Ligand source activities (1 row/activity)



Get vendors


Ligands (move mouse cursor over ligand name to see structure) Receptor Activity Chemical information
Sel. page Common
name		 GPCRdb
ID		 Reference
ligand		 Vendors

 Species

 Assay
Type

 Activity
Type		 Activity
Relation		 Activity
Value		 p-value
(-log)		 Fold
selectivity		 Tested
GPCRs		 Assay
Description		 Source

 Mol
weight		 Rot
Bonds		 H don

 H acc

 LogP

 Smiles

 DOI
4157793 47286 None 6 Human Functional pIC50 = 5 5.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 417 5 2 8 2.7 COc1ccc(C2=NN(c3nc(C(=O)O)cs3)C(O)(C(F)(F)F)C2)c(OC)c1 nan
CHEMBL1543980 47286 None 6 Human Functional pIC50 = 5 5.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 417 5 2 8 2.7 COc1ccc(C2=NN(c3nc(C(=O)O)cs3)C(O)(C(F)(F)F)C2)c(OC)c1 nan
2368939 55515 None 6 Human Functional pIC50 = 5 5.0 1 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 2 0 2 6.0 CC(C)(C)c1ccc(-c2c[n+](-c3ccc(Br)cc3)c3n2CCCS3)cc1 nan
CHEMBL1416660 55515 None 6 Human Functional pIC50 = 5 5.0 1 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 2 0 2 6.0 CC(C)(C)c1ccc(-c2c[n+](-c3ccc(Br)cc3)c3n2CCCS3)cc1 nan
CHEMBL1620142 55515 None 6 Human Functional pIC50 = 5 5.0 1 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 2 0 2 6.0 CC(C)(C)c1ccc(-c2c[n+](-c3ccc(Br)cc3)c3n2CCCS3)cc1 nan
842058 28684 None 19 Human Functional pIC50 = 6 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 343 4 0 4 3.0 Cc1nn(C)c(C)c1CN(C)S(=O)(=O)c1ccc2ccccc2c1 nan
CHEMBL1377607 28684 None 19 Human Functional pIC50 = 6 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 343 4 0 4 3.0 Cc1nn(C)c(C)c1CN(C)S(=O)(=O)c1ccc2ccccc2c1 nan
3006170 59567 None 5 Human Functional pIC50 = 6 6.0 -2 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 325 3 5 9 -1.7 NC(=S)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12 nan
CHEMBL171699 59567 None 5 Human Functional pIC50 = 6 6.0 -2 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 325 3 5 9 -1.7 NC(=S)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12 nan
2323706 39147 None 3 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 314 8 1 4 3.5 CC(C)CCOc1cccc(OCC(=O)Nc2ccncc2)c1 nan
CHEMBL1469379 39147 None 3 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 314 8 1 4 3.5 CC(C)CCOc1cccc(OCC(=O)Nc2ccncc2)c1 nan
53385430 88798 None 0 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 5 0 4 4.2 Fc1ccc(CN2CCN(c3ncc(Cc4ccccc4)cn3)CC2)c(Cl)c1 nan
CHEMBL2362703 88798 None 0 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 5 0 4 4.2 Fc1ccc(CN2CCN(c3ncc(Cc4ccccc4)cn3)CC2)c(Cl)c1 nan
4544702 47535 None 1 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 448 6 1 5 5.9 O=C(Nc1nc(-c2ccc(Cl)cc2Cl)cs1)c1ccc(OCC2CCCO2)cc1 nan
CHEMBL1545848 47535 None 1 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 448 6 1 5 5.9 O=C(Nc1nc(-c2ccc(Cl)cc2Cl)cs1)c1ccc(OCC2CCCO2)cc1 nan
3932658 59425 None 4 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 5 1 7 1.3 NC(=O)c1ccc(N2CCN(S(=O)(=O)c3cccs3)CC2)c([N+](=O)[O-])c1 nan
CHEMBL1709973 59425 None 4 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 5 1 7 1.3 NC(=O)c1ccc(N2CCN(S(=O)(=O)c3cccs3)CC2)c([N+](=O)[O-])c1 nan
44825951 67595 None 0 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 376 13 1 4 4.6 CCCCC[C@@H](/C=C/C1C(=O)C=C[C@H]1C/C=C\CCCC(=O)O)OC(C)=O nan
CHEMBL1899895 67595 None 0 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 376 13 1 4 4.6 CCCCC[C@@H](/C=C/C1C(=O)C=C[C@H]1C/C=C\CCCC(=O)O)OC(C)=O nan
729558 200154 None 6 Human Functional pIC50 = 6.0 6.0 1 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 233 3 0 6 1.1 CCOc1nc(C#N)nc(N2CCCCC2)n1 nan
CHEMBL571295 200154 None 6 Human Functional pIC50 = 6.0 6.0 1 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 233 3 0 6 1.1 CCOc1nc(C#N)nc(N2CCCCC2)n1 nan
10662 127585 None 20 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 398 3 2 4 3.7 O=C(C(=O)c1cc(Br)ccc1O)c1cc(Br)ccc1O nan
CHEMBL366205 127585 None 20 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 398 3 2 4 3.7 O=C(C(=O)c1cc(Br)ccc1O)c1cc(Br)ccc1O nan
1155337 42216 None 2 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 490 8 0 8 4.8 O=C(CSc1nnc(Cn2nnc3ccccc32)o1)N(Cc1ccc(Cl)cc1)c1ccccc1 nan
CHEMBL1497024 42216 None 2 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 490 8 0 8 4.8 O=C(CSc1nnc(Cn2nnc3ccccc32)o1)N(Cc1ccc(Cl)cc1)c1ccccc1 nan
648690 31513 None 3 Human Functional pIC50 = 6.0 6.0 1 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 354 4 1 4 2.8 Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccc(N2CCCC2=O)cc1 nan
CHEMBL1403484 31513 None 3 Human Functional pIC50 = 6.0 6.0 1 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 354 4 1 4 2.8 Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccc(N2CCCC2=O)cc1 nan
24791438 60018 None 5 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 399 6 0 5 3.8 CSc1ccc(C(=O)C2CCCN(C(=O)CCc3c(C)nn(C)c3C)C2)cc1 nan
CHEMBL1734666 60018 None 5 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 399 6 0 5 3.8 CSc1ccc(C(=O)C2CCCN(C(=O)CCc3c(C)nn(C)c3C)C2)cc1 nan
1952659 40468 None 8 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 379 5 1 7 3.9 O=C(CSc1nnc(-c2cccnc2)s1)Nc1ccnc2ccccc12 nan
CHEMBL1482468 40468 None 8 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 379 5 1 7 3.9 O=C(CSc1nnc(-c2cccnc2)s1)Nc1ccnc2ccccc12 nan
16235315 28126 None 3 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 6 1 4 3.5 CC(CC(=O)Nc1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1)c1ccccc1 nan
CHEMBL1373162 28126 None 3 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 6 1 4 3.5 CC(CC(=O)Nc1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1)c1ccccc1 nan
992688 34988 None 9 Human Functional pIC50 = 5.9 5.9 10 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 372 7 0 8 3.3 COc1cc(CSc2nnnn2-c2ccc(C)cc2)cc(OC)c1OC nan
CHEMBL1432721 34988 None 9 Human Functional pIC50 = 5.9 5.9 10 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 372 7 0 8 3.3 COc1cc(CSc2nnnn2-c2ccc(C)cc2)cc(OC)c1OC nan
6906133 108339 None 2 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 404 9 1 5 4.0 COc1ccc(/C=N/OCC(=O)NC(c2ccccc2)c2ccccc2)cc1OC nan
CHEMBL3197447 108339 None 2 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 404 9 1 5 4.0 COc1ccc(/C=N/OCC(=O)NC(c2ccccc2)c2ccccc2)cc1OC nan
4969272 36632 None 3 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.4 CC(=O)c1ccc(N2CCN(C(S)=Nc3ccc(Oc4ccccc4)cc3)CC2)cc1 nan
CHEMBL1448690 36632 None 3 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.4 CC(=O)c1ccc(N2CCN(C(S)=Nc3ccc(Oc4ccccc4)cc3)CC2)cc1 nan
647700 47692 None 6 Human Functional pIC50 = 5.9 5.9 12 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 474 8 0 8 4.3 O=C(CSc1nnc(Cn2nnc3ccccc32)o1)N(Cc1ccc(F)cc1)c1ccccc1 nan
CHEMBL1547232 47692 None 6 Human Functional pIC50 = 5.9 5.9 12 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 474 8 0 8 4.3 O=C(CSc1nnc(Cn2nnc3ccccc32)o1)N(Cc1ccc(F)cc1)c1ccccc1 nan
2405889 48843 None 2 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 327 6 1 3 4.5 CC(=O)c1c(C)[nH]c(C(=O)COc2cc(C)ccc2C(C)C)c1C nan
CHEMBL1559053 48843 None 2 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 327 6 1 3 4.5 CC(=O)c1c(C)[nH]c(C(=O)COc2cc(C)ccc2C(C)C)c1C nan
135521496 88727 None 3 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 523 6 3 13 1.8 Nc1nonc1-n1nnc(C(=O)N/N=C/c2cc(Br)ccc2O)c1CSC1=NCCS1 nan
CHEMBL2359911 88727 None 3 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 523 6 3 13 1.8 Nc1nonc1-n1nnc(C(=O)N/N=C/c2cc(Br)ccc2O)c1CSC1=NCCS1 nan
24790899 53450 None 1 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 367 8 0 5 4.1 C=CCC1(CC=C)CCCN1C(=O)c1cc(COc2ccc(C)nc2)on1 nan
CHEMBL1600776 53450 None 1 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 367 8 0 5 4.1 C=CCC1(CC=C)CCCN1C(=O)c1cc(COc2ccc(C)nc2)on1 nan
616573 4600 None 20 Human Functional pIC50 = 5.9 5.9 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
CHEMBL102726 4600 None 20 Human Functional pIC50 = 5.9 5.9 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
CHEMBL1444764 4600 None 20 Human Functional pIC50 = 5.9 5.9 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
49778835 67235 None 0 Human Functional pIC50 = 6.9 6.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 388 6 1 5 4.4 COc1ccc(CNC(=O)c2cccc3c(-c4cccnc4)coc23)cc1OC nan
CHEMBL1878609 67235 None 0 Human Functional pIC50 = 6.9 6.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 388 6 1 5 4.4 COc1ccc(CNC(=O)c2cccc3c(-c4cccnc4)coc23)cc1OC nan
984148 47013 None 2 Human Functional pIC50 = 4.9 4.9 -1 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 6 3 6 3.9 CCCc1cc(-c2[nH]ncc2-c2ccc(C(=O)OCC)o2)c(O)cc1O nan
CHEMBL1541596 47013 None 2 Human Functional pIC50 = 4.9 4.9 -1 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 6 3 6 3.9 CCCc1cc(-c2[nH]ncc2-c2ccc(C(=O)OCC)o2)c(O)cc1O nan
16196350 55065 None 0 Human Functional pIC50 = 6.9 6.9 48 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccccc1N1C(C)=CC(=Cc2sc3ccccc3[n+]2C)C=C1C nan
3253322 55065 None 0 Human Functional pIC50 = 6.9 6.9 48 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccccc1N1C(C)=CC(=Cc2sc3ccccc3[n+]2C)C=C1C nan
5773522 55065 None 0 Human Functional pIC50 = 6.9 6.9 48 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccccc1N1C(C)=CC(=Cc2sc3ccccc3[n+]2C)C=C1C nan
CHEMBL1323872 55065 None 0 Human Functional pIC50 = 6.9 6.9 48 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccccc1N1C(C)=CC(=Cc2sc3ccccc3[n+]2C)C=C1C nan
CHEMBL1616531 55065 None 0 Human Functional pIC50 = 6.9 6.9 48 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccccc1N1C(C)=CC(=Cc2sc3ccccc3[n+]2C)C=C1C nan
3146673 48032 None 12 Human Functional pIC50 = 6.9 6.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 249 3 1 3 3.8 CC(Nc1ncnc2ccccc12)c1ccccc1 nan
CHEMBL1550278 48032 None 12 Human Functional pIC50 = 6.9 6.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 249 3 1 3 3.8 CC(Nc1ncnc2ccccc12)c1ccccc1 nan
5153 112015 None 12 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
CHEMBL1584044 112015 None 12 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
CHEMBL328834 112015 None 12 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
1878823 199638 None 6 Human Functional pIC50 = 5.9 5.9 4 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 11 1 2 4.9 CCCCCCCCCCCCn1ccc(=N)cc1 nan
CHEMBL1544561 199638 None 6 Human Functional pIC50 = 5.9 5.9 4 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 11 1 2 4.9 CCCCCCCCCCCCn1ccc(=N)cc1 nan
CHEMBL568092 199638 None 6 Human Functional pIC50 = 5.9 5.9 4 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 11 1 2 4.9 CCCCCCCCCCCCn1ccc(=N)cc1 nan
20968904 51578 None 5 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 469 8 1 5 5.3 Cc1oc(-c2ccc(Cl)cc2)nc1CSCC(=O)NC1CCN(Cc2ccccc2)CC1 nan
CHEMBL1583186 51578 None 5 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 469 8 1 5 5.3 Cc1oc(-c2ccc(Cl)cc2)nc1CSCC(=O)NC1CCN(Cc2ccccc2)CC1 nan
976991 34154 None 6 Human Functional pIC50 = 4.9 4.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 331 3 1 5 2.7 NC(=O)c1cn(-c2ccccc2)nc1-c1cc2ccccc2oc1=O nan
CHEMBL1425860 34154 None 6 Human Functional pIC50 = 4.9 4.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 331 3 1 5 2.7 NC(=O)c1cn(-c2ccccc2)nc1-c1cc2ccccc2oc1=O nan
24817489 24820 None 1 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 381 6 0 6 3.3 COCC1CCCN(C(=O)c2cc(COc3ccc4ncccc4c3)on2)C1 nan
CHEMBL1344808 24820 None 1 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 381 6 0 6 3.3 COCC1CCCN(C(=O)c2cc(COc3ccc4ncccc4c3)on2)C1 nan
787494 38075 None 6 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 276 3 1 2 3.7 Cc1cc(NC(=O)Cc2ccccc2)c2ccccc2n1 nan
CHEMBL1460627 38075 None 6 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 276 3 1 2 3.7 Cc1cc(NC(=O)Cc2ccccc2)c2ccccc2n1 nan
51360001 88759 None 0 Human Functional pIC50 = 4.9 4.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 392 3 0 3 6.4 FC(F)(F)c1ccccc1Cc1c(-c2ccco2)nc2c3ccccc3ccn12 nan
CHEMBL2361231 88759 None 0 Human Functional pIC50 = 4.9 4.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 392 3 0 3 6.4 FC(F)(F)c1ccccc1Cc1c(-c2ccco2)nc2c3ccccc3ccn12 nan
5153 112015 None 12 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
CHEMBL1584044 112015 None 12 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
CHEMBL328834 112015 None 12 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 309 3 5 9 -2.3 NC(=O)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 nan
650985 42493 None 1 Human Functional pIC50 = 5.9 5.9 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 5 1 6 2.4 COc1ccc(CCNc2c(C)c(C)nc3ncnn23)cc1 nan
CHEMBL1499501 42493 None 1 Human Functional pIC50 = 5.9 5.9 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 5 1 6 2.4 COc1ccc(CCNc2c(C)c(C)nc3ncnn23)cc1 nan
404407 60241 None 0 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 2 0 2 3.4 CN(C)c1ccc(C=c2c3ccccc3n3c2c2c([n+]3C)CCCC2)cc1 nan
5472654 60241 None 0 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 2 0 2 3.4 CN(C)c1ccc(C=c2c3ccccc3n3c2c2c([n+]3C)CCCC2)cc1 nan
CHEMBL1721330 60241 None 0 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 2 0 2 3.4 CN(C)c1ccc(C=c2c3ccccc3n3c2c2c([n+]3C)CCCC2)cc1 nan
CHEMBL1740248 60241 None 0 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 356 2 0 2 3.4 CN(C)c1ccc(C=c2c3ccccc3n3c2c2c([n+]3C)CCCC2)cc1 nan
2766344 32635 None 13 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 496 10 0 8 3.6 COC(=O)C1CCN(Cc2ccc(OCCCN3CCN(c4ccc([N+](=O)[O-])cc4)CC3)cc2)CC1 nan
CHEMBL1412887 32635 None 13 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 496 10 0 8 3.6 COC(=O)C1CCN(Cc2ccc(OCCCN3CCN(c4ccc([N+](=O)[O-])cc4)CC3)cc2)CC1 nan
3306 208719 None 28 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 181 4 3 3 1.0 CCNCC(O)c1cccc(O)c1 nan
CHEMBL86882 208719 None 28 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 181 4 3 3 1.0 CCNCC(O)c1cccc(O)c1 nan
2800172 37074 None 4 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 4 1 4 4.8 CC(C)(C)c1ccc(C(=O)Nc2ccc(Oc3cccnc3)nc2)cc1 nan
CHEMBL1452130 37074 None 4 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 4 1 4 4.8 CC(C)(C)c1ccc(C(=O)Nc2ccc(Oc3cccnc3)nc2)cc1 nan
9261962 26233 None 2 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 400 7 0 7 2.6 CC(C)c1ccc(CN2CCN(C(=O)CSc3nnnn3C3CC3)CC2)cc1 nan
CHEMBL1357535 26233 None 2 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 400 7 0 7 2.6 CC(C)c1ccc(CN2CCN(C(=O)CSc3nnnn3C3CC3)CC2)cc1 nan
49786188 67154 None 0 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 370 8 2 6 3.7 O=C(Nc1ccc(Oc2ccccc2)cc1)c1csc(COCCO)n1 nan
CHEMBL1875054 67154 None 0 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 370 8 2 6 3.7 O=C(Nc1ccc(Oc2ccccc2)cc1)c1csc(COCCO)n1 nan
646459 36924 None 1 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 371 5 1 5 3.9 O=C(CN1CCC(c2nc3ccccc3s2)CC1)NCc1cccs1 nan
CHEMBL1451015 36924 None 1 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 371 5 1 5 3.9 O=C(CN1CCC(c2nc3ccccc3s2)CC1)NCc1cccs1 nan
743662 59782 None 7 Human Functional pIC50 = 6.9 6.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 300 2 0 2 4.2 Cc1nc2ccccc2n1Cc1ccc(Br)cc1 nan
CHEMBL1725453 59782 None 7 Human Functional pIC50 = 6.9 6.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 300 2 0 2 4.2 Cc1nc2ccccc2n1Cc1ccc(Br)cc1 nan
1254286 33158 None 4 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 334 4 1 3 3.5 Cc1cc(OCC(=O)Nc2ccncc2)c(C)cc1Br nan
CHEMBL1417355 33158 None 4 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 334 4 1 3 3.5 Cc1cc(OCC(=O)Nc2ccncc2)c(C)cc1Br nan
2374706 51433 None 3 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 501 7 2 6 5.2 COc1ccc(-c2csc(NC(=O)c3ccccc3NS(=O)(=O)c3ccc(F)c(F)c3)n2)cc1 nan
CHEMBL1581949 51433 None 3 Human Functional pIC50 = 5.9 5.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 501 7 2 6 5.2 COc1ccc(-c2csc(NC(=O)c3ccccc3NS(=O)(=O)c3ccc(F)c(F)c3)n2)cc1 nan
2795668 29693 None 2 Human Functional pIC50 = 6.9 6.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 416 2 1 3 4.5 Fc1ccc(N=C(S)N2CCCN(c3ccc(C(F)(F)F)cn3)CC2)c(F)c1 nan
CHEMBL1386344 29693 None 2 Human Functional pIC50 = 6.9 6.9 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 416 2 1 3 4.5 Fc1ccc(N=C(S)N2CCCN(c3ccc(C(F)(F)F)cn3)CC2)c(F)c1 nan
655948 26631 None 5 Human Functional pIC50 = 5.9 5.9 17 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 351 2 0 8 2.4 Cc1cc(N2CCN(c3nc4ccccc4s3)CC2)n2ncnc2n1 nan
CHEMBL1361461 26631 None 5 Human Functional pIC50 = 5.9 5.9 17 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 351 2 0 8 2.4 Cc1cc(N2CCN(c3nc4ccccc4s3)CC2)n2ncnc2n1 nan
24793159 38183 None 1 Human Functional pIC50 = 6.8 6.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 377 3 1 5 3.7 Cn1nccc1C(=O)NC1CCCc2c1cnn2-c1ccc(C(C)(C)C)cc1 nan
CHEMBL1461631 38183 None 1 Human Functional pIC50 = 6.8 6.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 377 3 1 5 3.7 Cn1nccc1C(=O)NC1CCCc2c1cnn2-c1ccc(C(C)(C)C)cc1 nan
657154 52131 None 10 Human Functional pIC50 = 5.8 5.8 6 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 467 6 2 5 5.3 Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)Nc2nc(-c3ccc(F)cc3)cs2)cc1 nan
CHEMBL1587630 52131 None 10 Human Functional pIC50 = 5.8 5.8 6 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 467 6 2 5 5.3 Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)Nc2nc(-c3ccc(F)cc3)cs2)cc1 nan
51360013 88726 None 0 Human Functional pIC50 = 4.8 4.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 434 3 0 3 6.3 Cc1cc(Br)cn2c(Cc3ccccc3C(F)(F)F)c(-c3ccco3)nc12 nan
CHEMBL2359888 88726 None 0 Human Functional pIC50 = 4.8 4.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 434 3 0 3 6.3 Cc1cc(Br)cn2c(Cc3ccccc3C(F)(F)F)c(-c3ccco3)nc12 nan
1966784 20746 None 5 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 414 6 2 6 3.9 CCOC(=O)c1[nH]c2ccc(OC)cc2c1NS(=O)(=O)c1ccc(Cl)s1 nan
CHEMBL1309273 20746 None 5 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 414 6 2 6 3.9 CCOC(=O)c1[nH]c2ccc(OC)cc2c1NS(=O)(=O)c1ccc(Cl)s1 nan
9551471 21802 None 9 Human Functional pIC50 = 6.8 6.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 478 7 1 7 2.6 CCCCCn1c(=O)[nH]c2cc(C(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)ccc2c1=O nan
CHEMBL1319304 21802 None 9 Human Functional pIC50 = 6.8 6.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 478 7 1 7 2.6 CCCCCn1c(=O)[nH]c2cc(C(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)ccc2c1=O nan
24819530 47321 None 0 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 395 5 0 7 3.0 COC(=O)C1CCCCN1C(=O)c1cc(COc2cccc3cnccc23)on1 nan
CHEMBL1544190 47321 None 0 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 395 5 0 7 3.0 COC(=O)C1CCCCN1C(=O)c1cc(COc2cccc3cnccc23)on1 nan
243725 97171 None 30 Human Functional pIC50 = 7.8 7.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 3 0 6 3.8 COc1cc2c(cc1OC)[C@@H]1C(=O)c3ccc4c(c3O[C@@H]1CO2)C[C@H](C(C)C)O4 nan
CHEMBL267630 97171 None 30 Human Functional pIC50 = 7.8 7.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 3 0 6 3.8 COc1cc2c(cc1OC)[C@@H]1C(=O)c3ccc4c(c3O[C@@H]1CO2)C[C@H](C(C)C)O4 nan
2795769 26936 None 2 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 3 1 5 4.9 Cc1c(Cl)cccc1NC(=O)N1CCCN(c2nc(-c3ccccc3)ns2)CC1 nan
CHEMBL1364108 26936 None 2 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 3 1 5 4.9 Cc1c(Cl)cccc1NC(=O)N1CCCN(c2nc(-c3ccccc3)ns2)CC1 nan
2356907 42478 None 3 Human Functional pIC50 = 6.8 6.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 343 2 1 3 4.0 Cc1nn(C)c(Nc2ccc(Br)cc2)c1Br nan
CHEMBL1499354 42478 None 3 Human Functional pIC50 = 6.8 6.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 343 2 1 3 4.0 Cc1nn(C)c(Nc2ccc(Br)cc2)c1Br nan
2537601 44151 None 3 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 10 2 8 2.0 COc1cc(CCC(=O)OCC(=O)Nc2sccc2C(N)=O)cc(OC)c1OC nan
CHEMBL1515567 44151 None 3 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 10 2 8 2.0 COc1cc(CCC(=O)OCC(=O)Nc2sccc2C(N)=O)cc(OC)c1OC nan
3155818 43713 None 5 Human Functional pIC50 = 5.8 5.8 5 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 368 8 1 6 3.4 CCCOC(=O)c1ccc(OCC(O)Cn2c(C)nc3ccccc32)cc1 nan
CHEMBL1510261 43713 None 5 Human Functional pIC50 = 5.8 5.8 5 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 368 8 1 6 3.4 CCCOC(=O)c1ccc(OCC(O)Cn2c(C)nc3ccccc32)cc1 nan
1231799 24270 None 9 Human Functional pIC50 = 6.8 6.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 3 1 3 3.0 Cc1nn(C)c(C(=O)NCc2ccc(Cl)cc2)c1Cl nan
CHEMBL1340112 24270 None 9 Human Functional pIC50 = 6.8 6.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 3 1 3 3.0 Cc1nn(C)c(C(=O)NCc2ccc(Cl)cc2)c1Cl nan
2318546 59316 None 5 Human Functional pIC50 = 6.8 6.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 334 6 1 4 4.2 Cc1ccc(Oc2ccc(OCC(=O)Nc3ccncc3)cc2)cc1 nan
CHEMBL1705098 59316 None 5 Human Functional pIC50 = 6.8 6.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 334 6 1 4 4.2 Cc1ccc(Oc2ccc(OCC(=O)Nc3ccncc3)cc2)cc1 nan
187 255 None 24 Human Functional pIC50 = 5.8 5.8 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
187.0 255 None 24 Human Functional pIC50 = 5.8 5.8 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
294 255 None 24 Human Functional pIC50 = 5.8 5.8 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
65 255 None 24 Human Functional pIC50 = 5.8 5.8 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
8593 255 None 24 Human Functional pIC50 = 5.8 5.8 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
CHEMBL667 255 None 24 Human Functional pIC50 = 5.8 5.8 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
DB03128 255 None 24 Human Functional pIC50 = 5.8 5.8 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
2349797 27572 None 5 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 307 4 2 2 3.8 S=C(NCCc1ccccc1)Nc1cccc2cnccc12 nan
CHEMBL1369262 27572 None 5 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 307 4 2 2 3.8 S=C(NCCc1ccccc1)Nc1cccc2cnccc12 nan
5613808 39306 None 5 Human Functional pIC50 = 4.8 4.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 214 1 2 5 1.2 O=[N+]([O-])c1[nH]c2nc(O)nc-2cc1Cl nan
CHEMBL1470764 39306 None 5 Human Functional pIC50 = 4.8 4.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 214 1 2 5 1.2 O=[N+]([O-])c1[nH]c2nc(O)nc-2cc1Cl nan
51360490 67119 None 0 Human Functional pIC50 = 7.8 7.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 1059 8 1 13 5.2 CC[C@H](C)C1C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H](COC)C(=O)N2CCC[C@H]2C(=O)N(C)[C@@H](C(C)C)C(=O)N2CCC[C@H]2C(=O)O[C@H](CC)CCC[C@@H](O)[C@@H](C)C(=O)O[C@H](C)[C@@H](C)C/C=C(C)/C(OC)=C\C(=O)N1C nan
CHEMBL1873644 67119 None 0 Human Functional pIC50 = 7.8 7.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 1059 8 1 13 5.2 CC[C@H](C)C1C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H](COC)C(=O)N2CCC[C@H]2C(=O)N(C)[C@@H](C(C)C)C(=O)N2CCC[C@H]2C(=O)O[C@H](CC)CCC[C@@H](O)[C@@H](C)C(=O)O[C@H](C)[C@@H](C)C/C=C(C)/C(OC)=C\C(=O)N1C nan
2874826 29732 None 10 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 276 3 1 5 1.5 CC1CC(=O)NN=C1c1ccc(N(C)C)c([N+](=O)[O-])c1 nan
CHEMBL1386646 29732 None 10 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 276 3 1 5 1.5 CC1CC(=O)NN=C1c1ccc(N(C)C)c([N+](=O)[O-])c1 nan
823638 53794 None 13 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 278 4 1 3 3.3 O=C(COc1ccc2ccccc2c1)Nc1ccncc1 nan
CHEMBL1603921 53794 None 13 Human Functional pIC50 = 5.8 5.8 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 278 4 1 3 3.3 O=C(COc1ccc2ccccc2c1)Nc1ccncc1 nan
2426360 46901 None 3 Human Functional pIC50 = 5.8 5.8 8 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 382 3 3 3 4.6 Fc1ccc(N=C(S)NNc2ncc(C(F)(F)F)cc2Cl)c(F)c1 nan
CHEMBL1540808 46901 None 3 Human Functional pIC50 = 5.8 5.8 8 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 382 3 3 3 4.6 Fc1ccc(N=C(S)NNc2ncc(C(F)(F)F)cc2Cl)c(F)c1 nan
714273 22859 None 7 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 244 2 0 6 0.9 N#Cc1nc(N2CCCC2)nc(N2CCCC2)n1 nan
CHEMBL1328481 22859 None 7 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 244 2 0 6 0.9 N#Cc1nc(N2CCCC2)nc(N2CCCC2)n1 nan
2811299 44834 None 2 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 315 3 1 5 2.4 Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1522108 44834 None 2 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 315 3 1 5 2.4 Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccc2c(c1)OCO2 nan
1126136 55861 None 9 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 371 5 0 5 3.3 CSc1ccc(CN2CCN(C(=O)c3ccc([N+](=O)[O-])cc3)CC2)cc1 nan
CHEMBL1522672 55861 None 9 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 371 5 0 5 3.3 CSc1ccc(CN2CCN(C(=O)c3ccc([N+](=O)[O-])cc3)CC2)cc1 nan
CHEMBL1623172 55861 None 9 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 371 5 0 5 3.3 CSc1ccc(CN2CCN(C(=O)c3ccc([N+](=O)[O-])cc3)CC2)cc1 nan
660194 32208 None 12 Human Functional pIC50 = 5.7 5.7 6 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 319 8 1 7 1.6 C=CCNc1nc2c(c(=O)n(C)c(=O)n2C)n1CCCCCC nan
CHEMBL1409445 32208 None 12 Human Functional pIC50 = 5.7 5.7 6 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 319 8 1 7 1.6 C=CCNc1nc2c(c(=O)n(C)c(=O)n2C)n1CCCCCC nan
1599306 14160 None 5 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 220 8 1 2 3.7 CCCCCCCCCn1ccc(=N)cc1 nan
CHEMBL1198353 14160 None 5 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 220 8 1 2 3.7 CCCCCCCCCn1ccc(=N)cc1 nan
CHEMBL601933 14160 None 5 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 220 8 1 2 3.7 CCCCCCCCCn1ccc(=N)cc1 nan
646580 30385 None 2 Human Functional pIC50 = 5.7 5.7 6 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 382 5 3 7 1.9 CC(C)(C)NC(=O)COC(=O)c1snc(C(=O)NC2CCCCC2)c1N nan
CHEMBL1392033 30385 None 2 Human Functional pIC50 = 5.7 5.7 6 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 382 5 3 7 1.9 CC(C)(C)NC(=O)COC(=O)c1snc(C(=O)NC2CCCCC2)c1N nan
3237192 47513 None 1 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.2 Cc1oc(-c2ccc(Cl)cc2)nc1CN1CCCC(C(=O)NCc2cccnc2)C1 nan
CHEMBL1545631 47513 None 1 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.2 Cc1oc(-c2ccc(Cl)cc2)nc1CN1CCCC(C(=O)NCc2cccnc2)C1 nan
69765 85162 None 54 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 251 1 1 3 3.9 CC(C)(C)c1cc([N+](=O)[O-])cc(C(C)(C)C)c1O nan
CHEMBL224869 85162 None 54 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 251 1 1 3 3.9 CC(C)(C)c1cc([N+](=O)[O-])cc(C(C)(C)C)c1O nan
20968908 19622 None 5 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 528 11 1 6 3.9 Cc1oc(-c2ccc(Cl)cc2)nc1C[S+]([O-])CC(=O)NCCCN1CCN(Cc2ccccc2)CC1 nan
CHEMBL1300302 19622 None 5 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 528 11 1 6 3.9 Cc1oc(-c2ccc(Cl)cc2)nc1C[S+]([O-])CC(=O)NCCCN1CCN(Cc2ccccc2)CC1 nan
71821 45315 None 26 Human Functional pIC50 = 6.7 6.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 256 2 0 2 4.0 Cc1nc2ccccc2n1Cc1ccc(Cl)cc1 nan
CHEMBL152649 45315 None 26 Human Functional pIC50 = 6.7 6.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 256 2 0 2 4.0 Cc1nc2ccccc2n1Cc1ccc(Cl)cc1 nan
936105 46171 None 9 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 332 4 1 4 2.4 O=S(=O)(NCc1ccncc1)c1ccc(Br)s1 nan
CHEMBL1534042 46171 None 9 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 332 4 1 4 2.4 O=S(=O)(NCc1ccncc1)c1ccc(Br)s1 nan
3236301 37530 None 6 Human Functional pIC50 = 5.7 5.7 4 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 1 1 7 -0.3 CCc1nc2c([nH]1)c1no[n+]([O-])c1c1no[n+]([O-])c21 nan
CHEMBL1455957 37530 None 6 Human Functional pIC50 = 5.7 5.7 4 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 1 1 7 -0.3 CCc1nc2c([nH]1)c1no[n+]([O-])c1c1no[n+]([O-])c21 nan
2100274 24729 None 1 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 418 3 0 8 2.0 O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(c2ncnc3sccc23)CC1 nan
CHEMBL1344025 24729 None 1 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 418 3 0 8 2.0 O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(c2ncnc3sccc23)CC1 nan
2795678 51739 None 2 Human Functional pIC50 = 5.7 5.7 4 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 434 2 1 4 5.7 Cc1cccc(Cl)c1NC(=O)N1CCCN(c2nc3ccc(Cl)cc3s2)CC1 nan
CHEMBL1584471 51739 None 2 Human Functional pIC50 = 5.7 5.7 4 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 434 2 1 4 5.7 Cc1cccc(Cl)c1NC(=O)N1CCCN(c2nc3ccc(Cl)cc3s2)CC1 nan
2738599 45064 None 2 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 6 1 4 3.1 CN1CCN(c2ccc(CNS(=O)(=O)Cc3cccc(C(F)(F)F)c3)cc2)CC1 nan
CHEMBL1524322 45064 None 2 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 427 6 1 4 3.1 CN1CCN(c2ccc(CNS(=O)(=O)Cc3cccc(C(F)(F)F)c3)cc2)CC1 nan
3323365 40028 None 12 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 3 1 4 4.4 Cc1nn(C)c(Cl)c1NC(=O)OCc1ccc(Cl)cc1Cl nan
CHEMBL1478769 40028 None 12 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 3 1 4 4.4 Cc1nn(C)c(Cl)c1NC(=O)OCc1ccc(Cl)cc1Cl nan
3237836 44988 None 5 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 3 1 6 3.1 N#CCSc1nc(N)c(C#N)c(C2CCCCC2)c1C#N nan
CHEMBL1523520 44988 None 5 Human Functional pIC50 = 5.7 5.7 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 297 3 1 6 3.1 N#CCSc1nc(N)c(C#N)c(C2CCCCC2)c1C#N nan
663916 38236 None 5 Human Functional pIC50 = 5.7 5.7 3 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 259 4 1 3 3.4 CCCCOc1[nH]cnc2c3cc(F)ccc3nc1-2 nan
CHEMBL1462076 38236 None 5 Human Functional pIC50 = 5.7 5.7 3 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 259 4 1 3 3.4 CCCCOc1[nH]cnc2c3cc(F)ccc3nc1-2 nan
1653621 22486 None 15 Human Functional pIC50 = 5.6 5.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 298 6 1 3 4.6 CCCOc1ccc(CSc2nc3ccccc3[nH]2)cc1 nan
CHEMBL1325226 22486 None 15 Human Functional pIC50 = 5.6 5.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 298 6 1 3 4.6 CCCOc1ccc(CSc2nc3ccccc3[nH]2)cc1 nan
4352110 26590 None 6 Human Functional pIC50 = 5.6 5.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 3 4 9 2.3 COc1ccc(C2CC(=O)Nc3sc(=N)c4c(N)c(C#N)c(N)nc4c32)cc1OC nan
CHEMBL1361038 26590 None 6 Human Functional pIC50 = 5.6 5.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 422 3 4 9 2.3 COc1ccc(C2CC(=O)Nc3sc(=N)c4c(N)c(C#N)c(N)nc4c32)cc1OC nan
24793944 41771 None 1 Human Functional pIC50 = 6.6 6.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 357 3 1 5 2.7 Cn1nccc1C(=O)NC1CCCc2c1cnn2-c1ccc(F)cc1F nan
CHEMBL1492752 41771 None 1 Human Functional pIC50 = 6.6 6.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 357 3 1 5 2.7 Cn1nccc1C(=O)NC1CCCc2c1cnn2-c1ccc(F)cc1F nan
616573 4600 None 20 Human Functional pIC50 = 5.6 5.6 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
CHEMBL102726 4600 None 20 Human Functional pIC50 = 5.6 5.6 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
CHEMBL1444764 4600 None 20 Human Functional pIC50 = 5.6 5.6 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 235 3 1 3 3.2 c1ccc(CNc2ncnc3ccccc23)cc1 nan
16196224 55500 None 0 Human Functional pIC50 = 6.6 6.6 51 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccc(N2C(C)=CC(=Cc3sc4ccccc4[n+]3C)C=C2C)cc1 nan
2320816 55500 None 0 Human Functional pIC50 = 6.6 6.6 51 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccc(N2C(C)=CC(=Cc3sc4ccccc4[n+]3C)C=C2C)cc1 nan
5668087 55500 None 0 Human Functional pIC50 = 6.6 6.6 51 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccc(N2C(C)=CC(=Cc3sc4ccccc4[n+]3C)C=C2C)cc1 nan
CHEMBL1422429 55500 None 0 Human Functional pIC50 = 6.6 6.6 51 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccc(N2C(C)=CC(=Cc3sc4ccccc4[n+]3C)C=C2C)cc1 nan
CHEMBL1620064 55500 None 0 Human Functional pIC50 = 6.6 6.6 51 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 3 0 3 5.4 COc1ccc(N2C(C)=CC(=Cc3sc4ccccc4[n+]3C)C=C2C)cc1 nan
3111187 47561 None 30 Human Functional pIC50 = 6.6 6.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 248 2 2 5 1.0 CC1CC(=O)NN=C1c1ccc(N)c([N+](=O)[O-])c1 nan
CHEMBL1546066 47561 None 30 Human Functional pIC50 = 6.6 6.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 248 2 2 5 1.0 CC1CC(=O)NN=C1c1ccc(N)c([N+](=O)[O-])c1 nan
1095440 44220 None 10 Human Functional pIC50 = 5.6 5.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 359 6 2 3 3.7 CC(=O)c1cn(CC(=O)NCCc2c[nH]c3ccccc23)c2ccccc12 nan
CHEMBL1516566 44220 None 10 Human Functional pIC50 = 5.6 5.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 359 6 2 3 3.7 CC(=O)c1cn(CC(=O)NCCc2c[nH]c3ccccc23)c2ccccc12 nan
20919845 31348 None 5 Human Functional pIC50 = 5.6 5.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 475 8 1 8 2.9 COc1ccc(OC)c(CCNC(=O)Cn2nc(C)c3c(C)n(-c4ccc(C)cc4)nc3c2=O)c1 nan
CHEMBL1401965 31348 None 5 Human Functional pIC50 = 5.6 5.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 475 8 1 8 2.9 COc1ccc(OC)c(CCNC(=O)Cn2nc(C)c3c(C)n(-c4ccc(C)cc4)nc3c2=O)c1 nan
16190638 53679 None 2 Human Functional pIC50 = 5.6 5.6 9 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 5 1 4 4.0 CCC1C(=O)NCCN1Cc1nc(-c2ccc(-c3ccccc3)cc2)oc1C nan
CHEMBL1603032 53679 None 2 Human Functional pIC50 = 5.6 5.6 9 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 375 5 1 4 4.0 CCC1C(=O)NCCN1Cc1nc(-c2ccc(-c3ccccc3)cc2)oc1C nan
23723905 59655 None 5 Human Functional pIC50 = 5.6 5.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 391 6 1 5 3.9 CC(C)(C)CN1CCN(Cc2nc(-c3ccc(F)cc3)cs2)CC1CCO nan
CHEMBL1720771 59655 None 5 Human Functional pIC50 = 5.6 5.6 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 391 6 1 5 3.9 CC(C)(C)CN1CCN(Cc2nc(-c3ccc(F)cc3)cs2)CC1CCO nan
44246639 59571 None 0 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 484 7 0 7 3.7 Cc1cc(C)c(CN2CCN(C(=O)Cn3cnc4c(OCc5ccccc5)ncnc43)CC2)c(C)c1 nan
CHEMBL1717082 59571 None 0 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 484 7 0 7 3.7 Cc1cc(C)c(CN2CCN(C(=O)Cn3cnc4c(OCc5ccccc5)ncnc43)CC2)c(C)c1 nan
2534514 59313 None 2 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 357 6 2 4 2.7 O=C(COC(=O)c1[nH]nc2ccccc12)NCCc1ccc(Cl)cc1 nan
CHEMBL1705059 59313 None 2 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 357 6 2 4 2.7 O=C(COC(=O)c1[nH]nc2ccccc12)NCCc1ccc(Cl)cc1 nan
135399075 19824 None 4 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 420 7 2 8 3.7 Cc1cc(C(=O)CSc2nc(N)cc(O)n2)c(C)n1-c1ccc(OC(F)F)cc1 nan
CHEMBL1301887 19824 None 4 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 420 7 2 8 3.7 Cc1cc(C(=O)CSc2nc(N)cc(O)n2)c(C)n1-c1ccc(OC(F)F)cc1 nan
1163593 53310 None 6 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 481 8 2 6 3.6 COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(CN4CCOCC4)cc3)cc2)cc1 nan
CHEMBL1599462 53310 None 6 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 481 8 2 6 3.6 COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(CN4CCOCC4)cc3)cc2)cc1 nan
2548270 49804 None 6 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 362 5 2 6 2.6 Cc1sc2ncnc(NCCc3ccc(S(N)(=O)=O)cc3)c2c1C nan
CHEMBL1567331 49804 None 6 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 362 5 2 6 2.6 Cc1sc2ncnc(NCCc3ccc(S(N)(=O)=O)cc3)c2c1C nan
108144 210141 None 50 Human Functional pIC50 = 6.5 6.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 423 5 2 6 3.2 NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N nan
CHEMBL95431 210141 None 50 Human Functional pIC50 = 6.5 6.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 423 5 2 6 3.2 NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N nan
951643 47938 None 5 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 274 3 0 3 3.8 CC(=O)c1cn(Cc2ccccc2C#N)c2ccccc12 nan
CHEMBL1549500 47938 None 5 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 274 3 0 3 3.8 CC(=O)c1cn(Cc2ccccc2C#N)c2ccccc12 nan
6902566 108237 None 1 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 329 3 2 2 3.8 FC(F)(F)c1cccc(/C=N/NC(=S)NC2CCCCC2)c1 nan
CHEMBL3196315 108237 None 1 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 329 3 2 2 3.8 FC(F)(F)c1cccc(/C=N/NC(=S)NC2CCCCC2)c1 nan
646118 31957 None 3 Human Functional pIC50 = 5.5 5.5 5 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 311 6 1 6 2.7 CCc1c(C)nc2ncnn2c1NCCc1ccc(OC)cc1 nan
CHEMBL1407572 31957 None 3 Human Functional pIC50 = 5.5 5.5 5 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 311 6 1 6 2.7 CCc1c(C)nc2ncnn2c1NCCc1ccc(OC)cc1 nan
1321677 34123 None 6 Human Functional pIC50 = 6.5 6.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 432 7 1 4 5.4 Cc1cc(CSc2ccccc2)ccc1NC(=O)c1ccc(CN2CCOCC2)cc1 nan
CHEMBL1425552 34123 None 6 Human Functional pIC50 = 6.5 6.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 432 7 1 4 5.4 Cc1cc(CSc2ccccc2)ccc1NC(=O)c1ccc(CN2CCOCC2)cc1 nan
2139165 53828 None 7 Human Functional pIC50 = 6.5 6.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 236 2 0 2 3.7 Cc1ccccc1Cn1c(C)nc2ccccc21 nan
CHEMBL1604200 53828 None 7 Human Functional pIC50 = 6.5 6.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 236 2 0 2 3.7 Cc1ccccc1Cn1c(C)nc2ccccc21 nan
135549777 109213 None 4 Human Functional pIC50 = 5.5 5.5 7 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 471 7 1 9 4.1 C/C(=N\OCc1nc2ccccc2c(=O)n1/N=C/c1cc(C)cc([N+](=O)[O-])c1O)c1ccccc1 nan
CHEMBL3214310 109213 None 4 Human Functional pIC50 = 5.5 5.5 7 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 471 7 1 9 4.1 C/C(=N\OCc1nc2ccccc2c(=O)n1/N=C/c1cc(C)cc([N+](=O)[O-])c1O)c1ccccc1 nan
49778246 67637 None 0 Human Functional pIC50 = 6.5 6.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 484 7 2 8 4.2 OC[C@@H]1CN(Cc2ccc(-c3ccccc3)cc2)C[C@H](n2cnc3c(NC4CCCC4)ncnc32)O1 nan
CHEMBL1903414 67637 None 0 Human Functional pIC50 = 6.5 6.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 484 7 2 8 4.2 OC[C@@H]1CN(Cc2ccc(-c3ccccc3)cc2)C[C@H](n2cnc3c(NC4CCCC4)ncnc32)O1 nan
4143977 59547 None 3 Human Functional pIC50 = 5.5 5.5 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 461 7 1 7 4.6 COCC(C)n1c(-c2ccc3c(c2)NC(=O)CO3)cs/c1=N\c1ccc(OC(F)F)cc1 nan
CHEMBL1716038 59547 None 3 Human Functional pIC50 = 5.5 5.5 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 461 7 1 7 4.6 COCC(C)n1c(-c2ccc3c(c2)NC(=O)CO3)cs/c1=N\c1ccc(OC(F)F)cc1 nan
16397324 42596 None 4 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 435 14 2 4 4.8 CCCCC[C@H](O)/C=C/[C@H]1CCC(=O)[C@@H]1CCCCCCC(=O)N1CCCCC1CO nan
CHEMBL1500445 42596 None 4 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 435 14 2 4 4.8 CCCCC[C@H](O)/C=C/[C@H]1CCC(=O)[C@@H]1CCCCCCC(=O)N1CCCCC1CO nan
693933 47744 None 8 Human Functional pIC50 = 5.5 5.5 3 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 327 3 1 3 3.9 Nc1cc(-c2ccc(Br)cc2)nn1Cc1ccccc1 nan
CHEMBL1547757 47744 None 8 Human Functional pIC50 = 5.5 5.5 3 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 327 3 1 3 3.9 Nc1cc(-c2ccc(Br)cc2)nn1Cc1ccccc1 nan
24819426 51633 None 2 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 435 7 1 5 4.9 COc1ccc(CN2CCC(C(=O)Nc3ccc(Oc4ccccc4)nc3)CC2)cc1F nan
CHEMBL1583610 51633 None 2 Human Functional pIC50 = 5.5 5.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 435 7 1 5 4.9 COc1ccc(CN2CCC(C(=O)Nc3ccc(Oc4ccccc4)nc3)CC2)cc1F nan
46943517 72260 None 0 Human Functional pIC50 = 6.5 6.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 431 7 1 5 5.4 COc1ccc(-c2coc3c(C(=O)NCc4ccc(OC)c(OC)c4)cccc23)c(C)c1 nan
CHEMBL1981589 72260 None 0 Human Functional pIC50 = 6.5 6.5 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 431 7 1 5 5.4 COc1ccc(-c2coc3c(C(=O)NCc4ccc(OC)c(OC)c4)cccc23)c(C)c1 nan
44601539 59458 None 0 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 483 7 1 7 3.7 Cc1cc(C)c(CN2CCN(C(=O)Cn3cnc4c(NCc5ccccc5)ncnc43)CC2)c(C)c1 nan
CHEMBL1711360 59458 None 0 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 483 7 1 7 3.7 Cc1cc(C)c(CN2CCN(C(=O)Cn3cnc4c(NCc5ccccc5)ncnc43)CC2)c(C)c1 nan
3695590 50054 None 11 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 292 5 3 6 0.9 CC1CC(=O)NN=C1c1ccc(NCCO)c([N+](=O)[O-])c1 nan
CHEMBL1569489 50054 None 11 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 292 5 3 6 0.9 CC1CC(=O)NN=C1c1ccc(NCCO)c([N+](=O)[O-])c1 nan
417935 55146 None 0 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 275 1 0 1 3.8 CC1(C)CC(N2CCCCC2)=CC(=[N+]2CCCCC2)C1 nan
CHEMBL1342790 55146 None 0 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 275 1 0 1 3.8 CC1(C)CC(N2CCCCC2)=CC(=[N+]2CCCCC2)C1 nan
CHEMBL1617098 55146 None 0 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 275 1 0 1 3.8 CC1(C)CC(N2CCCCC2)=CC(=[N+]2CCCCC2)C1 nan
2128618 23984 None 3 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 353 7 0 6 3.3 COCCn1c(C)cc(C(=O)COc2nc3ccccc3nc2C)c1C nan
CHEMBL1337567 23984 None 3 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 353 7 0 6 3.3 COCCn1c(C)cc(C(=O)COc2nc3ccccc3nc2C)c1C nan
135431504 44628 None 7 Human Functional pIC50 = 5.4 5.4 3 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 308 2 2 7 3.3 Nc1nn2c(O)c3c(nc2c1N=Nc1ccccc1)CCCC3 nan
CHEMBL1520388 44628 None 7 Human Functional pIC50 = 5.4 5.4 3 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 308 2 2 7 3.3 Nc1nn2c(O)c3c(nc2c1N=Nc1ccccc1)CCCC3 nan
2100093 33909 None 11 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 315 6 1 6 3.4 COc1ccc(CCNc2ncnc3sccc23)cc1OC nan
CHEMBL1423660 33909 None 11 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 315 6 1 6 3.4 COc1ccc(CCNc2ncnc3sccc23)cc1OC nan
2326905 19654 None 3 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 310 4 1 3 4.8 CNc1ccccc1C(C)(C)c1cc(-c2ccc(F)cc2)no1 nan
CHEMBL1300536 19654 None 3 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 310 4 1 3 4.8 CNc1ccccc1C(C)(C)c1cc(-c2ccc(F)cc2)no1 nan
663797 31156 None 5 Human Functional pIC50 = 6.4 6.4 104 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.4 COc1cccc2[nH]c3c(N4CCC(C)CC4)ncnc3c12 nan
CHEMBL1400272 31156 None 5 Human Functional pIC50 = 6.4 6.4 104 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.4 COc1cccc2[nH]c3c(N4CCC(C)CC4)ncnc3c12 nan
4323685 59670 None 7 Human Functional pIC50 = 7.4 7.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 3 0 6 3.8 COc1cc2c(cc1OC)C1C(=O)c3ccc4c(c3OC1CO2)CC(C(C)C)O4 nan
CHEMBL1721226 59670 None 7 Human Functional pIC50 = 7.4 7.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 396 3 0 6 3.8 COc1cc2c(cc1OC)C1C(=O)c3ccc4c(c3OC1CO2)CC(C(C)C)O4 nan
944164 34480 None 5 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 292 4 2 3 4.4 C1=C(CCNc2[nH]cnc3c4ccccc4nc2-3)CCCC1 nan
CHEMBL1428566 34480 None 5 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 292 4 2 3 4.4 C1=C(CCNc2[nH]cnc3c4ccccc4nc2-3)CCCC1 nan
3548924 27937 None 4 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 358 5 1 7 2.6 CCOC(=O)Cc1csc(NC(=O)c2cc(=O)c3ccccc3o2)n1 nan
CHEMBL1371941 27937 None 4 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 358 5 1 7 2.6 CCOC(=O)Cc1csc(NC(=O)c2cc(=O)c3ccccc3o2)n1 nan
1218 3616 None 23 Human Functional pIC50 = 5.4 5.4 -2691 4
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 289 1 3 3 3.0 Oc1c(O)cc2c(c1Cl)CCNCC2c1ccccc1 nan
938 3616 None 23 Human Functional pIC50 = 5.4 5.4 -2691 4
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 289 1 3 3 3.0 Oc1c(O)cc2c(c1Cl)CCNCC2c1ccccc1 nan
CHEMBL353335 3616 None 23 Human Functional pIC50 = 5.4 5.4 -2691 4
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 289 1 3 3 3.0 Oc1c(O)cc2c(c1Cl)CCNCC2c1ccccc1 nan
3380750 109218 None 11 Human Functional pIC50 = 5.4 5.4 3 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 521 5 1 6 6.9 CO/C(O)=C1\C(C)=NC2=C(C(=O)CCC2)C1c1cn(Cc2ccc(Cl)cc2Cl)nc1-c1ccccc1 nan
CHEMBL3214406 109218 None 11 Human Functional pIC50 = 5.4 5.4 3 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 521 5 1 6 6.9 CO/C(O)=C1\C(C)=NC2=C(C(=O)CCC2)C1c1cn(Cc2ccc(Cl)cc2Cl)nc1-c1ccccc1 nan
53382850 80245 None 0 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 353 4 2 3 4.4 Nc1nc2ccccc2cc1C(=O)NCc1ccc(-c2ccccc2)cc1 nan
CHEMBL2136916 80245 None 0 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 353 4 2 3 4.4 Nc1nc2ccccc2cc1C(=O)NCc1ccc(-c2ccccc2)cc1 nan
51360281 80106 None 0 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 453 4 3 10 0.1 CN(Cc1ccc2c(c1)CCCN2C)C(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O nan
CHEMBL2130641 80106 None 0 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 453 4 3 10 0.1 CN(Cc1ccc2c(c1)CCCN2C)C(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O nan
2534340 34019 None 7 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 332 6 1 4 3.3 O=C(COc1ccc(C(=O)c2ccccc2)cc1)Nc1cccnc1 nan
CHEMBL1424583 34019 None 7 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 332 6 1 4 3.3 O=C(COc1ccc(C(=O)c2ccccc2)cc1)Nc1cccnc1 nan
663629 19623 None 5 Human Functional pIC50 = 6.4 6.4 100 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.4 COc1cccc2[nH]c3c(N4CCCC(C)C4)ncnc3c12 nan
CHEMBL1300327 19623 None 5 Human Functional pIC50 = 6.4 6.4 100 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.4 COc1cccc2[nH]c3c(N4CCCC(C)C4)ncnc3c12 nan
49795269 88617 None 0 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 412 6 3 7 3.4 O=C(Nc1ccc(Oc2ccccc2)cc1)c1csc([C@H]2C[C@H](O)[C@@H](CO)O2)n1 nan
CHEMBL2355112 88617 None 0 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 412 6 3 7 3.4 O=C(Nc1ccc(Oc2ccccc2)cc1)c1csc([C@H]2C[C@H](O)[C@@H](CO)O2)n1 nan
4525145 55654 None 2 Human Functional pIC50 = 6.4 6.4 16 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 365 3 0 3 5.5 CC[n+]1c(/C=C2\SC(c3ccccc3C)=CN2C)sc2ccccc21 nan
6140197 55654 None 2 Human Functional pIC50 = 6.4 6.4 16 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 365 3 0 3 5.5 CC[n+]1c(/C=C2\SC(c3ccccc3C)=CN2C)sc2ccccc21 nan
73945770 55654 None 2 Human Functional pIC50 = 6.4 6.4 16 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 365 3 0 3 5.5 CC[n+]1c(/C=C2\SC(c3ccccc3C)=CN2C)sc2ccccc21 nan
CHEMBL1462215 55654 None 2 Human Functional pIC50 = 6.4 6.4 16 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 365 3 0 3 5.5 CC[n+]1c(/C=C2\SC(c3ccccc3C)=CN2C)sc2ccccc21 nan
CHEMBL1621471 55654 None 2 Human Functional pIC50 = 6.4 6.4 16 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 365 3 0 3 5.5 CC[n+]1c(/C=C2\SC(c3ccccc3C)=CN2C)sc2ccccc21 nan
24792082 54569 None 1 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 4 2 4 2.9 CC(C)(C)c1ccc(-n2ncc3c2CCCC3NC(=O)C2(C(N)=O)CC2)cc1 nan
CHEMBL1610300 54569 None 1 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 4 2 4 2.9 CC(C)(C)c1ccc(-n2ncc3c2CCCC3NC(=O)C2(C(N)=O)CC2)cc1 nan
16306739 35343 None 3 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 464 8 0 8 2.2 COc1ccc(CN(C)c2ccc(S(=O)(=O)N3CCN(C)CC3)cc2[N+](=O)[O-])cc1OC nan
CHEMBL1437030 35343 None 3 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 464 8 0 8 2.2 COc1ccc(CN(C)c2ccc(S(=O)(=O)N3CCN(C)CC3)cc2[N+](=O)[O-])cc1OC nan
4143977 59547 None 3 Human Functional pIC50 = 5.4 5.4 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 461 7 1 7 4.6 COCC(C)n1c(-c2ccc3c(c2)NC(=O)CO3)cs/c1=N\c1ccc(OC(F)F)cc1 nan
CHEMBL1716038 59547 None 3 Human Functional pIC50 = 5.4 5.4 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 461 7 1 7 4.6 COCC(C)n1c(-c2ccc3c(c2)NC(=O)CO3)cs/c1=N\c1ccc(OC(F)F)cc1 nan
2229408 56127 None 14 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 329 6 1 6 3.7 COc1ccc(CCNc2ncnc3sc(C)cc23)cc1OC nan
CHEMBL1603001 56127 None 14 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 329 6 1 6 3.7 COc1ccc(CCNc2ncnc3sc(C)cc23)cc1OC nan
CHEMBL1625429 56127 None 14 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 329 6 1 6 3.7 COc1ccc(CCNc2ncnc3sc(C)cc23)cc1OC nan
24790916 31061 None 5 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 433 8 1 8 3.1 CCOC(=O)CCN(c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(O)nn2)s1 nan
CHEMBL1399389 31061 None 5 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 433 8 1 8 3.1 CCOC(=O)CCN(c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(O)nn2)s1 nan
24819837 27350 None 3 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 314 3 1 2 4.2 O=C(Cc1ccc(Cl)cc1Cl)Nc1ccncc1Cl nan
CHEMBL1367597 27350 None 3 Human Functional pIC50 = 5.4 5.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 314 3 1 2 4.2 O=C(Cc1ccc(Cl)cc1Cl)Nc1ccncc1Cl nan
24792017 31693 None 1 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 423 7 0 7 3.8 CCOC(=O)CC1CCCCN1C(=O)c1cc(COc2cccc3cnccc23)on1 nan
CHEMBL1405288 31693 None 1 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 423 7 0 7 3.8 CCOC(=O)CC1CCCCN1C(=O)c1cc(COc2cccc3cnccc23)on1 nan
24980848 41885 None 3 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 524 10 2 7 2.1 CCN(CC)S(=O)(=O)c1cc(NC(=O)CNc2cccc(S(=O)(=O)N3CCOCC3)c2)ccc1C nan
CHEMBL1493864 41885 None 3 Human Functional pIC50 = 6.4 6.4 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 524 10 2 7 2.1 CCN(CC)S(=O)(=O)c1cc(NC(=O)CNc2cccc(S(=O)(=O)N3CCOCC3)c2)ccc1C nan
2552706 32661 None 2 Human Functional pIC50 = 6.3 6.3 20 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 487 6 0 9 5.6 O=c1cc(CSc2nnc(-c3cccs3)n2Cc2ccccc2)nc2sc3ccccc3n12 nan
CHEMBL1413056 32661 None 2 Human Functional pIC50 = 6.3 6.3 20 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 487 6 0 9 5.6 O=c1cc(CSc2nnc(-c3cccs3)n2Cc2ccccc2)nc2sc3ccccc3n12 nan
386315 67339 None 0 Human Functional pIC50 = 6.3 6.3 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 583 7 1 14 1.8 CC(=O)OCC1OC(n2c(S)c(C#N)c(-c3ccccc3)c(C#N)c2=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O nan
CHEMBL1884207 67339 None 0 Human Functional pIC50 = 6.3 6.3 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 583 7 1 14 1.8 CC(=O)OCC1OC(n2c(S)c(C#N)c(-c3ccccc3)c(C#N)c2=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O nan
2311088 55666 None 2 Human Functional pIC50 = 5.3 5.3 1 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 387 3 0 2 5.2 COc1ccc(-[n+]2c(-c3ccc(Cl)cc3)cn3c2CCc2ccccc2-3)cc1 nan
CHEMBL1457690 55666 None 2 Human Functional pIC50 = 5.3 5.3 1 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 387 3 0 2 5.2 COc1ccc(-[n+]2c(-c3ccc(Cl)cc3)cn3c2CCc2ccccc2-3)cc1 nan
CHEMBL1621585 55666 None 2 Human Functional pIC50 = 5.3 5.3 1 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 387 3 0 2 5.2 COc1ccc(-[n+]2c(-c3ccc(Cl)cc3)cn3c2CCc2ccccc2-3)cc1 nan
1245647 36355 None 10 Human Functional pIC50 = 6.3 6.3 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 404 5 2 3 5.0 NC(=O)c1c(-c2ccc(Cl)cc2Cl)csc1NC(=O)Cc1ccccc1 nan
CHEMBL1446412 36355 None 10 Human Functional pIC50 = 6.3 6.3 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 404 5 2 3 5.0 NC(=O)c1c(-c2ccc(Cl)cc2Cl)csc1NC(=O)Cc1ccccc1 nan
1400355 21856 None 6 Human Functional pIC50 = 5.3 5.3 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 377 7 3 4 2.8 CCC(NCCC(c1ccccc1)c1ccccc1)=C1C(=O)NC(=O)NC1=O nan
CHEMBL1319737 21856 None 6 Human Functional pIC50 = 5.3 5.3 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 377 7 3 4 2.8 CCC(NCCC(c1ccccc1)c1ccccc1)=C1C(=O)NC(=O)NC1=O nan
135411696 41924 None 7 Human Functional pIC50 = 6.3 6.3 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 389 4 1 6 4.3 COc1c(/C=C2\SC(Nc3ccccc3Cl)=NC2=O)cccc1[N+](=O)[O-] nan
CHEMBL1494282 41924 None 7 Human Functional pIC50 = 6.3 6.3 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 389 4 1 6 4.3 COc1c(/C=C2\SC(Nc3ccccc3Cl)=NC2=O)cccc1[N+](=O)[O-] nan
20231 33123 None 26 Human Functional pIC50 = 5.3 5.3 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 210 1 1 3 2.6 Cc1nc(O)c(C#N)cc1-c1ccccc1 nan
CHEMBL1417067 33123 None 26 Human Functional pIC50 = 5.3 5.3 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 210 1 1 3 2.6 Cc1nc(O)c(C#N)cc1-c1ccccc1 nan
309279 67227 None 0 Human Functional pIC50 = 5.2 5.2 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 456 4 0 7 5.1 COc1ccc(C2=CC(c3ccc4c(c3)OCO4)c3c(c4ccccc4oc3=O)O2)cc1OC nan
CHEMBL1878306 67227 None 0 Human Functional pIC50 = 5.2 5.2 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 456 4 0 7 5.1 COc1ccc(C2=CC(c3ccc4c(c3)OCO4)c3c(c4ccccc4oc3=O)O2)cc1OC nan
2240759 41448 None 8 Human Functional pIC50 = 6.2 6.2 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 326 6 1 4 2.6 CCOc1cc(S(=O)(=O)NCc2ccncc2)ccc1Cl nan
CHEMBL1490503 41448 None 8 Human Functional pIC50 = 6.2 6.2 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 326 6 1 4 2.6 CCOc1cc(S(=O)(=O)NCc2ccncc2)ccc1Cl nan
2464572 22054 None 3 Human Functional pIC50 = 5.2 5.2 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 460 10 0 7 4.5 COCCn1c(SCCCC(=O)c2ccc(Br)cc2)nnc1-c1ccncc1 nan
CHEMBL1321513 22054 None 3 Human Functional pIC50 = 5.2 5.2 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 460 10 0 7 4.5 COCCn1c(SCCCC(=O)c2ccc(Br)cc2)nnc1-c1ccncc1 nan
91754 85284 None 43 Human Functional pIC50 = 8.2 8.2 2 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 364 3 0 4 5.2 CC(C)(C)c1ccc(CSc2cnn(C(C)(C)C)c(=O)c2Cl)cc1 nan
CHEMBL225963 85284 None 43 Human Functional pIC50 = 8.2 8.2 2 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 364 3 0 4 5.2 CC(C)(C)c1ccc(CSc2cnn(C(C)(C)C)c(=O)c2Cl)cc1 nan
187 255 None 24 Human Functional pIC50 = 6.2 6.2 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
187.0 255 None 24 Human Functional pIC50 = 6.2 6.2 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
294 255 None 24 Human Functional pIC50 = 6.2 6.2 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
65 255 None 24 Human Functional pIC50 = 6.2 6.2 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
8593 255 None 24 Human Functional pIC50 = 6.2 6.2 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
CHEMBL667 255 None 24 Human Functional pIC50 = 6.2 6.2 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
DB03128 255 None 24 Human Functional pIC50 = 6.2 6.2 -22 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 146 3 0 2 0.3 CC(=O)OCC[N+](C)(C)C nan
261711 59579 None 0 Human Functional pIC50 = 6.2 6.2 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 4 2 4 2.7 Cc1ccc(CCNc2ncnc(Cl)c2N)cc1 nan
CHEMBL1717339 59579 None 0 Human Functional pIC50 = 6.2 6.2 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 262 4 2 4 2.7 Cc1ccc(CCNc2ncnc(Cl)c2N)cc1 nan
659242 29847 None 11 Human Functional pIC50 = 5.2 5.2 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 300 2 1 5 3.4 CSc1nc(N)c(C#N)c(-c2ccccc2Cl)c1C#N nan
CHEMBL1387556 29847 None 11 Human Functional pIC50 = 5.2 5.2 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 300 2 1 5 3.4 CSc1nc(N)c(C#N)c(-c2ccccc2Cl)c1C#N nan
1726 2497 None 8 Human Functional pIC50 = 5.1 5.1 -933 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
1993 2497 None 8 Human Functional pIC50 = 5.1 5.1 -933 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
1993.0 2497 None 8 Human Functional pIC50 = 5.1 5.1 -933 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
7438 2497 None 8 Human Functional pIC50 = 5.1 5.1 -933 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
CHEMBL978 2497 None 8 Human Functional pIC50 = 5.1 5.1 -933 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
DB06709 2497 None 8 Human Functional pIC50 = 5.1 5.1 -933 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 160 3 0 2 0.6 CC(C[N+](C)(C)C)OC(=O)C nan
2421595 28545 None 3 Human Functional pIC50 = 6.1 6.1 26 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 417 7 0 7 3.9 COc1ccc(-n2c(C)cc(C(=O)COC(=O)Cn3cnc4ccccc43)c2C)cc1 nan
CHEMBL1376266 28545 None 3 Human Functional pIC50 = 6.1 6.1 26 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 417 7 0 7 3.9 COc1ccc(-n2c(C)cc(C(=O)COC(=O)Cn3cnc4ccccc43)c2C)cc1 nan
4295603 29009 None 4 Human Functional pIC50 = 6.1 6.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 561 6 1 6 3.5 CC1(C)CC2CC(C)(CN2S(=O)(=O)c2ccc(C(=O)Nc3cccc(S(=O)(=O)N4CCOCC4)c3)cc2)C1 nan
CHEMBL1380444 29009 None 4 Human Functional pIC50 = 6.1 6.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 561 6 1 6 3.5 CC1(C)CC2CC(C)(CN2S(=O)(=O)c2ccc(C(=O)Nc3cccc(S(=O)(=O)N4CCOCC4)c3)cc2)C1 nan
4573346 40003 None 10 Human Functional pIC50 = 5.1 5.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 281 3 2 4 2.6 Cn1c(C(=O)NN)cc2cc(Oc3ccccc3)ccc21 nan
CHEMBL1478533 40003 None 10 Human Functional pIC50 = 5.1 5.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 281 3 2 4 2.6 Cn1c(C(=O)NN)cc2cc(Oc3ccccc3)ccc21 nan
730925 36788 None 7 Human Functional pIC50 = 5.1 5.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 278 3 1 4 3.7 N#Cc1cc(-c2ccccc2)oc1NC(=O)c1ccco1 nan
CHEMBL1449874 36788 None 7 Human Functional pIC50 = 5.1 5.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 278 3 1 4 3.7 N#Cc1cc(-c2ccccc2)oc1NC(=O)c1ccco1 nan
659248 194480 None 8 Human Functional pIC50 = 5.1 5.1 1 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 258 5 1 2 3.5 CCCCCCn1c2c(c(=N)c3c1CCC3)CCC2 nan
CHEMBL528708 194480 None 8 Human Functional pIC50 = 5.1 5.1 1 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 258 5 1 2 3.5 CCCCCCn1c2c(c(=N)c3c1CCC3)CCC2 nan
CHEMBL530291 194480 None 8 Human Functional pIC50 = 5.1 5.1 1 3
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 258 5 1 2 3.5 CCCCCCn1c2c(c(=N)c3c1CCC3)CCC2 nan
53299527 80225 None 0 Human Functional pIC50 = 5.1 5.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 400 3 0 3 5.9 Cc1cc(Br)cn2c(Cc3cccc(Cl)c3)c(-c3ccco3)nc12 nan
CHEMBL2136078 80225 None 0 Human Functional pIC50 = 5.1 5.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 400 3 0 3 5.9 Cc1cc(Br)cn2c(Cc3cccc(Cl)c3)c(-c3ccco3)nc12 nan
2967368 33822 None 9 Human Functional pIC50 = 7.1 7.1 72 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.3 O=C(CSc1nnnn1C1CC2CCC1C2)Nc1ccnc2ccccc12 nan
CHEMBL1423004 33822 None 9 Human Functional pIC50 = 7.1 7.1 72 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.3 O=C(CSc1nnnn1C1CC2CCC1C2)Nc1ccnc2ccccc12 nan
934786 41072 None 7 Human Functional pIC50 = 6.1 6.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 324 4 1 5 3.4 Cc1cc(C)nc(SCC(=O)Nc2ccnc3ccccc23)n1 nan
CHEMBL1487720 41072 None 7 Human Functional pIC50 = 6.1 6.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 324 4 1 5 3.4 Cc1cc(C)nc(SCC(=O)Nc2ccnc3ccccc23)n1 nan
24817872 32614 None 5 Human Functional pIC50 = 6.1 6.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 363 4 1 5 3.5 CCn1cc(C(=O)NC2CCCc3c2cnn3-c2cccc(C)c2C)cn1 nan
CHEMBL1412747 32614 None 5 Human Functional pIC50 = 6.1 6.1 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 363 4 1 5 3.5 CCn1cc(C(=O)NC2CCCc3c2cnn3-c2cccc(C)c2C)cn1 nan
649098 48668 None 4 Human Functional pIC50 = 6.1 6.1 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 7 0 8 3.5 COc1ccc(C(=O)CSc2nnc(Cn3cnc4ccccc43)o2)cc1 nan
CHEMBL1557584 48668 None 4 Human Functional pIC50 = 6.1 6.1 2 2
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 380 7 0 8 3.5 COc1ccc(C(=O)CSc2nnc(Cn3cnc4ccccc43)o2)cc1 nan
31729 208242 None 9 Human Functional pIC50 = 6.0 6.0 -38 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 287 6 4 4 2.4 CC(NCCc1ccc(O)cc1)C(O)c1ccc(O)cc1 nan
CHEMBL83063 208242 None 9 Human Functional pIC50 = 6.0 6.0 -38 8
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 287 6 4 4 2.4 CC(NCCc1ccc(O)cc1)C(O)c1ccc(O)cc1 nan
4412278 47299 None 4 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 561 6 1 6 3.5 CC1(C)CC2CC(C)(CN2S(=O)(=O)c2ccc(C(=O)Nc3ccc(S(=O)(=O)N4CCOCC4)cc3)cc2)C1 nan
CHEMBL1544054 47299 None 4 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 561 6 1 6 3.5 CC1(C)CC2CC(C)(CN2S(=O)(=O)c2ccc(C(=O)Nc3ccc(S(=O)(=O)N4CCOCC4)cc3)cc2)C1 nan
1740950 32828 None 6 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 469 5 1 6 6.3 Cc1ccccc1-c1cc(C(=O)Nc2sc(C(=O)OC(C)C)c(C)c2C#N)c2ccccc2n1 nan
CHEMBL1414465 32828 None 6 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 469 5 1 6 6.3 Cc1ccccc1-c1cc(C(=O)Nc2sc(C(=O)OC(C)C)c(C)c2C#N)c2ccccc2n1 nan
2811624 46084 None 2 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 3 1 5 2.7 Cn1nc(C(C)(C)C)cc1C(=O)NCc1cc(F)cc2c1OCOC2 nan
CHEMBL1533321 46084 None 2 Human Functional pIC50 = 6.0 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 347 3 1 5 2.7 Cn1nc(C(C)(C)C)cc1C(=O)NCc1cc(F)cc2c1OCOC2 nan
2204911 31031 None 6 Human Functional pIC50 = 6 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 360 7 1 3 3.7 CCCCc1ccc(NC(=O)c2ccc(N(C)S(C)(=O)=O)cc2)cc1 nan
CHEMBL1399125 31031 None 6 Human Functional pIC50 = 6 6.0 - 1
PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory) PubChem BioAssay. Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). (Class of assay: confirmatory)
ChEMBL 360 7 1 3 3.7 CCCCc1ccc(NC(=O)c2ccc(N(C)S(C)(=O)=O)cc2)cc1 nan
11417 3648 None 0 Human Functional pEC50 = 6.2 6.2 -3 2
Determined by measuring SRE-luc activity in HEK293-Gqi cells expressing hGALR3.Determined by measuring SRE-luc activity in HEK293-Gqi cells expressing hGALR3.
Guide to Pharmacology None None None None 24517231
16133243 1715 None 0 Rat Functional pIC50 = 7.0 7.0 -851 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399
3593 1715 None 0 Rat Functional pIC50 = 7.0 7.0 -851 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399
101927062 1716 None 20 Human Functional pIC50 = 7.1 7.1 -1174 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
155817445 1716 None 20 Human Functional pIC50 = 7.1 7.1 -1174 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
16133823 1716 None 20 Human Functional pIC50 = 7.1 7.1 -1174 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
3592 1716 None 20 Human Functional pIC50 = 7.1 7.1 -1174 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
44584852 1716 None 20 Human Functional pIC50 = 7.1 7.1 -1174 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
6090 1716 None 20 Human Functional pIC50 = 7.1 7.1 -1174 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
91898917 1716 None 20 Human Functional pIC50 = 7.1 7.1 -1174 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
CHEMBL506553 1716 None 20 Human Functional pIC50 = 7.1 7.1 -1174 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
155817484 1714 None 0 Human Functional pIC50 = 7.9 7.9 -186 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
6117 1714 None 0 Human Functional pIC50 = 7.9 7.9 -186 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
6129 1714 None 0 Human Functional pIC50 = 7.9 7.9 -186 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9832121
3594 1742 None 0 Human Functional pIC50 = 8 8.0 2 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944009
3596 1740 None 0 Rat Functional pIC50 = 8.8 8.8 29 2
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399
131863305 327 None 0 Rat Functional pIC50 > 6 6.0 1 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399
155817486 327 None 0 Rat Functional pIC50 > 6 6.0 1 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399
6123 327 None 0 Rat Functional pIC50 > 6 6.0 1 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20880399


Get vendors


Ligands (move mouse cursor over ligand name to see structure) Receptor Activity Chemical information
Sel. page Common
name		 GPCRdb
ID		 Reference
ligand		 Vendors

 Species

 Assay
Type		 Activity
Type		 Activity
Relation		 Activity
Value		 p-value
(-log)		 Fold
selectivity		 Tested
GPCRs		 Assay
Description		 Source

 Mol
weight		 Rot
Bonds		 H don

 H acc

 LogP

 Smiles

 DOI
CHEMBL503473 216655 None 15 Human Binding pKd = 7.8 7.8 -478 3
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O 10.1021/jm801088x
16132180 1724 None 20 Human Binding pKd = 6.5 6.5 -208 8
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
16133822 1724 None 20 Human Binding pKd = 6.5 6.5 -208 8
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
6087 1724 None 20 Human Binding pKd = 6.5 6.5 -208 8
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
CHEMBL499980 1724 None 20 Human Binding pKd = 6.5 6.5 -208 8
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
CHEMBL526003 218159 None 24 Human Binding pKd = 7.4 7.4 -416 3
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(N)=O 10.1021/jm801088x
155817464 1499 None 0 Human Binding pKd = 7.2 7.2 -173 4
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
3866 1499 None 0 Human Binding pKd = 7.2 7.2 -173 4
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
44587986 1499 None 0 Human Binding pKd = 7.2 7.2 -173 4
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
91934870 1499 None 0 Human Binding pKd = 7.2 7.2 -173 4
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
CHEMBL499179 1499 None 0 Human Binding pKd = 7.2 7.2 -173 4
Binding affinity to human GalR3Binding affinity to human GalR3
ChEMBL None None None None 10.1021/jm801088x
44414120 79886 None 0 Human Binding pKi = 6 6.0 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1ccccc1N1C(=O)/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc21 10.1016/j.bmcl.2006.05.025
CHEMBL212224 79886 None 0 Human Binding pKi = 6 6.0 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1ccccc1N1C(=O)/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc21 10.1016/j.bmcl.2006.05.025
11677898 139343 None 0 Human Binding pKi = 7.8 7.8 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)CC(O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL378991 139343 None 0 Human Binding pKi = 7.8 7.8 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)CC(O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
3561805 80015 None 12 Human Binding pKi = 6.8 6.8 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 330 3 0 2 4.6 C=CCN1C(=O)/C(=N/c2ccc(Cl)c(Cl)c2)c2ccccc21 10.1021/jm060001n
CHEMBL212729 80015 None 12 Human Binding pKi = 6.8 6.8 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 330 3 0 2 4.6 C=CCN1C(=O)/C(=N/c2ccc(Cl)c(Cl)c2)c2ccccc21 10.1021/jm060001n
1471834 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1021/jm060001n
6126 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1021/jm060001n
CHEMBL210288 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1021/jm060001n
1471834 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1016/j.bmcl.2006.05.025
6126 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1016/j.bmcl.2006.05.025
CHEMBL210288 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 10.1016/j.bmcl.2006.05.025
44414299 139312 None 0 Human Binding pKi = 7.7 7.7 19 2
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 495 9 0 4 6.6 CCN(CC)CCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL378825 139312 None 0 Human Binding pKi = 7.7 7.7 19 2
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 495 9 0 4 6.6 CCN(CC)CCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
44414138 79555 None 0 Human Binding pKi = 7.6 7.6 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 453 6 0 4 5.4 CN(C)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL211398 79555 None 0 Human Binding pKi = 7.6 7.6 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 453 6 0 4 5.4 CN(C)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
44414234 77982 None 0 Human Binding pKi = 7.6 7.6 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)C[C@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL209642 77982 None 0 Human Binding pKi = 7.6 7.6 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)C[C@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
44414075 138557 None 0 Human Binding pKi = 7.5 7.5 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 467 7 0 4 5.8 CN(C)CCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL377468 138557 None 0 Human Binding pKi = 7.5 7.5 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 467 7 0 4 5.8 CN(C)CCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
44414225 79698 None 0 Human Binding pKi = 6.5 6.5 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)C[C@@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL211522 79698 None 0 Human Binding pKi = 6.5 6.5 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 511 9 1 5 5.6 CCN(CC)C[C@@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
11540517 80292 None 0 Human Binding pKi = 7.5 7.5 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 495 9 0 4 6.6 CCN(CC)CCCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
CHEMBL213893 80292 None 0 Human Binding pKi = 7.5 7.5 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 495 9 0 4 6.6 CCN(CC)CCCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
44414235 141482 None 0 Human Binding pKi = 7.4 7.4 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 467 7 0 4 6.2 CCN(CC)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL383941 141482 None 0 Human Binding pKi = 7.4 7.4 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 467 7 0 4 6.2 CCN(CC)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
135559217 139323 None 1 Human Binding pKi = 6.4 6.4 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 290 1 1 2 4.1 O=C1Nc2ccccc2/C1=N\c1cccc(Cl)c1Cl 10.1021/jm060001n
CHEMBL378877 139323 None 1 Human Binding pKi = 6.4 6.4 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 290 1 1 2 4.1 O=C1Nc2ccccc2/C1=N\c1cccc(Cl)c1Cl 10.1021/jm060001n
44414058 77952 None 0 Human Binding pKi = 7.4 7.4 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 509 10 0 4 7.0 CCN(CC)CCCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL209476 77952 None 0 Human Binding pKi = 7.4 7.4 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 509 10 0 4 7.0 CCN(CC)CCCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
44414043 78405 None 0 Human Binding pKi = 7.3 7.3 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 493 7 0 4 6.4 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCCN2CCCC2)c1 10.1016/j.bmcl.2006.05.025
CHEMBL211031 78405 None 0 Human Binding pKi = 7.3 7.3 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 493 7 0 4 6.4 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCCN2CCCC2)c1 10.1016/j.bmcl.2006.05.025
11698643 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 10.1016/j.bmcl.2006.05.025
6125 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 10.1016/j.bmcl.2006.05.025
CHEMBL209497 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 10.1016/j.bmcl.2006.05.025
44412817 78489 None 0 Human Binding pKi = 7.3 7.3 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 360 4 0 2 5.4 CCC(CC)N1C(=O)/C(=N/c2ccc(C(F)(F)F)cc2)c2ccccc21 10.1021/jm060001n
CHEMBL211169 78489 None 0 Human Binding pKi = 7.3 7.3 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 360 4 0 2 5.4 CCC(CC)N1C(=O)/C(=N/c2ccc(C(F)(F)F)cc2)c2ccccc21 10.1021/jm060001n
135411930 77955 None 11 Human Binding pKi = 6.2 6.2 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 290 1 1 2 3.8 O=C1Nc2ccccc2/C1=N\c1cccc(C(F)(F)F)c1 10.1021/jm060001n
CHEMBL209480 77955 None 11 Human Binding pKi = 6.2 6.2 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 290 1 1 2 3.8 O=C1Nc2ccccc2/C1=N\c1cccc(C(F)(F)F)c1 10.1021/jm060001n
44414180 138491 None 0 Human Binding pKi = 7.2 7.2 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 509 10 0 4 7.0 CCN(CC)CCCCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
CHEMBL377328 138491 None 0 Human Binding pKi = 7.2 7.2 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 509 10 0 4 7.0 CCN(CC)CCCCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
11677377 79639 None 0 Human Binding pKi = 7.1 7.1 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
CHEMBL211467 79639 None 0 Human Binding pKi = 7.1 7.1 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
44414137 166069 None 0 Human Binding pKi = 6.1 6.1 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 479 6 0 4 6.0 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1ccccc1OCCN1CCCC1 10.1016/j.bmcl.2006.05.025
CHEMBL425250 166069 None 0 Human Binding pKi = 6.1 6.1 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 479 6 0 4 6.0 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1ccccc1OCCN1CCCC1 10.1016/j.bmcl.2006.05.025
11712935 77958 None 0 Human Binding pKi = 8.1 8.1 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 493 6 0 4 6.4 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCN2CCCCC2)c1 10.1016/j.bmcl.2006.05.025
CHEMBL209498 77958 None 0 Human Binding pKi = 8.1 8.1 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 493 6 0 4 6.4 O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCN2CCCCC2)c1 10.1016/j.bmcl.2006.05.025
135411931 78032 None 32 Human Binding pKi = 6.1 6.1 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 256 1 1 2 3.4 O=C1Nc2ccccc2/C1=N\c1ccc(Cl)cc1 10.1021/jm060001n
CHEMBL209737 78032 None 32 Human Binding pKi = 6.1 6.1 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 256 1 1 2 3.4 O=C1Nc2ccccc2/C1=N\c1ccc(Cl)cc1 10.1021/jm060001n
44414042 77956 None 0 Human Binding pKi = 7.1 7.1 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
CHEMBL209481 77956 None 0 Human Binding pKi = 7.1 7.1 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 481 8 0 4 6.2 CCN(CC)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 10.1016/j.bmcl.2006.05.025
11544426 142071 None 0 Human Binding pKi = 7.1 7.1 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 328 2 0 2 3.8 C#CCN1C(=O)/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc21 10.1021/jm060001n
CHEMBL387401 142071 None 0 Human Binding pKi = 7.1 7.1 - 1
Displacement of [125I]galanin from human GAL3Displacement of [125I]galanin from human GAL3
ChEMBL 328 2 0 2 3.8 C#CCN1C(=O)/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc21 10.1021/jm060001n
11698159 78030 None 0 Human Binding pKi = 7.1 7.1 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 453 6 0 4 5.4 CN(C)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
CHEMBL209730 78030 None 0 Human Binding pKi = 7.1 7.1 - 1
Displacement of [125I]galanin from human galanin Gal3 receptorDisplacement of [125I]galanin from human galanin Gal3 receptor
ChEMBL 453 6 0 4 5.4 CN(C)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 10.1016/j.bmcl.2006.05.025
155817484 1714 None 0 Human Binding pKd = 8.7 8.7 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817484 1714 None 0 Human Binding pKd = 8.7 8.7 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6117 1714 None 0 Human Binding pKd = 8.7 8.7 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6117 1714 None 0 Human Binding pKd = 8.7 8.7 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6129 1714 None 0 Human Binding pKd = 8.7 8.7 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6129 1714 None 0 Human Binding pKd = 8.7 8.7 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817484 1714 None 0 Rat Binding pKd = 9.1 9.1 -10 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817484 1714 None 0 Rat Binding pKd = 9.1 9.1 -10 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6117 1714 None 0 Rat Binding pKd = 9.1 9.1 -10 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6117 1714 None 0 Rat Binding pKd = 9.1 9.1 -10 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6129 1714 None 0 Rat Binding pKd = 9.1 9.1 -10 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6129 1714 None 0 Rat Binding pKd = 9.1 9.1 -10 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6074 2442 None 0 Human Binding pKd > 5 5.0 -301 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23192661
None 218550 125I-GALANIN 0 Rat Binding pKi = 8.0 8.0 -27 6
NoneNone
PDSP KiDatabase 418 8 0 4 4.3 CC1=CC=C(C=C1)OCCN(C2=CC=CC=C2OC)C(=O)CN3CCCCC3.Cl None
None 218551 125I-p Galanin 0 Rat Binding pKi = 6 6.0 - 1
NoneNone
PDSP KiDatabase None None None None None
None 218550 125I-GALANIN 0 Human Binding pKi = 7.4 7.4 -37 6
NoneNone
PDSP KiDatabase 418 8 0 4 4.3 CC1=CC=C(C=C1)OCCN(C2=CC=CC=C2OC)C(=O)CN3CCCCC3.Cl None
None 218550 125I-p Galanin 0 Rat Binding pKi = 7.1 7.1 -27 6
NoneNone
PDSP KiDatabase 418 8 0 4 4.3 CC1=CC=C(C=C1)OCCN(C2=CC=CC=C2OC)C(=O)CN3CCCCC3.Cl None
6102 2439 None 0 Human Binding pKi = 6.1 6.1 -30 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21333705
6103 2440 None 0 Human Binding pKi = 6.2 6.2 -18 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21333705
6101 2438 None 0 Human Binding pKi = 6.3 6.3 -75 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19467704
16132180 1724 None 20 Human Binding pKi = 6.5 6.5 -208 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16132180 1724 None 20 Human Binding pKi = 6.5 6.5 -208 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
16133822 1724 None 20 Human Binding pKi = 6.5 6.5 -208 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133822 1724 None 20 Human Binding pKi = 6.5 6.5 -208 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6087 1724 None 20 Human Binding pKi = 6.5 6.5 -208 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6087 1724 None 20 Human Binding pKi = 6.5 6.5 -208 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
CHEMBL499980 1724 None 20 Human Binding pKi = 6.5 6.5 -208 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
CHEMBL499980 1724 None 20 Human Binding pKi = 6.5 6.5 -208 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817474 1728 None 0 Rat Binding pKi = 6.6 6.6 -16 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944007
5357 1728 None 0 Rat Binding pKi = 6.6 6.6 -16 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944007
6104 2441 None 0 Human Binding pKi = 6.6 6.6 -45 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21333705
155817474 1728 None 0 Human Binding pKi = 6.7 6.7 -12 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19467704
5357 1728 None 0 Human Binding pKi = 6.7 6.7 -12 5
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19467704
3899 2447 None 0 Human Binding pKi = 6.9 6.9 -933 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3899 2447 None 0 Human Binding pKi = 6.9 6.9 -933 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6075 2108 None 0 Human Binding pKi = 7.0 7.0 -5 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23600864
101927062 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
101927062 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817445 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817445 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
16133823 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133823 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
3592 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3592 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
44584852 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
44584852 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6090 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6090 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
91898917 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
91898917 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
CHEMBL506553 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
CHEMBL506553 1716 None 20 Human Binding pKi = 7.2 7.2 -239 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
16132180 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
16132180 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16132180 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
16133822 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
16133822 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133822 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
6087 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6087 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6087 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
CHEMBL499980 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
CHEMBL499980 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
CHEMBL499980 1724 None 20 Rat Binding pKi = 7.2 7.2 -44 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
3899 2447 None 0 Rat Binding pKi = 7.2 7.2 -501 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944002
3899 2447 None 0 Rat Binding pKi = 7.2 7.2 -501 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3899 2447 None 0 Rat Binding pKi = 7.2 7.2 -501 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817487 1729 None 0 Human Binding pKi = 7.2 7.2 -20 4
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6130 1729 None 0 Human Binding pKi = 7.2 7.2 -20 4
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
101927062 1716 None 20 Rat Binding pKi = 7.3 7.3 -181 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817445 1716 None 20 Rat Binding pKi = 7.3 7.3 -181 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133823 1716 None 20 Rat Binding pKi = 7.3 7.3 -181 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3592 1716 None 20 Rat Binding pKi = 7.3 7.3 -181 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
44584852 1716 None 20 Rat Binding pKi = 7.3 7.3 -181 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6090 1716 None 20 Rat Binding pKi = 7.3 7.3 -181 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
91898917 1716 None 20 Rat Binding pKi = 7.3 7.3 -181 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
CHEMBL506553 1716 None 20 Rat Binding pKi = 7.3 7.3 -181 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6100 2449 None 0 Human Binding pKi = 7.3 7.3 -213 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None None
3896 2443 None 0 Human Binding pKi = 7.4 7.4 -380 7
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3896 2443 None 0 Human Binding pKi = 7.4 7.4 -380 7
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817479 1736 None 0 Human Binding pKi = 7.5 7.5 -14 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817479 1736 None 0 Human Binding pKi = 7.5 7.5 -14 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6083 1736 None 0 Human Binding pKi = 7.5 7.5 -14 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6083 1736 None 0 Human Binding pKi = 7.5 7.5 -14 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817479 1736 None 0 Rat Binding pKi = 7.5 7.5 -12 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6083 1736 None 0 Rat Binding pKi = 7.5 7.5 -12 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3896 2443 None 0 Rat Binding pKi = 7.5 7.5 -281 7
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944002
3896 2443 None 0 Rat Binding pKi = 7.5 7.5 -281 7
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3896 2443 None 0 Rat Binding pKi = 7.5 7.5 -281 7
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6146 337 None 0 Rat Binding pKi = 7.8 7.8 - 1
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6127 1761 None 0 Rat Binding pKi = 7.8 7.8 575 3
UnclassifiedUnclassified
Guide to Pharmacology 397 3 0 4 5.2 COc1ccc(cn1)N1C(=O)/C(=N/c2ccc(c(c2)Cl)Cl)/c2c1cccc2 15944002
9800980 1761 None 0 Rat Binding pKi = 7.8 7.8 575 3
UnclassifiedUnclassified
Guide to Pharmacology 397 3 0 4 5.2 COc1ccc(cn1)N1C(=O)/C(=N/c2ccc(c(c2)Cl)Cl)/c2c1cccc2 15944002
1471834 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16287967
1471834 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16730981
1471834 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16789730
6126 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16287967
6126 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16730981
6126 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16789730
CHEMBL210288 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16287967
CHEMBL210288 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16730981
CHEMBL210288 3629 None 40 Human Binding pKi = 7.8 7.8 4 3
UnclassifiedUnclassified
Guide to Pharmacology 366 2 0 2 5.5 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1ccccc1)cccc2 16789730
3898 2446 None 0 Human Binding pKi = 7.8 7.8 -63 7
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3898 2446 None 0 Human Binding pKi = 7.8 7.8 -63 7
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6076 2109 None 0 Human Binding pKi = 7.9 7.9 -2 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23600864
155817465 1730 None 0 Rat Binding pKi = 7.9 7.9 -13 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817465 1730 None 0 Rat Binding pKi = 7.9 7.9 -13 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
3876 1730 None 0 Rat Binding pKi = 7.9 7.9 -13 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3876 1730 None 0 Rat Binding pKi = 7.9 7.9 -13 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
155817484 1714 None 0 Human Binding pKi = 8.0 8.0 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817484 1714 None 0 Human Binding pKi = 8.0 8.0 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6117 1714 None 0 Human Binding pKi = 8.0 8.0 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6117 1714 None 0 Human Binding pKi = 8.0 8.0 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6129 1714 None 0 Human Binding pKi = 8.0 8.0 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6129 1714 None 0 Human Binding pKi = 8.0 8.0 -22 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817463 777 None 0 Human Binding pKi = 8.1 8.1 -34 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817463 777 None 0 Human Binding pKi = 8.1 8.1 -34 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
3861 777 None 0 Human Binding pKi = 8.1 8.1 -34 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3861 777 None 0 Human Binding pKi = 8.1 8.1 -34 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
16133243 1715 None 0 Human Binding pKi = 8.1 8.1 -51 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19467704
16133243 1715 None 0 Human Binding pKi = 8.1 8.1 -51 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21333705
16133243 1715 None 0 Human Binding pKi = 8.1 8.1 -51 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133243 1715 None 0 Human Binding pKi = 8.1 8.1 -51 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
3593 1715 None 0 Human Binding pKi = 8.1 8.1 -51 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19467704
3593 1715 None 0 Human Binding pKi = 8.1 8.1 -51 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21333705
3593 1715 None 0 Human Binding pKi = 8.1 8.1 -51 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3593 1715 None 0 Human Binding pKi = 8.1 8.1 -51 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817484 1714 None 0 Rat Binding pKi = 8.1 8.1 -10 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6117 1714 None 0 Rat Binding pKi = 8.1 8.1 -10 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6129 1714 None 0 Rat Binding pKi = 8.1 8.1 -10 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6139 1726 None 0 Rat Binding pKi = 8.2 8.2 -1 2
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3897 2445 None 0 Human Binding pKi = 8.2 8.2 -27 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3897 2445 None 0 Human Binding pKi = 8.2 8.2 -27 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
11698643 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16287967
11698643 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16730981
11698643 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16789730
6125 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16287967
6125 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16730981
6125 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16789730
CHEMBL209497 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16287967
CHEMBL209497 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16730981
CHEMBL209497 3630 None 12 Human Binding pKi = 8.3 8.3 15 4
UnclassifiedUnclassified
Guide to Pharmacology 479 6 0 4 6.0 O=C1C(=Nc2cccc(c2)C(F)(F)F)c2c(N1c1cccc(c1)OCCN1CCCC1)cccc2 16789730
3898 2446 None 0 Rat Binding pKi = 8.4 8.4 -16 7
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944002
3898 2446 None 0 Rat Binding pKi = 8.4 8.4 -16 7
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3898 2446 None 0 Rat Binding pKi = 8.4 8.4 -16 7
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133243 1715 None 0 Rat Binding pKi = 8.5 8.5 -22 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944002
16133243 1715 None 0 Rat Binding pKi = 8.5 8.5 -22 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
16133243 1715 None 0 Rat Binding pKi = 8.5 8.5 -22 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
16133243 1715 None 0 Rat Binding pKi = 8.5 8.5 -22 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
3593 1715 None 0 Rat Binding pKi = 8.5 8.5 -22 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15944002
3593 1715 None 0 Rat Binding pKi = 8.5 8.5 -22 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3593 1715 None 0 Rat Binding pKi = 8.5 8.5 -22 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3593 1715 None 0 Rat Binding pKi = 8.5 8.5 -22 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
155817463 777 None 0 Rat Binding pKi = 8.7 8.7 -7 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817463 777 None 0 Rat Binding pKi = 8.7 8.7 -7 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3861 777 None 0 Rat Binding pKi = 8.7 8.7 -7 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
3861 777 None 0 Rat Binding pKi = 8.7 8.7 -7 8
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
3897 2445 None 0 Rat Binding pKi = 8.9 8.9 -5 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6074 2442 None 0 Human Binding pKi > 5 5.0 -301 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23192661
3900 2451 None 0 Human Binding pKi > 5 5.0 -758 3
UnclassifiedUnclassified
Guide to Pharmacology None None None None None
6133 1494 None 0 Rat Binding pKi > 6 6.0 1 2
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817483 1717 None 0 Rat Binding pKi > 6 6.0 1 2
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6094 1717 None 0 Rat Binding pKi > 6 6.0 1 2
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817480 1731 None 0 Human Binding pKi > 6 6.0 -1 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817480 1731 None 0 Human Binding pKi > 6 6.0 -1 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
155817480 1731 None 0 Rat Binding pKi > 6 6.0 -1 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6091 1731 None 0 Human Binding pKi > 6 6.0 -1 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6091 1731 None 0 Human Binding pKi > 6 6.0 -1 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084
6091 1731 None 0 Rat Binding pKi > 6 6.0 -1 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
155817481 1732 None 0 Rat Binding pKi > 6 6.0 -1 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
155817481 1732 None 0 Rat Binding pKi > 6 6.0 -1 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
6092 1732 None 0 Rat Binding pKi > 6 6.0 -1 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9405385
6092 1732 None 0 Rat Binding pKi > 6 6.0 -1 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9742938
6095 1739 None 0 Human Binding pKi > 6 6.0 -72 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6095 1739 None 0 Rat Binding pKi > 6 6.0 -72 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9722565
6095 1739 None 0 Rat Binding pKi > 6 6.0 -72 6
UnclassifiedUnclassified
Guide to Pharmacology None None None None 9880084