CHEMBL3642785


SMILES Cc1cnc(N2CCN(CC[C@H]3CC[C@H](NC(=O)C4CCOCC4)CC3)CC2)c2c1OCC2
InChIKey KMPUTTSRRTYIRY-AQYVVDRMSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 456.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.01 7.01 7.01 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.35 5.35 5.35 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.71 7.71 7.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database