Mutant Browser

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Protein name Generic number Position Segment Mutation FoldChange or Qual Exp Type Ligand Reference Review
Protein name Generic number Segment Position Mutation FoldChange or Qual Exp Type Ligand Reference Review
pf2r_human 3.49x49 132 TM3 E => T N/A N/A Pathe-Neuschafer-Rube A et al (2005)


Residue

Diagrams

ICL1 Q R F R ICL1ECL1 D K E W I R ECL1ICL2 P I F H S T K I ICL2ECL2 H R D Y K I Q A S R T W C F Y N T E D I K D W E D ECL2ICL3 H R Q G R S ICL3ECL3 G N H S L E ECL3N-term M S M N N S K Q L V S P A A A L L S N T T C Q T E N R L N-termC-term I S L H I W E L S S I K N S L K V A A I S E S P V A E K S A S T C-term S V F F S V I F M T V G I L S N S L A I A I L M K A Y Q K S K A S F L L L A S G L V I T D F F G H L I N G A I A V F V Y A S F D Q S N V L C S I F G I C M V F S G L C P L L L G S V M A I E R C I G V T K T S K H V K M M L S G V C L F A V F I A L L P I L G R F Y L L L F S F L G L L A L G V S L L C N A I T G I T L L R V K F K S Q Q H H L E M V I Q L L A I M C V S C I C W S P F L V T M A N I G I N T C E T T L F A L R M A T W N Q I L D P W V Y I L L R K A L Y K C C G V L K N L A S Q V H V
Download: PNG | SVG Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
S N S L I G V T M F I V S F F V S 1 S G L V I T D F F G H L I N G A I A V F 2 V S G L L L P C L G S F V M C I G F I S 3 V K M M L S G V C L F A V F I A L L P I 4 I A N C L L S V G L A L L G L F S F L L 5 L A I M C V S C I C W S P F L V T M A N 6 W P D L I Q N W T A M R L A F L T T E 7
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Residue Table


GPCRdb(A)
GPCRdb(A)
FP receptor
TM3
3x49 3.49x49 E132