Mutant Browser

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Protein name Generic number Position Segment Mutation FoldChange or Qual Exp Type Ligand Reference Review
Protein name Generic number Segment Position Mutation FoldChange or Qual Exp Type Ligand Reference Review
mas_human 2.37x37 64 TM2 N => D N/A N/A Kreiss M et al (2004)
mas_human 182 ECL2 N => S N/A N/A Newbolt A et al (1998)


Residue

Diagrams

ICL1 M R R ICL1ECL1 Y E L ECL1ICL2 P I W Y R C H R ICL2ECL2 I D R E E E S H S R N D C ECL2ICL3 A S H ICL3ECL3 W S T F ECL3N-term M D G S N V T S F V V E E P T N I S T G R N A S V G N N-termC-term L T R A F K D E M Q P R R Q K D N C N T V T V E T V V C-term A H R Q I P I V H W V I M S I S P V G F V E N G I L L W F L C F R N P F T V Y I T H L S I A D I S L L F C I F I L S I D Y A L D S S G H Y Y T I V T L S V T F L F G Y N T G L Y L L T A I S V E R C L S V L Y P K Y Q S A L V C A L L W A L S C L V T T M E Y V M C R A V I I F I A I L S F L V F T P L M L V S S T I L V V K I R K N T W S S K L Y I V I M V T I I I F L I F A M P M R L L Y L L Y Y E Y G N L H H I S L L F S T I N S S A N P F I Y F F V G S S F K E V K K K R S L K V
Download: PNG | SVG Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
G N E V F G V P S I S M I V W H V I P I 1 T H L S I A D I S L L F C I F I L S I D 2 A T L L Y L G T N Y G F L F T V S L T V 3 S A L V C A L L W A L S C L V T T M E Y 4 I T S S V L M L P T F V L F S L I A I F I 5 M V T I I I F L I F A M P M R L L Y L L 6 F P N A S S N I T S F L L S I H H L N 7
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Residue Table


GPCRdb(A)
GPCRdb(A)
MAS1
TM2
2x37 2.37x37 N64