Ligand source activities (1 row/activity)



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Ligands (move mouse cursor over ligand name to see structure) Receptor Activity Chemical information
Sel. page Common
name		 GPCRdb
ID		 Reference
ligand		 Vendors

 Species

 Assay
Type

 Activity
Type		 Activity
Relation		 Activity
Value		 p-value
(-log)		 Fold
selectivity		 Tested
GPCRs		 Assay
Description		 Source

 Mol
weight		 Rot
Bonds		 H don

 H acc

 LogP

 Smiles

 DOI
10567 1837 None 0 Human Functional pEC50 = 5.9 5.9 1 3
Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin.Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin.
Guide to Pharmacology None None None None 28900043
145996510 1837 None 0 Human Functional pEC50 = 5.9 5.9 1 3
Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin.Agonist activity determined in vitro, measuring calcium response in CHO-K1 cells expressing hGPR15 and Aequorin.
Guide to Pharmacology None None None None 28900043
10568 1838 None 0 Human Functional pEC50 = 6.8 6.8 - 1
UnclassifiedUnclassified
Guide to Pharmacology None None None None 31675498
145996511 1838 None 0 Human Functional pEC50 = 6.8 6.8 - 1
UnclassifiedUnclassified
Guide to Pharmacology None None None None 31675498


Get vendors


Ligands (move mouse cursor over ligand name to see structure) Receptor Activity Chemical information
Sel. page Common
name		 GPCRdb
ID		 Reference
ligand		 Vendors

 Species

 Assay
Type		 Activity
Type		 Activity
Relation		 Activity
Value		 p-value
(-log)		 Fold
selectivity		 Tested
GPCRs		 Assay
Description		 Source

 Mol
weight		 Rot
Bonds		 H don

 H acc

 LogP

 Smiles

 DOI
CHEMBL5085657 217467 None 0 Human Binding pEC50 = 5.8 5.8 - 0
Activation of human GPR15 stably expressed in CHO cells expressing Aequorin and Galpha16 measured by luminiscence assayActivation of human GPR15 stably expressed in CHO cells expressing Aequorin and Galpha16 measured by luminiscence assay
ChEMBL None None None CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C)C(C)C)C(C)C nan
CHEMBL5085657 217467 None 0 Human Binding pEC50 = 6.0 6.0 - 0
Activation of human GPR15 stably expressed in CHO cells expressing Aequorin measured by luminiscence assayActivation of human GPR15 stably expressed in CHO cells expressing Aequorin measured by luminiscence assay
ChEMBL None None None CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C)C(C)C)C(C)C nan