Ligand source activities (1 row/activity)
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name |
GPCRdb ID |
Reference ligand |
Vendors |
Species |
Assay Type |
Activity Type |
Activity Relation |
Activity Value |
p-value (-log) |
Fold selectivity |
Tested GPCRs |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
|
| 1599 | 2341 | None | 28 | Human | Functional | pEC50 | = | 5.7 | 5.7 | -1096 | 32 | ChEMBL | 476 | 7 | 1 | 3 | 5.1 | Clc1ccc(cc1)C1(O)CCN(CC1)CCC(C(=O)N(C)C)(c1ccccc1)c1ccccc1 | 10.6019/CHEMBL5442687 | |||
| 3955 | 2341 | None | 28 | Human | Functional | pEC50 | = | 5.7 | 5.7 | -1096 | 32 | ChEMBL | 476 | 7 | 1 | 3 | 5.1 | Clc1ccc(cc1)C1(O)CCN(CC1)CCC(C(=O)N(C)C)(c1ccccc1)c1ccccc1 | 10.6019/CHEMBL5442687 | |||
| 3955.0 | 2341 | None | 28 | Human | Functional | pEC50 | = | 5.7 | 5.7 | -1096 | 32 | ChEMBL | 476 | 7 | 1 | 3 | 5.1 | Clc1ccc(cc1)C1(O)CCN(CC1)CCC(C(=O)N(C)C)(c1ccccc1)c1ccccc1 | 10.6019/CHEMBL5442687 | |||
| 7215 | 2341 | None | 28 | Human | Functional | pEC50 | = | 5.7 | 5.7 | -1096 | 32 | ChEMBL | 476 | 7 | 1 | 3 | 5.1 | Clc1ccc(cc1)C1(O)CCN(CC1)CCC(C(=O)N(C)C)(c1ccccc1)c1ccccc1 | 10.6019/CHEMBL5442687 | |||
| CHEMBL841 | 2341 | None | 28 | Human | Functional | pEC50 | = | 5.7 | 5.7 | -1096 | 32 | ChEMBL | 476 | 7 | 1 | 3 | 5.1 | Clc1ccc(cc1)C1(O)CCN(CC1)CCC(C(=O)N(C)C)(c1ccccc1)c1ccccc1 | 10.6019/CHEMBL5442687 | |||
| DB00836 | 2341 | None | 28 | Human | Functional | pEC50 | = | 5.7 | 5.7 | -1096 | 32 | ChEMBL | 476 | 7 | 1 | 3 | 5.1 | Clc1ccc(cc1)C1(O)CCN(CC1)CCC(C(=O)N(C)C)(c1ccccc1)c1ccccc1 | 10.6019/CHEMBL5442687 | |||
| 11316919 | 3068 | None | 31 | Human | Functional | pEC50 | = | 5.7 | 5.7 | -3 | 8 | ChEMBL | 451 | 4 | 0 | 4 | 5.3 | Clc1c(cccc1)n1nc2C(=O)N(CCOc2c1c1ccc(cc1)Cl)CC(C)(F)F | 10.6019/CHEMBL5442687 | |||
| 11693 | 3068 | None | 31 | Human | Functional | pEC50 | = | 5.7 | 5.7 | -3 | 8 | ChEMBL | 451 | 4 | 0 | 4 | 5.3 | Clc1c(cccc1)n1nc2C(=O)N(CCOc2c1c1ccc(cc1)Cl)CC(C)(F)F | 10.6019/CHEMBL5442687 | |||
| CHEMBL484929 | 3068 | None | 31 | Human | Functional | pEC50 | = | 5.7 | 5.7 | -3 | 8 | ChEMBL | 451 | 4 | 0 | 4 | 5.3 | Clc1c(cccc1)n1nc2C(=O)N(CCOc2c1c1ccc(cc1)Cl)CC(C)(F)F | 10.6019/CHEMBL5442687 | |||
| 5311122 | 4068 | None | 4 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -173 | 4 | ChEMBL | 456 | 7 | 0 | 3 | 6.5 | COc1ccc2c(c1)C(CCC2)C(=O)N(c1ccc(cc1)C(C)C)Cc1ccc(cc1)N(C)C | 10.6019/CHEMBL5442687 | |||
| 581 | 4068 | None | 4 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -173 | 4 | ChEMBL | 456 | 7 | 0 | 3 | 6.5 | COc1ccc2c(c1)C(CCC2)C(=O)N(c1ccc(cc1)C(C)C)Cc1ccc(cc1)N(C)C | 10.6019/CHEMBL5442687 | |||
| CHEMBL1628668 | 4068 | None | 4 | Human | Functional | pIC50 | = | 5.7 | 5.7 | -173 | 4 | ChEMBL | 456 | 7 | 0 | 3 | 6.5 | COc1ccc2c(c1)C(CCC2)C(=O)N(c1ccc(cc1)C(C)C)Cc1ccc(cc1)N(C)C | 10.6019/CHEMBL5442687 | |||
| 6603703 | 208 | None | 8 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -870 | 18 | ChEMBL | 329 | 2 | 3 | 4 | 3.3 | NC[C@@H]1O[C@@H](Cc2c1ccc(c2O)O)C12CC3CC(C2)CC(C1)C3 | 10.6019/CHEMBL5442687 | |||
| 9637 | 208 | None | 8 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -870 | 18 | ChEMBL | 329 | 2 | 3 | 4 | 3.3 | NC[C@@H]1O[C@@H](Cc2c1ccc(c2O)O)C12CC3CC(C2)CC(C1)C3 | 10.6019/CHEMBL5442687 | |||
| CHEMBL291143 | 208 | None | 8 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -870 | 18 | ChEMBL | 329 | 2 | 3 | 4 | 3.3 | NC[C@@H]1O[C@@H](Cc2c1ccc(c2O)O)C12CC3CC(C2)CC(C1)C3 | 10.6019/CHEMBL5442687 | |||
| 1692 | 2154 | None | 25 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -93 | 18 | ChEMBL | 411 | 6 | 2 | 4 | 5.5 | CCc1ccc(cc1)OCc1ccccc1C(=O)Nc1ccc2c(c1)c(N)cc(n2)C | 10.6019/CHEMBL5442687 | |||
| 5311340 | 2154 | None | 25 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -93 | 18 | ChEMBL | 411 | 6 | 2 | 4 | 5.5 | CCc1ccc(cc1)OCc1ccccc1C(=O)Nc1ccc2c(c1)c(N)cc(n2)C | 10.6019/CHEMBL5442687 | |||
| CHEMBL140979 | 2154 | None | 25 | Human | Functional | pIC50 | = | 5.6 | 5.6 | -93 | 18 | ChEMBL | 411 | 6 | 2 | 4 | 5.5 | CCc1ccc(cc1)OCc1ccccc1C(=O)Nc1ccc2c(c1)c(N)cc(n2)C | 10.6019/CHEMBL5442687 | |||
| 42611190 | 3156 | None | 14 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -831 | 21 | ChEMBL | 475 | 4 | 2 | 2 | 7.4 | OC(=O)c1cc2cc(ccc2c(c1)c1ccc(cc1)C1CCNCC1)c1ccc(cc1)C(F)(F)F | 10.6019/CHEMBL5442687 | |||
| 5802 | 3156 | None | 14 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -831 | 21 | ChEMBL | 475 | 4 | 2 | 2 | 7.4 | OC(=O)c1cc2cc(ccc2c(c1)c1ccc(cc1)C1CCNCC1)c1ccc(cc1)C(F)(F)F | 10.6019/CHEMBL5442687 | |||
| CHEMBL1800685 | 3156 | None | 14 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -831 | 21 | ChEMBL | 475 | 4 | 2 | 2 | 7.4 | OC(=O)c1cc2cc(ccc2c(c1)c1ccc(cc1)C1CCNCC1)c1ccc(cc1)C(F)(F)F | 10.6019/CHEMBL5442687 | |||
| 2419 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -6025 | 19 | ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | |||
| 5152 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -6025 | 19 | ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | |||
| 5152.0 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -6025 | 19 | ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | |||
| 559 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -6025 | 19 | ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | |||
| CHEMBL1263 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -6025 | 19 | ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | |||
| DB00938 | 3463 | None | 53 | Human | Functional | pIC50 | = | 5.5 | 5.5 | -6025 | 19 | ChEMBL | 415 | 16 | 4 | 5 | 4.1 | OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O | 10.6019/CHEMBL5442687 | |||
| 28 | 3496 | None | 35 | Human | Functional | pIC50 | = | 5.4 | 5.4 | -1 | 15 | ChEMBL | 486 | 9 | 1 | 7 | 5.2 | COc1ccc(cc1OCCN(C)C)NC(=O)c1ccc(cc1)c1ccc(cc1C)c1noc(n1)C | 10.6019/CHEMBL5442687 | |||
| 3292447 | 3496 | None | 35 | Human | Functional | pIC50 | = | 5.4 | 5.4 | -1 | 15 | ChEMBL | 486 | 9 | 1 | 7 | 5.2 | COc1ccc(cc1OCCN(C)C)NC(=O)c1ccc(cc1)c1ccc(cc1C)c1noc(n1)C | 10.6019/CHEMBL5442687 | |||
| CHEMBL20963 | 3496 | None | 35 | Human | Functional | pIC50 | = | 5.4 | 5.4 | -1 | 15 | ChEMBL | 486 | 9 | 1 | 7 | 5.2 | COc1ccc(cc1OCCN(C)C)NC(=O)c1ccc(cc1)c1ccc(cc1C)c1noc(n1)C | 10.6019/CHEMBL5442687 | |||
| 10150497 | 4074 | None | 40 | Human | Functional | pIC50 | = | 5.4 | 5.4 | -630 | 15 | ChEMBL | 380 | 4 | 1 | 7 | 2.7 | NCCc1cn(c2c1cccc2)S(=O)(=O)c1c(Cl)nc2n1ccs2 | 10.6019/CHEMBL5442687 | |||
| 3240 | 4074 | None | 40 | Human | Functional | pIC50 | = | 5.4 | 5.4 | -630 | 15 | ChEMBL | 380 | 4 | 1 | 7 | 2.7 | NCCc1cn(c2c1cccc2)S(=O)(=O)c1c(Cl)nc2n1ccs2 | 10.6019/CHEMBL5442687 | |||
| CHEMBL392760 | 4074 | None | 40 | Human | Functional | pIC50 | = | 5.4 | 5.4 | -630 | 15 | ChEMBL | 380 | 4 | 1 | 7 | 2.7 | NCCc1cn(c2c1cccc2)S(=O)(=O)c1c(Cl)nc2n1ccs2 | 10.6019/CHEMBL5442687 | |||
| 44634573 | 2748 | None | 1 | Human | Functional | pIC50 | = | 5.3 | 5.3 | -588 | 15 | ChEMBL | 465 | 6 | 0 | 2 | 5.0 | Cc1n(C/C=C/c2ccccc2)c2[n+](c1P(=S)(c1ccccc1)c1ccccc1)cccc2 | 10.6019/CHEMBL5442687 | |||
| 9168 | 2748 | None | 1 | Human | Functional | pIC50 | = | 5.3 | 5.3 | -588 | 15 | ChEMBL | 465 | 6 | 0 | 2 | 5.0 | Cc1n(C/C=C/c2ccccc2)c2[n+](c1P(=S)(c1ccccc1)c1ccccc1)cccc2 | 10.6019/CHEMBL5442687 | |||
| CHEMBL1474387 | 2748 | None | 1 | Human | Functional | pIC50 | = | 5.3 | 5.3 | -588 | 15 | ChEMBL | 465 | 6 | 0 | 2 | 5.0 | Cc1n(C/C=C/c2ccccc2)c2[n+](c1P(=S)(c1ccccc1)c1ccccc1)cccc2 | 10.6019/CHEMBL5442687 | |||
| CHEMBL1622930 | 2748 | None | 1 | Human | Functional | pIC50 | = | 5.3 | 5.3 | -588 | 15 | ChEMBL | 465 | 6 | 0 | 2 | 5.0 | Cc1n(C/C=C/c2ccccc2)c2[n+](c1P(=S)(c1ccccc1)c1ccccc1)cccc2 | 10.6019/CHEMBL5442687 | |||
| 662 | 3680 | None | 7 | Human | Functional | pIC50 | = | 5.3 | 5.3 | -2 | 12 | ChEMBL | 756 | 14 | 2 | 8 | 6.3 | COc1ccc2c(c1)ccc(c2)S(=O)(=O)N[C@@H](c1ccc2c(c1)OCO2)CC(=O)N[C@@H](C(=O)N(C(C)C)C)Cc1ccc(cc1)CN1[C@H](C)CCC[C@@H]1C | 10.6019/CHEMBL5442687 | |||
| 9853583 | 3680 | None | 7 | Human | Functional | pIC50 | = | 5.3 | 5.3 | -2 | 12 | ChEMBL | 756 | 14 | 2 | 8 | 6.3 | COc1ccc2c(c1)ccc(c2)S(=O)(=O)N[C@@H](c1ccc2c(c1)OCO2)CC(=O)N[C@@H](C(=O)N(C(C)C)C)Cc1ccc(cc1)CN1[C@H](C)CCC[C@@H]1C | 10.6019/CHEMBL5442687 | |||
| CHEMBL2021721 | 3680 | None | 7 | Human | Functional | pIC50 | = | 5.3 | 5.3 | -2 | 12 | ChEMBL | 756 | 14 | 2 | 8 | 6.3 | COc1ccc2c(c1)ccc(c2)S(=O)(=O)N[C@@H](c1ccc2c(c1)OCO2)CC(=O)N[C@@H](C(=O)N(C(C)C)C)Cc1ccc(cc1)CN1[C@H](C)CCC[C@@H]1C | 10.6019/CHEMBL5442687 | |||
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name |
GPCRdb ID |
Reference ligand |
Vendors |
Species |
Assay Type |
Activity Type |
Activity Relation |
Activity Value |
p-value (-log) |
Fold selectivity |
Tested GPCRs |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
|