HEADER RECEPTOR 23-MAR-11 2YDO TITLE THERMOSTABILISED HUMAN A2A RECEPTOR WITH ADENOSINE BOUND COMPND MOL_ID: 1; COMPND 2 MOLECULE: ADENOSINE RECEPTOR A2A; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: RESIDUES 1-317; COMPND 5 SYNONYM: THERMOSTABILISED HUMAN A2A RECEPTOR; COMPND 6 ENGINEERED: YES; COMPND 7 MUTATION: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 TISSUE: BRAIN; SOURCE 6 EXPRESSION_SYSTEM: TRICHOPLUSIA NI; SOURCE 7 EXPRESSION_SYSTEM_COMMON: CABBAGE LOOPER; SOURCE 8 EXPRESSION_SYSTEM_TAXID: 7111; SOURCE 9 EXPRESSION_SYSTEM_CELL_LINE: HIGH FIVE; SOURCE 10 EXPRESSION_SYSTEM_VECTOR_TYPE: BACULOVIRUS; SOURCE 11 EXPRESSION_SYSTEM_PLASMID: PBACPAK8 KEYWDS RECEPTOR, G PROTEIN COUPLED RECEPTOR, SEVEN-HELIX RECEPTOR, AGONIST KEYWDS 2 BOUND FORM, THERMOSTABILISING POINT MUTATIONS, GPCR, 7TM RECEPTOR EXPDTA X-RAY DIFFRACTION AUTHOR G.LEBON,T.WARNE,P.C.EDWARDS,K.BENNETT,C.J.LANGMEAD,A.G.W.LESLIE, AUTHOR 2 C.G.TATE REVDAT 5 29-JUL-20 2YDO 1 COMPND REMARK HETNAM SITE REVDAT 4 03-APR-19 2YDO 1 SOURCE REVDAT 3 22-JUN-11 2YDO 1 JRNL REVDAT 2 01-JUN-11 2YDO 1 REMARK MASTER REVDAT 1 18-MAY-11 2YDO 0 JRNL AUTH G.LEBON,T.WARNE,P.C.EDWARDS,K.BENNETT,C.J.LANGMEAD, JRNL AUTH 2 A.G.W.LESLIE,C.G.TATE JRNL TITL AGONIST-BOUND ADENOSINE A(2A) RECEPTOR STRUCTURES REVEAL JRNL TITL 2 COMMON FEATURES OF GPCR ACTIVATION. JRNL REF NATURE V. 474 521 2011 JRNL REFN ISSN 0028-0836 JRNL PMID 21593763 JRNL DOI 10.1038/NATURE10136 REMARK 1 REMARK 1 REFERENCE 1 REMARK 1 AUTH G.LEBON,K.BENNETT,A.JAZAYERI,C.G.TATE REMARK 1 TITL THERMOSTABILISATION OF AN AGONIST-BOUND CONFORMATION OF THE REMARK 1 TITL 2 HUMAN ADENOSINE A(2A) RECEPTOR. REMARK 1 REF J.MOL.BIOL. V. 409 298 2011 REMARK 1 REFN ISSN 0022-2836 REMARK 1 PMID 21501622 REMARK 1 DOI 10.1016/J.JMB.2011.03.075 REMARK 2 REMARK 2 RESOLUTION. 3.00 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.6.0100 REMARK 3 AUTHORS : MURSHUDOV,SKUBAK,LEBEDEV,PANNU,STEINER, REMARK 3 : NICHOLLS,WINN,LONG,VAGIN REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 3.00 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 60.42 REMARK 3 DATA CUTOFF (SIGMA(F)) : NULL REMARK 3 COMPLETENESS FOR RANGE (%) : 93.5 REMARK 3 NUMBER OF REFLECTIONS : 10556 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.246 REMARK 3 R VALUE (WORKING SET) : 0.244 REMARK 3 FREE R VALUE : 0.269 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.200 REMARK 3 FREE R VALUE TEST SET COUNT : 575 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 3.00 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 3.08 REMARK 3 REFLECTION IN BIN (WORKING SET) : 745 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 91.87 REMARK 3 BIN R VALUE (WORKING SET) : 0.3360 REMARK 3 BIN FREE R VALUE SET COUNT : 35 REMARK 3 BIN FREE R VALUE : 0.2600 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 2410 REMARK 3 NUCLEIC ACID ATOMS : 0 REMARK 3 HETEROGEN ATOMS : 59 REMARK 3 SOLVENT ATOMS : 18 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 95.60 REMARK 3 MEAN B VALUE (OVERALL, A**2) : 92.99 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : -2.05000 REMARK 3 B22 (A**2) : 0.88000 REMARK 3 B33 (A**2) : 1.09000 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : -0.64000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 1.532 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.408 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.333 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 18.034 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.903 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.913 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 2533 ; 0.006 ; 0.022 REMARK 3 BOND LENGTHS OTHERS (A): 65 ; 0.001 ; 0.020 REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 3452 ; 0.983 ; 1.970 REMARK 3 BOND ANGLES OTHERS (DEGREES): 147 ; 0.529 ; 3.000 REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 307 ; 4.135 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 95 ;36.421 ;22.526 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 393 ;15.786 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 13 ; 9.811 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 413 ; 0.065 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 1835 ; 0.003 ; 0.021 REMARK 3 GENERAL PLANES OTHERS (A): 6 ; 0.001 ; 0.020 REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.20 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING REMARK 3 POSITIONS. HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT. U REMARK 3 VALUES REFINED INDIVIDUALLY REMARK 4 REMARK 4 2YDO COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 23-MAR-11. REMARK 100 THE DEPOSITION ID IS D_1290047787. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 09-DEC-10 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 7.6 REMARK 200 NUMBER OF CRYSTALS USED : 2 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : DIAMOND REMARK 200 BEAMLINE : I24 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.9778 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : PIXEL REMARK 200 DETECTOR MANUFACTURER : DECTRIS PILATUS 6M REMARK 200 INTENSITY-INTEGRATION SOFTWARE : MOSFLM REMARK 200 DATA SCALING SOFTWARE : SCALA REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 10556 REMARK 200 RESOLUTION RANGE HIGH (A) : 3.000 REMARK 200 RESOLUTION RANGE LOW (A) : 79.340 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : 0.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 93.9 REMARK 200 DATA REDUNDANCY : 2.600 REMARK 200 R MERGE (I) : 0.10000 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 7.1000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 3.00 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 3.16 REMARK 200 COMPLETENESS FOR SHELL (%) : 95.0 REMARK 200 DATA REDUNDANCY IN SHELL : 2.40 REMARK 200 R MERGE FOR SHELL (I) : 0.55000 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 2.200 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: PDB ENTRY 3EML REMARK 200 REMARK 200 REMARK: NONE REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 68.90 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.95 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 0.05 M TRISHCL, PH 7.6, 9.6% PEG 200, REMARK 280 22.9%. PEG 300 REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 1 2 1 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,Y,-Z REMARK 290 3555 X+1/2,Y+1/2,Z REMARK 290 4555 -X+1/2,Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 3 1.000000 0.000000 0.000000 38.23250 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 49.43450 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 38.23250 REMARK 290 SMTRY2 4 0.000000 1.000000 0.000000 49.43450 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: MONOMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: MONOMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 APPLY THE FOLLOWING TO CHAINS: A REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 400 REMARK 400 COMPOUND REMARK 400 ENGINEERED RESIDUE IN CHAIN A, LEU 48 TO ALA REMARK 400 ENGINEERED RESIDUE IN CHAIN A, ALA 54 TO LEU REMARK 400 ENGINEERED RESIDUE IN CHAIN A, THR 65 TO ALA REMARK 400 ENGINEERED RESIDUE IN CHAIN A, GLN 89 TO ALA REMARK 400 ENGINEERED RESIDUE IN CHAIN A, ASN 154 TO ALA REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A 1 REMARK 465 PRO A 2 REMARK 465 ILE A 3 REMARK 465 MET A 4 REMARK 465 GLY A 5 REMARK 465 GLN A 214 REMARK 465 PRO A 215 REMARK 465 LEU A 216 REMARK 465 PRO A 217 REMARK 465 GLY A 218 REMARK 465 GLU A 219 REMARK 465 ARG A 220 REMARK 465 ALA A 221 REMARK 465 ARG A 222 REMARK 465 SER A 223 REMARK 465 GLN A 325 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 CYS A 166 89.13 -69.74 REMARK 500 REMARK 500 REMARK: NULL REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 1UPE RELATED DB: PDB REMARK 900 MODELING THE ADENOSINE RECEPTORS: COMPARISON OF THE BINDING DOMAINS REMARK 900 OF A2A AGONISTS AND ANTAGONISTS REMARK 900 RELATED ID: 1MMH RELATED DB: PDB REMARK 900 MOLECULAR MODEL OF THE HUMAN A2A ADENOSINE RECEPTOR REMARK 900 RELATED ID: 2YDV RELATED DB: PDB REMARK 900 THERMOSTABILISED HUMAN A2A RECEPTOR WITH NECA BOUND REMARK 999 REMARK 999 SEQUENCE REMARK 999 THE CONSTRUCT WAS TRUNCATED AFTER RESIDUE 316 OF THE A2A REMARK 999 SEQUENCE. CONSTRUCT CRYSTALLISED CONTAINS THERMOSTABILISING REMARK 999 MUTATIONS L48A, A54L, T65A, Q89A. REMOVAL OF GLYCOSYLATION REMARK 999 SITE BY MUTATION N154A. AT C-TERMINUS, THERE IS A LINKER REMARK 999 PLUS TEV CLEAVAGE SEQUENCE AAAENLYFQ. DBREF 2YDO A 1 317 UNP P29274 AA2AR_HUMAN 1 317 SEQADV 2YDO ALA A 48 UNP P29274 LEU 48 ENGINEERED MUTATION SEQADV 2YDO LEU A 54 UNP P29274 ALA 54 ENGINEERED MUTATION SEQADV 2YDO ALA A 65 UNP P29274 THR 65 ENGINEERED MUTATION SEQADV 2YDO ALA A 89 UNP P29274 GLN 89 ENGINEERED MUTATION SEQADV 2YDO ALA A 154 UNP P29274 ASN 154 ENGINEERED MUTATION SEQADV 2YDO ALA A 318 UNP P29274 EXPRESSION TAG SEQADV 2YDO ALA A 319 UNP P29274 EXPRESSION TAG SEQADV 2YDO GLU A 320 UNP P29274 EXPRESSION TAG SEQADV 2YDO ASN A 321 UNP P29274 EXPRESSION TAG SEQADV 2YDO LEU A 322 UNP P29274 EXPRESSION TAG SEQADV 2YDO TYR A 323 UNP P29274 EXPRESSION TAG SEQADV 2YDO PHE A 324 UNP P29274 EXPRESSION TAG SEQADV 2YDO GLN A 325 UNP P29274 EXPRESSION TAG SEQRES 1 A 325 MET PRO ILE MET GLY SER SER VAL TYR ILE THR VAL GLU SEQRES 2 A 325 LEU ALA ILE ALA VAL LEU ALA ILE LEU GLY ASN VAL LEU SEQRES 3 A 325 VAL CYS TRP ALA VAL TRP LEU ASN SER ASN LEU GLN ASN SEQRES 4 A 325 VAL THR ASN TYR PHE VAL VAL SER ALA ALA ALA ALA ASP SEQRES 5 A 325 ILE LEU VAL GLY VAL LEU ALA ILE PRO PHE ALA ILE ALA SEQRES 6 A 325 ILE SER THR GLY PHE CYS ALA ALA CYS HIS GLY CYS LEU SEQRES 7 A 325 PHE ILE ALA CYS PHE VAL LEU VAL LEU THR ALA SER SER SEQRES 8 A 325 ILE PHE SER LEU LEU ALA ILE ALA ILE ASP ARG TYR ILE SEQRES 9 A 325 ALA ILE ARG ILE PRO LEU ARG TYR ASN GLY LEU VAL THR SEQRES 10 A 325 GLY THR ARG ALA LYS GLY ILE ILE ALA ILE CYS TRP VAL SEQRES 11 A 325 LEU SER PHE ALA ILE GLY LEU THR PRO MET LEU GLY TRP SEQRES 12 A 325 ASN ASN CYS GLY GLN PRO LYS GLU GLY LYS ALA HIS SER SEQRES 13 A 325 GLN GLY CYS GLY GLU GLY GLN VAL ALA CYS LEU PHE GLU SEQRES 14 A 325 ASP VAL VAL PRO MET ASN TYR MET VAL TYR PHE ASN PHE SEQRES 15 A 325 PHE ALA CYS VAL LEU VAL PRO LEU LEU LEU MET LEU GLY SEQRES 16 A 325 VAL TYR LEU ARG ILE PHE LEU ALA ALA ARG ARG GLN LEU SEQRES 17 A 325 LYS GLN MET GLU SER GLN PRO LEU PRO GLY GLU ARG ALA SEQRES 18 A 325 ARG SER THR LEU GLN LYS GLU VAL HIS ALA ALA LYS SER SEQRES 19 A 325 LEU ALA ILE ILE VAL GLY LEU PHE ALA LEU CYS TRP LEU SEQRES 20 A 325 PRO LEU HIS ILE ILE ASN CYS PHE THR PHE PHE CYS PRO SEQRES 21 A 325 ASP CYS SER HIS ALA PRO LEU TRP LEU MET TYR LEU ALA SEQRES 22 A 325 ILE VAL LEU SER HIS THR ASN SER VAL VAL ASN PRO PHE SEQRES 23 A 325 ILE TYR ALA TYR ARG ILE ARG GLU PHE ARG GLN THR PHE SEQRES 24 A 325 ARG LYS ILE ILE ARG SER HIS VAL LEU ARG GLN GLN GLU SEQRES 25 A 325 PRO PHE LYS ALA ALA ALA ALA GLU ASN LEU TYR PHE GLN HET ADN A 400 19 HET SOG A 501 20 HET SOG A 502 20 HETNAM ADN ADENOSINE HETNAM SOG OCTYL 1-THIO-BETA-D-GLUCOPYRANOSIDE HETSYN SOG 1-S-OCTYL-BETA-D-THIOGLUCOSIDE FORMUL 2 ADN C10 H13 N5 O4 FORMUL 3 SOG 2(C14 H28 O5 S) FORMUL 5 HOH *18(H2 O) HELIX 1 1 SER A 6 ASN A 34 1 29 HELIX 2 2 SER A 35 GLN A 38 5 4 HELIX 3 3 ASN A 39 LEU A 58 1 20 HELIX 4 4 LEU A 58 ILE A 66 1 9 HELIX 5 5 ALA A 73 ILE A 108 1 36 HELIX 6 6 ARG A 111 VAL A 116 1 6 HELIX 7 7 THR A 117 LEU A 137 1 21 HELIX 8 8 THR A 138 GLY A 142 5 5 HELIX 9 9 ASN A 144 GLN A 148 5 5 HELIX 10 10 LYS A 150 GLN A 157 1 8 HELIX 11 11 LEU A 167 VAL A 172 1 6 HELIX 12 12 PRO A 173 PHE A 180 1 8 HELIX 13 13 PHE A 180 VAL A 186 1 7 HELIX 14 14 VAL A 186 MET A 211 1 26 HELIX 15 15 THR A 224 CYS A 259 1 36 HELIX 16 16 PRO A 266 THR A 279 1 14 HELIX 17 17 THR A 279 ASN A 284 1 6 HELIX 18 18 PRO A 285 ARG A 291 1 7 HELIX 19 19 ILE A 292 GLN A 311 1 20 HELIX 20 20 GLN A 311 PHE A 324 1 14 SHEET 1 AA 2 CYS A 71 ALA A 72 0 SHEET 2 AA 2 VAL A 164 ALA A 165 -1 O VAL A 164 N ALA A 72 SSBOND 1 CYS A 71 CYS A 159 1555 1555 2.04 SSBOND 2 CYS A 74 CYS A 146 1555 1555 2.05 SSBOND 3 CYS A 77 CYS A 166 1555 1555 2.04 SSBOND 4 CYS A 259 CYS A 262 1555 1555 2.03 CISPEP 1 ASN A 284 PRO A 285 0 -0.50 CRYST1 76.465 98.869 79.516 90.00 93.49 90.00 C 1 2 1 4 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.013078 0.000000 0.000798 0.00000 SCALE2 0.000000 0.010114 0.000000 0.00000 SCALE3 0.000000 0.000000 0.012599 0.00000 ATOM 1 N SER A 6 -28.148 4.590 -7.800 1.00113.33 N ATOM 2 CA SER A 6 -26.785 4.701 -7.207 1.00115.91 C ATOM 3 C SER A 6 -26.419 6.159 -6.970 1.00114.54 C ATOM 4 O SER A 6 -26.103 6.886 -7.915 1.00110.10 O ATOM 5 CB SER A 6 -25.744 4.037 -8.113 1.00116.34 C ATOM 6 OG SER A 6 -26.087 2.689 -8.379 1.00121.40 O ATOM 7 N SER A 7 -26.458 6.572 -5.703 1.00116.37 N ATOM 8 CA SER A 7 -26.153 7.952 -5.306 1.00112.95 C ATOM 9 C SER A 7 -24.758 8.391 -5.751 1.00109.79 C ATOM 10 O SER A 7 -24.497 9.586 -5.902 1.00104.20 O ATOM 11 CB SER A 7 -26.313 8.125 -3.794 1.00113.79 C ATOM 12 OG SER A 7 -25.474 7.228 -3.088 1.00117.64 O ATOM 13 N VAL A 8 -23.879 7.409 -5.959 1.00108.84 N ATOM 14 CA VAL A 8 -22.535 7.626 -6.501 1.00108.75 C ATOM 15 C VAL A 8 -22.622 8.258 -7.895 1.00110.01 C ATOM 16 O VAL A 8 -21.895 9.207 -8.205 1.00105.91 O ATOM 17 CB VAL A 8 -21.739 6.295 -6.599 1.00108.46 C ATOM 18 CG1 VAL A 8 -20.240 6.568 -6.638 1.00107.74 C ATOM 19 CG2 VAL A 8 -22.087 5.355 -5.443 1.00105.56 C ATOM 20 N TYR A 9 -23.521 7.717 -8.719 1.00108.80 N ATOM 21 CA TYR A 9 -23.812 8.252 -10.048 1.00102.10 C ATOM 22 C TYR A 9 -24.618 9.551 -9.966 1.00 98.51 C ATOM 23 O TYR A 9 -24.331 10.506 -10.688 1.00 94.86 O ATOM 24 CB TYR A 9 -24.538 7.197 -10.902 1.00101.84 C ATOM 25 CG TYR A 9 -25.437 7.762 -11.986 1.00103.84 C ATOM 26 CD1 TYR A 9 -24.909 8.232 -13.189 1.00103.66 C ATOM 27 CD2 TYR A 9 -26.819 7.825 -11.807 1.00104.86 C ATOM 28 CE1 TYR A 9 -25.736 8.751 -14.184 1.00102.53 C ATOM 29 CE2 TYR A 9 -27.653 8.344 -12.797 1.00102.95 C ATOM 30 CZ TYR A 9 -27.105 8.806 -13.980 1.00100.57 C ATOM 31 OH TYR A 9 -27.927 9.321 -14.955 1.00 98.99 O ATOM 32 N ILE A 10 -25.617 9.574 -9.083 1.00 98.03 N ATOM 33 CA ILE A 10 -26.502 10.732 -8.913 1.00 99.17 C ATOM 34 C ILE A 10 -25.729 12.005 -8.552 1.00101.67 C ATOM 35 O ILE A 10 -26.030 13.085 -9.068 1.00 99.28 O ATOM 36 CB ILE A 10 -27.599 10.484 -7.829 1.00 99.34 C ATOM 37 CG1 ILE A 10 -28.301 9.126 -8.018 1.00 98.58 C ATOM 38 CG2 ILE A 10 -28.601 11.649 -7.783 1.00 98.35 C ATOM 39 CD1 ILE A 10 -29.233 9.020 -9.216 1.00 99.47 C ATOM 40 N THR A 11 -24.739 11.871 -7.670 1.00105.43 N ATOM 41 CA THR A 11 -23.972 13.029 -7.195 1.00105.70 C ATOM 42 C THR A 11 -23.037 13.596 -8.270 1.00102.62 C ATOM 43 O THR A 11 -22.970 14.817 -8.458 1.00 99.19 O ATOM 44 CB THR A 11 -23.219 12.748 -5.854 1.00105.61 C ATOM 45 OG1 THR A 11 -22.552 13.939 -5.421 1.00106.61 O ATOM 46 CG2 THR A 11 -22.196 11.618 -5.992 1.00106.18 C ATOM 47 N VAL A 12 -22.337 12.707 -8.976 1.00 97.70 N ATOM 48 CA VAL A 12 -21.478 13.098 -10.092 1.00 95.87 C ATOM 49 C VAL A 12 -22.315 13.825 -11.142 1.00 96.43 C ATOM 50 O VAL A 12 -21.922 14.881 -11.638 1.00 98.69 O ATOM 51 CB VAL A 12 -20.755 11.876 -10.717 1.00 95.74 C ATOM 52 CG1 VAL A 12 -20.120 12.235 -12.058 1.00 93.12 C ATOM 53 CG2 VAL A 12 -19.706 11.326 -9.757 1.00 93.44 C ATOM 54 N GLU A 13 -23.482 13.261 -11.444 1.00 95.86 N ATOM 55 CA GLU A 13 -24.434 13.855 -12.379 1.00 95.75 C ATOM 56 C GLU A 13 -24.857 15.263 -11.945 1.00 93.57 C ATOM 57 O GLU A 13 -25.062 16.145 -12.782 1.00 93.41 O ATOM 58 CB GLU A 13 -25.658 12.944 -12.521 1.00 99.02 C ATOM 59 CG GLU A 13 -26.502 13.175 -13.771 1.00105.16 C ATOM 60 CD GLU A 13 -25.908 12.559 -15.029 1.00109.92 C ATOM 61 OE1 GLU A 13 -24.887 13.079 -15.530 1.00111.21 O ATOM 62 OE2 GLU A 13 -26.477 11.564 -15.531 1.00113.65 O1- ATOM 63 N LEU A 14 -24.973 15.466 -10.636 1.00 93.51 N ATOM 64 CA LEU A 14 -25.375 16.760 -10.085 1.00 91.34 C ATOM 65 C LEU A 14 -24.274 17.818 -10.187 1.00 89.07 C ATOM 66 O LEU A 14 -24.557 18.995 -10.440 1.00 84.61 O ATOM 67 CB LEU A 14 -25.848 16.604 -8.639 1.00 88.61 C ATOM 68 CG LEU A 14 -27.311 16.194 -8.470 1.00 84.88 C ATOM 69 CD1 LEU A 14 -27.531 15.545 -7.109 1.00 83.17 C ATOM 70 CD2 LEU A 14 -28.240 17.391 -8.680 1.00 79.86 C ATOM 71 N ALA A 15 -23.027 17.392 -9.997 1.00 84.17 N ATOM 72 CA ALA A 15 -21.880 18.277 -10.177 1.00 86.08 C ATOM 73 C ALA A 15 -21.915 18.930 -11.561 1.00 87.98 C ATOM 74 O ALA A 15 -21.848 20.162 -11.681 1.00 85.06 O ATOM 75 CB ALA A 15 -20.576 17.511 -9.971 1.00 83.80 C ATOM 76 N ILE A 16 -22.059 18.092 -12.591 1.00 87.17 N ATOM 77 CA ILE A 16 -22.041 18.524 -13.990 1.00 82.81 C ATOM 78 C ILE A 16 -23.135 19.541 -14.295 1.00 79.38 C ATOM 79 O ILE A 16 -22.901 20.498 -15.032 1.00 75.61 O ATOM 80 CB ILE A 16 -22.175 17.333 -14.959 1.00 85.78 C ATOM 81 CG1 ILE A 16 -21.212 16.213 -14.569 1.00 87.49 C ATOM 82 CG2 ILE A 16 -21.908 17.781 -16.399 1.00 90.27 C ATOM 83 CD1 ILE A 16 -21.601 14.864 -15.114 1.00 87.91 C ATOM 84 N ALA A 17 -24.321 19.329 -13.729 1.00 80.20 N ATOM 85 CA ALA A 17 -25.427 20.271 -13.885 1.00 83.44 C ATOM 86 C ALA A 17 -25.008 21.664 -13.420 1.00 84.48 C ATOM 87 O ALA A 17 -25.124 22.635 -14.170 1.00 81.66 O ATOM 88 CB ALA A 17 -26.658 19.789 -13.127 1.00 82.24 C ATOM 89 N VAL A 18 -24.490 21.739 -12.193 1.00 85.99 N ATOM 90 CA VAL A 18 -23.968 22.982 -11.627 1.00 85.48 C ATOM 91 C VAL A 18 -22.899 23.567 -12.550 1.00 84.60 C ATOM 92 O VAL A 18 -23.047 24.684 -13.045 1.00 84.89 O ATOM 93 CB VAL A 18 -23.398 22.765 -10.195 1.00 87.76 C ATOM 94 CG1 VAL A 18 -22.742 24.036 -9.667 1.00 87.22 C ATOM 95 CG2 VAL A 18 -24.495 22.296 -9.237 1.00 86.39 C ATOM 96 N LEU A 19 -21.845 22.792 -12.798 1.00 82.86 N ATOM 97 CA LEU A 19 -20.744 23.210 -13.666 1.00 83.57 C ATOM 98 C LEU A 19 -21.212 23.739 -15.025 1.00 87.51 C ATOM 99 O LEU A 19 -20.696 24.748 -15.511 1.00 92.29 O ATOM 100 CB LEU A 19 -19.755 22.062 -13.854 1.00 81.20 C ATOM 101 CG LEU A 19 -18.987 21.644 -12.598 1.00 83.10 C ATOM 102 CD1 LEU A 19 -18.603 20.175 -12.668 1.00 84.39 C ATOM 103 CD2 LEU A 19 -17.759 22.525 -12.371 1.00 81.94 C ATOM 104 N ALA A 20 -22.192 23.058 -15.622 1.00 86.38 N ATOM 105 CA ALA A 20 -22.781 23.485 -16.890 1.00 86.62 C ATOM 106 C ALA A 20 -23.545 24.799 -16.742 1.00 88.27 C ATOM 107 O ALA A 20 -23.465 25.669 -17.612 1.00 88.79 O ATOM 108 CB ALA A 20 -23.688 22.403 -17.454 1.00 86.31 C ATOM 109 N ILE A 21 -24.278 24.935 -15.639 1.00 89.19 N ATOM 110 CA ILE A 21 -25.014 26.165 -15.346 1.00 90.64 C ATOM 111 C ILE A 21 -24.053 27.331 -15.099 1.00 90.07 C ATOM 112 O ILE A 21 -24.238 28.413 -15.659 1.00 88.47 O ATOM 113 CB ILE A 21 -25.989 25.994 -14.149 1.00 90.48 C ATOM 114 CG1 ILE A 21 -27.050 24.937 -14.475 1.00 88.99 C ATOM 115 CG2 ILE A 21 -26.666 27.324 -13.807 1.00 88.76 C ATOM 116 CD1 ILE A 21 -27.689 24.296 -13.258 1.00 87.02 C ATOM 117 N LEU A 22 -23.022 27.099 -14.285 1.00 89.22 N ATOM 118 CA LEU A 22 -22.045 28.143 -13.951 1.00 90.57 C ATOM 119 C LEU A 22 -21.315 28.651 -15.192 1.00 90.14 C ATOM 120 O LEU A 22 -21.395 29.838 -15.522 1.00 89.09 O ATOM 121 CB LEU A 22 -21.039 27.654 -12.897 1.00 89.81 C ATOM 122 CG LEU A 22 -21.552 27.066 -11.574 1.00 90.17 C ATOM 123 CD1 LEU A 22 -20.394 26.700 -10.659 1.00 83.65 C ATOM 124 CD2 LEU A 22 -22.547 27.984 -10.858 1.00 88.90 C ATOM 125 N GLY A 23 -20.629 27.742 -15.882 1.00 88.42 N ATOM 126 CA GLY A 23 -19.882 28.071 -17.094 1.00 87.68 C ATOM 127 C GLY A 23 -20.688 28.774 -18.173 1.00 88.69 C ATOM 128 O GLY A 23 -20.190 29.694 -18.823 1.00 87.10 O ATOM 129 N ASN A 24 -21.936 28.354 -18.365 1.00 87.38 N ATOM 130 CA ASN A 24 -22.755 28.909 -19.443 1.00 88.59 C ATOM 131 C ASN A 24 -23.508 30.180 -19.073 1.00 88.15 C ATOM 132 O ASN A 24 -23.793 31.005 -19.944 1.00 86.62 O ATOM 133 CB ASN A 24 -23.684 27.847 -20.032 1.00 90.19 C ATOM 134 CG ASN A 24 -22.928 26.793 -20.821 1.00 90.89 C ATOM 135 OD1 ASN A 24 -22.458 27.047 -21.933 1.00 87.07 O ATOM 136 ND2 ASN A 24 -22.795 25.606 -20.241 1.00 89.90 N ATOM 137 N VAL A 25 -23.826 30.333 -17.787 1.00 90.64 N ATOM 138 CA VAL A 25 -24.305 31.615 -17.262 1.00 90.30 C ATOM 139 C VAL A 25 -23.168 32.627 -17.388 1.00 88.42 C ATOM 140 O VAL A 25 -23.379 33.753 -17.840 1.00 83.20 O ATOM 141 CB VAL A 25 -24.808 31.505 -15.794 1.00 90.16 C ATOM 142 CG1 VAL A 25 -24.805 32.860 -15.094 1.00 88.97 C ATOM 143 CG2 VAL A 25 -26.205 30.898 -15.756 1.00 91.21 C ATOM 144 N LEU A 26 -21.964 32.194 -17.013 1.00 90.52 N ATOM 145 CA LEU A 26 -20.748 32.986 -17.172 1.00 93.20 C ATOM 146 C LEU A 26 -20.600 33.477 -18.614 1.00 94.54 C ATOM 147 O LEU A 26 -20.361 34.668 -18.844 1.00 95.98 O ATOM 148 CB LEU A 26 -19.522 32.165 -16.752 1.00 94.78 C ATOM 149 CG LEU A 26 -18.323 32.866 -16.104 1.00100.09 C ATOM 150 CD1 LEU A 26 -18.681 33.438 -14.734 1.00 99.07 C ATOM 151 CD2 LEU A 26 -17.150 31.901 -15.982 1.00102.03 C ATOM 152 N VAL A 27 -20.766 32.558 -19.571 1.00 91.90 N ATOM 153 CA VAL A 27 -20.680 32.867 -21.004 1.00 86.71 C ATOM 154 C VAL A 27 -21.737 33.884 -21.412 1.00 86.39 C ATOM 155 O VAL A 27 -21.434 34.849 -22.112 1.00 86.10 O ATOM 156 CB VAL A 27 -20.808 31.592 -21.886 1.00 86.74 C ATOM 157 CG1 VAL A 27 -20.890 31.950 -23.375 1.00 81.23 C ATOM 158 CG2 VAL A 27 -19.641 30.646 -21.639 1.00 87.28 C ATOM 159 N CYS A 28 -22.971 33.665 -20.964 1.00 90.25 N ATOM 160 CA CYS A 28 -24.085 34.551 -21.294 1.00 94.45 C ATOM 161 C CYS A 28 -23.952 35.913 -20.623 1.00 95.94 C ATOM 162 O CYS A 28 -24.202 36.948 -21.250 1.00 93.23 O ATOM 163 CB CYS A 28 -25.415 33.896 -20.929 1.00 97.62 C ATOM 164 SG CYS A 28 -25.828 32.502 -21.991 1.00105.09 S ATOM 165 N TRP A 29 -23.550 35.897 -19.352 1.00100.30 N ATOM 166 CA TRP A 29 -23.250 37.112 -18.596 1.00104.53 C ATOM 167 C TRP A 29 -22.278 37.986 -19.389 1.00102.34 C ATOM 168 O TRP A 29 -22.559 39.156 -19.658 1.00103.00 O ATOM 169 CB TRP A 29 -22.632 36.751 -17.239 1.00110.20 C ATOM 170 CG TRP A 29 -23.013 37.655 -16.090 1.00114.61 C ATOM 171 CD1 TRP A 29 -23.346 38.982 -16.155 1.00117.41 C ATOM 172 CD2 TRP A 29 -23.068 37.298 -14.701 1.00116.34 C ATOM 173 NE1 TRP A 29 -23.621 39.464 -14.896 1.00118.84 N ATOM 174 CE2 TRP A 29 -23.455 38.454 -13.986 1.00117.66 C ATOM 175 CE3 TRP A 29 -22.833 36.110 -13.992 1.00116.94 C ATOM 176 CZ2 TRP A 29 -23.613 38.458 -12.594 1.00117.51 C ATOM 177 CZ3 TRP A 29 -22.991 36.115 -12.606 1.00117.43 C ATOM 178 CH2 TRP A 29 -23.377 37.283 -11.925 1.00116.00 C ATOM 179 N ALA A 30 -21.155 37.385 -19.786 1.00 97.98 N ATOM 180 CA ALA A 30 -20.077 38.070 -20.501 1.00 98.64 C ATOM 181 C ALA A 30 -20.519 38.842 -21.747 1.00 99.19 C ATOM 182 O ALA A 30 -19.930 39.869 -22.078 1.00103.95 O ATOM 183 CB ALA A 30 -18.967 37.085 -20.854 1.00 98.70 C ATOM 184 N VAL A 31 -21.549 38.352 -22.430 1.00 99.96 N ATOM 185 CA VAL A 31 -22.017 38.987 -23.665 1.00105.09 C ATOM 186 C VAL A 31 -22.909 40.196 -23.364 1.00108.34 C ATOM 187 O VAL A 31 -23.003 41.126 -24.172 1.00104.41 O ATOM 188 CB VAL A 31 -22.741 37.978 -24.603 1.00104.48 C ATOM 189 CG1 VAL A 31 -23.027 38.602 -25.969 1.00 98.04 C ATOM 190 CG2 VAL A 31 -21.907 36.714 -24.775 1.00103.10 C ATOM 191 N TRP A 32 -23.554 40.180 -22.199 1.00114.42 N ATOM 192 CA TRP A 32 -24.401 41.294 -21.774 1.00119.96 C ATOM 193 C TRP A 32 -23.559 42.509 -21.374 1.00120.24 C ATOM 194 O TRP A 32 -23.851 43.633 -21.790 1.00119.24 O ATOM 195 CB TRP A 32 -25.342 40.869 -20.635 1.00125.31 C ATOM 196 CG TRP A 32 -26.345 41.929 -20.221 1.00130.52 C ATOM 197 CD1 TRP A 32 -27.102 42.713 -21.048 1.00130.72 C ATOM 198 CD2 TRP A 32 -26.707 42.297 -18.879 1.00135.45 C ATOM 199 NE1 TRP A 32 -27.901 43.553 -20.307 1.00134.14 N ATOM 200 CE2 TRP A 32 -27.681 43.319 -18.975 1.00136.95 C ATOM 201 CE3 TRP A 32 -26.300 41.867 -17.606 1.00136.88 C ATOM 202 CZ2 TRP A 32 -28.257 43.919 -17.844 1.00138.17 C ATOM 203 CZ3 TRP A 32 -26.874 42.465 -16.481 1.00137.35 C ATOM 204 CH2 TRP A 32 -27.842 43.480 -16.611 1.00137.23 C ATOM 205 N LEU A 33 -22.509 42.268 -20.588 1.00118.91 N ATOM 206 CA LEU A 33 -21.625 43.331 -20.099 1.00117.75 C ATOM 207 C LEU A 33 -20.729 43.906 -21.205 1.00120.38 C ATOM 208 O LEU A 33 -20.872 45.073 -21.578 1.00124.66 O ATOM 209 CB LEU A 33 -20.777 42.835 -18.917 1.00113.80 C ATOM 210 CG LEU A 33 -21.500 42.265 -17.687 1.00114.13 C ATOM 211 CD1 LEU A 33 -20.554 41.409 -16.857 1.00113.93 C ATOM 212 CD2 LEU A 33 -22.135 43.352 -16.826 1.00110.73 C ATOM 213 N ASN A 34 -19.822 43.081 -21.728 1.00117.26 N ATOM 214 CA ASN A 34 -18.866 43.510 -22.750 1.00113.47 C ATOM 215 C ASN A 34 -19.530 43.847 -24.085 1.00111.25 C ATOM 216 O ASN A 34 -20.013 42.960 -24.791 1.00117.02 O ATOM 217 CB ASN A 34 -17.779 42.447 -22.939 1.00112.13 C ATOM 218 CG ASN A 34 -16.625 42.927 -23.805 1.00112.20 C ATOM 219 OD1 ASN A 34 -16.815 43.660 -24.780 1.00104.31 O ATOM 220 ND2 ASN A 34 -15.416 42.502 -23.454 1.00111.28 N ATOM 221 N SER A 35 -19.526 45.133 -24.426 1.00109.63 N ATOM 222 CA SER A 35 -20.206 45.639 -25.618 1.00108.32 C ATOM 223 C SER A 35 -19.540 45.220 -26.935 1.00110.38 C ATOM 224 O SER A 35 -20.177 45.250 -27.991 1.00110.54 O ATOM 225 CB SER A 35 -20.340 47.161 -25.545 1.00105.99 C ATOM 226 OG SER A 35 -21.218 47.641 -26.547 1.00106.51 O ATOM 227 N ASN A 36 -18.265 44.841 -26.870 1.00113.90 N ATOM 228 CA ASN A 36 -17.541 44.345 -28.046 1.00115.81 C ATOM 229 C ASN A 36 -18.011 42.949 -28.453 1.00114.33 C ATOM 230 O ASN A 36 -17.946 42.580 -29.628 1.00113.95 O ATOM 231 CB ASN A 36 -16.027 44.329 -27.797 1.00117.03 C ATOM 232 CG ASN A 36 -15.455 45.712 -27.548 1.00115.16 C ATOM 233 OD1 ASN A 36 -15.662 46.637 -28.335 1.00115.74 O ATOM 234 ND2 ASN A 36 -14.719 45.855 -26.451 1.00113.47 N ATOM 235 N LEU A 37 -18.490 42.189 -27.469 1.00109.98 N ATOM 236 CA LEU A 37 -18.965 40.824 -27.682 1.00104.40 C ATOM 237 C LEU A 37 -20.320 40.758 -28.388 1.00105.88 C ATOM 238 O LEU A 37 -20.745 39.688 -28.821 1.00112.08 O ATOM 239 CB LEU A 37 -19.024 40.067 -26.349 1.00 97.59 C ATOM 240 CG LEU A 37 -17.705 39.813 -25.608 1.00 95.64 C ATOM 241 CD1 LEU A 37 -17.920 38.946 -24.379 1.00 91.06 C ATOM 242 CD2 LEU A 37 -16.671 39.175 -26.519 1.00 99.26 C ATOM 243 N GLN A 38 -20.985 41.902 -28.521 1.00106.06 N ATOM 244 CA GLN A 38 -22.349 41.946 -29.047 1.00105.78 C ATOM 245 C GLN A 38 -22.412 42.043 -30.570 1.00105.58 C ATOM 246 O GLN A 38 -22.870 43.045 -31.120 1.00109.27 O ATOM 247 CB GLN A 38 -23.142 43.080 -28.386 1.00107.50 C ATOM 248 CG GLN A 38 -23.236 42.942 -26.869 1.00108.41 C ATOM 249 CD GLN A 38 -24.092 44.005 -26.205 1.00107.66 C ATOM 250 OE1 GLN A 38 -24.593 44.927 -26.854 1.00107.17 O ATOM 251 NE2 GLN A 38 -24.264 43.876 -24.895 1.00107.53 N ATOM 252 N ASN A 39 -21.949 40.990 -31.241 1.00106.87 N ATOM 253 CA ASN A 39 -22.072 40.874 -32.697 1.00107.12 C ATOM 254 C ASN A 39 -22.711 39.551 -33.135 1.00107.58 C ATOM 255 O ASN A 39 -22.892 38.639 -32.322 1.00106.86 O ATOM 256 CB ASN A 39 -20.718 41.092 -33.388 1.00107.78 C ATOM 257 CG ASN A 39 -19.651 40.117 -32.919 1.00109.94 C ATOM 258 OD1 ASN A 39 -19.444 39.929 -31.719 1.00112.72 O ATOM 259 ND2 ASN A 39 -18.957 39.504 -33.870 1.00109.31 N ATOM 260 N VAL A 40 -23.043 39.465 -34.424 1.00109.73 N ATOM 261 CA VAL A 40 -23.749 38.318 -35.016 1.00106.49 C ATOM 262 C VAL A 40 -23.102 36.970 -34.671 1.00105.01 C ATOM 263 O VAL A 40 -23.794 36.012 -34.325 1.00101.79 O ATOM 264 CB VAL A 40 -23.864 38.461 -36.563 1.00108.22 C ATOM 265 CG1 VAL A 40 -24.782 37.395 -37.138 1.00110.16 C ATOM 266 CG2 VAL A 40 -24.374 39.845 -36.946 1.00109.18 C ATOM 267 N THR A 41 -21.776 36.917 -34.759 1.00105.24 N ATOM 268 CA THR A 41 -20.993 35.712 -34.473 1.00104.26 C ATOM 269 C THR A 41 -21.300 35.095 -33.104 1.00105.19 C ATOM 270 O THR A 41 -21.248 33.874 -32.937 1.00107.01 O ATOM 271 CB THR A 41 -19.481 36.020 -34.565 1.00102.50 C ATOM 272 OG1 THR A 41 -19.198 36.634 -35.828 1.00100.67 O ATOM 273 CG2 THR A 41 -18.640 34.753 -34.418 1.00102.61 C ATOM 274 N ASN A 42 -21.625 35.941 -32.132 1.00104.69 N ATOM 275 CA ASN A 42 -21.802 35.489 -30.757 1.00105.59 C ATOM 276 C ASN A 42 -23.239 35.151 -30.367 1.00104.03 C ATOM 277 O ASN A 42 -23.474 34.596 -29.292 1.00 99.03 O ATOM 278 CB ASN A 42 -21.177 36.491 -29.791 1.00110.13 C ATOM 279 CG ASN A 42 -19.668 36.526 -29.904 1.00115.15 C ATOM 280 OD1 ASN A 42 -18.981 35.615 -29.441 1.00116.78 O ATOM 281 ND2 ASN A 42 -19.142 37.572 -30.534 1.00113.90 N ATOM 282 N TYR A 43 -24.187 35.483 -31.245 1.00104.66 N ATOM 283 CA TYR A 43 -25.553 34.964 -31.152 1.00102.28 C ATOM 284 C TYR A 43 -25.478 33.448 -31.002 1.00 96.74 C ATOM 285 O TYR A 43 -25.951 32.887 -30.010 1.00 94.56 O ATOM 286 CB TYR A 43 -26.354 35.314 -32.413 1.00108.24 C ATOM 287 CG TYR A 43 -27.077 36.646 -32.384 1.00119.74 C ATOM 288 CD1 TYR A 43 -26.379 37.850 -32.241 1.00125.61 C ATOM 289 CD2 TYR A 43 -28.462 36.704 -32.530 1.00124.98 C ATOM 290 CE1 TYR A 43 -27.051 39.077 -32.224 1.00129.58 C ATOM 291 CE2 TYR A 43 -29.141 37.921 -32.517 1.00128.93 C ATOM 292 CZ TYR A 43 -28.432 39.101 -32.365 1.00130.27 C ATOM 293 OH TYR A 43 -29.110 40.298 -32.354 1.00130.78 O ATOM 294 N PHE A 44 -24.836 32.811 -31.983 1.00 90.54 N ATOM 295 CA PHE A 44 -24.659 31.361 -32.036 1.00 84.73 C ATOM 296 C PHE A 44 -23.992 30.782 -30.790 1.00 86.37 C ATOM 297 O PHE A 44 -24.214 29.616 -30.451 1.00 89.49 O ATOM 298 CB PHE A 44 -23.853 30.974 -33.277 1.00 81.94 C ATOM 299 CG PHE A 44 -24.410 31.519 -34.565 1.00 80.51 C ATOM 300 CD1 PHE A 44 -25.620 31.055 -35.072 1.00 79.57 C ATOM 301 CD2 PHE A 44 -23.719 32.494 -35.275 1.00 82.08 C ATOM 302 CE1 PHE A 44 -26.136 31.558 -36.263 1.00 81.82 C ATOM 303 CE2 PHE A 44 -24.226 33.003 -36.473 1.00 83.82 C ATOM 304 CZ PHE A 44 -25.435 32.533 -36.968 1.00 83.17 C ATOM 305 N VAL A 45 -23.183 31.596 -30.114 1.00 84.57 N ATOM 306 CA VAL A 45 -22.516 31.177 -28.879 1.00 81.35 C ATOM 307 C VAL A 45 -23.489 31.218 -27.701 1.00 80.53 C ATOM 308 O VAL A 45 -23.500 30.303 -26.875 1.00 79.48 O ATOM 309 CB VAL A 45 -21.254 32.030 -28.571 1.00 79.43 C ATOM 310 CG1 VAL A 45 -20.547 31.516 -27.329 1.00 75.74 C ATOM 311 CG2 VAL A 45 -20.296 32.019 -29.753 1.00 80.15 C ATOM 312 N VAL A 46 -24.302 32.273 -27.635 1.00 83.35 N ATOM 313 CA VAL A 46 -25.285 32.432 -26.554 1.00 86.01 C ATOM 314 C VAL A 46 -26.368 31.361 -26.670 1.00 84.57 C ATOM 315 O VAL A 46 -26.760 30.760 -25.663 1.00 81.29 O ATOM 316 CB VAL A 46 -25.933 33.851 -26.526 1.00 88.30 C ATOM 317 CG1 VAL A 46 -26.806 34.024 -25.280 1.00 85.27 C ATOM 318 CG2 VAL A 46 -24.866 34.939 -26.562 1.00 88.14 C ATOM 319 N SER A 47 -26.828 31.130 -27.903 1.00 80.82 N ATOM 320 CA SER A 47 -27.784 30.067 -28.210 1.00 76.74 C ATOM 321 C SER A 47 -27.293 28.752 -27.629 1.00 75.32 C ATOM 322 O SER A 47 -27.988 28.125 -26.830 1.00 75.00 O ATOM 323 CB SER A 47 -27.963 29.907 -29.724 1.00 79.91 C ATOM 324 OG SER A 47 -28.079 31.153 -30.386 1.00 81.24 O ATOM 325 N ALA A 48 -26.085 28.352 -28.027 1.00 72.30 N ATOM 326 CA ALA A 48 -25.492 27.102 -27.564 1.00 73.36 C ATOM 327 C ALA A 48 -25.323 27.074 -26.048 1.00 75.78 C ATOM 328 O ALA A 48 -25.603 26.058 -25.411 1.00 77.02 O ATOM 329 CB ALA A 48 -24.178 26.836 -28.269 1.00 70.80 C ATOM 330 N ALA A 49 -24.892 28.198 -25.477 1.00 78.99 N ATOM 331 CA ALA A 49 -24.756 28.327 -24.028 1.00 82.10 C ATOM 332 C ALA A 49 -26.115 28.279 -23.327 1.00 84.02 C ATOM 333 O ALA A 49 -26.229 27.705 -22.241 1.00 86.89 O ATOM 334 CB ALA A 49 -24.003 29.601 -23.666 1.00 81.70 C ATOM 335 N ALA A 50 -27.134 28.872 -23.955 1.00 80.90 N ATOM 336 CA ALA A 50 -28.508 28.841 -23.440 1.00 79.82 C ATOM 337 C ALA A 50 -29.033 27.408 -23.316 1.00 79.92 C ATOM 338 O ALA A 50 -29.583 27.026 -22.281 1.00 78.73 O ATOM 339 CB ALA A 50 -29.432 29.675 -24.325 1.00 76.77 C ATOM 340 N ALA A 51 -28.842 26.625 -24.376 1.00 79.93 N ATOM 341 CA ALA A 51 -29.252 25.223 -24.415 1.00 78.55 C ATOM 342 C ALA A 51 -28.614 24.394 -23.299 1.00 79.15 C ATOM 343 O ALA A 51 -29.296 23.609 -22.645 1.00 79.04 O ATOM 344 CB ALA A 51 -28.934 24.621 -25.780 1.00 76.99 C ATOM 345 N ASP A 52 -27.313 24.583 -23.080 1.00 81.25 N ATOM 346 CA ASP A 52 -26.577 23.843 -22.050 1.00 84.14 C ATOM 347 C ASP A 52 -27.048 24.192 -20.641 1.00 85.14 C ATOM 348 O ASP A 52 -26.994 23.356 -19.732 1.00 82.42 O ATOM 349 CB ASP A 52 -25.076 24.102 -22.166 1.00 87.43 C ATOM 350 CG ASP A 52 -24.507 23.670 -23.505 1.00 93.93 C ATOM 351 OD1 ASP A 52 -24.747 22.520 -23.935 1.00 97.38 O ATOM 352 OD2 ASP A 52 -23.807 24.488 -24.130 1.00 95.90 O1- ATOM 353 N ILE A 53 -27.493 25.436 -20.464 1.00 84.06 N ATOM 354 CA ILE A 53 -28.126 25.848 -19.220 1.00 82.46 C ATOM 355 C ILE A 53 -29.375 24.997 -19.041 1.00 83.00 C ATOM 356 O ILE A 53 -29.525 24.323 -18.022 1.00 85.98 O ATOM 357 CB ILE A 53 -28.467 27.357 -19.207 1.00 81.24 C ATOM 358 CG1 ILE A 53 -27.183 28.186 -19.102 1.00 81.26 C ATOM 359 CG2 ILE A 53 -29.401 27.689 -18.044 1.00 78.12 C ATOM 360 CD1 ILE A 53 -27.298 29.594 -19.645 1.00 81.42 C ATOM 361 N LEU A 54 -30.241 25.004 -20.057 1.00 81.07 N ATOM 362 CA LEU A 54 -31.457 24.188 -20.069 1.00 76.44 C ATOM 363 C LEU A 54 -31.158 22.697 -19.868 1.00 76.54 C ATOM 364 O LEU A 54 -31.977 21.969 -19.309 1.00 77.14 O ATOM 365 CB LEU A 54 -32.247 24.412 -21.364 1.00 73.88 C ATOM 366 CG LEU A 54 -32.934 25.769 -21.578 1.00 74.67 C ATOM 367 CD1 LEU A 54 -33.326 25.975 -23.039 1.00 74.24 C ATOM 368 CD2 LEU A 54 -34.157 25.931 -20.682 1.00 75.42 C ATOM 369 N VAL A 55 -29.984 22.255 -20.318 1.00 73.83 N ATOM 370 CA VAL A 55 -29.535 20.882 -20.088 1.00 75.33 C ATOM 371 C VAL A 55 -29.197 20.658 -18.610 1.00 79.82 C ATOM 372 O VAL A 55 -29.536 19.616 -18.039 1.00 77.02 O ATOM 373 CB VAL A 55 -28.317 20.511 -20.978 1.00 74.29 C ATOM 374 CG1 VAL A 55 -27.787 19.114 -20.633 1.00 68.55 C ATOM 375 CG2 VAL A 55 -28.683 20.597 -22.457 1.00 74.70 C ATOM 376 N GLY A 56 -28.530 21.641 -18.005 1.00 84.58 N ATOM 377 CA GLY A 56 -28.170 21.585 -16.589 1.00 83.77 C ATOM 378 C GLY A 56 -29.373 21.761 -15.682 1.00 83.38 C ATOM 379 O GLY A 56 -29.518 21.051 -14.688 1.00 86.99 O ATOM 380 N VAL A 57 -30.240 22.703 -16.039 1.00 81.17 N ATOM 381 CA VAL A 57 -31.421 23.029 -15.245 1.00 84.79 C ATOM 382 C VAL A 57 -32.531 21.978 -15.362 1.00 90.45 C ATOM 383 O VAL A 57 -33.069 21.533 -14.348 1.00 94.08 O ATOM 384 CB VAL A 57 -31.979 24.428 -15.616 1.00 84.37 C ATOM 385 CG1 VAL A 57 -33.301 24.692 -14.914 1.00 85.30 C ATOM 386 CG2 VAL A 57 -30.972 25.515 -15.265 1.00 86.66 C ATOM 387 N LEU A 58 -32.864 21.586 -16.593 1.00 94.34 N ATOM 388 CA LEU A 58 -34.013 20.707 -16.850 1.00 88.07 C ATOM 389 C LEU A 58 -33.656 19.261 -17.225 1.00 88.91 C ATOM 390 O LEU A 58 -34.196 18.323 -16.637 1.00 91.03 O ATOM 391 CB LEU A 58 -34.931 21.320 -17.915 1.00 84.12 C ATOM 392 CG LEU A 58 -35.748 22.565 -17.554 1.00 84.06 C ATOM 393 CD1 LEU A 58 -36.093 23.359 -18.802 1.00 82.41 C ATOM 394 CD2 LEU A 58 -37.014 22.203 -16.788 1.00 83.95 C ATOM 395 N ALA A 59 -32.748 19.086 -18.186 1.00 89.21 N ATOM 396 CA ALA A 59 -32.454 17.759 -18.752 1.00 86.39 C ATOM 397 C ALA A 59 -31.762 16.799 -17.790 1.00 84.17 C ATOM 398 O ALA A 59 -32.154 15.636 -17.690 1.00 85.23 O ATOM 399 CB ALA A 59 -31.658 17.879 -20.051 1.00 84.19 C ATOM 400 N ILE A 60 -30.737 17.279 -17.092 1.00 85.50 N ATOM 401 CA ILE A 60 -29.982 16.431 -16.160 1.00 87.68 C ATOM 402 C ILE A 60 -30.810 16.019 -14.927 1.00 87.45 C ATOM 403 O ILE A 60 -30.704 14.874 -14.480 1.00 88.06 O ATOM 404 CB ILE A 60 -28.601 17.042 -15.778 1.00 88.46 C ATOM 405 CG1 ILE A 60 -27.729 17.205 -17.031 1.00 91.51 C ATOM 406 CG2 ILE A 60 -27.882 16.158 -14.768 1.00 87.37 C ATOM 407 CD1 ILE A 60 -26.552 18.162 -16.883 1.00 91.65 C ATOM 408 N PRO A 61 -31.640 16.941 -14.382 1.00 87.40 N ATOM 409 CA PRO A 61 -32.584 16.523 -13.347 1.00 85.61 C ATOM 410 C PRO A 61 -33.485 15.383 -13.826 1.00 85.80 C ATOM 411 O PRO A 61 -33.591 14.353 -13.149 1.00 86.43 O ATOM 412 CB PRO A 61 -33.412 17.787 -13.108 1.00 85.27 C ATOM 413 CG PRO A 61 -32.498 18.886 -13.417 1.00 81.41 C ATOM 414 CD PRO A 61 -31.650 18.408 -14.553 1.00 85.82 C ATOM 415 N PHE A 62 -34.110 15.569 -14.989 1.00 84.27 N ATOM 416 CA PHE A 62 -34.959 14.544 -15.599 1.00 83.72 C ATOM 417 C PHE A 62 -34.213 13.226 -15.829 1.00 84.33 C ATOM 418 O PHE A 62 -34.742 12.156 -15.538 1.00 84.62 O ATOM 419 CB PHE A 62 -35.554 15.043 -16.917 1.00 82.80 C ATOM 420 CG PHE A 62 -36.612 16.102 -16.756 1.00 84.50 C ATOM 421 CD1 PHE A 62 -37.303 16.254 -15.557 1.00 83.77 C ATOM 422 CD2 PHE A 62 -36.946 16.926 -17.827 1.00 86.13 C ATOM 423 CE1 PHE A 62 -38.287 17.228 -15.420 1.00 85.68 C ATOM 424 CE2 PHE A 62 -37.933 17.902 -17.699 1.00 87.74 C ATOM 425 CZ PHE A 62 -38.604 18.053 -16.494 1.00 86.69 C ATOM 426 N ALA A 63 -32.982 13.317 -16.334 1.00 82.67 N ATOM 427 CA ALA A 63 -32.133 12.150 -16.564 1.00 83.10 C ATOM 428 C ALA A 63 -31.849 11.359 -15.286 1.00 85.63 C ATOM 429 O ALA A 63 -31.634 10.143 -15.342 1.00 83.43 O ATOM 430 CB ALA A 63 -30.830 12.573 -17.222 1.00 83.99 C ATOM 431 N ILE A 64 -31.840 12.057 -14.148 1.00 88.35 N ATOM 432 CA ILE A 64 -31.620 11.435 -12.836 1.00 91.58 C ATOM 433 C ILE A 64 -32.843 10.623 -12.395 1.00 90.21 C ATOM 434 O ILE A 64 -32.705 9.500 -11.897 1.00 87.76 O ATOM 435 CB ILE A 64 -31.209 12.486 -11.756 1.00 94.46 C ATOM 436 CG1 ILE A 64 -29.752 12.914 -11.965 1.00 96.62 C ATOM 437 CG2 ILE A 64 -31.389 11.934 -10.337 1.00 93.64 C ATOM 438 CD1 ILE A 64 -29.341 14.163 -11.203 1.00 95.39 C ATOM 439 N ALA A 65 -34.030 11.194 -12.595 1.00 86.59 N ATOM 440 CA ALA A 65 -35.292 10.526 -12.274 1.00 86.77 C ATOM 441 C ALA A 65 -35.448 9.199 -13.022 1.00 85.87 C ATOM 442 O ALA A 65 -35.832 8.183 -12.440 1.00 84.78 O ATOM 443 CB ALA A 65 -36.463 11.451 -12.583 1.00 85.35 C ATOM 444 N ILE A 66 -35.120 9.229 -14.311 1.00 87.60 N ATOM 445 CA ILE A 66 -35.266 8.095 -15.225 1.00 88.91 C ATOM 446 C ILE A 66 -34.389 6.887 -14.850 1.00 91.35 C ATOM 447 O ILE A 66 -34.632 5.770 -15.320 1.00 91.84 O ATOM 448 CB ILE A 66 -34.977 8.550 -16.696 1.00 89.04 C ATOM 449 CG1 ILE A 66 -35.925 9.680 -17.138 1.00 88.85 C ATOM 450 CG2 ILE A 66 -35.044 7.401 -17.670 1.00 88.74 C ATOM 451 CD1 ILE A 66 -37.409 9.416 -16.937 1.00 88.24 C ATOM 452 N SER A 67 -33.387 7.110 -13.999 1.00 94.01 N ATOM 453 CA SER A 67 -32.442 6.054 -13.616 1.00 96.47 C ATOM 454 C SER A 67 -32.918 5.230 -12.422 1.00 95.80 C ATOM 455 O SER A 67 -32.413 4.130 -12.183 1.00 96.24 O ATOM 456 CB SER A 67 -31.051 6.639 -13.333 1.00 98.34 C ATOM 457 OG SER A 67 -31.074 7.527 -12.228 1.00 96.52 O ATOM 458 N THR A 68 -33.889 5.766 -11.685 1.00 97.16 N ATOM 459 CA THR A 68 -34.374 5.142 -10.451 1.00 99.82 C ATOM 460 C THR A 68 -35.402 4.050 -10.713 1.00102.25 C ATOM 461 O THR A 68 -35.464 3.058 -9.985 1.00107.56 O ATOM 462 CB THR A 68 -35.002 6.176 -9.498 1.00 99.38 C ATOM 463 OG1 THR A 68 -36.063 6.869 -10.170 1.00 98.25 O ATOM 464 CG2 THR A 68 -33.954 7.175 -9.019 1.00 98.12 C ATOM 465 N GLY A 69 -36.208 4.242 -11.752 1.00103.16 N ATOM 466 CA GLY A 69 -37.261 3.296 -12.094 1.00100.31 C ATOM 467 C GLY A 69 -38.481 3.492 -11.223 1.00 98.40 C ATOM 468 O GLY A 69 -39.058 2.523 -10.729 1.00101.12 O ATOM 469 N PHE A 70 -38.872 4.752 -11.039 1.00 94.33 N ATOM 470 CA PHE A 70 -40.030 5.093 -10.221 1.00 95.00 C ATOM 471 C PHE A 70 -41.348 4.715 -10.894 1.00101.30 C ATOM 472 O PHE A 70 -41.402 4.528 -12.110 1.00107.08 O ATOM 473 CB PHE A 70 -40.015 6.581 -9.839 1.00 91.53 C ATOM 474 CG PHE A 70 -40.145 7.523 -11.007 1.00 86.41 C ATOM 475 CD1 PHE A 70 -41.398 7.930 -11.457 1.00 84.67 C ATOM 476 CD2 PHE A 70 -39.015 8.027 -11.639 1.00 85.60 C ATOM 477 CE1 PHE A 70 -41.522 8.812 -12.531 1.00 83.72 C ATOM 478 CE2 PHE A 70 -39.131 8.911 -12.712 1.00 84.87 C ATOM 479 CZ PHE A 70 -40.387 9.303 -13.158 1.00 82.71 C ATOM 480 N CYS A 71 -42.403 4.603 -10.090 1.00107.43 N ATOM 481 CA CYS A 71 -43.722 4.226 -10.588 1.00103.66 C ATOM 482 C CYS A 71 -44.467 5.431 -11.145 1.00 98.05 C ATOM 483 O CYS A 71 -44.732 6.396 -10.429 1.00 98.62 O ATOM 484 CB CYS A 71 -44.544 3.550 -9.488 1.00106.89 C ATOM 485 SG CYS A 71 -43.756 2.098 -8.760 1.00122.69 S ATOM 486 N ALA A 72 -44.781 5.366 -12.435 1.00 95.02 N ATOM 487 CA ALA A 72 -45.618 6.361 -13.098 1.00 94.41 C ATOM 488 C ALA A 72 -46.245 5.752 -14.343 1.00 92.05 C ATOM 489 O ALA A 72 -45.936 4.614 -14.709 1.00 87.74 O ATOM 490 CB ALA A 72 -44.808 7.601 -13.462 1.00 97.71 C ATOM 491 N ALA A 73 -47.131 6.514 -14.981 1.00 91.57 N ATOM 492 CA ALA A 73 -47.736 6.105 -16.241 1.00 95.92 C ATOM 493 C ALA A 73 -46.662 6.023 -17.317 1.00 98.81 C ATOM 494 O ALA A 73 -45.751 6.853 -17.353 1.00100.79 O ATOM 495 CB ALA A 73 -48.824 7.082 -16.649 1.00 94.83 C ATOM 496 N CYS A 74 -46.769 5.012 -18.176 1.00101.58 N ATOM 497 CA CYS A 74 -45.815 4.808 -19.261 1.00102.05 C ATOM 498 C CYS A 74 -45.672 6.065 -20.113 1.00104.18 C ATOM 499 O CYS A 74 -44.557 6.532 -20.354 1.00105.98 O ATOM 500 CB CYS A 74 -46.231 3.626 -20.141 1.00104.02 C ATOM 501 SG CYS A 74 -44.970 3.120 -21.346 1.00107.84 S ATOM 502 N HIS A 75 -46.804 6.610 -20.557 1.00103.11 N ATOM 503 CA HIS A 75 -46.804 7.790 -21.422 1.00100.94 C ATOM 504 C HIS A 75 -46.337 9.056 -20.707 1.00 96.76 C ATOM 505 O HIS A 75 -45.946 10.028 -21.353 1.00 97.98 O ATOM 506 CB HIS A 75 -48.171 7.983 -22.081 1.00102.85 C ATOM 507 CG HIS A 75 -48.439 7.014 -23.189 1.00107.56 C ATOM 508 ND1 HIS A 75 -49.067 5.804 -22.983 1.00112.97 N ATOM 509 CD2 HIS A 75 -48.151 7.068 -24.512 1.00108.07 C ATOM 510 CE1 HIS A 75 -49.162 5.158 -24.133 1.00112.44 C ATOM 511 NE2 HIS A 75 -48.613 5.903 -25.076 1.00112.28 N ATOM 512 N GLY A 76 -46.371 9.037 -19.377 1.00 94.59 N ATOM 513 CA GLY A 76 -45.757 10.093 -18.578 1.00 92.59 C ATOM 514 C GLY A 76 -44.246 9.940 -18.590 1.00 92.45 C ATOM 515 O GLY A 76 -43.509 10.915 -18.769 1.00 91.96 O ATOM 516 N CYS A 77 -43.794 8.701 -18.413 1.00 89.95 N ATOM 517 CA CYS A 77 -42.375 8.369 -18.422 1.00 86.93 C ATOM 518 C CYS A 77 -41.710 8.700 -19.760 1.00 84.60 C ATOM 519 O CYS A 77 -40.581 9.188 -19.785 1.00 83.08 O ATOM 520 CB CYS A 77 -42.180 6.893 -18.078 1.00 90.65 C ATOM 521 SG CYS A 77 -40.459 6.397 -17.903 1.00101.76 S ATOM 522 N LEU A 78 -42.417 8.440 -20.861 1.00 84.01 N ATOM 523 CA LEU A 78 -41.909 8.720 -22.209 1.00 80.60 C ATOM 524 C LEU A 78 -41.719 10.217 -22.463 1.00 82.05 C ATOM 525 O LEU A 78 -40.769 10.621 -23.138 1.00 81.56 O ATOM 526 CB LEU A 78 -42.826 8.117 -23.283 1.00 75.87 C ATOM 527 CG LEU A 78 -42.366 8.285 -24.738 1.00 73.26 C ATOM 528 CD1 LEU A 78 -41.282 7.285 -25.103 1.00 69.40 C ATOM 529 CD2 LEU A 78 -43.537 8.209 -25.703 1.00 72.07 C ATOM 530 N PHE A 79 -42.623 11.030 -21.921 1.00 85.34 N ATOM 531 CA PHE A 79 -42.567 12.484 -22.083 1.00 86.33 C ATOM 532 C PHE A 79 -41.305 13.071 -21.443 1.00 85.83 C ATOM 533 O PHE A 79 -40.683 13.978 -22.001 1.00 84.78 O ATOM 534 CB PHE A 79 -43.830 13.136 -21.510 1.00 88.42 C ATOM 535 CG PHE A 79 -44.029 14.566 -21.937 1.00 91.44 C ATOM 536 CD1 PHE A 79 -44.662 14.866 -23.142 1.00 92.95 C ATOM 537 CD2 PHE A 79 -43.602 15.615 -21.126 1.00 94.57 C ATOM 538 CE1 PHE A 79 -44.853 16.190 -23.545 1.00 93.32 C ATOM 539 CE2 PHE A 79 -43.789 16.943 -21.517 1.00 97.10 C ATOM 540 CZ PHE A 79 -44.418 17.229 -22.731 1.00 95.87 C ATOM 541 N ILE A 80 -40.929 12.538 -20.283 1.00 83.95 N ATOM 542 CA ILE A 80 -39.704 12.948 -19.593 1.00 85.33 C ATOM 543 C ILE A 80 -38.454 12.592 -20.417 1.00 85.13 C ATOM 544 O ILE A 80 -37.552 13.420 -20.580 1.00 84.60 O ATOM 545 CB ILE A 80 -39.617 12.322 -18.174 1.00 86.08 C ATOM 546 CG1 ILE A 80 -40.898 12.610 -17.383 1.00 88.14 C ATOM 547 CG2 ILE A 80 -38.398 12.841 -17.418 1.00 83.68 C ATOM 548 CD1 ILE A 80 -41.186 11.607 -16.270 1.00 89.84 C ATOM 549 N ALA A 81 -38.416 11.366 -20.940 1.00 82.17 N ATOM 550 CA ALA A 81 -37.294 10.901 -21.750 1.00 79.21 C ATOM 551 C ALA A 81 -37.175 11.695 -23.051 1.00 80.56 C ATOM 552 O ALA A 81 -36.070 12.053 -23.467 1.00 80.14 O ATOM 553 CB ALA A 81 -37.421 9.421 -22.032 1.00 75.43 C ATOM 554 N CYS A 82 -38.317 11.982 -23.674 1.00 80.90 N ATOM 555 CA CYS A 82 -38.357 12.778 -24.900 1.00 79.75 C ATOM 556 C CYS A 82 -37.888 14.203 -24.661 1.00 79.11 C ATOM 557 O CYS A 82 -37.242 14.800 -25.525 1.00 78.32 O ATOM 558 CB CYS A 82 -39.759 12.782 -25.497 1.00 79.81 C ATOM 559 SG CYS A 82 -40.184 11.257 -26.361 1.00 87.36 S ATOM 560 N PHE A 83 -38.208 14.738 -23.484 1.00 80.43 N ATOM 561 CA PHE A 83 -37.773 16.078 -23.098 1.00 79.38 C ATOM 562 C PHE A 83 -36.251 16.145 -22.948 1.00 75.01 C ATOM 563 O PHE A 83 -35.624 17.117 -23.378 1.00 75.15 O ATOM 564 CB PHE A 83 -38.479 16.537 -21.820 1.00 84.73 C ATOM 565 CG PHE A 83 -38.889 17.986 -21.843 1.00 95.28 C ATOM 566 CD1 PHE A 83 -39.841 18.442 -22.761 1.00 99.13 C ATOM 567 CD2 PHE A 83 -38.329 18.899 -20.950 1.00 98.35 C ATOM 568 CE1 PHE A 83 -40.224 19.786 -22.792 1.00100.57 C ATOM 569 CE2 PHE A 83 -38.706 20.245 -20.968 1.00100.48 C ATOM 570 CZ PHE A 83 -39.656 20.689 -21.892 1.00102.24 C ATOM 571 N VAL A 84 -35.665 15.100 -22.364 1.00 69.01 N ATOM 572 CA VAL A 84 -34.208 14.959 -22.293 1.00 64.79 C ATOM 573 C VAL A 84 -33.606 14.912 -23.704 1.00 62.77 C ATOM 574 O VAL A 84 -32.666 15.649 -24.004 1.00 62.89 O ATOM 575 CB VAL A 84 -33.787 13.707 -21.465 1.00 65.42 C ATOM 576 CG1 VAL A 84 -32.291 13.438 -21.583 1.00 64.90 C ATOM 577 CG2 VAL A 84 -34.171 13.873 -20.005 1.00 63.76 C ATOM 578 N LEU A 85 -34.170 14.062 -24.565 1.00 58.86 N ATOM 579 CA LEU A 85 -33.726 13.932 -25.953 1.00 55.47 C ATOM 580 C LEU A 85 -33.784 15.262 -26.717 1.00 56.57 C ATOM 581 O LEU A 85 -32.877 15.574 -27.492 1.00 55.66 O ATOM 582 CB LEU A 85 -34.543 12.856 -26.683 1.00 54.28 C ATOM 583 CG LEU A 85 -34.425 11.390 -26.234 1.00 52.21 C ATOM 584 CD1 LEU A 85 -35.642 10.600 -26.665 1.00 50.93 C ATOM 585 CD2 LEU A 85 -33.157 10.720 -26.737 1.00 50.91 C ATOM 586 N VAL A 86 -34.839 16.043 -26.484 1.00 57.16 N ATOM 587 CA VAL A 86 -35.003 17.352 -27.128 1.00 60.44 C ATOM 588 C VAL A 86 -33.907 18.356 -26.739 1.00 64.86 C ATOM 589 O VAL A 86 -33.289 18.976 -27.614 1.00 65.16 O ATOM 590 CB VAL A 86 -36.389 17.970 -26.820 1.00 59.92 C ATOM 591 CG1 VAL A 86 -36.477 19.409 -27.343 1.00 59.22 C ATOM 592 CG2 VAL A 86 -37.498 17.128 -27.414 1.00 60.26 C ATOM 593 N LEU A 87 -33.684 18.514 -25.432 1.00 67.97 N ATOM 594 CA LEU A 87 -32.750 19.517 -24.901 1.00 69.97 C ATOM 595 C LEU A 87 -31.287 19.178 -25.173 1.00 73.28 C ATOM 596 O LEU A 87 -30.478 20.077 -25.431 1.00 74.59 O ATOM 597 CB LEU A 87 -32.962 19.726 -23.399 1.00 70.74 C ATOM 598 CG LEU A 87 -34.338 20.174 -22.897 1.00 70.46 C ATOM 599 CD1 LEU A 87 -34.379 20.112 -21.378 1.00 66.79 C ATOM 600 CD2 LEU A 87 -34.706 21.568 -23.404 1.00 71.55 C ATOM 601 N THR A 88 -30.947 17.891 -25.106 1.00 72.69 N ATOM 602 CA THR A 88 -29.613 17.437 -25.497 1.00 74.48 C ATOM 603 C THR A 88 -29.386 17.676 -26.993 1.00 74.47 C ATOM 604 O THR A 88 -28.289 18.060 -27.401 1.00 73.91 O ATOM 605 CB THR A 88 -29.357 15.950 -25.155 1.00 75.61 C ATOM 606 OG1 THR A 88 -30.368 15.130 -25.751 1.00 83.76 O ATOM 607 CG2 THR A 88 -29.352 15.730 -23.652 1.00 74.83 C ATOM 608 N ALA A 89 -30.430 17.465 -27.796 1.00 72.34 N ATOM 609 CA ALA A 89 -30.365 17.709 -29.237 1.00 70.19 C ATOM 610 C ALA A 89 -30.152 19.184 -29.544 1.00 70.10 C ATOM 611 O ALA A 89 -29.344 19.526 -30.411 1.00 69.51 O ATOM 612 CB ALA A 89 -31.612 17.200 -29.927 1.00 69.93 C ATOM 613 N SER A 90 -30.872 20.046 -28.825 1.00 69.93 N ATOM 614 CA SER A 90 -30.730 21.498 -28.961 1.00 69.18 C ATOM 615 C SER A 90 -29.305 21.948 -28.652 1.00 68.98 C ATOM 616 O SER A 90 -28.756 22.795 -29.354 1.00 67.68 O ATOM 617 CB SER A 90 -31.727 22.226 -28.057 1.00 69.67 C ATOM 618 OG SER A 90 -31.418 22.034 -26.685 1.00 69.30 O ATOM 619 N SER A 91 -28.719 21.362 -27.606 1.00 69.07 N ATOM 620 CA SER A 91 -27.321 21.601 -27.234 1.00 69.13 C ATOM 621 C SER A 91 -26.361 21.288 -28.382 1.00 67.19 C ATOM 622 O SER A 91 -25.471 22.080 -28.684 1.00 67.43 O ATOM 623 CB SER A 91 -26.957 20.779 -25.994 1.00 70.57 C ATOM 624 OG SER A 91 -25.554 20.631 -25.860 1.00 72.21 O ATOM 625 N ILE A 92 -26.562 20.136 -29.018 1.00 66.78 N ATOM 626 CA ILE A 92 -25.738 19.691 -30.142 1.00 63.56 C ATOM 627 C ILE A 92 -25.867 20.587 -31.379 1.00 61.97 C ATOM 628 O ILE A 92 -24.860 20.942 -31.985 1.00 61.36 O ATOM 629 CB ILE A 92 -26.064 18.234 -30.532 1.00 64.64 C ATOM 630 CG1 ILE A 92 -25.676 17.274 -29.404 1.00 66.97 C ATOM 631 CG2 ILE A 92 -25.351 17.854 -31.822 1.00 66.97 C ATOM 632 CD1 ILE A 92 -26.316 15.891 -29.519 1.00 69.86 C ATOM 633 N PHE A 93 -27.096 20.943 -31.755 1.00 60.41 N ATOM 634 CA PHE A 93 -27.327 21.693 -32.995 1.00 60.10 C ATOM 635 C PHE A 93 -26.887 23.140 -32.902 1.00 61.59 C ATOM 636 O PHE A 93 -26.265 23.665 -33.824 1.00 62.34 O ATOM 637 CB PHE A 93 -28.789 21.620 -33.436 1.00 59.32 C ATOM 638 CG PHE A 93 -29.211 20.267 -33.917 1.00 57.06 C ATOM 639 CD1 PHE A 93 -28.531 19.637 -34.953 1.00 57.42 C ATOM 640 CD2 PHE A 93 -30.291 19.619 -33.333 1.00 57.60 C ATOM 641 CE1 PHE A 93 -28.922 18.377 -35.399 1.00 59.05 C ATOM 642 CE2 PHE A 93 -30.691 18.360 -33.772 1.00 58.59 C ATOM 643 CZ PHE A 93 -30.003 17.736 -34.804 1.00 58.03 C ATOM 644 N SER A 94 -27.219 23.788 -31.789 1.00 65.19 N ATOM 645 CA SER A 94 -26.752 25.150 -31.523 1.00 66.66 C ATOM 646 C SER A 94 -25.220 25.213 -31.534 1.00 65.84 C ATOM 647 O SER A 94 -24.636 26.216 -31.947 1.00 66.27 O ATOM 648 CB SER A 94 -27.307 25.655 -30.196 1.00 64.41 C ATOM 649 OG SER A 94 -27.026 24.727 -29.162 1.00 64.16 O ATOM 650 N LEU A 95 -24.584 24.128 -31.095 1.00 65.19 N ATOM 651 CA LEU A 95 -23.135 23.977 -31.192 1.00 66.14 C ATOM 652 C LEU A 95 -22.683 23.852 -32.647 1.00 66.44 C ATOM 653 O LEU A 95 -21.681 24.451 -33.037 1.00 70.13 O ATOM 654 CB LEU A 95 -22.667 22.772 -30.372 1.00 67.03 C ATOM 655 CG LEU A 95 -21.181 22.404 -30.359 1.00 70.03 C ATOM 656 CD1 LEU A 95 -20.334 23.517 -29.763 1.00 72.24 C ATOM 657 CD2 LEU A 95 -20.978 21.109 -29.588 1.00 73.67 C ATOM 658 N LEU A 96 -23.428 23.080 -33.439 1.00 65.01 N ATOM 659 CA LEU A 96 -23.166 22.918 -34.872 1.00 64.05 C ATOM 660 C LEU A 96 -23.266 24.249 -35.623 1.00 66.32 C ATOM 661 O LEU A 96 -22.485 24.513 -36.541 1.00 66.70 O ATOM 662 CB LEU A 96 -24.130 21.892 -35.478 1.00 62.57 C ATOM 663 CG LEU A 96 -24.143 21.629 -36.990 1.00 61.78 C ATOM 664 CD1 LEU A 96 -22.884 20.905 -37.457 1.00 62.21 C ATOM 665 CD2 LEU A 96 -25.373 20.823 -37.364 1.00 62.41 C ATOM 666 N ALA A 97 -24.228 25.081 -35.226 1.00 66.83 N ATOM 667 CA ALA A 97 -24.375 26.420 -35.788 1.00 67.95 C ATOM 668 C ALA A 97 -23.061 27.195 -35.693 1.00 70.38 C ATOM 669 O ALA A 97 -22.627 27.801 -36.673 1.00 71.68 O ATOM 670 CB ALA A 97 -25.494 27.171 -35.084 1.00 68.75 C ATOM 671 N ILE A 98 -22.430 27.155 -34.517 1.00 71.63 N ATOM 672 CA ILE A 98 -21.130 27.794 -34.297 1.00 71.37 C ATOM 673 C ILE A 98 -20.110 27.332 -35.342 1.00 74.84 C ATOM 674 O ILE A 98 -19.446 28.157 -35.972 1.00 77.80 O ATOM 675 CB ILE A 98 -20.598 27.540 -32.868 1.00 67.73 C ATOM 676 CG1 ILE A 98 -21.570 28.117 -31.834 1.00 67.60 C ATOM 677 CG2 ILE A 98 -19.208 28.148 -32.694 1.00 65.87 C ATOM 678 CD1 ILE A 98 -21.261 27.736 -30.393 1.00 67.61 C ATOM 679 N ALA A 99 -20.016 26.019 -35.535 1.00 74.75 N ATOM 680 CA ALA A 99 -19.109 25.435 -36.522 1.00 77.10 C ATOM 681 C ALA A 99 -19.392 25.898 -37.954 1.00 78.32 C ATOM 682 O ALA A 99 -18.460 26.171 -38.712 1.00 79.48 O ATOM 683 CB ALA A 99 -19.142 23.920 -36.440 1.00 77.88 C ATOM 684 N ILE A 100 -20.670 25.983 -38.319 1.00 79.67 N ATOM 685 CA ILE A 100 -21.061 26.405 -39.670 1.00 81.53 C ATOM 686 C ILE A 100 -20.781 27.894 -39.882 1.00 83.01 C ATOM 687 O ILE A 100 -20.442 28.317 -40.990 1.00 84.27 O ATOM 688 CB ILE A 100 -22.549 26.092 -39.973 1.00 80.20 C ATOM 689 CG1 ILE A 100 -22.821 24.593 -39.841 1.00 79.04 C ATOM 690 CG2 ILE A 100 -22.927 26.556 -41.376 1.00 80.92 C ATOM 691 CD1 ILE A 100 -24.288 24.247 -39.675 1.00 80.11 C ATOM 692 N ASP A 101 -20.922 28.675 -38.813 1.00 84.13 N ATOM 693 CA ASP A 101 -20.632 30.103 -38.850 1.00 86.41 C ATOM 694 C ASP A 101 -19.155 30.335 -39.151 1.00 87.00 C ATOM 695 O ASP A 101 -18.811 31.059 -40.089 1.00 89.23 O ATOM 696 CB ASP A 101 -21.012 30.759 -37.524 1.00 89.03 C ATOM 697 CG ASP A 101 -20.487 32.172 -37.405 1.00 92.70 C ATOM 698 OD1 ASP A 101 -20.971 33.055 -38.147 1.00 94.39 O ATOM 699 OD2 ASP A 101 -19.585 32.395 -36.572 1.00 94.05 O1- ATOM 700 N ARG A 102 -18.295 29.701 -38.353 1.00 86.58 N ATOM 701 CA ARG A 102 -16.846 29.762 -38.533 1.00 87.62 C ATOM 702 C ARG A 102 -16.426 29.325 -39.929 1.00 89.59 C ATOM 703 O ARG A 102 -15.489 29.884 -40.498 1.00 93.24 O ATOM 704 CB ARG A 102 -16.128 28.910 -37.481 1.00 87.25 C ATOM 705 CG ARG A 102 -16.373 29.330 -36.028 1.00 91.18 C ATOM 706 CD ARG A 102 -15.725 30.669 -35.691 1.00 94.32 C ATOM 707 NE ARG A 102 -16.434 31.798 -36.293 1.00 95.44 N ATOM 708 CZ ARG A 102 -15.934 33.023 -36.418 1.00 96.31 C ATOM 709 NH1 ARG A 102 -14.711 33.299 -35.979 1.00 97.62 N ATOM 710 NH2 ARG A 102 -16.658 33.978 -36.984 1.00 98.20 N ATOM 711 N TYR A 103 -17.128 28.334 -40.474 1.00 88.89 N ATOM 712 CA TYR A 103 -16.872 27.863 -41.827 1.00 90.78 C ATOM 713 C TYR A 103 -17.071 28.976 -42.853 1.00 92.91 C ATOM 714 O TYR A 103 -16.225 29.176 -43.725 1.00 95.46 O ATOM 715 CB TYR A 103 -17.761 26.669 -42.167 1.00 91.07 C ATOM 716 CG TYR A 103 -17.523 26.137 -43.558 1.00 94.70 C ATOM 717 CD1 TYR A 103 -16.499 25.230 -43.807 1.00 96.35 C ATOM 718 CD2 TYR A 103 -18.311 26.553 -44.631 1.00 96.90 C ATOM 719 CE1 TYR A 103 -16.269 24.741 -45.084 1.00101.32 C ATOM 720 CE2 TYR A 103 -18.089 26.070 -45.914 1.00100.52 C ATOM 721 CZ TYR A 103 -17.065 25.165 -46.132 1.00101.84 C ATOM 722 OH TYR A 103 -16.832 24.676 -47.396 1.00109.80 O ATOM 723 N ILE A 104 -18.192 29.688 -42.746 1.00 94.03 N ATOM 724 CA ILE A 104 -18.477 30.819 -43.627 1.00 95.39 C ATOM 725 C ILE A 104 -17.448 31.921 -43.383 1.00 97.82 C ATOM 726 O ILE A 104 -16.885 32.479 -44.328 1.00 94.85 O ATOM 727 CB ILE A 104 -19.910 31.371 -43.421 1.00 92.64 C ATOM 728 CG1 ILE A 104 -20.946 30.266 -43.648 1.00 91.86 C ATOM 729 CG2 ILE A 104 -20.176 32.546 -44.366 1.00 93.47 C ATOM 730 CD1 ILE A 104 -22.302 30.549 -43.037 1.00 91.40 C ATOM 731 N ALA A 105 -17.194 32.198 -42.105 1.00 98.56 N ATOM 732 CA ALA A 105 -16.247 33.226 -41.686 1.00101.71 C ATOM 733 C ALA A 105 -14.821 32.984 -42.188 1.00106.88 C ATOM 734 O ALA A 105 -14.045 33.930 -42.327 1.00114.15 O ATOM 735 CB ALA A 105 -16.259 33.362 -40.173 1.00 98.72 C ATOM 736 N ILE A 106 -14.481 31.723 -42.451 1.00106.16 N ATOM 737 CA ILE A 106 -13.152 31.378 -42.955 1.00107.14 C ATOM 738 C ILE A 106 -13.120 31.252 -44.480 1.00112.22 C ATOM 739 O ILE A 106 -12.239 31.819 -45.126 1.00118.87 O ATOM 740 CB ILE A 106 -12.552 30.124 -42.239 1.00106.07 C ATOM 741 CG1 ILE A 106 -11.627 30.547 -41.086 1.00105.54 C ATOM 742 CG2 ILE A 106 -11.763 29.240 -43.205 1.00102.64 C ATOM 743 CD1 ILE A 106 -12.334 31.006 -39.810 1.00100.76 C ATOM 744 N ARG A 107 -14.082 30.530 -45.051 1.00114.32 N ATOM 745 CA ARG A 107 -14.082 30.271 -46.492 1.00117.94 C ATOM 746 C ARG A 107 -14.528 31.474 -47.326 1.00118.43 C ATOM 747 O ARG A 107 -13.949 31.749 -48.378 1.00120.04 O ATOM 748 CB ARG A 107 -14.912 29.028 -46.833 1.00123.63 C ATOM 749 CG ARG A 107 -14.386 27.730 -46.210 1.00130.99 C ATOM 750 CD ARG A 107 -12.988 27.355 -46.711 1.00134.51 C ATOM 751 NE ARG A 107 -13.009 26.850 -48.083 1.00137.45 N ATOM 752 CZ ARG A 107 -11.937 26.445 -48.759 1.00135.14 C ATOM 753 NH1 ARG A 107 -10.733 26.481 -48.201 1.00134.17 N ATOM 754 NH2 ARG A 107 -12.072 26.004 -50.002 1.00134.11 N ATOM 755 N ILE A 108 -15.554 32.183 -46.857 1.00117.57 N ATOM 756 CA ILE A 108 -16.053 33.378 -47.543 1.00113.79 C ATOM 757 C ILE A 108 -16.190 34.528 -46.530 1.00115.27 C ATOM 758 O ILE A 108 -17.300 34.835 -46.082 1.00118.82 O ATOM 759 CB ILE A 108 -17.399 33.100 -48.276 1.00114.61 C ATOM 760 CG1 ILE A 108 -17.321 31.797 -49.085 1.00116.43 C ATOM 761 CG2 ILE A 108 -17.777 34.274 -49.187 1.00115.31 C ATOM 762 CD1 ILE A 108 -18.647 31.074 -49.248 1.00116.79 C ATOM 763 N PRO A 109 -15.056 35.163 -46.157 1.00113.29 N ATOM 764 CA PRO A 109 -15.037 36.150 -45.071 1.00111.47 C ATOM 765 C PRO A 109 -15.481 37.550 -45.489 1.00113.10 C ATOM 766 O PRO A 109 -15.769 38.387 -44.626 1.00111.01 O ATOM 767 CB PRO A 109 -13.560 36.179 -44.641 1.00107.06 C ATOM 768 CG PRO A 109 -12.829 35.228 -45.562 1.00106.01 C ATOM 769 CD PRO A 109 -13.715 34.988 -46.736 1.00110.21 C ATOM 770 N LEU A 110 -15.529 37.797 -46.797 1.00115.47 N ATOM 771 CA LEU A 110 -15.896 39.108 -47.331 1.00120.51 C ATOM 772 C LEU A 110 -17.402 39.357 -47.238 1.00122.92 C ATOM 773 O LEU A 110 -17.839 40.301 -46.574 1.00124.76 O ATOM 774 CB LEU A 110 -15.402 39.265 -48.776 1.00123.62 C ATOM 775 CG LEU A 110 -13.889 39.248 -49.036 1.00124.14 C ATOM 776 CD1 LEU A 110 -13.598 38.921 -50.497 1.00123.73 C ATOM 777 CD2 LEU A 110 -13.219 40.562 -48.626 1.00120.03 C ATOM 778 N ARG A 111 -18.191 38.503 -47.890 1.00122.82 N ATOM 779 CA ARG A 111 -19.649 38.630 -47.859 1.00120.82 C ATOM 780 C ARG A 111 -20.277 38.061 -46.584 1.00115.46 C ATOM 781 O ARG A 111 -21.488 38.160 -46.394 1.00114.28 O ATOM 782 CB ARG A 111 -20.288 38.013 -49.109 1.00125.37 C ATOM 783 CG ARG A 111 -20.183 38.892 -50.355 1.00128.50 C ATOM 784 CD ARG A 111 -21.391 38.732 -51.277 1.00126.86 C ATOM 785 NE ARG A 111 -21.453 37.414 -51.910 1.00125.80 N ATOM 786 CZ ARG A 111 -20.891 37.105 -53.077 1.00126.16 C ATOM 787 NH1 ARG A 111 -20.208 38.014 -53.763 1.00126.46 N ATOM 788 NH2 ARG A 111 -21.011 35.877 -53.562 1.00127.64 N ATOM 789 N TYR A 112 -19.445 37.481 -45.717 1.00110.80 N ATOM 790 CA TYR A 112 -19.876 36.979 -44.409 1.00108.84 C ATOM 791 C TYR A 112 -20.666 38.021 -43.623 1.00109.77 C ATOM 792 O TYR A 112 -21.695 37.710 -43.020 1.00113.50 O ATOM 793 CB TYR A 112 -18.668 36.529 -43.578 1.00103.77 C ATOM 794 CG TYR A 112 -18.991 36.270 -42.121 1.00100.61 C ATOM 795 CD1 TYR A 112 -19.414 35.011 -41.697 1.00101.28 C ATOM 796 CD2 TYR A 112 -18.881 37.284 -41.166 1.00 98.71 C ATOM 797 CE1 TYR A 112 -19.716 34.764 -40.363 1.00 97.31 C ATOM 798 CE2 TYR A 112 -19.184 37.046 -39.828 1.00 98.38 C ATOM 799 CZ TYR A 112 -19.600 35.783 -39.437 1.00 96.68 C ATOM 800 OH TYR A 112 -19.902 35.538 -38.123 1.00 94.75 O ATOM 801 N ASN A 113 -20.165 39.253 -43.626 1.00109.55 N ATOM 802 CA ASN A 113 -20.789 40.351 -42.898 1.00110.76 C ATOM 803 C ASN A 113 -22.102 40.802 -43.536 1.00110.52 C ATOM 804 O ASN A 113 -22.912 41.473 -42.894 1.00111.71 O ATOM 805 CB ASN A 113 -19.809 41.519 -42.765 1.00109.69 C ATOM 806 CG ASN A 113 -18.494 41.106 -42.118 1.00109.80 C ATOM 807 OD1 ASN A 113 -17.485 40.920 -42.799 1.00107.83 O ATOM 808 ND2 ASN A 113 -18.507 40.943 -40.799 1.00109.31 N ATOM 809 N GLY A 114 -22.306 40.418 -44.796 1.00111.41 N ATOM 810 CA GLY A 114 -23.546 40.704 -45.520 1.00111.74 C ATOM 811 C GLY A 114 -24.440 39.489 -45.720 1.00109.46 C ATOM 812 O GLY A 114 -25.558 39.614 -46.225 1.00108.96 O ATOM 813 N LEU A 115 -23.944 38.316 -45.327 1.00107.02 N ATOM 814 CA LEU A 115 -24.696 37.064 -45.424 1.00102.39 C ATOM 815 C LEU A 115 -25.193 36.624 -44.045 1.00 97.75 C ATOM 816 O LEU A 115 -26.382 36.366 -43.860 1.00 97.49 O ATOM 817 CB LEU A 115 -23.834 35.964 -46.059 1.00102.06 C ATOM 818 CG LEU A 115 -24.521 34.827 -46.822 1.00100.79 C ATOM 819 CD1 LEU A 115 -24.942 35.279 -48.217 1.00 99.94 C ATOM 820 CD2 LEU A 115 -23.602 33.624 -46.918 1.00 97.35 C ATOM 821 N VAL A 116 -24.278 36.546 -43.084 1.00 93.64 N ATOM 822 CA VAL A 116 -24.619 36.158 -41.720 1.00 92.60 C ATOM 823 C VAL A 116 -25.008 37.398 -40.915 1.00 96.22 C ATOM 824 O VAL A 116 -24.176 38.000 -40.229 1.00 99.62 O ATOM 825 CB VAL A 116 -23.462 35.394 -41.032 1.00 91.21 C ATOM 826 CG1 VAL A 116 -23.919 34.808 -39.700 1.00 91.87 C ATOM 827 CG2 VAL A 116 -22.943 34.288 -41.939 1.00 91.44 C ATOM 828 N THR A 117 -26.281 37.775 -41.023 1.00 97.57 N ATOM 829 CA THR A 117 -26.827 38.939 -40.322 1.00 96.18 C ATOM 830 C THR A 117 -27.603 38.538 -39.069 1.00 96.22 C ATOM 831 O THR A 117 -27.967 37.376 -38.904 1.00 96.20 O ATOM 832 CB THR A 117 -27.740 39.773 -41.239 1.00 94.13 C ATOM 833 OG1 THR A 117 -28.492 38.897 -42.088 1.00 94.89 O ATOM 834 CG2 THR A 117 -26.912 40.713 -42.100 1.00 95.83 C ATOM 835 N GLY A 118 -27.852 39.513 -38.197 1.00 98.15 N ATOM 836 CA GLY A 118 -28.558 39.291 -36.935 1.00 97.50 C ATOM 837 C GLY A 118 -29.938 38.674 -37.071 1.00 98.18 C ATOM 838 O GLY A 118 -30.373 37.928 -36.193 1.00100.95 O ATOM 839 N THR A 119 -30.629 38.992 -38.165 1.00 96.22 N ATOM 840 CA THR A 119 -31.932 38.391 -38.466 1.00 95.99 C ATOM 841 C THR A 119 -31.771 36.925 -38.878 1.00 95.38 C ATOM 842 O THR A 119 -32.326 36.032 -38.236 1.00 95.80 O ATOM 843 CB THR A 119 -32.711 39.213 -39.529 1.00 96.08 C ATOM 844 OG1 THR A 119 -33.361 40.311 -38.881 1.00 98.75 O ATOM 845 CG2 THR A 119 -33.770 38.371 -40.240 1.00 93.68 C ATOM 846 N ARG A 120 -30.994 36.686 -39.932 1.00 92.25 N ATOM 847 CA ARG A 120 -30.710 35.330 -40.396 1.00 88.83 C ATOM 848 C ARG A 120 -30.112 34.436 -39.306 1.00 87.14 C ATOM 849 O ARG A 120 -30.366 33.231 -39.285 1.00 86.90 O ATOM 850 CB ARG A 120 -29.817 35.361 -41.637 1.00 86.85 C ATOM 851 CG ARG A 120 -30.607 35.377 -42.932 1.00 88.47 C ATOM 852 CD ARG A 120 -29.716 35.472 -44.156 1.00 90.16 C ATOM 853 NE ARG A 120 -29.652 36.834 -44.681 1.00 93.24 N ATOM 854 CZ ARG A 120 -29.218 37.153 -45.898 1.00 95.63 C ATOM 855 NH1 ARG A 120 -28.802 36.210 -46.736 1.00 94.87 N ATOM 856 NH2 ARG A 120 -29.203 38.422 -46.282 1.00100.63 N ATOM 857 N ALA A 121 -29.337 35.032 -38.402 1.00 86.50 N ATOM 858 CA ALA A 121 -28.764 34.312 -37.261 1.00 89.44 C ATOM 859 C ALA A 121 -29.849 33.716 -36.373 1.00 88.36 C ATOM 860 O ALA A 121 -29.711 32.590 -35.899 1.00 88.74 O ATOM 861 CB ALA A 121 -27.852 35.222 -36.443 1.00 91.89 C ATOM 862 N LYS A 122 -30.923 34.476 -36.160 1.00 87.44 N ATOM 863 CA LYS A 122 -32.073 34.016 -35.378 1.00 87.49 C ATOM 864 C LYS A 122 -32.883 32.970 -36.148 1.00 84.53 C ATOM 865 O LYS A 122 -33.525 32.106 -35.550 1.00 79.35 O ATOM 866 CB LYS A 122 -32.971 35.191 -34.983 1.00 88.66 C ATOM 867 CG LYS A 122 -32.322 36.217 -34.065 1.00 90.19 C ATOM 868 CD LYS A 122 -33.258 37.392 -33.844 1.00 92.33 C ATOM 869 CE LYS A 122 -32.616 38.475 -33.002 1.00 94.81 C ATOM 870 NZ LYS A 122 -33.489 39.680 -32.938 1.00 99.48 N ATOM 871 N GLY A 123 -32.851 33.066 -37.476 1.00 84.78 N ATOM 872 CA GLY A 123 -33.439 32.055 -38.348 1.00 83.96 C ATOM 873 C GLY A 123 -32.765 30.709 -38.151 1.00 85.41 C ATOM 874 O GLY A 123 -33.440 29.683 -38.035 1.00 90.72 O ATOM 875 N ILE A 124 -31.434 30.715 -38.097 1.00 78.46 N ATOM 876 CA ILE A 124 -30.661 29.492 -37.886 1.00 75.17 C ATOM 877 C ILE A 124 -30.881 28.898 -36.485 1.00 75.90 C ATOM 878 O ILE A 124 -30.938 27.675 -36.336 1.00 76.69 O ATOM 879 CB ILE A 124 -29.147 29.695 -38.227 1.00 74.00 C ATOM 880 CG1 ILE A 124 -28.879 29.369 -39.699 1.00 71.45 C ATOM 881 CG2 ILE A 124 -28.243 28.814 -37.372 1.00 73.10 C ATOM 882 CD1 ILE A 124 -29.072 30.531 -40.648 1.00 71.96 C ATOM 883 N ILE A 125 -31.024 29.754 -35.473 1.00 73.56 N ATOM 884 CA ILE A 125 -31.304 29.286 -34.110 1.00 75.47 C ATOM 885 C ILE A 125 -32.683 28.625 -34.036 1.00 77.35 C ATOM 886 O ILE A 125 -32.866 27.631 -33.323 1.00 77.23 O ATOM 887 CB ILE A 125 -31.222 30.422 -33.063 1.00 77.82 C ATOM 888 CG1 ILE A 125 -29.893 31.172 -33.176 1.00 79.22 C ATOM 889 CG2 ILE A 125 -31.399 29.864 -31.640 1.00 76.12 C ATOM 890 CD1 ILE A 125 -29.943 32.599 -32.650 1.00 80.22 C ATOM 891 N ALA A 126 -33.643 29.188 -34.773 1.00 77.97 N ATOM 892 CA ALA A 126 -34.989 28.623 -34.887 1.00 75.17 C ATOM 893 C ALA A 126 -34.913 27.195 -35.419 1.00 73.67 C ATOM 894 O ALA A 126 -35.398 26.260 -34.774 1.00 73.72 O ATOM 895 CB ALA A 126 -35.863 29.487 -35.790 1.00 72.45 C ATOM 896 N ILE A 127 -34.279 27.042 -36.581 1.00 67.62 N ATOM 897 CA ILE A 127 -34.030 25.735 -37.193 1.00 66.68 C ATOM 898 C ILE A 127 -33.440 24.726 -36.190 1.00 68.70 C ATOM 899 O ILE A 127 -33.875 23.575 -36.141 1.00 69.23 O ATOM 900 CB ILE A 127 -33.134 25.873 -38.457 1.00 63.43 C ATOM 901 CG1 ILE A 127 -33.897 26.609 -39.563 1.00 63.33 C ATOM 902 CG2 ILE A 127 -32.667 24.516 -38.959 1.00 58.63 C ATOM 903 CD1 ILE A 127 -33.017 27.366 -40.545 1.00 62.84 C ATOM 904 N CYS A 128 -32.475 25.165 -35.381 1.00 69.66 N ATOM 905 CA CYS A 128 -31.869 24.303 -34.363 1.00 72.51 C ATOM 906 C CYS A 128 -32.917 23.750 -33.409 1.00 73.36 C ATOM 907 O CYS A 128 -32.850 22.586 -33.005 1.00 71.29 O ATOM 908 CB CYS A 128 -30.807 25.059 -33.563 1.00 75.10 C ATOM 909 SG CYS A 128 -29.274 25.354 -34.454 1.00 78.46 S ATOM 910 N TRP A 129 -33.886 24.593 -33.066 1.00 73.52 N ATOM 911 CA TRP A 129 -34.932 24.230 -32.123 1.00 73.13 C ATOM 912 C TRP A 129 -36.098 23.480 -32.765 1.00 75.27 C ATOM 913 O TRP A 129 -36.730 22.647 -32.111 1.00 78.78 O ATOM 914 CB TRP A 129 -35.413 25.468 -31.375 1.00 70.97 C ATOM 915 CG TRP A 129 -34.508 25.820 -30.239 1.00 72.12 C ATOM 916 CD1 TRP A 129 -33.523 26.768 -30.232 1.00 71.46 C ATOM 917 CD2 TRP A 129 -34.485 25.207 -28.943 1.00 71.24 C ATOM 918 NE1 TRP A 129 -32.896 26.791 -29.006 1.00 71.57 N ATOM 919 CE2 TRP A 129 -33.468 25.844 -28.197 1.00 70.83 C ATOM 920 CE3 TRP A 129 -35.229 24.186 -28.339 1.00 69.89 C ATOM 921 CZ2 TRP A 129 -33.179 25.496 -26.876 1.00 71.54 C ATOM 922 CZ3 TRP A 129 -34.942 23.840 -27.025 1.00 71.20 C ATOM 923 CH2 TRP A 129 -33.925 24.494 -26.308 1.00 72.52 C ATOM 924 N VAL A 130 -36.379 23.764 -34.036 1.00 72.42 N ATOM 925 CA VAL A 130 -37.365 22.987 -34.788 1.00 70.02 C ATOM 926 C VAL A 130 -36.857 21.554 -34.922 1.00 71.16 C ATOM 927 O VAL A 130 -37.571 20.608 -34.584 1.00 74.20 O ATOM 928 CB VAL A 130 -37.683 23.606 -36.183 1.00 69.52 C ATOM 929 CG1 VAL A 130 -38.369 22.602 -37.091 1.00 67.81 C ATOM 930 CG2 VAL A 130 -38.556 24.839 -36.036 1.00 69.08 C ATOM 931 N LEU A 131 -35.613 21.408 -35.380 1.00 69.28 N ATOM 932 CA LEU A 131 -34.994 20.093 -35.561 1.00 69.41 C ATOM 933 C LEU A 131 -34.887 19.282 -34.269 1.00 69.87 C ATOM 934 O LEU A 131 -34.954 18.057 -34.305 1.00 70.75 O ATOM 935 CB LEU A 131 -33.613 20.221 -36.219 1.00 71.38 C ATOM 936 CG LEU A 131 -33.466 20.175 -37.750 1.00 73.64 C ATOM 937 CD1 LEU A 131 -33.850 18.812 -38.315 1.00 74.94 C ATOM 938 CD2 LEU A 131 -34.256 21.272 -38.452 1.00 77.79 C ATOM 939 N SER A 132 -34.732 19.964 -33.137 1.00 69.51 N ATOM 940 CA SER A 132 -34.610 19.295 -31.845 1.00 69.77 C ATOM 941 C SER A 132 -35.932 18.715 -31.366 1.00 70.85 C ATOM 942 O SER A 132 -35.963 17.610 -30.818 1.00 68.85 O ATOM 943 CB SER A 132 -34.054 20.251 -30.794 1.00 73.22 C ATOM 944 OG SER A 132 -32.750 20.671 -31.145 1.00 79.58 O ATOM 945 N PHE A 133 -37.015 19.467 -31.563 1.00 73.28 N ATOM 946 CA PHE A 133 -38.346 19.038 -31.129 1.00 74.58 C ATOM 947 C PHE A 133 -38.871 17.901 -31.998 1.00 74.54 C ATOM 948 O PHE A 133 -39.398 16.914 -31.482 1.00 74.93 O ATOM 949 CB PHE A 133 -39.338 20.209 -31.118 1.00 76.71 C ATOM 950 CG PHE A 133 -39.341 21.001 -29.833 1.00 80.30 C ATOM 951 CD1 PHE A 133 -39.701 20.404 -28.624 1.00 81.41 C ATOM 952 CD2 PHE A 133 -38.992 22.351 -29.831 1.00 81.95 C ATOM 953 CE1 PHE A 133 -39.705 21.141 -27.429 1.00 81.12 C ATOM 954 CE2 PHE A 133 -38.999 23.097 -28.642 1.00 82.51 C ATOM 955 CZ PHE A 133 -39.356 22.488 -27.441 1.00 80.47 C ATOM 956 N ALA A 134 -38.711 18.041 -33.313 1.00 71.73 N ATOM 957 CA ALA A 134 -39.094 17.001 -34.263 1.00 69.38 C ATOM 958 C ALA A 134 -38.432 15.661 -33.930 1.00 69.72 C ATOM 959 O ALA A 134 -39.096 14.625 -33.927 1.00 74.31 O ATOM 960 CB ALA A 134 -38.756 17.430 -35.687 1.00 66.75 C ATOM 961 N ILE A 135 -37.135 15.695 -33.626 1.00 67.28 N ATOM 962 CA ILE A 135 -36.354 14.484 -33.349 1.00 66.02 C ATOM 963 C ILE A 135 -36.655 13.858 -31.977 1.00 64.34 C ATOM 964 O ILE A 135 -36.879 12.652 -31.878 1.00 63.98 O ATOM 965 CB ILE A 135 -34.832 14.746 -33.520 1.00 66.24 C ATOM 966 CG1 ILE A 135 -34.503 14.928 -35.007 1.00 68.33 C ATOM 967 CG2 ILE A 135 -34.000 13.614 -32.911 1.00 64.79 C ATOM 968 CD1 ILE A 135 -33.131 15.511 -35.285 1.00 70.43 C ATOM 969 N GLY A 136 -36.664 14.682 -30.933 1.00 62.71 N ATOM 970 CA GLY A 136 -36.878 14.204 -29.575 1.00 59.41 C ATOM 971 C GLY A 136 -38.328 13.896 -29.279 1.00 61.16 C ATOM 972 O GLY A 136 -38.621 13.167 -28.339 1.00 62.22 O ATOM 973 N LEU A 137 -39.241 14.452 -30.071 1.00 64.69 N ATOM 974 CA LEU A 137 -40.672 14.167 -29.900 1.00 68.54 C ATOM 975 C LEU A 137 -41.201 13.088 -30.850 1.00 69.79 C ATOM 976 O LEU A 137 -42.384 12.745 -30.798 1.00 70.76 O ATOM 977 CB LEU A 137 -41.521 15.441 -30.013 1.00 67.23 C ATOM 978 CG LEU A 137 -41.396 16.510 -28.922 1.00 67.42 C ATOM 979 CD1 LEU A 137 -42.570 17.462 -29.029 1.00 67.85 C ATOM 980 CD2 LEU A 137 -41.328 15.902 -27.522 1.00 65.88 C ATOM 981 N THR A 138 -40.325 12.559 -31.704 1.00 67.55 N ATOM 982 CA THR A 138 -40.669 11.446 -32.591 1.00 68.59 C ATOM 983 C THR A 138 -41.219 10.224 -31.833 1.00 70.42 C ATOM 984 O THR A 138 -42.176 9.595 -32.302 1.00 69.69 O ATOM 985 CB THR A 138 -39.475 11.040 -33.494 1.00 68.65 C ATOM 986 OG1 THR A 138 -39.224 12.078 -34.446 1.00 69.54 O ATOM 987 CG2 THR A 138 -39.764 9.749 -34.251 1.00 66.29 C ATOM 988 N PRO A 139 -40.629 9.883 -30.665 1.00 70.31 N ATOM 989 CA PRO A 139 -41.189 8.741 -29.937 1.00 71.64 C ATOM 990 C PRO A 139 -42.615 8.974 -29.442 1.00 74.74 C ATOM 991 O PRO A 139 -43.389 8.020 -29.335 1.00 76.10 O ATOM 992 CB PRO A 139 -40.227 8.573 -28.761 1.00 69.79 C ATOM 993 CG PRO A 139 -38.942 9.137 -29.260 1.00 69.73 C ATOM 994 CD PRO A 139 -39.353 10.320 -30.071 1.00 68.48 C ATOM 995 N MET A 140 -42.958 10.232 -29.172 1.00 75.72 N ATOM 996 CA MET A 140 -44.288 10.595 -28.691 1.00 77.93 C ATOM 997 C MET A 140 -45.396 10.219 -29.663 1.00 77.92 C ATOM 998 O MET A 140 -46.513 9.904 -29.253 1.00 76.86 O ATOM 999 CB MET A 140 -44.363 12.093 -28.422 1.00 81.66 C ATOM 1000 CG MET A 140 -45.213 12.434 -27.223 1.00 86.10 C ATOM 1001 SD MET A 140 -44.376 11.884 -25.730 1.00 91.13 S ATOM 1002 CE MET A 140 -43.086 13.118 -25.655 1.00 90.62 C ATOM 1003 N LEU A 141 -45.072 10.260 -30.951 1.00 80.55 N ATOM 1004 CA LEU A 141 -46.028 9.978 -32.016 1.00 83.62 C ATOM 1005 C LEU A 141 -46.497 8.523 -32.055 1.00 84.25 C ATOM 1006 O LEU A 141 -47.570 8.229 -32.583 1.00 88.86 O ATOM 1007 CB LEU A 141 -45.442 10.372 -33.373 1.00 83.62 C ATOM 1008 CG LEU A 141 -45.074 11.842 -33.567 1.00 84.49 C ATOM 1009 CD1 LEU A 141 -44.602 12.063 -34.992 1.00 86.31 C ATOM 1010 CD2 LEU A 141 -46.246 12.761 -33.236 1.00 83.10 C ATOM 1011 N GLY A 142 -45.698 7.620 -31.496 1.00 79.65 N ATOM 1012 CA GLY A 142 -46.054 6.209 -31.466 1.00 74.37 C ATOM 1013 C GLY A 142 -44.840 5.313 -31.411 1.00 70.88 C ATOM 1014 O GLY A 142 -44.914 4.190 -30.917 1.00 71.12 O ATOM 1015 N TRP A 143 -43.717 5.816 -31.915 1.00 66.54 N ATOM 1016 CA TRP A 143 -42.465 5.074 -31.908 1.00 64.13 C ATOM 1017 C TRP A 143 -41.897 4.941 -30.475 1.00 66.12 C ATOM 1018 O TRP A 143 -40.828 5.469 -30.153 1.00 65.49 O ATOM 1019 CB TRP A 143 -41.463 5.750 -32.848 1.00 56.16 C ATOM 1020 CG TRP A 143 -40.373 4.850 -33.303 1.00 51.37 C ATOM 1021 CD1 TRP A 143 -40.190 3.549 -32.951 1.00 51.34 C ATOM 1022 CD2 TRP A 143 -39.287 5.188 -34.171 1.00 49.47 C ATOM 1023 NE1 TRP A 143 -39.066 3.045 -33.556 1.00 50.62 N ATOM 1024 CE2 TRP A 143 -38.489 4.031 -34.310 1.00 49.65 C ATOM 1025 CE3 TRP A 143 -38.911 6.354 -34.850 1.00 48.47 C ATOM 1026 CZ2 TRP A 143 -37.338 4.004 -35.105 1.00 49.20 C ATOM 1027 CZ3 TRP A 143 -37.764 6.331 -35.637 1.00 46.47 C ATOM 1028 CH2 TRP A 143 -36.992 5.163 -35.758 1.00 48.21 C ATOM 1029 N ASN A 144 -42.629 4.223 -29.625 1.00 67.11 N ATOM 1030 CA ASN A 144 -42.294 4.088 -28.213 1.00 68.09 C ATOM 1031 C ASN A 144 -42.717 2.739 -27.659 1.00 70.98 C ATOM 1032 O ASN A 144 -43.695 2.160 -28.127 1.00 76.52 O ATOM 1033 CB ASN A 144 -42.962 5.199 -27.412 1.00 68.41 C ATOM 1034 CG ASN A 144 -44.463 5.215 -27.575 1.00 69.23 C ATOM 1035 OD1 ASN A 144 -45.158 4.313 -27.113 1.00 72.73 O ATOM 1036 ND2 ASN A 144 -44.976 6.251 -28.223 1.00 71.18 N ATOM 1037 N ASN A 145 -42.003 2.258 -26.642 1.00 71.26 N ATOM 1038 CA ASN A 145 -42.254 0.931 -26.068 1.00 70.20 C ATOM 1039 C ASN A 145 -43.447 0.835 -25.113 1.00 74.23 C ATOM 1040 O ASN A 145 -43.560 -0.133 -24.360 1.00 74.93 O ATOM 1041 CB ASN A 145 -40.999 0.406 -25.373 1.00 68.21 C ATOM 1042 CG ASN A 145 -39.841 0.197 -26.328 1.00 72.08 C ATOM 1043 OD1 ASN A 145 -40.028 -0.163 -27.493 1.00 75.07 O ATOM 1044 ND2 ASN A 145 -38.629 0.414 -25.832 1.00 72.87 N ATOM 1045 N CYS A 146 -44.339 1.823 -25.154 1.00 79.95 N ATOM 1046 CA CYS A 146 -45.492 1.866 -24.249 1.00 87.03 C ATOM 1047 C CYS A 146 -46.596 0.849 -24.544 1.00 88.28 C ATOM 1048 O CYS A 146 -47.375 0.499 -23.654 1.00 88.68 O ATOM 1049 CB CYS A 146 -46.075 3.279 -24.178 1.00 95.10 C ATOM 1050 SG CYS A 146 -45.258 4.341 -22.963 1.00103.14 S ATOM 1051 N GLY A 147 -46.655 0.374 -25.786 1.00 91.90 N ATOM 1052 CA GLY A 147 -47.589 -0.683 -26.166 1.00 92.75 C ATOM 1053 C GLY A 147 -47.279 -2.009 -25.492 1.00 93.26 C ATOM 1054 O GLY A 147 -48.149 -2.878 -25.390 1.00 97.95 O ATOM 1055 N GLN A 148 -46.038 -2.158 -25.028 1.00 90.74 N ATOM 1056 CA GLN A 148 -45.560 -3.401 -24.421 1.00 91.67 C ATOM 1057 C GLN A 148 -44.967 -3.173 -23.020 1.00 90.95 C ATOM 1058 O GLN A 148 -43.759 -3.357 -22.822 1.00 86.20 O ATOM 1059 CB GLN A 148 -44.521 -4.071 -25.335 1.00 95.01 C ATOM 1060 CG GLN A 148 -45.070 -4.656 -26.641 1.00100.27 C ATOM 1061 CD GLN A 148 -45.590 -3.599 -27.607 1.00105.62 C ATOM 1062 OE1 GLN A 148 -45.073 -2.479 -27.665 1.00107.70 O ATOM 1063 NE2 GLN A 148 -46.626 -3.950 -28.363 1.00106.44 N ATOM 1064 N PRO A 149 -45.814 -2.786 -22.040 1.00 90.84 N ATOM 1065 CA PRO A 149 -45.352 -2.494 -20.678 1.00 88.92 C ATOM 1066 C PRO A 149 -44.754 -3.713 -19.989 1.00 88.63 C ATOM 1067 O PRO A 149 -45.163 -4.839 -20.263 1.00 90.61 O ATOM 1068 CB PRO A 149 -46.636 -2.076 -19.953 1.00 90.54 C ATOM 1069 CG PRO A 149 -47.592 -1.698 -21.035 1.00 92.57 C ATOM 1070 CD PRO A 149 -47.276 -2.634 -22.149 1.00 91.94 C ATOM 1071 N LYS A 150 -43.790 -3.482 -19.104 1.00 93.26 N ATOM 1072 CA LYS A 150 -43.150 -4.567 -18.359 1.00 96.99 C ATOM 1073 C LYS A 150 -43.752 -4.693 -16.964 1.00 98.16 C ATOM 1074 O LYS A 150 -43.368 -3.971 -16.044 1.00 98.52 O ATOM 1075 CB LYS A 150 -41.637 -4.348 -18.275 1.00 94.89 C ATOM 1076 CG LYS A 150 -40.929 -4.403 -19.615 1.00 94.34 C ATOM 1077 CD LYS A 150 -39.432 -4.278 -19.443 1.00 94.22 C ATOM 1078 CE LYS A 150 -38.711 -4.544 -20.746 1.00 93.65 C ATOM 1079 NZ LYS A 150 -37.250 -4.688 -20.519 1.00 99.17 N ATOM 1080 N GLU A 151 -44.700 -5.614 -16.818 1.00101.18 N ATOM 1081 CA GLU A 151 -45.423 -5.789 -15.558 1.00106.98 C ATOM 1082 C GLU A 151 -44.673 -6.650 -14.542 1.00106.19 C ATOM 1083 O GLU A 151 -44.886 -6.515 -13.335 1.00105.89 O ATOM 1084 CB GLU A 151 -46.831 -6.328 -15.820 1.00111.44 C ATOM 1085 CG GLU A 151 -47.825 -5.230 -16.178 1.00114.90 C ATOM 1086 CD GLU A 151 -48.497 -5.449 -17.520 1.00120.02 C ATOM 1087 OE1 GLU A 151 -48.328 -6.538 -18.113 1.00122.37 O ATOM 1088 OE2 GLU A 151 -49.192 -4.520 -17.989 1.00121.39 O ATOM 1089 N GLY A 152 -43.794 -7.522 -15.033 1.00105.91 N ATOM 1090 CA GLY A 152 -42.926 -8.328 -14.173 1.00107.01 C ATOM 1091 C GLY A 152 -41.954 -7.467 -13.385 1.00110.87 C ATOM 1092 O GLY A 152 -41.555 -7.825 -12.275 1.00111.99 O ATOM 1093 N LYS A 153 -41.581 -6.328 -13.970 1.00112.74 N ATOM 1094 CA LYS A 153 -40.714 -5.339 -13.327 1.00112.07 C ATOM 1095 C LYS A 153 -41.505 -4.313 -12.519 1.00112.08 C ATOM 1096 O LYS A 153 -41.051 -3.864 -11.464 1.00113.75 O ATOM 1097 CB LYS A 153 -39.866 -4.615 -14.371 1.00111.67 C ATOM 1098 CG LYS A 153 -38.588 -5.339 -14.760 1.00112.87 C ATOM 1099 CD LYS A 153 -37.938 -4.706 -15.988 1.00115.64 C ATOM 1100 CE LYS A 153 -37.415 -3.300 -15.711 1.00111.64 C ATOM 1101 NZ LYS A 153 -36.724 -2.737 -16.901 1.00108.06 N ATOM 1102 N ALA A 154 -42.678 -3.939 -13.026 1.00111.53 N ATOM 1103 CA ALA A 154 -43.560 -2.990 -12.349 1.00113.06 C ATOM 1104 C ALA A 154 -44.053 -3.558 -11.024 1.00116.37 C ATOM 1105 O ALA A 154 -44.322 -2.809 -10.084 1.00118.45 O ATOM 1106 CB ALA A 154 -44.735 -2.629 -13.239 1.00113.41 C ATOM 1107 N HIS A 155 -44.165 -4.883 -10.962 1.00117.03 N ATOM 1108 CA HIS A 155 -44.577 -5.567 -9.744 1.00116.61 C ATOM 1109 C HIS A 155 -43.501 -5.499 -8.667 1.00118.32 C ATOM 1110 O HIS A 155 -43.792 -5.132 -7.528 1.00124.59 O ATOM 1111 CB HIS A 155 -44.945 -7.025 -10.024 1.00115.91 C ATOM 1112 CG HIS A 155 -45.428 -7.764 -8.815 1.00117.05 C ATOM 1113 ND1 HIS A 155 -46.538 -7.370 -8.096 1.00115.83 N ATOM 1114 CD2 HIS A 155 -44.952 -8.870 -8.196 1.00115.73 C ATOM 1115 CE1 HIS A 155 -46.724 -8.202 -7.088 1.00118.12 C ATOM 1116 NE2 HIS A 155 -45.775 -9.121 -7.125 1.00118.94 N ATOM 1117 N SER A 156 -42.267 -5.847 -9.033 1.00114.22 N ATOM 1118 CA SER A 156 -41.134 -5.816 -8.105 1.00110.95 C ATOM 1119 C SER A 156 -40.968 -4.457 -7.423 1.00113.12 C ATOM 1120 O SER A 156 -40.553 -4.386 -6.265 1.00116.78 O ATOM 1121 CB SER A 156 -39.840 -6.209 -8.819 1.00108.55 C ATOM 1122 OG SER A 156 -39.845 -7.583 -9.160 1.00109.40 O ATOM 1123 N GLN A 157 -41.309 -3.389 -8.142 1.00110.96 N ATOM 1124 CA GLN A 157 -41.231 -2.024 -7.615 1.00108.29 C ATOM 1125 C GLN A 157 -42.518 -1.601 -6.897 1.00107.43 C ATOM 1126 O GLN A 157 -42.633 -0.464 -6.428 1.00104.29 O ATOM 1127 CB GLN A 157 -40.896 -1.034 -8.740 1.00107.17 C ATOM 1128 CG GLN A 157 -39.556 -1.284 -9.433 1.00102.79 C ATOM 1129 CD GLN A 157 -38.360 -0.896 -8.583 1.00 99.50 C ATOM 1130 OE1 GLN A 157 -38.262 0.236 -8.107 1.00 99.14 O ATOM 1131 NE2 GLN A 157 -37.435 -1.834 -8.399 1.00 96.41 N ATOM 1132 N GLY A 158 -43.478 -2.522 -6.819 1.00108.37 N ATOM 1133 CA GLY A 158 -44.749 -2.288 -6.133 1.00111.66 C ATOM 1134 C GLY A 158 -45.602 -1.203 -6.759 1.00113.18 C ATOM 1135 O GLY A 158 -46.319 -0.490 -6.056 1.00113.49 O ATOM 1136 N CYS A 159 -45.524 -1.077 -8.081 1.00116.91 N ATOM 1137 CA CYS A 159 -46.282 -0.062 -8.806 1.00118.71 C ATOM 1138 C CYS A 159 -47.732 -0.488 -8.949 1.00119.30 C ATOM 1139 O CYS A 159 -48.022 -1.667 -9.170 1.00121.52 O ATOM 1140 CB CYS A 159 -45.675 0.199 -10.189 1.00121.51 C ATOM 1141 SG CYS A 159 -43.916 0.660 -10.196 1.00126.08 S ATOM 1142 N GLY A 160 -48.635 0.480 -8.823 1.00118.56 N ATOM 1143 CA GLY A 160 -50.067 0.229 -8.955 1.00121.30 C ATOM 1144 C GLY A 160 -50.445 -0.147 -10.372 1.00121.41 C ATOM 1145 O GLY A 160 -49.613 -0.089 -11.281 1.00118.37 O ATOM 1146 N GLU A 161 -51.701 -0.540 -10.561 1.00127.28 N ATOM 1147 CA GLU A 161 -52.191 -0.922 -11.886 1.00132.68 C ATOM 1148 C GLU A 161 -52.236 0.277 -12.831 1.00128.95 C ATOM 1149 O GLU A 161 -52.732 1.349 -12.475 1.00130.00 O ATOM 1150 CB GLU A 161 -53.552 -1.628 -11.804 1.00137.70 C ATOM 1151 CG GLU A 161 -54.598 -0.935 -10.935 1.00143.38 C ATOM 1152 CD GLU A 161 -55.828 -1.795 -10.693 1.00148.26 C ATOM 1153 OE1 GLU A 161 -56.225 -2.556 -11.604 1.00148.71 O ATOM 1154 OE2 GLU A 161 -56.403 -1.704 -9.586 1.00151.24 O ATOM 1155 N GLY A 162 -51.696 0.084 -14.031 1.00125.12 N ATOM 1156 CA GLY A 162 -51.548 1.167 -15.000 1.00122.81 C ATOM 1157 C GLY A 162 -50.235 1.913 -14.829 1.00117.42 C ATOM 1158 O GLY A 162 -50.058 3.005 -15.375 1.00114.81 O ATOM 1159 N GLN A 163 -49.316 1.320 -14.068 1.00111.44 N ATOM 1160 CA GLN A 163 -48.012 1.925 -13.812 1.00107.45 C ATOM 1161 C GLN A 163 -46.865 0.971 -14.111 1.00105.34 C ATOM 1162 O GLN A 163 -46.943 -0.226 -13.828 1.00102.43 O ATOM 1163 CB GLN A 163 -47.910 2.421 -12.368 1.00107.24 C ATOM 1164 CG GLN A 163 -48.749 3.655 -12.072 1.00107.62 C ATOM 1165 CD GLN A 163 -48.684 4.077 -10.617 1.00107.28 C ATOM 1166 OE1 GLN A 163 -48.714 3.245 -9.707 1.00107.72 O ATOM 1167 NE2 GLN A 163 -48.604 5.381 -10.389 1.00106.17 N ATOM 1168 N VAL A 164 -45.801 1.525 -14.687 1.00104.35 N ATOM 1169 CA VAL A 164 -44.588 0.780 -15.014 1.00 99.50 C ATOM 1170 C VAL A 164 -43.372 1.431 -14.356 1.00 97.69 C ATOM 1171 O VAL A 164 -43.427 2.598 -13.956 1.00 95.08 O ATOM 1172 CB VAL A 164 -44.360 0.695 -16.545 1.00 99.53 C ATOM 1173 CG1 VAL A 164 -45.423 -0.171 -17.195 1.00100.88 C ATOM 1174 CG2 VAL A 164 -44.330 2.088 -17.178 1.00 98.54 C ATOM 1175 N ALA A 165 -42.285 0.670 -14.242 1.00 95.67 N ATOM 1176 CA ALA A 165 -41.021 1.192 -13.725 1.00 94.07 C ATOM 1177 C ALA A 165 -40.378 2.105 -14.765 1.00 94.37 C ATOM 1178 O ALA A 165 -39.935 1.643 -15.823 1.00 95.63 O ATOM 1179 CB ALA A 165 -40.081 0.053 -13.341 1.00 91.56 C ATOM 1180 N CYS A 166 -40.343 3.399 -14.458 1.00 92.16 N ATOM 1181 CA CYS A 166 -39.877 4.413 -15.397 1.00 91.73 C ATOM 1182 C CYS A 166 -38.369 4.346 -15.662 1.00 91.59 C ATOM 1183 O CYS A 166 -37.572 4.986 -14.973 1.00 92.29 O ATOM 1184 CB CYS A 166 -40.290 5.809 -14.922 1.00 94.96 C ATOM 1185 SG CYS A 166 -39.923 7.146 -16.087 1.00103.72 S ATOM 1186 N LEU A 167 -37.997 3.551 -16.662 1.00 87.95 N ATOM 1187 CA LEU A 167 -36.629 3.505 -17.168 1.00 86.37 C ATOM 1188 C LEU A 167 -36.585 4.040 -18.600 1.00 88.01 C ATOM 1189 O LEU A 167 -37.606 4.052 -19.301 1.00 92.26 O ATOM 1190 CB LEU A 167 -36.071 2.073 -17.123 1.00 86.73 C ATOM 1191 CG LEU A 167 -35.589 1.405 -15.820 1.00 85.63 C ATOM 1192 CD1 LEU A 167 -34.984 2.413 -14.849 1.00 83.90 C ATOM 1193 CD2 LEU A 167 -36.691 0.608 -15.142 1.00 82.72 C ATOM 1194 N PHE A 168 -35.404 4.484 -19.029 1.00 82.55 N ATOM 1195 CA PHE A 168 -35.213 5.003 -20.381 1.00 77.29 C ATOM 1196 C PHE A 168 -35.399 3.872 -21.375 1.00 75.81 C ATOM 1197 O PHE A 168 -36.259 3.940 -22.255 1.00 77.04 O ATOM 1198 CB PHE A 168 -33.817 5.616 -20.531 1.00 75.64 C ATOM 1199 CG PHE A 168 -33.591 6.314 -21.844 1.00 76.60 C ATOM 1200 CD1 PHE A 168 -33.934 7.655 -22.003 1.00 75.19 C ATOM 1201 CD2 PHE A 168 -33.023 5.636 -22.921 1.00 75.39 C ATOM 1202 CE1 PHE A 168 -33.721 8.310 -23.217 1.00 74.10 C ATOM 1203 CE2 PHE A 168 -32.806 6.286 -24.140 1.00 74.93 C ATOM 1204 CZ PHE A 168 -33.155 7.624 -24.286 1.00 73.29 C ATOM 1205 N GLU A 169 -34.598 2.825 -21.197 1.00 73.36 N ATOM 1206 CA GLU A 169 -34.597 1.663 -22.073 1.00 72.76 C ATOM 1207 C GLU A 169 -35.933 0.917 -22.057 1.00 74.42 C ATOM 1208 O GLU A 169 -36.116 -0.060 -22.787 1.00 75.44 O ATOM 1209 CB GLU A 169 -33.435 0.729 -21.711 1.00 71.39 C ATOM 1210 CG GLU A 169 -32.056 1.350 -21.938 1.00 72.29 C ATOM 1211 CD GLU A 169 -30.924 0.329 -22.012 1.00 76.83 C ATOM 1212 OE1 GLU A 169 -31.064 -0.788 -21.462 1.00 77.13 O ATOM 1213 OE2 GLU A 169 -29.878 0.652 -22.620 1.00 79.16 O1- ATOM 1214 N ASP A 170 -36.869 1.398 -21.242 1.00 75.91 N ATOM 1215 CA ASP A 170 -38.192 0.788 -21.124 1.00 75.70 C ATOM 1216 C ASP A 170 -39.258 1.476 -21.968 1.00 75.94 C ATOM 1217 O ASP A 170 -40.253 0.853 -22.333 1.00 77.68 O ATOM 1218 CB ASP A 170 -38.637 0.755 -19.661 1.00 77.12 C ATOM 1219 CG ASP A 170 -38.231 -0.524 -18.950 1.00 79.31 C ATOM 1220 OD1 ASP A 170 -37.311 -1.225 -19.435 1.00 76.74 O ATOM 1221 OD2 ASP A 170 -38.842 -0.824 -17.898 1.00 82.74 O1- ATOM 1222 N VAL A 171 -39.061 2.756 -22.264 1.00 76.38 N ATOM 1223 CA VAL A 171 -40.044 3.517 -23.038 1.00 76.52 C ATOM 1224 C VAL A 171 -39.504 3.983 -24.392 1.00 77.21 C ATOM 1225 O VAL A 171 -40.263 4.110 -25.354 1.00 80.40 O ATOM 1226 CB VAL A 171 -40.618 4.719 -22.239 1.00 78.43 C ATOM 1227 CG1 VAL A 171 -41.431 4.226 -21.052 1.00 78.74 C ATOM 1228 CG2 VAL A 171 -39.506 5.663 -21.773 1.00 77.51 C ATOM 1229 N VAL A 172 -38.198 4.236 -24.456 1.00 74.15 N ATOM 1230 CA VAL A 172 -37.563 4.725 -25.676 1.00 70.74 C ATOM 1231 C VAL A 172 -36.925 3.553 -26.408 1.00 69.43 C ATOM 1232 O VAL A 172 -36.016 2.915 -25.873 1.00 70.61 O ATOM 1233 CB VAL A 172 -36.522 5.835 -25.379 1.00 69.87 C ATOM 1234 CG1 VAL A 172 -35.643 6.106 -26.596 1.00 69.93 C ATOM 1235 CG2 VAL A 172 -37.223 7.112 -24.947 1.00 68.45 C ATOM 1236 N PRO A 173 -37.416 3.257 -27.627 1.00 69.09 N ATOM 1237 CA PRO A 173 -36.965 2.121 -28.440 1.00 67.41 C ATOM 1238 C PRO A 173 -35.508 2.230 -28.876 1.00 66.93 C ATOM 1239 O PRO A 173 -35.025 3.322 -29.187 1.00 65.54 O ATOM 1240 CB PRO A 173 -37.885 2.172 -29.667 1.00 66.86 C ATOM 1241 CG PRO A 173 -39.058 2.962 -29.240 1.00 70.24 C ATOM 1242 CD PRO A 173 -38.531 3.973 -28.270 1.00 71.25 C ATOM 1243 N MET A 174 -34.822 1.092 -28.899 1.00 67.88 N ATOM 1244 CA MET A 174 -33.420 1.044 -29.283 1.00 70.40 C ATOM 1245 C MET A 174 -33.209 1.328 -30.761 1.00 72.60 C ATOM 1246 O MET A 174 -32.168 1.868 -31.142 1.00 77.45 O ATOM 1247 CB MET A 174 -32.797 -0.306 -28.921 1.00 71.76 C ATOM 1248 CG MET A 174 -32.329 -0.428 -27.472 1.00 75.24 C ATOM 1249 SD MET A 174 -31.208 0.876 -26.900 1.00 77.41 S ATOM 1250 CE MET A 174 -30.068 0.988 -28.272 1.00 75.99 C ATOM 1251 N ASN A 175 -34.182 0.955 -31.592 1.00 70.89 N ATOM 1252 CA ASN A 175 -34.090 1.242 -33.021 1.00 70.08 C ATOM 1253 C ASN A 175 -34.213 2.738 -33.302 1.00 68.80 C ATOM 1254 O ASN A 175 -33.496 3.267 -34.152 1.00 69.91 O ATOM 1255 CB ASN A 175 -35.078 0.406 -33.851 1.00 72.25 C ATOM 1256 CG ASN A 175 -36.528 0.624 -33.453 1.00 75.19 C ATOM 1257 OD1 ASN A 175 -36.827 1.204 -32.407 1.00 76.55 O ATOM 1258 ND2 ASN A 175 -37.440 0.150 -34.293 1.00 75.58 N ATOM 1259 N TYR A 176 -35.099 3.417 -32.572 1.00 65.93 N ATOM 1260 CA TYR A 176 -35.161 4.877 -32.614 1.00 65.40 C ATOM 1261 C TYR A 176 -33.809 5.479 -32.242 1.00 67.68 C ATOM 1262 O TYR A 176 -33.326 6.402 -32.902 1.00 68.83 O ATOM 1263 CB TYR A 176 -36.243 5.431 -31.683 1.00 66.32 C ATOM 1264 CG TYR A 176 -36.031 6.897 -31.370 1.00 68.42 C ATOM 1265 CD1 TYR A 176 -36.316 7.882 -32.318 1.00 67.02 C ATOM 1266 CD2 TYR A 176 -35.511 7.297 -30.140 1.00 69.33 C ATOM 1267 CE1 TYR A 176 -36.104 9.223 -32.042 1.00 67.62 C ATOM 1268 CE2 TYR A 176 -35.299 8.638 -29.855 1.00 69.50 C ATOM 1269 CZ TYR A 176 -35.594 9.594 -30.811 1.00 68.99 C ATOM 1270 OH TYR A 176 -35.377 10.921 -30.530 1.00 70.76 O ATOM 1271 N MET A 177 -33.211 4.949 -31.179 1.00 65.98 N ATOM 1272 CA MET A 177 -31.920 5.419 -30.713 1.00 62.51 C ATOM 1273 C MET A 177 -30.832 5.210 -31.750 1.00 61.54 C ATOM 1274 O MET A 177 -30.109 6.143 -32.076 1.00 62.68 O ATOM 1275 CB MET A 177 -31.537 4.747 -29.390 1.00 62.77 C ATOM 1276 CG MET A 177 -32.247 5.319 -28.147 1.00 61.51 C ATOM 1277 SD MET A 177 -32.254 7.127 -28.012 1.00 56.77 S ATOM 1278 CE MET A 177 -30.493 7.499 -27.992 1.00 56.15 C ATOM 1279 N VAL A 178 -30.733 3.995 -32.276 1.00 63.55 N ATOM 1280 CA VAL A 178 -29.641 3.638 -33.178 1.00 66.35 C ATOM 1281 C VAL A 178 -29.855 4.214 -34.574 1.00 68.63 C ATOM 1282 O VAL A 178 -28.967 4.871 -35.114 1.00 69.22 O ATOM 1283 CB VAL A 178 -29.412 2.102 -33.232 1.00 66.48 C ATOM 1284 CG1 VAL A 178 -28.487 1.722 -34.386 1.00 68.02 C ATOM 1285 CG2 VAL A 178 -28.832 1.611 -31.921 1.00 64.52 C ATOM 1286 N TYR A 179 -31.038 3.980 -35.141 1.00 71.88 N ATOM 1287 CA TYR A 179 -31.318 4.351 -36.532 1.00 71.62 C ATOM 1288 C TYR A 179 -31.637 5.821 -36.749 1.00 71.85 C ATOM 1289 O TYR A 179 -31.256 6.383 -37.772 1.00 74.54 O ATOM 1290 CB TYR A 179 -32.446 3.498 -37.115 1.00 70.87 C ATOM 1291 CG TYR A 179 -32.051 2.069 -37.382 1.00 73.03 C ATOM 1292 CD1 TYR A 179 -30.875 1.764 -38.073 1.00 73.72 C ATOM 1293 CD2 TYR A 179 -32.846 1.018 -36.938 1.00 73.80 C ATOM 1294 CE1 TYR A 179 -30.507 0.446 -38.318 1.00 75.07 C ATOM 1295 CE2 TYR A 179 -32.488 -0.300 -37.180 1.00 75.02 C ATOM 1296 CZ TYR A 179 -31.321 -0.579 -37.867 1.00 75.59 C ATOM 1297 OH TYR A 179 -30.970 -1.884 -38.103 1.00 77.28 O ATOM 1298 N PHE A 180 -32.348 6.437 -35.810 1.00 71.01 N ATOM 1299 CA PHE A 180 -32.737 7.833 -35.974 1.00 70.82 C ATOM 1300 C PHE A 180 -31.926 8.791 -35.093 1.00 72.87 C ATOM 1301 O PHE A 180 -31.292 9.714 -35.610 1.00 74.88 O ATOM 1302 CB PHE A 180 -34.250 8.013 -35.788 1.00 68.30 C ATOM 1303 CG PHE A 180 -34.754 9.385 -36.151 1.00 68.84 C ATOM 1304 CD1 PHE A 180 -34.171 10.115 -37.189 1.00 69.95 C ATOM 1305 CD2 PHE A 180 -35.833 9.940 -35.469 1.00 70.47 C ATOM 1306 CE1 PHE A 180 -34.638 11.387 -37.524 1.00 70.69 C ATOM 1307 CE2 PHE A 180 -36.315 11.209 -35.798 1.00 72.08 C ATOM 1308 CZ PHE A 180 -35.714 11.934 -36.828 1.00 72.35 C ATOM 1309 N ASN A 181 -31.924 8.562 -33.782 1.00 71.82 N ATOM 1310 CA ASN A 181 -31.270 9.483 -32.847 1.00 71.23 C ATOM 1311 C ASN A 181 -29.755 9.587 -33.006 1.00 71.62 C ATOM 1312 O ASN A 181 -29.213 10.688 -33.073 1.00 76.12 O ATOM 1313 CB ASN A 181 -31.626 9.152 -31.398 1.00 69.44 C ATOM 1314 CG ASN A 181 -31.394 10.324 -30.471 1.00 68.43 C ATOM 1315 OD1 ASN A 181 -30.254 10.646 -30.131 1.00 67.24 O ATOM 1316 ND2 ASN A 181 -32.478 10.978 -30.062 1.00 66.51 N ATOM 1317 N PHE A 182 -29.083 8.442 -33.062 1.00 69.12 N ATOM 1318 CA PHE A 182 -27.637 8.386 -33.254 1.00 68.51 C ATOM 1319 C PHE A 182 -27.195 9.092 -34.548 1.00 69.32 C ATOM 1320 O PHE A 182 -26.277 9.912 -34.522 1.00 68.54 O ATOM 1321 CB PHE A 182 -27.172 6.920 -33.200 1.00 69.04 C ATOM 1322 CG PHE A 182 -25.688 6.717 -33.386 1.00 68.89 C ATOM 1323 CD1 PHE A 182 -24.763 7.654 -32.941 1.00 69.88 C ATOM 1324 CD2 PHE A 182 -25.220 5.548 -33.974 1.00 69.72 C ATOM 1325 CE1 PHE A 182 -23.399 7.444 -33.114 1.00 73.39 C ATOM 1326 CE2 PHE A 182 -23.859 5.325 -34.141 1.00 72.13 C ATOM 1327 CZ PHE A 182 -22.947 6.274 -33.713 1.00 72.81 C ATOM 1328 N PHE A 183 -27.863 8.794 -35.663 1.00 71.88 N ATOM 1329 CA PHE A 183 -27.508 9.387 -36.959 1.00 73.69 C ATOM 1330 C PHE A 183 -27.867 10.874 -37.064 1.00 71.42 C ATOM 1331 O PHE A 183 -27.074 11.676 -37.564 1.00 68.80 O ATOM 1332 CB PHE A 183 -28.139 8.603 -38.122 1.00 78.63 C ATOM 1333 CG PHE A 183 -27.480 7.272 -38.392 1.00 84.19 C ATOM 1334 CD1 PHE A 183 -26.311 7.196 -39.144 1.00 86.63 C ATOM 1335 CD2 PHE A 183 -28.035 6.092 -37.900 1.00 86.31 C ATOM 1336 CE1 PHE A 183 -25.702 5.966 -39.394 1.00 88.54 C ATOM 1337 CE2 PHE A 183 -27.436 4.856 -38.144 1.00 86.38 C ATOM 1338 CZ PHE A 183 -26.269 4.793 -38.890 1.00 89.46 C ATOM 1339 N ALA A 184 -29.056 11.234 -36.587 1.00 68.48 N ATOM 1340 CA ALA A 184 -29.532 12.608 -36.677 1.00 68.83 C ATOM 1341 C ALA A 184 -28.814 13.546 -35.711 1.00 72.35 C ATOM 1342 O ALA A 184 -28.444 14.660 -36.084 1.00 75.95 O ATOM 1343 CB ALA A 184 -31.032 12.668 -36.453 1.00 69.18 C ATOM 1344 N CYS A 185 -28.614 13.096 -34.475 1.00 73.15 N ATOM 1345 CA CYS A 185 -28.082 13.972 -33.435 1.00 72.79 C ATOM 1346 C CYS A 185 -26.567 13.940 -33.303 1.00 71.61 C ATOM 1347 O CYS A 185 -25.958 14.954 -32.968 1.00 75.16 O ATOM 1348 CB CYS A 185 -28.740 13.690 -32.085 1.00 73.98 C ATOM 1349 SG CYS A 185 -30.496 14.101 -32.050 1.00 83.99 S ATOM 1350 N VAL A 186 -25.951 12.795 -33.566 1.00 66.09 N ATOM 1351 CA VAL A 186 -24.520 12.684 -33.325 1.00 66.26 C ATOM 1352 C VAL A 186 -23.673 12.555 -34.590 1.00 66.08 C ATOM 1353 O VAL A 186 -22.886 13.452 -34.892 1.00 68.62 O ATOM 1354 CB VAL A 186 -24.190 11.597 -32.269 1.00 67.45 C ATOM 1355 CG1 VAL A 186 -22.684 11.342 -32.193 1.00 67.10 C ATOM 1356 CG2 VAL A 186 -24.730 12.025 -30.903 1.00 65.84 C ATOM 1357 N LEU A 187 -23.840 11.465 -35.330 1.00 63.97 N ATOM 1358 CA LEU A 187 -22.969 11.172 -36.465 1.00 63.92 C ATOM 1359 C LEU A 187 -22.950 12.255 -37.559 1.00 63.68 C ATOM 1360 O LEU A 187 -21.873 12.633 -38.035 1.00 63.71 O ATOM 1361 CB LEU A 187 -23.303 9.803 -37.056 1.00 68.00 C ATOM 1362 CG LEU A 187 -22.176 9.127 -37.830 1.00 71.63 C ATOM 1363 CD1 LEU A 187 -21.043 8.711 -36.895 1.00 73.81 C ATOM 1364 CD2 LEU A 187 -22.716 7.930 -38.591 1.00 75.54 C ATOM 1365 N VAL A 188 -24.122 12.749 -37.962 1.00 61.28 N ATOM 1366 CA VAL A 188 -24.177 13.824 -38.960 1.00 62.25 C ATOM 1367 C VAL A 188 -23.506 15.114 -38.438 1.00 63.09 C ATOM 1368 O VAL A 188 -22.496 15.546 -39.005 1.00 62.61 O ATOM 1369 CB VAL A 188 -25.613 14.056 -39.537 1.00 62.46 C ATOM 1370 CG1 VAL A 188 -25.748 15.438 -40.197 1.00 60.54 C ATOM 1371 CG2 VAL A 188 -25.961 12.965 -40.532 1.00 62.47 C ATOM 1372 N PRO A 189 -24.033 15.715 -37.349 1.00 62.30 N ATOM 1373 CA PRO A 189 -23.355 16.916 -36.863 1.00 63.38 C ATOM 1374 C PRO A 189 -21.858 16.704 -36.622 1.00 64.87 C ATOM 1375 O PRO A 189 -21.071 17.616 -36.877 1.00 66.96 O ATOM 1376 CB PRO A 189 -24.086 17.229 -35.555 1.00 64.48 C ATOM 1377 CG PRO A 189 -25.454 16.678 -35.765 1.00 64.15 C ATOM 1378 CD PRO A 189 -25.245 15.419 -36.558 1.00 62.56 C ATOM 1379 N LEU A 190 -21.468 15.514 -36.161 1.00 66.01 N ATOM 1380 CA LEU A 190 -20.045 15.182 -35.996 1.00 67.55 C ATOM 1381 C LEU A 190 -19.289 15.218 -37.322 1.00 69.50 C ATOM 1382 O LEU A 190 -18.202 15.787 -37.388 1.00 71.58 O ATOM 1383 CB LEU A 190 -19.854 13.821 -35.313 1.00 66.51 C ATOM 1384 CG LEU A 190 -18.434 13.253 -35.169 1.00 66.52 C ATOM 1385 CD1 LEU A 190 -17.590 14.049 -34.182 1.00 67.29 C ATOM 1386 CD2 LEU A 190 -18.495 11.800 -34.739 1.00 68.15 C ATOM 1387 N LEU A 191 -19.866 14.623 -38.367 1.00 70.61 N ATOM 1388 CA LEU A 191 -19.233 14.624 -39.689 1.00 73.47 C ATOM 1389 C LEU A 191 -19.114 16.020 -40.286 1.00 73.80 C ATOM 1390 O LEU A 191 -18.081 16.358 -40.870 1.00 76.78 O ATOM 1391 CB LEU A 191 -19.963 13.708 -40.671 1.00 76.17 C ATOM 1392 CG LEU A 191 -19.673 12.206 -40.674 1.00 80.35 C ATOM 1393 CD1 LEU A 191 -20.097 11.638 -42.018 1.00 84.35 C ATOM 1394 CD2 LEU A 191 -18.206 11.883 -40.409 1.00 80.86 C ATOM 1395 N LEU A 192 -20.168 16.822 -40.138 1.00 71.50 N ATOM 1396 CA LEU A 192 -20.171 18.195 -40.644 1.00 72.18 C ATOM 1397 C LEU A 192 -19.115 19.059 -39.955 1.00 72.92 C ATOM 1398 O LEU A 192 -18.357 19.762 -40.624 1.00 73.13 O ATOM 1399 CB LEU A 192 -21.561 18.831 -40.518 1.00 71.49 C ATOM 1400 CG LEU A 192 -22.637 18.360 -41.500 1.00 70.44 C ATOM 1401 CD1 LEU A 192 -24.015 18.863 -41.091 1.00 67.48 C ATOM 1402 CD2 LEU A 192 -22.301 18.789 -42.924 1.00 69.73 C ATOM 1403 N MET A 193 -19.061 18.988 -38.626 1.00 72.21 N ATOM 1404 CA MET A 193 -18.068 19.730 -37.853 1.00 73.80 C ATOM 1405 C MET A 193 -16.661 19.286 -38.231 1.00 73.86 C ATOM 1406 O MET A 193 -15.775 20.117 -38.447 1.00 74.47 O ATOM 1407 CB MET A 193 -18.290 19.547 -36.348 1.00 74.70 C ATOM 1408 CG MET A 193 -19.508 20.266 -35.789 1.00 73.47 C ATOM 1409 SD MET A 193 -19.609 20.248 -33.987 1.00 74.91 S ATOM 1410 CE MET A 193 -19.789 18.499 -33.622 1.00 72.13 C ATOM 1411 N LEU A 194 -16.472 17.970 -38.316 1.00 74.66 N ATOM 1412 CA LEU A 194 -15.204 17.387 -38.743 1.00 76.25 C ATOM 1413 C LEU A 194 -14.816 17.916 -40.126 1.00 77.21 C ATOM 1414 O LEU A 194 -13.677 18.342 -40.334 1.00 76.64 O ATOM 1415 CB LEU A 194 -15.288 15.854 -38.736 1.00 74.09 C ATOM 1416 CG LEU A 194 -13.988 15.040 -38.738 1.00 74.94 C ATOM 1417 CD1 LEU A 194 -13.093 15.391 -37.561 1.00 74.33 C ATOM 1418 CD2 LEU A 194 -14.299 13.553 -38.731 1.00 75.87 C ATOM 1419 N GLY A 195 -15.780 17.908 -41.051 1.00 76.86 N ATOM 1420 CA GLY A 195 -15.604 18.471 -42.390 1.00 74.80 C ATOM 1421 C GLY A 195 -15.213 19.939 -42.374 1.00 75.30 C ATOM 1422 O GLY A 195 -14.346 20.364 -43.142 1.00 76.37 O ATOM 1423 N VAL A 196 -15.853 20.709 -41.494 1.00 74.68 N ATOM 1424 CA VAL A 196 -15.541 22.129 -41.305 1.00 72.34 C ATOM 1425 C VAL A 196 -14.107 22.313 -40.808 1.00 71.79 C ATOM 1426 O VAL A 196 -13.352 23.110 -41.368 1.00 71.99 O ATOM 1427 CB VAL A 196 -16.539 22.811 -40.337 1.00 71.17 C ATOM 1428 CG1 VAL A 196 -16.015 24.160 -39.877 1.00 71.25 C ATOM 1429 CG2 VAL A 196 -17.895 22.974 -41.002 1.00 69.55 C ATOM 1430 N TYR A 197 -13.738 21.564 -39.772 1.00 71.26 N ATOM 1431 CA TYR A 197 -12.378 21.595 -39.243 1.00 72.02 C ATOM 1432 C TYR A 197 -11.333 21.304 -40.327 1.00 73.30 C ATOM 1433 O TYR A 197 -10.363 22.046 -40.473 1.00 74.46 O ATOM 1434 CB TYR A 197 -12.232 20.629 -38.061 1.00 70.65 C ATOM 1435 CG TYR A 197 -10.798 20.342 -37.698 1.00 70.81 C ATOM 1436 CD1 TYR A 197 -10.010 21.309 -37.078 1.00 70.57 C ATOM 1437 CD2 TYR A 197 -10.223 19.107 -37.986 1.00 73.37 C ATOM 1438 CE1 TYR A 197 -8.686 21.053 -36.753 1.00 72.41 C ATOM 1439 CE2 TYR A 197 -8.897 18.838 -37.660 1.00 75.09 C ATOM 1440 CZ TYR A 197 -8.137 19.817 -37.043 1.00 73.78 C ATOM 1441 OH TYR A 197 -6.825 19.565 -36.724 1.00 74.51 O ATOM 1442 N LEU A 198 -11.547 20.240 -41.095 1.00 76.12 N ATOM 1443 CA LEU A 198 -10.626 19.864 -42.169 1.00 79.86 C ATOM 1444 C LEU A 198 -10.518 20.934 -43.259 1.00 82.52 C ATOM 1445 O LEU A 198 -9.500 21.020 -43.943 1.00 84.28 O ATOM 1446 CB LEU A 198 -11.008 18.504 -42.772 1.00 79.52 C ATOM 1447 CG LEU A 198 -10.919 17.290 -41.832 1.00 81.43 C ATOM 1448 CD1 LEU A 198 -11.852 16.179 -42.290 1.00 83.20 C ATOM 1449 CD2 LEU A 198 -9.486 16.766 -41.660 1.00 79.36 C ATOM 1450 N ARG A 199 -11.559 21.749 -43.408 1.00 85.91 N ATOM 1451 CA ARG A 199 -11.541 22.845 -44.377 1.00 90.31 C ATOM 1452 C ARG A 199 -10.842 24.090 -43.835 1.00 90.66 C ATOM 1453 O ARG A 199 -10.395 24.941 -44.608 1.00 89.86 O ATOM 1454 CB ARG A 199 -12.957 23.180 -44.863 1.00 96.69 C ATOM 1455 CG ARG A 199 -13.521 22.191 -45.887 1.00105.38 C ATOM 1456 CD ARG A 199 -12.784 22.270 -47.225 1.00113.73 C ATOM 1457 NE ARG A 199 -12.930 21.043 -48.009 1.00118.54 N ATOM 1458 CZ ARG A 199 -12.186 20.727 -49.068 1.00120.96 C ATOM 1459 NH1 ARG A 199 -11.226 21.545 -49.486 1.00117.51 N ATOM 1460 NH2 ARG A 199 -12.402 19.585 -49.710 1.00122.26 N ATOM 1461 N ILE A 200 -10.758 24.191 -42.508 1.00 87.16 N ATOM 1462 CA ILE A 200 -10.024 25.274 -41.855 1.00 82.46 C ATOM 1463 C ILE A 200 -8.559 24.882 -41.684 1.00 84.02 C ATOM 1464 O ILE A 200 -7.665 25.731 -41.769 1.00 87.52 O ATOM 1465 CB ILE A 200 -10.662 25.672 -40.504 1.00 80.59 C ATOM 1466 CG1 ILE A 200 -12.002 26.371 -40.760 1.00 80.46 C ATOM 1467 CG2 ILE A 200 -9.726 26.579 -39.692 1.00 80.81 C ATOM 1468 CD1 ILE A 200 -12.666 26.960 -39.534 1.00 78.29 C ATOM 1469 N PHE A 201 -8.324 23.592 -41.457 1.00 83.05 N ATOM 1470 CA PHE A 201 -6.972 23.053 -41.376 1.00 82.70 C ATOM 1471 C PHE A 201 -6.252 23.201 -42.718 1.00 82.47 C ATOM 1472 O PHE A 201 -5.152 23.751 -42.769 1.00 81.90 O ATOM 1473 CB PHE A 201 -7.002 21.587 -40.930 1.00 85.95 C ATOM 1474 CG PHE A 201 -5.645 21.013 -40.636 1.00 88.74 C ATOM 1475 CD1 PHE A 201 -5.010 21.278 -39.422 1.00 89.80 C ATOM 1476 CD2 PHE A 201 -5.003 20.202 -41.568 1.00 87.42 C ATOM 1477 CE1 PHE A 201 -3.755 20.751 -39.145 1.00 88.39 C ATOM 1478 CE2 PHE A 201 -3.748 19.668 -41.301 1.00 86.81 C ATOM 1479 CZ PHE A 201 -3.124 19.943 -40.086 1.00 89.65 C ATOM 1480 N LEU A 202 -6.889 22.730 -43.794 1.00 80.93 N ATOM 1481 CA LEU A 202 -6.358 22.848 -45.159 1.00 79.30 C ATOM 1482 C LEU A 202 -6.086 24.290 -45.597 1.00 78.81 C ATOM 1483 O LEU A 202 -5.181 24.540 -46.395 1.00 78.17 O ATOM 1484 CB LEU A 202 -7.302 22.179 -46.165 1.00 80.35 C ATOM 1485 CG LEU A 202 -7.018 20.769 -46.699 1.00 81.84 C ATOM 1486 CD1 LEU A 202 -5.784 20.760 -47.598 1.00 86.27 C ATOM 1487 CD2 LEU A 202 -6.884 19.734 -45.583 1.00 84.02 C ATOM 1488 N ALA A 203 -6.880 25.225 -45.079 1.00 77.92 N ATOM 1489 CA ALA A 203 -6.689 26.649 -45.344 1.00 78.40 C ATOM 1490 C ALA A 203 -5.389 27.161 -44.725 1.00 78.98 C ATOM 1491 O ALA A 203 -4.713 28.008 -45.307 1.00 76.41 O ATOM 1492 CB ALA A 203 -7.875 27.447 -44.829 1.00 77.65 C ATOM 1493 N ALA A 204 -5.049 26.641 -43.547 1.00 80.35 N ATOM 1494 CA ALA A 204 -3.800 26.992 -42.873 1.00 82.90 C ATOM 1495 C ALA A 204 -2.585 26.363 -43.565 1.00 85.21 C ATOM 1496 O ALA A 204 -1.524 26.987 -43.656 1.00 82.77 O ATOM 1497 CB ALA A 204 -3.853 26.592 -41.401 1.00 79.04 C ATOM 1498 N ARG A 205 -2.752 25.136 -44.058 1.00 88.29 N ATOM 1499 CA ARG A 205 -1.664 24.403 -44.702 1.00 91.99 C ATOM 1500 C ARG A 205 -1.232 25.054 -46.019 1.00 95.85 C ATOM 1501 O ARG A 205 -0.045 25.064 -46.349 1.00 98.17 O ATOM 1502 CB ARG A 205 -2.042 22.934 -44.915 1.00 91.43 C ATOM 1503 CG ARG A 205 -0.841 22.010 -45.061 1.00 95.67 C ATOM 1504 CD ARG A 205 -1.237 20.545 -45.049 1.00100.52 C ATOM 1505 NE ARG A 205 -1.796 20.111 -46.328 1.00106.78 N ATOM 1506 CZ ARG A 205 -2.134 18.856 -46.617 1.00111.16 C ATOM 1507 NH1 ARG A 205 -1.973 17.891 -45.720 1.00112.90 N ATOM 1508 NH2 ARG A 205 -2.636 18.564 -47.810 1.00112.77 N ATOM 1509 N ARG A 206 -2.195 25.602 -46.757 1.00 99.72 N ATOM 1510 CA ARG A 206 -1.898 26.312 -48.003 1.00102.97 C ATOM 1511 C ARG A 206 -1.250 27.667 -47.731 1.00 99.12 C ATOM 1512 O ARG A 206 -0.426 28.130 -48.517 1.00 99.88 O ATOM 1513 CB ARG A 206 -3.151 26.462 -48.872 1.00109.04 C ATOM 1514 CG ARG A 206 -3.708 25.132 -49.373 1.00116.81 C ATOM 1515 CD ARG A 206 -4.822 25.321 -50.396 1.00122.20 C ATOM 1516 NE ARG A 206 -5.619 24.104 -50.566 1.00126.73 N ATOM 1517 CZ ARG A 206 -5.341 23.121 -51.422 1.00129.37 C ATOM 1518 NH1 ARG A 206 -4.276 23.185 -52.214 1.00125.74 N ATOM 1519 NH2 ARG A 206 -6.137 22.061 -51.485 1.00130.85 N ATOM 1520 N GLN A 207 -1.623 28.293 -46.616 1.00 98.70 N ATOM 1521 CA GLN A 207 -0.965 29.516 -46.152 1.00 99.42 C ATOM 1522 C GLN A 207 0.450 29.202 -45.671 1.00 98.46 C ATOM 1523 O GLN A 207 1.364 30.014 -45.825 1.00 97.60 O ATOM 1524 CB GLN A 207 -1.760 30.174 -45.019 1.00101.24 C ATOM 1525 CG GLN A 207 -3.106 30.751 -45.426 1.00105.07 C ATOM 1526 CD GLN A 207 -2.990 32.111 -46.076 1.00109.01 C ATOM 1527 OE1 GLN A 207 -2.919 32.222 -47.301 1.00112.03 O ATOM 1528 NE2 GLN A 207 -2.965 33.157 -45.257 1.00109.66 N ATOM 1529 N LEU A 208 0.619 28.016 -45.089 1.00 95.85 N ATOM 1530 CA LEU A 208 1.913 27.586 -44.581 1.00 94.54 C ATOM 1531 C LEU A 208 2.844 27.137 -45.705 1.00 94.68 C ATOM 1532 O LEU A 208 4.062 27.270 -45.593 1.00 97.30 O ATOM 1533 CB LEU A 208 1.741 26.476 -43.544 1.00 92.63 C ATOM 1534 CG LEU A 208 2.816 26.371 -42.458 1.00 93.79 C ATOM 1535 CD1 LEU A 208 2.873 27.630 -41.592 1.00 89.97 C ATOM 1536 CD2 LEU A 208 2.565 25.144 -41.599 1.00 95.72 C ATOM 1537 N LYS A 209 2.268 26.612 -46.785 1.00 95.18 N ATOM 1538 CA LYS A 209 3.041 26.229 -47.966 1.00 95.74 C ATOM 1539 C LYS A 209 3.529 27.465 -48.727 1.00 99.32 C ATOM 1540 O LYS A 209 4.556 27.416 -49.409 1.00102.20 O ATOM 1541 CB LYS A 209 2.221 25.319 -48.887 1.00 94.34 C ATOM 1542 CG LYS A 209 3.049 24.585 -49.934 1.00 95.60 C ATOM 1543 CD LYS A 209 2.193 23.679 -50.799 1.00 99.63 C ATOM 1544 CE LYS A 209 3.050 22.920 -51.804 1.00101.94 C ATOM 1545 NZ LYS A 209 2.238 22.036 -52.690 1.00104.44 N ATOM 1546 N GLN A 210 2.791 28.567 -48.601 1.00100.35 N ATOM 1547 CA GLN A 210 3.150 29.824 -49.257 1.00101.30 C ATOM 1548 C GLN A 210 4.323 30.527 -48.584 1.00 99.87 C ATOM 1549 O GLN A 210 5.070 31.254 -49.240 1.00102.71 O ATOM 1550 CB GLN A 210 1.948 30.764 -49.330 1.00104.98 C ATOM 1551 CG GLN A 210 1.049 30.517 -50.533 1.00111.23 C ATOM 1552 CD GLN A 210 -0.203 31.380 -50.530 1.00113.18 C ATOM 1553 OE1 GLN A 210 -0.296 32.368 -49.798 1.00114.60 O ATOM 1554 NE2 GLN A 210 -1.175 31.007 -51.354 1.00111.91 N ATOM 1555 N MET A 211 4.480 30.310 -47.281 1.00 96.99 N ATOM 1556 CA MET A 211 5.582 30.902 -46.523 1.00 98.01 C ATOM 1557 C MET A 211 6.933 30.284 -46.891 1.00100.72 C ATOM 1558 O MET A 211 7.989 30.815 -46.535 1.00100.92 O ATOM 1559 CB MET A 211 5.328 30.777 -45.021 1.00 98.24 C ATOM 1560 CG MET A 211 4.295 31.753 -44.492 1.00 99.55 C ATOM 1561 SD MET A 211 4.159 31.689 -42.699 1.00102.93 S ATOM 1562 CE MET A 211 3.239 33.188 -42.362 1.00100.47 C ATOM 1563 N GLU A 212 6.887 29.163 -47.607 1.00 99.53 N ATOM 1564 CA GLU A 212 8.088 28.492 -48.084 1.00 98.74 C ATOM 1565 C GLU A 212 8.720 29.226 -49.268 1.00104.98 C ATOM 1566 O GLU A 212 9.943 29.276 -49.379 1.00113.41 O ATOM 1567 CB GLU A 212 7.786 27.036 -48.437 1.00 93.87 C ATOM 1568 CG GLU A 212 7.347 26.210 -47.237 1.00 96.14 C ATOM 1569 CD GLU A 212 7.124 24.744 -47.556 1.00 99.43 C ATOM 1570 OE1 GLU A 212 6.945 24.403 -48.746 1.00 99.65 O ATOM 1571 OE2 GLU A 212 7.121 23.930 -46.607 1.00102.70 O ATOM 1572 N SER A 213 7.889 29.798 -50.141 1.00105.13 N ATOM 1573 CA SER A 213 8.374 30.561 -51.297 1.00101.75 C ATOM 1574 C SER A 213 8.864 31.955 -50.918 1.00100.46 C ATOM 1575 O SER A 213 8.166 32.708 -50.243 1.00 98.15 O ATOM 1576 CB SER A 213 7.295 30.661 -52.373 1.00101.73 C ATOM 1577 OG SER A 213 7.149 29.424 -53.044 1.00110.92 O ATOM 1578 N THR A 224 -4.154 36.433 -41.418 1.00112.81 N ATOM 1579 CA THR A 224 -5.173 35.404 -41.612 1.00112.04 C ATOM 1580 C THR A 224 -4.697 34.049 -41.085 1.00113.23 C ATOM 1581 O THR A 224 -5.483 33.296 -40.506 1.00116.71 O ATOM 1582 CB THR A 224 -5.583 35.272 -43.102 1.00110.53 C ATOM 1583 OG1 THR A 224 -5.778 36.574 -43.666 1.00110.44 O ATOM 1584 CG2 THR A 224 -6.876 34.476 -43.242 1.00110.72 C ATOM 1585 N LEU A 225 -3.412 33.753 -41.283 1.00111.03 N ATOM 1586 CA LEU A 225 -2.819 32.485 -40.850 1.00107.35 C ATOM 1587 C LEU A 225 -2.912 32.275 -39.335 1.00104.17 C ATOM 1588 O LEU A 225 -3.152 31.160 -38.879 1.00101.49 O ATOM 1589 CB LEU A 225 -1.365 32.374 -41.339 1.00107.40 C ATOM 1590 CG LEU A 225 -0.557 31.064 -41.263 1.00108.05 C ATOM 1591 CD1 LEU A 225 0.199 30.950 -39.951 1.00105.50 C ATOM 1592 CD2 LEU A 225 -1.403 29.809 -41.494 1.00106.88 C ATOM 1593 N GLN A 226 -2.734 33.349 -38.570 1.00105.27 N ATOM 1594 CA GLN A 226 -2.838 33.298 -37.109 1.00105.56 C ATOM 1595 C GLN A 226 -4.277 33.052 -36.649 1.00105.50 C ATOM 1596 O GLN A 226 -4.507 32.398 -35.628 1.00104.64 O ATOM 1597 CB GLN A 226 -2.286 34.586 -36.490 1.00107.13 C ATOM 1598 CG GLN A 226 -2.016 34.507 -34.989 1.00109.94 C ATOM 1599 CD GLN A 226 -0.947 35.489 -34.527 1.00113.36 C ATOM 1600 OE1 GLN A 226 -0.588 36.425 -35.245 1.00114.67 O ATOM 1601 NE2 GLN A 226 -0.431 35.275 -33.320 1.00112.26 N ATOM 1602 N LYS A 227 -5.236 33.580 -37.407 1.00104.99 N ATOM 1603 CA LYS A 227 -6.655 33.352 -37.145 1.00104.37 C ATOM 1604 C LYS A 227 -7.045 31.899 -37.423 1.00103.14 C ATOM 1605 O LYS A 227 -7.748 31.272 -36.625 1.00102.68 O ATOM 1606 CB LYS A 227 -7.518 34.300 -37.986 1.00106.61 C ATOM 1607 CG LYS A 227 -7.718 35.684 -37.379 1.00107.26 C ATOM 1608 CD LYS A 227 -8.600 36.558 -38.270 1.00103.85 C ATOM 1609 CE LYS A 227 -9.208 37.724 -37.495 1.00102.24 C ATOM 1610 NZ LYS A 227 -8.197 38.717 -37.038 1.00 97.69 N ATOM 1611 N GLU A 228 -6.568 31.373 -38.551 1.00 98.64 N ATOM 1612 CA GLU A 228 -6.933 30.036 -39.017 1.00 94.44 C ATOM 1613 C GLU A 228 -6.330 28.905 -38.185 1.00 89.83 C ATOM 1614 O GLU A 228 -6.933 27.838 -38.061 1.00 87.22 O ATOM 1615 CB GLU A 228 -6.578 29.868 -40.495 1.00 95.75 C ATOM 1616 CG GLU A 228 -7.440 30.717 -41.418 1.00100.74 C ATOM 1617 CD GLU A 228 -7.118 30.517 -42.884 1.00106.43 C ATOM 1618 OE1 GLU A 228 -5.936 30.294 -43.219 1.00112.34 O1- ATOM 1619 OE2 GLU A 228 -8.054 30.586 -43.706 1.00111.86 O ATOM 1620 N VAL A 229 -5.146 29.141 -37.623 1.00 84.87 N ATOM 1621 CA VAL A 229 -4.500 28.170 -36.734 1.00 83.37 C ATOM 1622 C VAL A 229 -5.247 28.096 -35.399 1.00 84.59 C ATOM 1623 O VAL A 229 -5.494 27.006 -34.872 1.00 83.97 O ATOM 1624 CB VAL A 229 -2.993 28.491 -36.517 1.00 79.35 C ATOM 1625 CG1 VAL A 229 -2.385 27.600 -35.442 1.00 76.85 C ATOM 1626 CG2 VAL A 229 -2.227 28.329 -37.819 1.00 78.47 C ATOM 1627 N HIS A 230 -5.614 29.261 -34.868 1.00 85.26 N ATOM 1628 CA HIS A 230 -6.404 29.339 -33.645 1.00 85.26 C ATOM 1629 C HIS A 230 -7.801 28.734 -33.844 1.00 85.26 C ATOM 1630 O HIS A 230 -8.241 27.900 -33.043 1.00 84.53 O ATOM 1631 CB HIS A 230 -6.485 30.787 -33.150 1.00 85.81 C ATOM 1632 CG HIS A 230 -7.523 31.006 -32.096 1.00 87.64 C ATOM 1633 ND1 HIS A 230 -8.721 31.640 -32.353 1.00 90.47 N ATOM 1634 CD2 HIS A 230 -7.553 30.659 -30.788 1.00 85.23 C ATOM 1635 CE1 HIS A 230 -9.440 31.680 -31.246 1.00 91.58 C ATOM 1636 NE2 HIS A 230 -8.755 31.089 -30.282 1.00 88.94 N ATOM 1637 N ALA A 231 -8.479 29.142 -34.919 1.00 81.13 N ATOM 1638 CA ALA A 231 -9.789 28.588 -35.268 1.00 77.86 C ATOM 1639 C ALA A 231 -9.744 27.066 -35.421 1.00 76.43 C ATOM 1640 O ALA A 231 -10.655 26.367 -34.970 1.00 76.54 O ATOM 1641 CB ALA A 231 -10.323 29.235 -36.532 1.00 75.73 C ATOM 1642 N ALA A 232 -8.680 26.562 -36.046 1.00 73.67 N ATOM 1643 CA ALA A 232 -8.500 25.127 -36.235 1.00 71.83 C ATOM 1644 C ALA A 232 -8.440 24.400 -34.902 1.00 72.39 C ATOM 1645 O ALA A 232 -9.129 23.399 -34.718 1.00 73.83 O ATOM 1646 CB ALA A 232 -7.259 24.838 -37.059 1.00 73.29 C ATOM 1647 N LYS A 233 -7.639 24.910 -33.967 1.00 74.56 N ATOM 1648 CA LYS A 233 -7.518 24.268 -32.657 1.00 74.92 C ATOM 1649 C LYS A 233 -8.805 24.390 -31.853 1.00 73.39 C ATOM 1650 O LYS A 233 -9.162 23.475 -31.109 1.00 73.49 O ATOM 1651 CB LYS A 233 -6.339 24.803 -31.845 1.00 75.01 C ATOM 1652 CG LYS A 233 -5.745 23.729 -30.948 1.00 79.37 C ATOM 1653 CD LYS A 233 -5.342 24.253 -29.583 1.00 84.82 C ATOM 1654 CE LYS A 233 -4.848 23.110 -28.694 1.00 86.66 C ATOM 1655 NZ LYS A 233 -4.106 23.604 -27.495 1.00 90.73 N ATOM 1656 N SER A 234 -9.493 25.519 -32.007 1.00 72.02 N ATOM 1657 CA SER A 234 -10.803 25.711 -31.394 1.00 74.62 C ATOM 1658 C SER A 234 -11.803 24.676 -31.914 1.00 73.76 C ATOM 1659 O SER A 234 -12.547 24.067 -31.140 1.00 71.62 O ATOM 1660 CB SER A 234 -11.309 27.132 -31.641 1.00 79.33 C ATOM 1661 OG SER A 234 -10.739 28.033 -30.706 1.00 86.25 O ATOM 1662 N LEU A 235 -11.793 24.465 -33.225 1.00 72.57 N ATOM 1663 CA LEU A 235 -12.639 23.455 -33.837 1.00 72.70 C ATOM 1664 C LEU A 235 -12.210 22.038 -33.476 1.00 71.99 C ATOM 1665 O LEU A 235 -13.057 21.165 -33.275 1.00 73.35 O ATOM 1666 CB LEU A 235 -12.680 23.640 -35.348 1.00 73.69 C ATOM 1667 CG LEU A 235 -13.908 24.351 -35.923 1.00 77.21 C ATOM 1668 CD1 LEU A 235 -14.269 25.660 -35.214 1.00 75.66 C ATOM 1669 CD2 LEU A 235 -13.661 24.599 -37.388 1.00 81.46 C ATOM 1670 N ALA A 236 -10.902 21.814 -33.386 1.00 68.88 N ATOM 1671 CA ALA A 236 -10.385 20.511 -32.982 1.00 69.78 C ATOM 1672 C ALA A 236 -10.812 20.167 -31.552 1.00 71.32 C ATOM 1673 O ALA A 236 -11.075 19.004 -31.241 1.00 71.38 O ATOM 1674 CB ALA A 236 -8.871 20.456 -33.131 1.00 68.31 C ATOM 1675 N ILE A 237 -10.898 21.179 -30.690 1.00 72.59 N ATOM 1676 CA ILE A 237 -11.367 20.965 -29.322 1.00 77.71 C ATOM 1677 C ILE A 237 -12.861 20.606 -29.296 1.00 78.19 C ATOM 1678 O ILE A 237 -13.250 19.608 -28.676 1.00 78.50 O ATOM 1679 CB ILE A 237 -11.037 22.168 -28.391 1.00 81.33 C ATOM 1680 CG1 ILE A 237 -9.538 22.178 -28.062 1.00 81.65 C ATOM 1681 CG2 ILE A 237 -11.849 22.099 -27.092 1.00 80.22 C ATOM 1682 CD1 ILE A 237 -9.036 23.461 -27.417 1.00 80.27 C ATOM 1683 N ILE A 238 -13.680 21.406 -29.983 1.00 75.19 N ATOM 1684 CA ILE A 238 -15.125 21.168 -30.073 1.00 72.55 C ATOM 1685 C ILE A 238 -15.436 19.733 -30.519 1.00 72.20 C ATOM 1686 O ILE A 238 -16.202 19.022 -29.864 1.00 69.22 O ATOM 1687 CB ILE A 238 -15.817 22.190 -31.026 1.00 74.28 C ATOM 1688 CG1 ILE A 238 -15.768 23.609 -30.436 1.00 74.55 C ATOM 1689 CG2 ILE A 238 -17.269 21.781 -31.306 1.00 76.02 C ATOM 1690 CD1 ILE A 238 -16.023 24.736 -31.443 1.00 69.47 C ATOM 1691 N VAL A 239 -14.815 19.315 -31.622 1.00 73.35 N ATOM 1692 CA VAL A 239 -15.086 18.017 -32.245 1.00 71.22 C ATOM 1693 C VAL A 239 -14.533 16.845 -31.427 1.00 70.36 C ATOM 1694 O VAL A 239 -15.228 15.844 -31.230 1.00 70.14 O ATOM 1695 CB VAL A 239 -14.571 17.974 -33.707 1.00 71.23 C ATOM 1696 CG1 VAL A 239 -14.807 16.609 -34.330 1.00 74.11 C ATOM 1697 CG2 VAL A 239 -15.256 19.040 -34.540 1.00 69.31 C ATOM 1698 N GLY A 240 -13.295 16.977 -30.950 1.00 68.71 N ATOM 1699 CA GLY A 240 -12.670 15.957 -30.105 1.00 66.74 C ATOM 1700 C GLY A 240 -13.477 15.680 -28.847 1.00 68.93 C ATOM 1701 O GLY A 240 -13.732 14.524 -28.502 1.00 69.16 O ATOM 1702 N LEU A 241 -13.890 16.746 -28.168 1.00 68.60 N ATOM 1703 CA LEU A 241 -14.695 16.618 -26.960 1.00 69.83 C ATOM 1704 C LEU A 241 -16.099 16.100 -27.251 1.00 71.33 C ATOM 1705 O LEU A 241 -16.641 15.302 -26.484 1.00 69.58 O ATOM 1706 CB LEU A 241 -14.762 17.947 -26.206 1.00 70.39 C ATOM 1707 CG LEU A 241 -13.494 18.353 -25.449 1.00 72.70 C ATOM 1708 CD1 LEU A 241 -13.690 19.723 -24.840 1.00 75.59 C ATOM 1709 CD2 LEU A 241 -13.107 17.338 -24.370 1.00 69.12 C ATOM 1710 N PHE A 242 -16.676 16.553 -28.363 1.00 72.23 N ATOM 1711 CA PHE A 242 -17.992 16.100 -28.794 1.00 69.16 C ATOM 1712 C PHE A 242 -18.013 14.592 -29.036 1.00 67.55 C ATOM 1713 O PHE A 242 -18.935 13.909 -28.596 1.00 66.94 O ATOM 1714 CB PHE A 242 -18.425 16.844 -30.055 1.00 71.97 C ATOM 1715 CG PHE A 242 -19.811 16.503 -30.511 1.00 75.71 C ATOM 1716 CD1 PHE A 242 -20.915 17.149 -29.961 1.00 76.36 C ATOM 1717 CD2 PHE A 242 -20.016 15.538 -31.493 1.00 74.82 C ATOM 1718 CE1 PHE A 242 -22.201 16.837 -30.382 1.00 75.63 C ATOM 1719 CE2 PHE A 242 -21.299 15.217 -31.917 1.00 74.77 C ATOM 1720 CZ PHE A 242 -22.392 15.868 -31.363 1.00 74.80 C ATOM 1721 N ALA A 243 -16.994 14.086 -29.731 1.00 65.32 N ATOM 1722 CA ALA A 243 -16.858 12.653 -29.985 1.00 66.71 C ATOM 1723 C ALA A 243 -16.574 11.875 -28.703 1.00 67.71 C ATOM 1724 O ALA A 243 -17.054 10.756 -28.526 1.00 66.23 O ATOM 1725 CB ALA A 243 -15.772 12.395 -31.010 1.00 65.77 C ATOM 1726 N LEU A 244 -15.793 12.478 -27.813 1.00 71.10 N ATOM 1727 CA LEU A 244 -15.470 11.869 -26.527 1.00 73.53 C ATOM 1728 C LEU A 244 -16.711 11.775 -25.644 1.00 73.32 C ATOM 1729 O LEU A 244 -16.931 10.766 -24.977 1.00 74.90 O ATOM 1730 CB LEU A 244 -14.394 12.687 -25.816 1.00 75.58 C ATOM 1731 CG LEU A 244 -13.405 11.943 -24.924 1.00 77.16 C ATOM 1732 CD1 LEU A 244 -12.138 11.625 -25.715 1.00 76.73 C ATOM 1733 CD2 LEU A 244 -13.079 12.792 -23.702 1.00 77.90 C ATOM 1734 N CYS A 245 -17.520 12.833 -25.659 1.00 72.17 N ATOM 1735 CA CYS A 245 -18.714 12.925 -24.822 1.00 71.95 C ATOM 1736 C CYS A 245 -19.863 12.046 -25.306 1.00 69.34 C ATOM 1737 O CYS A 245 -20.524 11.389 -24.503 1.00 67.56 O ATOM 1738 CB CYS A 245 -19.196 14.378 -24.726 1.00 75.40 C ATOM 1739 SG CYS A 245 -18.154 15.488 -23.731 1.00 77.39 S ATOM 1740 N TRP A 246 -20.085 12.027 -26.618 1.00 68.88 N ATOM 1741 CA TRP A 246 -21.296 11.425 -27.185 1.00 65.84 C ATOM 1742 C TRP A 246 -21.194 9.993 -27.727 1.00 64.93 C ATOM 1743 O TRP A 246 -22.149 9.232 -27.610 1.00 66.68 O ATOM 1744 CB TRP A 246 -21.904 12.349 -28.237 1.00 60.96 C ATOM 1745 CG TRP A 246 -22.636 13.521 -27.644 1.00 59.45 C ATOM 1746 CD1 TRP A 246 -22.260 14.831 -27.690 1.00 58.08 C ATOM 1747 CD2 TRP A 246 -23.874 13.485 -26.920 1.00 57.09 C ATOM 1748 NE1 TRP A 246 -23.191 15.614 -27.050 1.00 56.21 N ATOM 1749 CE2 TRP A 246 -24.188 14.812 -26.564 1.00 55.41 C ATOM 1750 CE3 TRP A 246 -24.750 12.459 -26.543 1.00 58.67 C ATOM 1751 CZ2 TRP A 246 -25.336 15.141 -25.847 1.00 56.91 C ATOM 1752 CZ3 TRP A 246 -25.892 12.788 -25.827 1.00 58.81 C ATOM 1753 CH2 TRP A 246 -26.173 14.119 -25.485 1.00 58.62 C ATOM 1754 N LEU A 247 -20.057 9.625 -28.312 1.00 64.28 N ATOM 1755 CA LEU A 247 -19.923 8.302 -28.938 1.00 65.45 C ATOM 1756 C LEU A 247 -20.045 7.086 -28.004 1.00 67.49 C ATOM 1757 O LEU A 247 -20.765 6.144 -28.343 1.00 71.45 O ATOM 1758 CB LEU A 247 -18.660 8.202 -29.800 1.00 64.38 C ATOM 1759 CG LEU A 247 -18.589 9.087 -31.049 1.00 66.69 C ATOM 1760 CD1 LEU A 247 -17.217 8.966 -31.692 1.00 66.40 C ATOM 1761 CD2 LEU A 247 -19.690 8.764 -32.060 1.00 66.11 C ATOM 1762 N PRO A 248 -19.362 7.092 -26.833 1.00 67.15 N ATOM 1763 CA PRO A 248 -19.424 5.893 -25.981 1.00 64.79 C ATOM 1764 C PRO A 248 -20.854 5.403 -25.714 1.00 62.95 C ATOM 1765 O PRO A 248 -21.159 4.235 -25.971 1.00 61.41 O ATOM 1766 CB PRO A 248 -18.749 6.351 -24.683 1.00 63.35 C ATOM 1767 CG PRO A 248 -17.810 7.406 -25.115 1.00 62.75 C ATOM 1768 CD PRO A 248 -18.518 8.137 -26.220 1.00 65.92 C ATOM 1769 N LEU A 249 -21.721 6.296 -25.236 1.00 61.56 N ATOM 1770 CA LEU A 249 -23.120 5.956 -24.963 1.00 60.88 C ATOM 1771 C LEU A 249 -23.824 5.402 -26.201 1.00 63.24 C ATOM 1772 O LEU A 249 -24.567 4.417 -26.116 1.00 64.04 O ATOM 1773 CB LEU A 249 -23.875 7.169 -24.405 1.00 56.85 C ATOM 1774 CG LEU A 249 -25.360 7.064 -24.045 1.00 57.48 C ATOM 1775 CD1 LEU A 249 -25.692 5.835 -23.194 1.00 56.72 C ATOM 1776 CD2 LEU A 249 -25.818 8.336 -23.341 1.00 58.28 C ATOM 1777 N HIS A 250 -23.576 6.026 -27.349 1.00 62.35 N ATOM 1778 CA HIS A 250 -24.216 5.598 -28.585 1.00 63.47 C ATOM 1779 C HIS A 250 -23.681 4.266 -29.093 1.00 63.43 C ATOM 1780 O HIS A 250 -24.455 3.431 -29.544 1.00 63.68 O ATOM 1781 CB HIS A 250 -24.144 6.686 -29.647 1.00 63.62 C ATOM 1782 CG HIS A 250 -25.125 7.794 -29.423 1.00 62.55 C ATOM 1783 ND1 HIS A 250 -26.464 7.668 -29.717 1.00 61.11 N ATOM 1784 CD2 HIS A 250 -24.968 9.036 -28.909 1.00 62.72 C ATOM 1785 CE1 HIS A 250 -27.089 8.788 -29.406 1.00 62.87 C ATOM 1786 NE2 HIS A 250 -26.205 9.634 -28.911 1.00 63.58 N ATOM 1787 N ILE A 251 -22.369 4.067 -28.995 1.00 64.41 N ATOM 1788 CA ILE A 251 -21.762 2.772 -29.304 1.00 64.45 C ATOM 1789 C ILE A 251 -22.354 1.687 -28.400 1.00 64.81 C ATOM 1790 O ILE A 251 -22.753 0.628 -28.881 1.00 67.91 O ATOM 1791 CB ILE A 251 -20.218 2.804 -29.181 1.00 65.93 C ATOM 1792 CG1 ILE A 251 -19.613 3.687 -30.276 1.00 65.06 C ATOM 1793 CG2 ILE A 251 -19.628 1.384 -29.257 1.00 66.49 C ATOM 1794 CD1 ILE A 251 -18.197 4.160 -29.975 1.00 66.89 C ATOM 1795 N ILE A 252 -22.430 1.955 -27.099 1.00 63.67 N ATOM 1796 CA ILE A 252 -23.069 1.013 -26.181 1.00 65.87 C ATOM 1797 C ILE A 252 -24.493 0.690 -26.660 1.00 68.52 C ATOM 1798 O ILE A 252 -24.884 -0.481 -26.729 1.00 67.16 O ATOM 1799 CB ILE A 252 -23.062 1.519 -24.724 1.00 63.43 C ATOM 1800 CG1 ILE A 252 -21.628 1.536 -24.187 1.00 64.12 C ATOM 1801 CG2 ILE A 252 -23.906 0.610 -23.846 1.00 63.77 C ATOM 1802 CD1 ILE A 252 -21.396 2.473 -23.014 1.00 61.28 C ATOM 1803 N ASN A 253 -25.244 1.733 -27.015 1.00 70.60 N ATOM 1804 CA ASN A 253 -26.577 1.580 -27.601 1.00 68.49 C ATOM 1805 C ASN A 253 -26.590 0.643 -28.802 1.00 67.32 C ATOM 1806 O ASN A 253 -27.449 -0.234 -28.900 1.00 64.83 O ATOM 1807 CB ASN A 253 -27.155 2.941 -27.995 1.00 68.56 C ATOM 1808 CG ASN A 253 -27.947 3.593 -26.878 1.00 68.58 C ATOM 1809 OD1 ASN A 253 -27.916 3.152 -25.733 1.00 69.90 O ATOM 1810 ND2 ASN A 253 -28.671 4.651 -27.215 1.00 69.64 N ATOM 1811 N CYS A 254 -25.627 0.827 -29.705 1.00 68.08 N ATOM 1812 CA CYS A 254 -25.481 -0.034 -30.877 1.00 68.22 C ATOM 1813 C CYS A 254 -25.209 -1.472 -30.471 1.00 70.62 C ATOM 1814 O CYS A 254 -25.846 -2.391 -30.987 1.00 71.60 O ATOM 1815 CB CYS A 254 -24.386 0.487 -31.801 1.00 65.20 C ATOM 1816 SG CYS A 254 -24.825 2.064 -32.556 1.00 70.18 S ATOM 1817 N PHE A 255 -24.285 -1.655 -29.526 1.00 75.21 N ATOM 1818 CA PHE A 255 -23.995 -2.974 -28.960 1.00 78.88 C ATOM 1819 C PHE A 255 -25.265 -3.639 -28.425 1.00 78.44 C ATOM 1820 O PHE A 255 -25.558 -4.786 -28.759 1.00 81.79 O ATOM 1821 CB PHE A 255 -22.932 -2.879 -27.857 1.00 82.55 C ATOM 1822 CG PHE A 255 -22.767 -4.147 -27.062 1.00 88.10 C ATOM 1823 CD1 PHE A 255 -21.899 -5.145 -27.492 1.00 91.38 C ATOM 1824 CD2 PHE A 255 -23.487 -4.346 -25.880 1.00 92.91 C ATOM 1825 CE1 PHE A 255 -21.747 -6.324 -26.758 1.00 96.67 C ATOM 1826 CE2 PHE A 255 -23.346 -5.520 -25.139 1.00 96.02 C ATOM 1827 CZ PHE A 255 -22.471 -6.510 -25.577 1.00 99.26 C ATOM 1828 N THR A 256 -26.011 -2.907 -27.600 1.00 75.53 N ATOM 1829 CA THR A 256 -27.259 -3.399 -27.021 1.00 74.07 C ATOM 1830 C THR A 256 -28.265 -3.793 -28.102 1.00 76.22 C ATOM 1831 O THR A 256 -28.915 -4.836 -27.997 1.00 75.95 O ATOM 1832 CB THR A 256 -27.882 -2.345 -26.083 1.00 72.14 C ATOM 1833 OG1 THR A 256 -26.882 -1.883 -25.168 1.00 74.36 O ATOM 1834 CG2 THR A 256 -29.059 -2.924 -25.300 1.00 68.87 C ATOM 1835 N PHE A 257 -28.374 -2.961 -29.138 1.00 76.89 N ATOM 1836 CA PHE A 257 -29.320 -3.188 -30.229 1.00 77.32 C ATOM 1837 C PHE A 257 -28.907 -4.337 -31.146 1.00 81.88 C ATOM 1838 O PHE A 257 -29.759 -5.098 -31.606 1.00 81.84 O ATOM 1839 CB PHE A 257 -29.511 -1.910 -31.044 1.00 75.35 C ATOM 1840 CG PHE A 257 -30.506 -2.040 -32.163 1.00 72.14 C ATOM 1841 CD1 PHE A 257 -31.864 -2.187 -31.893 1.00 70.00 C ATOM 1842 CD2 PHE A 257 -30.085 -2.012 -33.488 1.00 71.93 C ATOM 1843 CE1 PHE A 257 -32.788 -2.307 -32.922 1.00 68.17 C ATOM 1844 CE2 PHE A 257 -31.002 -2.131 -34.527 1.00 70.80 C ATOM 1845 CZ PHE A 257 -32.359 -2.279 -34.241 1.00 69.00 C ATOM 1846 N PHE A 258 -27.606 -4.458 -31.407 1.00 85.25 N ATOM 1847 CA PHE A 258 -27.102 -5.487 -32.315 1.00 88.82 C ATOM 1848 C PHE A 258 -26.661 -6.776 -31.623 1.00 98.16 C ATOM 1849 O PHE A 258 -26.364 -7.766 -32.292 1.00103.74 O ATOM 1850 CB PHE A 258 -25.997 -4.933 -33.221 1.00 85.16 C ATOM 1851 CG PHE A 258 -26.490 -3.932 -34.230 1.00 84.25 C ATOM 1852 CD1 PHE A 258 -27.544 -4.244 -35.085 1.00 83.02 C ATOM 1853 CD2 PHE A 258 -25.915 -2.671 -34.314 1.00 84.06 C ATOM 1854 CE1 PHE A 258 -28.008 -3.322 -36.012 1.00 81.65 C ATOM 1855 CE2 PHE A 258 -26.374 -1.742 -35.239 1.00 85.01 C ATOM 1856 CZ PHE A 258 -27.422 -2.070 -36.091 1.00 84.21 C ATOM 1857 N CYS A 259 -26.620 -6.768 -30.293 1.00106.88 N ATOM 1858 CA CYS A 259 -26.426 -8.004 -29.535 1.00112.82 C ATOM 1859 C CYS A 259 -27.503 -8.154 -28.462 1.00116.56 C ATOM 1860 O CYS A 259 -27.271 -7.829 -27.294 1.00116.21 O ATOM 1861 CB CYS A 259 -25.022 -8.097 -28.925 1.00116.33 C ATOM 1862 SG CYS A 259 -24.531 -9.817 -28.617 1.00133.07 S ATOM 1863 N PRO A 260 -28.693 -8.643 -28.860 1.00121.39 N ATOM 1864 CA PRO A 260 -29.791 -8.804 -27.905 1.00126.90 C ATOM 1865 C PRO A 260 -29.630 -10.048 -27.027 1.00131.35 C ATOM 1866 O PRO A 260 -30.269 -10.149 -25.976 1.00132.92 O ATOM 1867 CB PRO A 260 -31.023 -8.922 -28.806 1.00126.28 C ATOM 1868 CG PRO A 260 -30.509 -9.474 -30.090 1.00124.21 C ATOM 1869 CD PRO A 260 -29.067 -9.072 -30.222 1.00120.18 C ATOM 1870 N ASP A 261 -28.777 -10.975 -27.463 1.00132.92 N ATOM 1871 CA ASP A 261 -28.502 -12.208 -26.724 1.00134.26 C ATOM 1872 C ASP A 261 -27.291 -12.080 -25.800 1.00130.62 C ATOM 1873 O ASP A 261 -27.090 -12.913 -24.912 1.00133.97 O ATOM 1874 CB ASP A 261 -28.320 -13.385 -27.689 1.00140.70 C ATOM 1875 CG ASP A 261 -29.627 -13.824 -28.337 1.00145.09 C ATOM 1876 OD1 ASP A 261 -30.702 -13.670 -27.711 1.00145.93 O ATOM 1877 OD2 ASP A 261 -29.575 -14.336 -29.475 1.00145.17 O1- ATOM 1878 N CYS A 262 -26.485 -11.041 -26.020 1.00124.32 N ATOM 1879 CA CYS A 262 -25.410 -10.678 -25.102 1.00119.74 C ATOM 1880 C CYS A 262 -25.987 -10.305 -23.748 1.00115.67 C ATOM 1881 O CYS A 262 -27.110 -9.800 -23.662 1.00116.41 O ATOM 1882 CB CYS A 262 -24.641 -9.463 -25.623 1.00124.00 C ATOM 1883 SG CYS A 262 -23.430 -9.780 -26.907 1.00129.47 S ATOM 1884 N SER A 263 -25.218 -10.553 -22.694 1.00110.97 N ATOM 1885 CA SER A 263 -25.500 -9.946 -21.404 1.00104.42 C ATOM 1886 C SER A 263 -25.334 -8.441 -21.588 1.00 98.70 C ATOM 1887 O SER A 263 -24.395 -7.991 -22.254 1.00 98.94 O ATOM 1888 CB SER A 263 -24.554 -10.478 -20.324 1.00104.29 C ATOM 1889 OG SER A 263 -23.200 -10.378 -20.730 1.00109.29 O ATOM 1890 N HIS A 264 -26.264 -7.673 -21.029 1.00 92.04 N ATOM 1891 CA HIS A 264 -26.265 -6.220 -21.175 1.00 88.85 C ATOM 1892 C HIS A 264 -24.960 -5.606 -20.679 1.00 88.47 C ATOM 1893 O HIS A 264 -24.339 -6.122 -19.747 1.00 95.54 O ATOM 1894 CB HIS A 264 -27.442 -5.614 -20.413 1.00 86.31 C ATOM 1895 CG HIS A 264 -27.833 -4.252 -20.892 1.00 86.64 C ATOM 1896 ND1 HIS A 264 -27.089 -3.125 -20.624 1.00 89.65 N ATOM 1897 CD2 HIS A 264 -28.893 -3.836 -21.624 1.00 88.69 C ATOM 1898 CE1 HIS A 264 -27.668 -2.074 -21.176 1.00 90.81 C ATOM 1899 NE2 HIS A 264 -28.769 -2.477 -21.784 1.00 87.45 N ATOM 1900 N ALA A 265 -24.540 -4.516 -21.315 1.00 86.06 N ATOM 1901 CA ALA A 265 -23.402 -3.740 -20.835 1.00 85.58 C ATOM 1902 C ALA A 265 -23.651 -3.278 -19.394 1.00 86.85 C ATOM 1903 O ALA A 265 -24.740 -2.789 -19.080 1.00 85.54 O ATOM 1904 CB ALA A 265 -23.144 -2.550 -21.747 1.00 86.11 C ATOM 1905 N PRO A 266 -22.646 -3.452 -18.512 1.00 89.71 N ATOM 1906 CA PRO A 266 -22.704 -3.112 -17.084 1.00 88.28 C ATOM 1907 C PRO A 266 -23.282 -1.734 -16.771 1.00 85.16 C ATOM 1908 O PRO A 266 -23.016 -0.768 -17.484 1.00 84.02 O ATOM 1909 CB PRO A 266 -21.229 -3.171 -16.647 1.00 90.38 C ATOM 1910 CG PRO A 266 -20.423 -3.345 -17.913 1.00 90.88 C ATOM 1911 CD PRO A 266 -21.341 -4.039 -18.858 1.00 90.99 C ATOM 1912 N LEU A 267 -24.051 -1.662 -15.688 1.00 85.60 N ATOM 1913 CA LEU A 267 -24.717 -0.433 -15.256 1.00 86.13 C ATOM 1914 C LEU A 267 -23.758 0.689 -14.826 1.00 86.36 C ATOM 1915 O LEU A 267 -24.110 1.869 -14.911 1.00 87.21 O ATOM 1916 CB LEU A 267 -25.720 -0.748 -14.139 1.00 87.20 C ATOM 1917 CG LEU A 267 -26.588 0.352 -13.518 1.00 89.70 C ATOM 1918 CD1 LEU A 267 -27.342 1.161 -14.569 1.00 90.74 C ATOM 1919 CD2 LEU A 267 -27.554 -0.255 -12.513 1.00 90.55 C ATOM 1920 N TRP A 268 -22.560 0.332 -14.365 1.00 85.00 N ATOM 1921 CA TRP A 268 -21.554 1.348 -14.045 1.00 84.22 C ATOM 1922 C TRP A 268 -21.111 2.034 -15.333 1.00 84.35 C ATOM 1923 O TRP A 268 -20.933 3.256 -15.365 1.00 83.25 O ATOM 1924 CB TRP A 268 -20.356 0.763 -13.271 1.00 83.54 C ATOM 1925 CG TRP A 268 -19.451 -0.126 -14.083 1.00 84.29 C ATOM 1926 CD1 TRP A 268 -19.498 -1.488 -14.163 1.00 83.67 C ATOM 1927 CD2 TRP A 268 -18.365 0.288 -14.927 1.00 85.42 C ATOM 1928 NE1 TRP A 268 -18.514 -1.949 -15.006 1.00 84.65 N ATOM 1929 CE2 TRP A 268 -17.807 -0.881 -15.492 1.00 85.15 C ATOM 1930 CE3 TRP A 268 -17.817 1.535 -15.269 1.00 85.83 C ATOM 1931 CZ2 TRP A 268 -16.722 -0.843 -16.378 1.00 86.11 C ATOM 1932 CZ3 TRP A 268 -16.738 1.572 -16.153 1.00 85.59 C ATOM 1933 CH2 TRP A 268 -16.203 0.389 -16.694 1.00 85.96 C ATOM 1934 N LEU A 269 -20.960 1.234 -16.392 1.00 83.26 N ATOM 1935 CA LEU A 269 -20.577 1.726 -17.713 1.00 80.59 C ATOM 1936 C LEU A 269 -21.713 2.545 -18.311 1.00 80.25 C ATOM 1937 O LEU A 269 -21.475 3.558 -18.970 1.00 79.86 O ATOM 1938 CB LEU A 269 -20.208 0.560 -18.635 1.00 79.47 C ATOM 1939 CG LEU A 269 -19.674 0.872 -20.036 1.00 78.49 C ATOM 1940 CD1 LEU A 269 -18.279 1.488 -19.982 1.00 76.28 C ATOM 1941 CD2 LEU A 269 -19.677 -0.387 -20.898 1.00 78.88 C ATOM 1942 N MET A 270 -22.946 2.102 -18.069 1.00 79.04 N ATOM 1943 CA MET A 270 -24.123 2.864 -18.455 1.00 81.43 C ATOM 1944 C MET A 270 -24.056 4.236 -17.798 1.00 84.31 C ATOM 1945 O MET A 270 -24.085 5.263 -18.484 1.00 84.05 O ATOM 1946 CB MET A 270 -25.412 2.134 -18.056 1.00 83.02 C ATOM 1947 CG MET A 270 -25.687 0.829 -18.814 1.00 84.84 C ATOM 1948 SD MET A 270 -25.583 0.949 -20.619 1.00 86.44 S ATOM 1949 CE MET A 270 -26.814 2.202 -20.980 1.00 85.58 C ATOM 1950 N TYR A 271 -23.928 4.236 -16.470 1.00 87.03 N ATOM 1951 CA TYR A 271 -23.819 5.461 -15.679 1.00 88.33 C ATOM 1952 C TYR A 271 -22.667 6.357 -16.131 1.00 82.64 C ATOM 1953 O TYR A 271 -22.818 7.576 -16.197 1.00 77.08 O ATOM 1954 CB TYR A 271 -23.672 5.134 -14.188 1.00 96.38 C ATOM 1955 CG TYR A 271 -24.945 4.661 -13.515 1.00102.57 C ATOM 1956 CD1 TYR A 271 -26.201 5.088 -13.957 1.00106.08 C ATOM 1957 CD2 TYR A 271 -24.893 3.806 -12.417 1.00106.26 C ATOM 1958 CE1 TYR A 271 -27.371 4.661 -13.331 1.00108.35 C ATOM 1959 CE2 TYR A 271 -26.057 3.374 -11.783 1.00110.65 C ATOM 1960 CZ TYR A 271 -27.291 3.804 -12.246 1.00108.90 C ATOM 1961 OH TYR A 271 -28.440 3.377 -11.623 1.00107.56 O ATOM 1962 N LEU A 272 -21.527 5.741 -16.437 1.00 79.15 N ATOM 1963 CA LEU A 272 -20.358 6.460 -16.939 1.00 77.55 C ATOM 1964 C LEU A 272 -20.637 7.132 -18.287 1.00 78.57 C ATOM 1965 O LEU A 272 -20.298 8.302 -18.479 1.00 79.73 O ATOM 1966 CB LEU A 272 -19.148 5.520 -17.042 1.00 74.10 C ATOM 1967 CG LEU A 272 -17.855 6.029 -17.691 1.00 74.56 C ATOM 1968 CD1 LEU A 272 -17.294 7.260 -16.979 1.00 75.15 C ATOM 1969 CD2 LEU A 272 -16.815 4.920 -17.742 1.00 72.79 C ATOM 1970 N ALA A 273 -21.262 6.387 -19.202 1.00 76.72 N ATOM 1971 CA ALA A 273 -21.572 6.871 -20.550 1.00 72.21 C ATOM 1972 C ALA A 273 -22.629 7.981 -20.560 1.00 72.38 C ATOM 1973 O ALA A 273 -22.490 8.967 -21.287 1.00 69.56 O ATOM 1974 CB ALA A 273 -22.007 5.723 -21.423 1.00 70.34 C ATOM 1975 N ILE A 274 -23.681 7.809 -19.760 1.00 71.86 N ATOM 1976 CA ILE A 274 -24.729 8.821 -19.608 1.00 70.75 C ATOM 1977 C ILE A 274 -24.153 10.129 -19.052 1.00 73.48 C ATOM 1978 O ILE A 274 -24.424 11.212 -19.577 1.00 75.06 O ATOM 1979 CB ILE A 274 -25.880 8.310 -18.706 1.00 67.11 C ATOM 1980 CG1 ILE A 274 -26.547 7.081 -19.336 1.00 64.55 C ATOM 1981 CG2 ILE A 274 -26.908 9.408 -18.461 1.00 64.92 C ATOM 1982 CD1 ILE A 274 -27.424 6.289 -18.389 1.00 61.78 C ATOM 1983 N VAL A 275 -23.353 10.013 -17.995 1.00 76.75 N ATOM 1984 CA VAL A 275 -22.672 11.161 -17.392 1.00 77.88 C ATOM 1985 C VAL A 275 -21.777 11.844 -18.428 1.00 78.01 C ATOM 1986 O VAL A 275 -21.860 13.060 -18.628 1.00 78.62 O ATOM 1987 CB VAL A 275 -21.870 10.737 -16.125 1.00 76.74 C ATOM 1988 CG1 VAL A 275 -20.740 11.701 -15.817 1.00 77.39 C ATOM 1989 CG2 VAL A 275 -22.795 10.619 -14.935 1.00 76.72 C ATOM 1990 N LEU A 276 -20.954 11.039 -19.100 1.00 77.37 N ATOM 1991 CA LEU A 276 -20.031 11.517 -20.128 1.00 76.50 C ATOM 1992 C LEU A 276 -20.755 12.267 -21.254 1.00 77.05 C ATOM 1993 O LEU A 276 -20.226 13.231 -21.799 1.00 79.19 O ATOM 1994 CB LEU A 276 -19.219 10.344 -20.691 1.00 76.01 C ATOM 1995 CG LEU A 276 -17.794 10.562 -21.207 1.00 78.10 C ATOM 1996 CD1 LEU A 276 -16.822 10.890 -20.082 1.00 77.36 C ATOM 1997 CD2 LEU A 276 -17.323 9.323 -21.945 1.00 78.34 C ATOM 1998 N SER A 277 -21.969 11.832 -21.589 1.00 75.80 N ATOM 1999 CA SER A 277 -22.769 12.501 -22.611 1.00 72.16 C ATOM 2000 C SER A 277 -23.175 13.895 -22.153 1.00 72.42 C ATOM 2001 O SER A 277 -23.189 14.839 -22.945 1.00 68.33 O ATOM 2002 CB SER A 277 -24.005 11.667 -22.968 1.00 70.58 C ATOM 2003 OG SER A 277 -25.027 11.798 -21.997 1.00 68.49 O ATOM 2004 N HIS A 278 -23.484 14.008 -20.862 1.00 77.56 N ATOM 2005 CA HIS A 278 -23.945 15.259 -20.259 1.00 77.56 C ATOM 2006 C HIS A 278 -22.841 16.281 -20.050 1.00 77.29 C ATOM 2007 O HIS A 278 -23.108 17.487 -20.002 1.00 75.13 O ATOM 2008 CB HIS A 278 -24.630 14.976 -18.930 1.00 77.40 C ATOM 2009 CG HIS A 278 -25.902 14.211 -19.070 1.00 80.07 C ATOM 2010 ND1 HIS A 278 -26.139 13.033 -18.397 1.00 81.55 N ATOM 2011 CD2 HIS A 278 -27.001 14.445 -19.823 1.00 81.74 C ATOM 2012 CE1 HIS A 278 -27.338 12.583 -18.718 1.00 84.17 C ATOM 2013 NE2 HIS A 278 -27.880 13.418 -19.586 1.00 85.06 N ATOM 2014 N THR A 279 -21.608 15.794 -19.928 1.00 77.53 N ATOM 2015 CA THR A 279 -20.456 16.662 -19.702 1.00 79.10 C ATOM 2016 C THR A 279 -20.056 17.482 -20.939 1.00 79.76 C ATOM 2017 O THR A 279 -19.138 18.300 -20.880 1.00 82.47 O ATOM 2018 CB THR A 279 -19.249 15.887 -19.115 1.00 79.12 C ATOM 2019 OG1 THR A 279 -18.214 16.811 -18.765 1.00 81.68 O ATOM 2020 CG2 THR A 279 -18.693 14.897 -20.107 1.00 81.02 C ATOM 2021 N ASN A 280 -20.757 17.269 -22.049 1.00 79.02 N ATOM 2022 CA ASN A 280 -20.579 18.091 -23.240 1.00 78.67 C ATOM 2023 C ASN A 280 -21.063 19.521 -23.018 1.00 79.93 C ATOM 2024 O ASN A 280 -20.535 20.465 -23.608 1.00 80.09 O ATOM 2025 CB ASN A 280 -21.317 17.474 -24.431 1.00 76.26 C ATOM 2026 CG ASN A 280 -21.050 18.214 -25.726 1.00 76.93 C ATOM 2027 OD1 ASN A 280 -19.913 18.275 -26.194 1.00 76.70 O ATOM 2028 ND2 ASN A 280 -22.099 18.789 -26.309 1.00 76.81 N ATOM 2029 N SER A 281 -22.067 19.667 -22.158 1.00 80.83 N ATOM 2030 CA SER A 281 -22.714 20.954 -21.915 1.00 84.83 C ATOM 2031 C SER A 281 -21.879 21.918 -21.064 1.00 86.04 C ATOM 2032 O SER A 281 -22.075 23.135 -21.117 1.00 83.83 O ATOM 2033 CB SER A 281 -24.086 20.729 -21.283 1.00 84.45 C ATOM 2034 OG SER A 281 -24.935 20.057 -22.192 1.00 83.35 O ATOM 2035 N VAL A 282 -20.956 21.369 -20.281 1.00 85.08 N ATOM 2036 CA VAL A 282 -20.058 22.186 -19.475 1.00 86.64 C ATOM 2037 C VAL A 282 -18.863 22.653 -20.305 1.00 87.83 C ATOM 2038 O VAL A 282 -18.456 23.811 -20.208 1.00 93.33 O ATOM 2039 CB VAL A 282 -19.630 21.465 -18.157 1.00 88.18 C ATOM 2040 CG1 VAL A 282 -19.453 19.975 -18.373 1.00 85.58 C ATOM 2041 CG2 VAL A 282 -18.372 22.085 -17.549 1.00 87.07 C ATOM 2042 N VAL A 283 -18.324 21.766 -21.136 1.00 85.62 N ATOM 2043 CA VAL A 283 -17.182 22.116 -21.986 1.00 83.06 C ATOM 2044 C VAL A 283 -17.577 22.852 -23.280 1.00 83.53 C ATOM 2045 O VAL A 283 -16.916 23.813 -23.675 1.00 88.15 O ATOM 2046 CB VAL A 283 -16.261 20.899 -22.277 1.00 81.68 C ATOM 2047 CG1 VAL A 283 -15.594 20.428 -20.996 1.00 80.68 C ATOM 2048 CG2 VAL A 283 -17.028 19.752 -22.939 1.00 82.36 C ATOM 2049 N ASN A 284 -18.645 22.397 -23.931 1.00 80.25 N ATOM 2050 CA ASN A 284 -19.155 23.054 -25.130 1.00 80.44 C ATOM 2051 C ASN A 284 -20.389 23.878 -24.798 1.00 81.02 C ATOM 2052 O ASN A 284 -21.321 23.364 -24.178 1.00 85.03 O ATOM 2053 CB ASN A 284 -19.493 22.031 -26.220 1.00 82.92 C ATOM 2054 CG ASN A 284 -18.260 21.495 -26.934 1.00 82.65 C ATOM 2055 OD1 ASN A 284 -17.422 22.259 -27.419 1.00 87.43 O ATOM 2056 ND2 ASN A 284 -18.155 20.173 -27.017 1.00 77.60 N ATOM 2057 N PRO A 285 -20.400 25.160 -25.203 1.00 79.48 N ATOM 2058 CA PRO A 285 -19.309 25.796 -25.921 1.00 81.43 C ATOM 2059 C PRO A 285 -18.401 26.627 -25.007 1.00 81.93 C ATOM 2060 O PRO A 285 -17.800 27.597 -25.474 1.00 82.47 O ATOM 2061 CB PRO A 285 -20.054 26.729 -26.874 1.00 81.00 C ATOM 2062 CG PRO A 285 -21.238 27.190 -26.057 1.00 79.67 C ATOM 2063 CD PRO A 285 -21.545 26.078 -25.061 1.00 78.57 C ATOM 2064 N PHE A 286 -18.304 26.261 -23.728 1.00 80.17 N ATOM 2065 CA PHE A 286 -17.535 27.069 -22.781 1.00 82.24 C ATOM 2066 C PHE A 286 -16.108 27.302 -23.263 1.00 81.85 C ATOM 2067 O PHE A 286 -15.701 28.450 -23.464 1.00 82.04 O ATOM 2068 CB PHE A 286 -17.531 26.472 -21.368 1.00 84.19 C ATOM 2069 CG PHE A 286 -16.773 27.307 -20.365 1.00 86.55 C ATOM 2070 CD1 PHE A 286 -17.360 28.428 -19.788 1.00 87.40 C ATOM 2071 CD2 PHE A 286 -15.463 26.986 -20.015 1.00 89.67 C ATOM 2072 CE1 PHE A 286 -16.658 29.213 -18.870 1.00 88.47 C ATOM 2073 CE2 PHE A 286 -14.752 27.766 -19.096 1.00 86.97 C ATOM 2074 CZ PHE A 286 -15.353 28.879 -18.524 1.00 86.00 C ATOM 2075 N ILE A 287 -15.368 26.210 -23.459 1.00 79.59 N ATOM 2076 CA ILE A 287 -13.954 26.264 -23.848 1.00 75.22 C ATOM 2077 C ILE A 287 -13.710 27.066 -25.136 1.00 77.93 C ATOM 2078 O ILE A 287 -12.708 27.772 -25.245 1.00 82.03 O ATOM 2079 CB ILE A 287 -13.330 24.853 -23.955 1.00 71.06 C ATOM 2080 CG1 ILE A 287 -13.457 24.113 -22.614 1.00 70.01 C ATOM 2081 CG2 ILE A 287 -11.868 24.943 -24.414 1.00 71.79 C ATOM 2082 CD1 ILE A 287 -12.841 22.709 -22.578 1.00 65.45 C ATOM 2083 N TYR A 288 -14.624 26.965 -26.098 1.00 79.62 N ATOM 2084 CA TYR A 288 -14.521 27.750 -27.328 1.00 81.58 C ATOM 2085 C TYR A 288 -14.473 29.236 -26.992 1.00 86.61 C ATOM 2086 O TYR A 288 -13.659 29.973 -27.548 1.00 91.00 O ATOM 2087 CB TYR A 288 -15.679 27.438 -28.291 1.00 76.67 C ATOM 2088 CG TYR A 288 -15.835 28.413 -29.446 1.00 70.10 C ATOM 2089 CD1 TYR A 288 -15.020 28.333 -30.576 1.00 69.40 C ATOM 2090 CD2 TYR A 288 -16.807 29.409 -29.408 1.00 70.31 C ATOM 2091 CE1 TYR A 288 -15.167 29.228 -31.640 1.00 68.22 C ATOM 2092 CE2 TYR A 288 -16.964 30.307 -30.463 1.00 69.58 C ATOM 2093 CZ TYR A 288 -16.141 30.213 -31.571 1.00 68.78 C ATOM 2094 OH TYR A 288 -16.304 31.109 -32.601 1.00 68.22 O ATOM 2095 N ALA A 289 -15.339 29.658 -26.070 1.00 91.65 N ATOM 2096 CA ALA A 289 -15.423 31.055 -25.648 1.00 93.97 C ATOM 2097 C ALA A 289 -14.200 31.457 -24.823 1.00 94.16 C ATOM 2098 O ALA A 289 -13.643 32.541 -25.019 1.00 94.94 O ATOM 2099 CB ALA A 289 -16.713 31.302 -24.870 1.00 91.96 C ATOM 2100 N TYR A 290 -13.781 30.567 -23.924 1.00 92.10 N ATOM 2101 CA TYR A 290 -12.585 30.762 -23.100 1.00 96.75 C ATOM 2102 C TYR A 290 -11.329 30.995 -23.947 1.00 96.24 C ATOM 2103 O TYR A 290 -10.324 31.512 -23.458 1.00 98.64 O ATOM 2104 CB TYR A 290 -12.389 29.555 -22.172 1.00102.73 C ATOM 2105 CG TYR A 290 -11.257 29.685 -21.169 1.00110.56 C ATOM 2106 CD1 TYR A 290 -11.407 30.450 -20.009 1.00111.64 C ATOM 2107 CD2 TYR A 290 -10.043 29.025 -21.370 1.00114.02 C ATOM 2108 CE1 TYR A 290 -10.374 30.564 -19.085 1.00114.83 C ATOM 2109 CE2 TYR A 290 -9.004 29.133 -20.450 1.00115.15 C ATOM 2110 CZ TYR A 290 -9.177 29.902 -19.313 1.00116.15 C ATOM 2111 OH TYR A 290 -8.153 30.010 -18.402 1.00121.17 O ATOM 2112 N ARG A 291 -11.404 30.619 -25.220 1.00 93.95 N ATOM 2113 CA ARG A 291 -10.294 30.783 -26.148 1.00 90.43 C ATOM 2114 C ARG A 291 -10.406 32.065 -26.979 1.00 92.64 C ATOM 2115 O ARG A 291 -9.673 32.250 -27.953 1.00 92.41 O ATOM 2116 CB ARG A 291 -10.163 29.551 -27.043 1.00 86.54 C ATOM 2117 CG ARG A 291 -9.509 28.367 -26.356 1.00 83.49 C ATOM 2118 CD ARG A 291 -9.457 27.141 -27.259 1.00 86.29 C ATOM 2119 NE ARG A 291 -8.876 27.410 -28.578 1.00 85.75 N ATOM 2120 CZ ARG A 291 -7.570 27.452 -28.841 1.00 86.10 C ATOM 2121 NH1 ARG A 291 -6.675 27.252 -27.878 1.00 87.83 N ATOM 2122 NH2 ARG A 291 -7.156 27.698 -30.075 1.00 82.94 N ATOM 2123 N ILE A 292 -11.333 32.938 -26.602 1.00 95.97 N ATOM 2124 CA ILE A 292 -11.334 34.303 -27.116 1.00103.84 C ATOM 2125 C ILE A 292 -10.945 35.214 -25.958 1.00110.99 C ATOM 2126 O ILE A 292 -11.536 35.146 -24.875 1.00112.82 O ATOM 2127 CB ILE A 292 -12.692 34.728 -27.747 1.00102.03 C ATOM 2128 CG1 ILE A 292 -13.003 33.898 -28.995 1.00102.55 C ATOM 2129 CG2 ILE A 292 -12.677 36.203 -28.138 1.00102.02 C ATOM 2130 CD1 ILE A 292 -14.022 32.801 -28.775 1.00100.22 C ATOM 2131 N ARG A 293 -9.929 36.042 -26.187 1.00115.78 N ATOM 2132 CA ARG A 293 -9.404 36.935 -25.158 1.00117.22 C ATOM 2133 C ARG A 293 -10.475 37.884 -24.615 1.00115.87 C ATOM 2134 O ARG A 293 -10.616 38.033 -23.396 1.00111.77 O ATOM 2135 CB ARG A 293 -8.180 37.709 -25.673 1.00120.18 C ATOM 2136 CG ARG A 293 -8.358 38.397 -27.031 1.00121.36 C ATOM 2137 CD ARG A 293 -7.255 39.415 -27.301 1.00122.12 C ATOM 2138 NE ARG A 293 -7.410 40.627 -26.496 1.00125.44 N ATOM 2139 CZ ARG A 293 -6.767 40.873 -25.355 1.00128.64 C ATOM 2140 NH1 ARG A 293 -5.905 39.993 -24.856 1.00128.14 N ATOM 2141 NH2 ARG A 293 -6.988 42.007 -24.707 1.00131.69 N ATOM 2142 N GLU A 294 -11.236 38.491 -25.528 1.00113.87 N ATOM 2143 CA GLU A 294 -12.282 39.455 -25.182 1.00114.40 C ATOM 2144 C GLU A 294 -13.282 38.858 -24.188 1.00114.97 C ATOM 2145 O GLU A 294 -13.766 39.552 -23.292 1.00117.87 O ATOM 2146 CB GLU A 294 -12.988 39.953 -26.448 1.00113.19 C ATOM 2147 CG GLU A 294 -13.759 41.269 -26.279 1.00118.47 C ATOM 2148 CD GLU A 294 -12.873 42.512 -26.295 1.00119.55 C ATOM 2149 OE1 GLU A 294 -11.793 42.481 -26.923 1.00121.83 O ATOM 2150 OE2 GLU A 294 -13.271 43.530 -25.686 1.00116.92 O1- ATOM 2151 N PHE A 295 -13.569 37.568 -24.349 1.00113.48 N ATOM 2152 CA PHE A 295 -14.373 36.816 -23.390 1.00113.03 C ATOM 2153 C PHE A 295 -13.620 36.604 -22.081 1.00113.92 C ATOM 2154 O PHE A 295 -14.160 36.854 -21.004 1.00116.11 O ATOM 2155 CB PHE A 295 -14.772 35.452 -23.966 1.00113.23 C ATOM 2156 CG PHE A 295 -16.113 35.436 -24.645 1.00110.57 C ATOM 2157 CD1 PHE A 295 -17.270 35.165 -23.919 1.00109.19 C ATOM 2158 CD2 PHE A 295 -16.219 35.670 -26.012 1.00107.73 C ATOM 2159 CE1 PHE A 295 -18.515 35.142 -24.545 1.00107.93 C ATOM 2160 CE2 PHE A 295 -17.458 35.650 -26.645 1.00106.24 C ATOM 2161 CZ PHE A 295 -18.608 35.386 -25.910 1.00106.19 C ATOM 2162 N ARG A 296 -12.373 36.146 -22.190 1.00114.06 N ATOM 2163 CA ARG A 296 -11.576 35.728 -21.033 1.00112.62 C ATOM 2164 C ARG A 296 -11.275 36.874 -20.068 1.00110.46 C ATOM 2165 O ARG A 296 -11.265 36.678 -18.851 1.00105.37 O ATOM 2166 CB ARG A 296 -10.283 35.056 -21.498 1.00113.60 C ATOM 2167 CG ARG A 296 -9.608 34.173 -20.449 1.00115.21 C ATOM 2168 CD ARG A 296 -8.437 33.386 -21.036 1.00116.52 C ATOM 2169 NE ARG A 296 -7.378 34.255 -21.554 1.00118.60 N ATOM 2170 CZ ARG A 296 -7.182 34.532 -22.842 1.00120.89 C ATOM 2171 NH1 ARG A 296 -7.970 34.010 -23.774 1.00119.91 N ATOM 2172 NH2 ARG A 296 -6.191 35.338 -23.201 1.00124.76 N ATOM 2173 N GLN A 297 -11.029 38.061 -20.620 1.00111.25 N ATOM 2174 CA GLN A 297 -10.857 39.268 -19.814 1.00113.04 C ATOM 2175 C GLN A 297 -12.146 39.579 -19.055 1.00111.77 C ATOM 2176 O GLN A 297 -12.119 39.816 -17.843 1.00111.35 O ATOM 2177 CB GLN A 297 -10.453 40.458 -20.690 1.00116.61 C ATOM 2178 CG GLN A 297 -9.021 40.403 -21.210 1.00116.05 C ATOM 2179 CD GLN A 297 -8.589 41.696 -21.884 1.00118.63 C ATOM 2180 OE1 GLN A 297 -9.355 42.323 -22.620 1.00115.93 O ATOM 2181 NE2 GLN A 297 -7.348 42.096 -21.638 1.00123.53 N ATOM 2182 N THR A 298 -13.266 39.557 -19.781 1.00106.97 N ATOM 2183 CA THR A 298 -14.598 39.749 -19.204 1.00101.34 C ATOM 2184 C THR A 298 -14.908 38.668 -18.166 1.00101.89 C ATOM 2185 O THR A 298 -15.556 38.942 -17.158 1.00100.91 O ATOM 2186 CB THR A 298 -15.694 39.764 -20.297 1.00 99.23 C ATOM 2187 OG1 THR A 298 -15.306 40.641 -21.362 1.00 97.80 O ATOM 2188 CG2 THR A 298 -17.029 40.235 -19.729 1.00100.84 C ATOM 2189 N PHE A 299 -14.433 37.449 -18.415 1.00107.71 N ATOM 2190 CA PHE A 299 -14.601 36.344 -17.474 1.00114.23 C ATOM 2191 C PHE A 299 -13.855 36.594 -16.172 1.00115.89 C ATOM 2192 O PHE A 299 -14.296 36.155 -15.109 1.00114.30 O ATOM 2193 CB PHE A 299 -14.134 35.017 -18.083 1.00121.72 C ATOM 2194 CG PHE A 299 -15.105 34.410 -19.060 1.00125.23 C ATOM 2195 CD1 PHE A 299 -16.477 34.447 -18.824 1.00126.92 C ATOM 2196 CD2 PHE A 299 -14.642 33.770 -20.206 1.00127.03 C ATOM 2197 CE1 PHE A 299 -17.370 33.879 -19.726 1.00127.99 C ATOM 2198 CE2 PHE A 299 -15.530 33.197 -21.114 1.00128.76 C ATOM 2199 CZ PHE A 299 -16.897 33.252 -20.872 1.00128.97 C ATOM 2200 N ARG A 300 -12.720 37.287 -16.262 1.00121.91 N ATOM 2201 CA ARG A 300 -11.952 37.653 -15.075 1.00123.68 C ATOM 2202 C ARG A 300 -12.651 38.753 -14.286 1.00120.78 C ATOM 2203 O ARG A 300 -12.742 38.668 -13.065 1.00115.54 O ATOM 2204 CB ARG A 300 -10.518 38.053 -15.431 1.00129.98 C ATOM 2205 CG ARG A 300 -9.602 36.865 -15.707 1.00134.49 C ATOM 2206 CD ARG A 300 -8.140 37.181 -15.401 1.00136.36 C ATOM 2207 NE ARG A 300 -7.590 38.218 -16.275 1.00138.22 N ATOM 2208 CZ ARG A 300 -7.070 37.995 -17.479 1.00140.14 C ATOM 2209 NH1 ARG A 300 -7.024 36.766 -17.978 1.00139.35 N ATOM 2210 NH2 ARG A 300 -6.597 39.009 -18.191 1.00142.04 N ATOM 2211 N LYS A 301 -13.166 39.761 -14.992 1.00118.77 N ATOM 2212 CA LYS A 301 -13.942 40.847 -14.377 1.00118.83 C ATOM 2213 C LYS A 301 -15.126 40.361 -13.531 1.00124.79 C ATOM 2214 O LYS A 301 -15.538 41.042 -12.591 1.00129.56 O ATOM 2215 CB LYS A 301 -14.455 41.822 -15.441 1.00112.77 C ATOM 2216 CG LYS A 301 -13.382 42.677 -16.096 1.00111.91 C ATOM 2217 CD LYS A 301 -13.970 43.954 -16.701 1.00112.65 C ATOM 2218 CE LYS A 301 -14.816 43.682 -17.943 1.00111.93 C ATOM 2219 NZ LYS A 301 -14.003 43.163 -19.078 1.00111.87 N ATOM 2220 N ILE A 302 -15.667 39.191 -13.872 1.00127.78 N ATOM 2221 CA ILE A 302 -16.827 38.624 -13.172 1.00129.04 C ATOM 2222 C ILE A 302 -16.419 37.764 -11.967 1.00132.35 C ATOM 2223 O ILE A 302 -16.991 37.900 -10.882 1.00131.99 O ATOM 2224 CB ILE A 302 -17.752 37.826 -14.139 1.00127.41 C ATOM 2225 CG1 ILE A 302 -18.306 38.748 -15.234 1.00125.05 C ATOM 2226 CG2 ILE A 302 -18.896 37.149 -13.375 1.00125.22 C ATOM 2227 CD1 ILE A 302 -18.759 38.028 -16.498 1.00123.92 C ATOM 2228 N ILE A 303 -15.434 36.886 -12.160 1.00133.90 N ATOM 2229 CA ILE A 303 -14.938 36.033 -11.074 1.00137.05 C ATOM 2230 C ILE A 303 -14.096 36.850 -10.082 1.00141.48 C ATOM 2231 O ILE A 303 -14.044 36.529 -8.891 1.00144.47 O ATOM 2232 CB ILE A 303 -14.153 34.797 -11.602 1.00136.06 C ATOM 2233 CG1 ILE A 303 -14.968 34.057 -12.670 1.00137.42 C ATOM 2234 CG2 ILE A 303 -13.809 33.838 -10.458 1.00132.45 C ATOM 2235 CD1 ILE A 303 -14.163 33.087 -13.527 1.00138.45 C ATOM 2236 N ARG A 304 -13.458 37.909 -10.582 1.00139.99 N ATOM 2237 CA ARG A 304 -12.722 38.865 -9.748 1.00139.04 C ATOM 2238 C ARG A 304 -13.669 39.566 -8.777 1.00139.15 C ATOM 2239 O ARG A 304 -13.461 39.527 -7.561 1.00137.02 O ATOM 2240 CB ARG A 304 -12.009 39.894 -10.634 1.00137.81 C ATOM 2241 CG ARG A 304 -10.994 40.780 -9.934 1.00134.22 C ATOM 2242 CD ARG A 304 -10.022 41.380 -10.943 1.00133.74 C ATOM 2243 NE ARG A 304 -10.632 42.389 -11.810 1.00134.20 N ATOM 2244 CZ ARG A 304 -10.471 43.706 -11.679 1.00133.66 C ATOM 2245 NH1 ARG A 304 -9.715 44.207 -10.709 1.00131.48 N ATOM 2246 NH2 ARG A 304 -11.072 44.528 -12.528 1.00132.35 N ATOM 2247 N SER A 305 -14.715 40.186 -9.328 1.00136.91 N ATOM 2248 CA SER A 305 -15.741 40.883 -8.549 1.00133.51 C ATOM 2249 C SER A 305 -16.461 39.955 -7.576 1.00133.46 C ATOM 2250 O SER A 305 -17.067 40.411 -6.607 1.00135.34 O ATOM 2251 CB SER A 305 -16.757 41.547 -9.479 1.00130.48 C ATOM 2252 OG SER A 305 -16.136 42.510 -10.310 1.00130.56 O ATOM 2253 N HIS A 306 -16.392 38.655 -7.850 1.00137.65 N ATOM 2254 CA HIS A 306 -16.960 37.638 -6.974 1.00142.81 C ATOM 2255 C HIS A 306 -16.020 37.315 -5.809 1.00147.60 C ATOM 2256 O HIS A 306 -16.461 36.815 -4.775 1.00149.63 O ATOM 2257 CB HIS A 306 -17.293 36.371 -7.769 1.00141.11 C ATOM 2258 CG HIS A 306 -17.929 35.290 -6.949 1.00141.18 C ATOM 2259 ND1 HIS A 306 -19.275 35.271 -6.656 1.00142.35 N ATOM 2260 CD2 HIS A 306 -17.400 34.192 -6.359 1.00142.62 C ATOM 2261 CE1 HIS A 306 -19.549 34.207 -5.922 1.00142.65 C ATOM 2262 NE2 HIS A 306 -18.428 33.535 -5.727 1.00143.89 N ATOM 2263 N VAL A 307 -14.730 37.604 -5.978 1.00152.73 N ATOM 2264 CA VAL A 307 -13.735 37.355 -4.924 1.00159.64 C ATOM 2265 C VAL A 307 -13.525 38.580 -4.024 1.00160.55 C ATOM 2266 O VAL A 307 -13.447 38.450 -2.797 1.00155.19 O ATOM 2267 CB VAL A 307 -12.387 36.834 -5.505 1.00160.71 C ATOM 2268 CG1 VAL A 307 -11.302 36.777 -4.431 1.00160.51 C ATOM 2269 CG2 VAL A 307 -12.575 35.456 -6.127 1.00161.14 C ATOM 2270 N LEU A 308 -13.452 39.765 -4.632 1.00162.56 N ATOM 2271 CA LEU A 308 -13.280 41.014 -3.880 1.00163.51 C ATOM 2272 C LEU A 308 -14.556 41.484 -3.161 1.00166.45 C ATOM 2273 O LEU A 308 -14.589 42.583 -2.598 1.00169.93 O ATOM 2274 CB LEU A 308 -12.684 42.131 -4.763 1.00159.28 C ATOM 2275 CG LEU A 308 -13.322 42.608 -6.076 1.00156.06 C ATOM 2276 CD1 LEU A 308 -14.500 43.551 -5.852 1.00153.10 C ATOM 2277 CD2 LEU A 308 -12.271 43.295 -6.938 1.00154.97 C ATOM 2278 N ARG A 309 -15.593 40.647 -3.176 1.00165.09 N ATOM 2279 CA ARG A 309 -16.852 40.960 -2.497 1.00162.02 C ATOM 2280 C ARG A 309 -17.381 39.821 -1.617 1.00163.11 C ATOM 2281 O ARG A 309 -18.051 40.077 -0.616 1.00170.69 O ATOM 2282 CB ARG A 309 -17.921 41.427 -3.496 1.00160.00 C ATOM 2283 CG ARG A 309 -17.661 42.816 -4.077 1.00160.03 C ATOM 2284 CD ARG A 309 -18.932 43.477 -4.588 1.00162.69 C ATOM 2285 NE ARG A 309 -19.345 42.976 -5.898 1.00164.88 N ATOM 2286 CZ ARG A 309 -19.032 43.547 -7.059 1.00164.17 C ATOM 2287 NH1 ARG A 309 -18.291 44.649 -7.091 1.00163.98 N ATOM 2288 NH2 ARG A 309 -19.462 43.013 -8.194 1.00163.81 N ATOM 2289 N GLN A 310 -17.078 38.575 -1.985 1.00158.34 N ATOM 2290 CA GLN A 310 -17.512 37.409 -1.200 1.00155.58 C ATOM 2291 C GLN A 310 -16.485 36.959 -0.160 1.00153.98 C ATOM 2292 O GLN A 310 -16.774 36.095 0.673 1.00152.69 O ATOM 2293 CB GLN A 310 -17.900 36.238 -2.111 1.00154.28 C ATOM 2294 CG GLN A 310 -19.351 36.260 -2.593 1.00153.56 C ATOM 2295 CD GLN A 310 -20.341 35.739 -1.555 1.00153.13 C ATOM 2296 OE1 GLN A 310 -20.045 34.809 -0.802 1.00149.53 O ATOM 2297 NE2 GLN A 310 -21.529 36.334 -1.524 1.00153.10 N ATOM 2298 N GLN A 311 -15.292 37.544 -0.213 1.00154.72 N ATOM 2299 CA GLN A 311 -14.260 37.283 0.788 1.00156.06 C ATOM 2300 C GLN A 311 -14.055 38.515 1.680 1.00156.67 C ATOM 2301 O GLN A 311 -13.215 38.508 2.585 1.00156.53 O ATOM 2302 CB GLN A 311 -12.954 36.858 0.108 1.00154.72 C ATOM 2303 CG GLN A 311 -12.142 35.831 0.890 1.00150.74 C ATOM 2304 CD GLN A 311 -11.077 35.148 0.046 1.00148.52 C ATOM 2305 OE1 GLN A 311 -11.255 34.936 -1.154 1.00149.81 O ATOM 2306 NE2 GLN A 311 -9.966 34.790 0.677 1.00147.95 N ATOM 2307 N GLU A 312 -14.849 39.557 1.421 1.00156.85 N ATOM 2308 CA GLU A 312 -14.804 40.830 2.157 1.00152.50 C ATOM 2309 C GLU A 312 -15.123 40.722 3.661 1.00148.43 C ATOM 2310 O GLU A 312 -14.443 41.361 4.467 1.00144.93 O ATOM 2311 CB GLU A 312 -15.712 41.874 1.483 1.00152.50 C ATOM 2312 CG GLU A 312 -15.611 43.295 2.041 1.00152.97 C ATOM 2313 CD GLU A 312 -14.461 44.093 1.446 1.00153.95 C ATOM 2314 OE1 GLU A 312 -13.290 43.711 1.654 1.00154.83 O ATOM 2315 OE2 GLU A 312 -14.733 45.106 0.767 1.00153.45 O ATOM 2316 N PRO A 313 -16.156 39.931 4.043 1.00147.96 N ATOM 2317 CA PRO A 313 -16.418 39.702 5.471 1.00147.68 C ATOM 2318 C PRO A 313 -15.215 39.157 6.252 1.00145.71 C ATOM 2319 O PRO A 313 -14.999 39.553 7.399 1.00143.22 O ATOM 2320 CB PRO A 313 -17.550 38.670 5.453 1.00145.60 C ATOM 2321 CG PRO A 313 -18.285 38.967 4.210 1.00143.04 C ATOM 2322 CD PRO A 313 -17.235 39.363 3.208 1.00146.04 C ATOM 2323 N PHE A 314 -14.447 38.266 5.630 1.00146.26 N ATOM 2324 CA PHE A 314 -13.260 37.682 6.257 1.00143.79 C ATOM 2325 C PHE A 314 -12.017 38.563 6.094 1.00140.83 C ATOM 2326 O PHE A 314 -11.085 38.480 6.899 1.00138.22 O ATOM 2327 CB PHE A 314 -13.000 36.274 5.708 1.00144.81 C ATOM 2328 CG PHE A 314 -13.939 35.225 6.248 1.00146.88 C ATOM 2329 CD1 PHE A 314 -15.176 34.999 5.648 1.00146.27 C ATOM 2330 CD2 PHE A 314 -13.583 34.457 7.356 1.00147.43 C ATOM 2331 CE1 PHE A 314 -16.046 34.026 6.146 1.00146.94 C ATOM 2332 CE2 PHE A 314 -14.445 33.481 7.861 1.00145.81 C ATOM 2333 CZ PHE A 314 -15.678 33.266 7.255 1.00147.22 C ATOM 2334 N LYS A 315 -12.014 39.399 5.055 1.00137.82 N ATOM 2335 CA LYS A 315 -10.920 40.341 4.793 1.00135.03 C ATOM 2336 C LYS A 315 -10.878 41.446 5.853 1.00133.42 C ATOM 2337 O LYS A 315 -9.803 41.815 6.333 1.00132.94 O ATOM 2338 CB LYS A 315 -11.062 40.948 3.390 1.00134.63 C ATOM 2339 CG LYS A 315 -9.805 41.626 2.836 1.00135.99 C ATOM 2340 CD LYS A 315 -8.813 40.615 2.263 1.00135.67 C ATOM 2341 CE LYS A 315 -7.667 41.299 1.526 1.00133.04 C ATOM 2342 NZ LYS A 315 -8.090 41.856 0.209 1.00130.50 N ATOM 2343 N ALA A 316 -12.054 41.962 6.207 1.00128.28 N ATOM 2344 CA ALA A 316 -12.193 42.969 7.254 1.00120.47 C ATOM 2345 C ALA A 316 -11.963 42.364 8.639 1.00119.14 C ATOM 2346 O ALA A 316 -11.357 42.998 9.506 1.00118.70 O ATOM 2347 CB ALA A 316 -13.562 43.624 7.176 1.00116.67 C ATOM 2348 N ALA A 317 -12.445 41.136 8.833 1.00116.34 N ATOM 2349 CA ALA A 317 -12.281 40.415 10.098 1.00118.70 C ATOM 2350 C ALA A 317 -10.811 40.173 10.434 1.00120.22 C ATOM 2351 O ALA A 317 -10.415 40.246 11.597 1.00119.23 O ATOM 2352 CB ALA A 317 -13.042 39.096 10.063 1.00118.22 C ATOM 2353 N ALA A 318 -10.011 39.884 9.411 1.00125.31 N ATOM 2354 CA ALA A 318 -8.574 39.704 9.577 1.00125.89 C ATOM 2355 C ALA A 318 -7.895 41.048 9.811 1.00126.93 C ATOM 2356 O ALA A 318 -6.976 41.150 10.625 1.00127.59 O ATOM 2357 CB ALA A 318 -7.979 39.007 8.361 1.00126.64 C ATOM 2358 N ALA A 319 -8.366 42.072 9.098 1.00127.93 N ATOM 2359 CA ALA A 319 -7.824 43.428 9.201 1.00128.57 C ATOM 2360 C ALA A 319 -7.994 44.013 10.600 1.00130.36 C ATOM 2361 O ALA A 319 -7.111 44.715 11.090 1.00131.05 O ATOM 2362 CB ALA A 319 -8.461 44.342 8.159 1.00127.26 C ATOM 2363 N GLU A 320 -9.126 43.715 11.235 1.00130.93 N ATOM 2364 CA GLU A 320 -9.395 44.177 12.595 1.00128.83 C ATOM 2365 C GLU A 320 -8.622 43.384 13.646 1.00125.12 C ATOM 2366 O GLU A 320 -8.104 43.964 14.599 1.00124.74 O ATOM 2367 CB GLU A 320 -10.896 44.156 12.901 1.00134.17 C ATOM 2368 CG GLU A 320 -11.660 45.356 12.341 1.00140.36 C ATOM 2369 CD GLU A 320 -13.057 45.506 12.930 1.00143.50 C ATOM 2370 OE1 GLU A 320 -13.221 45.316 14.155 1.00142.38 O ATOM 2371 OE2 GLU A 320 -13.990 45.837 12.167 1.00147.28 O ATOM 2372 N ASN A 321 -8.544 42.064 13.465 1.00121.84 N ATOM 2373 CA ASN A 321 -7.845 41.180 14.406 1.00120.88 C ATOM 2374 C ASN A 321 -6.359 41.506 14.575 1.00118.50 C ATOM 2375 O ASN A 321 -5.832 41.464 15.689 1.00115.83 O ATOM 2376 CB ASN A 321 -8.025 39.708 14.013 1.00122.69 C ATOM 2377 CG ASN A 321 -9.418 39.176 14.334 1.00126.37 C ATOM 2378 OD1 ASN A 321 -10.188 39.799 15.066 1.00127.22 O ATOM 2379 ND2 ASN A 321 -9.744 38.012 13.782 1.00128.58 N ATOM 2380 N LEU A 322 -5.695 41.834 13.469 1.00117.34 N ATOM 2381 CA LEU A 322 -4.292 42.246 13.504 1.00116.97 C ATOM 2382 C LEU A 322 -4.130 43.688 13.981 1.00113.15 C ATOM 2383 O LEU A 322 -3.205 43.991 14.736 1.00113.49 O ATOM 2384 CB LEU A 322 -3.620 42.054 12.139 1.00118.83 C ATOM 2385 CG LEU A 322 -2.986 40.686 11.858 1.00123.86 C ATOM 2386 CD1 LEU A 322 -4.013 39.654 11.388 1.00124.97 C ATOM 2387 CD2 LEU A 322 -1.872 40.829 10.833 1.00126.83 C ATOM 2388 N TYR A 323 -5.032 44.564 13.536 1.00106.53 N ATOM 2389 CA TYR A 323 -5.064 45.971 13.954 1.00 99.45 C ATOM 2390 C TYR A 323 -4.903 46.104 15.470 1.00 99.47 C ATOM 2391 O TYR A 323 -4.070 46.874 15.947 1.00102.32 O ATOM 2392 CB TYR A 323 -6.364 46.629 13.480 1.00 96.83 C ATOM 2393 CG TYR A 323 -6.587 48.050 13.952 1.00 95.64 C ATOM 2394 CD1 TYR A 323 -6.013 49.130 13.280 1.00 93.95 C ATOM 2395 CD2 TYR A 323 -7.398 48.316 15.057 1.00 98.88 C ATOM 2396 CE1 TYR A 323 -6.227 50.440 13.706 1.00 94.80 C ATOM 2397 CE2 TYR A 323 -7.614 49.623 15.496 1.00 98.65 C ATOM 2398 CZ TYR A 323 -7.026 50.679 14.815 1.00 98.22 C ATOM 2399 OH TYR A 323 -7.235 51.974 15.240 1.00 98.93 O ATOM 2400 N PHE A 324 -5.702 45.346 16.217 1.00 96.88 N ATOM 2401 CA PHE A 324 -5.537 45.242 17.658 1.00 91.30 C ATOM 2402 C PHE A 324 -4.450 44.202 17.937 1.00 90.79 C ATOM 2403 O PHE A 324 -4.446 43.539 18.972 1.00 94.43 O ATOM 2404 CB PHE A 324 -6.863 44.863 18.339 1.00 88.56 C ATOM 2405 CG PHE A 324 -7.997 45.826 18.061 1.00 87.40 C ATOM 2406 CD1 PHE A 324 -8.028 47.085 18.656 1.00 85.78 C ATOM 2407 CD2 PHE A 324 -9.043 45.463 17.215 1.00 87.41 C ATOM 2408 CE1 PHE A 324 -9.074 47.971 18.399 1.00 86.65 C ATOM 2409 CE2 PHE A 324 -10.095 46.340 16.954 1.00 85.28 C ATOM 2410 CZ PHE A 324 -10.111 47.595 17.550 1.00 87.25 C TER 2411 PHE A 324 HETATM 2412 O5' ADN A 400 -29.233 10.570 -26.022 1.00 69.66 O HETATM 2413 C5' ADN A 400 -29.464 11.813 -25.353 1.00 68.30 C HETATM 2414 C4' ADN A 400 -29.704 11.574 -23.867 1.00 67.77 C HETATM 2415 O4' ADN A 400 -30.665 10.527 -23.691 1.00 66.32 O HETATM 2416 C3' ADN A 400 -28.467 11.151 -23.084 1.00 67.30 C HETATM 2417 O3' ADN A 400 -27.725 12.245 -22.526 1.00 66.85 O HETATM 2418 C2' ADN A 400 -29.050 10.298 -21.985 1.00 67.53 C HETATM 2419 O2' ADN A 400 -29.376 11.115 -20.857 1.00 68.10 O HETATM 2420 C1' ADN A 400 -30.312 9.700 -22.584 1.00 68.07 C HETATM 2421 N9 ADN A 400 -30.022 8.307 -23.009 1.00 71.45 N HETATM 2422 C8 ADN A 400 -29.663 7.886 -24.242 1.00 72.29 C HETATM 2423 N7 ADN A 400 -29.463 6.542 -24.256 1.00 71.47 N HETATM 2424 C5 ADN A 400 -29.684 6.087 -23.011 1.00 70.56 C HETATM 2425 C6 ADN A 400 -29.657 4.773 -22.334 1.00 70.18 C HETATM 2426 N6 ADN A 400 -29.334 3.642 -23.008 1.00 69.90 N HETATM 2427 N1 ADN A 400 -29.968 4.745 -21.019 1.00 69.64 N HETATM 2428 C2 ADN A 400 -30.295 5.854 -20.327 1.00 70.55 C HETATM 2429 N3 ADN A 400 -30.341 7.079 -20.884 1.00 68.48 N HETATM 2430 C4 ADN A 400 -30.053 7.254 -22.194 1.00 70.16 C HETATM 2431 C1 SOG A 501 -37.529 -1.211 -38.282 1.00118.59 C HETATM 2432 C2 SOG A 501 -36.390 -1.664 -37.366 1.00116.70 C HETATM 2433 C3 SOG A 501 -36.505 -3.141 -36.987 1.00120.25 C HETATM 2434 C4 SOG A 501 -37.934 -3.612 -36.689 1.00124.55 C HETATM 2435 C5 SOG A 501 -38.985 -2.960 -37.593 1.00124.20 C HETATM 2436 C6 SOG A 501 -40.406 -3.241 -37.105 1.00123.51 C HETATM 2437 C1' SOG A 501 -39.014 1.108 -38.121 1.00106.52 C HETATM 2438 C2' SOG A 501 -39.101 2.628 -38.209 1.00100.04 C HETATM 2439 C3' SOG A 501 -40.415 3.131 -37.616 1.00 95.14 C HETATM 2440 C4' SOG A 501 -40.649 4.592 -37.981 1.00 92.84 C HETATM 2441 C5' SOG A 501 -41.904 5.129 -37.306 1.00 95.18 C HETATM 2442 C6' SOG A 501 -41.896 6.655 -37.280 1.00 95.04 C HETATM 2443 C7' SOG A 501 -43.099 7.200 -36.516 1.00 92.44 C HETATM 2444 C8' SOG A 501 -43.210 8.700 -36.684 1.00 90.78 C HETATM 2445 S1 SOG A 501 -37.424 0.528 -38.633 1.00115.86 S HETATM 2446 O2 SOG A 501 -35.144 -1.487 -38.038 1.00111.79 O HETATM 2447 O3 SOG A 501 -35.686 -3.381 -35.835 1.00121.37 O HETATM 2448 O4 SOG A 501 -37.985 -5.035 -36.861 1.00127.81 O HETATM 2449 O5 SOG A 501 -38.772 -1.546 -37.658 1.00122.98 O HETATM 2450 O6 SOG A 501 -40.792 -2.288 -36.107 1.00121.02 O HETATM 2451 C1 SOG A 502 -44.007 1.119 -32.816 1.00146.61 C HETATM 2452 C2 SOG A 502 -42.620 0.885 -32.216 1.00144.49 C HETATM 2453 C3 SOG A 502 -42.605 -0.270 -31.216 1.00143.90 C HETATM 2454 C4 SOG A 502 -43.814 -0.301 -30.275 1.00146.84 C HETATM 2455 C5 SOG A 502 -45.145 0.113 -30.925 1.00147.83 C HETATM 2456 C6 SOG A 502 -46.209 0.351 -29.844 1.00139.54 C HETATM 2457 C1' SOG A 502 -44.984 2.167 -35.162 1.00133.21 C HETATM 2458 C2' SOG A 502 -45.258 3.443 -35.948 1.00128.21 C HETATM 2459 C3' SOG A 502 -46.523 4.122 -35.439 1.00128.40 C HETATM 2460 C4' SOG A 502 -46.335 5.632 -35.353 1.00127.87 C HETATM 2461 C5' SOG A 502 -47.549 6.369 -35.912 1.00123.47 C HETATM 2462 C6' SOG A 502 -47.145 7.729 -36.470 1.00119.83 C HETATM 2463 C7' SOG A 502 -48.311 8.710 -36.456 1.00115.33 C HETATM 2464 C8' SOG A 502 -47.989 9.927 -37.294 1.00110.21 C HETATM 2465 S1 SOG A 502 -43.935 2.580 -33.812 1.00144.98 S HETATM 2466 O2 SOG A 502 -41.681 0.602 -33.262 1.00145.68 O HETATM 2467 O3 SOG A 502 -41.414 -0.171 -30.425 1.00142.55 O HETATM 2468 O4 SOG A 502 -43.930 -1.626 -29.742 1.00148.59 O HETATM 2469 O5 SOG A 502 -44.975 1.271 -31.763 1.00150.94 O HETATM 2470 O6 SOG A 502 -47.011 1.514 -30.098 1.00129.58 O HETATM 2471 O HOH A2001 -30.195 7.383 -16.934 1.00 67.61 O HETATM 2472 O HOH A2002 -32.134 5.400 -17.160 1.00 78.45 O HETATM 2473 O HOH A2003 -23.818 23.832 -27.048 1.00 74.18 O HETATM 2474 O HOH A2004 -19.668 31.567 -33.807 1.00 92.41 O HETATM 2475 O HOH A2005 -48.908 -1.908 -16.272 1.00 73.49 O HETATM 2476 O HOH A2006 -41.706 -1.563 -15.739 1.00 82.62 O HETATM 2477 O HOH A2007 -33.150 2.923 -18.549 1.00 54.94 O HETATM 2478 O HOH A2008 -12.327 30.488 -30.645 1.00 84.62 O HETATM 2479 O HOH A2009 -20.844 8.596 -23.721 1.00 90.78 O HETATM 2480 O HOH A2010 -27.715 5.617 -29.587 1.00 59.27 O HETATM 2481 O HOH A2011 -27.264 0.570 -24.417 1.00 74.89 O HETATM 2482 O HOH A2012 -24.645 17.286 -23.628 1.00 71.50 O HETATM 2483 O HOH A2013 -12.948 30.708 -33.641 1.00 85.45 O HETATM 2484 O HOH A2014 -10.214 46.977 -12.681 1.00 94.90 O HETATM 2485 O HOH A2015 -8.838 53.519 16.913 1.00 48.91 O HETATM 2486 O HOH A2016 -30.468 9.443 -18.982 1.00 56.86 O HETATM 2487 O HOH A2017 -28.156 11.520 -28.345 1.00 67.66 O HETATM 2488 O HOH A2018 -30.373 2.608 -19.382 1.00 58.03 O CONECT 485 1141 CONECT 501 1050 CONECT 521 1185 CONECT 1050 501 CONECT 1141 485 CONECT 1185 521 CONECT 1862 1883 CONECT 1883 1862 CONECT 2412 2413 CONECT 2413 2412 2414 CONECT 2414 2413 2415 2416 CONECT 2415 2414 2420 CONECT 2416 2414 2417 2418 CONECT 2417 2416 CONECT 2418 2416 2419 2420 CONECT 2419 2418 CONECT 2420 2415 2418 2421 CONECT 2421 2420 2422 2430 CONECT 2422 2421 2423 CONECT 2423 2422 2424 CONECT 2424 2423 2425 2430 CONECT 2425 2424 2426 2427 CONECT 2426 2425 CONECT 2427 2425 2428 CONECT 2428 2427 2429 CONECT 2429 2428 2430 CONECT 2430 2421 2424 2429 CONECT 2431 2432 2445 2449 CONECT 2432 2431 2433 2446 CONECT 2433 2432 2434 2447 CONECT 2434 2433 2435 2448 CONECT 2435 2434 2436 2449 CONECT 2436 2435 2450 CONECT 2437 2438 2445 CONECT 2438 2437 2439 CONECT 2439 2438 2440 CONECT 2440 2439 2441 CONECT 2441 2440 2442 CONECT 2442 2441 2443 CONECT 2443 2442 2444 CONECT 2444 2443 CONECT 2445 2431 2437 CONECT 2446 2432 CONECT 2447 2433 CONECT 2448 2434 CONECT 2449 2431 2435 CONECT 2450 2436 CONECT 2451 2452 2465 2469 CONECT 2452 2451 2453 2466 CONECT 2453 2452 2454 2467 CONECT 2454 2453 2455 2468 CONECT 2455 2454 2456 2469 CONECT 2456 2455 2470 CONECT 2457 2458 2465 CONECT 2458 2457 2459 CONECT 2459 2458 2460 CONECT 2460 2459 2461 CONECT 2461 2460 2462 CONECT 2462 2461 2463 CONECT 2463 2462 2464 CONECT 2464 2463 CONECT 2465 2451 2457 CONECT 2466 2452 CONECT 2467 2453 CONECT 2468 2454 CONECT 2469 2451 2455 CONECT 2470 2456 MASTER 310 0 3 20 2 0 0 6 2487 1 67 25 END