Mutant Browser

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Protein name Generic number Position Segment Mutation FoldChange or Qual Exp Type Ligand Reference Review
Protein name Generic number Segment Position Mutation FoldChange or Qual Exp Type Ligand Reference Review
bkrb1_rat 7.54x54 323 TM7 V => S N/A N/A Faussner A et al (2005)
bkrb1_rat 1.59x59 63 TM1 L => N N/A N/A Yu J et al (2005)


Residue

Diagrams

ICL1 Q W R Q W W W Q Q R Q R Q R L ICL1ECL1 R F N W P F ECL1ICL2 P M T S W G Y R ICL2ECL2 S V K V V P D L N V S A C I L L F P H E A ECL2ICL3 K E A S R ICL3ECL3 V I Q ECL3N-term M A S E V L L E L Q P S N R S L Q A P A N I T S C E S A L E D N-term W D L L Y R V L P G F V I T I C F F G L L G N L L V L S F F L L P T I A E I Y L A N L A A S D L V F V L G L P F W A E N I G N G T D L C R V V S G V I K A N L F V S I F L V V A I S Q D R Y R L L V Y R R R Q A Q A T C L L I W V A G G L L S I P T F L L R W H F A R M V E L N V L G F L L P V T A I I F F N Y H I L A S L R G Q T R C G G P K G S K T T G L I L T L V A S F L V C W C P Y H F F A F L D F L V Q V R D C S W K E I T D L G L Q L A N F F A F V N S C L N P L I Y V F A G R L V L G L K T R T L
Download: PNG | SVG Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
L N G L L G F F C I T I V F G P L V R Y 1 A N L A A S D L V F V L G L P F W A E N 2 A V V L F I S V F L N A K I V G S V V R 3 A Q A T C L L I W V A G G L L S I P T 4 N F F I I A T V P L L F G L V N L E V M R 5 L T L V A S F L V C W C P Y H F F A F L 6 L P N L C S N V F A F F N A L Q L G L 7
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Residue Table


GPCRdb(A)
GPCRdb(A)
B1 receptor
TM1
1x59 1.59x59 L63
TM7
7x54 7.54x54 V323