Ligand bias for G protein subtype

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Receptor Tested Ligand Pair Receptor transducers Pathway Bias Rank Order Operational model
ΔΔ(Tau/Ka)
Intrinsic relative
activity
(ΔΔLog(Emax/EC50))
Potency ratio Potency (EC50 or
IC50)
Emax (% of ref ligand) Transduction coefficient Assay Cell line Time resolved Reference
Class
Family UniProt IUPHAR Species Endogenous
Ligand
Reference Biased #Ven
dors
#Arti
cles
#Labs
Primary Secondary P 1 P 2 P 3 P 4 P 5 P 2 P 3 P 4 P 5 P 2 P 3 P 4 P 5 P 2 P 3 P 4 P 5 P 1 P 2 P 3 P 4 P 5 P 1 P 2 P 3 P 4 P 5 P 1 P 2 P 3 P 4 P 5 P 1 P 2 P 3 P 4 P 5 P 1 P 2 P 3 P 4 P 5 P 1 P 2 P 3 P 4 P 5 Authors DOI/
Reference