MRGPRD homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active (Δ distance (Å): 6.29 docs)

VERSION

2018-07-10

MAIN TEMPLATE

AT2 receptor (sequence similarity: 36%) PDB: 5UNG

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 74.6 15.9 9.4
Side-chains 15.6 56.5 27.9

Number of backbone templates: 5
Number of rotamer templates: 42

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5O9H
5UNG
4ZJ8
4XNW
3VG9
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 19 - - - -
N-term 20 - - - -
N-term 21 - - - -
N-term 22 - - - -
N-term 23 - - - -
TM1 24 1.29x29 C5a1 receptor 5O9H - -
TM1 25 1.30x30 C5a1 receptor 5O9H ETB receptor 5X93
TM1 26 1.31x31 C5a1 receptor 5O9H CCR5 5UIW
TM1 27 1.32x32 C5a1 receptor 5O9H PAF receptor 5ZKP
TM1 28 1.33x33 AT2 receptor 5UNG - -
TM1 29 1.34x34 AT2 receptor 5UNG US28 4XT1
TM1 30 1.35x35 AT2 receptor 5UNG Rhodopsin 5DYS
TM1 31 1.36x36 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM1 32 1.37x37 AT2 receptor 5UNG PAR1 3VW7
TM1 33 1.38x38 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 34 1.39x39 AT2 receptor 5UNG M2 receptor 4MQT
TM1 35 1.40x40 AT2 receptor 5UNG apelin receptor 5VBL
TM1 36 1.41x41 AT2 receptor 5UNG M3 receptor 4U15
TM1 37 1.42x42 AT2 receptor 5UNG - -
TM1 38 1.43x43 AT2 receptor 5UNG μ receptor 5C1M
TM1 39 1.44x44 AT2 receptor 5UNG US28 4XT1
TM1 40 1.45x45 AT2 receptor 5UNG - -
TM1 41 1.46x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 42 1.47x47 AT2 receptor 5UNG LPA1 receptor 4Z35
TM1 43 1.48x48 AT2 receptor 5UNG D4 receptor 5WIV
TM1 44 1.49x49 AT2 receptor 5UNG κ receptor 6B73
TM1 45 1.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 46 1.51x51 AT2 receptor 5UNG κ receptor 6B73
TM1 47 1.52x52 AT2 receptor 5UNG PAR2 5NDD
TM1 48 1.53x53 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 49 1.54x54 AT2 receptor 5UNG US28 4XT1
TM1 50 1.55x55 AT2 receptor 5UNG A2A receptor 5G53
TM1 51 1.56x56 AT2 receptor 5UNG AT2 receptor 5UNG
TM1 52 1.57x57 AT2 receptor 5UNG CCR5 5UIW
TM1 53 1.58x58 AT2 receptor 5UNG CXCR4 3ODU
TM1 54 1.59x59 AT2 receptor 5UNG C5a1 receptor 5O9H
TM1 55 1.60x60 C5a1 receptor 5O9H US28 4XT1
ICL1 56 - - - -
ICL1 57 C5a1 receptor 5O9H - -
ICL1 58 - - - -
TM2 59 2.37x37 C5a1 receptor 5O9H LPA6 receptor 5XSZ
TM2 60 2.38x38 AT2 receptor 5UNG Rhodopsin 5DYS
TM2 61 2.39x39 AT2 receptor 5UNG P2Y12 receptor 4NTJ
TM2 62 2.40x40 AT2 receptor 5UNG - -
TM2 63 2.41x41 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 64 2.42x42 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 65 2.43x43 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 66 2.44x44 AT2 receptor 5UNG Rhodopsin 5DYS
TM2 67 2.45x45 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 68 2.46x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 69 2.47x47 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 70 2.48x48 AT2 receptor 5UNG US28 4XT1
TM2 71 2.49x49 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 72 2.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 73 2.51x51 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 74 2.52x52 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 75 2.53x53 AT2 receptor 5UNG US28 4XT1
TM2 76 2.54x54 AT2 receptor 5UNG AT2 receptor 5UNG
TM2 77 2.55x55 AT2 receptor 5UNG Rhodopsin 5DYS
TM2 78 2.56x56 AT2 receptor 5UNG M2 receptor 4MQT
TM2 79 2.57x57 AT2 receptor 5UNG κ receptor 6B73
TM2 80 2.58x58 AT2 receptor 5UNG - -
TM2 81 2.59x59 AT2 receptor 5UNG Rhodopsin 4ZWJ
TM2 82 2.60x60 AT2 receptor 5UNG Rhodopsin 4ZWJ
TM2 83 2.61x61 AT2 receptor 5UNG NTS1 receptor 5T04
TM2 84 2.62x62 AT2 receptor 5UNG PAR1 3VW7
TM2 85 2.63x63 AT2 receptor 5UNG S1P1 receptor 3V2Y
TM2 86 2.64x64 AT2 receptor 5UNG D2 receptor 6CM4
TM2 87 2.65x65 AT2 receptor 5UNG A2A receptor 5G53
TM2 88 2.66x66 AT2 receptor 5UNG C5a1 receptor 5O9H
ECL1 89 - - - -
ECL1 90 OX1 receptor 4ZJ8 - -
ECL1 91 OX1 receptor 4ZJ8 - -
ECL1 92 OX1 receptor 4ZJ8 - -
ECL1 93 - - - -
TM3 94 3.21x21 AT2 receptor 5UNG S1P1 receptor 3V2Y
TM3 95 3.22x22 AT2 receptor 5UNG κ receptor 6B73
TM3 96 3.23x23 AT2 receptor 5UNG - -
TM3 97 3.24x24 AT2 receptor 5UNG CB1 receptor 5XRA
TM3 98 3.25x25 AT2 receptor 5UNG - -
TM3 99 3.26x26 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM3 100 3.27x27 AT2 receptor 5UNG US28 4XT1
TM3 101 3.28x28 AT2 receptor 5UNG - -
TM3 102 3.29x29 AT2 receptor 5UNG - -
TM3 103 3.30x30 AT2 receptor 5UNG - -
TM3 104 3.31x31 AT2 receptor 5UNG NTS1 receptor 5T04
TM3 105 3.32x32 AT2 receptor 5UNG S1P1 receptor 3V2Y
TM3 106 3.33x33 AT2 receptor 5UNG κ receptor 6B73
TM3 107 3.34x34 AT2 receptor 5UNG AT1 receptor 4ZUD
TM3 108 3.35x35 AT2 receptor 5UNG US28 4XT1
TM3 109 3.36x36 AT2 receptor 5UNG CCR2 5T1A
TM3 110 3.37x37 AT2 receptor 5UNG CB1 receptor 5XRA
TM3 111 3.38x38 AT2 receptor 5UNG OX1 receptor 4ZJ8
TM3 112 3.39x39 AT2 receptor 5UNG CCR5 5UIW
TM3 113 3.40x40 AT2 receptor 5UNG US28 4XT1
TM3 114 3.41x41 AT2 receptor 5UNG P2Y12 receptor 4NTJ
TM3 115 3.42x42 AT2 receptor 5UNG C5a1 receptor 5O9H
TM3 116 3.43x43 AT2 receptor 5UNG κ receptor 6B73
TM3 117 3.44x44 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 118 3.45x45 AT2 receptor 5UNG A2A receptor 5G53
TM3 119 3.46x46 AT2 receptor 5UNG US28 4XT1
TM3 120 3.47x47 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 121 3.48x48 AT2 receptor 5UNG - -
TM3 122 3.49x49 AT2 receptor 5UNG PAR2 5NDD
TM3 123 3.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 124 3.51x51 AT2 receptor 5UNG - -
TM3 125 3.52x52 AT2 receptor 5UNG NTS1 receptor 5T04
TM3 126 3.53x53 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 127 3.54x54 AT2 receptor 5UNG AT2 receptor 5UNG
TM3 128 3.55x55 AT2 receptor 5UNG - -
TM3 129 3.56x56 AT2 receptor 5UNG FFA1 receptor 5TZY
ICL2 130 34.50x50 - - - -
ICL2 131 34.51x51 C5a1 receptor 5O9H C5a1 receptor 6C1R
ICL2 132 34.52x52 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 133 34.53x53 C5a1 receptor 5O9H - -
ICL2 134 34.54x54 C5a1 receptor 5O9H NTS1 receptor 5T04
ICL2 135 34.55x55 C5a1 receptor 5O9H - -
ICL2 136 34.56x56 C5a1 receptor 5O9H - -
ICL2 137 34.57x57 - - - -
TM4 138 4.38x38 C5a1 receptor 5O9H US28 4XT1
TM4 139 4.39x39 C5a1 receptor 5O9H NTS1 receptor 5T04
TM4 140 4.40x40 C5a1 receptor 5O9H - -
TM4 141 4.41x41 AT2 receptor 5UNG C5a1 receptor 5O9H
TM4 142 4.42x42 AT2 receptor 5UNG CCR9 5LWE
TM4 143 4.43x43 AT2 receptor 5UNG A1 receptor 6D9H
TM4 144 4.44x44 AT2 receptor 5UNG BLT1 receptor 5X33
TM4 145 4.45x45 AT2 receptor 5UNG μ receptor 5C1M
TM4 146 4.46x46 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM4 147 4.47x47 AT2 receptor 5UNG M3 receptor 4U15
TM4 148 4.48x48 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 149 4.49x49 AT2 receptor 5UNG apelin receptor 5VBL
TM4 150 4.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 151 4.51x51 AT2 receptor 5UNG CB1 receptor 5XRA
TM4 152 4.52x52 AT2 receptor 5UNG κ receptor 6B73
TM4 153 4.53x53 AT2 receptor 5UNG - -
TM4 154 4.54x54 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM4 155 4.55x55 AT2 receptor 5UNG AT2 receptor 5UNG
TM4 156 4.56x56 AT2 receptor 5UNG LPA1 receptor 4Z35
TM4 157 4.57x57 P2Y1 receptor 4XNW - -
TM4 158 4.58x58 P2Y1 receptor 4XNW S1P1 receptor 3V2Y
TM4 159 4.59x59 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
TM4 160 4.60x60 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM4 161 4.61x61 AT2 receptor 5UNG C5a1 receptor 5O9H
TM4 162 4.62x62 AT2 receptor 5UNG - -
TM4 163 4.63x63 AT2 receptor 5UNG NTS1 receptor 5T04
TM4 164 4.64x64 AT2 receptor 5UNG - -
ECL2 165 - - - -
ECL2 166 - - - -
ECL2 167 - - - -
ECL2 168 - - - -
ECL2 169 - - - -
ECL2 170 - - - -
ECL2 171 - - - -
ECL2 172 - - - -
TM5 173 5.31x32 AT2 receptor 5UNG - -
TM5 174 5.32x33 AT2 receptor 5UNG - -
TM5 175 5.33x34 AT2 receptor 5UNG - -
TM5 176 5.34x35 AT2 receptor 5UNG - -
TM5 177 5.35x36 AT2 receptor 5UNG Y1 receptor 5ZBH
TM5 178 5.36x37 AT2 receptor 5UNG CXCR4 3ODU
TM5 179 5.37x38 AT2 receptor 5UNG 5-HT2B receptor 5TUD
TM5 180 5.38x39 AT2 receptor 5UNG κ receptor 4DJH
TM5 181 5.39x40 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM5 182 5.40x41 AT2 receptor 5UNG NTS1 receptor 5T04
TM5 183 5.41x42 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM5 184 5.42x43 AT2 receptor 5UNG - -
TM5 185 5.43x44 AT2 receptor 5UNG C5a1 receptor 5O9H
TM5 186 5.44x45 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 187 5.45x46 AT2 receptor 5UNG NTS1 receptor 5T04
TM5 188 5.46x461 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 189 5.47x47 AT2 receptor 5UNG CB1 receptor 5XRA
TM5 190 5.48x48 AT2 receptor 5UNG NTS1 receptor 5T04
TM5 191 5.49x49 AT2 receptor 5UNG 5-HT2B receptor 5TUD
TM5 192 5.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM5 193 5.51x51 AT2 receptor 5UNG κ receptor 6B73
TM5 194 5.52x52 AT2 receptor 5UNG - -
TM5 195 5.53x53 AT2 receptor 5UNG C5a1 receptor 5O9H
TM5 196 5.54x54 AT2 receptor 5UNG 5-HT1B receptor 6G79
TM5 197 5.55x55 AT2 receptor 5UNG NTS1 receptor 5T04
TM5 198 5.56x56 AT2 receptor 5UNG PAR2 5NDD
TM5 199 5.57x57 AT2 receptor 5UNG NTS1 receptor 5T04
TM5 200 5.58x58 AT2 receptor 5UNG - -
TM5 201 5.59x59 AT2 receptor 5UNG A2A receptor 5G53
TM5 202 5.60x60 AT2 receptor 5UNG C5a1 receptor 5O9H
TM5 203 5.61x61 AT2 receptor 5UNG LPA6 receptor 5XSZ
TM5 204 5.62x62 AT2 receptor 5UNG AT1 receptor 4YAY
TM5 205 5.63x63 AT2 receptor 5UNG 5-HT1B receptor 6G79
TM5 206 5.64x64 AT2 receptor 5UNG κ receptor 6B73
TM5 207 5.65x65 AT2 receptor 5UNG - -
TM5 208 5.66x66 AT2 receptor 5UNG PAR1 3VW7
TM5 209 5.67x67 AT2 receptor 5UNG κ receptor 6B73
TM5 210 5.68x68 AT2 receptor 5UNG A2A receptor 5G53
ICL3 211 AT2 receptor 5UNG - -
ICL3 212 AT2 receptor 5UNG - -
ICL3 213 AT2 receptor 5UNG - -
TM6 214 6.28x28 AT2 receptor 5UNG μ receptor 6DDF
TM6 215 6.29x29 AT2 receptor 5UNG CXCR4 3ODU
TM6 216 6.30x30 AT2 receptor 5UNG - -
TM6 217 6.31x31 AT2 receptor 5UNG C5a1 receptor 6C1R
TM6 218 6.32x32 AT2 receptor 5UNG μ receptor 5C1M
TM6 219 6.33x33 AT2 receptor 5UNG CB1 receptor 5XRA
TM6 220 6.34x34 AT2 receptor 5UNG AT1 receptor 4ZUD
TM6 221 6.35x35 AT2 receptor 5UNG - -
TM6 222 6.36x36 AT2 receptor 5UNG NTS1 receptor 5T04
TM6 223 6.37x37 AT2 receptor 5UNG κ receptor 6B73
TM6 224 6.38x38 AT2 receptor 5UNG κ receptor 6B73
TM6 225 6.39x39 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 226 6.40x40 AT2 receptor 5UNG - -
TM6 227 6.41x41 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 228 6.42x42 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 229 6.43x43 AT2 receptor 5UNG κ receptor 6B73
TM6 230 6.44x44 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 231 6.45x45 AT2 receptor 5UNG Rhodopsin 5DYS
TM6 232 6.46x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 233 6.47x47 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 234 6.48x48 AT2 receptor 5UNG - -
TM6 235 6.49x49 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 236 6.50x50 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 237 6.51x51 AT2 receptor 5UNG CB1 receptor 5XRA
TM6 238 6.52x52 AT2 receptor 5UNG OX1 receptor 4ZJ8
TM6 239 6.53x53 AT2 receptor 5UNG κ receptor 6B73
TM6 240 6.54x54 AT2 receptor 5UNG μ receptor 5C1M
TM6 241 6.55x55 AT2 receptor 5UNG - -
TM6 242 6.56x56 AT2 receptor 5UNG AT2 receptor 5UNG
TM6 243 6.57x57 AT2 receptor 5UNG κ receptor 6B73
TM6 244 6.58x58 AT2 receptor 5UNG 5-HT2B receptor 5TUD
TM6 245 6.59x59 AT2 receptor 5UNG PAR2 5NDD
TM6 246 6.60x60 AT2 receptor 5UNG Y1 receptor 5ZBH
TM6 247 6.61x61 AT2 receptor 5UNG PAR2 5NDD
ECL3 248 - - - -
ECL3 249 A2A receptor 3VG9 - -
ECL3 250 A2A receptor 3VG9 - -
ECL3 251 A2A receptor 3VG9 - -
ECL3 252 A2A receptor 3VG9 - -
ECL3 253 - - - -
TM7 254 7.31x30 AT2 receptor 5UNG μ receptor 5C1M
TM7 255 7.32x31 AT2 receptor 5UNG NOP receptor 5DHG
TM7 256 7.33x32 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 257 7.34x33 AT2 receptor 5UNG OX1 receptor 4ZJ8
TM7 258 7.35x34 AT2 receptor 5UNG CB1 receptor 5XRA
TM7 259 7.36x35 AT2 receptor 5UNG C5a1 receptor 5O9H
TM7 260 7.37x36 AT2 receptor 5UNG NTS1 receptor 5T04
TM7 261 7.38x37 AT2 receptor 5UNG OX1 receptor 4ZJ8
TM7 262 7.39x38 AT2 receptor 5UNG P2Y1 receptor 4XNW
TM7 263 7.40x39 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 264 7.41x40 AT2 receptor 5UNG - -
TM7 265 7.42x41 AT2 receptor 5UNG A2A receptor 5G53
TM7 266 7.43x42 AT2 receptor 5UNG PAF receptor 5ZKP
TM7 267 7.44x43 AT2 receptor 5UNG β2-adrenoceptor 3SN6
TM7 268 7.45x45 AT2 receptor 5UNG NTS1 receptor 5T04
TM7 269 7.46x46 AT2 receptor 5UNG AT2 receptor 5UNG
TM7 270 7.47x47 AT2 receptor 5UNG κ receptor 6B73
TM7 271 7.48x48 AT2 receptor 5UNG OX1 receptor 4ZJ8
TM7 272 7.49x49 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 273 7.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 274 7.51x51 C5a1 receptor 5O9H μ receptor 6DDF
TM7 275 7.52x52 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 276 7.53x53 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 277 7.54x54 C5a1 receptor 5O9H P2Y1 receptor 4XNW
TM7 278 7.55x55 C5a1 receptor 5O9H M2 receptor 4MQT
TM7 279 7.56x56 C5a1 receptor 5O9H AT2 receptor 5UNG
H8 280 8.47x47 OX1 receptor 4ZJ8 AT2 receptor 5UNG
H8 281 8.48x48 OX1 receptor 4ZJ8 - -
H8 282 8.49x49 OX1 receptor 4ZJ8 AT2 receptor 5UNG
H8 283 8.50x50 OX1 receptor 4ZJ8 - -
H8 284 8.51x51 OX1 receptor 4ZJ8 LPA1 receptor 4Z35
H8 285 8.52x52 OX1 receptor 4ZJ8 CB1 receptor 5XRA
H8 286 8.53x53 OX1 receptor 4ZJ8 - -
H8 287 8.54x54 OX1 receptor 4ZJ8 AT2 receptor 5UNG
H8 288 8.55x55 OX1 receptor 4ZJ8 - -
H8 289 8.56x56 OX1 receptor 4ZJ8 Rhodopsin 5DYS
C-term 290 - - - -
C-term 291 - - - -
C-term 292 - - - -
C-term 293 - - - -
C-term 294 - - - -