LPA6 receptor (lpar6_chick)

FAMILY

Class A (Rhodopsin) Lipid receptors Lysophospholipid (LPA) receptors LPA6 receptor

GENE

LPAR6 (P2RY5)

ORGANISM

Chicken (Gallus gallus)

ALT. NAMES

Lysophosphatidic acid receptor 6, LPA receptor 6, LPA-6, Oleoyl-L-alpha-lysophosphatidic acid receptor, P2Y purinoceptor 5, P2Y5, Purinergic receptor 5

SOURCE

SWISSPROT

SEQUENCE

N-term TM1  
M
V
S
S
N
C
S
T
E
D
10
                   
S
F
K
Y
T
L
Y
G
C
V
20
                   
F
S
M
V
F
V
L
G
L
I
30
                   
A
N
C
V
A
I
Y
I
F
T
40
    ICL1 TM2  
F
T
L
K
V
R
N
E
T
T
50
                   
T
Y
M
L
N
L
A
I
S
D
60
                   
L
L
F
V
F
T
L
P
F
R
70
            ECL1
I
Y
Y
F
V
V
R
N
W
P
80
  TM3            
F
G
D
V
L
C
K
I
S
V
90
                   
T
L
F
Y
T
N
M
Y
G
S
100
                   
I
L
F
L
T
C
I
S
V
D
110
                   
R
F
L
A
I
V
H
P
F
R
120
ICL2   TM4    
S
K
T
L
R
T
K
R
N
A
130
                   
R
I
V
C
V
A
V
W
I
T
140
                   
V
L
A
G
S
T
P
A
S
F
150
  ECL2          
F
Q
S
T
N
R
Q
N
N
T
160
                   
E
Q
R
T
C
F
E
N
F
P
170
TM5              
E
S
T
W
K
T
Y
L
S
R
180
                   
I
V
I
F
I
E
I
V
G
F
190
                   
F
I
P
L
I
L
N
V
T
C
200
                   
S
T
M
V
L
R
T
L
N
K
210
  ICL3 TM6    
P
L
T
L
S
R
N
K
L
S
220
                   
K
K
K
V
L
K
M
I
F
V
230
                   
H
L
V
I
F
C
F
C
F
V
240
                   
P
Y
N
I
T
L
I
L
Y
S
250
          ECL3  
L
M
R
T
Q
T
W
I
N
C
260
TM7              
S
V
V
T
A
V
R
T
M
Y
270
                   
P
V
T
L
C
I
A
V
S
N
280
                   
C
C
F
D
P
I
V
Y
Y
F
290
  H8              
T
S
D
T
N
S
E
L
D
K
300
        C-term
K
Q
Q
V
H
Q
N
T

LINKS

UniProt

DIAGRAMS

ICL1 L K V R ICL1ECL1 R N W P F ECL1ICL2 P F R S K T L R ICL2ECL2 Q S T N R Q N N T E Q R T C F E N F P ECL2ICL3 L T L ICL3ECL3 T W I ECL3N-term M N-termC-term H Q N T C-term V S S N C S T E D S F K Y T L Y G C V F S M V F V L G L I A N C V A I Y I F T F T N E T T T Y M L N L A I S D L L F V F T L P F R I Y Y F V V G D V L C K I S V T L F Y T N M Y G S I L F L T C I S V D R F L A I V H T K R N A R I V C V A V W I T V L A G S T P A S F F E S T W K T Y L S R I V I F I E I V G F F I P L I L N V T C S T M V L R T L N K P S R N K L S K K K V L K M I F V H L V I F C F C F V P Y N I T L I L Y S L M R T Q N C S V V T A V R T M Y P V T L C I A V S N C C F D P I V Y Y F T S D T D K K N S E L Q Q V
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

C N A I L G L V F V M S F V C G Y L T Y 1 L N L A I S D L L F V F T L P F R I Y Y 2 C T L F L I S G Y M N T Y F L T V S I K 3 A R I V C V A V W I T V L A G S T P A 4 S C T V N L I L P I F F G V I E I F I V I 5 F V H L V I F C F C F V P Y N I T L I L 6 I P D F C C N S V A I C L T V P Y M T 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

ENDOGENOUS LIGANDS

No endogenous ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available