MCH2 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 10.37 docs)

VERSION

2018-07-10

MAIN TEMPLATE

μ receptor (sequence similarity: 46%) PDB: 5C1M

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 76.5 16.5 7.1
Side-chains 21.6 51.9 26.5

Number of backbone templates: 9
Number of rotamer templates: 42

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4N6H
5C1M
5O9H
5NDD
5UIW
5X33
3SN6
4UHR
3VG9
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 19 - - - -
N-term 20 - - - -
N-term 21 - - - -
N-term 22 - - - -
N-term 23 - - - -
TM1 24 1.22x22 δ receptor 4N6H - -
TM1 25 1.23x23 δ receptor 4N6H δ receptor 4N6H
TM1 26 1.24x24 δ receptor 4N6H - -
TM1 27 1.25x25 δ receptor 4N6H β2-adrenoceptor 3P0G
TM1 28 1.26x26 δ receptor 4N6H - -
TM1 29 1.27x27 δ receptor 4N6H - -
TM1 30 1.28x28 δ receptor 4N6H δ receptor 4N6H
TM1 31 1.29x29 μ receptor 5C1M - -
TM1 32 1.30x30 μ receptor 5C1M μ receptor 5C1M
TM1 33 1.31x31 μ receptor 5C1M - -
TM1 34 1.32x32 μ receptor 5C1M PAR2 5NDD
TM1 35 1.33x33 μ receptor 5C1M κ receptor 6B73
TM1 36 1.34x34 μ receptor 5C1M κ receptor 6B73
TM1 37 1.35x35 μ receptor 5C1M 5-HT1B receptor 6G79
TM1 38 1.36x36 μ receptor 5C1M AT2 receptor 5UNG
TM1 39 1.37x37 μ receptor 5C1M PAR1 3VW7
TM1 40 1.38x38 μ receptor 5C1M - -
TM1 41 1.39x39 μ receptor 5C1M 5-HT2C receptor 6BQH
TM1 42 1.40x40 μ receptor 5C1M M2 receptor 4MQT
TM1 43 1.41x41 μ receptor 5C1M μ receptor 5C1M
TM1 44 1.42x42 μ receptor 5C1M β2-adrenoceptor 3SN6
TM1 45 1.43x43 μ receptor 5C1M μ receptor 5C1M
TM1 46 1.44x44 μ receptor 5C1M - -
TM1 47 1.45x45 μ receptor 5C1M CXCR4 3ODU
TM1 48 1.46x46 μ receptor 5C1M μ receptor 5C1M
TM1 49 1.47x47 μ receptor 5C1M μ receptor 5C1M
TM1 50 1.48x48 μ receptor 5C1M κ receptor 6B73
TM1 51 1.49x49 μ receptor 5C1M μ receptor 5C1M
TM1 52 1.50x50 μ receptor 5C1M μ receptor 5C1M
TM1 53 1.51x51 μ receptor 5C1M AT2 receptor 5UNG
TM1 54 1.52x52 μ receptor 5C1M μ receptor 5C1M
TM1 55 1.53x53 μ receptor 5C1M - -
TM1 56 1.54x54 μ receptor 5C1M AT2 receptor 5UNG
TM1 57 1.55x55 μ receptor 5C1M κ receptor 6B73
TM1 58 1.56x56 μ receptor 5C1M NTS1 receptor 5T04
TM1 59 1.57x57 μ receptor 5C1M μ receptor 5C1M
TM1 60 1.58x58 μ receptor 5C1M κ receptor 6B73
TM1 61 1.59x59 μ receptor 5C1M μ receptor 5C1M
TM1 62 1.60x60 μ receptor 5C1M CB1 receptor 5XRA
ICL1 63 - - - -
ICL1 64 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL1 65 - - - -
TM2 66 2.37x37 μ receptor 5C1M μ receptor 5C1M
TM2 67 2.38x38 μ receptor 5C1M β2-adrenoceptor 3SN6
TM2 68 2.39x39 μ receptor 5C1M ETB receptor 5X93
TM2 69 2.40x40 μ receptor 5C1M US28 4XT1
TM2 70 2.41x41 μ receptor 5C1M μ receptor 5C1M
TM2 71 2.42x42 μ receptor 5C1M μ receptor 5C1M
TM2 72 2.43x43 μ receptor 5C1M μ receptor 5C1M
TM2 73 2.44x44 μ receptor 5C1M - -
TM2 74 2.45x45 μ receptor 5C1M μ receptor 5C1M
TM2 75 2.46x46 μ receptor 5C1M μ receptor 5C1M
TM2 76 2.47x47 μ receptor 5C1M μ receptor 5C1M
TM2 77 2.48x48 μ receptor 5C1M AT2 receptor 5UNG
TM2 78 2.49x49 μ receptor 5C1M μ receptor 5C1M
TM2 79 2.50x50 μ receptor 5C1M μ receptor 5C1M
TM2 80 2.51x51 μ receptor 5C1M β2-adrenoceptor 3SN6
TM2 81 2.52x52 μ receptor 5C1M β2-adrenoceptor 3SN6
TM2 82 2.53x53 μ receptor 5C1M ETB receptor 5X93
TM2 83 2.54x54 μ receptor 5C1M ETB receptor 5X93
TM2 84 2.55x55 μ receptor 5C1M M2 receptor 4MQT
TM2 85 2.56x56 μ receptor 5C1M Rhodopsin 4ZWJ
TM2 86 2.57x57 μ receptor 5C1M κ receptor 6B73
TM2 87 2.58x58 μ receptor 5C1M μ receptor 5C1M
TM2 88 2.59x59 μ receptor 5C1M μ receptor 5C1M
TM2 89 2.60x60 μ receptor 5C1M P2Y1 receptor 4XNW
TM2 90 2.61x61 μ receptor 5C1M PAF receptor 5ZKP
TM2 91 2.62x62 μ receptor 5C1M CCR5 5UIW
TM2 92 2.63x63 μ receptor 5C1M - -
TM2 93 2.64x64 μ receptor 5C1M - -
TM2 94 2.65x65 μ receptor 5C1M CCR5 5UIW
TM2 95 2.66x66 μ receptor 5C1M apelin receptor 5VBL
ECL1 96 - - - -
ECL1 97 - - - -
ECL1 98 23.49x49 δ receptor 4N6H CCR2 5T1A
ECL1 99 23.50x50 δ receptor 4N6H δ receptor 4N6H
ECL1 100 23.51x51 δ receptor 4N6H Rhodopsin 4ZWJ
ECL1 101 23.52x52 - - - -
TM3 102 3.21x21 μ receptor 5C1M μ receptor 5C1M
TM3 103 3.22x22 μ receptor 5C1M C5a1 receptor 5O9H
TM3 104 3.23x23 μ receptor 5C1M H1 receptor 3RZE
TM3 105 3.24x24 μ receptor 5C1M μ receptor 5C1M
TM3 106 3.25x25 μ receptor 5C1M μ receptor 5C1M
TM3 107 3.26x26 μ receptor 5C1M US28 4XT1
TM3 108 3.27x27 μ receptor 5C1M μ receptor 5C1M
TM3 109 3.28x28 μ receptor 5C1M A2A receptor 5G53
TM3 110 3.29x29 μ receptor 5C1M β2-adrenoceptor 3SN6
TM3 111 3.30x30 μ receptor 5C1M μ receptor 5C1M
TM3 112 3.31x31 μ receptor 5C1M NTS1 receptor 5T04
TM3 113 3.32x32 μ receptor 5C1M μ receptor 5C1M
TM3 114 3.33x33 μ receptor 5C1M AT2 receptor 5UNG
TM3 115 3.34x34 μ receptor 5C1M PAR1 3VW7
TM3 116 3.35x35 μ receptor 5C1M μ receptor 5C1M
TM3 117 3.36x36 μ receptor 5C1M - -
TM3 118 3.37x37 μ receptor 5C1M μ receptor 5C1M
TM3 119 3.38x38 μ receptor 5C1M β2-adrenoceptor 3SN6
TM3 120 3.39x39 μ receptor 5C1M CCR9 5LWE
TM3 121 3.40x40 μ receptor 5C1M - -
TM3 122 3.41x41 μ receptor 5C1M PAF receptor 5ZKP
TM3 123 3.42x42 μ receptor 5C1M CXCR4 3ODU
TM3 124 3.43x43 μ receptor 5C1M PAR1 3VW7
TM3 125 3.44x44 μ receptor 5C1M κ receptor 6B73
TM3 126 3.45x45 μ receptor 5C1M β2-adrenoceptor 3SN6
TM3 127 3.46x46 μ receptor 5C1M μ receptor 5C1M
TM3 128 3.47x47 μ receptor 5C1M μ receptor 5C1M
TM3 129 3.48x48 μ receptor 5C1M μ receptor 5C1M
TM3 130 3.49x49 μ receptor 5C1M μ receptor 5C1M
TM3 131 3.50x50 μ receptor 5C1M μ receptor 5C1M
TM3 132 3.51x51 μ receptor 5C1M μ receptor 5C1M
TM3 133 3.52x52 μ receptor 5C1M β2-adrenoceptor 3SN6
TM3 134 3.53x53 μ receptor 5C1M μ receptor 5C1M
TM3 135 3.54x54 μ receptor 5C1M - -
TM3 136 3.55x55 μ receptor 5C1M LPA6 receptor 5XSZ
TM3 137 3.56x56 μ receptor 5C1M H1 receptor 3RZE
ICL2 138 34.50x50 - - - -
ICL2 139 34.51x51 δ receptor 4N6H β2-adrenoceptor 3SN6
ICL2 140 34.52x52 δ receptor 4N6H A2A receptor 5G53
ICL2 141 34.53x53 δ receptor 4N6H - -
ICL2 142 34.54x54 δ receptor 4N6H - -
ICL2 143 34.55x55 δ receptor 4N6H Rhodopsin 4ZWJ
ICL2 144 34.56x56 δ receptor 4N6H CCR9 5LWE
ICL2 145 34.57x57 - - - -
TM4 146 4.38x38 μ receptor 5C1M μ receptor 5C1M
TM4 147 4.39x39 μ receptor 5C1M NTS1 receptor 5T04
TM4 148 4.40x40 μ receptor 5C1M - -
TM4 149 4.41x41 μ receptor 5C1M κ receptor 6B73
TM4 150 4.42x42 μ receptor 5C1M NTS1 receptor 5T04
TM4 151 4.43x43 μ receptor 5C1M Rhodopsin 4ZWJ
TM4 152 4.44x44 μ receptor 5C1M - -
TM4 153 4.45x45 μ receptor 5C1M κ receptor 6B73
TM4 154 4.46x46 μ receptor 5C1M μ receptor 5C1M
TM4 155 4.47x47 μ receptor 5C1M β2-adrenoceptor 3SN6
TM4 156 4.48x48 μ receptor 5C1M A1 receptor 6D9H
TM4 157 4.49x49 μ receptor 5C1M apelin receptor 5VBL
TM4 158 4.50x50 μ receptor 5C1M μ receptor 5C1M
TM4 159 4.51x51 μ receptor 5C1M 5-HT2C receptor 6BQG
TM4 160 4.52x52 μ receptor 5C1M NTS1 receptor 5T04
TM4 161 4.53x53 μ receptor 5C1M μ receptor 5C1M
TM4 162 4.54x54 μ receptor 5C1M M2 receptor 4MQT
TM4 163 4.55x55 μ receptor 5C1M M2 receptor 4MQT
TM4 164 4.56x56 μ receptor 5C1M NTS1 receptor 5T04
TM4 165 4.57x57 PAR2 5NDD NTS1 receptor 5T04
TM4 166 4.58x59 PAR2 5NDD β2-adrenoceptor 3SN6
TM4 167 4.59x60 μ receptor 5C1M β2-adrenoceptor 3SN6
TM4 168 4.60x61 μ receptor 5C1M 5-HT2B receptor 5TUD
TM4 169 4.61x62 μ receptor 5C1M - -
TM4 170 4.62x63 μ receptor 5C1M 5-HT2C receptor 6BQG
TM4 171 4.63x64 μ receptor 5C1M - -
TM4 172 4.64x65 CCR5 5UIW - -
ECL2 173 μ receptor 5C1M - -
ECL2 174 μ receptor 5C1M - -
ECL2 175 μ receptor 5C1M - -
ECL2 176 μ receptor 5C1M - -
ECL2 177 μ receptor 5C1M - -
ECL2 178 μ receptor 5C1M - -
ECL2 179 μ receptor 5C1M - -
ECL2 180 μ receptor 5C1M - -
ECL2 181 μ receptor 5C1M - -
ECL2 182 μ receptor 5C1M - -
ECL2 183 - - - -
ECL2 184 45.50x50 μ receptor 5C1M μ receptor 5C1M
ECL2 185 45.51x51 μ receptor 5C1M AT1 receptor 4ZUD
ECL2 186 45.52x52 μ receptor 5C1M β2-adrenoceptor 4LDE
ECL2 187 - - - -
ECL2 188 BLT1 receptor 5X33 BLT1 receptor 5X33
ECL2 189 - - - -
TM5 190 5.31x32 μ receptor 5C1M δ receptor 4N6H
TM5 191 5.32x33 μ receptor 5C1M FFA1 receptor 5TZY
TM5 192 5.33x34 μ receptor 5C1M - -
TM5 193 5.34x35 μ receptor 5C1M PAR2 5NDD
TM5 194 5.35x36 μ receptor 5C1M NTS1 receptor 5T04
TM5 195 5.36x37 μ receptor 5C1M κ receptor 6B73
TM5 196 5.37x38 μ receptor 5C1M H1 receptor 3RZE
TM5 197 5.38x39 μ receptor 5C1M β2-adrenoceptor 3SN6
TM5 198 5.39x40 μ receptor 5C1M M2 receptor 4MQT
TM5 199 5.40x41 μ receptor 5C1M AT2 receptor 5UNG
TM5 200 5.41x42 μ receptor 5C1M Rhodopsin 4ZWJ
TM5 201 5.42x43 μ receptor 5C1M US28 4XT1
TM5 202 5.43x44 μ receptor 5C1M NTS1 receptor 5T04
TM5 203 5.44x45 μ receptor 5C1M μ receptor 5C1M
TM5 204 5.45x46 μ receptor 5C1M BLT1 receptor 5X33
TM5 205 5.46x461 μ receptor 5C1M OX2 receptor 5WS3
TM5 206 5.47x47 μ receptor 5C1M μ receptor 5C1M
TM5 207 5.48x48 μ receptor 5C1M PAF receptor 5ZKP
TM5 208 5.49x49 μ receptor 5C1M NTS1 receptor 5T04
TM5 209 5.50x50 μ receptor 5C1M μ receptor 5C1M
TM5 210 5.51x51 μ receptor 5C1M β2-adrenoceptor 3SN6
TM5 211 5.52x52 μ receptor 5C1M D4 receptor 5WIV
TM5 212 5.53x53 μ receptor 5C1M 5-HT1B receptor 6G79
TM5 213 5.54x54 μ receptor 5C1M μ receptor 5C1M
TM5 214 5.55x55 μ receptor 5C1M PAF receptor 5ZKP
TM5 215 5.56x56 μ receptor 5C1M μ receptor 5C1M
TM5 216 5.57x57 μ receptor 5C1M μ receptor 5C1M
TM5 217 5.58x58 μ receptor 5C1M μ receptor 5C1M
TM5 218 5.59x59 μ receptor 5C1M D2 receptor 6CM4
TM5 219 5.60x60 μ receptor 5C1M μ receptor 5C1M
TM5 220 5.61x61 μ receptor 5C1M AT2 receptor 5UNG
TM5 221 5.62x62 μ receptor 5C1M LPA6 receptor 5XSZ
TM5 222 5.63x63 μ receptor 5C1M ETB receptor 5X93
TM5 223 5.64x64 μ receptor 5C1M LPA1 receptor 4Z35
TM5 224 5.65x65 μ receptor 5C1M C5a1 receptor 5O9H
TM5 225 5.66x66 μ receptor 5C1M OX2 receptor 5WS3
TM5 226 5.67x67 μ receptor 5C1M Rhodopsin 4ZWJ
TM5 227 5.68x68 μ receptor 5C1M - -
TM5 228 5.69x69 β2-adrenoceptor 3SN6 P2Y12 receptor 4NTJ
TM5 229 5.70x70 β2-adrenoceptor 3SN6 β2-adrenoceptor 3SN6
TM5 230 5.71x71 β2-adrenoceptor 3SN6 Rhodopsin 4ZWJ
TM5 231 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 232 5.73x73 β2-adrenoceptor 3SN6 - -
ICL3 233 μ receptor 5C1M - -
ICL3 234 μ receptor 5C1M - -
ICL3 235 μ receptor 5C1M - -
ICL3 236 μ receptor 5C1M - -
ICL3 237 μ receptor 5C1M - -
TM6 238 6.22x22 A2A receptor 4UHR - -
TM6 239 6.23x23 μ receptor 5C1M - -
TM6 240 6.24x24 μ receptor 5C1M - -
TM6 241 6.25x25 μ receptor 5C1M - -
TM6 242 6.26x26 μ receptor 5C1M - -
TM6 243 6.27x27 μ receptor 5C1M - -
TM6 244 6.28x28 μ receptor 5C1M NTS1 receptor 5T04
TM6 245 6.29x29 μ receptor 5C1M 5-HT1B receptor 6G79
TM6 246 6.30x30 μ receptor 5C1M PAF receptor 5ZKP
TM6 247 6.31x31 μ receptor 5C1M LPA1 receptor 4Z35
TM6 248 6.32x32 μ receptor 5C1M β2-adrenoceptor 3P0G
TM6 249 6.33x33 μ receptor 5C1M CB1 receptor 5XRA
TM6 250 6.34x34 μ receptor 5C1M μ receptor 5C1M
TM6 251 6.35x35 μ receptor 5C1M β2-adrenoceptor 3SN6
TM6 252 6.36x36 μ receptor 5C1M μ receptor 5C1M
TM6 253 6.37x37 μ receptor 5C1M μ receptor 5C1M
TM6 254 6.38x38 μ receptor 5C1M μ receptor 5C1M
TM6 255 6.39x39 μ receptor 5C1M μ receptor 5C1M
TM6 256 6.40x40 μ receptor 5C1M apelin receptor 5VBL
TM6 257 6.41x41 μ receptor 5C1M μ receptor 5C1M
TM6 258 6.42x42 μ receptor 5C1M CB1 receptor 5XRA
TM6 259 6.43x43 μ receptor 5C1M μ receptor 5C1M
TM6 260 6.44x44 μ receptor 5C1M μ receptor 5C1M
TM6 261 6.45x45 μ receptor 5C1M μ receptor 5C1M
TM6 262 6.46x46 μ receptor 5C1M β2-adrenoceptor 3SN6
TM6 263 6.47x47 μ receptor 5C1M A1 receptor 6D9H
TM6 264 6.48x48 μ receptor 5C1M - -
TM6 265 6.49x49 μ receptor 5C1M M2 receptor 4MQT
TM6 266 6.50x50 μ receptor 5C1M μ receptor 5C1M
TM6 267 6.51x51 μ receptor 5C1M NTS1 receptor 5T04
TM6 268 6.52x52 μ receptor 5C1M μ receptor 5C1M
TM6 269 6.53x53 μ receptor 5C1M AT2 receptor 5UNG
TM6 270 6.54x54 μ receptor 5C1M 5-HT1B receptor 6G79
TM6 271 6.55x55 μ receptor 5C1M PAF receptor 5ZKP
TM6 272 6.56x56 μ receptor 5C1M κ receptor 6B73
TM6 273 6.57x57 μ receptor 5C1M κ receptor 6B73
TM6 274 6.58x58 μ receptor 5C1M M2 receptor 4MQT
TM6 275 6.59x59 μ receptor 5C1M A1 receptor 6D9H
TM6 276 6.60x60 μ receptor 5C1M - -
TM6 277 6.61x61 μ receptor 5C1M - -
ECL3 278 - - - -
ECL3 279 A2A receptor 3VG9 - -
ECL3 280 A2A receptor 3VG9 - -
ECL3 281 A2A receptor 3VG9 - -
ECL3 282 A2A receptor 3VG9 - -
ECL3 283 - - - -
TM7 284 7.31x30 μ receptor 5C1M - -
TM7 285 7.32x31 μ receptor 5C1M PAR2 5NDD
TM7 286 7.33x32 μ receptor 5C1M μ receptor 5C1M
TM7 287 7.34x33 μ receptor 5C1M - -
TM7 288 7.35x34 μ receptor 5C1M κ receptor 6B73
TM7 289 7.36x35 μ receptor 5C1M κ receptor 6B73
TM7 290 7.37x36 μ receptor 5C1M β2-adrenoceptor 3SN6
TM7 291 7.38x37 μ receptor 5C1M OX2 receptor 5WS3
TM7 292 7.39x38 μ receptor 5C1M μ receptor 5C1M
TM7 293 7.40x39 μ receptor 5C1M PAF receptor 5ZKP
TM7 294 7.41x40 μ receptor 5C1M μ receptor 5C1M
TM7 295 7.42x41 μ receptor 5C1M A2A receptor 5G53
TM7 296 7.43x42 μ receptor 5C1M μ receptor 5C1M
TM7 297 7.44x43 μ receptor 5C1M NTS1 receptor 5T04
TM7 298 7.45x45 μ receptor 5C1M NTS1 receptor 5T04
TM7 299 7.46x46 μ receptor 5C1M μ receptor 5C1M
TM7 300 7.47x47 μ receptor 5C1M κ receptor 6B73
TM7 301 7.48x48 μ receptor 5C1M NTS1 receptor 5T04
TM7 302 7.49x49 μ receptor 5C1M μ receptor 5C1M
TM7 303 7.50x50 μ receptor 5C1M μ receptor 5C1M
TM7 304 7.51x51 δ receptor 4N6H AT2 receptor 5UNG
TM7 305 7.52x52 δ receptor 4N6H δ receptor 4N6H
TM7 306 7.53x53 δ receptor 4N6H δ receptor 4N6H
TM7 307 7.54x54 δ receptor 4N6H Rhodopsin 4ZWJ
TM7 308 7.55x55 δ receptor 4N6H M2 receptor 4MQT
TM7 309 7.56x56 δ receptor 4N6H δ receptor 4N6H
H8 310 8.47x47 δ receptor 4N6H δ receptor 4N6H
H8 311 8.48x48 δ receptor 4N6H OX2 receptor 5WS3
H8 312 8.49x49 δ receptor 4N6H δ receptor 4N6H
H8 313 8.50x50 δ receptor 4N6H β2-adrenoceptor 3SN6
H8 314 8.51x51 δ receptor 4N6H AT2 receptor 5UNF
H8 315 8.52x52 δ receptor 4N6H M2 receptor 3UON
H8 316 8.53x53 δ receptor 4N6H - -
H8 317 8.54x54 δ receptor 4N6H AT2 receptor 5UNG
H8 318 8.55x55 δ receptor 4N6H - -
H8 319 8.56x56 δ receptor 4N6H LPA1 receptor 4Z36
H8 320 8.57x57 δ receptor 4N6H A2A receptor 5G53
H8 321 8.58x58 δ receptor 4N6H - -
H8 322 8.59x59 δ receptor 4N6H 5-HT2C receptor 6BQG
H8 323 8.60x60 δ receptor 4N6H - -
C-term 324 - - - -
C-term 325 - - - -
C-term 326 - - - -
C-term 327 - - - -
C-term 328 - - - -