LPA4 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): -1.28 docs)

VERSION

2018-07-10

MAIN TEMPLATE

κ receptor (sequence similarity: 54%) PDB: 4DJH

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 83.4 11.0 5.6
Side-chains 26.6 55.8 17.6

Number of backbone templates: 5
Number of rotamer templates: 36

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4DJH
6B73
5XSZ
5UIW
5UNG
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 32 - - - -
N-term 33 - - - -
N-term 34 - - - -
N-term 35 κ receptor 4DJH κ receptor 4DJH
N-term 36 κ receptor 4DJH κ receptor 4DJH
TM1 37 1.30x30 κ receptor 4DJH CCR9 5LWE
TM1 38 1.31x31 κ receptor 4DJH - -
TM1 39 1.32x32 κ receptor 4DJH PAF receptor 5ZKP
TM1 40 1.33x33 κ receptor 4DJH - -
TM1 41 1.34x34 κ receptor 4DJH CCR5 5UIW
TM1 42 1.35x35 κ receptor 4DJH ETB receptor 5X93
TM1 43 1.36x36 κ receptor 4DJH β2-adrenoceptor 5JQH
TM1 44 1.37x37 κ receptor 4DJH κ receptor 4DJH
TM1 45 1.38x38 κ receptor 4DJH κ receptor 4DJH
TM1 46 1.39x39 κ receptor 4DJH κ receptor 4DJH
TM1 47 1.40x40 κ receptor 4DJH κ receptor 4DJH
TM1 48 1.41x41 κ receptor 4DJH κ receptor 4DJH
TM1 49 1.42x42 κ receptor 4DJH κ receptor 4DJH
TM1 50 1.43x43 κ receptor 4DJH κ receptor 4DJH
TM1 51 1.44x44 κ receptor 4DJH CCR5 5UIW
TM1 52 1.45x45 κ receptor 4DJH apelin receptor 5VBL
TM1 53 1.46x46 κ receptor 4DJH κ receptor 4DJH
TM1 54 1.47x47 κ receptor 4DJH κ receptor 4DJH
TM1 55 1.48x48 κ receptor 4DJH ETB receptor 5X93
TM1 56 1.49x49 κ receptor 4DJH LPA6 receptor 5XSZ
TM1 57 1.50x50 κ receptor 4DJH κ receptor 4DJH
TM1 58 1.51x51 κ receptor 4DJH κ receptor 4DJH
TM1 59 1.52x52 κ receptor 4DJH NTS1 receptor 4BUO
TM1 60 1.53x53 κ receptor 4DJH - -
TM1 61 1.54x54 κ receptor 4DJH apelin receptor 5VBL
TM1 62 1.55x55 κ receptor 4DJH κ receptor 4DJH
TM1 63 1.56x56 κ receptor 4DJH κ receptor 4DJH
TM1 64 1.57x57 κ receptor 4DJH M1 receptor 5CXV
TM1 65 1.58x58 κ receptor 4DJH AT2 receptor 5UNG
TM1 66 1.59x59 κ receptor 4DJH AT1 receptor 4ZUD
TM1 67 1.60x60 κ receptor 4DJH - -
ICL1 68 12.48x48 κ receptor 4DJH AT1 receptor 4YAY
ICL1 69 12.49x49 κ receptor 4DJH μ receptor 4DKL
ICL1 70 12.50x50 κ receptor 4DJH κ receptor 4DJH
ICL1 71 12.51x51 κ receptor 4DJH Rhodopsin 1GZM
TM2 72 2.37x37 κ receptor 4DJH CCR5 5UIW
TM2 73 2.38x38 κ receptor 4DJH LPA6 receptor 5XSZ
TM2 74 2.39x39 κ receptor 4DJH κ receptor 4DJH
TM2 75 2.40x40 κ receptor 4DJH BLT1 receptor 5X33
TM2 76 2.41x41 κ receptor 4DJH κ receptor 4DJH
TM2 77 2.42x42 κ receptor 4DJH AT1 receptor 4ZUD
TM2 78 2.43x43 κ receptor 4DJH κ receptor 4DJH
TM2 79 2.44x44 κ receptor 4DJH β2-adrenoceptor 5JQH
TM2 80 2.45x45 κ receptor 4DJH κ receptor 4DJH
TM2 81 2.46x46 κ receptor 4DJH κ receptor 4DJH
TM2 82 2.47x47 κ receptor 4DJH κ receptor 4DJH
TM2 83 2.48x48 κ receptor 4DJH apelin receptor 5VBL
TM2 84 2.49x49 κ receptor 4DJH CCR5 5UIW
TM2 85 2.50x50 κ receptor 4DJH κ receptor 4DJH
TM2 86 2.51x51 κ receptor 4DJH AT1 receptor 4ZUD
TM2 87 2.52x52 κ receptor 4DJH κ receptor 4DJH
TM2 88 2.53x53 κ receptor 4DJH AT1 receptor 4ZUD
TM2 89 2.54x54 κ receptor 4DJH apelin receptor 5VBL
TM2 90 2.55x55 κ receptor 4DJH US28 4XT1
TM2 91 2.56x56 κ receptor 4DJH κ receptor 4DJH
TM2 92 2.57x57 κ receptor 4DJH AT1 receptor 4ZUD
TM2 93 2.58x58 κ receptor 4DJH κ receptor 4DJH
TM2 94 2.59x59 κ receptor 4DJH κ receptor 4DJH
TM2 95 2.60x60 κ receptor 4DJH PAR1 3VW7
TM2 96 2.61x61 κ receptor 4DJH H1 receptor 3RZE
TM2 97 2.62x62 κ receptor 4DJH LPA1 receptor 4Z35
TM2 98 2.63x63 κ receptor 4DJH AT1 receptor 4ZUD
TM2 99 2.64x64 κ receptor 4DJH A1 receptor 5UEN
TM2 100 2.65x65 κ receptor 4DJH PAR1 3VW7
TM2 101 2.66x66 κ receptor 4DJH CCR2 5T1A
ECL1 102 - - - -
ECL1 103 23.49x49 LPA6 receptor 5XSZ C5a1 receptor 5O9H
ECL1 104 23.50x50 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ECL1 105 23.51x51 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ECL1 106 23.52x52 - - - -
TM3 107 3.21x21 κ receptor 4DJH κ receptor 4DJH
TM3 108 3.22x22 κ receptor 4DJH κ receptor 4DJH
TM3 109 3.23x23 κ receptor 4DJH CCR5 5UIW
TM3 110 3.24x24 κ receptor 4DJH κ receptor 4DJH
TM3 111 3.25x25 κ receptor 4DJH κ receptor 4DJH
TM3 112 3.26x26 κ receptor 4DJH κ receptor 4DJH
TM3 113 3.27x27 κ receptor 4DJH κ receptor 4DJH
TM3 114 3.28x28 κ receptor 4DJH apelin receptor 5VBL
TM3 115 3.29x29 κ receptor 4DJH Rhodopsin 1GZM
TM3 116 3.30x30 κ receptor 4DJH D2 receptor 6CM4
TM3 117 3.31x31 κ receptor 4DJH PAR1 3VW7
TM3 118 3.32x32 κ receptor 4DJH LPA6 receptor 5XSZ
TM3 119 3.33x33 κ receptor 4DJH C5a1 receptor 5O9H
TM3 120 3.34x34 κ receptor 4DJH LPA1 receptor 4Z35
TM3 121 3.35x35 κ receptor 4DJH κ receptor 4DJH
TM3 122 3.36x36 κ receptor 4DJH Y1 receptor 5ZBH
TM3 123 3.37x37 κ receptor 4DJH AT1 receptor 4ZUD
TM3 124 3.38x38 κ receptor 4DJH CCR2 5T1A
TM3 125 3.39x39 κ receptor 4DJH κ receptor 4DJH
TM3 126 3.40x40 κ receptor 4DJH - -
TM3 127 3.41x41 κ receptor 4DJH CCR9 5LWE
TM3 128 3.42x42 κ receptor 4DJH CCR5 5UIW
TM3 129 3.43x43 κ receptor 4DJH κ receptor 4DJH
TM3 130 3.44x44 κ receptor 4DJH κ receptor 4DJH
TM3 131 3.45x45 κ receptor 4DJH AT1 receptor 4ZUD
TM3 132 3.46x46 κ receptor 4DJH CCR9 5LWE
TM3 133 3.47x47 κ receptor 4DJH κ receptor 4DJH
TM3 134 3.48x48 κ receptor 4DJH κ receptor 4DJH
TM3 135 3.49x49 κ receptor 4DJH κ receptor 4DJH
TM3 136 3.50x50 κ receptor 4DJH κ receptor 4DJH
TM3 137 3.51x51 κ receptor 4DJH C5a1 receptor 5O9H
TM3 138 3.52x52 κ receptor 4DJH AT1 receptor 4ZUD
TM3 139 3.53x53 κ receptor 4DJH κ receptor 4DJH
TM3 140 3.54x54 κ receptor 4DJH AT1 receptor 4ZUD
TM3 141 3.55x55 κ receptor 4DJH AT1 receptor 4ZUD
TM3 142 3.56x56 κ receptor 4DJH LPA6 receptor 5XSZ
ICL2 143 34.50x50 - - - -
ICL2 144 34.51x51 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 145 34.52x52 LPA6 receptor 5XSZ CCR9 5LWE
ICL2 146 34.53x53 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 147 34.54x54 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
ICL2 148 34.55x55 LPA6 receptor 5XSZ CCR9 5LWE
ICL2 149 34.56x56 LPA6 receptor 5XSZ CB1 receptor 5TGZ
ICL2 150 34.57x57 - - - -
TM4 151 4.38x38 κ receptor 4DJH κ receptor 4DJH
TM4 152 4.39x39 κ receptor 4DJH apelin receptor 5VBL
TM4 153 4.40x40 κ receptor 4DJH μ receptor 4DKL
TM4 154 4.41x41 κ receptor 4DJH μ receptor 4DKL
TM4 155 4.42x42 κ receptor 4DJH CCR9 5LWE
TM4 156 4.43x43 κ receptor 4DJH apelin receptor 5VBL
TM4 157 4.44x44 κ receptor 4DJH κ receptor 4DJH
TM4 158 4.45x45 κ receptor 4DJH μ receptor 4DKL
TM4 159 4.46x46 κ receptor 4DJH AT1 receptor 4ZUD
TM4 160 4.47x47 κ receptor 4DJH apelin receptor 5VBL
TM4 161 4.48x48 κ receptor 4DJH CXCR4 3ODU
TM4 162 4.49x49 κ receptor 4DJH CXCR4 3ODU
TM4 163 4.50x50 κ receptor 4DJH κ receptor 4DJH
TM4 164 4.51x51 κ receptor 4DJH μ receptor 4DKL
TM4 165 4.52x52 κ receptor 4DJH κ receptor 4DJH
TM4 166 4.53x53 κ receptor 4DJH LPA6 receptor 5XSZ
TM4 167 4.54x54 κ receptor 4DJH CXCR4 3ODU
TM4 168 4.55x55 κ receptor 4DJH κ receptor 4DJH
TM4 169 4.56x56 κ receptor 4DJH LPA6 receptor 5XSZ
TM4 170 4.57x57 κ receptor 4DJH κ receptor 4DJH
TM4 171 4.58x58 κ receptor 4DJH κ receptor 4DJH
TM4 172 4.59x59 κ receptor 4DJH κ receptor 4DJH
TM4 173 4.60x60 κ receptor 4DJH κ receptor 4DJH
TM4 174 4.61x61 κ receptor 4DJH C5a1 receptor 5O9H
TM4 175 4.62x62 κ receptor 4DJH BLT1 receptor 5X33
TM4 176 4.63x63 κ receptor 4DJH NTS1 receptor 4BUO
TM4 177 4.64x64 κ receptor 4DJH P2Y1 receptor 4XNW
ECL2 178 - - - -
ECL2 179 CCR5 5UIW - -
ECL2 180 CCR5 5UIW - -
ECL2 181 CCR5 5UIW - -
ECL2 182 CCR5 5UIW - -
ECL2 183 CCR5 5UIW - -
ECL2 184 CCR5 5UIW - -
ECL2 185 CCR5 5UIW - -
ECL2 186 CCR5 5UIW - -
ECL2 187 - - - -
ECL2 188 45.50x50 κ receptor 4DJH κ receptor 4DJH
ECL2 189 45.51x51 κ receptor 4DJH Y1 receptor 5ZBH
ECL2 190 45.52x52 κ receptor 4DJH OX2 receptor 5WS3
ECL2 191 κ receptor 4DJH - -
ECL2 192 κ receptor 4DJH κ receptor 4DJH
ECL2 193 κ receptor 4DJH - -
ECL2 194 κ receptor 4DJH - -
ECL2 195 κ receptor 4DJH - -
TM5 196 5.30x31 κ receptor 4DJH - -
TM5 197 5.31x32 κ receptor 4DJH - -
TM5 198 5.32x33 κ receptor 4DJH C5a1 receptor 5O9H
TM5 199 5.33x34 κ receptor 4DJH - -
TM5 200 5.34x35 κ receptor 4DJH ETB receptor 5X93
TM5 201 5.35x36 κ receptor 4DJH NTS1 receptor 4BUO
TM5 202 5.36x37 κ receptor 4DJH LPA6 receptor 5XSZ
TM5 203 5.37x38 κ receptor 4DJH - -
TM5 204 5.38x39 κ receptor 4DJH M1 receptor 5CXV
TM5 205 5.39x40 κ receptor 4DJH CCR5 5UIW
TM5 206 5.40x41 κ receptor 4DJH κ receptor 4DJH
TM5 207 5.41x42 κ receptor 4DJH BLT1 receptor 5X33
TM5 208 5.42x43 κ receptor 4DJH CCR5 5UIW
TM5 209 5.43x44 κ receptor 4DJH LPA6 receptor 5XSZ
TM5 210 5.44x45 κ receptor 4DJH Rhodopsin 1GZM
TM5 211 5.45x46 κ receptor 4DJH apelin receptor 5VBL
TM5 212 5.46x461 κ receptor 4DJH AT1 receptor 4ZUD
TM5 213 5.47x47 κ receptor 4DJH κ receptor 4DJH
TM5 214 5.48x48 κ receptor 4DJH μ receptor 4DKL
TM5 215 5.49x49 κ receptor 4DJH κ receptor 4DJH
TM5 216 5.50x50 κ receptor 4DJH κ receptor 4DJH
TM5 217 5.51x51 κ receptor 4DJH CCR5 5UIW
TM5 218 5.52x52 κ receptor 4DJH CXCR4 3ODU
TM5 219 5.53x53 κ receptor 4DJH OX2 receptor 5WS3
TM5 220 5.54x54 κ receptor 4DJH LPA6 receptor 5XSZ
TM5 221 5.55x55 κ receptor 4DJH CCR5 5UIW
TM5 222 5.56x56 κ receptor 4DJH CXCR4 3ODU
TM5 223 5.57x57 κ receptor 4DJH κ receptor 4DJH
TM5 224 5.58x58 κ receptor 4DJH LPA6 receptor 5XSZ
TM5 225 5.59x59 κ receptor 4DJH CCR5 5UIW
TM5 226 5.60x60 κ receptor 4DJH NTS1 receptor 4BUO
TM5 227 5.61x61 κ receptor 4DJH β2-adrenoceptor 5JQH
TM5 228 5.62x62 κ receptor 4DJH δ receptor 4N6H
TM5 229 5.63x63 κ receptor 4DJH NOP receptor 5DHG
TM5 230 5.64x64 κ receptor 4DJH CCR5 5UIW
TM5 231 5.65x65 κ receptor 4DJH κ receptor 4DJH
TM5 232 5.66x66 κ receptor 4DJH δ receptor 4N6H
TM5 233 5.67x67 κ receptor 4DJH A1 receptor 5UEN
TM5 234 5.68x68 κ receptor 4DJH - -
ICL3 235 - - - -
ICL3 236 AT2 receptor 5UNG - -
ICL3 237 - - - -
TM6 238 6.24x24 κ receptor 6B73 - -
TM6 239 6.25x25 κ receptor 6B73 5-HT2B receptor 4IB4
TM6 240 6.26x26 κ receptor 6B73 - -
TM6 241 6.27x27 κ receptor 6B73 CXCR4 3ODU
TM6 242 6.28x28 κ receptor 4DJH - -
TM6 243 6.29x29 κ receptor 4DJH κ receptor 4DJH
TM6 244 6.30x30 κ receptor 4DJH CCR9 5LWE
TM6 245 6.31x31 κ receptor 4DJH Rhodopsin 1GZM
TM6 246 6.32x32 κ receptor 4DJH CCR9 5LWE
TM6 247 6.33x33 κ receptor 4DJH Rhodopsin 1GZM
TM6 248 6.34x34 κ receptor 4DJH apelin receptor 5VBL
TM6 249 6.35x35 κ receptor 4DJH AT1 receptor 4YAY
TM6 250 6.36x36 κ receptor 4DJH μ receptor 4DKL
TM6 251 6.37x37 κ receptor 4DJH AT1 receptor 4ZUD
TM6 252 6.38x38 κ receptor 4DJH - -
TM6 253 6.39x39 κ receptor 4DJH κ receptor 4DJH
TM6 254 6.40x40 κ receptor 4DJH LPA6 receptor 5XSZ
TM6 255 6.41x41 κ receptor 4DJH CCR5 5UIW
TM6 256 6.42x42 κ receptor 4DJH κ receptor 4DJH
TM6 257 6.43x43 κ receptor 4DJH κ receptor 4DJH
TM6 258 6.44x44 κ receptor 4DJH κ receptor 4DJH
TM6 259 6.45x45 κ receptor 4DJH κ receptor 4DJH
TM6 260 6.46x46 κ receptor 4DJH κ receptor 4DJH
TM6 261 6.47x47 κ receptor 4DJH κ receptor 4DJH
TM6 262 6.48x48 κ receptor 4DJH LPA6 receptor 5XSZ
TM6 263 6.49x49 κ receptor 4DJH PAF receptor 5ZKP
TM6 264 6.50x50 κ receptor 4DJH κ receptor 4DJH
TM6 265 6.51x51 κ receptor 4DJH CCR5 5UIW
TM6 266 6.52x52 κ receptor 4DJH CCR5 5UIW
TM6 267 6.53x53 κ receptor 4DJH Rhodopsin 4ZWJ
TM6 268 6.54x54 κ receptor 4DJH CCR5 5UIW
TM6 269 6.55x55 κ receptor 4DJH CCR5 5UIW
TM6 270 6.56x56 κ receptor 4DJH AT1 receptor 4ZUD
TM6 271 6.57x57 κ receptor 4DJH AT1 receptor 4ZUD
TM6 272 6.58x58 κ receptor 4DJH apelin receptor 5VBL
TM6 273 6.59x59 κ receptor 4DJH κ receptor 4DJH
TM6 274 6.60x60 κ receptor 4DJH κ receptor 4DJH
TM6 275 6.61x61 κ receptor 4DJH δ receptor 4N6H
TM6 276 6.62x62 LPA6 receptor 5XSZ P2Y1 receptor 4XNW
TM6 277 6.63x63 LPA6 receptor 5XSZ - -
TM6 278 6.64x64 LPA6 receptor 5XSZ - -
ECL3 279 - - - -
ECL3 280 LPA6 receptor 5XSZ - -
ECL3 281 - - - -
TM7 282 7.24x23 LPA6 receptor 5XSZ CCR5 5UIW
TM7 283 7.25x24 LPA6 receptor 5XSZ LPA6 receptor 5XSZ
TM7 284 7.26x25 LPA6 receptor 5XSZ NTS1 receptor 4BUO
TM7 285 7.27x26 LPA6 receptor 5XSZ NTS1 receptor 4BUO
TM7 286 7.28x27 LPA6 receptor 5XSZ CXCR4 3ODU
TM7 287 7.29x28 LPA6 receptor 5XSZ US28 4XT1
TM7 288 7.30x29 LPA6 receptor 5XSZ μ receptor 4DKL
TM7 289 7.31x30 κ receptor 4DJH κ receptor 4DJH
TM7 290 7.32x31 κ receptor 4DJH C5a1 receptor 5O9H
TM7 291 7.33x32 κ receptor 4DJH CCR9 5LWE
TM7 292 7.34x33 κ receptor 4DJH - -
TM7 293 7.35x34 κ receptor 4DJH κ receptor 4DJH
TM7 294 7.36x35 κ receptor 4DJH AT1 receptor 4ZUD
TM7 295 7.37x36 κ receptor 4DJH AT1 receptor 4ZUD
TM7 296 7.38x37 κ receptor 4DJH AT1 receptor 4ZUD
TM7 297 7.39x38 κ receptor 4DJH S1P1 receptor 3V2Y
TM7 298 7.40x39 κ receptor 4DJH AT1 receptor 4ZUD
TM7 299 7.41x40 κ receptor 4DJH κ receptor 4DJH
TM7 300 7.42x41 κ receptor 4DJH AT1 receptor 4ZUD
TM7 301 7.43x42 κ receptor 4DJH PAR2 5NDD
TM7 302 7.44x43 κ receptor 4DJH BLT1 receptor 5X33
TM7 303 7.45x45 κ receptor 4DJH κ receptor 4DJH
TM7 304 7.46x46 κ receptor 4DJH CCR5 5UIW
TM7 305 7.47x47 κ receptor 4DJH AT1 receptor 4ZUD
TM7 306 7.48x48 κ receptor 4DJH β2-adrenoceptor 5JQH
TM7 307 7.49x49 κ receptor 4DJH LPA6 receptor 5XSZ
TM7 308 7.50x50 κ receptor 4DJH κ receptor 4DJH
TM7 309 7.51x51 κ receptor 4DJH apelin receptor 5VBL
TM7 310 7.52x52 κ receptor 4DJH CCR5 5UIW
TM7 311 7.53x53 κ receptor 4DJH κ receptor 4DJH
TM7 312 7.54x54 κ receptor 4DJH ETB receptor 5X93
TM7 313 7.55x55 κ receptor 4DJH κ receptor 4DJH
TM7 314 7.56x56 κ receptor 4DJH S1P1 receptor 3V2Y
H8 315 8.47x47 κ receptor 4DJH - -
H8 316 8.48x48 κ receptor 4DJH μ receptor 4DKL
H8 317 8.49x49 κ receptor 4DJH P2Y12 receptor 4NTJ
H8 318 8.50x50 κ receptor 4DJH κ receptor 4DJH
H8 319 8.51x51 κ receptor 4DJH Y1 receptor 5ZBH
H8 320 8.52x52 κ receptor 4DJH H1 receptor 3RZE
H8 321 8.53x53 κ receptor 4DJH P2Y12 receptor 4NTJ
H8 322 8.54x54 κ receptor 4DJH κ receptor 4DJH
H8 323 8.55x55 κ receptor 4DJH - -
H8 324 8.56x56 κ receptor 4DJH - -
H8 325 8.57x57 κ receptor 4DJH - -
H8 326 8.58x58 κ receptor 4DJH - -
H8 327 8.59x59 κ receptor 4DJH H1 receptor 3RZE
C-term 328 κ receptor 4DJH κ receptor 4DJH
C-term 329 - - - -
C-term 330 - - - -
C-term 331 - - - -
C-term 332 - - - -