55x55 κ receptor 4DJH M1 receptor 5CXV
TM5 222 5.56x56 κ receptor 4DJH BLT1 receptor 5X33
TM5 223 5.57x57 κ receptor 4DJH κ receptor 4DJH
TM5 224 5.58x58 κ receptor 4DJH κ receptor 4DJH
TM5 225 5.59x59 κ receptor 4DJH D3 receptor 3PBL
TM5 226 5.60x60 κ receptor 4DJH D4 receptor 5WIV
TM5 227 5.61x61 κ receptor 4DJH κ receptor 4DJH
TM5 228 5.62x62 κ receptor 4DJH δ receptor 4N6H
TM5 229 5.63x63 κ receptor 4DJH NOP receptor 5DHG
TM5 230 5.64x64 κ receptor 4DJH AT2 receptor 5UNG
TM5 231 5.65x65 κ receptor 4DJH κ receptor 4DJH
TM5 232 5.66x66 κ receptor 4DJH - -
TM5 233 5.67x67 κ receptor 4DJH Y1 receptor 5ZBH
TM5 234 5.68x68 κ receptor 4DJH κ receptor 4DJH
TM5 235 5.69x69 β2-adrenoceptor 3SN6 5-HT2C receptor 6BQH
TM5 236 5.70x70 β2-adrenoceptor 3SN6 P2Y12 receptor 4NTJ
TM5 237 5.71x71 β2-adrenoceptor 3SN6 P2Y12 receptor 4NTJ
TM5 238 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 239 5.73x73 β2-adrenoceptor 3SN6 - -
TM5 240 5.74x74 β2-adrenoceptor 3SN6 - -
ICL3 241 - - - -
ICL3 242 - - - -
ICL3 243 - - - -
ICL3 244 - - - -
ICL3 245 - - - -
ICL3 246 - - - -
ICL3 247 - - - -
ICL3 248 - - - -
TM6 249 6.21x21 A2A receptor 4UHR - -
TM6 250 6.22x22 A2A receptor 4UHR - -
TM6 251 6.23x23 A2A receptor 4UHR A2A receptor 4UHR
TM6 252 6.24x24 A2A receptor 4UHR - -
TM6 253 6.25x25 A2A receptor 4UHR LPA1 receptor 4Z35
TM6 254 6.26x26 A2A receptor 4UHR 5-HT2C receptor 6BQH
TM6 255 6.27x27 A2A receptor 4UHR CXCR4 3ODU
TM6 256 6.28x28 κ receptor 4DJH 5-HT1B receptor 4IAQ
TM6 257 6.29x29 κ receptor 4DJH - -
TM6 258 6.30x30 κ receptor 4DJH OX1 receptor 4ZJ8
TM6 259 6.31x31 κ receptor 4DJH - -
TM6 260 6.32x32 κ receptor 4DJH OX1 receptor 4ZJ8
TM6 261 6.33x33 κ receptor 4DJH M2 receptor 3UON
TM6 262 6.34x34 κ receptor 4DJH 5-HT2C receptor 6BQH
TM6 263 6.35x35 κ receptor 4DJH κ receptor 4DJH
TM6 264 6.36x36 κ receptor 4DJH κ receptor 4DJH
TM6 265 6.37x37 κ receptor 4DJH κ receptor 4DJH
TM6 266 6.38x38 κ receptor 4DJH A2A receptor 3VG9
TM6 267 6.39x39 κ receptor 4DJH AT1 receptor 4ZUD
TM6 268 6.40x40 κ receptor 4DJH κ receptor 4DJH
TM6 269 6.41x41 κ receptor 4DJH κ receptor 4DJH
TM6 270 6.42x42 κ receptor 4DJH OX1 receptor 4ZJ8
TM6 271 6.43x43 κ receptor 4DJH A2A receptor 3VG9
TM6 272 6.44x44 κ receptor 4DJH κ receptor 4DJH
TM6 273 6.45x45 κ receptor 4DJH OX1 receptor 4ZJ8
TM6 274 6.46x46 κ receptor 4DJH CXCR4 3ODU
TM6 275 6.47x47 κ receptor 4DJH κ receptor 4DJH
TM6 276 6.48x48 κ receptor 4DJH κ receptor 4DJH
TM6 277 6.49x49 κ receptor 4DJH CB1 receptor 5TGZ
TM6 278 6.50x50 κ receptor 4DJH κ receptor 4DJH
TM6 279 6.51x51 κ receptor 4DJH κ receptor 4DJH
TM6 280 6.52x52 κ receptor 4DJH NOP receptor 5DHG
TM6 281 6.53x53 κ receptor 4DJH apelin receptor 5VBL
TM6 282 6.54x54 κ receptor 4DJH κ receptor 4DJH
TM6 283 6.55x55 κ receptor 4DJH CCR5 5UIW
TM6 284 6.56x56 κ receptor 4DJH OX2 receptor 5WS3
TM6 285 6.57x57 κ receptor 4DJH OX1 receptor 4ZJ8
TM6 286 6.58x58 κ receptor 4DJH NOP receptor 5DHG
TM6 287 6.59x59 κ receptor 4DJH κ receptor 4DJH
TM6 288 6.60x60 κ receptor 4DJH κ receptor 4DJH
TM6 289 6.61x61 κ receptor 4DJH κ receptor 4DJH
ECL3 290 - - - -
ECL3 291 OX1 receptor 4ZJ8 - -
ECL3 292 OX1 receptor 4ZJ8 - -
ECL3 293 OX1 receptor 4ZJ8 - -
ECL3 294 OX1 receptor 4ZJ8 - -
ECL3 295 OX1 receptor 4ZJ8 - -
ECL3 296 OX1 receptor 4ZJ8 - -
ECL3 297 - - - -
TM7 298 7.28x27 κ receptor 6B73 NOP receptor 5DHG
TM7 299 7.29x28 κ receptor 6B73 - -
TM7 300 7.30x29 κ receptor 6B73 κ receptor 6B73
TM7 301 7.31x30 κ receptor 4DJH κ receptor 4DJH
TM7 302 7.32x31 κ receptor 4DJH OX1 receptor 4ZJ8
TM7 303 7.33x32 κ receptor 4DJH NOP receptor 5DHG
TM7 304 7.34x33 κ receptor 4DJH Y1 receptor 5ZBH
TM7 305 7.35x34 κ receptor 4DJH P2Y12 receptor 4NTJ
TM7 306 7.36x35 κ receptor 4DJH OX1 receptor 4ZJ8
TM7 307 7.37x36 κ receptor 4DJH - -
TM7 308 7.38x37 κ receptor 4DJH A2A receptor 3VG9
TM7 309 7.39x38 κ receptor 4DJH OX1 receptor 4ZJ8
TM7 310 7.40x39 κ receptor 4DJH AT1 receptor 4ZUD
TM7 311 7.41x40 κ receptor 4DJH ETB receptor 5X93
TM7 312 7.42x41 κ receptor 4DJH apelin receptor 5VBL
TM7 313 7.43x42 κ receptor 4DJH κ receptor 4DJH
TM7 314 7.44x43 κ receptor 4DJH LPA6 receptor 5XSZ
TM7 315 7.45x45 κ receptor 4DJH κ receptor 4DJH
TM7 316 7.46x46 κ receptor 4DJH κ receptor 4DJH
TM7 317 7.47x47 κ receptor 4DJH OX1 receptor 4ZJ8
TM7 318 7.48x48 κ receptor 4DJH κ receptor 4DJH
TM7 319 7.49x49 κ receptor 4DJH κ receptor 4DJH
TM7 320 7.50x50 κ receptor 4DJH κ receptor 4DJH
TM7 321 7.51x51 κ receptor 4DJH AT1 receptor 4ZUD
TM7 322 7.52x52 κ receptor 4DJH κ receptor 4DJH
TM7 323 7.53x53 κ receptor 4DJH κ receptor 4DJH
TM7 324 7.54x54 κ receptor 4DJH κ receptor 4DJH
TM7 325 7.55x55 κ receptor 4DJH κ receptor 4DJH
TM7 326 7.56x56 κ receptor 4DJH κ receptor 4DJH
H8 327 8.47x47 κ receptor 4DJH CCR5 5UIW
H8 328 8.48x48 κ receptor 4DJH - -
H8 329 8.49x49 κ receptor 4DJH - -
H8 330 8.50x50 κ receptor 4DJH κ receptor 4DJH
H8 331 8.51x51 κ receptor 4DJH OX1 receptor 4ZJ8
H8 332 8.52x52 κ receptor 4DJH apelin receptor 5VBL
H8 333 8.53x53 κ receptor 4DJH apelin receptor 5VBL
H8 334 8.54x54 κ receptor 4DJH κ receptor 4DJH
H8 335 8.55x55 κ receptor 4DJH NOP receptor 5DHH
H8 336 8.56x56 κ receptor 4DJH 5-HT2B receptor 4IB4
H8 337 8.57x57 κ receptor 4DJH AT2 receptor 5UNG
H8 338 8.58x58 κ receptor 4DJH κ receptor 4DJH
H8 339 8.59x59 κ receptor 4DJH - -
C-term 340 κ receptor 4DJH κ receptor 4DJH
C-term 341 - - - -
C-term 342 - - - -
C-term 343 - - - -
C-term 344 - - - -