Mutant Browser

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Protein name Generic number Position Segment Mutation FoldChange or Qual Exp Type Ligand Reference Review
Protein name Generic number Segment Position Mutation FoldChange or Qual Exp Type Ligand Reference Review
acthr_mouse 6.24x24 208 TM6 S => A N/A N/A Baig AH et al (2001)
acthr_mouse 6.24x24 208 TM6 S => A N/A N/A Baig AH et al (2001)


Residue

Diagrams

ICL1 K N L Q ICL1ECL1 N M G Y L K P R ECL1ICL2 A L Q Y H S I V ICL2ECL2 H ECL2ICL3 A R K I ICL3ECL3 P N N P Y C V C Y M S ECL3N-term M K H I I N S Y E H T N D T A R N N S D C P D V V L N-termC-term R Y C-term P E E I F F T I S V I G I L E N L I V L L A V I K N S P M Y F F I C S L A I S D M L G S L Y K I L E N I L I M F R G S F E S T A D D I I D C M F I L S L L G S I F S L S V I A A D R Y I T I F H T M R R T I I T L T I I W M F C T G S G I T M V I F S H I P T V L T F T S L F P L M L V F I L C L Y I H M F L L A R S H S T L P R T N M K G A M T L T I L L G V F I F C W A P F V L H V L L M T F C L F Q V N G M L I M C N A V I D P F I Y A F R S P E F K R N L R D A M L F C
Download: PNG | SVG Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
L N E L I G I V S I T F F I E E P 1 C S L A I S D M L G S L Y K I L E N I L 2 V S L S F I S G L L S L I F M C D I I D 3 T I I T L T I I W M F C T G S G I T M V 4 Y L C L I F V L M L P F L S T F T L V T 5 T I L L G V F I F C W A P F V L H V L L 6 F P D I V A N C M I L M G N V Q F L 7
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Residue Table


GPCRdb(A)
GPCRdb(A)
MC2 receptor
TM6
6x24 6.24x24 S208