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Protein name Generic number Position Segment Mutation FoldChange or Qual Exp Type Ligand Reference Review
Protein name Generic number Segment Position Mutation FoldChange or Qual Exp Type Ligand Reference Review
acm1_human 6.59x59 389 TM6 T => A 1.445↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 2.3↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 3.0↓ IC50 (Binding - Radioligand competition/displacement) Pirenzepine Drubbisch V et al (1993) Vass M et al (2018)
acm1_human 5.39x40 189 TM5 T => A 3.02↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 2.399↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Moro O et al (1994)
acm1_human 7.35x34 400 TM7 W => F 3.715↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.23↑ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 27.778↑ K(l) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 1.096↑ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 7.413↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 4.274↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.24x24 354 TM6 T => A 1.127↑ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 2.041↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.072↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 182 ECL2 F => A 3.02↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.4↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.138↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.23↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.852↓ K(l) (Binding - Radioligand competition/displacement) CDD-0098 Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 50.119↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A >100.0↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P N/A N/A Huang XP et al (1998)
acm1_human 4.69x69 169 TM4 G => A 6.31↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.905↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A 1.758↓ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A N/A N/A Hogger P et al (1995)
acm1_human 3.32x32 105 TM3 D => E 1.585↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Shockley MS et al (1997)
acm1_human 393 ECL3 D => A 2.344↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 7.586↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 11.749↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => F 1.111↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.447↑ K(h) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A N/A N/A Matsui H et al (1995)
acm1_human 5.62x62 212 TM5 Y => A N/A N/A Hogger P et al (1995)
acm1_human 4.65x65 165 TM4 Q => A N/A N/A Matsui H et al (1995)
acm1_human 183 ECL2 L => A 1.82↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 22.909↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.778↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Moro O et al (1994)
acm1_human 2.61x60 82 TM2 Y => F 1.464↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Drubbisch V et al (1993) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 3.548↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.0 pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.39x40 189 TM5 T => A 1.548↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 170 ECL2 E => K 1.148↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => F 6.0↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.778↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 3.548↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A 1.148↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.25↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) p-F-HHSiD Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 8.913↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 1.318↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.24x24 354 TM6 T => A N/A N/A Lameh J et al (1992)
acm1_human 6.52x52 382 TM6 N => A 3.75↓ K(h) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.62x62 212 TM5 Y => A 1.455↓ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.289↑ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 111.111↑ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Hogger P et al (1995)
acm1_human 181 ECL2 Q => A 1.739↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 3.02↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 16.596↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.66↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.29x29 359 TM6 K => A N/A N/A Hogger P et al (1995)
acm1_human 3.28x28 101 TM3 W => A N/A N/A Matsui H et al (1995)
acm1_human 4.65x65 165 TM4 Q => A 1.202↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 4.786↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 19.1↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 7.762↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.071↓ IC50 (Binding - Radioligand competition/displacement) Atropine Drubbisch V et al (1993) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.349↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 4.074↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.148↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.096↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 3.631↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A >100.0↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 55.556↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.202↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 1.25↑ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 17.783↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 11.22↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Hogger P et al (1995)
acm1_human 7.35x34 400 TM7 W => F 8.128↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.862↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 4.65x65 165 TM4 Q => A 1.202↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 7.943↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 6.4↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 322 ICL3 S => A N/A N/A Lameh J et al (1992)
acm1_human 3.28x28 101 TM3 W => A 8.511↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 5.0↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 1.5↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.259↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 2.688↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 1.905↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.412↓ K(i) (Binding - Radioligand competition/displacement) Scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.40x39 405 TM7 W => A 6.897↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 162.181↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 3.236↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 2.884↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.59x59 209 TM5 W => A N/A N/A Hogger P et al (1995)
acm1_human 6.59x59 389 TM6 T => P 11.111↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 288.2↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.386↓ K(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 3.548↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.096↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.318↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 4.571↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 4.65x65 165 TM4 Q => A 1.698↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 1.235↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 34.674↓ pK(A) (Binding - Radioligand competition/displacement) Pilocarpine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.548↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.096↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 34.53x53 133 ICL2 Y => A N/A N/A Moro O et al (1994)
acm1_human 393 ECL3 D => A 1.288↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 1.23↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.202↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 10.4↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A 1.479↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 34.50x50 130 ICL2 P => A N/A N/A Moro O et al (1994)
acm1_human 7.47x47 412 TM7 T => A 1.429↑ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 171 ECL2 R => A 1.23↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 772.727↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.479↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.71x71 221 TM5 E => A N/A N/A Hogger P et al (1995)
acm1_human 5.42x43 192 TM5 T => A 1.286↓ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 21.878↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.122↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 1.0 pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.514↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.445↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 58.884↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 4.69x69 169 TM4 G => A 3.981↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.0↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A 1.905↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.025↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 2.457↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 27.542↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.445↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.44x44 374 TM6 F => A 7.752↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.39x40 189 TM5 T => A 7.413↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 21.38↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.585↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 9.12↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 34.53x53 133 ICL2 Y => A N/A N/A Moro O et al (1993)
acm1_human 3.32x32 105 TM3 D => N 10.233↓ pK(i) (Binding - Radioligand competition/displacement) McN-A343 Suga H et al (2010) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 3.631↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 1.429↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => F 10.0↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.52x52 417 TM7 C => R N/A N/A Lucas JL et al (2002)
acm1_human 7.47x47 412 TM7 T => A 2.0↑ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.38↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 9.0↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 1.513↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.259↓ pK(A) (Binding - Radioligand competition/displacement) AC-42 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 1.549↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.862↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 61.111↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.52x52 125 TM3 F => A N/A N/A Moro O et al (1994)
acm1_human 7.36x35 401 TM7 E => A 1.175↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A N/A N/A Huang XP et al (1999)
acm1_human 6.52x52 382 TM6 N => A 11000.0↓ K(i) (Binding - Radioligand competition/displacement) Trihexyphenidyl Huang XP et al (1999) Vass M et al (2018)
acm1_human 34.50x50 130 ICL2 P => A N/A N/A Moro O et al (1993)
acm1_human 3.37x37 110 TM3 N => Q 3.548↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Thal DM et al (2016) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 3.1↓ K(i) (Binding - Radioligand competition/displacement) Choline Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 1.122↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A N/A N/A Huang XP et al (1999)
acm1_human 7.46x46 411 TM7 S => A 1.5↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.52x52 125 TM3 F => A N/A N/A Moro O et al (1993)
acm1_human 7.46x46 411 TM7 S => A 1.1↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.40x39 405 TM7 W => A 16.129↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 3.715↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 5.012↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 3.162↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 1.259↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.862↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.524↑ K(i) (Binding - Radioligand competition/displacement) APE Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.15↓ K(i) (Binding - Radioligand competition/displacement) CDD-0102 Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 1.202↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 5.888↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Shockley MS et al (1997)
acm1_human 7.35x34 400 TM7 W => A 4.266↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 3.086↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.51x51 416 TM7 M => A N/A N/A Schlador ML et al (2000)
acm1_human 6.59x59 389 TM6 T => P 4.365↓ pK(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.175↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.754↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => Y N/A N/A Huang XP et al (1998)
acm1_human 394 ECL3 C => A N/A N/A Matsui H et al (1995)
acm1_human 228 ICL3 S => A 1.058↓ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.3↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 1.621↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 1.3↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A 2.63↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 5.129↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 1.047↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 272 ICL3 Y => H N/A N/A Ballesteros JA et al (2001)
acm1_human 7.31x30 396 TM7 P => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 34.6↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.585↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.905↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 330 ICL3 T => A N/A N/A Lameh J et al (1992)
acm1_human 3.28x28 101 TM3 W => A 5.623↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.862↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A 1.148↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Moro O et al (1993)
acm1_human 3.29x29 102 TM3 L => A 22.387↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 1.658↑ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 870.964↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.047↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.047↑ IC50 (Binding - Radioligand competition/displacement) Atropine Drubbisch V et al (1993) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 3.981↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Shockley MS et al (1997)
acm1_human 4.57x57 157 TM4 W => F 7.4↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 8.3↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.291↓ pK(i) (Binding - Radioligand competition/displacement) Trihexyphenidyl Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 2.239↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A N/A N/A Matsui H et al (1995)
acm1_human 3.29x29 102 TM3 L => A 2.344↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 12.303↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 2.457↑ pK(A) (Binding - Radioligand competition/displacement) AC-42 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 3.388↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 5.37↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 174 ECL2 L => P 12.589↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 9.772↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.862↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Drubbisch V et al (1993) Vass M et al (2018)
acm1_human 322 ICL3 S => A 1.058↓ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.413↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 5.37↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A N/A N/A Matsui H et al (1995)
acm1_human 2.64x63 85 TM2 Y => A 1.259↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.23↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.36x36 366 TM6 T => A 2.747↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 4.67x67 167 TM4 L => F 1.95↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 392 ECL3 K => A 2.818↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 3.89↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 6.607↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 38.019↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Moro O et al (1994)
acm1_human 3.28x28 101 TM3 W => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) Pilocarpine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P N/A N/A Huang XP et al (1999)
acm1_human 45.51x51 179 ECL2 Y => W 1.072↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 25.704↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 23.988↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 171 ECL2 R => A 3.715↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A 4.848↓ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.549↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 394 ECL3 C => A 1.445↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.44x44 374 TM6 F => A 7.407↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.65x65 215 TM5 T => A N/A N/A Lameh J et al (1992)
acm1_human 392 ECL3 K => A 1.905↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.0 pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Shockley MS et al (1997)
acm1_human 3.33x33 106 TM3 Y => A 4.571↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.43x43 116 TM3 L => H N/A N/A Ballesteros JA et al (2001)
acm1_human 2.64x63 85 TM2 Y => A 1.479↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 7.752↑ K(h) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 13.2↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A N/A N/A Matsui H et al (1995)
acm1_human 3.33x33 106 TM3 Y => A 4.365↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 5.64x64 214 TM5 E => A N/A N/A Hogger P et al (1995)
acm1_human 5.42x43 192 TM5 T => A 1.25↑ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 4.266↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 29.412↑ K(l) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.25↑ K(i) (Binding - Radioligand competition/displacement) Pilocarpine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 1.35↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A 2.041↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.047↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 3.8↓ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 4.545↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.692↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.148↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 1.846↓ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.35↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 8.13↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 3.09↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.26x26 356 TM6 S => A N/A N/A Lameh J et al (1992)
acm1_human 4.67x67 167 TM4 L => F 1.024↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 6.918↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 2.788↓ K(l) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.949↑ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 42.308↓ K(i) (Binding - Radioligand competition/displacement) p-F-HHSiD Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.128↓ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 170 ECL2 E => K 14.454↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 21.878↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A 1.413↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 7.413↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 1.818↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A N/A N/A Hogger P et al (1995)
acm1_human 7.39x38 404 TM7 Y => F 4.677↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 1.479↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) CDD-0102 Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 1.148↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 18.197↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A 2.291↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 47.863↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Suga H et al (2010) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 6.316↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Huang XP et al (1999) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 5.128↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.349↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => F 4.8↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F N/A N/A Matsui H et al (1995)
acm1_human 3.33x33 106 TM3 Y => F 2.8↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 1.259↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F N/A N/A Drubbisch V et al (1993)
acm1_human 6.58x58 388 TM6 S => Y 2.188↓ pK(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.66↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.54x54 127 TM3 V => A N/A N/A Moro O et al (1993)
acm1_human 181 ECL2 Q => A 1.445↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A 3.09↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 3.106↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Huang XP et al (1999) Vass M et al (2018)
acm1_human 284 ICL3 S => A N/A N/A Moro O et al (1993)
acm1_human 3.37x37 110 TM3 N => Q 1.023↓ pK(i) (Binding - Radioligand competition/displacement) QNB Thal DM et al (2016) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => W 1.739↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 21.878↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 2.088↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.69x69 169 TM4 G => A 4.365↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.61x61 211 TM5 I => A N/A N/A Shockley MS et al (1997)
acm1_human 3.28x28 101 TM3 W => A 77.625↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 182 ECL2 F => A 2.818↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y N/A N/A Huang XP et al (1998)
acm1_human 34.51x51 131 ICL2 L => F N/A N/A Moro O et al (1993)
acm1_human 7.31x30 396 TM7 P => A 1.585↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 43.652↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.82↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 170 ECL2 E => A 1.862↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 15.556↓ K(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 177 ECL2 Q => E 1.289↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 394 ECL3 C => A 2.137↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 8.53x53 428 H8 T => A N/A N/A Lameh J et al (1992)
acm1_human 7.35x34 400 TM7 W => A 17.783↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 13.183↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.30x30 360 TM6 E => A N/A N/A Shockley MS et al (1997)
acm1_human 34.51x51 131 ICL2 L => N N/A N/A Moro O et al (1994)
acm1_human 6.48x48 378 TM6 W => A 1.6↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.429↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.905↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.202↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.66↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 2.089↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 115.0↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.288↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 174 ECL2 L => P 1.175↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 17.378↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 34.56x56 136 ICL2 K => A N/A N/A Moro O et al (1994)
acm1_human 4.65x65 165 TM4 Q => A 1.318↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.951↓ pK(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => Y 16.218↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.50x50 71 TM2 D => N No effect IC50 (Binding - Radioligand competition/displacement) Carbachol Lameh J et al (1992) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 1.072↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.622↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 85.882↓ K(i) (Binding - Radioligand competition/displacement) Scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => Q 1.202↑ pK(A) (Binding - Radioligand saturation) [3H]QNB Thal DM et al (2016) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.318↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 4.64x64 164 TM4 W => A 5.495↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 1.479↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 3.003↑ K(i) (Binding - Radioligand competition/displacement) CDD-0078 Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.692↓ K(i) (Binding - Radioligand competition/displacement) AF-DX 116 Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 10.965↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 7.246↑ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => W 1.175↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A N/A N/A Matsui H et al (1995)
acm1_human 5.42x43 192 TM5 T => A 3.59↓ K(i) (Binding - Radioligand competition/displacement) CDD-0034 Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 1.111↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 3.6↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 1.939↓ K(l) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 5.248↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 9.772↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 22.909↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 228 ICL3 S => A N/A N/A Lameh J et al (1992)
acm1_human 177 ECL2 Q => E 1.38↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.024↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.667↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => Q 1.698↓ pK(i) (Binding - Radioligand competition/displacement) Tiotropium Thal DM et al (2016) Vass M et al (2018)
acm1_human 394 ECL3 C => A 3.636↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Shockley MS et al (1997)
acm1_human 45.52x52 180 ECL2 I => A 7.244↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 3.631↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 1.072↑ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A >100.0↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 394 ECL3 C => A 1.514↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 2.188↑ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 171 ECL2 R => A N/A N/A Matsui H et al (1995)
acm1_human 7.35x34 400 TM7 W => F 2.399↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 4.337↓ K(l) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 395 ECL3 V => A 3.548↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 4.785↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 1.35↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 174 ECL2 L => A 1.096↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.21x21 94 TM3 G => A 1.381↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.047↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 6.607↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 12.195↑ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 9.772↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 392 ECL3 K => A 2.818↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => Q 1.35↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Thal DM et al (2016) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.548↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 1.072↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 7.943↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.202↓ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 23.988↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 183 ECL2 L => A 1.82↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.175↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 2.344↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 14.791↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.815↓ K(i) (Binding - Radioligand competition/displacement) CDD-0078 Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.33x32 398 TM7 T => A 1.047↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => A 34.674↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 2.088↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 10.0↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 31.623↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Suga H et al (2013) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => E 1.122↑ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 13.49↓ pK(A) (Binding - Radioligand competition/displacement) Acetylcholine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 5.35x36 185 TM5 Q => A 1.318↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.585↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 2.755↑ pK(A) (Binding - Radioligand saturation) [3H]QNB Avlani VA et al (2010) Vass M et al (2018)
acm1_human 6.60x60 390 TM6 F => A 1.23↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.259↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 6.166↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.66x66 166 TM4 Y => A 2.455↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.096↑ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) Oxotremorine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 2.632↑ pK(A) (Binding - Radioligand competition/displacement) 77-LH-28-1 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => D N/A N/A Moro O et al (1994)
acm1_human 3.28x28 101 TM3 W => F 1.38↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 3.7↓ K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 3.236↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 284 ICL3 S => A 1.196↓ Single-point (Binding - Other) [3H]N-methyl scopolamine Moro O et al (1993) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.148↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 19.231↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A 1.259↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.175↑ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.318↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.175↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => A N/A N/A Moro O et al (1994)
acm1_human 6.52x52 382 TM6 N => A N/A N/A Huang XP et al (1999)
acm1_human 45.52x52 180 ECL2 I => A 4.367↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 371.535↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 3.333↑ K(i) (Binding - Radioligand competition/displacement) McN-A343 Bourdon H et al (1997) Vass M et al (2018)
acm1_human 172 ECL2 T => A N/A N/A Matsui H et al (1995)
acm1_human 2.64x63 85 TM2 Y => A N/A N/A Matsui H et al (1995)
acm1_human 7.39x38 404 TM7 Y => A N/A N/A Matsui H et al (1995)
acm1_human 7.36x35 401 TM7 E => A 1.318↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 97.724↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 52.308↓ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => A 660.693↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.047↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => A 1.25↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 44.668↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => F 66.1↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 7.943↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.148↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F N/A N/A Drubbisch V et al (1993)
acm1_human 45.51x51 179 ECL2 Y => A 1.096↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.549↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 1.024↑ pK(A) (Binding - Radioligand saturation) [3H]QNB Avlani VA et al (2010) Vass M et al (2018)
acm1_human 7.40x39 405 TM7 W => A 1.23↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.33x33 106 TM3 Y => F 1.3↓ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.47x47 412 TM7 T => A 1.0 K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 4.365↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.38x38 368 TM6 S => A 1.055↑ Single-point (Binding - Other) [3H]N-methyl scopolamine Lameh J et al (1992) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 5.455↓ K(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 4.651↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 3.373↓ K(l) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 4.074↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 2272.727↓ K(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => F N/A N/A Moro O et al (1994)
acm1_human 181 ECL2 Q => A 1.23↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => A 45.709↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => W 1.381↑ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 16.982↓ pK(i) (Binding - Radioligand competition/displacement) Himbacine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 2.138↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 56.234↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Suga H et al (2013) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.722↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Huang XP et al (1999) Vass M et al (2018)
acm1_human 284 ICL3 S => A N/A N/A Moro O et al (1993)
acm1_human 2.61x60 82 TM2 Y => F 2.95↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 2.138↓ pK(A) (Binding - Radioligand competition/displacement) Acetylcholine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 170 ECL2 E => A 1.047↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => Q 1.412↑ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Thal DM et al (2016) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 1.072↑ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 3.2↓ K(i) (Binding - Radioligand competition/displacement) Pilocarpine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 2.1↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 1.95↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => F 2.512↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 13.183↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 4.571↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.047↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A N/A N/A Gregory KJ et al (2010)
acm1_human 3.28x28 101 TM3 W => A 5.495↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 172 ECL2 T => A 1.023↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => A 1.698↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 174 ECL2 L => A 1.023↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 4.786↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.349↓ pK(i) (Binding - Radioligand competition/displacement) Xanomeline Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 227.273↓ K(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.479↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 18.197↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 1.905↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 20.0↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 36.667↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Shockley MS et al (1997)
acm1_human 5.42x43 192 TM5 T => A 86.275↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 4.57x57 157 TM4 W => A 3.388↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => N N/A N/A Moro O et al (1993)
acm1_human 7.33x32 398 TM7 T => A 1.413↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.50x50 71 TM2 D => N N/A N/A Lameh J et al (1992)
acm1_human 6.48x48 378 TM6 W => A 1.667↑ K(i) (Binding - Radioligand competition/displacement) Arecoline Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.62x61 83 TM2 T => A N/A N/A Matsui H et al (1995)
acm1_human 45.51x51 179 ECL2 Y => F 2.344↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 1.0 K(i) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.31x31 361 TM6 K => A N/A N/A Hogger P et al (1995)
acm1_human 182 ECL2 F => A N/A N/A Matsui H et al (1995)
acm1_human 6.59x59 389 TM6 T => P 11.482↓ pK(i) (Binding - Radioligand competition/displacement) (-)-N-methyl scopolamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.29x29 102 TM3 L => A 24.547↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.46x46 411 TM7 S => A 1.6↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 2.951↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => A 1.349↓ pK(i) (Binding - Radioligand competition/displacement) Methoctramine Matsui H et al (1995) Vass M et al (2018)
acm1_human 252 ICL3 P => A 2.188↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Sawyer GW et al (2007) Vass M et al (2018)
acm1_human 394 ECL3 C => A 1.318↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 5.623↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 4.365↓ pK(i) (Binding - Radioligand competition/displacement) l-Hyoscyamine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.32x32 105 TM3 D => N 35.481↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Suga H et al (2010) Vass M et al (2018)
acm1_human 172 ECL2 T => A 1.175↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.33x32 398 TM7 T => A N/A N/A Matsui H et al (1995)
acm1_human 3.32x32 105 TM3 D => N 11.749↓ pK(i) (Binding - Radioligand competition/displacement) McN-A343 Suga H et al (2013) Vass M et al (2018)
acm1_human 182 ECL2 F => A 3.388↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 8.182↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 3.09↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 32.258↑ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 3.311↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 10.87↑ K(i) (Binding - Radioligand competition/displacement) CDD-0034 Huang XP et al (1999) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => A 1.072↑ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 4.69x69 169 TM4 G => A 2.399↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.61x61 391 TM6 C => A 1.047↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.38↓ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 182 ECL2 F => A 1.0 pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => F 4.898↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.096↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F N/A N/A Matsui H et al (1995)
acm1_human 6.30x30 360 TM6 E => A 10.989↑ IC50 (Binding - Radioligand competition/displacement) Carbachol Hogger P et al (1995) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.667↓ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 254 ICL3 T => A 2.63↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Sawyer GW et al (2007) Vass M et al (2018)
acm1_human 34.51x51 131 ICL2 L => D N/A N/A Moro O et al (1993)
acm1_human 7.39x38 404 TM7 Y => F 6.166↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 7.762↓ pK(A) (Binding - Radioligand saturation) [3H]QNB Avlani VA et al (2010) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 3.236↓ pK(A) (Binding - Radioligand competition/displacement) Pilocarpine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.698↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.587↑ K(i) (Binding - Radioligand competition/displacement) Trihexyphenidyl Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.59x59 209 TM5 W => A N/A N/A Hogger P et al (1995)
acm1_human 23.49x49 90 ECL1 H => A 1.0 pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.32x31 397 TM7 E => A 1.023↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 2.754↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.50x50 71 TM2 D => N N/A N/A Lameh J et al (1992)
acm1_human 2.61x60 82 TM2 Y => A 1.445↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.047↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 395 ECL3 V => A 1.35↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.35x36 185 TM5 Q => A 1.096↓ pK(i) (Binding - Radioligand competition/displacement) N-methyl scopolamine Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 18.621↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.259↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => F 1.479↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 171 ECL2 R => A 3.311↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.062↓ K(h) (Binding - Radioligand competition/displacement) Carbachol Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 5.623↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y 2.899↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.202↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 9.7↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 117.49↓ pK(A) (Binding - Radioligand competition/displacement) Acetylcholine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 2.889↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.59x59 389 TM6 T => P 55.556↑ K(l) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.148↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.25↑ K(i) (Binding - Radioligand competition/displacement) 4-DAMP Bourdon H et al (1997) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.175↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.259↑ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 23.50x50 91 ECL1 W => F 6.457↓ pK(i) (Binding - Radioligand competition/displacement) 4-DAMP Matsui H et al (1995) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.479↑ pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 171 ECL2 R => A 4.169↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 4.69x69 169 TM4 G => A 1.318↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 1.996↑ pK(i) (Binding - Radioligand competition/displacement) VCP813 Keov P et al (2014) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 15.136↓ pK(b) (Binding - Radioligand competition/displacement) Benzoquinazolinone 12 Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 23.49x49 90 ECL1 H => A 1.0 pK(i) (Binding - Radioligand competition/displacement) 77-LH-28-1 Keov P et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 76.923↑ pK(A) (Binding - Radioligand competition/displacement) 77-LH-28-1 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.621↑ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 24.39↑ pK(A) (Binding - Radioligand competition/displacement) AC-42 Avlani VA et al (2010) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 2.455↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 1.23↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Keov P et al (2014) Vass M et al (2018)
acm1_human 45.52x52 180 ECL2 I => A 1.622↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 3.49x49 122 TM3 D => N N/A N/A Moro O et al (1994)
acm1_human 23.50x50 91 ECL1 W => A 37.154↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 393 ECL3 D => A 1.738↓ pK(i) (Binding - Radioligand competition/displacement) TBPB Keov P et al (2014) Vass M et al (2018)
acm1_human 184 ECL2 S => A 1.202↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 6.51x51 381 TM6 Y => A 128.825↓ pK(i) (Binding - Radioligand competition/displacement) Atropine Keov P et al (2014) Vass M et al (2018)
acm1_human 6.32x32 362 TM6 K => A N/A N/A Hogger P et al (1995)
acm1_human 7.31x30 396 TM7 P => A 1.35↑ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.441↑ K(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 1.034↓ K(i) (Binding - Radioligand competition/displacement) CDD-0098 Huang XP et al (1999) Vass M et al (2018)
acm1_human 181 ECL2 Q => A N/A N/A Matsui H et al (1995)
acm1_human 3.28x28 101 TM3 W => F 3.333↑ K(i) (Binding - Radioligand competition/displacement) Carbachol Bourdon H et al (1997) Vass M et al (2018)
acm1_human 184 ECL2 S => A N/A N/A Matsui H et al (1995)
acm1_human 45.52x52 180 ECL2 I => A 3.09↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.58x58 388 TM6 S => Y N/A N/A Huang XP et al (1999)
acm1_human 3.29x29 102 TM3 L => A 8.511↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 392 ECL3 K => A 1.413↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 7.39x38 404 TM7 Y => F 1.122↑ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A N/A N/A Leach K et al (2011)
acm1_human 7.35x34 400 TM7 W => A 13.804↓ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 6.44x44 374 TM6 F => A 5.623↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 1.835↑ K(l) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A 3.0↓ K(i) (Binding - Radioligand competition/displacement) CDD-0098 Huang XP et al (1999) Vass M et al (2018)
acm1_human 6.48x48 378 TM6 W => F 1.8↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 5.42x43 192 TM5 T => A N/A N/A Huang XP et al (1999)
acm1_human 6.58x58 388 TM6 S => Y 16.949↑ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Huang XP et al (1999) Vass M et al (2018)
acm1_human 7.36x35 401 TM7 E => A 1.862↓ pKx (Binding - Radioligand competition/displacement) MT7 Marquer C et al (2011) Vass M et al (2018)
acm1_human 2.61x60 82 TM2 Y => A 4.677↓ pK(i) (Binding - Radioligand competition/displacement) Carbachol Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 7.35x34 400 TM7 W => F 10.0↓ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 28.9↓ K(i) (Binding - Radioligand competition/displacement) Pirenzepine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 105.0↓ K(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Bourdon H et al (1997) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 154.882↓ pK(i) (Binding - Radioligand competition/displacement) Pirenzepine Matsui H et al (1995) Vass M et al (2018)
acm1_human 2.64x63 85 TM2 Y => A 1.862↓ pK(d) (Binding - Radioligand saturation) [3H]QNB Keov P et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 23.529↓ K(i) (Binding - Radioligand competition/displacement) Acetylcholine Huang XP et al (1999) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => A 50.0↑ pK(i) (Binding - Radioligand competition/displacement) VCP794 Keov P et al (2014) Vass M et al (2018)
acm1_human 181 ECL2 Q => A 1.318↓ pK(A) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 3.37x37 110 TM3 N => A 31.7↓ K(i) (Binding - Radioligand competition/displacement) Oxotremorine-M Bourdon H et al (1997) Vass M et al (2018)
acm1_human 45.51x51 179 ECL2 Y => A 1.38↓ pK(b) (Binding - Radioligand competition/displacement) BQCA Abdul-Ridha A et al (2014) Vass M et al (2018)
acm1_human 6.52x52 382 TM6 N => A 9.688↓ K(d) (Binding - Radioligand saturation) [3H](R)-QNB Huang XP et al (1999) Vass M et al (2018)
acm1_human 2.56x551 77 TM2 F => I 1.175↓ pK(A) (Binding - Radioligand competition/displacement) Pilocarpine Avlani VA et al (2010) Vass M et al (2018)
acm1_human 171 ECL2 R => A 3.021↑ pK(i) (Binding - Other) Gallamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 184 ECL2 S => A 2.399↓ pK(i) (Binding - Radioligand competition/displacement) Acetylcholine Matsui H et al (1995) Vass M et al (2018)
acm1_human 3.28x28 101 TM3 W => F 1.23↓ pK(d) (Binding - Radioligand saturation) [3H]N-methyl scopolamine Matsui H et al (1995) Vass M et al (2018)
acm1_human 7.31x30 396 TM7 P => A