MRGPRF homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): -1.42 docs)

VERSION

2018-07-10

MAIN TEMPLATE

C5a1 receptor (sequence similarity: 40%) PDB: 5O9H

TEMPLATES

Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 86.1 5.8 8.0
Side-chains 22.3 49.6 28.1

Number of backbone templates: 4
Number of rotamer templates: 38

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5O9H
4XNW
5TZY
4DJH
None

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 36 - - - -
N-term 37 - - - -
N-term 38 C5a1 receptor 5O9H C5a1 receptor 5O9H
N-term 39 C5a1 receptor 5O9H C5a1 receptor 5O9H
N-term 40 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 41 1.29x29 C5a1 receptor 5O9H - -
TM1 42 1.30x30 C5a1 receptor 5O9H 5-HT1B receptor 4IAQ
TM1 43 1.31x31 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 44 1.32x32 C5a1 receptor 5O9H κ receptor 4DJH
TM1 45 1.33x33 C5a1 receptor 5O9H A1 receptor 5UEN
TM1 46 1.34x34 C5a1 receptor 5O9H A2A receptor 3VG9
TM1 47 1.35x35 C5a1 receptor 5O9H β2-adrenoceptor 5JQH
TM1 48 1.36x36 C5a1 receptor 5O9H - -
TM1 49 1.37x37 C5a1 receptor 5O9H - -
TM1 50 1.38x38 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 51 1.39x39 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 52 1.40x40 C5a1 receptor 5O9H A2A receptor 3VG9
TM1 53 1.41x41 C5a1 receptor 5O9H A1 receptor 5UEN
TM1 54 1.42x42 C5a1 receptor 5O9H M4 receptor 5DSG
TM1 55 1.43x43 C5a1 receptor 5O9H μ receptor 4DKL
TM1 56 1.44x44 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 57 1.45x45 C5a1 receptor 5O9H - -
TM1 58 1.46x46 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 59 1.47x47 C5a1 receptor 5O9H κ receptor 4DJH
TM1 60 1.48x48 C5a1 receptor 5O9H κ receptor 4DJH
TM1 61 1.49x49 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 62 1.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 63 1.51x51 C5a1 receptor 5O9H CXCR4 3ODU
TM1 64 1.52x52 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 65 1.53x53 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 66 1.54x54 C5a1 receptor 5O9H apelin receptor 5VBL
TM1 67 1.55x55 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 68 1.56x56 C5a1 receptor 5O9H - -
TM1 69 1.57x57 C5a1 receptor 5O9H M1 receptor 5CXV
TM1 70 1.58x58 C5a1 receptor 5O9H CXCR4 3ODU
TM1 71 1.59x59 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM1 72 1.60x60 C5a1 receptor 5O9H apelin receptor 5VBL
ICL1 73 C5a1 receptor 5O9H - -
ICL1 74 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL1 75 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 76 2.37x37 C5a1 receptor 5O9H A2A receptor 3VG9
TM2 77 2.38x38 C5a1 receptor 5O9H S1P1 receptor 3V2Y
TM2 78 2.39x39 C5a1 receptor 5O9H P2Y12 receptor 4NTJ
TM2 79 2.40x40 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM2 80 2.41x41 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 81 2.42x42 C5a1 receptor 5O9H κ receptor 4DJH
TM2 82 2.43x43 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 83 2.44x44 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 84 2.45x45 C5a1 receptor 5O9H CXCR4 3ODU
TM2 85 2.46x46 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 86 2.47x47 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 87 2.48x48 C5a1 receptor 5O9H - -
TM2 88 2.49x49 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 89 2.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM2 90 2.51x51 C5a1 receptor 5O9H A1 receptor 5UEN
TM2 91 2.52x52 C5a1 receptor 5O9H - -
TM2 92 2.53x53 C5a1 receptor 5O9H P2Y1 receptor 4XNW
TM2 93 2.54x54 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM2 94 2.55x55 C5a1 receptor 5O9H Rhodopsin 1GZM
TM2 95 2.56x56 C5a1 receptor 5O9H M4 receptor 5DSG
TM2 96 2.57x57 C5a1 receptor 5O9H - -
TM2 97 2.58x58 C5a1 receptor 5O9H - -
TM2 98 2.59x59 C5a1 receptor 5O9H NTS1 receptor 4BUO
TM2 99 2.60x60 C5a1 receptor 5O9H M3 receptor 4U15
TM2 100 2.61x61 C5a1 receptor 5O9H κ receptor 4DJH
TM2 101 2.62x62 C5a1 receptor 5O9H CCR9 5LWE
TM2 102 2.63x63 C5a1 receptor 5O9H S1P1 receptor 3V2Y
TM2 103 2.64x64 C5a1 receptor 5O9H A1 receptor 5UEN
TM2 104 2.65x65 C5a1 receptor 5O9H A2A receptor 3VG9
TM2 105 2.66x66 C5a1 receptor 5O9H A1 receptor 5N2S
TM2 106 2.67x67 C5a1 receptor 5O9H D2 receptor 6CM4
ECL1 107 C5a1 receptor 5O9H - -
ECL1 108 C5a1 receptor 5O9H - -
ECL1 109 C5a1 receptor 5O9H - -
ECL1 110 C5a1 receptor 5O9H - -
ECL1 111 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM3 112 3.21x21 C5a1 receptor 5O9H A2A receptor 3VG9
TM3 113 3.22x22 C5a1 receptor 5O9H κ receptor 4DJH
TM3 114 3.23x23 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM3 115 3.24x24 C5a1 receptor 5O9H - -
TM3 116 3.25x25 C5a1 receptor 5O9H - -
TM3 117 3.26x26 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM3 118 3.27x27 C5a1 receptor 5O9H CCR9 5LWE
TM3 119 3.28x28 C5a1 receptor 5O9H BLT1 receptor 5X33
TM3 120 3.29x29 C5a1 receptor 5O9H P2Y1 receptor 4XNW
TM3 121 3.30x30 C5a1 receptor 5O9H CXCR4 3ODU
TM3 122 3.31x31 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM3 123 3.32x32 C5a1 receptor 5O9H - -
TM3 124 3.33x33 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM3 125 3.34x34 C5a1 receptor 5O9H PAR1 3VW7
TM3 126 3.35x35 C5a1 receptor 5O9H D2 receptor 6CM4
TM3 127 3.36x36 C5a1 receptor 5O9H CCR5 5UIW
TM3 128 3.37x37 C5a1 receptor 5O9H - -
TM3 129 3.38x38 C5a1 receptor 5O9H κ receptor 4DJH
TM3 130 3.39x39 C5a1 receptor 5O9H CCR5 5UIW
TM3 131 3.40x40 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM3 132 3.41x41 C5a1 receptor 5O9H P2Y12 receptor 4NTJ
TM3 133 3.42x42 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM3 134 3.43x43 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM3 135 3.44x44 C5a1 receptor 5O9H - -
TM3 136 3.45x45 C5a1 receptor 5O9H A1 receptor 5UEN
TM3 137 3.46x46 C5a1 receptor 5O9H - -
TM3 138 3.47x47 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM3 139 3.48x48 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM3 140 3.49x49 C5a1 receptor 5O9H S1P1 receptor 3V2Y
TM3 141 3.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM3 142 3.51x51 C5a1 receptor 5O9H - -
TM3 143 3.52x52 C5a1 receptor 5O9H - -
TM3 144 3.53x53 C5a1 receptor 5O9H M1 receptor 5CXV
TM3 145 3.54x54 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM3 146 3.55x55 C5a1 receptor 5O9H Y1 receptor 5ZBH
TM3 147 3.56x56 C5a1 receptor 5O9H FFA1 receptor 5TZY
ICL2 148 34.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 149 34.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 150 34.52x52 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 151 34.53x53 C5a1 receptor 5O9H A1 receptor 5UEN
ICL2 152 34.54x54 C5a1 receptor 5O9H - -
ICL2 153 34.55x55 C5a1 receptor 5O9H C5a1 receptor 5O9H
ICL2 154 34.56x56 C5a1 receptor 5O9H P2Y1 receptor 4XNW
ICL2 155 34.57x57 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 156 4.38x38 C5a1 receptor 5O9H US28 4XT1
TM4 157 4.39x39 C5a1 receptor 5O9H β2-adrenoceptor 2RH1
TM4 158 4.40x40 C5a1 receptor 5O9H μ receptor 4DKL
TM4 159 4.41x41 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 160 4.42x42 C5a1 receptor 5O9H CCR9 5LWE
TM4 161 4.43x43 C5a1 receptor 5O9H A1 receptor 5UEN
TM4 162 4.44x44 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM4 163 4.45x45 C5a1 receptor 5O9H μ receptor 4DKL
TM4 164 4.46x46 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 165 4.47x47 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 166 4.48x48 C5a1 receptor 5O9H M1 receptor 5CXV
TM4 167 4.49x49 C5a1 receptor 5O9H apelin receptor 5VBL
TM4 168 4.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 169 4.51x51 C5a1 receptor 5O9H δ receptor 4N6H
TM4 170 4.52x52 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 171 4.53x53 C5a1 receptor 5O9H κ receptor 4DJH
TM4 172 4.54x54 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 173 4.55x55 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM4 174 4.56x56 C5a1 receptor 5O9H κ receptor 4DJH
TM4 175 4.57x57 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
TM4 176 4.58x58 P2Y1 receptor 4XNW - -
TM4 177 4.59x59 P2Y1 receptor 4XNW AT1 receptor 4ZUD
TM4 178 4.60x60 C5a1 receptor 5O9H - -
TM4 179 4.61x61 C5a1 receptor 5O9H CCR5 5UIW
TM4 180 4.62x62 C5a1 receptor 5O9H PAR2 5NDD
TM4 181 4.63x63 C5a1 receptor 5O9H M4 receptor 5DSG
TM4 182 4.64x64 C5a1 receptor 5O9H - -
ECL2 183 - - - -
ECL2 184 - - - -
ECL2 185 - - - -
ECL2 186 - - - -
ECL2 187 - - - -
ECL2 188 - - - -
ECL2 189 - - - -
ECL2 190 - - - -
ECL2 191 - - - -
TM5 192 5.31x32 C5a1 receptor 5O9H - -
TM5 193 5.32x33 C5a1 receptor 5O9H AT2 receptor 5UNG
TM5 194 5.33x34 C5a1 receptor 5O9H - -
TM5 195 5.34x35 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM5 196 5.35x36 C5a1 receptor 5O9H P2Y12 receptor 4NTJ
TM5 197 5.36x37 C5a1 receptor 5O9H A1 receptor 5UEN
TM5 198 5.37x38 C5a1 receptor 5O9H D3 receptor 3PBL
TM5 199 5.38x39 C5a1 receptor 5O9H M1 receptor 5CXV
TM5 200 5.39x40 C5a1 receptor 5O9H PAR2 5NDD
TM5 201 5.40x41 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM5 202 5.41x42 C5a1 receptor 5O9H M4 receptor 5DSG
TM5 203 5.42x43 C5a1 receptor 5O9H CCR5 5UIW
TM5 204 5.43x44 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM5 205 5.44x45 C5a1 receptor 5O9H δ receptor 4N6H
TM5 206 5.45x46 C5a1 receptor 5O9H κ receptor 4DJH
TM5 207 5.46x461 C5a1 receptor 5O9H FFA1 receptor 5TZY
TM5 208 5.47x47 C5a1 receptor 5O9H CXCR4 3ODU
TM5 209 5.48x48 C5a1 receptor 5O9H ETB receptor 5X93
TM5 210 5.49x49 C5a1 receptor 5O9H - -
TM5 211 5.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM5 212 5.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM5 213 5.52x52 C5a1 receptor 5O9H - -
TM5 214 5.53x53 C5a1 receptor 5O9H CXCR4 3ODU
TM5 215 5.54x54 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM5 216 5.55x55 C5a1 receptor 5O9H - -
TM5 217 5.56x56 C5a1 receptor 5O9H - -
TM5 218 5.57x57 C5a1 receptor 5O9H M4 receptor 5DSG
TM5 219 5.58x58 C5a1 receptor 5O9H - -
TM5 220 5.59x59 C5a1 receptor 5O9H A1 receptor 5UEN
TM5 221 5.60x60 C5a1 receptor 5O9H CXCR4 3ODU
TM5 222 5.61x61 C5a1 receptor 5O9H Rhodopsin 1GZM
TM5 223 5.62x62 C5a1 receptor 5O9H - -
TM5 224 5.63x63 C5a1 receptor 5O9H D3 receptor 3PBL
TM5 225 5.64x64 C5a1 receptor 5O9H M3 receptor 4U15
TM5 226 5.65x65 C5a1 receptor 5O9H - -
TM5 227 5.66x66 C5a1 receptor 5O9H A1 receptor 5UEN
TM5 228 5.67x67 C5a1 receptor 5O9H - -
TM5 229 5.68x68 C5a1 receptor 5O9H C5a1 receptor 6C1R
ICL3 230 - - - -
ICL3 231 - - - -
ICL3 232 - - - -
ICL3 233 - - - -
TM6 234 6.30x30 P2Y1 receptor 4XNW C5a1 receptor 6C1R
TM6 235 6.31x31 C5a1 receptor 5O9H - -
TM6 236 6.32x32 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM6 237 6.33x33 C5a1 receptor 5O9H apelin receptor 5VBL
TM6 238 6.34x34 C5a1 receptor 5O9H Y1 receptor 5ZBH
TM6 239 6.35x35 C5a1 receptor 5O9H - -
TM6 240 6.36x36 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM6 241 6.37x37 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM6 242 6.38x38 C5a1 receptor 5O9H κ receptor 4DJH
TM6 243 6.39x39 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM6 244 6.40x40 C5a1 receptor 5O9H Rhodopsin 1GZM
TM6 245 6.41x41 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM6 246 6.42x42 C5a1 receptor 5O9H S1P1 receptor 3V2Y
TM6 247 6.43x43 C5a1 receptor 5O9H κ receptor 4DJH
TM6 248 6.44x44 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM6 249 6.45x45 C5a1 receptor 5O9H 5-HT2C receptor 6BQH
TM6 250 6.46x46 C5a1 receptor 5O9H κ receptor 4DJH
TM6 251 6.47x47 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM6 252 6.48x48 C5a1 receptor 5O9H - -
TM6 253 6.49x49 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM6 254 6.50x50 C5a1 receptor 5O9H - -
TM6 255 6.51x51 C5a1 receptor 5O9H A1 receptor 5UEN
TM6 256 6.52x52 C5a1 receptor 5O9H - -
TM6 257 6.53x53 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM6 258 6.54x54 C5a1 receptor 5O9H - -
TM6 259 6.55x55 C5a1 receptor 5O9H - -
TM6 260 6.56x56 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM6 261 6.57x57 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM6 262 6.58x58 C5a1 receptor 5O9H Y1 receptor 5ZBH
TM6 263 6.59x59 C5a1 receptor 5O9H - -
TM6 264 6.60x60 C5a1 receptor 5O9H OX2 receptor 5WS3
TM6 265 6.61x61 C5a1 receptor 5O9H OX1 receptor 4ZJ8
ECL3 266 - - - -
ECL3 267 FFA1 receptor 5TZY - -
ECL3 268 FFA1 receptor 5TZY - -
ECL3 269 - - - -
TM7 270 7.32x31 C5a1 receptor 5O9H D2 receptor 6CM4
TM7 271 7.33x32 C5a1 receptor 5O9H S1P1 receptor 3V2Y
TM7 272 7.34x33 C5a1 receptor 5O9H - -
TM7 273 7.35x34 C5a1 receptor 5O9H LPA1 receptor 4Z35
TM7 274 7.36x35 C5a1 receptor 5O9H κ receptor 4DJH
TM7 275 7.37x36 C5a1 receptor 5O9H CCR5 5UIW
TM7 276 7.38x37 C5a1 receptor 5O9H AT1 receptor 4ZUD
TM7 277 7.39x38 C5a1 receptor 5O9H - -
TM7 278 7.40x39 C5a1 receptor 5O9H Y1 receptor 5ZBH
TM7 279 7.41x40 C5a1 receptor 5O9H - -
TM7 280 7.42x41 C5a1 receptor 5O9H - -
TM7 281 7.43x42 C5a1 receptor 5O9H - -
TM7 282 7.44x43 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 283 7.45x45 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 284 7.46x46 C5a1 receptor 5O9H κ receptor 4DJH
TM7 285 7.47x47 C5a1 receptor 5O9H κ receptor 4DJH
TM7 286 7.48x48 C5a1 receptor 5O9H OX2 receptor 5WS3
TM7 287 7.49x49 C5a1 receptor 5O9H - -
TM7 288 7.50x50 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 289 7.51x51 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 290 7.52x52 C5a1 receptor 5O9H A1 receptor 5UEN
TM7 291 7.53x53 C5a1 receptor 5O9H C5a1 receptor 5O9H
TM7 292 7.54x54 C5a1 receptor 5O9H P2Y1 receptor 4XNW
TM7 293 7.55x55 C5a1 receptor 5O9H M4 receptor 5DSG
TM7 294 7.56x56 C5a1 receptor 5O9H C5a1 receptor 5O9H
H8 295 8.47x47 κ receptor 4DJH CCR5 5UIW
H8 296 8.48x48 κ receptor 4DJH A2A receptor 3VG9
H8 297 8.49x49 κ receptor 4DJH β2-adrenoceptor 5JQH
H8 298 8.50x50 κ receptor 4DJH - -
H8 299 8.51x51 κ receptor 4DJH LPA1 receptor 4Z35
H8 300 8.52x52 κ receptor 4DJH apelin receptor 5VBL
H8 301 8.53x53 κ receptor 4DJH - -
H8 302 8.54x54 κ receptor 4DJH CCR5 5UIW
H8 303 8.55x55 κ receptor 4DJH - -
H8 304 8.56x56 κ receptor 4DJH β2-adrenoceptor 2RH1
C-term 305 - - - -
C-term 306 - - - -
C-term 307 - - - -
C-term 308 - - - -
C-term 309 - - - -